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TIPS联合肠系膜下静脉弹簧圈栓塞治疗肝硬化患者复发性痔出血:1例报道
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作者 王海洲 陈立平 王晓兵 《胃肠病学和肝病学杂志》 2026年第2期261-263,共3页
痔疮是目前最常见的疾病之一,常伴出血、脱垂、疼痛和瘙痒。目前,痔疮治疗以非手术或保守治疗为主,例如套扎、硬化治疗等。然而,肝硬化合并内痔出血尚无标准的治疗方案。1例68岁的肝硬化门静脉高压症女性患者在接受两次内镜硬化治疗后,... 痔疮是目前最常见的疾病之一,常伴出血、脱垂、疼痛和瘙痒。目前,痔疮治疗以非手术或保守治疗为主,例如套扎、硬化治疗等。然而,肝硬化合并内痔出血尚无标准的治疗方案。1例68岁的肝硬化门静脉高压症女性患者在接受两次内镜硬化治疗后,仍因“反复便血4个月”入院。通过腹盆的增强计算机断层扫描(computed tomography, CT)和结肠镜检查,我们发现这位肝硬化患者的内痔静脉曲张与门脉高压之间存在相关性。因此,我们考虑选择经颈静脉肝内门体分流术(transjugular intrahepatic portosystemic shunt, TIPS)作为该患者的治疗手段。术中造影发现肠系膜上静脉内为完全的远肝血流。术中完成TIPS+门静脉血栓抽吸+弹簧圈肠系膜下静脉栓塞,门静脉压力从27 mmHg降至11 mmHg。在后续3年的随访期间,患者未出现任何消化道出血,血红蛋白水平也显著回升。本病例报告表明,如果内镜治疗失败,并且排除了其他出血原因,TIPS可以作为肝硬化门脉高压患者内痔出血的替代治疗措施。 展开更多
关键词 内痔出血 tips 肝硬化
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Negative Coulomb drag between graphene quantum Hall edges
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作者 SONG Junwei GAN Qikang +4 位作者 ZHU Wang WATANABE Kenji TANIGUCHI Takashi YU Geliang WANG Lei 《物理学进展》 北大核心 2026年第1期1-12,共12页
Coulomb drag refers to the phenomenon in which a current driven through one conducting layer induces a voltage nearby,electrically isolated layer sorely through interlayer Coulomb interactions between charge carriers.... Coulomb drag refers to the phenomenon in which a current driven through one conducting layer induces a voltage nearby,electrically isolated layer sorely through interlayer Coulomb interactions between charge carriers.It has been extensively studied in various systems,including parallel nanowires,double quantum wells,and double-layer graphene.Here,we report the observation of Coulomb drag in a novel system consisting of two graphene layers separated laterally by a 30 nm gap within the material plane,exhibiting behavior distinct from that in vertical graphene heterostructures.Our experiments reveal pronounced negative drag resistances under an out-of-plane magnetic field at the quantum Hall edges,reaching a maximum when the carrier densities in both graphene layers are tuned to the charge neutrality point via gate voltages.Our work establish two separate and spatially closed quantum Hall edge modes as a new platform to explore electronic interaction physics between one dimensional systems. 展开更多
关键词 negative Coulomb drag quantum Hall edges van der Waals heterostructures
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Hypersonic Flow over V-Shaped Leading Edges:A Review of Shock Interactions and Aerodynamic Loads
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作者 Xinyue Dong Wei Zhao +4 位作者 Jingying Wang Shiyue Zhang Yue Zhou Xinglian Yang Chunhian Lee 《Fluid Dynamics & Materials Processing》 2026年第1期26-44,共19页
For hypersonic air-breathing vehicles,the V-shaped leading edges(VSLEs)of supersonic combustion ramjet(scramjet)inlets experience complex shock interactions and intense aerodynamic loads.This paper provides a comprehe... For hypersonic air-breathing vehicles,the V-shaped leading edges(VSLEs)of supersonic combustion ramjet(scramjet)inlets experience complex shock interactions and intense aerodynamic loads.This paper provides a comprehensive review of flow characteristics at the crotch of VSLEs,with particular focus on the transition of shock interaction types and the variation of wall heat flux under different freestream Mach numbers and geometric configurations.The mechanisms governing shock transition,unsteady oscillations,hysteresis,and three-dimensional effects in VSLE flows are first examined.Subsequently,thermal protection strategies aimed at mitigating extreme heating loads are reviewed,emphasizing their relevance to practical engineering applications.Special attention is given to recent studies addressing thermochemical nonequilibrium effects on VSLE shock interactions,and the limitations of current research are critically assessed.Finally,perspectives for future investigations into hypersonic VSLE shock interactions are outlined,highlighting opportunities for advancing design and thermal management strategies. 展开更多
