[Objective] The aim of this study was to investigate the storage durability of a new line of endurable storage hybrid rice Chucangyou No.1 selected by endurable storage genes of Yunhui 290.[Method] Agronomic character...[Objective] The aim of this study was to investigate the storage durability of a new line of endurable storage hybrid rice Chucangyou No.1 selected by endurable storage genes of Yunhui 290.[Method] Agronomic characters of the new line and the control II you 838 and Shanyou 63 were comparatively studied,and storage durability of the new line and indica,japonica or hybrid rice were also comparatively analyzed by the accelerated ageing test.[Result] Agronomic characters of the new line were excellent,and germination rate in the artificial accelerated ageing test was significantly higher than those in other materials.[Conclusion] Chucangyou No.1 has the better storage durability,which can be used in large scale of extention.展开更多
The development of the cotton fiber is very sensitive to temperature variation, and high temperature stress often causes reduced fiber yield and fiber quality. Short-term high temperature stress often occurs during co...The development of the cotton fiber is very sensitive to temperature variation, and high temperature stress often causes reduced fiber yield and fiber quality. Short-term high temperature stress often occurs during cotton production, but little is known about the specific timing and duration of stress that affects fiber development. To make this clear, pot experiments were carried in 2014 and 2015 in a climate chamber using cotton cultivars HY370WR（less sensitive variety） and Sumian 15（heat sensitive variety）, which present different temperature sensitivities. Changes of the most important fiber quality indices（i.e., fiber length, fiber strength and marcironaire） and three very important fiber development components（i.e., cellulose, sucrose and callose） were analyzed to define the time window and critical duration to the high temperature stress at 34°C（max38°C/min30°C）. When developing bolls were subjected to 5 days of high temperature stress at different days post-anthesis（DPA）, the changes（Δ%） of fiber length, strength and micronire, as a function of imposed time followed square polynomial eq. as y=a＋bx＋cx^2, and the time around 15 DPA was the most sensitive period for fiber quality development in response to heat stress. When 15 DPA bolls were heat-stressed for different durations（2, 3, 4, 5, 6, 7 days）, the changes（Δ%） of fiber length, strength and micronire, as a function of stress duration followed logistic equations y=A_1-A_2/1＋（x/x_0）~p＋A_2. Referred to that 5, 10 and 15% are usually used as criteria to decide whether techniques are effective or changes are significant in crop culture practice and reguard to the fiber quality indices change range, we suggested that 5% changes of the major fiber quality indices（fiber length, fiber strength and micronaire） and 10% changes of fiber development components（cellulose, sucrose and callose） could be taken as criteria to judge whether fiber development and fiber quality have been significantly affected by high temperature stress. The key time window for cotton fiber development in response to the high temperature stress was 13–19 DPA, and the critical duration was about 5 days.展开更多
Background:Cupping therapy(CT),an ancient practice revived in modern sports medicine,offers potential benefits for athlete recovery and performance.Distinctions between wet CT(WCT)and dry CT(DCT)in sports science focu...Background:Cupping therapy(CT),an ancient practice revived in modern sports medicine,offers potential benefits for athlete recovery and performance.Distinctions between wet CT(WCT)and dry CT(DCT)in sports science focus on their effects on recovery metrics,particularly how they influence sleep quality,perceived wellness,and athletic performance.Despite anecdotal evidence of its efficacy,rigorous comparative studies are scarce.Objective:This study aimed to evaluates and compare the effects of WCT and DCT on endurance,perceived wellness,exertion levels,and sleep quality among young,active males,addressing the gap in the literature regarding CT's efficacy in sports performance and recovery.Methods:Thirty-two amateur runners were randomly divided into two groups:one followed WCT sessions and the other followed DCT sessions.The study assessed the interventions'impacts on endurance performance(Yo-Yo intermittent recovery test),sleep quality(Pittsburgh Sleep Quality Index),and perceived exertion(Borg CR10 Scale).Heart rate was measured using a Polar H10 sensor to gauge physiological responses during physical tests.Results:Significant improvements were observed in the WCT group for sleep latency(%change=-82.31%;interaction group×time p=0.006;Cohen's d=0.74)and sleep disturbance(%change=-68.70%;interaction group×time p<0.001;Cohen's d=1.09),suggesting enhanced sleep quality(global score;%change=-52.81;interaction group×time p=0.004;Cohen's d=0.77).However,no significant differences were found in direct performance metrics(distance,maximal heart rate,maximal oxygen uptake)between WCT and DCT groups.These findings highlight WCT's potential as a recovery aid,particularly through improved sleep,without directly influencing endurance performance outcomes.Conclusion:WCT may serve as an effective ergogenic aid for athletes by potentially improving sleep quality and reducing perceived exertion,thus contributing indirectly to performance through enhanced recovery.展开更多
Background Regular physical training induces adaptive effects across multiple organ systems,highlighting the existence of inter-organ communication networks.However,the molecular mechanisms underlying both exercise-in...Background Regular physical training induces adaptive effects across multiple organ systems,highlighting the existence of inter-organ communication networks.However,the molecular mechanisms underlying both exercise-induced adaptations and organ-to-organ signaling are not fully characterized.Circulating extracellular vesicles(EVs),including exosomes,carry molecules like microRNAs(miRNAs)that may mediate tissue crosstalk.This study aimed to identify specific exercise training-responsive miRNAs that affect skeletal muscle function.Methods miRNA expression profiles of serum-derived EVs were analyzed in healthy young individuals before and after 3 weeks endurance exercise training.Exercise training-responsive miRNAs were then validated for a functional role in cellular metabolic processes in human myotubes.Results We identified several exercise training-responsive miRNAs within exosome-rich EVs in serum,including miR-136-3p.In human myotubes,miR-136-3p enhanced glucose uptake and targeted the nardilysin convertase(NRDC)gene.Transfection of miR-136-3p or silencing of NRDC induced a shift towards glycolytic metabolism in mitochondria and modulated gene expressions related to myogenesis.Pancreatic islets were identified as a potential source of miR-136-3p based on in silico analysis of gene expression and a molecular analysis of conditioned media from isolated pancreatic islets.Conclusion MiR-136-3p is an endurance training-responsive molecular transducer that modulates glucose metabolism and cellular proliferation in myocytes.Associated with EVs,extracellular miR-136-3p may serve as a molecular messenger to communicate islet–skeletal muscle crosstalk after exercise.Extracellular miR-136-3p may serve as a molecular messenger to communicate islet–skeletal muscle crosstalk.Our results highlight a miRNA-mediated mechanism that participates in inter-organ communication to fine tune the metabolic adaptations to exercise.展开更多
