A physiological state of＂normoxia＂obtains when tissue oxygen tension（pO_2）is sufficient to drive mitochondrial respiration throughout a volume of cells.Between 30-40%of the available oxygen is normally extracted f...A physiological state of＂normoxia＂obtains when tissue oxygen tension（pO_2）is sufficient to drive mitochondrial respiration throughout a volume of cells.Between 30-40%of the available oxygen is normally extracted from hemoglobin as it passes through neural tissue.展开更多
Hardship The Double Take column looks at a single topic from an African and Chinese perspective.This month,we explore whether enduring hardship is still a necessary path to growth in a changing world.
1 Originally published in 1993,To Live,a novel by Chinese author Yu Hua has since gained international recognition for its raw emotional depth and exploration of themes like fate,endurance and the essence of humanity....1 Originally published in 1993,To Live,a novel by Chinese author Yu Hua has since gained international recognition for its raw emotional depth and exploration of themes like fate,endurance and the essence of humanity.2 The novel follows the life of Xu Fugui,a once⁃wealthy landowner who lost his fortune through gambling(赌博).As his status shifted to that of a peasant,he witnessed the rapid changes of society.Despite enduring relentless hardship,Fugui survived,finding moments of comfort in small and everyday acts of perseverance.展开更多
Background:Despite the wide use of compression garments to enhance athletic running performance,evidence supporting improvements has not been conclusive.This updated systematic review and meta-analysis of randomized c...Background:Despite the wide use of compression garments to enhance athletic running performance,evidence supporting improvements has not been conclusive.This updated systematic review and meta-analysis of randomized controlled trials(RCTs)compared the effects of compression garment wearing with those of non-compression garment wearing(controls)during running on improving running performance.Methods:A comprehensive search was conducted in the electronic databases(Web of Science,EBSCOhost,PubMed,Embase,Scopus,and Cochrane)for RCTs comparing running performance between runners wearing compression garments and controls during running,from inception to September 2024.Independent reviewers screened studies,extracted data,appraised risk of bias(RoB 2)and certainty of evidence(Grading of Recommendations Assessments,Development and Evaluation(GRADE)).Primary outcomes were race time and time to exhaustion.Secondary outcomes covered running speed and race pace,submaximal oxygen uptake,tissue oxygenation,and soft tissue vibration.Randomeffects meta-analyses were conducted to generate pooled estimates,expressed in standardized mean difference(SMD).Subgroup differences of garment,race type,and contact surface were tested in moderator analyses.Results:The search yielded 51 eligible studies comprising 899 participants,of which 33 studies were available for meta-analysis of primary outcomes.Runners wearing compression garments during running showed no significant improvement in race time(SMD=-0.07,95%CI:-0.22 to 0.09;p=0.40)or time to exhaustion(SMD=0.04,95%CI:-0.20 to 0.29;p=0.72).Moderator analyses indicated no effects from garment type,race type,or surface.Secondary outcomes also showed no performance benefits,although compression garments significantly reduced soft tissue vibration(SMD=-0.43,95%CI:-0.70 to-0.15;p<0.01).Certainty of evidence was rated low to very low.Conclusion:Data synthesis of current RCTs offers no updated evidence favoring the support of wearing compression garments during running as a viable strategy for improving running and endurance performance among runners of varying performance levels and types of running races.展开更多
Background:Sport climbing is becoming incredibly popular both in the general population and among athletes.No consensus exists regarding evidence-based sport-specific performance evaluation;therefore,this systematic r...Background:Sport climbing is becoming incredibly popular both in the general population and among athletes.No consensus exists regarding evidence-based sport-specific performance evaluation;therefore,this systematic review was aimed at analyzing determinants of sport climbing performance and evaluation methods by comparing climbers of different levels.Methods:PubMed,Scopus,and Web of Science were searched up to December 20,2022.Studies providing the self-reported climbing ability associated with different functional outcomes in groups of climbers of contiguous performance levels were eligible.Results:74 studies were finally included.Various methods have been proposed to evaluate determinants of sport climbing performance.Climbing-specific assessments were able to discriminate climbers of different levels when compared to general functional tests.Test validity resulted high for climbing-specific cardiorespiratory endurance as well as muscular-strength,-endurance,and-power;similarly,reliability was good except for cardiorespiratory endurance.Climbing-specific flexibility assessment resulted in high reliability but moderate validity,whereas balance showed low validity.Considerable conflicting evidence was found regarding anthropometric characteristics.Conclusion:The present analysis identified cardiorespiratory endurance as well as muscular-strength,-endurance,and-power as determinants of sport climbing performance.In contrast,balance,flexibility,and anthropometric characteristics seem to count less.This review also proposes an evidence-based Functional Sport Climbing test battery for asses sing performance determinants,which includes tests that have been identified to be valid,reliable,and feasible.While athletes and coaches should rely on evidence-based and standardized evaluation methods,researchers may design specific large-scale trials as a resource for providing additional,homogenous,and comparable data to improve scientific evidence and professionalism in this popular sport discipline.展开更多