关键词 V-shaped leading edges shock interaction SCRAMJET thermochemical nonequilibrium aerodynamic heating
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Edge-based dynamic event-triggered inverse optimal formation control of multiple QUAVs with attitude constraints
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作者 Yonghua PENG Hui MA +1 位作者 Hongru REN Hongyi LI 《Science China(Technological Sciences)》 2026年第3期201-213,共13页
This paper investigates the edge-based dynamic event-triggered inverse optimal formation control problem for multiple quadrotor unmanned aerial vehicles(QUAVs) with attitude constraints. To improve communication effic... This paper investigates the edge-based dynamic event-triggered inverse optimal formation control problem for multiple quadrotor unmanned aerial vehicles(QUAVs) with attitude constraints. To improve communication efficiency, an edge-based dynamic event-triggered mechanism is developed for the communication channels between neighboring QUAVs. However, this edge-based dynamic event-triggered communication(DETC) may cause discontinuities in the reference signals. To solve this problem, a distributed estimator is designed for each QUAV to obtain the leader's output signals. Considering the safety of QUAV formation flying, this paper designs a function transformation method that constrains the attitudes of the QUAVs to a strictly safe region. Furthermore, an inverse optimal control strategy is proposed based on the backstepping methodology. This scheme not only minimizes the cost function but also avoids the necessity of solving the Hamilton-Jacobi-Bellman equation. Finally, the stability of the QUAV systems is proven using Lyapunov theory, and the effectiveness of the proposed control method is verified through simulation. 展开更多
关键词 edge event-triggered mechanism formation control inverse optimal control quadrotor unmanned aerial vehicles(QUAVs)
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基于教、学、评一体化的高中英语读后续写TIPS教学模式的建构与实践
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作者 徐长群 《教学月刊(中学版)(外语教学)》 2026年第1期72-78,共7页
读后续写是一种将阅读与写作紧密结合的考查形式,要求考生对所读材料进行续写,将其发展成一篇与给定材料有所衔接、情节架构自然,而且结构完整的短文。基于教、学、评一体化的高中英语读后续写TIPS教学模式有助于解决当前高中英语读后... 读后续写是一种将阅读与写作紧密结合的考查形式,要求考生对所读材料进行续写,将其发展成一篇与给定材料有所衔接、情节架构自然,而且结构完整的短文。基于教、学、评一体化的高中英语读后续写TIPS教学模式有助于解决当前高中英语读后续写教学存在的应试倾向严重、侧重指导学生堆砌华丽辞藻和套用写作套路、教师的评分较为主观等问题,其教学从量规驱动、情节共创、语言打磨、意义反思四个维度推进续作与阅读语篇的有机协同,有助于学生准确把握写作主题,创作出生动的情节,形成正确的价值观和良好的品格。 展开更多
关键词 读后续写 教、学、评一体化 tips教学模式 高中英语
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肝硬化门静脉高压并发EVB患者TIPS术后死亡风险预测模型的构建与验证
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作者 杨小东 马志刚 +2 位作者 王旭 刘丽丽 冯鹏丽 《中国现代普通外科进展》 2025年第11期853-858,共6页
目的:探讨肝硬化门静脉高压并发食管胃底静脉曲张破裂出血(EVB)患者经颈静脉肝内门体分流术(TIPS)治疗后死亡的危险因素,并建立预测模型,为临床治疗提供参考依据。方法:回顾性分析2022年3月—2024年3月在保定市第二中心医院接受TIPS治疗... 目的:探讨肝硬化门静脉高压并发食管胃底静脉曲张破裂出血(EVB)患者经颈静脉肝内门体分流术(TIPS)治疗后死亡的危险因素,并建立预测模型,为临床治疗提供参考依据。方法:回顾性分析2022年3月—2024年3月在保定市第二中心医院接受TIPS治疗的80例肝硬化门静脉高压并发EVB患者的临床资料。根据28 d随访结果将患者分为存活组(n=65)和死亡组(n=15)。收集患者的一般资料、实验室检查、影像学特征、并发症情况及手术相关指标等数据。采用单因素分析筛选可能的危险因素,通过多元Logistic回归分析确定独立危险因素并构建预测模型。应用Hosmer-Lemeshow检验评估模型校准度,采用ROC曲线评估模型区分度。结果:单因素分析显示,两组在年龄、治疗时机、Child-pugh评分、MELD评分、血红蛋白、血小板计数、总胆红素、白蛋白、凝血酶原时间、出血量、门静脉血栓、肝性脑病、肝肾综合征等方面差异有统计学意义(P<0.05)。多元Logistic回归分析确定Child-pugh评分(OR=2.653,95%CI:1.672~4.207)、MELD评分(OR=1.924,95%CI:1.298~2.851)、出血量(OR=1.754,95%CI:1.235~2.489)、门静脉血栓(OR=3.247,95%CI:1.569~6.723)、肝性脑病(OR=2.834,95%CI:1.421~5.657)为肝硬化门静脉高压并发EVB患者TIPS治疗后死亡的独立危险因素(P<0.05)。预测模型的HosmerLemeshow检验提示模型具有良好的校准度(χ^(2)=6.234,P=0.621)。ROC曲线分析显示,模型的AUC为0.873(95%CI:0.773~0.939),敏感度为83.3%,特异度为87.7%。结论:Child-pugh评分、MELD评分、出血量、门静脉血栓及肝性脑病是肝硬化门静脉高压并发EVB患者TIPS治疗后死亡的独立危险因素。本研究建立的预测模型具有良好的预测效能,可为临床评估患者预后及制定个体化治疗方案提供参考。 展开更多
