OBJECTIVE: To investigate the effectiveness of Shoushen granule,Chinese herbal preparation,on carotid artery elasticity in patients with carotid atherosclerosis.METHODS: The total of 156 carotid atherosclerosis patien...OBJECTIVE: To investigate the effectiveness of Shoushen granule,Chinese herbal preparation,on carotid artery elasticity in patients with carotid atherosclerosis.METHODS: The total of 156 carotid atherosclerosis patients were randomly divided into the intervention group(83 cases,treated with Shoushen granule) and the control group(73 cases,treated with pravastatin). Brachial-ankle pulse wave velocity(ba PWV) and Ankle-Brachial Pressure Index(ABI)were measured by automated arteriosclerosis detector. The changes of common carotid artery intima-media thickness(IMT) and parameters of the carotid artery elasticity in patients,including stiffness parameter(β),pressure-strain elastic modulus(Ep),arterial compliance(Ac),augmentation index(AI),and pulse wave velocity β(PWVβ) were detected by Echo-Tracking(ET) technique before and after 24 week treatment. In the meantime,levels of blood lipid,and liver and renal function were measured respectively.RESULTS: After 24 weeks,ba PWV,IMT and parameters of the carotid artery elasticity(β,Ep,AI and PWVβ) were markedly decreased in intervention group compared with those of before treatment(P < 0.01),but the level of Ac was increased significantly(P < 0.01). And there were no significant differences compared with control group on the same period(P > 0.05).CONCLUSION: In this pilot study,it was demonstrated ET technology and automated arteriosclerosis detector could be used to evaluate carotid artery elasticity effectively,and the action of Shoushen granule on carotid atherosclerosis might be related to the regulation of carotid artery elasticity.展开更多
Applying Lagrange-Germain＇s theory of elas- tic thin plates and Hamiltonian formulation, the dynamics of cantilever plates and the problem of its vibration control are studied, and a general solution is finally given...Applying Lagrange-Germain＇s theory of elas- tic thin plates and Hamiltonian formulation, the dynamics of cantilever plates and the problem of its vibration control are studied, and a general solution is finally given. Based on Hamiltonian and Lagrangian density function, we can obtain the flexural wave equation of the plate and the relationship between the transverse and the longitudinal eigenvalues. Based on eigenfunction expansion, dispersion equations of propagation mode of cantilever plates are deduced. By satisfying the boundary conditions of cantilever plates, the natural frequencies of the cantilever plate structure can be given. Then, analytic solution of the problem in plate structure is obtained. An hybrid wave/mode control approach, which is based on both independent modal space control and wave control methods, is described and adopted to analyze the active vibration control of cantilever plates. The low-order （controlled by modal control） and the high-order （controlled by wave control） frequency response of plates are both improved. The control spillover is avoided and the robustness of the system is also improved. Finally, simulation results are analyzed and discussed.展开更多
Traditional auto-scaling approaches are conceived as reactive automations,typically triggered when predefined thresholds are breached by resource consumption metrics.Managing such rules at scale is cumbersome,especial...Traditional auto-scaling approaches are conceived as reactive automations,typically triggered when predefined thresholds are breached by resource consumption metrics.Managing such rules at scale is cumbersome,especially when resources require non-negligible time to be instantiated.This paper introduces an architecture for predictive cloud operations,which enables orchestrators to apply time-series forecasting techniques to estimate the evolution of relevant metrics and take decisions based on the predicted state of the system.In this way,they can anticipate load peaks and trigger appropriate scaling actions in advance,such that new resources are available when needed.The proposed architecture is implemented in OpenStack,extending the monitoring capabilities of Monasca by injecting short-term forecasts of standard metrics.We use our architecture to implement predictive scaling policies leveraging on linear regression,autoregressive integrated moving average,feed-forward,and recurrent neural networks(RNN).Then,we evaluate their performance on a synthetic workload,comparing them to those of a traditional policy.To assess the ability of the different models to generalize to unseen patterns,we also evaluate them on traces from a real content delivery network(CDN)workload.In particular,the RNN model exhibites the best overall performance in terms of prediction error,observed client-side response latency,and forecasting overhead.The implementation of our architecture is open-source.展开更多
In this paper, we consider the partial differential equation of an elastic beam with structuraldamping by boundary feedback control. First, we prove this closed system is well--posed; then weestablish tbe exponential ...In this paper, we consider the partial differential equation of an elastic beam with structuraldamping by boundary feedback control. First, we prove this closed system is well--posed; then weestablish tbe exponential stability for this elastic system by using a theorem whichbelongs to F. L.Huang; finally, we discuss the distribution and multiplicity of the spectrum of this system. Theseresults are very important and useful in practical applications.展开更多
Influence of the elasticity of the base on vibration isolation performances of single layer, double layer and floating raft vibration isolation systems is investigated systematically. Characteristics of vibration coup...Influence of the elasticity of the base on vibration isolation performances of single layer, double layer and floating raft vibration isolation systems is investigated systematically. Characteristics of vibration coupling between different vibration isolation systems and different elastic bases are analyzed. Moreover the characteristics of vibration acceleration level difference and force transmissibility of different vibration isolation systems are discussed and their simpli- fled expressions are given. In addition the required control forces of active vibration isolation under different installations of actuators for different vibration isolation systems are compared. The results show that for all vibration isolation systems, the addition of the stiffness and damping of the base can enhance their vibration acceleration level difference and force transmissibility. Moreover for floating raft vibration isolation system, the addition of the stiffness and damping of the raft can enhance its vibration isolation performance and reduce the control force required bv active vibration isolation.展开更多