Rainbows-symbolizing peace,hope,promise and endurance(忍耐力)in hard times-are springing up in neighborhoods throughout Long Island in an effort to color the future road with optimism.The campaign,Rainbows over Nassau...Rainbows-symbolizing peace,hope,promise and endurance(忍耐力)in hard times-are springing up in neighborhoods throughout Long Island in an effort to color the future road with optimism.The campaign,Rainbows over Nassau and Suffolk Counties and Beyond,started on March 21 and spread through a group.It's a campaign that encourages participants to make rainbows to display outside their homes,anywhere from their front windows and doors to lawns and sidewalks.It follows another similar project,Chalk Your Walk,which promotes writing hopeful messages in chalk on driveways and sidewalks.展开更多
Unmanned aerial vehicles(UAVs)technology is rapidly advancing,offering innovative solutions for various industries,including the critical task of oil and gas pipeline surveillance.However,the limited flight time of co...Unmanned aerial vehicles(UAVs)technology is rapidly advancing,offering innovative solutions for various industries,including the critical task of oil and gas pipeline surveillance.However,the limited flight time of conventional UAVs presents a significant challenge to comprehensive and continuous monitoring,which is crucial for maintaining the integrity of pipeline infrastructure.This review paper evaluates methods for extending UAV flight endurance,focusing on their potential application in pipeline inspection.Through an extensive literature review,this study identifies the latest advancements in UAV technology,evaluates their effectiveness,and highlights the existing gaps in achieving prolonged flight operations.Advanced techniques,including artificial intelligence(AI),machine learning(ML),and deep learning(DL),are reviewed for their roles in pipeline monitoring.Notably,DL algorithms like You Only Look Once(YOLO)are explored for autonomous flight in UAV-based inspections,real-time defect detection,such as cracks,corrosion,and leaks,enhancing reliability and accuracy.A vital aspect of this research is the proposed deployment of a hybrid drone design combining lighter-than-air(LTA)and heavier-than-air(HTA)principles,achieving a balance of endurance and maneuverability.LTA vehicles utilize buoyancy to reduce energy consumption,thereby extending flight durations.The paper details the methodology for designing LTA vehicles,presenting an analysis of design parameters that align with the requirements for effective pipeline surveillance.The ongoing work is currently at Technology Readiness Level(TRL)4,where key components have been validated in laboratory conditions,with fabrication and flight testing planned for the next phase.Initial design analysis indicates that LTA configurations could offer significant advantages in flight endurance compared to traditional UAV designs.These findings lay the groundwork for future fabrication and testing phases,which will be critical in validating and assessing the proposed approach’s real-world applicability.By outlining the technical complexities and proposing specialized techniques tailored for pipeline monitoring,this paper provides a foundational framework for advancing UAV capabilities in the oil and gas sector.Researchers and industry practitioners can use this roadmap to further develop UAV-enabled surveillance solutions,aiming to improve the reliability,efficiency,and safety of pipeline monitoring.展开更多
BACKGROUND In pediatric and adolescent athletes,there is a lack of understanding about the impact of factors such as race on the structural or cardiovascular adaptations in response to exercise which may unnecessarily...BACKGROUND In pediatric and adolescent athletes,there is a lack of understanding about the impact of factors such as race on the structural or cardiovascular adaptations in response to exercise which may unnecessarily disqualify athletes from the competitive sport.We hypothesized that race has an impact on cardiac adaptions in non-adult athletes.AIM To explore the racial disparity in electrocardiographic(ECG)and echocardiographic(ECHO)parameters in healthy adolescent athletes.METHODS A comprehensive electronic systematic literature search using MEDLINE database was performed from inception to September 20,2024.Inclusion criteria included randomized or observational cohort studies that recruited adolescent competitive athletes in any sport discipline and compared between the Black and White races with an age range of 12-18 years.RESULTS Of 723 records that were identified by the literature search,seven studies(n=5036)were included.The mean age was 13.0-18.0 years old with male predominance.Black athletes had significantly longer PR interval[mean difference(MD)=17.49 millisecond,95% CI:11.70-23.29]and shorter QRS complex duration(MD=-7.35 millisecond,95% CI:-9.17 to-5.53)and corrected QT interval(MD=-4.95 millisecond,95% CI:-7.69 to-2.22)than the White athletes.Black athletes were approximately four times more likely to have first-degree atrioventricular(AV)block,inverted T wave,ST-segment elevation,and left atrium(LA)enlargement than their White counterparts.In terms of ECHO parameters,Black athletes had significantly greater septal wall thickness(MD=0.85 mm,95% CI:0.62-1.07),posterior wall thickness(MD=1.07 mm,95% CI:0.36-1.78),relative wall thickness(MD=0.03,95%CI:0.001-0.06),maximal wall thickness(MD=1.05 mm,95%CI:0.28-1.83),and LA diameter(MD=1.64 mm,95%CI:0.16-3.12).CONCLUSION Race has an impact on the ECG and ECHO parameters that reflect cardiac adaptations in adolescent athletes.Black athletes tend to have an increased prevalence of distinct ECG changes such as first-degree AV block and T-wave inversions compared with their White counterparts.Despite having thicker septal and posterior walls,the overall prevalence of left ventricular hypertrophy did not differ between the races.展开更多