关键词 肝硬化 门静脉高压 食管胃底静脉曲张破裂出血 介入治疗 危险因素 预测模型
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哮喘患者血清lncRNA HOTTIP和RMRP水平表达及与气道重塑的相关性分析
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作者 郁芳芳 谢伟国 许群 《现代检验医学杂志》 2026年第1期70-74,85,共6页
目的探究哮喘患者血清长链非编码RNA(lncRNA)HOXA末端转录本反义RNA(HOTTIP)和线粒体RNA处理核糖核酸内切酶RNA组份(RMRP)表达变化及其与气道重塑的相关性。方法选取2022年1月~2024年6月江苏省江阴市人民医院呼吸与危重症医学科收治的... 目的探究哮喘患者血清长链非编码RNA(lncRNA)HOXA末端转录本反义RNA(HOTTIP)和线粒体RNA处理核糖核酸内切酶RNA组份(RMRP)表达变化及其与气道重塑的相关性。方法选取2022年1月~2024年6月江苏省江阴市人民医院呼吸与危重症医学科收治的急性发作期哮喘患者72例为急性发作期组,同期门诊随访哮喘缓解期患者70例为缓解期组,健康体检者142例为健康对照组。采用实时荧光定量聚合酶链反应(qRT-PCR)检测血清lncRNA HOTTIP和RMRP水平。采用多排螺旋CT测量患者肺内气道的内径(L)、外径(D),计算气道壁厚度与气道外径比值(T/D)和管壁面积占支气道总横截面积百分比(WA%)。采用肺功能检测仪检测第一秒用力呼气量(FEV1)、最高呼吸气流(PEF)水平。Spearman相关性分析哮喘患者血清lncRNA HOTTIP和RMRP水平与哮喘控制测试(ACT)评分的关系。Pearson相关性分析哮喘患者血清lncRNA HOTTIP和RMRP水平以及与肿瘤坏死因子-α(TNF-α)、γ干扰素(IFN-γ)、白细胞介素-18(IL-18)水平、气道重塑以及肺功能指标的关系。结果与健康对照组相比,急性发作期组和缓解期组IFN-γ水平显著降低(t=14.161,8.886),TNF-α、IL-18、lncRNA HOTTIP(1.32±0.15、1.15±0.15 vs 1.01±0.14)和RMRP(1.27±0.14、1.16±0.14 vs 1.02±0.13)水平显著升高(t=9.345~28.361);与缓解期组相比,急性发作期组ACT评分、IFN-γ水平显著降低(t=13.344,4.475),TNF-α、IL-18、lncRNA HOTTIP和RMRP水平显著升高(t=6.861~15.675),差异具有统计学意义(均P<0.05)。与健康对照组相比,急性发作期组和缓解期组FEV1、PEF水平显著降低(t=13.346~55.694),T/D、WA%水平显著升高(t=19.145~33.035);与缓解期组相比,急性发作期组FEV1、PEF水平显著降低(t=21.802、21.446),T/D、WA%水平显著升高(t=9.994、10.082),差异具有统计学意义(均P<0.05)。Spearman相关性分析显示哮喘患者血清lncRNA HOTTIP和RMRP水平与ACT评分呈负相关(r=-0.614、-0.399,均P<0.001)。Pearson相关性分析显示,哮喘患者血清lncRNA HOTTIP和RMRP水平呈正相关(r=0.625,P<0.05)。哮喘患者血清lncRNA HOTTIP和RMRP水平与TNF-α(r=0.658、0.632)、IL-18(r=0.584、0.586)、T/D(r=0.604、0.631)、WA%(r=0.597、0.588)水平呈正相关,与IFN-γ(r=-0.587、-0.517)、FEV1(r=-0.568、-0.577)、PEF(r=-0.634、-0.627)水平呈负相关(均P<0.05)。结论哮喘患者血清lncRNA HOTTIP和RMRP水平均呈高表达,与气道重塑和肺功能指标变化有关。 展开更多
关键词 哮喘 长链非编码核糖核酸HOXA末端转录本反义RNA 线粒体RNA处理核糖核酸内切酶RNA组份 气道重塑
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核心素养视角下运用数字资源构建TIPS集体备课模式的策略探究
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作者 张栋 梁治华 《求知导刊》 2025年第20期26-28,共3页
以发展学生核心素养为基本目标,着重探讨了TIPS集体备课模式的概念、应用价值和构建策略。教育部门和学校应通力合作,积极整合数字资源,重构备课流程,创新备课方式,推进动态评价,以确保数字化集体备课取得积极成果。
关键词 核心素养 tips集体备课模式 数字资源 教学能力
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肝脏“搭桥术”TIPS的前世今生
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作者 张信哲 贺娜 《肝博士》 2025年第3期31-32,共2页
疏浚河道、搭桥通航,自古以来都是疏通水运,繁荣经济的重要举措。门静脉系是人体最大的、收集腹腔内不成对脏器(如脾、胰、肠等)血液回流的主干道,当它的血液回流受阻,如常见的肝硬化导致门脉系血液回流受阻,便会发生类似河道壅塞的情... 疏浚河道、搭桥通航,自古以来都是疏通水运,繁荣经济的重要举措。门静脉系是人体最大的、收集腹腔内不成对脏器(如脾、胰、肠等)血液回流的主干道,当它的血液回流受阻,如常见的肝硬化导致门脉系血液回流受阻,便会发生类似河道壅塞的情况。能否在堵塞的门静脉与体循环系统之间。 展开更多
关键词 肝脏搭桥术 tips 肝硬化 血液回流 门静脉系
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多模态影像融合技术在TIPS介入治疗中的研究及应用进展
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作者 谭文乐 吴敬玺 +1 位作者 李晓辉 段峰 《手术电子杂志》 2025年第4期1-5,共5页
多模态影像融合技术在介入治疗领域的应用日益受到重视,尤其是在经颈静脉肝内门体分流术(TIPS)中,该技术能够显著提升治疗的安全性和有效性。当前,TIPS介入治疗面临着术前评估不充分、术中导航不精准及术后监测不足等问题,这些问题直接... 多模态影像融合技术在介入治疗领域的应用日益受到重视,尤其是在经颈静脉肝内门体分流术(TIPS)中,该技术能够显著提升治疗的安全性和有效性。当前,TIPS介入治疗面临着术前评估不充分、术中导航不精准及术后监测不足等问题,这些问题直接影响了治疗效果和患者预后。研究表明多模态影像融合技术通过整合不同影像学方法的数据,能够为医师提供更全面的信息,改善术前规划,优化术中操作,增强术后评估的准确性。本文综述了多模态影像融合技术在TIPS介入治疗中的研究进展,重点探讨其在术前评估、术中导航及术后监测中的具体应用,同时分析了不同影像技术的优势与局限性。最后,展望了该领域未来的发展方向,以期推动临床实践的发展和提升患者的治疗效果。 展开更多
关键词 多模态影像融合技术 tips 介入治疗 影像学 应用进展
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O-band low loss and polarization insensitivity bilayer and double-tip edge coupler
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作者 Yuanjian Wan Yu Zhang Jian Wang 《Advanced Photonics Nexus》 2025年第2期31-38,共8页
