This paper deals with the vitiation effects of test air on the scramjet performance in the ground combustion heated facilities. The primary goal is to evaluate the effects of H2O and CO2, the two major vitiated specie...This paper deals with the vitiation effects of test air on the scramjet performance in the ground combustion heated facilities. The primary goal is to evaluate the effects of H2O and CO2, the two major vitiated species generated by combustion heater, on hydrogen-fueled supersonic combustor performance with experimental and numerical approaches. The comparative experiments in the clean air and vitiated air are conducted by using the resistance heated direct-connected facility, with the typical Mach 4 flight conditions simulated. The H2O and CO2 species with accurately controlled contents are added to the high enthalpy clean air from resistance heater, to synthesize the vitiated air of a combustion-type heater. Typically, the contents of H2O species can be varied within the range of 3.5%-30% by mole, and 3.0%-10% for CO2 species. The total temperature, total pressure, Mach number and O2 mole fraction at the combustor entrance are well-matched between the clean air and vitiated air. The combustion experiments are completed at the fuel equivalence ratios of 0.53 and 0.42 respectively. Furthermore, three-dimensional （3D） reacting flow simulations of combustor flowpath are performed to provide insight into flow field structures and combustion chemistry details that cannot resolved by experimental instruments available. Finally, the experimental data, combined with computational results, are employed to analyze the effects of H2O and CO2 vitiated air on supersonic combustion characteristics and performance. It is concluded that H2O and CO2 contaminants can significantly inhibit the combustion induced pressure rise measured from combustor wall, and the pressure profile decreases with the increasing H2O and CO2 contents in nonlinear trend; simulation results agree well with experimental data and the overall vitiation effects are captured; direct extrapolation of the results from vitiated air to predict the performance of actual flight conditions could result in over-fueling the combustor, possible inlet un-start and inappropriate combustion mode transition. The detailed analysis and discussion are presented and the research conclusions are summarized.展开更多
Objective: To observe the effect and mechanism of Garlicin in treating coronary heart disease (CHD) with angina pectoris. Methods: Clinical study: 55 patients were selected and randomized into the Garlicin group and t...Objective: To observe the effect and mechanism of Garlicin in treating coronary heart disease (CHD) with angina pectoris. Methods: Clinical study: 55 patients were selected and randomized into the Garlicin group and the nitroglycerin group. To Garlicin group, 60 mg of Garlicin was given by adding in 5% glucose solution for intravenous dripping once per day, the therapeutic course展开更多
Polysocoharibe-peptide of Coriolus Versicolor (PSP) is a new anti-cancer immunomodulative drug. The present paper reports on the experimental research done with this drug. It was found that PSP had the ability to reco...Polysocoharibe-peptide of Coriolus Versicolor (PSP) is a new anti-cancer immunomodulative drug. The present paper reports on the experimental research done with this drug. It was found that PSP had the ability to recover hemolysin HC50, to increase the weight of the thymus, and increase the alexin of serum C3 and the IgG content of tumor bearing mice. FSP also significantly raised the pha-gocytic activity of macrophages in normal mice. PSP had a significant inhibitory effect on P38S and S180 cells. At the concentration of 1 mg/ml, PSP inhibited the proliferating activity of some human tumor call lines, such as SGC 7901, SPC, SLY and Mei. It had a direct toxic effect on SPC cells. PSP significantly inhibited the synthesis of nucleic acids of Ehrlich ascites carcinoma cells. In addition, PSP was antagonistic to the side effects of chemotherapy and radiotherapy.展开更多
The effect of the wave accessibility condition on the lower hybrid cm＇rent drive in the experimental advanced superconductor Tokamak （EAST） plasma with H-mode operation is studied. Based on a simplified model, a mo...The effect of the wave accessibility condition on the lower hybrid cm＇rent drive in the experimental advanced superconductor Tokamak （EAST） plasma with H-mode operation is studied. Based on a simplified model, a mode conversion layer of the lower hybrid wave between the fast wave branch and the slow wave branch is proved to exist in the plasma periphery for typical EAST H-mode parameters. Under the framework of the lower hybrid wave simulation code （LSC）, the wave ray trajectory and the associated current drive are calculated numerically. The results show that the wave accessibility condition plays an important role on the lower hybrid current drive in EAST plasma. For wave rays with parallel refractive index n｜｜= 2.1 or n｜｜ = 2.5 launched from the outside midplane, the wave rays may penetrate the core plasma due to the toroida] geometry effect, while numerous reflections of the wave ray trajectories in the plasma periphery occur. However, low current drive efficiency is obtained. Meanwhile, the wave accessibility condition is improved if a higher confined magnetic field is applied. The simulation results show that for plasma parameters under present EAST H-mode operation, a significant lower hybrid wave current drive could be obtained for the wave spectrum with peak value n｜｜ = 2.1 if a toroidal magnetic field BT =2.5 T is applied.展开更多