Tennis,a popular sport in colleges and universities,is deeply loved by teachers and students.However,due to its high physical demands,technical difficulty,and other characteristics,it requires a high level of physical...Tennis,a popular sport in colleges and universities,is deeply loved by teachers and students.However,due to its high physical demands,technical difficulty,and other characteristics,it requires a high level of physical fitness.Compared to competitive tennis,although college tennis instruction may lack competitiveness and involve lower exercise intensity,it still necessitates regular physical training to enhance body coordination,balance,and agility.This can help students stay physically fit while avoiding injuries.This article explores the content of physical training in college tennis instruction,clarifies the important role of physical training,and summarizes a series of physical training pathways to provide reference support for physical training in college tennis instruction.展开更多
BACKGROUND Lung cancer is one of the most common and deadly cancers worldwide.As the disease progresses and due to the side effects of treatment,patients’physical activity significantly decreases.AIM To systematicall...BACKGROUND Lung cancer is one of the most common and deadly cancers worldwide.As the disease progresses and due to the side effects of treatment,patients’physical activity significantly decreases.AIM To systematically review and conduct a meta-analysis on the effects of exercise rehabilitation on the physical activity of lung cancer patients and determine the best implementation methods to provide clinical guidance.METHODS Literature was searched through multiple electronic databases.A random effects model was used to combine effect sizes through standardized mean difference(SMD).The Cochrane risk of bias tool was used to assess the quality of the lite-rature,sensitivity analysis was used to ensure the robustness of the results,and Egger’s test was used to detect publication bias and asymmetry.RESULTS A total of 11 studies involving 541 patients were included in this study.The phy-sical endurance,muscle function and cardiopulmonary function of non-small cell lung cancer(NSCLC)patients were evaluated.The overall effect size of the six-minute walk test(6MWT)was not statistically significant.However,subgroup analysis found that endurance significantly improved when exercise duration exceeded 0.5 hours(P≤0.05).In terms of muscle function,the overall effect size was SMD=0.619.Subgroup analysis showed that strength training,respiratory training,and cross-training(XT)significantly improved muscle function.Exercise rehabilitation significantly enhanced cardiopulmonary endurance(SMD=0.856,P=0.002),and the effect was better when the single exercise duration was more than 1 hour,age was over 65 years,and the intervention period was more than 3 months.CONCLUSION Exercise rehabilitation effectively improved muscle function in NSCLC patients,especially strength training,respiratory training,and cross-training.Cardiopulmonary function also showed improvement,particularly when exercise duration exceeded 1 hour,age was≥65 years,and the intervention period was more than 3 months.A single exercise duration of more than 0.5 hours can enhance patients’physical endurance.Appropriately increasing exercise duration and selecting suitable exercise forms can effectively improve the physical activity of NSCLC patients.展开更多
2025年6月5日,米其林宣布,正在推出全新Pilot Sport Endurance 2026系列轮胎,该系列专为超跑设计,将在克莱蒙费朗的卡塔鲁工厂生产。米其林表示,这款光面轮胎系列是该集团在可持续发展承诺中的重要进步,其目标是在轮胎成分中融入50%的...2025年6月5日,米其林宣布,正在推出全新Pilot Sport Endurance 2026系列轮胎,该系列专为超跑设计,将在克莱蒙费朗的卡塔鲁工厂生产。米其林表示,这款光面轮胎系列是该集团在可持续发展承诺中的重要进步,其目标是在轮胎成分中融入50%的可持续材料(可再生材料和回收材料)。展开更多
On a summer morning in Boqiang Village,tucked beneath the emerald mountains of Fanshi County,Shanxi Province,the Ultra Trail Mount Wutai 2025 commenced with the sound of the starting pistol-an event that was much more...On a summer morning in Boqiang Village,tucked beneath the emerald mountains of Fanshi County,Shanxi Province,the Ultra Trail Mount Wutai 2025 commenced with the sound of the starting pistol-an event that was much more than just a competition.As soon as the colourful smoke bombs lit up the sky,some 2,000 runners from China and abroad set off to reach one of the country’s most sacred Buddhist peaks.Over the past decade,this race has become a fixture on the global running calendar and a symbol of the growing popularity of endurance sports.展开更多
This study proposes a method for calculating the probability distribution of structural responses at different intensities using the endurance time(ET)method.The results can be used to calculate the fragility curve of...This study proposes a method for calculating the probability distribution of structural responses at different intensities using the endurance time(ET)method.The results can be used to calculate the fragility curve of structural collapse.The ET method involves dynamic analysis of a structure under an intensifying record over time.While conventional ET methods can determine the median of the structural response,they lack the ability to calculate its dispersion.To address this limitation,the present study utilizes ET analysis and single-degree-of-freedom(SDOF)systems to develop a method that considers the record-to-record variability for calculating the probability distribution of structural response.The accuracy of this method is evaluated by comparing it with the incremental dynamic analysis(IDA)method using special moment frames.The results demonstrate that the proposed method achieves a reasonably accurate estimation of dispersion while significantly reducing the computational burden(by approximately 95%)compared to the IDA method.展开更多
In the terraced fields in Honghe Hani and Yi Autonomous Prefecture,southwest China’s Yunnan Province,the morning mist drifts up from the valleys while the tiered ridges spread like the fingerprints of the earth.