Edge couplers,widely recognized for their efficiency and broad bandwidth,have gained significant attention as optical fiber-to-chip couplers.Silicon waveguides exhibit strong birefringence properties,resulting in subs... Edge couplers,widely recognized for their efficiency and broad bandwidth,have gained significant attention as optical fiber-to-chip couplers.Silicon waveguides exhibit strong birefringence properties,resulting in substantial polarization-dependent loss for edge couplers in the O-band.We introduce a bilayer and double-tip edge coupler designed to efficiently couple both transverse electric(TE)and transverse magnetic(TM)modes while maintaining compatibility with standard manufacturing processes used in commercial silicon photonics foundries.We have successfully designed and fabricated this edge coupler,achieving coupling losses of<1.52 dB∕facet for TE mode and 2 dB∕facet for TM mode when coupled with a lensed optical fiber[4-μmmode field diameter(MFD)]within the wavelength range of 1260 to 1360 nm. 展开更多
关键词 edge coupler integrated photonics optical fiber-to-chip coupling O-band optical communication
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Intraspecific trait variation shows that functional diversity decreases in tropical forest natural edges compared to forest interiors
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作者 Lucas DEZIDERIO SANTANA Jamir A.PRADO-JUNIOR +5 位作者 JoséHugo C.RIBEIRO Kelly M.G.PEREIRA TaináMAMEDE C.SILVA William DOS SANTOS RIBEIRO Fabrício ALVIM CARVALHO Eduardo VAN DEN BERG 《Journal of Mountain Science》 2025年第9期3214-3226,共13页
Functional traits are characteristics associated with the growth,reproduction,and survival of individuals.Studying them helps us understand how species traits drive ecosystem functioning.Thus,we evaluated the differen... Functional traits are characteristics associated with the growth,reproduction,and survival of individuals.Studying them helps us understand how species traits drive ecosystem functioning.Thus,we evaluated the differences in traits and functional diversity between forest edges and interiors,and how the inclusion of intraspecific trait variation affects the assessment of functional diversity in these habitats.We sampled 10 representative forest patches,and,in each patch,we established five plots on the edge and five inside the forest,collecting leaf functional traits,allometric and wood density for all species.We assessed functional diversity using functional richness(FRic),divergence(FDiv),and dispersion(FDis).To assess the impact of incorporating intraspecific variation when comparing trait values and functional diversity indices,we established two scenarios:one that excludes intraspecific variation and another that includes it.We found that the edge and interior harbor individuals with distinct functional traits that alleviate the inherent stress of each habitat.The edge was also found to be more selective in terms of the range of functional traits,resulting in lower functional diversity.Our findings demonstrated that habitats play an important role in intraspecific trait variation(ITV)and that statistically significant differences between habitats,in relation to traits and functional diversity,were better observed with the inclusion of intraspecific variation.Our study highlights the potential of using natural forest patches to understand the edge effect,regardless of habitat loss.Additionally,we emphasize the importance of incorporating ITV into functional diversity studies,especially those on a smaller scale that incorporate quantitative variables,to better understand and predict ecological patterns. 展开更多
关键词 Allometric traits Cloud forest edge effect edge-interior gradient Functional richness ITV
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Edge computing aileron mechatronics using antiphase hysteresis Schmitt trigger for fast flutter suppression
