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Systemic immune indicators: Early predictors of renal damage in children with newly diagnosed type 1 diabetes mellitus
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作者 Basavraj S Nagoba Ajay M Gavkare +2 位作者 Neeta Nanaware Sachin S Mumbre Sachin Bhavthankar 《World Journal of Diabetes》 2025年第7期8-15,共8页
This editorial delves into the potential of systemic immune indicators(SIIs)as early predictors of renal damage in children with newly diagnosed type 1 diabetes mellitus.By exploring the recent study published by Cao ... This editorial delves into the potential of systemic immune indicators(SIIs)as early predictors of renal damage in children with newly diagnosed type 1 diabetes mellitus.By exploring the recent study published by Cao et al,this article aims to highlight the importance of early detection and intervention.This study compre-hensively analyzes various SIIs,examining their correlation with renal compli-cations in newly diagnosed type 1 diabetic children.The findings reveal a sig-nificant association between immune system dysregulation and the onset of renal damage,suggesting that certain immune indicators can be early markers for predicting renal complications.This editorial emphasizes the clinical implications and applications of utilizing SIIs for early detection in pediatric diabetes care.It underscores the importance of innovative diagnostic approaches and illustrates real-world applications and outcomes.Additionally,it addresses the challenges and considerations in adopting these indicators and outlines future research directions to enhance diabetes management in children. 展开更多
关键词 Systemic immune indicators Type 1 diabetes Renal damage Pediatric care Early predictors
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Damage indices for RC columns under three-dimensional excitation
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作者 Zhang Haoyu Mao Chenxi Zhou Wei 《Earthquake Engineering and Engineering Vibration》 2025年第2期357-380,共24页
Damage indices are effective in quantifying structural seismic damage.Numerous response-based damage indices have been developed and validated through the hysteretic response of various experimental specimens.However,... Damage indices are effective in quantifying structural seismic damage.Numerous response-based damage indices have been developed and validated through the hysteretic response of various experimental specimens.However,the accuracy of these indices for evaluating damage of RC columns is challenged by fluctuating axial load and irregular horizontal loading paths from 3-D earthquake excitations.This study introduces D_(iem),a material-based damage model for RC columns under random bidirectional loads and variable axial forces.Section damage indices of the plastic hinge are calculated by integrating the damage indices of concrete and steel fiber elements,considering their distance to the centroid axis.The P-Δeffect index is defined,and the component failure index is calculated using a combination of these indices.A hysteretic simulation and D_(iem)damage