Background:This study aimed to determine the effect of different carbohydrate(CHO)doses on exercise capacity in patients with McArdle disease—the paradigm of“exercise intolerance”,characterized by complete muscle g...Background:This study aimed to determine the effect of different carbohydrate(CHO)doses on exercise capacity in patients with McArdle disease—the paradigm of“exercise intolerance”,characterized by complete muscle glycogen unavailability—and to determine whether higher exogenous glucose levels affect metabolic responses at the McArdle muscle cell(in vitro)level.Methods:Patients with McArdle disease(n=8)and healthy controls(n=9)underwent a 12-min submaximal cycling constant-load bout followed by a maximal ramp test 15 min after ingesting a non-caloric placebo.In a randomized,double-blinded,cross-over design,patients repeated the tests after consuming either 75 g or 150 g of CHO(glucose:fructose=2:1).Cardiorespiratory,biochemical,perceptual,and electromyographic(EMG)variables were assessed.Additionally,glucose uptake and lactate appearance were studied in vitro in wild-type and McArdle mouse myotubes cultured with increasing glucose concentrations(0.35,1.00,4.50,and 10.00 g/L).Results:Compared with controls,patients showed the“classical”second-wind phenomenon(after prior disproportionate tachycardia,myalgia,and excess electromyographic activity during submaximal exercise,all p<0.05)and an impaired endurance exercise capacity(-51%ventilatory threshold and55%peak power output,both p<0.001).Regardless of the CHO dose(p<0.05 for both doses compared with the placebo),CHO intake increased blood glucose and lactate levels,decreased fat oxidation rates,and attenuated the second wind in the patients.However,only the higher dose increased ventilatory threshold(+27%,p=0.010)and peak power output(+18%,p=0.007).In vitro analyses revealed no differences in lactate levels across glucose concentrations in wild-type myotubes,whereas a doseresponse effect was observed in McArdle myotubes.Conclusion:CHO intake exerts beneficial effects on exercise capacity in McArdle disease,a condition associated with total muscle glycogen unavailability.Some of these benefits are dose dependent.展开更多
With the rapid development of machine learning,the demand for high-efficient computing becomes more and more urgent.To break the bottleneck of the traditional Von Neumann architecture,computing-in-memory(CIM)has attra...With the rapid development of machine learning,the demand for high-efficient computing becomes more and more urgent.To break the bottleneck of the traditional Von Neumann architecture,computing-in-memory(CIM)has attracted increasing attention in recent years.In this work,to provide a feasible CIM solution for the large-scale neural networks(NN)requiring continuous weight updating in online training,a flash-based computing-in-memory with high endurance(10^(9) cycles)and ultrafast programming speed is investigated.On the one hand,the proposed programming scheme of channel hot electron injection(CHEI)and hot hole injection(HHI)demonstrate high linearity,symmetric potentiation,and a depression process,which help to improve the training speed and accuracy.On the other hand,the low-damage programming scheme and memory window(MW)optimizations can suppress cell degradation effectively with improved computing accuracy.Even after 109 cycles,the leakage current(I_(off))of cells remains sub-10pA,ensuring the large-scale computing ability of memory.Further characterizations are done on read disturb to demonstrate its robust reliabilities.By processing CIFAR-10 tasks,it is evident that~90%accuracy can be achieved after 109 cycles in both ResNet50 and VGG16 NN.Our results suggest that flash-based CIM has great potential to overcome the limitations of traditional Von Neumann architectures and enable high-performance NN online training,which pave the way for further development of artificial intelligence(AI)accelerators.展开更多
Manned multi-rotor electric Vertical Takeoff and Landing(eVTOL)aircraft is prone to actuator saturation due to its weak yaw control efficiency.To address this inherent problem,a rotor cross-tilt configuration is appli...Manned multi-rotor electric Vertical Takeoff and Landing(eVTOL)aircraft is prone to actuator saturation due to its weak yaw control efficiency.To address this inherent problem,a rotor cross-tilt configuration is applied in this paper,with an optimization method proposed to improve the overall control efficiency of the vehicle.First,a flight dynamics model of a 500-kg manned multi-rotor eVTOL aircraft is established.The accuracy of the co-axial rotor model is verified using a single arm test bench,and the accuracy of the flight dynamics model is verified by the flight test data.Then,an optimization method is designed based on the flight dynamics model to calculate an optimal rotor cross-tilt mounting angle,which not only improves the yaw control efficiency,but also basically maintains the efficiency of other control channels.The ideal rotor cross-tilt mounting angle for the prototype is determined by comprehensively considering the optimal results with different payloads,forward flight speeds,and rotor mounting angle errors.Finally,the feasibility of the rotor cross-tilt mounting angle is proved by analyzing the control derivatives of the flight dynamics model,the test data of a ground three Degree-of-Freedom(3DOF)platform,and the actual flight data of the prototype.The results show that a fixed rotor cross-tilt mounting angle can achieve ideal yaw control effectiveness,improving yaw angle tracking and hold ability,increasing endurance time,and achieving good yaw control performance with different payloads and forward speeds.展开更多
文摘A physiological state of＂normoxia＂obtains when tissue oxygen tension（pO_2）is sufficient to drive mitochondrial respiration throughout a volume of cells.Between 30-40%of the available oxygen is normally extracted from hemoglobin as it passes through neural tissue.