Deduplication has been commonly used in both enterprise storage systems and cloud storage. To overcome the performance challenge for the selective restore operations of deduplication systems, solid-state-drive-based ...Deduplication has been commonly used in both enterprise storage systems and cloud storage. To overcome the performance challenge for the selective restore operations of deduplication systems, solid-state-drive-based （i.e., SSD-based） re^d cache cm, be deployed for speeding up by caching popular restore contents dynamically. Unfortunately, frequent data updates induced by classical cache schemes （e.g., LRU and LFU） significantly shorten SSDs＇ lifetime while slowing down I/O processes in SSDs. To address this problem, we propose a new solution -- LOP-Cache to greatly improve tile write durability of SSDs as well as I/O performance by enlarging the proportion of long-term popular （LOP） data among data written into SSD-based cache. LOP-Cache keeps LOP data in the SSD cache for a long time period to decrease the number of cache replacements. Furthermore, it prevents unpopular or unnecessary data in deduplication containers from being written into the SSD cache. We implemented LOP-Cache in a prototype deduplication system to evaluate its pertbrmance. Our experimental results indicate that LOP-Cache shortens the latency of selective restore by an average of 37.3% at the cost of a small SSD-based cache with only 5.56% capacity of the deduplicated data. Importantly, LOP-Cache improves SSDs＇ lifetime by a factor of 9.77. The evidence shows that LOP-Cache offers a cost-efficient SSD-based read cache solution to boost performance of selective restore for deduplication systems.展开更多
Solid-state drives (SSDs)have been widely used as caching tier for disk-based RAID systems to speed up dataintensive applications.However,traditional cache schemes fail to effectively boost the parity-based RAID stora...Solid-state drives (SSDs)have been widely used as caching tier for disk-based RAID systems to speed up dataintensive applications.However,traditional cache schemes fail to effectively boost the parity-based RAID storage sys- tems (e.g.,RAID-5/6),which have poor random write performance due to the small-write problem.What's worse,intensive cache writes can wear out the SSD quickly,which causes performance degradation and cost increment.In this article,we present the design and implementation of KDD, an efficient SSD-based caching system which Keeps Data and Deltas in SSD.When write requests hit in the cache, KDD dispatches the data to the RAID storage without updating the parity blocks to mitigate the small write penalty, and compactly stores the compressed deltas in SSD to reduce the cache write traffic while guaranteeing reliability in case of disk failures.In addition,KDD organizes the metadata partition on SSD as a circular log to make the cache persistent with low overhead.We evaluate the performance of KDD via both simulations and prototype implementations.Experimental results show that KDD effectively reduces the small write penalty while extending the lifetime of the SSD-based cache by up to 6.85 times.展开更多
Unmanned aerial vehicles(UAVs)technology is rapidly advancing,offering innovative solutions for various industries,including the critical task of oil and gas pipeline surveillance.However,the limited flight time of co...Unmanned aerial vehicles(UAVs)technology is rapidly advancing,offering innovative solutions for various industries,including the critical task of oil and gas pipeline surveillance.However,the limited flight time of conventional UAVs presents a significant challenge to comprehensive and continuous monitoring,which is crucial for maintaining the integrity of pipeline infrastructure.This review paper evaluates methods for extending UAV flight endurance,focusing on their potential application in pipeline inspection.Through an extensive literature review,this study identifies the latest advancements in UAV technology,evaluates their effectiveness,and highlights the existing gaps in achieving prolonged flight operations.Advanced techniques,including artificial intelligence(AI),machine learning(ML),and deep learning(DL),are reviewed for their roles in pipeline monitoring.Notably,DL algorithms like You Only Look Once(YOLO)are explored for autonomous flight in UAV-based inspections,real-time defect detection,such as cracks,corrosion,and leaks,enhancing reliability and accuracy.A vital aspect of this research is the proposed deployment of a hybrid drone design combining lighter-than-air(LTA)and heavier-than-air(HTA)principles,achieving a balance of endurance and maneuverability.LTA vehicles utilize buoyancy to reduce energy consumption,thereby extending flight durations.The paper details the methodology for designing LTA vehicles,presenting an analysis of design parameters that align with the requirements for effective pipeline surveillance.The ongoing work is currently at Technology Readiness Level(TRL)4,where key components have been validated in laboratory conditions,with fabrication and flight testing planned for the next phase.Initial design analysis indicates that LTA configurations could offer significant advantages in flight endurance compared to traditional UAV designs.These findings lay the groundwork for future fabrication and testing phases,which will be critical in validating and assessing the proposed approach’s real-world applicability.By outlining the technical complexities and proposing specialized techniques tailored for pipeline monitoring,this paper provides a foundational framework for advancing UAV capabilities in the oil and gas sector.Researchers and industry practitioners can use this roadmap to further develop UAV-enabled surveillance solutions,aiming to improve the reliability,efficiency,and safety of pipeline monitoring.展开更多
BACKGROUND Lung cancer is one of the most common and deadly cancers worldwide.As the disease progresses and due to the side effects of treatment,patients’physical activity significantly decreases.AIM To systematicall...BACKGROUND Lung cancer is one of the most common and deadly cancers worldwide.As the disease progresses and due to the side effects of treatment,patients’physical activity significantly decreases.AIM To systematically review and conduct a meta-analysis on the effects of exercise rehabilitation on the physical activity of lung cancer patients and determine the best implementation methods to provide clinical guidance.METHODS Literature was searched through multiple electronic databases.A random effects model was used to combine effect sizes through standardized mean difference(SMD).The Cochrane risk of bias tool was used to assess the quality of the lite-rature,sensitivity analysis was used to ensure the robustness of the results,and Egger’s test was used to detect publication bias and asymmetry.RESULTS A total of 11 studies involving 541 patients were included in this study.The phy-sical endurance,muscle function and cardiopulmonary function of non-small cell lung cancer(NSCLC)patients were evaluated.The overall effect size of the six-minute walk test(6MWT)was not statistically significant.However,subgroup analysis found that endurance significantly improved when exercise duration exceeded 0.5 hours(P≤0.05).In terms of muscle function,the overall effect size was SMD=0.619.Subgroup analysis showed that strength training,respiratory training,and cross-training(XT)significantly improved muscle function.Exercise rehabilitation significantly enhanced cardiopulmonary endurance(SMD=0.856,P=0.002),and the effect was better when the single exercise duration was more than 1 hour,age was over 65 years,and the intervention period was more than 3 months.CONCLUSION Exercise rehabilitation effectively improved muscle function in NSCLC patients,especially strength training,respiratory training,and cross-training.Cardiopulmonary function also showed improvement,particularly when exercise duration exceeded 1 hour,age was≥65 years,and the intervention period was more than 3 months.A single exercise duration of more than 0.5 hours can enhance patients’physical endurance.Appropriately increasing exercise duration and selecting suitable exercise forms can effectively improve the physical activity of NSCLC patients.展开更多
Hardship The Double Take column looks at a single topic from an African and Chinese perspective.This month,we explore whether enduring hardship is still a necessary path to growth in a changing world.
