Mitochondrial encephalopathy,lactic acidosis,and stroke-like episodes(MELAS)syndrome is a complex mitochondrial disorder.[1]It exhibits a diverse range of clinical symptoms affecting multiple organ systems.[1]We are e...Mitochondrial encephalopathy,lactic acidosis,and stroke-like episodes(MELAS)syndrome is a complex mitochondrial disorder.[1]It exhibits a diverse range of clinical symptoms affecting multiple organ systems.[1]We are exploring the intriguing link between MELAS and an elevated risk of infections.The systemic consequences of mitochondrial dysfunction,disrupting vital energy production processes,extend beyond neurological representation.[1]We emphasize 2 key elements that lead to a higher risk of infection:overall immune system dysfunction and reduced antibody production.Mitochondrial dysfunction compromises immune cell function,making it difficult to build a strong defense against pathogens.展开更多
文摘Mitochondrial encephalopathy,lactic acidosis,and stroke-like episodes(MELAS)syndrome is a complex mitochondrial disorder.[1]It exhibits a diverse range of clinical symptoms affecting multiple organ systems.[1]We are exploring the intriguing link between MELAS and an elevated risk of infections.The systemic consequences of mitochondrial dysfunction,disrupting vital energy production processes,extend beyond neurological representation.[1]We emphasize 2 key elements that lead to a higher risk of infection:overall immune system dysfunction and reduced antibody production.Mitochondrial dysfunction compromises immune cell function,making it difficult to build a strong defense against pathogens.
