Allogeneic hematopoietic stem cell transplantation is one of the most important curative therapeutic methods for hematologic malignancies and certain non-malignant hematopoietic disorders.1-3 Despite advancements in p...Allogeneic hematopoietic stem cell transplantation is one of the most important curative therapeutic methods for hematologic malignancies and certain non-malignant hematopoietic disorders.1-3 Despite advancements in prophylactic strategies(eg,antithymocyte globulin or post-transplant cyclophosphamide),severe acute graft-versus-host disease(aGVHD),particularly the steroid refractory(SR)aGVHD,remains the important cause of early transplant-related mortality.展开更多
文摘Allogeneic hematopoietic stem cell transplantation is one of the most important curative therapeutic methods for hematologic malignancies and certain non-malignant hematopoietic disorders.1-3 Despite advancements in prophylactic strategies(eg,antithymocyte globulin or post-transplant cyclophosphamide),severe acute graft-versus-host disease(aGVHD),particularly the steroid refractory(SR)aGVHD,remains the important cause of early transplant-related mortality.