analysis program for cantilever RC columns is developed using Fortran.Three RC columns tested under bidirectional hysteretic loading are simulated to calibrate the program.Parameter analysis of 1,638 RC columns is conducted to verify D_(iem)’s applicability.The results demonstrated that D_(iem)’s failure assessment aligns with the 80%residual criterion.D_(iem)analysis of a real seismic damaged RC column shows satisfactory agreement with post-earthquake damage assessment and illustrates significant damage differences between columns with and without axial load fluctuation. 展开更多
关键词 damage indices three-dimensional seismic loading material damage indices integration of element materials
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Development of fragility curves by incorporating new spectral shape indicators and a weighted damage index:case study of steel braced frames in the city of Mashhad,Iran 被引量:5
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作者 Hamid Kazemi Mohsen Ghafory-Ashtiany Alireza Azarbakht 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2017年第2期383-395,共13页
In this study, strong ground motion record (SGMR) selection based on Eta (~/) as a spectral shape indicator has been investigated as applied to steel braced flame structures. A probabilistic seismic hazard disaggr... In this study, strong ground motion record (SGMR) selection based on Eta (~/) as a spectral shape indicator has been investigated as applied to steel braced flame structures. A probabilistic seismic hazard disaggregation analysis for the definition of the target Epsilon (ε) and the target Eta (η) values at different hazard levels is presented, taking into account appropriately selected SGMR's. Fragility curves are developed for different limit states corresponding to three representative models of typical steel braced frames having significant irregularities in plan, by means of a weighted damage index. The results show that spectral shape indicators have an important effect on the predicted median structural capacities, and also that the parameter r/is a more robust predictor of damage than searching for records with appropriate c values. 展开更多
关键词 VULNERABILITY spectral shape indicator incremental dynamic analysis damage index hazard disaggregation record selection
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Damage Assessment of Reinforced Concrete Structures through Damage Indices:A State-of-the-Art Review 被引量:3
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作者 D.A.Makhloof A.R.Ibrahim Xiaodan Ren 《Computer Modeling in Engineering & Sciences》 SCIE EI 2021年第9期849-874,共26页
Due to the developments of computer science and technology in recent years,computer models and numerical simulations for large and complicated structures can be done.Among the vast information and results obtained fro... Due to the developments of computer science and technology in recent years,computer models and numerical simulations for large and complicated structures can be done.Among the vast information and results obtained from the analysis and simulations,the damage performance