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作者 Tangwen Yin Dan Huang Xiaochun Zhang 《Control Theory and Technology》 2025年第1期153-160,共8页
An aileron is a crucial control surface for rolling.Any jitter or shaking caused by the aileron mechatronics could have catastrophic consequences for the aircraft’s stability,maneuverability,safety,and lifespan.This ... An aileron is a crucial control surface for rolling.Any jitter or shaking caused by the aileron mechatronics could have catastrophic consequences for the aircraft’s stability,maneuverability,safety,and lifespan.This paper presents a robust solution in the form of a fast flutter suppression digital control logic of edge computing aileron mechatronics(ECAM).We have effectively eliminated passive and active oscillating response biases by integrating nonlinear functional parameters and an antiphase hysteresis Schmitt trigger.Our findings demonstrate that self-tuning nonlinear parameters can optimize stability,robustness,and accuracy.At the same time,the antiphase hysteresis Schmitt trigger effectively rejects flutters without the need for collaborative navigation and guidance.Our hardware-in-the-loop simulation results confirm that this approach can eliminate aircraft jitter and shaking while ensuring expected stability and maneuverability.In conclusion,this nonlinear aileron mechatronics with a Schmitt positive feedback mechanism is a highly effective solution for distributed flight control and active flutter rejection. 展开更多
关键词 AILERON edge computing Flutter suppression MECHATRONICS Nonlinear hysteresis control Positive feedback
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Mach reflection and pressure/heating loads on V-shaped blunt leading edges with variable cross-sections and crotches
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作者 Tao ZHANG Xuhui ZHANG +3 位作者 Luoyu RAO Chongguang SHI Chengxiang ZHU Yancheng YOU 《Chinese Journal of Aeronautics》 2025年第1期271-285,共15页
The primary Mach Reflection(MR)and pressure/heating loads on V-shaped Blunt Leading Edges(VBLEs)with variable elliptic cross-sections and conic crotches are theoretically investigated in this study.The simplified cont... The primary Mach Reflection(MR)and pressure/heating loads on V-shaped Blunt Leading Edges(VBLEs)with variable elliptic cross-sections and conic crotches are theoretically investigated in this study.The simplified continuity method is used to forecast the shock configurations.The theoretical predictions and the numerical simulations for the Mach stem and the triple point as well as the curved shock accord well.Based on the theoretical model,an analysis of the impact of the axial ratio a/b of the cross-sectional shape and the eccentricity e of the crotch sweep path on shock structures is carried out.The shock configurations obtained from the theoretical model enable the derivation of the transition boundaries between the primary MR and the same family Regular Reflection(sRR).It is found that the increase of a/b and e can both facilitate the primary MR to sRR transition.The resulting transition and the corresponding generation of the wall pressure and heat flux are then investigated.The results indicate that higher values of the ratio a/b can significantly reduce the wall pressure and heating loads by inducing the primary MR to sRR transition.Conversely,the increase in the eccentricity e results in increased loads,despite causing the same transition. 展开更多
关键词 AERODYNAMICS Hypersonic flow Shock waves Heat flux V-shaped blunt leading edges
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Ensemble modelling for smart conservation strategies for forest reptile species at their range edges in Europe amidst climate change