文摘Hardship The Double Take column looks at a single topic from an African and Chinese perspective.This month,we explore whether enduring hardship is still a necessary path to growth in a changing world.
文摘1 Originally published in 1993,To Live,a novel by Chinese author Yu Hua has since gained international recognition for its raw emotional depth and exploration of themes like fate,endurance and the essence of humanity.2 The novel follows the life of Xu Fugui,a once⁃wealthy landowner who lost his fortune through gambling(赌博).As his status shifted to that of a peasant,he witnessed the rapid changes of society.Despite enduring relentless hardship,Fugui survived,finding moments of comfort in small and everyday acts of perseverance.
基金supported by the National Natural Science Foundation of China(Grant No.NSFC11932013)National Key Research and Development Program of China(Grant No.2022YFB3805800).
文摘Background:Despite the wide use of compression garments to enhance athletic running performance,evidence supporting improvements has not been conclusive.This updated systematic review and meta-analysis of randomized controlled trials(RCTs)compared the effects of compression garment wearing with those of non-compression garment wearing(controls)during running on improving running performance.Methods:A comprehensive search was conducted in the electronic databases(Web of Science,EBSCOhost,PubMed,Embase,Scopus,and Cochrane)for RCTs comparing running performance between runners wearing compression garments and controls during running,from inception to September 2024.Independent reviewers screened studies,extracted data,appraised risk of bias(RoB 2)and certainty of evidence(Grading of Recommendations Assessments,Development and Evaluation(GRADE)).Primary outcomes were race time and time to exhaustion.Secondary outcomes covered running speed and race pace,submaximal oxygen uptake,tissue oxygenation,and soft tissue vibration.Randomeffects meta-analyses were conducted to generate pooled estimates,expressed in standardized mean difference(SMD).Subgroup differences of garment,race type,and contact surface were tested in moderator analyses.Results:The search yielded 51 eligible studies comprising 899 participants,of which 33 studies were available for meta-analysis of primary outcomes.Runners wearing compression garments during running showed no significant improvement in race time(SMD=-0.07,95%CI:-0.22 to 0.09;p=0.40)or time to exhaustion(SMD=0.04,95%CI:-0.20 to 0.29;p=0.72).Moderator analyses indicated no effects from garment type,race type,or surface.Secondary outcomes also showed no performance benefits,although compression garments significantly reduced soft tissue vibration(SMD=-0.43,95%CI:-0.70 to-0.15;p<0.01).Certainty of evidence was rated low to very low.Conclusion:Data synthesis of current RCTs offers no updated evidence favoring the support of wearing compression garments during running as a viable strategy for improving running and endurance performance among runners of varying performance levels and types of running races.
文摘Background:Sport climbing is becoming incredibly popular both in the general population and among athletes.No consensus exists regarding evidence-based sport-specific performance evaluation;therefore,this systematic review was aimed at analyzing determinants of sport climbing performance and evaluation methods by comparing climbers of different levels.Methods:PubMed,Scopus,and Web of Science were searched up to December 20,2022.Studies providing the self-reported climbing ability associated with different functional outcomes in groups of climbers of contiguous performance levels were eligible.Results:74 studies were finally included.Various methods have been proposed to evaluate determinants of sport climbing performance.Climbing-specific assessments were able to discriminate climbers of different levels when compared to general functional tests.Test validity resulted high for climbing-specific cardiorespiratory endurance as well as muscular-strength,-endurance,and-power;similarly,reliability was good except for cardiorespiratory endurance.Climbing-specific flexibility assessment resulted in high reliability but moderate validity,whereas balance showed low validity.Considerable conflicting evidence was found regarding anthropometric characteristics.Conclusion:The present analysis identified cardiorespiratory endurance as well as muscular-strength,-endurance,and-power as determinants of sport climbing performance.In contrast,balance,flexibility,and anthropometric characteristics seem to count less.This review also proposes an evidence-based Functional Sport Climbing test battery for asses sing performance determinants,which includes tests that have been identified to be valid,reliable,and feasible.While athletes and coaches should rely on evidence-based and standardized evaluation methods,researchers may design specific large-scale trials as a resource for providing additional,homogenous,and comparable data to improve scientific evidence and professionalism in this popular sport discipline.