is of great importance since this damage might cause enormous losses for society and humanity,notably in cases of severe damage occurring.One of the most effective tools to handle the results about the damage performance of the structure is the damage index(DI)together with the damage states,which are used to correlate the damage indices with the damage that occurred in the actual structures.Numbers of damage indices proposed and developed rely on the fact that the damage causes noticeable changes in the structural and dynamic properties of the structural components or the whole structure.Therefore,this study presents a comprehensive review of the damage assessment of Reinforced Concrete(RC)structures.It presents step by step the development of the damage indices that are most widely used to estimate the performance of structural components in the structure and subsequently assess the damage degree of such these structures either based on the structural properties or dynamic properties of the structure.Also,several damage states have been introduced to estimate the performance level of the structure.Finally,case studies,methodologies,and applications on the damage assessment of RC structures are reviewed and presented. 展开更多
关键词 Structure properties-based damage indices dynamic properties-based damage indices damage states
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Quantitative analysis of seismic damage information of masonry buildings based on terrestrial LiDAR data
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作者 Yang Fan Wang Xiaoshan +4 位作者 Liu Xiaodan Fan Zhiwei Wen Chao Li Xiaoli Li Zhiqiang 《Earthquake Engineering and Engineering Vibration》 2025年第3期743-761,共19页
In this study,terrestrial laser scanning(TLS)is used to collect building data after the M_(s) 7.0 magnitude earthquake in Lushan,Sichuan,China in 2013 for analysis and research.The analysis focuses on extracting the t... In this study,terrestrial laser scanning(TLS)is used to collect building data after the M_(s) 7.0 magnitude earthquake in Lushan,Sichuan,China in 2013 for analysis and research.The analysis focuses on extracting the tilt and deformation of masonry buildings that are difficult to identify through visual inspection in basically intact,slightly damaged and moderately damaged masonry buildings,to solve the problem of ambiguous identification of damage.A quantitative analysis of the determination indexes of the degree of earthquake damage was carried out,and the numerical characteristics parameters such as the curvature of the wall point cloud proximity,angle,contour of the fitted plane of the point cloud,verticality(flatness)of the wall,standard deviation of the profile and angle of the profile were established to determine the degree of earthquake damage to buildings based on LiDAR data.The development of quantitative determination indexes for the degree of earthquake damage of buildings in this study has important application value for LiDAR data in the identification and extraction of earthquake damage information and damage level determination. 展开更多