The effects of topography on baroclinic wave flows are studied experimentally in a thermally driven rotating annulus of fluid.Fourier analysis and complex principal component (CPC) analysis of the experimental data sh...The effects of topography on baroclinic wave flows are studied experimentally in a thermally driven rotating annulus of fluid.Fourier analysis and complex principal component (CPC) analysis of the experimental data show that, due to topographic forcing, the flow is bimodal rather than a single mode. Under suitable imposed experimental parameters, near thermal Rossby number ROT = 0.1 and Taylor number Ta = 2.2 × 107, the large-scale topography produces low-frequency oscillation in the flow and rather long-lived flow pattern resembling blocking in the atmospheric circulation. The 'blocking' phenomenon is caused by the resonance of travelling waves and the quasi-stationary waves forced by topography.The large-scale topography transforms wavenumber-homogeneous flows into wavenumber-dispersed flows, and the dispersed flows possess lower wavenumbers.展开更多
Recent experimental results of the Doppler effect formula verification are reported. The moving emitters are hydrogen atoms in the excited state. The results of the work corroborate the classical not the relativistic,...Recent experimental results of the Doppler effect formula verification are reported. The moving emitters are hydrogen atoms in the excited state. The results of the work corroborate the classical not the relativistic,formula for the Doppler effect.展开更多
1 Introduction Shallow water delta in the middle-newborn Stratum Widely developed with huge oil and gas in China(Hu Shengwu et al.,2013).The control factors on the deltadevelopment like Climate,sea level,tectonic subs...1 Introduction Shallow water delta in the middle-newborn Stratum Widely developed with huge oil and gas in China(Hu Shengwu et al.,2013).The control factors on the deltadevelopment like Climate,sea level,tectonic subsidence,sediment supply(flow,type),the geometric characteristics of the upstream river,the energy(wave,展开更多
Objective To investigate the role of endothelin(ET) in the proliferation and collagen synthesis of human scar-derived fibroblasts and the moduktion of its antagonists such as nitric oxide(NO), tetrandrine ( Tet). Meth...Objective To investigate the role of endothelin(ET) in the proliferation and collagen synthesis of human scar-derived fibroblasts and the moduktion of its antagonists such as nitric oxide(NO), tetrandrine ( Tet). Methods With the cultured fibroblasts from the scarring tissue, the cell pdiferation was determined by[3H]-TdR incorporation, while the collagen synthesis was evaluated by[3H]-proline incorporation. Results The ET-1 was significantly increasing the proliferation and collagen synthesis of human scar-derived fibroblasts. The values of [3H]-TdR absorption in the 2.5 ng/ml,25 ng/ml and 100 ng/ml of ET-1 groups were 1.8 times,4 times and 4.9 times more than in the control group, respectively(P【0. 01),while the values of the [3H]-proline incorporation were 1.1 times,3.1 times and 3.8 times respectively(P【0.01). The fibroblasts, treated with 50 μg/ml of S-nitroso-N-acetyl penicillamine(SNAP), were no detectable effect on the basal level of DNA synthesis,but produced decreasing effect on the展开更多
Objective To investigate the effect of adipose stromal vascular fraction cells(SVFs)on the survival rate of fat ransplantation.Methods 0.5mL autologous fat tissue was mixed with: ① DiI-labeled autologous SVFs (Group ...Objective To investigate the effect of adipose stromal vascular fraction cells(SVFs)on the survival rate of fat ransplantation.Methods 0.5mL autologous fat tissue was mixed with: ① DiI-labeled autologous SVFs (Group A);②展开更多
Objective To observe the preventive effect of continuous irrigation with sodium hyaluronate injection from peridural adhesionaminectomy.Methods Larninectomies were performed in L1,L4,L7 of 25 New Zealand rabbits respe...Objective To observe the preventive effect of continuous irrigation with sodium hyaluronate injection from peridural adhesionaminectomy.Methods Larninectomies were performed in L1,L4,L7 of 25 New Zealand rabbits respectively with 3展开更多