1 Originally published in 1993,To Live,a novel by Chinese author Yu Hua has since gained international recognition for its raw emotional depth and exploration of themes like fate,endurance and the essence of humanity....1 Originally published in 1993,To Live,a novel by Chinese author Yu Hua has since gained international recognition for its raw emotional depth and exploration of themes like fate,endurance and the essence of humanity.2 The novel follows the life of Xu Fugui,a once⁃wealthy landowner who lost his fortune through gambling(赌博).As his status shifted to that of a peasant,he witnessed the rapid changes of society.Despite enduring relentless hardship,Fugui survived,finding moments of comfort in small and everyday acts of perseverance.展开更多
Background:Despite the wide use of compression garments to enhance athletic running performance,evidence supporting improvements has not been conclusive.This updated systematic review and meta-analysis of randomized c...Background:Despite the wide use of compression garments to enhance athletic running performance,evidence supporting improvements has not been conclusive.This updated systematic review and meta-analysis of randomized controlled trials(RCTs)compared the effects of compression garment wearing with those of non-compression garment wearing(controls)during running on improving running performance.Methods:A comprehensive search was conducted in the electronic databases(Web of Science,EBSCOhost,PubMed,Embase,Scopus,and Cochrane)for RCTs comparing running performance between runners wearing compression garments and controls during running,from inception to September 2024.Independent reviewers screened studies,extracted data,appraised risk of bias(RoB 2)and certainty of evidence(Grading of Recommendations Assessments,Development and Evaluation(GRADE)).Primary outcomes were race time and time to exhaustion.Secondary outcomes covered running speed and race pace,submaximal oxygen uptake,tissue oxygenation,and soft tissue vibration.Randomeffects meta-analyses were conducted to generate pooled estimates,expressed in standardized mean difference(SMD).Subgroup differences of garment,race type,and contact surface were tested in moderator analyses.Results:The search yielded 51 eligible studies comprising 899 participants,of which 33 studies were available for meta-analysis of primary outcomes.Runners wearing compression garments during running showed no significant improvement in race time(SMD=-0.07,95%CI:-0.22 to 0.09;p=0.40)or time to exhaustion(SMD=0.04,95%CI:-0.20 to 0.29;p=0.72).Moderator analyses indicated no effects from garment type,race type,or surface.Secondary outcomes also showed no performance benefits,although compression garments significantly reduced soft tissue vibration(SMD=-0.43,95%CI:-0.70 to-0.15;p<0.01).Certainty of evidence was rated low to very low.Conclusion:Data synthesis of current RCTs offers no updated evidence favoring the support of wearing compression garments during running as a viable strategy for improving running and endurance performance among runners of varying performance levels and types of running races.展开更多
Background:Sport climbing is becoming incredibly popular both in the general population and among athletes.No consensus exists regarding evidence-based sport-specific performance evaluation;therefore,this systematic r...Background:Sport climbing is becoming incredibly popular both in the general population and among athletes.No consensus exists regarding evidence-based sport-specific performance evaluation;therefore,this systematic review was aimed at analyzing determinants of sport climbing performance and evaluation methods by comparing climbers of different levels.Methods:PubMed,Scopus,and Web of Science were searched up to December 20,2022.Studies providing the self-reported climbing ability associated with different functional outcomes in groups of climbers of contiguous performance levels were eligible.Results:74 studies were finally included.Various methods have been proposed to evaluate determinants of sport climbing performance.Climbing-specific assessments were able to discriminate climbers of different levels when compared to general functional tests.Test validity resulted high for climbing-specific cardiorespiratory endurance as well as muscular-strength,-endurance,and-power;similarly,reliability was good except for cardiorespiratory endurance.Climbing-specific flexibility assessment resulted in high reliability but moderate validity,whereas balance showed low validity.Considerable conflicting evidence was found regarding anthropometric characteristics.Conclusion:The present analysis identified cardiorespiratory endurance as well as muscular-strength,-endurance,and-power as determinants of sport climbing performance.In contrast,balance,flexibility,and anthropometric characteristics seem to count less.This review also proposes an evidence-based Functional Sport Climbing test battery for asses sing performance determinants,which includes tests that have been identified to be valid,reliable,and feasible.While athletes and coaches should rely on evidence-based and standardized evaluation methods,researchers may design specific large-scale trials as a resource for providing additional,homogenous,and comparable data to improve scientific evidence and professionalism in this popular sport discipline.展开更多
Rainbows-symbolizing peace,hope,promise and endurance(忍耐力)in hard times-are springing up in neighborhoods throughout Long Island in an effort to color the future road with optimism.The campaign,Rainbows over Nassau...Rainbows-symbolizing peace,hope,promise and endurance(忍耐力)in hard times-are springing up in neighborhoods throughout Long Island in an effort to color the future road with optimism.The campaign,Rainbows over Nassau and Suffolk Counties and Beyond,started on March 21 and spread through a group.It's a campaign that encourages participants to make rainbows to display outside their homes,anywhere from their front windows and doors to lawns and sidewalks.It follows another similar project,Chalk Your Walk,which promotes writing hopeful messages in chalk on driveways and sidewalks.展开更多
Background:Surf skateboards have grown in popularity among young people in recent years.However,no research studies have analyzed the effect of surf skateboarding on physical fitness.Objective:The purpose of this stud...Background:Surf skateboards have grown in popularity among young people in recent years.However,no research studies have analyzed the effect of surf skateboarding on physical fitness.Objective:The purpose of this study was to determine the effects of 8-week surf skateboard training on physical fitness in young adults.Methods:Twenty-two young people,ages 18–24 years were randomly assigned into two groups:a control(CON;n=11)and surf skateboarding(SSK;n=11)group.The surf skateboard training group received an eight-week intervention consisting of three 60-minute(min)sessions per week,while the control group continued with their normal daily lives.Physical fitness was assessed before and after the intervention through a battery of tests that included body composition,cardiorespiratory fitness,muscular strength and endurance,flexibility,and balance.Results:The results showed that the SSK group demonstrated significant(p<0.05)improvements in maximum voluntary ventilation,back and leg strength,lower body muscular endurance by the sit-to-stand tests,and balance in all direction compared with the pre-test and the CON group.In addition,the SSK group showed significantly(p<0.05)decreased body weight,body mass index,percent body fat,and resting heart rate,while increased maximum oxygen consumption,pulmonary function,respiratory muscle strength,upper body muscular endurance by the sit-up test and flexibility compared with the pre-test.Conclusion:The findings suggest that surf skateboard training have an effective physical activity intervention to improve body composition,cardiorespiratory fitness,muscular strength and endurance,flexibility,and balance in young people.展开更多