文摘Rainbows-symbolizing peace,hope,promise and endurance(忍耐力)in hard times-are springing up in neighborhoods throughout Long Island in an effort to color the future road with optimism.The campaign,Rainbows over Nassau and Suffolk Counties and Beyond,started on March 21 and spread through a group.It's a campaign that encourages participants to make rainbows to display outside their homes,anywhere from their front windows and doors to lawns and sidewalks.It follows another similar project,Chalk Your Walk,which promotes writing hopeful messages in chalk on driveways and sidewalks.
基金supported by the Yayasan Universiti Teknologi PETRONAS(YUTP)under Cost Center 015LC0-485.
文摘Unmanned aerial vehicles(UAVs)technology is rapidly advancing,offering innovative solutions for various industries,including the critical task of oil and gas pipeline surveillance.However,the limited flight time of conventional UAVs presents a significant challenge to comprehensive and continuous monitoring,which is crucial for maintaining the integrity of pipeline infrastructure.This review paper evaluates methods for extending UAV flight endurance,focusing on their potential application in pipeline inspection.Through an extensive literature review,this study identifies the latest advancements in UAV technology,evaluates their effectiveness,and highlights the existing gaps in achieving prolonged flight operations.Advanced techniques,including artificial intelligence(AI),machine learning(ML),and deep learning(DL),are reviewed for their roles in pipeline monitoring.Notably,DL algorithms like You Only Look Once(YOLO)are explored for autonomous flight in UAV-based inspections,real-time defect detection,such as cracks,corrosion,and leaks,enhancing reliability and accuracy.A vital aspect of this research is the proposed deployment of a hybrid drone design combining lighter-than-air(LTA)and heavier-than-air(HTA)principles,achieving a balance of endurance and maneuverability.LTA vehicles utilize buoyancy to reduce energy consumption,thereby extending flight durations.The paper details the methodology for designing LTA vehicles,presenting an analysis of design parameters that align with the requirements for effective pipeline surveillance.The ongoing work is currently at Technology Readiness Level(TRL)4,where key components have been validated in laboratory conditions,with fabrication and flight testing planned for the next phase.Initial design analysis indicates that LTA configurations could offer significant advantages in flight endurance compared to traditional UAV designs.These findings lay the groundwork for future fabrication and testing phases,which will be critical in validating and assessing the proposed approach’s real-world applicability.By outlining the technical complexities and proposing specialized techniques tailored for pipeline monitoring,this paper provides a foundational framework for advancing UAV capabilities in the oil and gas sector.Researchers and industry practitioners can use this roadmap to further develop UAV-enabled surveillance solutions,aiming to improve the reliability,efficiency,and safety of pipeline monitoring.
文摘BACKGROUND In pediatric and adolescent athletes,there is a lack of understanding about the impact of factors such as race on the structural or cardiovascular adaptations in response to exercise which may unnecessarily disqualify athletes from the competitive sport.We hypothesized that race has an impact on cardiac adaptions in non-adult athletes.AIM To explore the racial disparity in electrocardiographic(ECG)and echocardiographic(ECHO)parameters in healthy adolescent athletes.METHODS A comprehensive electronic systematic literature search using MEDLINE database was performed from inception to September 20,2024.Inclusion criteria included randomized or observational cohort studies that recruited adolescent competitive athletes in any sport discipline and compared between the Black and White races with an age range of 12-18 years.RESULTS Of 723 records that were identified by the literature search,seven studies(n=5036)were included.The mean age was 13.0-18.0 years old with male predominance.Black athletes had significantly longer PR interval[mean difference(MD)=17.49 millisecond,95% CI:11.70-23.29]and shorter QRS complex duration(MD=-7.35 millisecond,95% CI:-9.17 to-5.53)and corrected QT interval(MD=-4.95 millisecond,95% CI:-7.69 to-2.22)than the White athletes.Black athletes were approximately four times more likely to have first-degree atrioventricular(AV)block,inverted T wave,ST-segment elevation,and left atrium(LA)enlargement than their White counterparts.In terms of ECHO parameters,Black athletes had significantly greater septal wall thickness(MD=0.85 mm,95% CI:0.62-1.07),posterior wall thickness(MD=1.07 mm,95% CI:0.36-1.78),relative wall thickness(MD=0.03,95%CI:0.001-0.06),maximal wall thickness(MD=1.05 mm,95%CI:0.28-1.83),and LA diameter(MD=1.64 mm,95%CI:0.16-3.12).CONCLUSION Race has an impact on the ECG and ECHO parameters that reflect cardiac adaptations in adolescent athletes.Black athletes tend to have an increased prevalence of distinct ECG changes such as first-degree AV block and T-wave inversions compared with their White counterparts.Despite having thicker septal and posterior walls,the overall prevalence of left ventricular hypertrophy did not differ between the races.