Soft and medium-hard rocks are subjected to high rheology under high stress,and they are prone to a relatively large-degree of deformation when perturbed by external impacting loads.The phenomenon where rock deformati...Soft and medium-hard rocks are subjected to high rheology under high stress,and they are prone to a relatively large-degree of deformation when perturbed by external impacting loads.The phenomenon where rock deformation is developed due to external impacting perturbation in the rheological state is defined as the rock rheological perturbation effect.This work presents a new experimental system for investigating the rock rheological perturbation effect with experiments on medium-hard red sandstone.Results from our analysis show that red sandstone changes under two mechanical mechanisms:deformation-hardening effects at low stress states,and damage-fracture effects at high stress states when impacted by certain external impacting loads.Red sandstone tested in our experiments has a strain threshold of about 90% of the ultimate strain under the perturbation effect;the red sandstone is sensitive to a perturbed load when its actual strain exceeds the threshold.The perturbed deformation process of the rock can be divided into three phases:decline,approximately constant speed and acceleration.The rock will be rapidly destroyed when the perturbed deformation accumulates to a certain degree.The perturbation effect of rock deformation under uniaxial compression is more obvious than that under axial compression.Based on our experiment,a constitutive relation of the rock rheological perturbation effect is developed.展开更多
Reinforcement Learning(RL)based control algorithms can learn the control strategies for nonlinear and uncertain environment during interacting with it.Guided by the rewards generated by environment,a RL agent can lear...Reinforcement Learning(RL)based control algorithms can learn the control strategies for nonlinear and uncertain environment during interacting with it.Guided by the rewards generated by environment,a RL agent can learn the control strategy directly in a model-free way instead of investigating the dynamic model of the environment.In the paper,we propose the sampled-data RL control strategy to reduce the computational demand.In the sampled-data control strategy,the whole control system is of a hybrid structure,in which the plant is of continuous structure while the controller(RL agent)adopts a discrete structure.Given that the continuous states of the plant will be the input of the agent,the state–action value function is approximated by the fully connected feed-forward neural networks(FCFFNN).Instead of learning the controller at every step during the interaction with the environment,the learning and acting stages are decoupled to learn the control strategy more effectively through experience replay.In the acting stage,the most effective experience obtained during the interaction with the environment will be stored and during the learning stage,the stored experience will be replayed to customized times,which helps enhance the experience replay process.The effectiveness of proposed approach will be verified by simulation examples.展开更多
Objective To reduce health-related threats of heat waves, interventions have been implemented in many parts of the world. However, there is a lack of higher-level evidence concerning the intervention efficacy. This st...Objective To reduce health-related threats of heat waves, interventions have been implemented in many parts of the world. However, there is a lack of higher-level evidence concerning the intervention efficacy. This study aimed to determine the efficacy of an intervention to reduce the number of heat-related illnesses. Methods A quasi-experimental design was employed by two cross-sectional surveys in the year 2024 and 2015, including 2,240 participants and 2,356 participants, respectively. Each survey was designed to include one control group and one intervention group, which conducted in Licheng, China. A representative sample was selected using a multistage sampling method. Data, collected from questionnaires about heat waves in 2014 and 2015, were analyzed using a difference-in-difference analysis and cost effectiveness analysis. Outcomes included changes in the prevalence of heat-related illnesses and cost-effectiveness variables. Results Relative to the control participants, the prevalence of heat-related illness in the intervention participants decreased to a greater extent in rural areas than in urban areas （OR=0.495 vs. OR=2.282）. Moreover, the cost-effectiveness ratio in the intervention group was tess than that in the control group （usS25.06 vs. us$25.69 per participant）. Furthermore, to avoid one additional patient, the incremental cost-effectiveness ratio showed that an additional USS14.47 would be needed for the intervention compared to when no intervention was applied. Conclusion The intervention program may be considered a worthwhile investment for rural areas that are more likely to experience heat waves. Meanwhile, corresponding improving measures should be presented towards urban areas. Future research should examine whether the intervention strategies could be spread out in other domestic or international regions where heat waves are usually experienced.展开更多