BACKGROUND In pediatric and adolescent athletes,there is a lack of understanding about the impact of factors such as race on the structural or cardiovascular adaptations in response to exercise which may unnecessarily...BACKGROUND In pediatric and adolescent athletes,there is a lack of understanding about the impact of factors such as race on the structural or cardiovascular adaptations in response to exercise which may unnecessarily disqualify athletes from the competitive sport.We hypothesized that race has an impact on cardiac adaptions in non-adult athletes.AIM To explore the racial disparity in electrocardiographic(ECG)and echocardiographic(ECHO)parameters in healthy adolescent athletes.METHODS A comprehensive electronic systematic literature search using MEDLINE database was performed from inception to September 20,2024.Inclusion criteria included randomized or observational cohort studies that recruited adolescent competitive athletes in any sport discipline and compared between the Black and White races with an age range of 12-18 years.RESULTS Of 723 records that were identified by the literature search,seven studies(n=5036)were included.The mean age was 13.0-18.0 years old with male predominance.Black athletes had significantly longer PR interval[mean difference(MD)=17.49 millisecond,95% CI:11.70-23.29]and shorter QRS complex duration(MD=-7.35 millisecond,95% CI:-9.17 to-5.53)and corrected QT interval(MD=-4.95 millisecond,95% CI:-7.69 to-2.22)than the White athletes.Black athletes were approximately four times more likely to have first-degree atrioventricular(AV)block,inverted T wave,ST-segment elevation,and left atrium(LA)enlargement than their White counterparts.In terms of ECHO parameters,Black athletes had significantly greater septal wall thickness(MD=0.85 mm,95% CI:0.62-1.07),posterior wall thickness(MD=1.07 mm,95% CI:0.36-1.78),relative wall thickness(MD=0.03,95%CI:0.001-0.06),maximal wall thickness(MD=1.05 mm,95%CI:0.28-1.83),and LA diameter(MD=1.64 mm,95%CI:0.16-3.12).CONCLUSION Race has an impact on the ECG and ECHO parameters that reflect cardiac adaptations in adolescent athletes.Black athletes tend to have an increased prevalence of distinct ECG changes such as first-degree AV block and T-wave inversions compared with their White counterparts.Despite having thicker septal and posterior walls,the overall prevalence of left ventricular hypertrophy did not differ between the races.展开更多
Background:Habitual physical activity is known to support cardiovascular health.However,when intensive exercise is performed for long durations,it can negatively affect the cardiovascular system.We evaluated the exerc...Background:Habitual physical activity is known to support cardiovascular health.However,when intensive exercise is performed for long durations,it can negatively affect the cardiovascular system.We evaluated the exercise-induced physiological responses of cardiac markers in male marathon runners based on basal plasma trimethylamine-N-oxide(TMAO)levels,a metabolite related to major adverse cardiovascular events.Methods:Blood samples from 28 marathon runners were collected two weeks before the marathon run(baseline),after finishing the race(post-marathon),and two weeks after the race(2 weeks post-marathon).Serum cardiac troponin I(c Tn I),endothelin-1(ET-1),galectin-3,pentraxin-3,human growth differentiation factor 15,and neopterin were determined by the enzyme immunoassay method.Plasma trimethylamine(TMA)and TMAO were measured by the ultra-high-performance liquid chromatography-mass spectrometry method.Results:Running a marathon increased levels of circulating biomarkers.A greater post-marathon elevation of cTn I and ET-1 was associated with baseline plasma TMAO levels(R=0.400,p=0.035 and R=0.476,p=0.012,respectively).Moreover,we observed an increase in post-marathon TMA levels.Conclusion:Greater post-marathon elevation of cTn I and ET-1 was associated with higher baseline plasma TMAO levels.Therefore,TMAO could potentially serve as a new marker in assessing the response of cardiovascular stress biomarkers to marathon running.展开更多
Tennis,a popular sport in colleges and universities,is deeply loved by teachers and students.However,due to its high physical demands,technical difficulty,and other characteristics,it requires a high level of physical...Tennis,a popular sport in colleges and universities,is deeply loved by teachers and students.However,due to its high physical demands,technical difficulty,and other characteristics,it requires a high level of physical fitness.Compared to competitive tennis,although college tennis instruction may lack competitiveness and involve lower exercise intensity,it still necessitates regular physical training to enhance body coordination,balance,and agility.This can help students stay physically fit while avoiding injuries.This article explores the content of physical training in college tennis instruction,clarifies the important role of physical training,and summarizes a series of physical training pathways to provide reference support for physical training in college tennis instruction.展开更多
Along with NOR flash cell scaling down,dielectric burnout has gradually become one of the most important factors which affects product reliability,especially for high dropout voltage films.In this study,we demonstrate...Along with NOR flash cell scaling down,dielectric burnout has gradually become one of the most important factors which affects product reliability,especially for high dropout voltage films.In this study,we demonstrate a reliability-enhanced NOR flash cell in 50 nm node technology through structural optimization of floating gate(FG)dimensions and active area profile.By synergistically increasing FG thickness,reducing FG width,and tuning cell-open depth,the control gate-to-active area corner distance expands by 22%,suppressing peak electric fields by 29%vertically and 18%horizontally.This structural innovation achieves:(1)100×reduction in early-cycle burnout failures,(2)7.38×time dependent dielectric breakdown lifetime improve-ment,while maintaining data retention and accelerating programming/erasing speeds by 15.4%/7.3%.The enhanced reliability enables 97.5%reduction in Fowler−Nordheim stress time during characterization program testing,providing a cost-effective solution for automotive-grade flash memories.展开更多
Before you can tie your shoelaces for one of the worlds most remote races,you must first navigate through wild seas,endure(忍受)freezing temperatures and go on a journey that tests more than just your physical enduran...Before you can tie your shoelaces for one of the worlds most remote races,you must first navigate through wild seas,endure(忍受)freezing temperatures and go on a journey that tests more than just your physical endurance.This is no ordinary race;it requires thorough preparation and a strong will.展开更多
2025年6月5日,米其林宣布,正在推出全新Pilot Sport Endurance 2026系列轮胎,该系列专为超跑设计,将在克莱蒙费朗的卡塔鲁工厂生产。米其林表示,这款光面轮胎系列是该集团在可持续发展承诺中的重要进步,其目标是在轮胎成分中融入50%的...2025年6月5日,米其林宣布,正在推出全新Pilot Sport Endurance 2026系列轮胎,该系列专为超跑设计,将在克莱蒙费朗的卡塔鲁工厂生产。米其林表示,这款光面轮胎系列是该集团在可持续发展承诺中的重要进步,其目标是在轮胎成分中融入50%的可持续材料(可再生材料和回收材料)。展开更多
基金Support by National Key Technology R&D Program(2006BAD01A01-5)Science and Technological Fund of Anhui Province for Outstanding Youth(08040106802)~~
文摘[Objective] The aim of this study was to investigate the storage durability of a new line of endurable storage hybrid rice Chucangyou No.1 selected by endurable storage genes of Yunhui 290.[Method] Agronomic characters of the new line and the control II you 838 and Shanyou 63 were comparatively studied,and storage durability of the new line and indica,japonica or hybrid rice were also comparatively analyzed by the accelerated ageing test.[Result] Agronomic characters of the new line were excellent,and germination rate in the artificial accelerated ageing test was significantly higher than those in other materials.[Conclusion] Chucangyou No.1 has the better storage durability,which can be used in large scale of extention.