基金Supported by the National Natural Science Foundation of China(the Role of TLR4/My D88/NF-κB Signal Transduction Pathway and Expression of mi RNA-146a in Atherosclerosis and the Intervention Mechanism of Shen Invigorating Compounds,No.81202731Study on the mechanism of two-ways regulation of angiogenesis using Guanxin 1 from the VEGF-Ang cascade signaling pathway,No.81202664)+2 种基金General Program of Shanghai Municipal Health Bureau Foundation(Evaluation of the Clinical Effect of the Shoushen Granule in Patients with Atherosclerosis based on Echo-Tracking Technique,No.20114047Study on Biomarkers of Atherosclerosis based on Telomere,No.2010225)Traditional Chinese Medicine Foundation of Shanghai Municipal Health Bureau(Anti atherosclerosis Study of the Traditional Chinese Medicine Shoushen Granule on the Basis of Telomere,No.2010L046A)
文摘OBJECTIVE: To investigate the effectiveness of Shoushen granule,Chinese herbal preparation,on carotid artery elasticity in patients with carotid atherosclerosis.METHODS: The total of 156 carotid atherosclerosis patients were randomly divided into the intervention group(83 cases,treated with Shoushen granule) and the control group(73 cases,treated with pravastatin). Brachial-ankle pulse wave velocity(ba PWV) and Ankle-Brachial Pressure Index(ABI)were measured by automated arteriosclerosis detector. The changes of common carotid artery intima-media thickness(IMT) and parameters of the carotid artery elasticity in patients,including stiffness parameter(β),pressure-strain elastic modulus(Ep),arterial compliance(Ac),augmentation index(AI),and pulse wave velocity β(PWVβ) were detected by Echo-Tracking(ET) technique before and after 24 week treatment. In the meantime,levels of blood lipid,and liver and renal function were measured respectively.RESULTS: After 24 weeks,ba PWV,IMT and parameters of the carotid artery elasticity(β,Ep,AI and PWVβ) were markedly decreased in intervention group compared with those of before treatment(P < 0.01),but the level of Ac was increased significantly(P < 0.01). And there were no significant differences compared with control group on the same period(P > 0.05).CONCLUSION: In this pilot study,it was demonstrated ET technology and automated arteriosclerosis detector could be used to evaluate carotid artery elasticity effectively,and the action of Shoushen granule on carotid atherosclerosis might be related to the regulation of carotid artery elasticity.
基金supported by the National Natural Science Foundation of China(10572045)
文摘Applying Lagrange-Germain＇s theory of elas- tic thin plates and Hamiltonian formulation, the dynamics of cantilever plates and the problem of its vibration control are studied, and a general solution is finally given. Based on Hamiltonian and Lagrangian density function, we can obtain the flexural wave equation of the plate and the relationship between the transverse and the longitudinal eigenvalues. Based on eigenfunction expansion, dispersion equations of propagation mode of cantilever plates are deduced. By satisfying the boundary conditions of cantilever plates, the natural frequencies of the cantilever plate structure can be given. Then, analytic solution of the problem in plate structure is obtained. An hybrid wave/mode control approach, which is based on both independent modal space control and wave control methods, is described and adopted to analyze the active vibration control of cantilever plates. The low-order （controlled by modal control） and the high-order （controlled by wave control） frequency response of plates are both improved. The control spillover is avoided and the robustness of the system is also improved. Finally, simulation results are analyzed and discussed.
基金supported by the PNRR-M4C2-Investimento 1.3,Partenariato Esteso(No.PE00000013-FAIR).
文摘Traditional auto-scaling approaches are conceived as reactive automations,typically triggered when predefined thresholds are breached by resource consumption metrics.Managing such rules at scale is cumbersome,especially when resources require non-negligible time to be instantiated.This paper introduces an architecture for predictive cloud operations,which enables orchestrators to apply time-series forecasting techniques to estimate the evolution of relevant metrics and take decisions based on the predicted state of the system.In this way,they can anticipate load peaks and trigger appropriate scaling actions in advance,such that new resources are available when needed.The proposed architecture is implemented in OpenStack,extending the monitoring capabilities of Monasca by injecting short-term forecasts of standard metrics.We use our architecture to implement predictive scaling policies leveraging on linear regression,autoregressive integrated moving average,feed-forward,and recurrent neural networks(RNN).Then,we evaluate their performance on a synthetic workload,comparing them to those of a traditional policy.To assess the ability of the different models to generalize to unseen patterns,we also evaluate them on traces from a real content delivery network(CDN)workload.In particular,the RNN model exhibites the best overall performance in terms of prediction error,observed client-side response latency,and forecasting overhead.The implementation of our architecture is open-source.
文摘In this paper, we consider the partial differential equation of an elastic beam with structuraldamping by boundary feedback control. First, we prove this closed system is well--posed; then weestablish tbe exponential stability for this elastic system by using a theorem whichbelongs to F. L.Huang; finally, we discuss the distribution and multiplicity of the spectrum of this system. Theseresults are very important and useful in practical applications.
文摘Influence of the elasticity of the base on vibration isolation performances of single layer, double layer and floating raft vibration isolation systems is investigated systematically. Characteristics of vibration coupling between different vibration isolation systems and different elastic bases are analyzed. Moreover the characteristics of vibration acceleration level difference and force transmissibility of different vibration isolation systems are discussed and their simpli- fled expressions are given. In addition the required control forces of active vibration isolation under different installations of actuators for different vibration isolation systems are compared. The results show that for all vibration isolation systems, the addition of the stiffness and damping of the base can enhance their vibration acceleration level difference and force transmissibility. Moreover for floating raft vibration isolation system, the addition of the stiffness and damping of the raft can enhance its vibration isolation performance and reduce the control force required bv active vibration isolation.
