Although the fracture behavior of sea urchin spines has been extensively investigated,there is as yet a lack of quantitative estimation on the effect of growth rings on the fracture properties of sea urchin spines.In ...Although the fracture behavior of sea urchin spines has been extensively investigated,there is as yet a lack of quantitative estimation on the effect of growth rings on the fracture properties of sea urchin spines.In sea urchin spines,much denser pores present in growth rings rather than porous layers.The tensile strength and fracture toughness of sea urchin spine samples with different numbers of growth rings are measured by the Boundary Effect Model(BEM).The experimental results of single-edge notched three-point bending tests indicate that the BEM is an appropriate method to estimate the fracture toughness of the present porous sea urchin spines,and the number of growth rings plays an important role in the fracture properties of spines.Specifically,the tensile strength and fracture toughness of sea urchin spines can be significantly improved with the increase in the number of growth rings,and their fracture toughness can even reach a relatively high value compared with some other porous materials with an identical porosity.The present research findings are expected to provide a fundamental insight into the design of high-performance bionic materials with a highly porous structure.展开更多
Taking into account the startup behaviour of following vehicles in the waiting area of urban traffic signal, we propose an extended Nagel-Schreckenberg model for single-lane traffic flow, in which the dynamic behavior...Taking into account the startup behaviour of following vehicles in the waiting area of urban traffic signal, we propose an extended Nagel-Schreckenberg model for single-lane traffic flow, in which the dynamic behavior of each vehicle depends on not only its own headway but also the headway of the immediately preceding one. The numerical simulation of the present model reproduces some complicated nonlinear phenomena observed in real traffic such as free flow, ghostly blockage, synchronized flow and so on. For specific parameter combinations the flow-density relation of this model shows two meta-stable branches near the transition density from free flow to wide moving traffic jam. Finally, the analytical results of the model under some specific parameters are given by using the mean field theory.展开更多
DNA microarray technology is an extremely effective technique for studying gene expression patterns in cells, and the main challenge currently faced by this technology is how to analyze the large amount of gene expres...DNA microarray technology is an extremely effective technique for studying gene expression patterns in cells, and the main challenge currently faced by this technology is how to analyze the large amount of gene expression data generated. To address this, this paper employs a mixed-effects model to analyze gene expression data. In terms of data selection, 1176 genes from the white mouse gene expression dataset under two experimental conditions were chosen, setting up two conditions: pneumococcal infection and no infection, and constructing a mixed-effects model. After preprocessing the gene chip information, the data were imported into the model, preliminary results were calculated, and permutation tests were performed to biologically validate the preliminary results using GSEA. The final dataset consists of 20 groups of gene expression data from pneumococcal infection, which categorizes functionally related genes based on the similarity of their expression profiles, facilitating the study of genes with unknown functions.展开更多
The present article provides supplementary information of previous works of analytic models for predicting conductivity enhancements of carbon nanotube composites. The models, though fairly simple, are able to take ac...The present article provides supplementary information of previous works of analytic models for predicting conductivity enhancements of carbon nanotube composites. The models, though fairly simple, are able to take account of the effects of conductivity anisotropy, nonstraightness, and aspect ratio of the CNT additives on the conductivity enhancement of the composite and to give predictions agreeing well with existing experimental data. The omitted detailed derivation of this model is demonstrated in the present article with a more systematical analysis, which may help with further development in this direction. Furthermore, the effects of various orientation distributions of CNTs are reported here for the first time. The information may be useful in design or fabrication technology of CNT composites for better or specified conductivities.展开更多
Objective:This study aims to investigate the energy conduction mechanism of holmium laser lithotripsy based on the Gemini platform and validate the optimal lithotripsy parameters under this mechanism using an in vitro...Objective:This study aims to investigate the energy conduction mechanism of holmium laser lithotripsy based on the Gemini platform and validate the optimal lithotripsy parameters under this mechanism using an in vitro ureteral model.Methods:The Lumenis VersaPulse PowerSuite dual-wavelength laser system was employed,with a holmium laser wavelength of 2.1μm,power output of 0-80 W,pulse energy ranging from 0.2 to 3.5 J,and pulse frequency from 5 to 40 Hz.An in vitro thermal effect model of the holmium laser was established to simulate temperature changes in urinary stones under varying power levels,energy ranges,pulse frequencies,and irrigation rates.High-speed cameras and thermal imaging devices were used to observe and record the temperature of the stone and surrounding tissues during laser irradiation.Finite element analysis was integrated to simulate the energy conduction pathways of the holmium laser within the stone and ureteral wall,assessing whether localized high-temperature regions exceeded the thermal injury threshold.Results:Temperature in the stone fragmentation mode decreased significantly with increasing distance from the basket and higher irrigation rates,thereby reducing the risk of thermal injury.In fragmentation mode,both 276μm and 500μm core-diameter fibers generated significantly higher temperatures at the basket site compared to the free-running mode(P<0.05).No thermal injury was observed at irrigation rates≥15 ml/min across all parameter combinations;at 10 ml/min,only high-energy settings(3.5 J)approached the thermal injury threshold(50.3℃);at≤5 ml/min,high-energy settings(>1.5 J)consistently exceeded the danger threshold.The safest parameter combination was 0.5 J+5 Hz(at any irrigation rate).Within 5 min,temperatures at the stone surface-below,middle,and above the basket-reached 151.0℃±1.0℃,62.5℃±0.2℃,and 46.8℃±0.2℃,respectively,whereas the maximum temperature on the ureteral wall surface was only 49.5℃.The FEA results closely matched experimental observations,indicating that with 0.5 J+5 Hz(at any flow rate),laser energy is primarily confined within the stone,generating localized high-temperature zones(80℃-90℃)at the stone-ureter wall interface,which promotes stone fragmentation while effectively minimizing collateral tissue damage.Conclusion:The holmium laser energy conduction mechanism based on the Gemini platform is predominantly concentrated within the stone,exhibiting excellent directionality and depth penetration,enabling efficient lithotripsy while minimizing thermal damage to surrounding tissues.展开更多