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作者 Oksana Nekrasova Mihails Pupins +5 位作者 Volodymyr Tytar AndrisČeirāns Oleksii Marushchak ArtursŠkute Kathrin Theissinger Jean-Yves Georges 《Geography and Sustainability》 2025年第2期97-107,共11页
Reptile fauna should be considered a conservation objective,especially in respect of the impacts of climate change on their distribution and range’s dynamics.Investigating the environmental drivers of reptile species... Reptile fauna should be considered a conservation objective,especially in respect of the impacts of climate change on their distribution and range’s dynamics.Investigating the environmental drivers of reptile species richness and identifying their suitable habitats is a fundamental prerequisite to setting efficient long-term conservation measures.This study focused on geographical patterns and estimations of species richness for herpetofauna widely spread Z.vivipara,N.natrix,V.berus,A.colchica,and protected in Latvia C.austriaca,E.orbicularis,L.agilis inhabiting northern(model territory Latvia)and southern(model territory Ukraine)part of their European range.The ultimate goal was to designate a conservation network that will meet long-term goals for survival of the target species in the context of climate change.We used stacked species distribution models for creating maps depicting the distribution of species richness under current and future(by 2050)climates for marginal reptilepopulations.Using cluster analysis,we showed that this herpeto-complex can be divided into“widespread species”and“forest species”.For all forest species we predicted a climate-driven reduction in their distribution range both North(Latvia)and South(Ukraine).The most vulnerable populations of“forest species”tend to be located in the South of their range,as a consequence of northward shifts by 2050.By 2050 the greatest reduction in range is predicted for currently widely spread Z.vivipara(by 1.4 times)and V.berus(by 2.2 times).In terms of designing an effective protected-area network,these results permit to identify priority conservation areas where the full ensemble of selected reptile species can be found,and confirms the relevance of abioticmulti-factor GIS-modelling for achieving this goal. 展开更多
关键词 edge of area Stacked species distribution models Suitable habitats Priority conservation areas
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肝硬化门静脉高压并发上消化道出血应用TIPS治疗对其治疗成功率的影响
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作者 张力学 《中文科技期刊数据库(引文版)医药卫生》 2025年第6期086-089,共4页
为了保证肝硬化门静脉高压并发上消化道出血患者获得针对性治疗,本次主要探索不同的治疗方式对患者的治疗效果,突出分析肝硬化门静脉高压并发上消化道出血在TIPS结合GCVE治疗下获得的成果,为患者病情改善提供科学支持与参考依据。方法 ... 为了保证肝硬化门静脉高压并发上消化道出血患者获得针对性治疗,本次主要探索不同的治疗方式对患者的治疗效果,突出分析肝硬化门静脉高压并发上消化道出血在TIPS结合GCVE治疗下获得的成果,为患者病情改善提供科学支持与参考依据。方法 选择河北省卢龙县医院2023年1月到2024年10月的50例患者进行研究,以随机数字表法作为基本的分组方法,其中一组是对照组,另外一组是试验组,前者实施传统治疗,后者的主要治疗方式是TIPS+GCVE,并比较不同的治疗方法对比后的相关数据,例如治疗成功率、血流动力学等。结果 两组在治疗成功率与肝功能等指标的比较上,均有显著差别,且符合统计学软件的要求。结论 TIPS对肝硬化门静脉高压并发上消化道出血的治疗,对调整患者的血流动力学指标与肝功能相关指标有积极作用,增加治疗成功率,且尽可能降低对患者肝功能的损伤,使患者获得相对安全且可靠的治疗服务,其在临床上有一定的应用意义与推荐价值。 展开更多
关键词 肝硬化门静脉高压并发上消化道出血 tips 治疗成功率
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Essential juniperoil-induced resistance of juniper against Diplodia tip blight in Pinus sylvestris var.mongolica
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作者 Aomen He Shixian Liao +3 位作者 Jing Guo Teng Ma Xiaowei Chen Boru Zhou 《Journal of Forestry Research》 2026年第2期275-289,共15页