Fiber reinforced anti-hard-target warhead is a new-type sample munition, which is only designed based on theoretical analysis and numerical simulation in laboratory. This warhead consists of carbon composite casings a...Fiber reinforced anti-hard-target warhead is a new-type sample munition, which is only designed based on theoretical analysis and numerical simulation in laboratory. This warhead consists of carbon composite casings and high explosive, which can greatly reduce the damage to objects outside the damage range. In order to evaluate its blasting damage effect on concrete target, the three types of charges were researched by means of experiment, which are bare charge, charge with carbon composite material shell and charge with steel shell. Experimental results show that the peak overpressure of charge with carbon fiber composite shell is higher than that of charge with steel shell, but is lower than that of bare charge in the case of the same TNT equivalence. No fragments and fragment effect exist for distant target under the condition of charge with carbon fiber composite shell. However, the experimental result of the charge with steel shell is completely contrary. According to the blast effect in the concrete target, the charge with carbon composite material shell is optimal in matched impedance and detonation propagation.Also, the effective energy produced by the detonation of explosive with carbon composite material shell is the largest.展开更多
The complex geographical environment in China makes its gravity signals miscellaneous.This work gives a comprehensive representation and explanation in secular trend of gravity change in different regions,the key feat...The complex geographical environment in China makes its gravity signals miscellaneous.This work gives a comprehensive representation and explanation in secular trend of gravity change in different regions,the key features of which include positive trend in inner Tibet Plateau and South China and negative trend in North China plain and high mountain Asia（HMA）.We also present the patterns of amplitudes and phases of annual and semiannual change.The mechanism underlying the semiannual period is explicitly discussed.The displacement in three directions expressed in terms of geo-potential spherical coefficients and load Love numbers are given.A case study applied with these equations is presented.The results show that Global Positioning System（GPS） observations can be used to compare with Gravity Recovery and Climate Experiment（GRACE） derived displacement and the vertical direction has a signal-noise-ratio of about one order of magnitude larger than the horizontal directions.展开更多
An experimental study is made to investigate the film cooling performance of imperfect holes due to in-hole blockage over a flat plate. A specifically pyramid-shaped element is used to simulate the in-hole blockage. S...An experimental study is made to investigate the film cooling performance of imperfect holes due to in-hole blockage over a flat plate. A specifically pyramid-shaped element is used to simulate the in-hole blockage. Six in-hole blockage orientations（such as leading-inlet, leading-middle,leading-exit, trailing-inlet, trailing-middle and trailing-exit） and four blocking ratios（ranging from 0.1 to 0.4） are taken into considerations. Based on the experimental results, the influences of in-hole blockage on the film cooling effectiveness and discharge coefficient under typical blowing ratios are analyzed. It is confirmed that the in-hole blockage results in a reduction of discharge coefficient related to the perfect film cooling holes, especially for the leading-exit and trailing-inlet orientations with a big blocking ratio. However, in the view of film cooling effectiveness, the in-hole blockage shows complicated affecting roles. In general, except for the leading-exit orientation, the in-hole blockages produce detrimental influence on the film cooling effectiveness.展开更多
This paper presents a theoretical calculation of the effects of relativistic broadening and frequency down-shift on the electron cyclotron emission measurements for a wide range of plasma parameters in the Experimenta...This paper presents a theoretical calculation of the effects of relativistic broadening and frequency down-shift on the electron cyclotron emission measurements for a wide range of plasma parameters in the Experimental Advanced Superconducting Tokamak （EAST）. The calculation is based on the radiation transfer equation, with the reabsorption and reemission processes taken into account. The broadening effect contributes to the radial resolution of the measurement, and the calculation results indicate that it is -2 cm in the case of the central electron temperature 10 keV. A pseudo radial displacement of the obtained electron temperature profile occurs if the relativistic frequency down-shift effect is not taken into account in the determination of the emission layer position. The shift could be a few centimeters as the electron temperature increases, and this effect should be taken into account.展开更多