关键词 terrestrial laser scanning LIDAR BUILDINGS degree of earthquake damage judgment indicators
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Damage detection in steel plates using feed-forward neural network coupled with hybrid particle swarm optimization and gravitational search algorithm 被引量:2
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作者 Long Viet HO Duong Huong NGUYEN +2 位作者 Guido de ROECK Thanh BU-TIEN Magd Abdel WAHAB 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2021年第6期467-480,共14页
Over recent decades,the artificial neural networks(ANNs)have been applied as an effective approach for detecting damage in construction materials.However,to achieve a superior result of defect identification,they have... Over recent decades,the artificial neural networks(ANNs)have been applied as an effective approach for detecting damage in construction materials.However,to achieve a superior result of defect identification,they have to overcome some shortcomings,for instance slow convergence or stagnancy in local minima.Therefore,optimization algorithms with a global search ability are used to enhance ANNs,i.e.to increase the rate of convergence and to reach a global minimum.This paper introduces a two-stage approach for failure identification in a steel beam.In the first step,the presence of defects and their positions are identified by modal indices.In the second step,a feedforward neural network,improved by a hybrid particle swarm optimization and gravitational search algorithm,namely FNN-PSOGSA,is used to quantify the severity of damage.Finite element(FE)models of the beam for two damage scenarios are used to certify the accuracy and reliability of the proposed method.For comparison,a traditional ANN is also used to estimate the severity of the damage.The obtained results prove that the proposed approach can be used effectively for damage detection and quantification. 展开更多
关键词 Feedforward neural network-particle swarm optimization and gravitational search algorithm(FNN-PSOGSA) Modal damage indices damage detection Hybrid algorithm PSOGSA
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Damage Identification of Wind Turbine Blades–A Brief Review 被引量:1
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作者 Amna Algolfat Weizhuo Wang Alhussein Albarbar 《Journal of Dynamics, Monitoring and Diagnostics》 2023年第3期198-206,共9页
The increasing size of these blades of wind turbines emphasizes the need for reliable monitoring and maintenance.This brief review explores the detection and analysis of damage in wind turbine blades.The study highlig... The increasing size of these blades of wind turbines emphasizes the need for reliable monitoring and maintenance.This brief review explores the detection and analysis of damage in wind turbine blades.The study highlights various techniques,including acoustic emission analysis,strain signal monitoring,and vibration analysis,as effective approaches for damage detection.Vibration analysis,in particular,shows promise for fault identification by analyzing changes in dynamic characteristics.Damage indices based on modal properties,such as natural frequencies,mode shapes,and curvature,are discussed. 展开更多