基金funded by the National Natural Science Foundation of China(31271654,31471444)the Natural Science Foundation of Jiangsu Province,China(BK20131318)
文摘The development of the cotton fiber is very sensitive to temperature variation, and high temperature stress often causes reduced fiber yield and fiber quality. Short-term high temperature stress often occurs during cotton production, but little is known about the specific timing and duration of stress that affects fiber development. To make this clear, pot experiments were carried in 2014 and 2015 in a climate chamber using cotton cultivars HY370WR（less sensitive variety） and Sumian 15（heat sensitive variety）, which present different temperature sensitivities. Changes of the most important fiber quality indices（i.e., fiber length, fiber strength and marcironaire） and three very important fiber development components（i.e., cellulose, sucrose and callose） were analyzed to define the time window and critical duration to the high temperature stress at 34°C（max38°C/min30°C）. When developing bolls were subjected to 5 days of high temperature stress at different days post-anthesis（DPA）, the changes（Δ%） of fiber length, strength and micronire, as a function of imposed time followed square polynomial eq. as y=a＋bx＋cx^2, and the time around 15 DPA was the most sensitive period for fiber quality development in response to heat stress. When 15 DPA bolls were heat-stressed for different durations（2, 3, 4, 5, 6, 7 days）, the changes（Δ%） of fiber length, strength and micronire, as a function of stress duration followed logistic equations y=A_1-A_2/1＋（x/x_0）~p＋A_2. Referred to that 5, 10 and 15% are usually used as criteria to decide whether techniques are effective or changes are significant in crop culture practice and reguard to the fiber quality indices change range, we suggested that 5% changes of the major fiber quality indices（fiber length, fiber strength and micronaire） and 10% changes of fiber development components（cellulose, sucrose and callose） could be taken as criteria to judge whether fiber development and fiber quality have been significantly affected by high temperature stress. The key time window for cotton fiber development in response to the high temperature stress was 13–19 DPA, and the critical duration was about 5 days.
文摘Background:Cupping therapy(CT),an ancient practice revived in modern sports medicine,offers potential benefits for athlete recovery and performance.Distinctions between wet CT(WCT)and dry CT(DCT)in sports science focus on their effects on recovery metrics,particularly how they influence sleep quality,perceived wellness,and athletic performance.Despite anecdotal evidence of its efficacy,rigorous comparative studies are scarce.Objective:This study aimed to evaluates and compare the effects of WCT and DCT on endurance,perceived wellness,exertion levels,and sleep quality among young,active males,addressing the gap in the literature regarding CT's efficacy in sports performance and recovery.Methods:Thirty-two amateur runners were randomly divided into two groups:one followed WCT sessions and the other followed DCT sessions.The study assessed the interventions'impacts on endurance performance(Yo-Yo intermittent recovery test),sleep quality(Pittsburgh Sleep Quality Index),and perceived exertion(Borg CR10 Scale).Heart rate was measured using a Polar H10 sensor to gauge physiological responses during physical tests.Results:Significant improvements were observed in the WCT group for sleep latency(%change=-82.31%;interaction group×time p=0.006;Cohen's d=0.74)and sleep disturbance(%change=-68.70%;interaction group×time p<0.001;Cohen's d=1.09),suggesting enhanced sleep quality(global score;%change=-52.81;interaction group×time p=0.004;Cohen's d=0.77).However,no significant differences were found in direct performance metrics(distance,maximal heart rate,maximal oxygen uptake)between WCT and DCT groups.These findings highlight WCT's potential as a recovery aid,particularly through improved sleep,without directly influencing endurance performance outcomes.Conclusion:WCT may serve as an effective ergogenic aid for athletes by potentially improving sleep quality and reducing perceived exertion,thus contributing indirectly to performance through enhanced recovery.
基金supported by grants from the Knut and Alice Wallenberg foundation(P-OB,JRZ,and AK)the Swedish Research Council(JRZ and AK),Centrum för idrottsforskning(AK and JRZ)+7 种基金the NovoNordisk Foundation Metabolic Stress Associated Molecules(MSAM)consortium NNF15SA0018346 and Metabolite-related Inflammation and Disease(MeRIAD)consortium Grant number 0064142(AK)the Swedish Diabetes Foundation(AK and JRZ)the European Foundation for the Study of Diabetes(JRZ and AK)the Region Stockholm(ALF project)(JRZ and KC)the Strategic Research Program in Diabetes at Karolinska Institutet(JRZ and AK)supported by the Strategic Research Programme in Diabetes(SRP Diabetes)for use of the Seahorse flux analyzer.Human islets were made possible through the Juvenile Diabetes Research Foundation(JDRF)award 31-2008-416(European Coordinating Infrastructure for Islet Transplantation(ECIT),Islet for Basic Research program)AK holds a Distinguished Investigator Grant within Endocrinology and Metabolism from the Novo Nordisk Foundation(NNF24OC0088739)JRZ received the 2024 European Association for the Study of Diabetes(ESAD)-Novo Nordisk Foundation Diabetes Prize for Excellence(NNF24SA0092609).