Bayes decision rule of variance components for one-way random effects model is derived and empirical Bayes (EB) decision rules are constructed by kernel estimation method. Under suitable conditions, it is shown that t...Bayes decision rule of variance components for one-way random effects model is derived and empirical Bayes (EB) decision rules are constructed by kernel estimation method. Under suitable conditions, it is shown that the proposed EB decision rules are asymptotically optimal with convergence rates near O(n-1/2). Finally, an example concerning the main result is given.展开更多
The Portevin-Le Chatelier (PLC) effect means serrated yielding or jerky flow phenomenon in some alloys. In this paper a macroscopic model is developed to investigate the PLC effect with the emphasis on mechanical resp...The Portevin-Le Chatelier (PLC) effect means serrated yielding or jerky flow phenomenon in some alloys. In this paper a macroscopic model is developed to investigate the PLC effect with the emphasis on mechanical response of the structure evolution on microscopic scale. In addition to the normal work hardening effect, the model takes account of the thermal activation of dislocation moving with the aid of stress and the collective interactions between mobile dislocations and solute atoms due to dynamic strain ageing (DSA). It can satisfy the negative strain rate sensitivity of flow stress, which is believed to be one of the most special features associated with the PLC effect. The heterogeneous nature of the deformed material is also considered by introducing a nonuniform spatial distribution of some model parameters. The serrated yielding and localized deformation behavior can be successfully reproduced via numerical simulation based on this model.展开更多
Korean larch(Larix olgensis)is one of the main tree species for aff orestation and timber production in northeast China.However,its timber quality and growth ability are largely infl uenced by crown size,structure and...Korean larch(Larix olgensis)is one of the main tree species for aff orestation and timber production in northeast China.However,its timber quality and growth ability are largely infl uenced by crown size,structure and shape.The majority of crown models are static models based on tree size and stand characteristics from temporary sample plots,but crown dynamic models has seldom been constructed.Therefore,this study aimed to develop height to crown base(HCB)and crown length(CL)dynamic models using the branch mortality technique for a Korean larch plantation.The nonlinear mixed-eff ects model with random eff ects,variance functions and correlation structures,was used to build HCB and CL dynamic models.The data were obtained from 95 sample trees of 19 plots in Meng JiaGang forest farm in Northeast China.The results showed that HCB progressively increases as tree age,tree height growth(HT growth)and diameter at breast height growth(DBH growth).The CL was increased with tree age in 20 years ago,and subsequently stabilized.HT growth,DBH growth stand basal area(BAS)and crown competition factor(CCF)signifi cantly infl uenced HCB and CL.The HCB was positively correlated with BAS,HT growth and DBH growth,but negatively correlated with CCF.The CL was positively correlated with BAS and CCF,but negatively correlated with DBH growth.Model fi tting and validation confi rmed that the mixed-eff ects model considering the stand and tree level random eff ects was accurate and reliable for predicting the HCB and CL dynamics.However,the models involving adding variance functions and time series correlation structure could not completely remove heterogeneity and autocorrelation,and the fi tting precision of the models was reduced.Therefore,from the point of view of application,we should take care to avoid setting up over-complex models.The HCB and CL dynamic models in our study may also be incorporated into stand growth and yield model systems in China.展开更多
Physical mechanisms and influencing factors on the effective stress coefficient for rock/soil-like porous materials are investigated, based on which equivalent connectivity index is proposed. The equivalent connectivi...Physical mechanisms and influencing factors on the effective stress coefficient for rock/soil-like porous materials are investigated, based on which equivalent connectivity index is proposed. The equivalent connectivity index, relying on the meso-scale structure of porous material and the property of liquid, denotes the connectivity of pores in Representative Element Area （REA）. If the conductivity of the porous material is anisotropic, the equivalent connectivity index is a second order tensor. Based on the basic theories of continuous mechanics and tensor analysis, relationship between area porosity and volumetric porosity of porous materials is deduced. Then a generalized expression, describing the relation between effective stress coefficient tensor and equivalent connectivity tensor of pores, is proposed, and the expression can be applied to isotropic media and also to anisotropic materials. Furthermore, evolution of porosity and equivalent connectivity index of the pore are studied in the strain space, and the method to determine the corresponding functions in expressions above is proposed using genetic algorithm and genetic programming. Two applications show that the results obtained by the method in this paper perfectly agree with the test data. This paper provides an important theoretical support to the coupled hydro-mechanical research.展开更多