关键词 damage modeling digital twin vibration-based indices wind turbine blade
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Damage Detection Method Using Support Vector Machine and First Three Natural Frequencies for Shear Structures
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作者 Hien HoThu Akira Mita 《Open Journal of Civil Engineering》 2013年第2期104-112,共9页
A method is proposed for detecting damage to shear structures by using Support Vector Machine (SVM) and only the first three natural frequencies of the translational modes. This method is able to determine the damage ... A method is proposed for detecting damage to shear structures by using Support Vector Machine (SVM) and only the first three natural frequencies of the translational modes. This method is able to determine the damage location in any story of a shear building with only two vibration sensors;to obtain modal frequencies, one sensor on the ground detects an input and the other on the roof detects the output. Based on the shifts in the first three natural frequencies, damage location indicators are proposed, and used as new feature vectors for SVM. Simulations of five-story, nine-story and twenty-one-story shear structures and experiments on a five-story steel model were used to test the performance of the proposed method. 展开更多
关键词 Support VECTOR Machine damage Detection Natural Frequency System Identification damage LOCATION indicator
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高烈度区悬索桥钢管混凝土索塔地震损伤分析
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作者 刘政超 张谢东 +2 位作者 于建华 陈甫君 吴斌 《武汉理工大学学报(交通科学与工程版)》 2026年第1期212-216,222,共6页
采用增量动力分析的方法,以地面峰值加速度为增量,对悬索桥新型索塔结构进行地震损伤分析.建立结构有限元动力模型,着重描述钢管混凝土索塔,基于PEER强震数据库选取了10条地震记录,在17个地震强度加载下对索塔横桥向与顺桥向两个方向进... 采用增量动力分析的方法,以地面峰值加速度为增量,对悬索桥新型索塔结构进行地震损伤分析.建立结构有限元动力模型,着重描述钢管混凝土索塔,基于PEER强震数据库选取了10条地震记录,在17个地震强度加载下对索塔横桥向与顺桥向两个方向进行动力响应分析;以索塔塔底截面为主要研究对象,选取适当的损伤指标建立截面在不同损伤状态下的限值,通过统计学方法绘制截面的易损性曲线.得出在不同地震输入方向、不同地面峰值加速度下,悬索桥塔底损伤状态和概率. 展开更多
关键词 桥梁工程 地震易损性 增量动力分析法 损伤指标 钢管混凝土结构
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复合材料层合板结构的自适应正则化损伤识别(ARDI)方法研究
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作者 杨颖 石庆贺 +3 位作者 胡可军 朱福先 段刘阳 赵凤玲 《复合材料科学与工程》 北大核心 2026年第2期1-9,19,共10页
复合材料层合板结构应用广泛,损伤识别对于保障结构的安全性和延长其使用寿命具有重要意义。本文引入了单元级损伤指标来描述层合板在面内与面外方向上的刚度变化。针对该损伤指标,建立了两步损伤识别方法,即先通过损伤定位指标筛选损... 复合材料层合板结构应用广泛,损伤识别对于保障结构的安全性和延长其使用寿命具有重要意义。本文引入了单元级损伤指标来描述层合板在面内与面外方向上的刚度变化。针对该损伤指标,建立了两步损伤识别方法,即先通过损伤定位指标筛选损伤单元,再通过优化方法对损伤程度进行辨识,其中,损伤定量识别采用正则化方法。鉴于传统的正则化方法对各个损伤参数采用均一化的正则化参数,不利于识别结果的收敛和稳定,本文提出了基于加权系数的自适应正则化损伤识别(Adaptive Regularization Damage Identification,ARDI)方法,能够在兼顾识别结果稳定性的同时提高识别效率。通过数值算例对所提方法的有效性进行了验证,分析了测点数量和噪声水平对识别结果的影响,将所提方法与直接法和传统正则化方法的识别结果进行比较,发现所提方法的计算结果分散性和计算效率具有明显的优势。最后,通过试验验证了所提方法的有效性。 展开更多
关键词 复合材料 单元级损伤指标 损伤定位 自适应正则化 损伤定量
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经典名方茯苓桂枝甘草大枣汤古今文献考证
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作者 张傲 陈心语 +2 位作者 王兴杰 颜秉硕 殷寻嫣 《河南中医》 2026年第1期67-76,共10页