Objective: To discuss the application experience of abdominal color Doppler ultrasound based on the diagnosis results of gynecological acute abdomen. Methods: Sixty-eight patients with gynecological acute abdomen were...Objective: To discuss the application experience of abdominal color Doppler ultrasound based on the diagnosis results of gynecological acute abdomen. Methods: Sixty-eight patients with gynecological acute abdomen were sampled and treated in our hospital from December 2020 to December 2021. The results of surgical and pathological diagnosis were taken as the gold standard. All patients were examined by abdominal color Doppler ultrasound, and the diagnostic accuracy of different types of acute abdomen was compared retrospectively. Results: Summarizing the data in Table 1, in the surgical and pathological diagnosis, the number of confirmed samples of ovarian cyst rupture, ovarian corpus luteum rupture, incomplete abortion of acute pelvic inflammatory disease and ectopic pregnancy were 5, 2, 14, 11 and 36 cases in turn, which were the gold standard. The diagnostic accuracy of abdominal ultrasound for the above types of gynecological acute abdomen was 80%(4/5), 100%(2/2), and Conclusion: Abdominal color Doppler ultrasound has high diagnostic accuracy, fast examination speed, few misdiagnosis and missed diagnosis samples, and many application advantages. It can not only repeat the examination operation, but also dynamically monitor the specific trend of the disease progress, and guide doctors to formulate targeted treatment plans.展开更多
文摘This paper deals with the vitiation effects of test air on the scramjet performance in the ground combustion heated facilities. The primary goal is to evaluate the effects of H2O and CO2, the two major vitiated species generated by combustion heater, on hydrogen-fueled supersonic combustor performance with experimental and numerical approaches. The comparative experiments in the clean air and vitiated air are conducted by using the resistance heated direct-connected facility, with the typical Mach 4 flight conditions simulated. The H2O and CO2 species with accurately controlled contents are added to the high enthalpy clean air from resistance heater, to synthesize the vitiated air of a combustion-type heater. Typically, the contents of H2O species can be varied within the range of 3.5%-30% by mole, and 3.0%-10% for CO2 species. The total temperature, total pressure, Mach number and O2 mole fraction at the combustor entrance are well-matched between the clean air and vitiated air. The combustion experiments are completed at the fuel equivalence ratios of 0.53 and 0.42 respectively. Furthermore, three-dimensional （3D） reacting flow simulations of combustor flowpath are performed to provide insight into flow field structures and combustion chemistry details that cannot resolved by experimental instruments available. Finally, the experimental data, combined with computational results, are employed to analyze the effects of H2O and CO2 vitiated air on supersonic combustion characteristics and performance. It is concluded that H2O and CO2 contaminants can significantly inhibit the combustion induced pressure rise measured from combustor wall, and the pressure profile decreases with the increasing H2O and CO2 contents in nonlinear trend; simulation results agree well with experimental data and the overall vitiation effects are captured; direct extrapolation of the results from vitiated air to predict the performance of actual flight conditions could result in over-fueling the combustor, possible inlet un-start and inappropriate combustion mode transition. The detailed analysis and discussion are presented and the research conclusions are summarized.
文摘Objective: To observe the effect and mechanism of Garlicin in treating coronary heart disease (CHD) with angina pectoris. Methods: Clinical study: 55 patients were selected and randomized into the Garlicin group and the nitroglycerin group. To Garlicin group, 60 mg of Garlicin was given by adding in 5% glucose solution for intravenous dripping once per day, the therapeutic course
文摘Polysocoharibe-peptide of Coriolus Versicolor (PSP) is a new anti-cancer immunomodulative drug. The present paper reports on the experimental research done with this drug. It was found that PSP had the ability to recover hemolysin HC50, to increase the weight of the thymus, and increase the alexin of serum C3 and the IgG content of tumor bearing mice. FSP also significantly raised the pha-gocytic activity of macrophages in normal mice. PSP had a significant inhibitory effect on P38S and S180 cells. At the concentration of 1 mg/ml, PSP inhibited the proliferating activity of some human tumor call lines, such as SGC 7901, SPC, SLY and Mei. It had a direct toxic effect on SPC cells. PSP significantly inhibited the synthesis of nucleic acids of Ehrlich ascites carcinoma cells. In addition, PSP was antagonistic to the side effects of chemotherapy and radiotherapy.