文摘Background Regular physical training induces adaptive effects across multiple organ systems,highlighting the existence of inter-organ communication networks.However,the molecular mechanisms underlying both exercise-induced adaptations and organ-to-organ signaling are not fully characterized.Circulating extracellular vesicles(EVs),including exosomes,carry molecules like microRNAs(miRNAs)that may mediate tissue crosstalk.This study aimed to identify specific exercise training-responsive miRNAs that affect skeletal muscle function.Methods miRNA expression profiles of serum-derived EVs were analyzed in healthy young individuals before and after 3 weeks endurance exercise training.Exercise training-responsive miRNAs were then validated for a functional role in cellular metabolic processes in human myotubes.Results We identified several exercise training-responsive miRNAs within exosome-rich EVs in serum,including miR-136-3p.In human myotubes,miR-136-3p enhanced glucose uptake and targeted the nardilysin convertase(NRDC)gene.Transfection of miR-136-3p or silencing of NRDC induced a shift towards glycolytic metabolism in mitochondria and modulated gene expressions related to myogenesis.Pancreatic islets were identified as a potential source of miR-136-3p based on in silico analysis of gene expression and a molecular analysis of conditioned media from isolated pancreatic islets.Conclusion MiR-136-3p is an endurance training-responsive molecular transducer that modulates glucose metabolism and cellular proliferation in myocytes.Associated with EVs,extracellular miR-136-3p may serve as a molecular messenger to communicate islet–skeletal muscle crosstalk after exercise.Extracellular miR-136-3p may serve as a molecular messenger to communicate islet–skeletal muscle crosstalk.Our results highlight a miRNA-mediated mechanism that participates in inter-organ communication to fine tune the metabolic adaptations to exercise.
基金This work is supported by the Natural Science Foundation of Beijing under Grant No. 4172031, the Pundamental Research FSmds for the Central Universities of China, and the Research Funds of Renmin University of China under Grant No. 16XNLQ02. Xiao Qin＇s work is supported by the U.S. National Science Foundation under Grant Nos. IIS-1618669, CCF-0845257 （CAREER）, CNS-0917137, CNS-0757778, CCF-0742187, CNS-0831502, CNS-0855251, and OCI-0753305. Xiao Qin＇s study is also supported by the Programme of Introducing Talents of Discipline to Universities （111 Project） in China under Grant No. B07038.
文摘Deduplication has been commonly used in both enterprise storage systems and cloud storage. To overcome the performance challenge for the selective restore operations of deduplication systems, solid-state-drive-based （i.e., SSD-based） re^d cache cm, be deployed for speeding up by caching popular restore contents dynamically. Unfortunately, frequent data updates induced by classical cache schemes （e.g., LRU and LFU） significantly shorten SSDs＇ lifetime while slowing down I/O processes in SSDs. To address this problem, we propose a new solution -- LOP-Cache to greatly improve tile write durability of SSDs as well as I/O performance by enlarging the proportion of long-term popular （LOP） data among data written into SSD-based cache. LOP-Cache keeps LOP data in the SSD cache for a long time period to decrease the number of cache replacements. Furthermore, it prevents unpopular or unnecessary data in deduplication containers from being written into the SSD cache. We implemented LOP-Cache in a prototype deduplication system to evaluate its pertbrmance. Our experimental results indicate that LOP-Cache shortens the latency of selective restore by an average of 37.3% at the cost of a small SSD-based cache with only 5.56% capacity of the deduplicated data. Importantly, LOP-Cache improves SSDs＇ lifetime by a factor of 9.77. The evidence shows that LOP-Cache offers a cost-efficient SSD-based read cache solution to boost performance of selective restore for deduplication systems.
基金the National High Technology Research and Development Program (863 Program) (2015AA015301),and the National Natural Science Foundation of China (Grant Nos.61472153,61502191).The preliminary conference version appears in the Proceedings of the 45th International Conference on Parallel Processing (ICPP),2016.
文摘Solid-state drives (SSDs)have been widely used as caching tier for disk-based RAID systems to speed up dataintensive applications.However,traditional cache schemes fail to effectively boost the parity-based RAID storage sys- tems (e.g.,RAID-5/6),which have poor random write performance due to the small-write problem.What's worse,intensive cache writes can wear out the SSD quickly,which causes performance degradation and cost increment.In this article,we present the design and implementation of KDD, an efficient SSD-based caching system which Keeps Data and Deltas in SSD.When write requests hit in the cache, KDD dispatches the data to the RAID storage without updating the parity blocks to mitigate the small write penalty, and compactly stores the compressed deltas in SSD to reduce the cache write traffic while guaranteeing reliability in case of disk failures.In addition,KDD organizes the metadata partition on SSD as a circular log to make the cache persistent with low overhead.We evaluate the performance of KDD via both simulations and prototype implementations.Experimental results show that KDD effectively reduces the small write penalty while extending the lifetime of the SSD-based cache by up to 6.85 times.
基金supported by the Yayasan Universiti Teknologi PETRONAS(YUTP)under Cost Center 015LC0-485.
文摘Unmanned aerial vehicles(UAVs)technology is rapidly advancing,offering innovative solutions for various industries,including the critical task of oil and gas pipeline surveillance.However,the limited flight time of conventional UAVs presents a significant challenge to comprehensive and continuous monitoring,which is crucial for maintaining the integrity of pipeline infrastructure.This review paper evaluates methods for extending UAV flight endurance,focusing on their potential application in pipeline inspection.Through an extensive literature review,this study identifies the latest advancements in UAV technology,evaluates their effectiveness,and highlights the existing gaps in achieving prolonged flight operations.Advanced techniques,including artificial intelligence(AI),machine learning(ML),and deep learning(DL),are reviewed for their roles in pipeline monitoring.Notably,DL algorithms like You Only Look Once(YOLO)are explored for autonomous flight in UAV-based inspections,real-time defect detection,such as cracks,corrosion,and leaks,enhancing reliability and accuracy.A vital aspect of this research is the proposed deployment of a hybrid drone design combining lighter-than-air(LTA)and heavier-than-air(HTA)principles,achieving a balance of endurance and maneuverability.LTA vehicles utilize buoyancy to reduce energy consumption,thereby extending flight durations.The paper details the methodology for designing LTA vehicles,presenting an analysis of design parameters that align with the requirements for effective pipeline surveillance.The ongoing work is currently at Technology Readiness Level(TRL)4,where key components have been validated in laboratory conditions,with fabrication and flight testing planned for the next phase.Initial design analysis indicates that LTA configurations could offer significant advantages in flight endurance compared to traditional UAV designs.These findings lay the groundwork for future fabrication and testing phases,which will be critical in validating and assessing the proposed approach’s real-world applicability.By outlining the technical complexities and proposing specialized techniques tailored for pipeline monitoring,this paper provides a foundational framework for advancing UAV capabilities in the oil and gas sector.Researchers and industry practitioners can use this roadmap to further develop UAV-enabled surveillance solutions,aiming to improve the reliability,efficiency,and safety of pipeline monitoring.
基金Supported by the Youth Doctor Support Project of the Education Department of Gansu Province,No.2024QB-100.