目的:考证茯苓桂枝甘草大枣汤源流演变,确证其方源、组成、剂量、炮制、煎服法及主治等关键信息,为其传承与标准化应用奠定基础。方法:古代文献分析:采用文献计量学方法,系统检索古籍,运用历史比较、版本校勘、训诂考据等方法,结合多重... 目的:考证茯苓桂枝甘草大枣汤源流演变,确证其方源、组成、剂量、炮制、煎服法及主治等关键信息,为其传承与标准化应用奠定基础。方法:古代文献分析:采用文献计量学方法,系统检索古籍,运用历史比较、版本校勘、训诂考据等方法,结合多重质控与证据分级,对方剂源流、异名演变、医家注解、药物组成、剂量折算、炮制规范、煎服细节及主治病症进行系统考证与量化分析。现代文献分析:依托中国知网与万方数据平台,以“茯苓桂枝甘草大枣汤”“临床”“医案”“疗效”为主题词进行检索,时间跨度为1983年1月至2025年7月。结果:本方源流清晰,出自东汉张仲景所著《伤寒论》,药物组成茯苓、桂枝、甘草、大枣在全部考证医籍中完全一致。以宋本《伤寒论》为基准,明确原方剂量为茯苓半斤折125 g,桂枝四两折62.5 g,甘草二两折31.25 g,大枣十五枚折45 g;规范炮制要求为桂枝去粗皮、甘草蜜炙、茯苓净制去筋、大枣擘破;煎服法为甘澜水2000 mL,先煮茯苓至1600 mL,后纳余药煮取600 mL,温服200 mL,每日3次。核心主治界定为发汗后脐下悸动、气欲上冲,此记载占考证文献主流,历代医家对相关症状延伸或兼症补充均未脱离此核心病症范畴。现代文献分析:共纳入有效文献20篇,大多聚焦于所治“奔豚病”,近年来应用本方治疗他病有所增多,如治疗脾胃系疾病之呃逆等。结论:茯苓桂枝甘草大枣汤各项关键信息明确,为该经典名方准确传承、标准化应用及现代研究与拓展提供了文献学依据。 展开更多
关键词 茯苓桂枝甘草大枣汤 文献考证 文献计量学 方剂源流 剂量 炮制 煎服法 主治病症 经典名方 《伤寒论》 张仲景
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Clinical implication of hematological indices in the essential hypertension 被引量:2
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作者 Ahmet Karabulut Aytac Karadag 《World Journal of Hypertension》 2015年第2期93-97,共5页
Prognostic value of haematological indices,especially red cell distribution width,neutrophil lymphocyte ratio and mean platelet volume,was reported with numerous investigations in miscellaneous cardiovascular settings... Prognostic value of haematological indices,especially red cell distribution width,neutrophil lymphocyte ratio and mean platelet volume,was reported with numerous investigations in miscellaneous cardiovascular settings.Their major prognostic value was linked to oxidative stress and inflammation since their level was correlated with major inflammatory markers such as high sensitive C-reactive protein and interleukins.Oxidative stress and chronic inflammation are also postulated as the main pathophysiologic mechanism of essential hypertension(HT) and its vascular complication.Recently,correlation between HT and haematological parameters was searched in numerous studies,which has made the topic more popular.Herein,we reveal the correlation between haematological indices and HT and we also demonstrate the clinical implication of this correlation.Impaired haematological parameters may strongly indicate hypertensive end-organ damage. 展开更多
关键词 HYPERTENSION INFLAMMATION End-organ damage Haematological indice PLATELET activation
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基于强度和能量理论的应变型岩爆机理研究 被引量:3
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作者 薛亚东 田恒蛟 何本国 《工程地质学报》 北大核心 2025年第2期471-481,共11页
岩爆是深埋隧道建设过程中弹性应变能突然释放的一种脆性动力失稳,岩块弹射具有突发性和破坏性,带来严重的经济损失、人员伤亡、工期延误等,深入地理解岩爆的形成机理对隧道工程建设具有重要意义。在考虑岩体完整性系数K_(v)和岩石风化... 岩爆是深埋隧道建设过程中弹性应变能突然释放的一种脆性动力失稳,岩块弹射具有突发性和破坏性,带来严重的经济损失、人员伤亡、工期延误等,深入地理解岩爆的形成机理对隧道工程建设具有重要意义。在考虑岩体完整性系数K_(v)和岩石风化系数K_(f)的基础上,提出了改进Mohr-Coulomb强度准则(GM-C)的判别指数Q_(gMC)和Drucker-Prager强度准则(GD-P)的判别指数Q_(gDP)的计算方法。利用Griffith准则,从微观到宏观的角度对微裂纹的形成、扩展、合并与集聚进行分析,建立了考虑损伤因子D的岩石黏聚力c和内摩擦角φ的计算公式。通过引入岩爆倾向性指标P,考虑围岩等级对岩爆倾向性的影响,提出了综合考虑强度准则和能量理论的应变型岩爆等级的判断方法。选取了国内多个工程12个不同点位处的岩爆状态数据对所提出的岩爆等级判断方法进行工程验证。结果表明,通过先计算岩石强度准则的判别指数Q的值来判断岩石是否发生屈服破坏,然后再计算岩爆倾向性指标P的值来判断岩爆发生的等级是可行的。这种综合考虑强度准则和能量理论的应变型岩爆等级的判断方法对隧道施工现场的工作人员能准确及时地判断岩爆等级提供了一种新方法和新思路。 展开更多
关键词 岩爆 强度准则 损伤因子 能量理论 岩爆倾向性指标