文摘Tennis,a popular sport in colleges and universities,is deeply loved by teachers and students.However,due to its high physical demands,technical difficulty,and other characteristics,it requires a high level of physical fitness.Compared to competitive tennis,although college tennis instruction may lack competitiveness and involve lower exercise intensity,it still necessitates regular physical training to enhance body coordination,balance,and agility.This can help students stay physically fit while avoiding injuries.This article explores the content of physical training in college tennis instruction,clarifies the important role of physical training,and summarizes a series of physical training pathways to provide reference support for physical training in college tennis instruction.
基金Supported by the Youth Doctor Support Project of the Education Department of Gansu Province,No.2024QB-100.
文摘BACKGROUND Lung cancer is one of the most common and deadly cancers worldwide.As the disease progresses and due to the side effects of treatment,patients’physical activity significantly decreases.AIM To systematically review and conduct a meta-analysis on the effects of exercise rehabilitation on the physical activity of lung cancer patients and determine the best implementation methods to provide clinical guidance.METHODS Literature was searched through multiple electronic databases.A random effects model was used to combine effect sizes through standardized mean difference(SMD).The Cochrane risk of bias tool was used to assess the quality of the lite-rature,sensitivity analysis was used to ensure the robustness of the results,and Egger’s test was used to detect publication bias and asymmetry.RESULTS A total of 11 studies involving 541 patients were included in this study.The phy-sical endurance,muscle function and cardiopulmonary function of non-small cell lung cancer(NSCLC)patients were evaluated.The overall effect size of the six-minute walk test(6MWT)was not statistically significant.However,subgroup analysis found that endurance significantly improved when exercise duration exceeded 0.5 hours(P≤0.05).In terms of muscle function,the overall effect size was SMD=0.619.Subgroup analysis showed that strength training,respiratory training,and cross-training(XT)significantly improved muscle function.Exercise rehabilitation significantly enhanced cardiopulmonary endurance(SMD=0.856,P=0.002),and the effect was better when the single exercise duration was more than 1 hour,age was over 65 years,and the intervention period was more than 3 months.CONCLUSION Exercise rehabilitation effectively improved muscle function in NSCLC patients,especially strength training,respiratory training,and cross-training.Cardiopulmonary function also showed improvement,particularly when exercise duration exceeded 1 hour,age was≥65 years,and the intervention period was more than 3 months.A single exercise duration of more than 0.5 hours can enhance patients’physical endurance.Appropriately increasing exercise duration and selecting suitable exercise forms can effectively improve the physical activity of NSCLC patients.
文摘On a summer morning in Boqiang Village,tucked beneath the emerald mountains of Fanshi County,Shanxi Province,the Ultra Trail Mount Wutai 2025 commenced with the sound of the starting pistol-an event that was much more than just a competition.As soon as the colourful smoke bombs lit up the sky,some 2,000 runners from China and abroad set off to reach one of the country’s most sacred Buddhist peaks.Over the past decade,this race has become a fixture on the global running calendar and a symbol of the growing popularity of endurance sports.
文摘This study proposes a method for calculating the probability distribution of structural responses at different intensities using the endurance time(ET)method.The results can be used to calculate the fragility curve of structural collapse.The ET method involves dynamic analysis of a structure under an intensifying record over time.While conventional ET methods can determine the median of the structural response,they lack the ability to calculate its dispersion.To address this limitation,the present study utilizes ET analysis and single-degree-of-freedom(SDOF)systems to develop a method that considers the record-to-record variability for calculating the probability distribution of structural response.The accuracy of this method is evaluated by comparing it with the incremental dynamic analysis(IDA)method using special moment frames.The results demonstrate that the proposed method achieves a reasonably accurate estimation of dispersion while significantly reducing the computational burden(by approximately 95%)compared to the IDA method.
文摘In the terraced fields in Honghe Hani and Yi Autonomous Prefecture,southwest China’s Yunnan Province,the morning mist drifts up from the valleys while the tiered ridges spread like the fingerprints of the earth.
基金supported by a Sara Borrell postdoctoral contract granted by Instituto de Salud Carlos III(CD21/00138).PLV,DB-G and AL are funded by the Spanish Ministry of Economy and Competitiveness and Fondos Feder(Alejandro Lucia,Grant No.PI18/00139)TP is funded by the Spanish Ministry of Economy and Competitiveness and Fondos Feder(Tomas Pinos,Grant No.PI22/00201).
