The Global Navigation Satellite System(GNSS)has been widely adopted in numerous fields,including intelligent transportation,remote sensing,and aeronautical and astronautical engineering.As new navigation approaches,te...The Global Navigation Satellite System(GNSS)has been widely adopted in numerous fields,including intelligent transportation,remote sensing,and aeronautical and astronautical engineering.As new navigation approaches,technologies,and applications continue to emerge,they attract significant global attention.Ensuring reliable positioning solutions with high accuracy,strong anti-interference capabilities,high availability and low integrity risks has become increasingly critical.展开更多
Nitrite reductases(NiRs)are natural enzymes that facilitate the reduction of nitrite.They are essential for the microbial nitrogen cycle and play a vital role in regulating numerous physiological and pathological proc...Nitrite reductases(NiRs)are natural enzymes that facilitate the reduction of nitrite.They are essential for the microbial nitrogen cycle and play a vital role in regulating numerous physiological and pathological processes associated with nitric oxide(NO)in living organisms.By the merits of protein engineering,a variety of artificial NiR mimics have been developed.These include traditional artificial proteins,metal-azacycle complexes,and nanozymes such as metal,metal oxide/sulfide nanoparticles,metal-organic frameworks,bioinorganic nanohybrids,and advanced single-atom nanozymes.This development marks an important milestone in broadening the application of enzyme-like catalytic nitrite reduction across various fields,such as biomedicine,biosensing,food science,and environmental science.In this review,we first outline the different types of NiRs,along with their active center structures and catalytic mechanisms,drawing from recent research and discoveries.We then classify the reported NiR mimic materials,discussing their active center structures and enzyme-like catalytic mechanisms.Additionally,we explore the potential future applications and challenges facing NiR mimics in the field of biomedicine.展开更多
文摘The Global Navigation Satellite System(GNSS)has been widely adopted in numerous fields,including intelligent transportation,remote sensing,and aeronautical and astronautical engineering.As new navigation approaches,technologies,and applications continue to emerge,they attract significant global attention.Ensuring reliable positioning solutions with high accuracy,strong anti-interference capabilities,high availability and low integrity risks has become increasingly critical.
基金support from the National Natural Science Foundation of China(32371407,32222041,and 82160421)the Natural Science Foundation of Jiangsu Province(BK20220059)the“Jiangsu Specially Appointed Professor”Program.This work is supported by the Jilin Provincial Key Laboratory of Western Jilin’s Clean Energy(YDZJ202502CXJD010).
文摘Nitrite reductases(NiRs)are natural enzymes that facilitate the reduction of nitrite.They are essential for the microbial nitrogen cycle and play a vital role in regulating numerous physiological and pathological processes associated with nitric oxide(NO)in living organisms.By the merits of protein engineering,a variety of artificial NiR mimics have been developed.These include traditional artificial proteins,metal-azacycle complexes,and nanozymes such as metal,metal oxide/sulfide nanoparticles,metal-organic frameworks,bioinorganic nanohybrids,and advanced single-atom nanozymes.This development marks an important milestone in broadening the application of enzyme-like catalytic nitrite reduction across various fields,such as biomedicine,biosensing,food science,and environmental science.In this review,we first outline the different types of NiRs,along with their active center structures and catalytic mechanisms,drawing from recent research and discoveries.We then classify the reported NiR mimic materials,discussing their active center structures and enzyme-like catalytic mechanisms.Additionally,we explore the potential future applications and challenges facing NiR mimics in the field of biomedicine.