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血必净联合乌司他丁及奥曲肽治疗重症急性胰腺炎的有效性及对炎症指标的影响 被引量:4
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作者 陈涛 张昕 李兆芳 《天津药学》 2025年第1期78-81,共4页
目的探究重症急性胰腺炎(SAP)予以血必净、乌司他丁及奥曲肽联合治疗的有效性及对炎症指标影响。方法选择2021年10月至2024年8月,选择中国人民解放军联勤保障部队第九〇人医院收治的60例SAP患者,按随机数字表法分2组,各30例。对照组予... 目的探究重症急性胰腺炎(SAP)予以血必净、乌司他丁及奥曲肽联合治疗的有效性及对炎症指标影响。方法选择2021年10月至2024年8月,选择中国人民解放军联勤保障部队第九〇人医院收治的60例SAP患者,按随机数字表法分2组,各30例。对照组予以乌司他丁及奥曲肽治疗,观察组联合血必净治疗,均持续治疗10 d。比较两组临床疗效、炎症指标、肠黏膜损伤程度、免疫功能、不良反应。结果观察组治疗总有效率(93.33%)较对照组(73.33%)高,治疗后肿瘤坏死因子-α(TNF-α)(20.53±1.55)pg/mL、降钙素原(PCT)(3.42±0.53)mg/L、C反应蛋白(CRP)(43.55±2.76)mg/L、白细胞介素-6(IL-6)(35.75±2.46)pg/mL均较对照组低,D-乳酸、血清内毒素均较对照组低,CD3^(+)、CD4^(+)均较对照组高,CD8^(+)较对照组低,有统计学差异(P<0.05);对比两组不良反应,无统计学差异(P>0.05)。结论血必净联合乌司他丁及奥曲肽治疗SAP患者可有效减轻炎症反应及肠黏膜损伤,改善免疫功能,且安全可靠。 展开更多
关键词 重症急性胰腺炎 血必净 乌司他丁 奥曲肽 炎症指标 肠黏膜损伤程度 免疫功能
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重载撞击和火灾耦合作用下盾构隧道损伤与韧性分析
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作者 张治国 韩哲 +4 位作者 薛光桥 苟开兵 朱正国 罗驰恒 吴鑫林 《铁道科学与工程学报》 北大核心 2025年第11期5078-5092,共15页
随着地下空间的发展,盾构隧道被广泛应用于地铁、公路等基础设施建设中,在运营过程中可能会发生车辆失控撞击隧道壁,引发火灾这种耦合灾害。目前研究主要基于单性能指标,分析单一灾害下隧道损伤或韧性,对重载撞击和火灾耦合的影响考虑... 随着地下空间的发展,盾构隧道被广泛应用于地铁、公路等基础设施建设中,在运营过程中可能会发生车辆失控撞击隧道壁,引发火灾这种耦合灾害。目前研究主要基于单性能指标,分析单一灾害下隧道损伤或韧性,对重载撞击和火灾耦合的影响考虑较少。以马鞍山湖北路过江通道工程为背景,对耦合灾害下盾构隧道多性能指标进行损伤和韧性分析。首先,确定盾构隧道结构韧性性能的评价指标和计算方法,采用主客观赋权法和DEMATEL法对隧道多性能指标进行综合权重计算;然后,利用有限元软件建立车辆撞击盾构隧道和隧道火灾的三维数值模型,将隧道分为有防撞结构和无防撞结构,根据撞击速度和火灾温度的不同,设置后车撞击前车等多种工况,并从多指标角度对盾构隧道性能进行损伤分析;最后,基于多阶段隧道结构韧性分析模型对盾构隧道进行韧性分析,划分韧性等级。研究结果表明:在重载撞击和火灾耦合作用下,横向收敛变形在该耦合灾害下盾构隧道多性能指标中所占比重较大;盾构隧道6个指标性能随着撞击速度和火灾温度的提高,其性能不断下降;无防撞结构隧道综合性能指数位于0.25~0.60,有防撞结构隧道综合性能指数位于0.72~0.87;无防撞结构韧性指数位于0.35~0.63,有防撞结构隧道韧性指数位于0.77~0.89,防撞结构可使隧道性能和韧性得到较大提升。研究重载撞击和火灾耦合作用下的衬砌损伤和韧性,可以为盾构隧道的安全设计与灾后修复提供理论指导和技术支持。 展开更多
关键词 盾构隧道 韧性 损伤 车撞 火灾 性能指标 防撞结构
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方钢管型钢再生混凝土组合柱地震损伤性能及计算模型研究
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作者 章晴雯 马辉 张国恒 《实验力学》 北大核心 2025年第5期666-680,共15页
为探究地震作用下方钢管型钢混凝土组合柱的破坏形态和损伤性能,本文设计制作了9根组合柱试件,通过低周反复荷载试验研究了组合柱的地震损伤特征及滞回性能指标,并研究了方钢管宽厚比、配钢率、轴压比及再生骨料取代率等参数对组合柱滞... 为探究地震作用下方钢管型钢混凝土组合柱的破坏形态和损伤性能,本文设计制作了9根组合柱试件,通过低周反复荷载试验研究了组合柱的地震损伤特征及滞回性能指标,并研究了方钢管宽厚比、配钢率、轴压比及再生骨料取代率等参数对组合柱滞回性能的影响规律。在此基础上,考虑到最大位移变形和滞回累积耗能对组合柱地震损伤性能的影响程度,通过反演法对Park-Ang地震损伤模型进行系数修正,提出了符合组合柱地震损伤特征及规律的计算模型,进而深入分析了不同设计参数下组合柱地震损伤指数的发展规律。基于上述研究结果,将组合柱的性态水平分为正常使用、暂时使用、修复后使用、生命安全和防止倒塌5个等级;结合组合柱的性态水平和地震损伤指标,确立了组合柱的地震损伤破坏状态、性能水平、可修复程度、界限位移角和界限损伤指标之间的关系,得到了组合柱在各性能水准下对应的位移角限值分别为1/170、1/106、1/50、1/35、1/30。本文研究结论可为评估该类型组合柱在地震作用下的损伤性能提供参考。 展开更多
关键词 组合柱 型钢再生混凝土 方钢管混凝土 地震损伤性能 损伤量化指标
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多指标联合检测对多发性骨髓瘤早期肾损伤患者的诊断及预后评估价值
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作者 杜彦艳 李洁 +4 位作者 周文烨 马鸣 崔雯瑄 王振达 姚影珍 《癌变·畸变·突变》 2025年第5期389-392,399,共5页