The model of double-well Bose-Einstein condensates in the strong-interaction regime is shown to reduce adiabatically to an effective two-state model describing the Rabi oscillations between the two atomic Fock states ...The model of double-well Bose-Einstein condensates in the strong-interaction regime is shown to reduce adiabatically to an effective two-state model describing the Rabi oscillations between the two atomic Fock states ｜N, 0〉 and [0, N〉, and the NOON states of arbitrary ultracold atoms can therefore be generated periodically from the initial state of either one of the Foek states.展开更多
Through the differentiating and integrating process, a mathematical model for tempering time effect on quenched steel was derived based on the attribute of state function and the general equation of Hollomon parameter...Through the differentiating and integrating process, a mathematical model for tempering time effect on quenched steel was derived based on the attribute of state function and the general equation of Hollomon parameter, which correlates the tempering hardness with the tempering time at different tempering temperature. Using the established model, the linear relationship between the tempering hardness and the tempering time in logarithm was proved theoretically, and the tempering hardness for various tempering time was reduced to the measurement and calculation of a hardness experiment tempered for 1 h at different tempering temperatures. Moreover, the hardness of steel 42CrMo and T8Mn tempered for various times at 200-600℃ was calculated using this method. The predicted results are in good agreement with those of the available experiments.展开更多
Impacts of greenhouse effects (2 × CO2) upon climate change over China as simulated by a regional climate model over China (RegCM / China) have been investigated. The model was based on RegCM2 and was nested to a...Impacts of greenhouse effects (2 × CO2) upon climate change over China as simulated by a regional climate model over China (RegCM / China) have been investigated. The model was based on RegCM2 and was nested to a global coupled ocean-atmosphere model (CSIRO R21L9 AOGCM model). Results of the control run (1 × CO2) indicated that simulations of surface air temperature and precipitation in China by RegCM are much better than that by the global coupled model because of a higher resolution. Results of sensitive experiment by RegCM with 2 × CO2 showed that the surface air temperature over China might increase remarkably due to greenhouse effect, especially in winter season and in North China. Precipitation might also increase in most parts of China due to the CO2 doubling. Key words Regional climate model - Greenhouse effect This research was supported by National Key Programme for Developing Basic Sciences (G1998040900 — Part I), Chinese Academy of Sciences Key Program KZCX2-203 and KZ981-B1-108.展开更多
Objective:To investigate the analgesic and anti-inflammatory effects of the methanolic extract of the leaves of Triumfetta rhomboidea on mice and rats respectively.And to screen the phytochemical constituent of the ex...Objective:To investigate the analgesic and anti-inflammatory effects of the methanolic extract of the leaves of Triumfetta rhomboidea on mice and rats respectively.And to screen the phytochemical constituent of the extract. Methods:The analgesic effect was determined by acetic acid-induced writhing test in mice.While the anti-inflammatory activity was determined by egg albumin-induced oedema of the rat paw.Phytochemical screening was done by standard procedures.Results:Triumfetta rhomboidea leaf extract(50 -400 mg/kg) caused a statistically significant inhibition on the egg albumin-induced eodema or inflammation in Wister albino rats with P【0.001(ANOVA).This effect was higher than the observed effect with Piroxicam(0.5 mg/kg) which was used as a standard.The effect was also dose-dependent.Furthermore,Triumfetta rhomboidea extract caused a statistically significant reduction in the number of acetic acid-induced writhing in mice,with P【0.001(ANOVA).These effects were also does-dependent and greater than the analgesic effects by paracetamol which was used as a reference drug.Phytochemical screening revealed the presence of flavonoids,steroids, triterpenoids alkaloids,tannins and saponins in Truimfetta rhomboidea leaf extract.Conclusion:Triumfetta rhomboidea can be recommended for acute inflammatory disorders and diseases associated with pains.This also supports its traditional use as an anti-snake bite and anti-cancer or anti-tumor agent.Further study is on the way to find out the mechanism of its action and also to isolate,identify and characterize the active principle responsible for these effects in this plant.展开更多
The effects of three different typical resistivity models（Spitzer, Z＆L and M＆G） on the performance of pulsed inductive acceleration plasma are studied. Numerical results show that their influences decrease with th...The effects of three different typical resistivity models（Spitzer, Z＆L and M＆G） on the performance of pulsed inductive acceleration plasma are studied. Numerical results show that their influences decrease with the increase of the plasma temperature. The significant discriminations among them appear at the plasma temperature lower than 2.5 eV, and the maximum gap of the pulsed inductive plasma accelerated efficiency is approximately 2.5%.Moreover, the pulsed inductive plasma accelerated efficiency is absolutely related to the dynamic impedance parameters, such as voltage, inductance, capacitance and flow rate. However, the distribution of the efficiency as a function of plasma temperature with three resistivity models has nothing to do with the dynamic impedance parameter.展开更多
Diffusion has been systematically described as the main mechanism of chloride transport in reinforced concrete（RC） structure, especially when the concrete is in a saturated state. However, the single mechanism of di...Diffusion has been systematically described as the main mechanism of chloride transport in reinforced concrete（RC） structure, especially when the concrete is in a saturated state. However, the single mechanism of diffusion is not able to describe the actual chloride ingress in the nonsaturated concrete. Instead, it is dominated by the interaction of diffusion and convection. With the synergetic effects of various factors taken into account, this study aimed to modify and develop an analytical convection- diffusion coupling model for chloride transport in nonsaturated concrete. The model was verified by simulation of laboratory tests and field measurement. The results of comparison study demonstrate that the analytical model developed in this study is efficient and accurate in predicting the chloride profiles in the nonsaturated concrete.展开更多