基金Supported by the National Natural Science Foundation of China under Grant No 11347002the National Magnetic Confinement Fusion Science Program of China under Grant No 2013GB111000+2 种基金the Outstanding Youth Fund of Hunan Province Education Department of China under Grant No 12B107the JSPS-NRF-NSFC A3 Foresight Program in the field of Plasma Physics under Grant No 11261140328the National Research Foundation 2012K2A2A6000443
文摘The effect of the wave accessibility condition on the lower hybrid cm＇rent drive in the experimental advanced superconductor Tokamak （EAST） plasma with H-mode operation is studied. Based on a simplified model, a mode conversion layer of the lower hybrid wave between the fast wave branch and the slow wave branch is proved to exist in the plasma periphery for typical EAST H-mode parameters. Under the framework of the lower hybrid wave simulation code （LSC）, the wave ray trajectory and the associated current drive are calculated numerically. The results show that the wave accessibility condition plays an important role on the lower hybrid current drive in EAST plasma. For wave rays with parallel refractive index n｜｜= 2.1 or n｜｜ = 2.5 launched from the outside midplane, the wave rays may penetrate the core plasma due to the toroida] geometry effect, while numerous reflections of the wave ray trajectories in the plasma periphery occur. However, low current drive efficiency is obtained. Meanwhile, the wave accessibility condition is improved if a higher confined magnetic field is applied. The simulation results show that for plasma parameters under present EAST H-mode operation, a significant lower hybrid wave current drive could be obtained for the wave spectrum with peak value n｜｜ = 2.1 if a toroidal magnetic field BT =2.5 T is applied.
基金This research was supported by the U.S. National Science Foundation Grants ATM-8709410 and ATM-8714674.
文摘The effects of topography on baroclinic wave flows are studied experimentally in a thermally driven rotating annulus of fluid.Fourier analysis and complex principal component (CPC) analysis of the experimental data show that, due to topographic forcing, the flow is bimodal rather than a single mode. Under suitable imposed experimental parameters, near thermal Rossby number ROT = 0.1 and Taylor number Ta = 2.2 × 107, the large-scale topography produces low-frequency oscillation in the flow and rather long-lived flow pattern resembling blocking in the atmospheric circulation. The 'blocking' phenomenon is caused by the resonance of travelling waves and the quasi-stationary waves forced by topography.The large-scale topography transforms wavenumber-homogeneous flows into wavenumber-dispersed flows, and the dispersed flows possess lower wavenumbers.
文摘Recent experimental results of the Doppler effect formula verification are reported. The moving emitters are hydrogen atoms in the excited state. The results of the work corroborate the classical not the relativistic,formula for the Doppler effect.
文摘1 Introduction Shallow water delta in the middle-newborn Stratum Widely developed with huge oil and gas in China(Hu Shengwu et al.,2013).The control factors on the deltadevelopment like Climate,sea level,tectonic subsidence,sediment supply(flow,type),the geometric characteristics of the upstream river,the energy(wave,
文摘Objective To investigate the role of endothelin(ET) in the proliferation and collagen synthesis of human scar-derived fibroblasts and the moduktion of its antagonists such as nitric oxide(NO), tetrandrine ( Tet). Methods With the cultured fibroblasts from the scarring tissue, the cell pdiferation was determined by[3H]-TdR incorporation, while the collagen synthesis was evaluated by[3H]-proline incorporation. Results The ET-1 was significantly increasing the proliferation and collagen synthesis of human scar-derived fibroblasts. The values of [3H]-TdR absorption in the 2.5 ng/ml,25 ng/ml and 100 ng/ml of ET-1 groups were 1.8 times,4 times and 4.9 times more than in the control group, respectively(P【0. 01),while the values of the [3H]-proline incorporation were 1.1 times,3.1 times and 3.8 times respectively(P【0.01). The fibroblasts, treated with 50 μg/ml of S-nitroso-N-acetyl penicillamine(SNAP), were no detectable effect on the basal level of DNA synthesis,but produced decreasing effect on the
文摘Objective To investigate the effect of adipose stromal vascular fraction cells(SVFs)on the survival rate of fat ransplantation.Methods 0.5mL autologous fat tissue was mixed with: ① DiI-labeled autologous SVFs (Group A);②
文摘Objective To observe the preventive effect of continuous irrigation with sodium hyaluronate injection from peridural adhesionaminectomy.Methods Larninectomies were performed in L1,L4,L7 of 25 New Zealand rabbits respectively with 3
基金Projects(51474218,51304127,50474029)supported by the National Natural Science Foundation of ChinaProject(2016M590646)supported by China Postdoctoral Science FoundationProject(2016121)supported by Qingdao Postdoctoral Applied Research Foundation,China
文摘Soft and medium-hard rocks are subjected to high rheology under high stress,and they are prone to a relatively large-degree of deformation when perturbed by external impacting loads.The phenomenon where rock deformation is developed due to external impacting perturbation in the rheological state is defined as the rock rheological perturbation effect.This work presents a new experimental system for investigating the rock rheological perturbation effect with experiments on medium-hard red sandstone.Results from our analysis show that red sandstone changes under two mechanical mechanisms:deformation-hardening effects at low stress states,and damage-fracture effects at high stress states when impacted by certain external impacting loads.Red sandstone tested in our experiments has a strain threshold of about 90% of the ultimate strain under the perturbation effect;the red sandstone is sensitive to a perturbed load when its actual strain exceeds the threshold.The perturbed deformation process of the rock can be divided into three phases:decline,approximately constant speed and acceleration.The rock will be rapidly destroyed when the perturbed deformation accumulates to a certain degree.The perturbation effect of rock deformation under uniaxial compression is more obvious than that under axial compression.Based on our experiment,a constitutive relation of the rock rheological perturbation effect is developed.