目的:探讨实验室多指标联合检测在多发性骨髓瘤(MM)患者早期肾损伤诊断及预后评估中的应用价值。方法:选取2018年11月—2023年5月河北医科大学第四医院血液内科收治的95例初诊MM患者作为研究对象,根据血肌酐(SCr)水平将患者分为非肾损伤... 目的:探讨实验室多指标联合检测在多发性骨髓瘤(MM)患者早期肾损伤诊断及预后评估中的应用价值。方法:选取2018年11月—2023年5月河北医科大学第四医院血液内科收治的95例初诊MM患者作为研究对象,根据血肌酐(SCr)水平将患者分为非肾损伤组(71例)与肾损伤组(24例),并收集其临床病理资料及血常规、凝血功能、生化等相关实验室检测指标。另选取30例无良恶性肿瘤、心血管等疾病的健康志愿者作为对照组。比较各组患者各指标的差异,绘制ROC曲线评价中性粒细胞/淋巴细胞比值(NLR)、单核细胞/淋巴细胞比值(MLR)、全身性炎症反应指数(SIRI)和血浆纤维蛋白原/血清白蛋白比值(FAR)对MM患者发生肾损伤的预测价值,并分析其与MM患者分期及瘤负荷的相关性。结果:MM患者合并肾损伤组NLR、MLR、SIRI和FAR等指标的水平明显高于对照组和MM患者非肾损伤组(P<0.05);ROC曲线显示其对MM患者发生肾损伤具有预测价值(P<0.05),4个指标联合检测对MM患者合并肾损伤辅助诊断应用价值更高;通过logistic回归分析发现NLR、MLR、SIRI和FAR均与MM患者是否发生肾损伤密切相关。其中,NLR升高是MM患者发生肾损伤的独立危险因素。卡方检验结果显示,MLR与MM患者ISS分期密切相关(P<0.05)。结论:NLR、MLR、SIRI、FAR与MM患者肾损伤的临床进展密切相关,四者联合检测可预测MM患者发生肾损伤的临床进展,将炎症指标作为辅助指标应用于MM合并肾损伤的临床诊疗具有重要价值。 展开更多
关键词 多发性骨髓瘤肾损伤 肿瘤标志物 中性粒细胞/淋巴细胞比值 单核细胞/淋巴细胞比值 炎症指标
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损伤控制技术与常规外科急救治疗对急诊严重腹部创伤患者疗效的比较研究
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作者 林虔 曾明亮 +1 位作者 张周斌 黄希宏 《中国医药指南》 2025年第33期124-126,共3页
目的对比损伤控制(DCS)技术与常规外科急救治疗急诊严重腹部创伤患者的效果。方法回顾本院66例急诊严重腹部创伤患者(2022年1月至2025年1月)资料,按急救治疗方案不同分为两组。接受DCS技术治疗的33例患者为研究组,接受常规外科急救治疗... 目的对比损伤控制(DCS)技术与常规外科急救治疗急诊严重腹部创伤患者的效果。方法回顾本院66例急诊严重腹部创伤患者(2022年1月至2025年1月)资料,按急救治疗方案不同分为两组。接受DCS技术治疗的33例患者为研究组,接受常规外科急救治疗的33例患者为对照组。对比两组围手术期相关指标、治疗前、治疗后1 d体征指标、急性生理和慢性健康评估Ⅱ(APACHEⅡ)评分、并发症发生率。结果研究组首次进食时间、留置引流管时间、住院时间、体温恢复时间较对照组短(P<0.05);治疗后1 d研究组体温、血氧饱和度较对照组高(P<0.05);治疗后1 d研究组急性生理学评分及总分较对照组低(P<0.05);研究组并发症发生率较对照组低(P<0.05)。结论相较于常规外科急救治疗急诊严重腹部创伤患者,经DCS技术治疗更有助于优化围手术期相关指标、改善体征,降低并发症风险,促进患者恢复。 展开更多
关键词 腹部创伤 并发症发生率 住院时间 损伤控制技术 体征指标 应激反应
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生态环境损害鉴定中的生态效应评价问题探讨 被引量:2
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作者 冷雨凝 孙婷 +4 位作者 王丽莎 赵苗苗 屈政君 黄理辉 高振会 《山东科学》 2025年第2期117-125,共9页
生态效应评价是生态环境损害鉴定评估中的关键问题,也是生态损害赔偿和修复的重要依据。通过文献调研,系统分析了生态环境损害鉴定中的生态效应评价指标与方法、损害鉴定路径。通过案例探讨,证实了所构建模型在科学评估污染物对生态系... 生态效应评价是生态环境损害鉴定评估中的关键问题,也是生态损害赔偿和修复的重要依据。通过文献调研,系统分析了生态环境损害鉴定中的生态效应评价指标与方法、损害鉴定路径。通过案例探讨,证实了所构建模型在科学评估污染物对生态系统服务价值方面的有效性,还为其他地区开展类似研究提供了方法借鉴和实践启示,具有重要的理论和应用价值。针对当前存在的问题,提出了在生态评价方法优化、技术体系完善、跨部门协同机制构建以及专业人才队伍建设等方面的改进建议。该论文提出的原则和对策,旨在提升生态评估的科学性与精准性,推动生态环境损害鉴定评估标准体系的完善,并为未来相关领域的研究提供参考。 展开更多
关键词 生态环境损害鉴定 生态效应评价 生态评价指标及方法 损害量化
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施硅对稻纵卷叶螟幼虫结苞危害的抑制作用及对水稻产量影响 被引量:2
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作者 程益宇 钟玉琪 +1 位作者 赵兰 侯茂林 《应用昆虫学报》 北大核心 2025年第3期607-618,共12页
【目的】探究田间施硅对稻纵卷叶螟Cnaphalocrocis medinalis幼虫结苞危害的控制作用及其对水稻产量的影响。【方法】设置品种和施硅水平双因素田间小区试验,品种为易感虫的台中1号(Taichung Native 1,TN1)和抗虫的中浙优8号(Zhongzheyo... 【目的】探究田间施硅对稻纵卷叶螟Cnaphalocrocis medinalis幼虫结苞危害的控制作用及其对水稻产量的影响。【方法】设置品种和施硅水平双因素田间小区试验,品种为易感虫的台中1号(Taichung Native 1,TN1)和抗虫的中浙优8号(Zhongzheyou 8,ZY8),施硅水平为0、150、300和600 kg SiO_(2)/hm^(2),测定稻纵卷叶螟幼虫在水稻分蘖期和孕穗期的结苞为害特征、孕穗期剑叶性状以及水稻产量相关指标。【结果】水稻成熟后土壤硅含量在品种间没有显著差异(P=0.910),但与不施硅对照相比,300和600 kg SiO_(2)/hm^(2)水平下土壤硅含量分别显著增加133.4%和182.4%(TN1,P≤0.030),以及154.9%和303.8%(ZY8,P≤0.005)。分蘖期水稻上稻纵卷叶螟叶苞的叶位和叶面分布特征在施硅水平之间有显著差异(P<0.001),施硅显著增大叶片正面结苞的频率(P<0.001)和叶苞丝束数量(P=0.020),分蘖期中浙优8号水稻上稻纵卷叶螟在叶片正面结苞的频率高于台中1号;不同施硅水平和品种下叶苞中的稻纵卷叶螟取食率和蛹重没有显著差异(P≥0.120)。孕穗期水稻上稻纵卷叶螟叶苞特征没有差异,但600kg SiO_(2)/hm^(2)水平硅处理显著降低幼虫取食率(P<0.001)、增加叶苞中丝束数量(P=0.002);剑叶理化性状受施硅影响,施硅显著降低剑叶的比叶面积、增加叶绿素相对含量和硅含量(P≤0.002)。此外,产量性状也与施硅有关,施硅显著增加中浙优8号的每穗总粒数、结实率和理论产量(P≤0.016)。不同施硅水平下,150 kg SiO_(2)/hm^(2)的理论收益最大。【结论】施硅能够改善水稻叶片的理化性质,增强叶片的韧性和光合作用,增强水稻对稻纵卷叶螟幼虫结苞为害的抵抗性和耐受性,并增加水稻理论产量,推荐田间施硅150 kg SiO_(2)/hm^(2)以获取较高收益。 展开更多
关键词 稻纵卷叶螟 结苞危害特征 剑叶理化性状 水稻产量指标
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