A regional climate model(RegCM4.3.4) coupled with an aerosol-snow/ice feedback module was used to simulate the deposition of anthropogenic light-absorbing impurities in snow/ice and the potential radiative feedback of...A regional climate model(RegCM4.3.4) coupled with an aerosol-snow/ice feedback module was used to simulate the deposition of anthropogenic light-absorbing impurities in snow/ice and the potential radiative feedback of black carbon(BC) on temperature and snow cover over the Tibetan Plateau(TP) in 1990-2009. Two experiments driven by ERA-interim reanalysis were performed, i.e., with and without aerosol-snow/ice feedback. Results indicated that the total deposition BC and organic matter(OM) in snow/ice in the monsoon season(MayeS eptember) were much more than non-monsoon season(the remainder of the year). The great BC and OM deposition were simulated along the margin of the TP in the non-monsoon season, and the higher deposition values also occurred in the western TP than the other regions during the monsoon period. BC-in-snow/ice decreased surface albedo and caused positive surface radiative forcing(SRF)(3.0-4.5 W m^(-2)) over the western TP in the monsoon season. The maximum SRF(5-6 W m^(-2)) simulated in the Himalayas and southeastern TP in the non-monsoon season. The surface temperature increased by 0.1-1.5℃ and snow water equivalent decreased by 5-25 mm over the TP, which showed similar spatial distributions with the variations of SRF in each season. This study provided a useful tool to investigate the mechanisms involved in the effect of aerosols on climate change and the water cycle in the cryospheric environment of the TP.展开更多
Transcranial Hall-effect stimulation（THS） is a new stimulation method in which an ultrasonic wave in a static magnetic field generates an electric field in an area of interest such as in the brain to modulate neuron...Transcranial Hall-effect stimulation（THS） is a new stimulation method in which an ultrasonic wave in a static magnetic field generates an electric field in an area of interest such as in the brain to modulate neuronal activities. However, the biophysical basis of simulating the neurons remains unknown. To address this problem, we perform a theoretical analysis based on a passive cable model to investigate the THS mechanism of neurons. Nerve tissues are conductive; an ultrasonic wave can move ions embedded in the tissue in a static magnetic field to generate an electric field（due to Lorentz force）.In this study, a simulation model for an ultrasonically induced electric field in a static magnetic field is derived. Then,based on the passive cable model, the analytical solution for the voltage distribution in a nerve tissue is determined. The simulation results showthat THS can generate a voltage to stimulate neurons. Because the THS method possesses a higher spatial resolution and a deeper penetration depth, it shows promise as a tool for treating or rehabilitating neuropsychiatric disorders.展开更多
In this speculative analysis, our main focused is to address the neurotic condition that occurs due to accumulation of blood components on the wall of the artery that results in blood coagulation. Specifically, to per...In this speculative analysis, our main focused is to address the neurotic condition that occurs due to accumulation of blood components on the wall of the artery that results in blood coagulation. Specifically, to perceive this phenomena clot model is considered. To discuss this analysis mathematical model is formed in the presence of the effective thermal conductivity and variable viscosity of base fluid. Appropriate slip conditions are employed to obtain the close form solutions of temperature and velocity profile. The graphical illustrations have been presented for the assessment of pressure rise, pressure gradient and velocity profile. The effects of several parameters on the flow quantities for theoretical observation are investigated. At the end, the results confirmed that the impulsion of copper and silver nanoparticles as drug agent enlarges the amplitude of the velocity and hence nanoparticles play an important role in engineering and biomedical applications such as drug delivery system.展开更多
In this paper, a new current expression based on both the direct currect （DC） characteristics of the A1GaN/GaN high election mobility transistor （HEMT） and the hyperbolic tangent function tanh is proposed, by whic...In this paper, a new current expression based on both the direct currect （DC） characteristics of the A1GaN/GaN high election mobility transistor （HEMT） and the hyperbolic tangent function tanh is proposed, by which we can describe the kink effect of the A1GaN/GaN HEMT well. Then, an improved EEHEMT model including the proposed current expression is presented. The simulated and measured results of Ⅰ-Ⅴ, S-parameter, and radio frequency （RF） large-signal characteristics are compared for a self-developed on-wafer A1GaN/GaN HEMT with ten gate fingers each being 0.4-μm long and 125-p-m wide （Such an A1GaN/GaN HEMT is denoted as A1GaN/GaN HEMT （10 × 125 μm））. The improved large signal model simulates the Ⅰ-Ⅴ characteristic much more accurately than the original one, and its transconductance and RF characteristics are also in excellent agreement with the measured data.展开更多
基金This work was supported by the National Natural Science Foundation of China[Grant No.51902043]the Fundamental Research Funds for the Central Universities[Grant No.N2102007,and N2102002]。
文摘Although the fracture behavior of sea urchin spines has been extensively investigated,there is as yet a lack of quantitative estimation on the effect of growth rings on the fracture properties of sea urchin spines.In sea urchin spines,much denser pores present in growth rings rather than porous layers.The tensile strength and fracture toughness of sea urchin spine samples with different numbers of growth rings are measured by the Boundary Effect Model(BEM).The experimental results of single-edge notched three-point bending tests indicate that the BEM is an appropriate method to estimate the fracture toughness of the present porous sea urchin spines,and the number of growth rings plays an important role in the fracture properties of spines.Specifically,the tensile strength and fracture toughness of sea urchin spines can be significantly improved with the increase in the number of growth rings,and their fracture toughness can even reach a relatively high value compared with some other porous materials with an identical porosity.The present research findings are expected to provide a fundamental insight into the design of high-performance bionic materials with a highly porous structure.