基金supported by Imperial College London,UK,King’s College London,UK and Engineering and Physical Sciences Research Council(EPSRC),UK.
文摘Reinforcement Learning(RL)based control algorithms can learn the control strategies for nonlinear and uncertain environment during interacting with it.Guided by the rewards generated by environment,a RL agent can learn the control strategy directly in a model-free way instead of investigating the dynamic model of the environment.In the paper,we propose the sampled-data RL control strategy to reduce the computational demand.In the sampled-data control strategy,the whole control system is of a hybrid structure,in which the plant is of continuous structure while the controller(RL agent)adopts a discrete structure.Given that the continuous states of the plant will be the input of the agent,the state–action value function is approximated by the fully connected feed-forward neural networks(FCFFNN).Instead of learning the controller at every step during the interaction with the environment,the learning and acting stages are decoupled to learn the control strategy more effectively through experience replay.In the acting stage,the most effective experience obtained during the interaction with the environment will be stored and during the learning stage,the stored experience will be replayed to customized times,which helps enhance the experience replay process.The effectiveness of proposed approach will be verified by simulation examples.
基金supported by National Basic Research Program of China(973 Program)(Grant No.2012CB955504)
文摘Objective To reduce health-related threats of heat waves, interventions have been implemented in many parts of the world. However, there is a lack of higher-level evidence concerning the intervention efficacy. This study aimed to determine the efficacy of an intervention to reduce the number of heat-related illnesses. Methods A quasi-experimental design was employed by two cross-sectional surveys in the year 2024 and 2015, including 2,240 participants and 2,356 participants, respectively. Each survey was designed to include one control group and one intervention group, which conducted in Licheng, China. A representative sample was selected using a multistage sampling method. Data, collected from questionnaires about heat waves in 2014 and 2015, were analyzed using a difference-in-difference analysis and cost effectiveness analysis. Outcomes included changes in the prevalence of heat-related illnesses and cost-effectiveness variables. Results Relative to the control participants, the prevalence of heat-related illness in the intervention participants decreased to a greater extent in rural areas than in urban areas （OR=0.495 vs. OR=2.282）. Moreover, the cost-effectiveness ratio in the intervention group was tess than that in the control group （usS25.06 vs. us$25.69 per participant）. Furthermore, to avoid one additional patient, the incremental cost-effectiveness ratio showed that an additional USS14.47 would be needed for the intervention compared to when no intervention was applied. Conclusion The intervention program may be considered a worthwhile investment for rural areas that are more likely to experience heat waves. Meanwhile, corresponding improving measures should be presented towards urban areas. Future research should examine whether the intervention strategies could be spread out in other domestic or international regions where heat waves are usually experienced.
基金partially sponsored by the Chinese-NSF Foundation(11672278)Chinese-NDTF(B1520132012)
文摘Fiber reinforced anti-hard-target warhead is a new-type sample munition, which is only designed based on theoretical analysis and numerical simulation in laboratory. This warhead consists of carbon composite casings and high explosive, which can greatly reduce the damage to objects outside the damage range. In order to evaluate its blasting damage effect on concrete target, the three types of charges were researched by means of experiment, which are bare charge, charge with carbon composite material shell and charge with steel shell. Experimental results show that the peak overpressure of charge with carbon fiber composite shell is higher than that of charge with steel shell, but is lower than that of bare charge in the case of the same TNT equivalence. No fragments and fragment effect exist for distant target under the condition of charge with carbon fiber composite shell. However, the experimental result of the charge with steel shell is completely contrary. According to the blast effect in the concrete target, the charge with carbon composite material shell is optimal in matched impedance and detonation propagation.Also, the effective energy produced by the detonation of explosive with carbon composite material shell is the largest.