Diplodia tip blight,caused by Diplodia sapinea,is a global pine necrotic disease causing heavy economic losses to the pine industry.Chemical control,its main current management,easily induces pathogen resistance and e... Diplodia tip blight,caused by Diplodia sapinea,is a global pine necrotic disease causing heavy economic losses to the pine industry.Chemical control,its main current management,easily induces pathogen resistance and environmental pollution,which biological control avoids.This study investigated juniper essential oil’s efficacy against the disease on Mongolian Scots pine(Pinus sylvestris var.mongolica)and its induced resistance mechanisms via pot experiments,physiological assays(defense enzyme activities,resistant substances)and metabolomic sequencing(secondary metabolites).Results showed varied efficacy:three foliar sprays of 10μL mL^(-1) oil achieved the best control phenylalanine ammonia-lyase(PAL),polyphenol oxidase(82.9%).The 20μL mL^(-1) treatment significantly increased(PPO)activities,and contents of lignin,flavonoids and total phenolics.Metabolomic analysis showed 326 upregulated and 527 downregulated different metabolites in essential oilinduced and pathogen-inoculated pines,compared to 483 upregulated and 277 downregulated metabolites in noninduced but inoculated pines.The differentially expressed metabolites in treated pines were primarily enriched in pathways related to amino acid metabolism and plant secondary metabolite biosynthesis,with notably increased expression levels of ferulic acid,scopoletin,pipecolic acid,D-proline,and DL-arginine.Therefore,juniper essential oil protects against D.sapinea by inducing systemic acquired resistance in Mongolian Scots pine.In conclusion,juniper essential oil controls D.sapinea by inducing systemic acquired resistance(SAR)in Mongolian Scots pine,clarifying the molecular mechanism and supporting biological control of the disease. 展开更多
关键词 Diplodia tip blight Biological control Induced resistance Metabolomics Plant defense compounds
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Radiation hardness of 1.2 kV SiC power devices with advanced edge termination structures under proton irradiation
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作者 Sangyeob Kim Jeongtae Kim +3 位作者 Dong-Seok Kim Hyuncheol Bae Min-Woo Ha Ogyun Seok 《Journal of Semiconductors》 2026年第1期83-89,共7页
This work presents a systematic analysis of proton-induced total ionizing dose(TID)effects in 1.2 k V silicon carbide(SiC)power devices with various edge termination structures.Three edge terminations including ring-a... This work presents a systematic analysis of proton-induced total ionizing dose(TID)effects in 1.2 k V silicon carbide(SiC)power devices with various edge termination structures.Three edge terminations including ring-assisted junction termination extension(RA-JTE),multiple floating zone JTE(MFZ-JTE),and field limiting rings(FLR)were fabricated and irradiated with45 Me V protons at fluences ranging from 1×10^(12) to 1×10^(14) cm^(-2).Experimental results,supported by TCAD simulations,show that the RA-JTE structure maintained stable breakdown performance with less than 1%variation due to its effective electric field redistribution by multiple P+rings.In contrast,MFZ-JTE and FLR exhibit breakdown voltage shifts of 6.1%and 15.2%,respectively,under the highest fluence.These results demonstrate the superior radiation tolerance of the RA-JTE structure under TID conditions and provide practical design guidance for radiation-hardened Si C power devices in space and other highradiation environments. 展开更多
关键词 SIC proton irradiation edge termination radiation hardness TID effects
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ES-YOLO:Edge and Shape Fusion-Based YOLO for Tra.c Sign Detection
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作者 Weiguo Pan Songjie Du +2 位作者 Bingxin Xu Bin Zhang Hongzhe Liu 《Computers, Materials & Continua》 2026年第4期2127-2145,共19页