文摘Taking into account the startup behaviour of following vehicles in the waiting area of urban traffic signal, we propose an extended Nagel-Schreckenberg model for single-lane traffic flow, in which the dynamic behavior of each vehicle depends on not only its own headway but also the headway of the immediately preceding one. The numerical simulation of the present model reproduces some complicated nonlinear phenomena observed in real traffic such as free flow, ghostly blockage, synchronized flow and so on. For specific parameter combinations the flow-density relation of this model shows two meta-stable branches near the transition density from free flow to wide moving traffic jam. Finally, the analytical results of the model under some specific parameters are given by using the mean field theory.
文摘DNA microarray technology is an extremely effective technique for studying gene expression patterns in cells, and the main challenge currently faced by this technology is how to analyze the large amount of gene expression data generated. To address this, this paper employs a mixed-effects model to analyze gene expression data. In terms of data selection, 1176 genes from the white mouse gene expression dataset under two experimental conditions were chosen, setting up two conditions: pneumococcal infection and no infection, and constructing a mixed-effects model. After preprocessing the gene chip information, the data were imported into the model, preliminary results were calculated, and permutation tests were performed to biologically validate the preliminary results using GSEA. The final dataset consists of 20 groups of gene expression data from pneumococcal infection, which categorizes functionally related genes based on the similarity of their expression profiles, facilitating the study of genes with unknown functions.
文摘The present article provides supplementary information of previous works of analytic models for predicting conductivity enhancements of carbon nanotube composites. The models, though fairly simple, are able to take account of the effects of conductivity anisotropy, nonstraightness, and aspect ratio of the CNT additives on the conductivity enhancement of the composite and to give predictions agreeing well with existing experimental data. The omitted detailed derivation of this model is demonstrated in the present article with a more systematical analysis, which may help with further development in this direction. Furthermore, the effects of various orientation distributions of CNTs are reported here for the first time. The information may be useful in design or fabrication technology of CNT composites for better or specified conductivities.
文摘Objective:This study aims to investigate the energy conduction mechanism of holmium laser lithotripsy based on the Gemini platform and validate the optimal lithotripsy parameters under this mechanism using an in vitro ureteral model.Methods:The Lumenis VersaPulse PowerSuite dual-wavelength laser system was employed,with a holmium laser wavelength of 2.1μm,power output of 0-80 W,pulse energy ranging from 0.2 to 3.5 J,and pulse frequency from 5 to 40 Hz.An in vitro thermal effect model of the holmium laser was established to simulate temperature changes in urinary stones under varying power levels,energy ranges,pulse frequencies,and irrigation rates.High-speed cameras and thermal imaging devices were used to observe and record the temperature of the stone and surrounding tissues during laser irradiation.Finite element analysis was integrated to simulate the energy conduction pathways of the holmium laser within the stone and ureteral wall,assessing whether localized high-temperature regions exceeded the thermal injury threshold.Results:Temperature in the stone fragmentation mode decreased significantly with increasing distance from the basket and higher irrigation rates,thereby reducing the risk of thermal injury.In fragmentation mode,both 276μm and 500μm core-diameter fibers generated significantly higher temperatures at the basket site compared to the free-running mode(P<0.05).No thermal injury was observed at irrigation rates≥15 ml/min across all parameter combinations;at 10 ml/min,only high-energy settings(3.5 J)approached the thermal injury threshold(50.3℃);at≤5 ml/min,high-energy settings(>1.5 J)consistently exceeded the danger threshold.The safest parameter combination was 0.5 J+5 Hz(at any irrigation rate).Within 5 min,temperatures at the stone surface-below,middle,and above the basket-reached 151.0℃±1.0℃,62.5℃±0.2℃,and 46.8℃±0.2℃,respectively,whereas the maximum temperature on the ureteral wall surface was only 49.5℃.The FEA results closely matched experimental observations,indicating that with 0.5 J+5 Hz(at any flow rate),laser energy is primarily confined within the stone,generating localized high-temperature zones(80℃-90℃)at the stone-ureter wall interface,which promotes stone fragmentation while effectively minimizing collateral tissue damage.Conclusion:The holmium laser energy conduction mechanism based on the Gemini platform is predominantly concentrated within the stone,exhibiting excellent directionality and depth penetration,enabling efficient lithotripsy while minimizing thermal damage to surrounding tissues.