基金supported financially by the National Natural Science Foundation of China(41174063,41331066 and41474059)the CAS/CAFEA International Partnership Program for Creative Research Teams(KZZD-EW-TZ-19)the SKLGED Foundation(2014-1-1-E)
文摘The complex geographical environment in China makes its gravity signals miscellaneous.This work gives a comprehensive representation and explanation in secular trend of gravity change in different regions,the key features of which include positive trend in inner Tibet Plateau and South China and negative trend in North China plain and high mountain Asia（HMA）.We also present the patterns of amplitudes and phases of annual and semiannual change.The mechanism underlying the semiannual period is explicitly discussed.The displacement in three directions expressed in terms of geo-potential spherical coefficients and load Love numbers are given.A case study applied with these equations is presented.The results show that Global Positioning System（GPS） observations can be used to compare with Gravity Recovery and Climate Experiment（GRACE） derived displacement and the vertical direction has a signal-noise-ratio of about one order of magnitude larger than the horizontal directions.
基金the financial support for this project from the National Natural Science Foundation of China (Nos.51276090 and U1508212)
文摘An experimental study is made to investigate the film cooling performance of imperfect holes due to in-hole blockage over a flat plate. A specifically pyramid-shaped element is used to simulate the in-hole blockage. Six in-hole blockage orientations（such as leading-inlet, leading-middle,leading-exit, trailing-inlet, trailing-middle and trailing-exit） and four blocking ratios（ranging from 0.1 to 0.4） are taken into considerations. Based on the experimental results, the influences of in-hole blockage on the film cooling effectiveness and discharge coefficient under typical blowing ratios are analyzed. It is confirmed that the in-hole blockage results in a reduction of discharge coefficient related to the perfect film cooling holes, especially for the leading-exit and trailing-inlet orientations with a big blocking ratio. However, in the view of film cooling effectiveness, the in-hole blockage shows complicated affecting roles. In general, except for the leading-exit orientation, the in-hole blockages produce detrimental influence on the film cooling effectiveness.
基金supported by the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. Y05FCQ0125)the National Magnetic Confinement Fusion Science Program of China (Grant No. 2011GB107001)
文摘This paper presents a theoretical calculation of the effects of relativistic broadening and frequency down-shift on the electron cyclotron emission measurements for a wide range of plasma parameters in the Experimental Advanced Superconducting Tokamak （EAST）. The calculation is based on the radiation transfer equation, with the reabsorption and reemission processes taken into account. The broadening effect contributes to the radial resolution of the measurement, and the calculation results indicate that it is -2 cm in the case of the central electron temperature 10 keV. A pseudo radial displacement of the obtained electron temperature profile occurs if the relativistic frequency down-shift effect is not taken into account in the determination of the emission layer position. The shift could be a few centimeters as the electron temperature increases, and this effect should be taken into account.
文摘Objective: To discuss the application experience of abdominal color Doppler ultrasound based on the diagnosis results of gynecological acute abdomen. Methods: Sixty-eight patients with gynecological acute abdomen were sampled and treated in our hospital from December 2020 to December 2021. The results of surgical and pathological diagnosis were taken as the gold standard. All patients were examined by abdominal color Doppler ultrasound, and the diagnostic accuracy of different types of acute abdomen was compared retrospectively. Results: Summarizing the data in Table 1, in the surgical and pathological diagnosis, the number of confirmed samples of ovarian cyst rupture, ovarian corpus luteum rupture, incomplete abortion of acute pelvic inflammatory disease and ectopic pregnancy were 5, 2, 14, 11 and 36 cases in turn, which were the gold standard. The diagnostic accuracy of abdominal ultrasound for the above types of gynecological acute abdomen was 80%(4/5), 100%(2/2), and Conclusion: Abdominal color Doppler ultrasound has high diagnostic accuracy, fast examination speed, few misdiagnosis and missed diagnosis samples, and many application advantages. It can not only repeat the examination operation, but also dynamically monitor the specific trend of the disease progress, and guide doctors to formulate targeted treatment plans.