文摘Background:This study aimed to determine the effect of different carbohydrate(CHO)doses on exercise capacity in patients with McArdle disease—the paradigm of“exercise intolerance”,characterized by complete muscle glycogen unavailability—and to determine whether higher exogenous glucose levels affect metabolic responses at the McArdle muscle cell(in vitro)level.Methods:Patients with McArdle disease(n=8)and healthy controls(n=9)underwent a 12-min submaximal cycling constant-load bout followed by a maximal ramp test 15 min after ingesting a non-caloric placebo.In a randomized,double-blinded,cross-over design,patients repeated the tests after consuming either 75 g or 150 g of CHO(glucose:fructose=2:1).Cardiorespiratory,biochemical,perceptual,and electromyographic(EMG)variables were assessed.Additionally,glucose uptake and lactate appearance were studied in vitro in wild-type and McArdle mouse myotubes cultured with increasing glucose concentrations(0.35,1.00,4.50,and 10.00 g/L).Results:Compared with controls,patients showed the“classical”second-wind phenomenon(after prior disproportionate tachycardia,myalgia,and excess electromyographic activity during submaximal exercise,all p<0.05)and an impaired endurance exercise capacity(-51%ventilatory threshold and55%peak power output,both p<0.001).Regardless of the CHO dose(p<0.05 for both doses compared with the placebo),CHO intake increased blood glucose and lactate levels,decreased fat oxidation rates,and attenuated the second wind in the patients.However,only the higher dose increased ventilatory threshold(+27%,p=0.010)and peak power output(+18%,p=0.007).In vitro analyses revealed no differences in lactate levels across glucose concentrations in wild-type myotubes,whereas a doseresponse effect was observed in McArdle myotubes.Conclusion:CHO intake exerts beneficial effects on exercise capacity in McArdle disease,a condition associated with total muscle glycogen unavailability.Some of these benefits are dose dependent.
基金This work was supported by the National Natural Science Foundation of China(Nos.62034006,92264201,and 91964105)the Natural Science Foundation of Shandong Province(Nos.ZR2020JQ28 and ZR2020KF016)the Program of Qilu Young Scholars of Shandong University.
文摘With the rapid development of machine learning,the demand for high-efficient computing becomes more and more urgent.To break the bottleneck of the traditional Von Neumann architecture,computing-in-memory(CIM)has attracted increasing attention in recent years.In this work,to provide a feasible CIM solution for the large-scale neural networks(NN)requiring continuous weight updating in online training,a flash-based computing-in-memory with high endurance(10^(9) cycles)and ultrafast programming speed is investigated.On the one hand,the proposed programming scheme of channel hot electron injection(CHEI)and hot hole injection(HHI)demonstrate high linearity,symmetric potentiation,and a depression process,which help to improve the training speed and accuracy.On the other hand,the low-damage programming scheme and memory window(MW)optimizations can suppress cell degradation effectively with improved computing accuracy.Even after 109 cycles,the leakage current(I_(off))of cells remains sub-10pA,ensuring the large-scale computing ability of memory.Further characterizations are done on read disturb to demonstrate its robust reliabilities.By processing CIFAR-10 tasks,it is evident that~90%accuracy can be achieved after 109 cycles in both ResNet50 and VGG16 NN.Our results suggest that flash-based CIM has great potential to overcome the limitations of traditional Von Neumann architectures and enable high-performance NN online training,which pave the way for further development of artificial intelligence(AI)accelerators.
基金co-supported by the National Natural Science Foundation of China(Nos.12202406,11672128)。
文摘Manned multi-rotor electric Vertical Takeoff and Landing(eVTOL)aircraft is prone to actuator saturation due to its weak yaw control efficiency.To address this inherent problem,a rotor cross-tilt configuration is applied in this paper,with an optimization method proposed to improve the overall control efficiency of the vehicle.First,a flight dynamics model of a 500-kg manned multi-rotor eVTOL aircraft is established.The accuracy of the co-axial rotor model is verified using a single arm test bench,and the accuracy of the flight dynamics model is verified by the flight test data.Then,an optimization method is designed based on the flight dynamics model to calculate an optimal rotor cross-tilt mounting angle,which not only improves the yaw control efficiency,but also basically maintains the efficiency of other control channels.The ideal rotor cross-tilt mounting angle for the prototype is determined by comprehensively considering the optimal results with different payloads,forward flight speeds,and rotor mounting angle errors.Finally,the feasibility of the rotor cross-tilt mounting angle is proved by analyzing the control derivatives of the flight dynamics model,the test data of a ground three Degree-of-Freedom(3DOF)platform,and the actual flight data of the prototype.The results show that a fixed rotor cross-tilt mounting angle can achieve ideal yaw control effectiveness,improving yaw angle tracking and hold ability,increasing endurance time,and achieving good yaw control performance with different payloads and forward speeds.