基金The project is partly supported by NSFC (19971085)the Doctoral Program Foundation of the Institute of High Education and the Special Foundation of Chinese Academy of Sciences.
文摘Bayes decision rule of variance components for one-way random effects model is derived and empirical Bayes (EB) decision rules are constructed by kernel estimation method. Under suitable conditions, it is shown that the proposed EB decision rules are asymptotically optimal with convergence rates near O(n-1/2). Finally, an example concerning the main result is given.
基金This work was supported by the National Natural Seience Foundation of China under gran No.10372098 and 10232030.We would also like to thank the Lab of Mechanical&Materials Science of USTC for their help in the experiments on MTS
文摘The Portevin-Le Chatelier (PLC) effect means serrated yielding or jerky flow phenomenon in some alloys. In this paper a macroscopic model is developed to investigate the PLC effect with the emphasis on mechanical response of the structure evolution on microscopic scale. In addition to the normal work hardening effect, the model takes account of the thermal activation of dislocation moving with the aid of stress and the collective interactions between mobile dislocations and solute atoms due to dynamic strain ageing (DSA). It can satisfy the negative strain rate sensitivity of flow stress, which is believed to be one of the most special features associated with the PLC effect. The heterogeneous nature of the deformed material is also considered by introducing a nonuniform spatial distribution of some model parameters. The serrated yielding and localized deformation behavior can be successfully reproduced via numerical simulation based on this model.
基金supported by the National Key Research and Development Program of China(2017YFD0600401)the Fundamental Research Funds for the Central Universities(2572019CP08)
文摘Korean larch(Larix olgensis)is one of the main tree species for aff orestation and timber production in northeast China.However,its timber quality and growth ability are largely infl uenced by crown size,structure and shape.The majority of crown models are static models based on tree size and stand characteristics from temporary sample plots,but crown dynamic models has seldom been constructed.Therefore,this study aimed to develop height to crown base(HCB)and crown length(CL)dynamic models using the branch mortality technique for a Korean larch plantation.The nonlinear mixed-eff ects model with random eff ects,variance functions and correlation structures,was used to build HCB and CL dynamic models.The data were obtained from 95 sample trees of 19 plots in Meng JiaGang forest farm in Northeast China.The results showed that HCB progressively increases as tree age,tree height growth(HT growth)and diameter at breast height growth(DBH growth).The CL was increased with tree age in 20 years ago,and subsequently stabilized.HT growth,DBH growth stand basal area(BAS)and crown competition factor(CCF)signifi cantly infl uenced HCB and CL.The HCB was positively correlated with BAS,HT growth and DBH growth,but negatively correlated with CCF.The CL was positively correlated with BAS and CCF,but negatively correlated with DBH growth.Model fi tting and validation confi rmed that the mixed-eff ects model considering the stand and tree level random eff ects was accurate and reliable for predicting the HCB and CL dynamics.However,the models involving adding variance functions and time series correlation structure could not completely remove heterogeneity and autocorrelation,and the fi tting precision of the models was reduced.Therefore,from the point of view of application,we should take care to avoid setting up over-complex models.The HCB and CL dynamic models in our study may also be incorporated into stand growth and yield model systems in China.
基金supported by the Yalongjiang River Joint Fund by the National Natural Science Foundation of China(NSFC)Ertan Hydropower Development Company,LTD(Nos.50579091 and 50539090)+1 种基金NSFC(No.10772190)Major State Basic Research Project of China(No.2002CB412708)
文摘Physical mechanisms and influencing factors on the effective stress coefficient for rock/soil-like porous materials are investigated, based on which equivalent connectivity index is proposed. The equivalent connectivity index, relying on the meso-scale structure of porous material and the property of liquid, denotes the connectivity of pores in Representative Element Area （REA）. If the conductivity of the porous material is anisotropic, the equivalent connectivity index is a second order tensor. Based on the basic theories of continuous mechanics and tensor analysis, relationship between area porosity and volumetric porosity of porous materials is deduced. Then a generalized expression, describing the relation between effective stress coefficient tensor and equivalent connectivity tensor of pores, is proposed, and the expression can be applied to isotropic media and also to anisotropic materials. Furthermore, evolution of porosity and equivalent connectivity index of the pore are studied in the strain space, and the method to determine the corresponding functions in expressions above is proposed using genetic algorithm and genetic programming. Two applications show that the results obtained by the method in this paper perfectly agree with the test data. This paper provides an important theoretical support to the coupled hydro-mechanical research.
