Objective To systematically evaluate the overall characteristics and quality of literature on economic evaluation of drugs for type 2 diabetes,and to provide recommendations for future research and related decision-ma...Objective To systematically evaluate the overall characteristics and quality of literature on economic evaluation of drugs for type 2 diabetes,and to provide recommendations for future research and related decision-making.Methods The economic evaluation literature on drugs for type 2 diabetes based on the Chinese population were searched from CNKI,Wanfang,VIP and PubMed databases.The literature that met the inclusion criteria was selected,and the key research elements were extracted.Meanwhile,the quality of health economics studies(QHES)was used to evaluate the quality of the literature.Results and Conclusion A total of 325 articles(296 in Chinese and 29 in English)were included.Most of the studies were conducted by medical institutions(247 articles,76.0%)and they used cost-effectiveness analysis(295 articles,90.8%).However,most of the included literature did not report study perspective(267 articles,90.2%).The average QHES score of the included literature was 57.29,and the quality of the literature was concentrated in“low quality”(123 articles,37.8%)and“average quality”(138 articles,42.5%).Literature published in English journals,or using modeling methods,or from universities had relatively higher quality.The quality of economic evaluation literature on drugs for type 2 diabetes based on the Chinese population is generally low at present.There are many problems,such as single research institutions and methods,lack of research perspectives,and no sensitivity analysis.展开更多
The research conducted investigation and survey on 186 farm households in 2014 and carried out economic evaluation on ＂planting three to produce four＂ highyielding project of super hybrid rice. The results showed th...The research conducted investigation and survey on 186 farm households in 2014 and carried out economic evaluation on ＂planting three to produce four＂ highyielding project of super hybrid rice. The results showed that the project of ＂planting three to produce four＂ performed significantly in terms of increasing yields and incomes. For example, per unit area yield of one-season late hybrid rice and middleseason hybrid rice proved the highest, and net income from middle-season rice in Longhui was the highest. It is obvious that to increase per unit yield is key for improving net incomes and to reduce machine fees and worker fees is crucial for decreasing fees.展开更多
Based on multi-source data,this paper evaluated the economic value of ecological services in the Yeyahu Wetland Nature Reserve,Beijing,China.The ecological services of wetland included gas regulation,water quality im-...Based on multi-source data,this paper evaluated the economic value of ecological services in the Yeyahu Wetland Nature Reserve,Beijing,China.The ecological services of wetland included gas regulation,water quality im-provement,biodiversity maintenance,erosion control,water supply,recreational opportunity,raw material supply and existence value.Multiple conventional evaluation methods were used to calculate the value of eight wetland services.The results showed that significant values came from biodiversity maintenance and recreational opportunity.The main reasons were as follows.Firstly,Yeyahu Wetland Nature Reserve was the habitat for migrant birds,and government had payed more efforts to protect precious birds.Secondly,the population is large in Beijing.People enjoyed going outside and enjoyed the natural and artificial wetland scenes.At the same time,most people were prepared to pay for wetland conservation.The decline of vegetation cover made the economic value of erosion control the lowest.While the shrink of water resource and the deteriorative water quality caused the economic value of water supply lower.The evaluation results could help decision-makers understand the present status of the Yeyahu Wetland Nature Reserve and provide a scientific basis for strategic decision.展开更多
Because forecasting a development program during the target selection phase of exploration for coalbed methane （CBM） is impossible, the conventional method that relies on a conceptual （or detailed） development pro...Because forecasting a development program during the target selection phase of exploration for coalbed methane （CBM） is impossible, the conventional method that relies on a conceptual （or detailed） development pro- gram cannot be used during the economic evaluation of CBM resources. Hence, this study focuses on establishing an economic evaluation model based on the characteristics of the target selection phase. The discounted cashflow method is applied to the construction of the model with the assumption that there is a uniform distribution of produc- tion wells. The computational error generated by the assumption is corrected by introducing a correction factor based on the production profile of single CBM wells. The case study demonstrates that the blocks lacking economic value can be screened out, and the most advantageous targets can be found by computing the resource values in the best- and worst-case scenarios. This technique can help to reduce wasted investments and improve the quality of decision-making in selecting targets for exploration.展开更多