文摘BACKGROUND Lung cancer is one of the most common and deadly cancers worldwide.As the disease progresses and due to the side effects of treatment,patients’physical activity significantly decreases.AIM To systematically review and conduct a meta-analysis on the effects of exercise rehabilitation on the physical activity of lung cancer patients and determine the best implementation methods to provide clinical guidance.METHODS Literature was searched through multiple electronic databases.A random effects model was used to combine effect sizes through standardized mean difference(SMD).The Cochrane risk of bias tool was used to assess the quality of the lite-rature,sensitivity analysis was used to ensure the robustness of the results,and Egger’s test was used to detect publication bias and asymmetry.RESULTS A total of 11 studies involving 541 patients were included in this study.The phy-sical endurance,muscle function and cardiopulmonary function of non-small cell lung cancer(NSCLC)patients were evaluated.The overall effect size of the six-minute walk test(6MWT)was not statistically significant.However,subgroup analysis found that endurance significantly improved when exercise duration exceeded 0.5 hours(P≤0.05).In terms of muscle function,the overall effect size was SMD=0.619.Subgroup analysis showed that strength training,respiratory training,and cross-training(XT)significantly improved muscle function.Exercise rehabilitation significantly enhanced cardiopulmonary endurance(SMD=0.856,P=0.002),and the effect was better when the single exercise duration was more than 1 hour,age was over 65 years,and the intervention period was more than 3 months.CONCLUSION Exercise rehabilitation effectively improved muscle function in NSCLC patients,especially strength training,respiratory training,and cross-training.Cardiopulmonary function also showed improvement,particularly when exercise duration exceeded 1 hour,age was≥65 years,and the intervention period was more than 3 months.A single exercise duration of more than 0.5 hours can enhance patients’physical endurance.Appropriately increasing exercise duration and selecting suitable exercise forms can effectively improve the physical activity of NSCLC patients.
文摘Hardship The Double Take column looks at a single topic from an African and Chinese perspective.This month,we explore whether enduring hardship is still a necessary path to growth in a changing world.
文摘1 Originally published in 1993,To Live,a novel by Chinese author Yu Hua has since gained international recognition for its raw emotional depth and exploration of themes like fate,endurance and the essence of humanity.2 The novel follows the life of Xu Fugui,a once⁃wealthy landowner who lost his fortune through gambling(赌博).As his status shifted to that of a peasant,he witnessed the rapid changes of society.Despite enduring relentless hardship,Fugui survived,finding moments of comfort in small and everyday acts of perseverance.
基金supported by the National Natural Science Foundation of China(Grant No.NSFC11932013)National Key Research and Development Program of China(Grant No.2022YFB3805800).
文摘Background:Despite the wide use of compression garments to enhance athletic running performance,evidence supporting improvements has not been conclusive.This updated systematic review and meta-analysis of randomized controlled trials(RCTs)compared the effects of compression garment wearing with those of non-compression garment wearing(controls)during running on improving running performance.Methods:A comprehensive search was conducted in the electronic databases(Web of Science,EBSCOhost,PubMed,Embase,Scopus,and Cochrane)for RCTs comparing running performance between runners wearing compression garments and controls during running,from inception to September 2024.Independent reviewers screened studies,extracted data,appraised risk of bias(RoB 2)and certainty of evidence(Grading of Recommendations Assessments,Development and Evaluation(GRADE)).Primary outcomes were race time and time to exhaustion.Secondary outcomes covered running speed and race pace,submaximal oxygen uptake,tissue oxygenation,and soft tissue vibration.Randomeffects meta-analyses were conducted to generate pooled estimates,expressed in standardized mean difference(SMD).Subgroup differences of garment,race type,and contact surface were tested in moderator analyses.Results:The search yielded 51 eligible studies comprising 899 participants,of which 33 studies were available for meta-analysis of primary outcomes.Runners wearing compression garments during running showed no significant improvement in race time(SMD=-0.07,95%CI:-0.22 to 0.09;p=0.40)or time to exhaustion(SMD=0.04,95%CI:-0.20 to 0.29;p=0.72).Moderator analyses indicated no effects from garment type,race type,or surface.Secondary outcomes also showed no performance benefits,although compression garments significantly reduced soft tissue vibration(SMD=-0.43,95%CI:-0.70 to-0.15;p<0.01).Certainty of evidence was rated low to very low.Conclusion:Data synthesis of current RCTs offers no updated evidence favoring the support of wearing compression garments during running as a viable strategy for improving running and endurance performance among runners of varying performance levels and types of running races.
文摘Background:Sport climbing is becoming incredibly popular both in the general population and among athletes.No consensus exists regarding evidence-based sport-specific performance evaluation;therefore,this systematic review was aimed at analyzing determinants of sport climbing performance and evaluation methods by comparing climbers of different levels.Methods:PubMed,Scopus,and Web of Science were searched up to December 20,2022.Studies providing the self-reported climbing ability associated with different functional outcomes in groups of climbers of contiguous performance levels were eligible.Results:74 studies were finally included.Various methods have been proposed to evaluate determinants of sport climbing performance.Climbing-specific assessments were able to discriminate climbers of different levels when compared to general functional tests.Test validity resulted high for climbing-specific cardiorespiratory endurance as well as muscular-strength,-endurance,and-power;similarly,reliability was good except for cardiorespiratory endurance.Climbing-specific flexibility assessment resulted in high reliability but moderate validity,whereas balance showed low validity.Considerable conflicting evidence was found regarding anthropometric characteristics.Conclusion:The present analysis identified cardiorespiratory endurance as well as muscular-strength,-endurance,and-power as determinants of sport climbing performance.In contrast,balance,flexibility,and anthropometric characteristics seem to count less.This review also proposes an evidence-based Functional Sport Climbing test battery for asses sing performance determinants,which includes tests that have been identified to be valid,reliable,and feasible.While athletes and coaches should rely on evidence-based and standardized evaluation methods,researchers may design specific large-scale trials as a resource for providing additional,homogenous,and comparable data to improve scientific evidence and professionalism in this popular sport discipline.
文摘Rainbows-symbolizing peace,hope,promise and endurance(忍耐力)in hard times-are springing up in neighborhoods throughout Long Island in an effort to color the future road with optimism.The campaign,Rainbows over Nassau and Suffolk Counties and Beyond,started on March 21 and spread through a group.It's a campaign that encourages participants to make rainbows to display outside their homes,anywhere from their front windows and doors to lawns and sidewalks.It follows another similar project,Chalk Your Walk,which promotes writing hopeful messages in chalk on driveways and sidewalks.