基金Supported in part by the National Natural Science Foundation of China under Grant Nos.60478029,10575040,10634060,and 90503010the National Fundamental Research Program of China under Grant No.2005CB724508
文摘The model of double-well Bose-Einstein condensates in the strong-interaction regime is shown to reduce adiabatically to an effective two-state model describing the Rabi oscillations between the two atomic Fock states ｜N, 0〉 and [0, N〉, and the NOON states of arbitrary ultracold atoms can therefore be generated periodically from the initial state of either one of the Foek states.
文摘Through the differentiating and integrating process, a mathematical model for tempering time effect on quenched steel was derived based on the attribute of state function and the general equation of Hollomon parameter, which correlates the tempering hardness with the tempering time at different tempering temperature. Using the established model, the linear relationship between the tempering hardness and the tempering time in logarithm was proved theoretically, and the tempering hardness for various tempering time was reduced to the measurement and calculation of a hardness experiment tempered for 1 h at different tempering temperatures. Moreover, the hardness of steel 42CrMo and T8Mn tempered for various times at 200-600℃ was calculated using this method. The predicted results are in good agreement with those of the available experiments.
基金This research was supported by National Key Programme for Developing Basic Sciences(G1998040900 - Part I) Chinese Academy of
文摘Impacts of greenhouse effects (2 × CO2) upon climate change over China as simulated by a regional climate model over China (RegCM / China) have been investigated. The model was based on RegCM2 and was nested to a global coupled ocean-atmosphere model (CSIRO R21L9 AOGCM model). Results of the control run (1 × CO2) indicated that simulations of surface air temperature and precipitation in China by RegCM are much better than that by the global coupled model because of a higher resolution. Results of sensitive experiment by RegCM with 2 × CO2 showed that the surface air temperature over China might increase remarkably due to greenhouse effect, especially in winter season and in North China. Precipitation might also increase in most parts of China due to the CO2 doubling. Key words Regional climate model - Greenhouse effect This research was supported by National Key Programme for Developing Basic Sciences (G1998040900 — Part I), Chinese Academy of Sciences Key Program KZCX2-203 and KZ981-B1-108.
文摘Objective:To investigate the analgesic and anti-inflammatory effects of the methanolic extract of the leaves of Triumfetta rhomboidea on mice and rats respectively.And to screen the phytochemical constituent of the extract. Methods:The analgesic effect was determined by acetic acid-induced writhing test in mice.While the anti-inflammatory activity was determined by egg albumin-induced oedema of the rat paw.Phytochemical screening was done by standard procedures.Results:Triumfetta rhomboidea leaf extract(50 -400 mg/kg) caused a statistically significant inhibition on the egg albumin-induced eodema or inflammation in Wister albino rats with P【0.001(ANOVA).This effect was higher than the observed effect with Piroxicam(0.5 mg/kg) which was used as a standard.The effect was also dose-dependent.Furthermore,Triumfetta rhomboidea extract caused a statistically significant reduction in the number of acetic acid-induced writhing in mice,with P【0.001(ANOVA).These effects were also does-dependent and greater than the analgesic effects by paracetamol which was used as a reference drug.Phytochemical screening revealed the presence of flavonoids,steroids, triterpenoids alkaloids,tannins and saponins in Truimfetta rhomboidea leaf extract.Conclusion:Triumfetta rhomboidea can be recommended for acute inflammatory disorders and diseases associated with pains.This also supports its traditional use as an anti-snake bite and anti-cancer or anti-tumor agent.Further study is on the way to find out the mechanism of its action and also to isolate,identify and characterize the active principle responsible for these effects in this plant.
基金Supported by the Fund of Science and Technology on Vacuum Technology and Physics Laboratory of Lanzhou Institute of Physics under Grant No YSC0715the National Natural Science Foundation of China under Grant No 62601210the Civil Aerospace Technology Research Project under Grant No D010509
文摘The effects of three different typical resistivity models（Spitzer, Z＆L and M＆G） on the performance of pulsed inductive acceleration plasma are studied. Numerical results show that their influences decrease with the increase of the plasma temperature. The significant discriminations among them appear at the plasma temperature lower than 2.5 eV, and the maximum gap of the pulsed inductive plasma accelerated efficiency is approximately 2.5%.Moreover, the pulsed inductive plasma accelerated efficiency is absolutely related to the dynamic impedance parameters, such as voltage, inductance, capacitance and flow rate. However, the distribution of the efficiency as a function of plasma temperature with three resistivity models has nothing to do with the dynamic impedance parameter.
基金Funded by the National Natural Science Foundation of China(Nos.51278304,U1134209,U1434204&51422814)the National Basic Research Program(973 Program)of China(No.011-CB013604)the Technology Research and Development Program(Basic Research Project)of Shenzhen(Nos.JCYJ20120613174456685&JCYJ20130329143859418)
文摘Diffusion has been systematically described as the main mechanism of chloride transport in reinforced concrete（RC） structure, especially when the concrete is in a saturated state. However, the single mechanism of diffusion is not able to describe the actual chloride ingress in the nonsaturated concrete. Instead, it is dominated by the interaction of diffusion and convection. With the synergetic effects of various factors taken into account, this study aimed to modify and develop an analytical convection- diffusion coupling model for chloride transport in nonsaturated concrete. The model was verified by simulation of laboratory tests and field measurement. The results of comparison study demonstrate that the analytical model developed in this study is efficient and accurate in predicting the chloride profiles in the nonsaturated concrete.