Traffic sign detection is a critical component of driving systems.Single-stage network-based traffic sign detection algorithms,renowned for their fast detection speeds and high accuracy,have become the dominant approa... Traffic sign detection is a critical component of driving systems.Single-stage network-based traffic sign detection algorithms,renowned for their fast detection speeds and high accuracy,have become the dominant approach in current practices.However,in complex and dynamic traffic scenes,particularly with smaller traffic sign objects,challenges such as missed and false detections can lead to reduced overall detection accuracy.To address this issue,this paper proposes a detection algorithm that integrates edge and shape information.Recognizing that traffic signs have specific shapes and distinct edge contours,this paper introduces an edge feature extraction branch within the backbone network,enabling adaptive fusion with features of the same hierarchical level.Additionally,a shape prior convolution module is designed to replaces the first two convolutional modules of the backbone network,aimed at enhancing the model's perception ability for specific shape objects and reducing its sensitivity to background noise.The algorithm was evaluated on the CCTSDB and TT100k datasets,and compared to YOLOv8s,the mAP50 values increased by 3.0%and 10.4%,respectively,demonstrating the effectiveness of the proposed method in improving the accuracy of traffic sign detection. 展开更多
关键词 Traffic sign edge information shape prior feature fusion object detection
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Lightweight Multi-Agent Edge Framework for Cybersecurity and Resource Optimization in Mobile Sensor Networks
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作者 Fatima Al-Quayed 《Computers, Materials & Continua》 2026年第1期919-934,共16页
Due to the growth of smart cities,many real-time systems have been developed to support smart cities using Internet of Things(IoT)and emerging technologies.They are formulated to collect the data for environment monit... Due to the growth of smart cities,many real-time systems have been developed to support smart cities using Internet of Things(IoT)and emerging technologies.They are formulated to collect the data for environment monitoring and automate the communication process.In recent decades,researchers have made many efforts to propose autonomous systems for manipulating network data and providing on-time responses in critical operations.However,the widespread use of IoT devices in resource-constrained applications and mobile sensor networks introduces significant research challenges for cybersecurity.These systems are vulnerable to a variety of cyberattacks,including unauthorized access,denial-of-service attacks,and data leakage,which compromise the network’s security.Additionally,uneven load balancing between mobile IoT devices,which frequently experience link interferences,compromises the trustworthiness of the system.This paper introduces a Multi-Agent secured framework using lightweight edge computing to enhance cybersecurity for sensor networks,aiming to leverage artificial intelligence for adaptive routing and multi-metric trust evaluation to achieve data privacy and mitigate potential threats.Moreover,it enhances the efficiency of distributed sensors for energy consumption through intelligent data analytics techniques,resulting in highly consistent and low-latency network communication.Using simulations,the proposed framework reveals its significant performance compared to state-of-the-art approaches for energy consumption by 43%,latency by 46%,network throughput by 51%,packet loss rate by 40%,and denial of service attacks by 42%. 展开更多
关键词 Artificial intelligence CYBERSECURITY edge computing Internet of Things threat detection
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