基金supported by Exercise Physiologyin Special Population Research Unit,and Faculty of Sports Science Fund,Chulalongkorn University。
文摘Background:Surf skateboards have grown in popularity among young people in recent years.However,no research studies have analyzed the effect of surf skateboarding on physical fitness.Objective:The purpose of this study was to determine the effects of 8-week surf skateboard training on physical fitness in young adults.Methods:Twenty-two young people,ages 18–24 years were randomly assigned into two groups:a control(CON;n=11)and surf skateboarding(SSK;n=11)group.The surf skateboard training group received an eight-week intervention consisting of three 60-minute(min)sessions per week,while the control group continued with their normal daily lives.Physical fitness was assessed before and after the intervention through a battery of tests that included body composition,cardiorespiratory fitness,muscular strength and endurance,flexibility,and balance.Results:The results showed that the SSK group demonstrated significant(p<0.05)improvements in maximum voluntary ventilation,back and leg strength,lower body muscular endurance by the sit-to-stand tests,and balance in all direction compared with the pre-test and the CON group.In addition,the SSK group showed significantly(p<0.05)decreased body weight,body mass index,percent body fat,and resting heart rate,while increased maximum oxygen consumption,pulmonary function,respiratory muscle strength,upper body muscular endurance by the sit-up test and flexibility compared with the pre-test.Conclusion:The findings suggest that surf skateboard training have an effective physical activity intervention to improve body composition,cardiorespiratory fitness,muscular strength and endurance,flexibility,and balance in young people.
文摘BACKGROUND In pediatric and adolescent athletes,there is a lack of understanding about the impact of factors such as race on the structural or cardiovascular adaptations in response to exercise which may unnecessarily disqualify athletes from the competitive sport.We hypothesized that race has an impact on cardiac adaptions in non-adult athletes.AIM To explore the racial disparity in electrocardiographic(ECG)and echocardiographic(ECHO)parameters in healthy adolescent athletes.METHODS A comprehensive electronic systematic literature search using MEDLINE database was performed from inception to September 20,2024.Inclusion criteria included randomized or observational cohort studies that recruited adolescent competitive athletes in any sport discipline and compared between the Black and White races with an age range of 12-18 years.RESULTS Of 723 records that were identified by the literature search,seven studies(n=5036)were included.The mean age was 13.0-18.0 years old with male predominance.Black athletes had significantly longer PR interval[mean difference(MD)=17.49 millisecond,95% CI:11.70-23.29]and shorter QRS complex duration(MD=-7.35 millisecond,95% CI:-9.17 to-5.53)and corrected QT interval(MD=-4.95 millisecond,95% CI:-7.69 to-2.22)than the White athletes.Black athletes were approximately four times more likely to have first-degree atrioventricular(AV)block,inverted T wave,ST-segment elevation,and left atrium(LA)enlargement than their White counterparts.In terms of ECHO parameters,Black athletes had significantly greater septal wall thickness(MD=0.85 mm,95% CI:0.62-1.07),posterior wall thickness(MD=1.07 mm,95% CI:0.36-1.78),relative wall thickness(MD=0.03,95%CI:0.001-0.06),maximal wall thickness(MD=1.05 mm,95%CI:0.28-1.83),and LA diameter(MD=1.64 mm,95%CI:0.16-3.12).CONCLUSION Race has an impact on the ECG and ECHO parameters that reflect cardiac adaptations in adolescent athletes.Black athletes tend to have an increased prevalence of distinct ECG changes such as first-degree AV block and T-wave inversions compared with their White counterparts.Despite having thicker septal and posterior walls,the overall prevalence of left ventricular hypertrophy did not differ between the races.
基金supported by the Polish Ministry of Science and Higher Education,grant no.2/566516/SPUB/SP/2023。
文摘Background:Habitual physical activity is known to support cardiovascular health.However,when intensive exercise is performed for long durations,it can negatively affect the cardiovascular system.We evaluated the exercise-induced physiological responses of cardiac markers in male marathon runners based on basal plasma trimethylamine-N-oxide(TMAO)levels,a metabolite related to major adverse cardiovascular events.Methods:Blood samples from 28 marathon runners were collected two weeks before the marathon run(baseline),after finishing the race(post-marathon),and two weeks after the race(2 weeks post-marathon).Serum cardiac troponin I(c Tn I),endothelin-1(ET-1),galectin-3,pentraxin-3,human growth differentiation factor 15,and neopterin were determined by the enzyme immunoassay method.Plasma trimethylamine(TMA)and TMAO were measured by the ultra-high-performance liquid chromatography-mass spectrometry method.Results:Running a marathon increased levels of circulating biomarkers.A greater post-marathon elevation of cTn I and ET-1 was associated with baseline plasma TMAO levels(R=0.400,p=0.035 and R=0.476,p=0.012,respectively).Moreover,we observed an increase in post-marathon TMA levels.Conclusion:Greater post-marathon elevation of cTn I and ET-1 was associated with higher baseline plasma TMAO levels.Therefore,TMAO could potentially serve as a new marker in assessing the response of cardiovascular stress biomarkers to marathon running.
文摘Tennis,a popular sport in colleges and universities,is deeply loved by teachers and students.However,due to its high physical demands,technical difficulty,and other characteristics,it requires a high level of physical fitness.Compared to competitive tennis,although college tennis instruction may lack competitiveness and involve lower exercise intensity,it still necessitates regular physical training to enhance body coordination,balance,and agility.This can help students stay physically fit while avoiding injuries.This article explores the content of physical training in college tennis instruction,clarifies the important role of physical training,and summarizes a series of physical training pathways to provide reference support for physical training in college tennis instruction.
基金supported by the Fundamental Research Funds for the Central Universities(Grant No.HUST:5003190012)the Natural Science Foundation of Hubei Province(Grant No.2024AFA043).
文摘Along with NOR flash cell scaling down,dielectric burnout has gradually become one of the most important factors which affects product reliability,especially for high dropout voltage films.In this study,we demonstrate a reliability-enhanced NOR flash cell in 50 nm node technology through structural optimization of floating gate(FG)dimensions and active area profile.By synergistically increasing FG thickness,reducing FG width,and tuning cell-open depth,the control gate-to-active area corner distance expands by 22%,suppressing peak electric fields by 29%vertically and 18%horizontally.This structural innovation achieves:(1)100×reduction in early-cycle burnout failures,(2)7.38×time dependent dielectric breakdown lifetime improve-ment,while maintaining data retention and accelerating programming/erasing speeds by 15.4%/7.3%.The enhanced reliability enables 97.5%reduction in Fowler−Nordheim stress time during characterization program testing,providing a cost-effective solution for automotive-grade flash memories.
文摘Before you can tie your shoelaces for one of the worlds most remote races,you must first navigate through wild seas,endure(忍受)freezing temperatures and go on a journey that tests more than just your physical endurance.This is no ordinary race;it requires thorough preparation and a strong will.