基金supported by National Nature Science Foundation of China (41301061)Chinese Academy of Sciences (KJZD-EW-G03-04)China Meteorological Administration Special Public Welfare Research Fund (GYHY201306019)
文摘A regional climate model(RegCM4.3.4) coupled with an aerosol-snow/ice feedback module was used to simulate the deposition of anthropogenic light-absorbing impurities in snow/ice and the potential radiative feedback of black carbon(BC) on temperature and snow cover over the Tibetan Plateau(TP) in 1990-2009. Two experiments driven by ERA-interim reanalysis were performed, i.e., with and without aerosol-snow/ice feedback. Results indicated that the total deposition BC and organic matter(OM) in snow/ice in the monsoon season(MayeS eptember) were much more than non-monsoon season(the remainder of the year). The great BC and OM deposition were simulated along the margin of the TP in the non-monsoon season, and the higher deposition values also occurred in the western TP than the other regions during the monsoon period. BC-in-snow/ice decreased surface albedo and caused positive surface radiative forcing(SRF)(3.0-4.5 W m^(-2)) over the western TP in the monsoon season. The maximum SRF(5-6 W m^(-2)) simulated in the Himalayas and southeastern TP in the non-monsoon season. The surface temperature increased by 0.1-1.5℃ and snow water equivalent decreased by 5-25 mm over the TP, which showed similar spatial distributions with the variations of SRF in each season. This study provided a useful tool to investigate the mechanisms involved in the effect of aerosols on climate change and the water cycle in the cryospheric environment of the TP.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61273063 and 61503321)the China Postdoctoral Science Foundation(Grant No.2013M540215)+1 种基金the Natural Science Foundation of Hebei Province,China(Grant No.F2014203161)the Youth Research Program of Yanshan University,China(Grant No.02000134)
文摘Transcranial Hall-effect stimulation（THS） is a new stimulation method in which an ultrasonic wave in a static magnetic field generates an electric field in an area of interest such as in the brain to modulate neuronal activities. However, the biophysical basis of simulating the neurons remains unknown. To address this problem, we perform a theoretical analysis based on a passive cable model to investigate the THS mechanism of neurons. Nerve tissues are conductive; an ultrasonic wave can move ions embedded in the tissue in a static magnetic field to generate an electric field（due to Lorentz force）.In this study, a simulation model for an ultrasonically induced electric field in a static magnetic field is derived. Then,based on the passive cable model, the analytical solution for the voltage distribution in a nerve tissue is determined. The simulation results showthat THS can generate a voltage to stimulate neurons. Because the THS method possesses a higher spatial resolution and a deeper penetration depth, it shows promise as a tool for treating or rehabilitating neuropsychiatric disorders.
基金the Higher Education Commission, Pakistan (HEC) for the financial support to complete this work under the research Grant No. 6170/Federal/NRPU/R&D/HEC/2016
文摘In this speculative analysis, our main focused is to address the neurotic condition that occurs due to accumulation of blood components on the wall of the artery that results in blood coagulation. Specifically, to perceive this phenomena clot model is considered. To discuss this analysis mathematical model is formed in the presence of the effective thermal conductivity and variable viscosity of base fluid. Appropriate slip conditions are employed to obtain the close form solutions of temperature and velocity profile. The graphical illustrations have been presented for the assessment of pressure rise, pressure gradient and velocity profile. The effects of several parameters on the flow quantities for theoretical observation are investigated. At the end, the results confirmed that the impulsion of copper and silver nanoparticles as drug agent enlarges the amplitude of the velocity and hence nanoparticles play an important role in engineering and biomedical applications such as drug delivery system.
基金Project supported by the National Natural Science Foundation of China(Grant No.61334002)the Opening Project of Science and Technology on Reliability Physics and Application Technology of Electronic Component Laboratory(Grant No.ZHD201206)the Program for New Century Excellent Talents in University(Grant No.NCET-12-0915)
文摘In this paper, a new current expression based on both the direct currect （DC） characteristics of the A1GaN/GaN high election mobility transistor （HEMT） and the hyperbolic tangent function tanh is proposed, by which we can describe the kink effect of the A1GaN/GaN HEMT well. Then, an improved EEHEMT model including the proposed current expression is presented. The simulated and measured results of Ⅰ-Ⅴ, S-parameter, and radio frequency （RF） large-signal characteristics are compared for a self-developed on-wafer A1GaN/GaN HEMT with ten gate fingers each being 0.4-μm long and 125-p-m wide （Such an A1GaN/GaN HEMT is denoted as A1GaN/GaN HEMT （10 × 125 μm））. The improved large signal model simulates the Ⅰ-Ⅴ characteristic much more accurately than the original one, and its transconductance and RF characteristics are also in excellent agreement with the measured data.
