Although electrical stimulation is therapeutically applied for neural regeneration in patients, it remains unclear how electrical stimulation exerts its effects at the molecular level on spinal cord injury （SCI）. To...Although electrical stimulation is therapeutically applied for neural regeneration in patients, it remains unclear how electrical stimulation exerts its effects at the molecular level on spinal cord injury （SCI）. To identify the signaling pathway involved in electrical stimulation improving the function of injured spinal cord, 21 female Sprague-Dawley rats were randomly assigned to three groups： control （no surgical intervention, n = 6）, SCI （SCI only, n = 5）, and electrical simulation （ES; SCI induction followed by ES treatment, n = 10）. A complete spinal cord transection was performed at the 10^th thoracic level. Electrical stimulation of the injured spinal cord region was applied for 4 hours per day for 7 days. On days 2 and 7 post SCI, the Touch-Test Sensory Evaluators and the Basso-Beattie-Bresnahan locomotor scale were used to evaluate rat sensory and motor function. Somatosensory-evoked potentials of the tibial nerve of a hind paw of the rat were measured to evaluate the electrophysiological function of injured spinal cord. Western blot analysis was performed to measure p38-RhoA and ERK1/2-Bcl-2 pathways related protein levels in the injured spinal cord. Rat sensory and motor functions were similar between SCI and ES groups. Com- pared with the SCI group, in the ES group, the latencies of the somatosensory-evoked potential of the tibial nerve of rats were significantly shortened, the amplitudes were significantly increased, RhoA protein level was significantly decreased, protein gene product 9.5 expression, ERK1/2, p38, and Bcl-2 protein levels in the spinal cord were significantly increased. These data suggest that ES can promote the recovery of electrophysiological function of the injured spinal cord through regulating p38-RhoA and ERK1/2-Bcl-2 pathway-related protein levels in the injured spinal cord.展开更多
The technique of organic exhaust gas decomposition with impulse corono dischrge plasma has been investigated in this study. It has been discovered that the impulse electric field affected the decomposition efficiency ...The technique of organic exhaust gas decomposition with impulse corono dischrge plasma has been investigated in this study. It has been discovered that the impulse electric field affected the decomposition efficiency with the secondary electron emission coefficient (δ) of the corona electrode as an intermediary: when the impulse voltage power ( W ) was fixed the corona electrode material with higher δ could induce higher decomposition efficiency. In these experiments, wolfram electrode which has the highest δ has really induced the highest decomposition efficiency.展开更多
Ultraviolet(UV)light,invisible to the human eye,possesses both benefits and risks.To harness its potential,UV photodetectors(PDs)have been engineered.These devices can convert UV photons into detectable signals,such a...Ultraviolet(UV)light,invisible to the human eye,possesses both benefits and risks.To harness its potential,UV photodetectors(PDs)have been engineered.These devices can convert UV photons into detectable signals,such as electrical impulses or visible light,enabling their application in diverse fields like environmental monitoring,healthcare,and aerospace.Wide bandgap semiconductors,with their high-efficiency UV light absorption and stable opto-electronic properties,stand out as ideal materials for UV PDs.This review comprehensively summarizes recent advancements in both traditional and emerging wide bandgap-based UV PDs,highlighting their roles in UV imaging,communication,and alarming.Moreover,it examines methods employed to enhance UV PD performance,delving into the advantages,challenges,and future research prospects in this area.By doing so,this review aims to spark innovation and guide the future development and application of UV PDs.展开更多
基金supported by a grant from Wonkwang Institute of Clinical Medicine in 2011
文摘Although electrical stimulation is therapeutically applied for neural regeneration in patients, it remains unclear how electrical stimulation exerts its effects at the molecular level on spinal cord injury （SCI）. To identify the signaling pathway involved in electrical stimulation improving the function of injured spinal cord, 21 female Sprague-Dawley rats were randomly assigned to three groups： control （no surgical intervention, n = 6）, SCI （SCI only, n = 5）, and electrical simulation （ES; SCI induction followed by ES treatment, n = 10）. A complete spinal cord transection was performed at the 10^th thoracic level. Electrical stimulation of the injured spinal cord region was applied for 4 hours per day for 7 days. On days 2 and 7 post SCI, the Touch-Test Sensory Evaluators and the Basso-Beattie-Bresnahan locomotor scale were used to evaluate rat sensory and motor function. Somatosensory-evoked potentials of the tibial nerve of a hind paw of the rat were measured to evaluate the electrophysiological function of injured spinal cord. Western blot analysis was performed to measure p38-RhoA and ERK1/2-Bcl-2 pathways related protein levels in the injured spinal cord. Rat sensory and motor functions were similar between SCI and ES groups. Com- pared with the SCI group, in the ES group, the latencies of the somatosensory-evoked potential of the tibial nerve of rats were significantly shortened, the amplitudes were significantly increased, RhoA protein level was significantly decreased, protein gene product 9.5 expression, ERK1/2, p38, and Bcl-2 protein levels in the spinal cord were significantly increased. These data suggest that ES can promote the recovery of electrophysiological function of the injured spinal cord through regulating p38-RhoA and ERK1/2-Bcl-2 pathway-related protein levels in the injured spinal cord.
文摘The technique of organic exhaust gas decomposition with impulse corono dischrge plasma has been investigated in this study. It has been discovered that the impulse electric field affected the decomposition efficiency with the secondary electron emission coefficient (δ) of the corona electrode as an intermediary: when the impulse voltage power ( W ) was fixed the corona electrode material with higher δ could induce higher decomposition efficiency. In these experiments, wolfram electrode which has the highest δ has really induced the highest decomposition efficiency.
基金supported by the Natural Science Research Start-up Foundation of Recruiting Talents and the Project of State Key Laboratory of Organic Electronics and Information Displays of Nanjing University of Posts and Telecommunication(nos.NY223177,NY221005,NY223179,and GZR2024010026)National Natural Science Foundation of China(62374091)the Special Professor Fund of Jiangsu Province(RK030STP21007).
文摘Ultraviolet(UV)light,invisible to the human eye,possesses both benefits and risks.To harness its potential,UV photodetectors(PDs)have been engineered.These devices can convert UV photons into detectable signals,such as electrical impulses or visible light,enabling their application in diverse fields like environmental monitoring,healthcare,and aerospace.Wide bandgap semiconductors,with their high-efficiency UV light absorption and stable opto-electronic properties,stand out as ideal materials for UV PDs.This review comprehensively summarizes recent advancements in both traditional and emerging wide bandgap-based UV PDs,highlighting their roles in UV imaging,communication,and alarming.Moreover,it examines methods employed to enhance UV PD performance,delving into the advantages,challenges,and future research prospects in this area.By doing so,this review aims to spark innovation and guide the future development and application of UV PDs.