Gastric cancer is a global public health burden, nearly one million new cases are diagnosed per year worldwide, of which 44% of cases occur in China. The prognosis of gastric cancer varies remarkably by the stage of c...Gastric cancer is a global public health burden, nearly one million new cases are diagnosed per year worldwide, of which 44% of cases occur in China. The prognosis of gastric cancer varies remarkably by the stage of cancer, and most of the patients in China are diagnosed at advanced stages, resulting in poor prognoses. Effective strategies to reduce the burden of gastric cancer include primary prevention through testing and treatment of Helicobacter pylori(H. pylori) and secondary prevention by screening and early detection. Although many countries have issued management guidelines and consensus reports concerning these strategies, the limited availability of healthcare resources often precludes their widespread implementation. Therefore, assessing the costs, benefits, and harms of population-based intervention measures through health economic evaluation is necessary for informed health policy decisions. Accordingly, we synthesize management approaches from different countries on H. pylori eradication and endoscopic screening, and also summarize recent advancements in health economic evaluations on population-based preventive strategies. The goal of the review is to provide empirical evidence supporting optimal resource allocation, maximizing benefits for the population, and ultimately reducing the burden of gastric cancer.展开更多
The rice-duck ecological system is one of the major practices of the traditional Chinese agriculture. A study on the effect of reducing methane emission using this practice provided theoretical and practical basis for...The rice-duck ecological system is one of the major practices of the traditional Chinese agriculture. A study on the effect of reducing methane emission using this practice provided theoretical and practical basis for further development and utilization of this classical agricultural technique. The effect of reducing methane emission and the economic benefits of rice-duck ecological system were studied by carrying out a field experiment and by using economic methodology. The daily variation of CH4 emission in late rice paddy field was basically consistent with the daily variation of atmospheric temperature. The highest emission occurred at the full tillering stage of late rice with a rate of 24.1 or 32.2 or 40.5 mg m^-2 h^-1 in no-tillage area with duck and no-tillage area without duck and conventional-tillage area without duck, respectively. The inhibition of methane emission was apparently effective in the rice-duck ecological system during the initial tillering stage and the full tillering stage. Compared to the no-tillage area without duck, methane emission decreased by 2.333 g m^-2. Compared to the conventional-tillage area without duck, methane emission decreased by 4.723 g m^-2. During the production period of late rice, the amount of methane emission in no-tillage area with duck was 3.373 g m^-2 lesser than that of no-tillage area without duck, and 5.59 g m^-2 less than that of conventional-tillage without duck area. The economic significance was analyzed. Farmers adopting the rice-duck ecological system obtained 2 166 and 4 207 RMB yuan ha^-1 more income than those who adopted a no-tillage without duck technique or conventional-tillage without duck technique, respectively. In addition to the reduction of the environmental pollution by methane emission, the farmers who adopted the rice-duck ecological system achieved economic benefits of 5 000 RMB yuan ha^-1, which was 2 206 and 4 274 RMB yuan ha^-1 more than those who adopted a no-tillage without duck technique and a conventional-tillage without duck technique, respectively. The rice-duck ecological system not only increased the economic benefits for farmers, but also reduced methane emission in rice paddy field. A sustainable agricultural production mode was formed.展开更多
This study aims at determining the optimal CO2 separation technology for Chinese refineries, based on current available technologies, by the method of comprehensive evaluation. Firstly, according to the characteristic...This study aims at determining the optimal CO2 separation technology for Chinese refineries, based on current available technologies, by the method of comprehensive evaluation. Firstly, according to the characteristics of flue gas from Chinese refineries, three feasible CO2 separation technologies are selected. These are pressure swing adsorption （PSA）, chemical absorption （CA）, and membrane absorption （MA）. Secondly, an economic assessment of these three techniques is carried out in accordance with cash flow analysis. The results show that these three techniques all have economic feasibility and the PSA technique is the best. Finally, to further optimize the three techniques, a two-level fuzzy comprehensive evaluation model is established, including economic, technological, and environmental factors. Considering all the factors, PSA is optimal for Chinese refineries, followed by CA and MA. Therefore, to reduce Chinese refineries carbon emission, it is suggested that CO2 should be captured from off-gases using PSA.展开更多
Objective:This study evaluated the feasibility of different cervical cancer screening strategies in urban China.Methods:A Markov model was constructed to simulate a hypothetical cohort of 100,000 females aged 30-59 ye...Objective:This study evaluated the feasibility of different cervical cancer screening strategies in urban China.Methods:A Markov model was constructed to simulate a hypothetical cohort of 100,000 females aged 30-59 years in a 20-year period.Screening strategies included liquid-based cytology(LBC)every three years,human papillomavirus(HPV)DNA testing every three and five years,respectively,and a combination of HPV DNA testing and LBC(HPV+LBC)every three and five years,respectively.Model outcomes included cumulative incidence over 20 years,cumulative risk of cervical cancer,costs,life year saved(LYS),quality-adjusted life years(QALYs)and benefits.The cost-effectiveness ratios(CERs),incremental cost-effectiveness ratios(ICERs),costutility ratios(CURs),and benefit-cost ratios(BCRs)were used as outcomes in the health economic evaluation analysis.Univariate sensitivity analyses were performed to examine the stability of the results.Results:The cumulative incidence of the five screening strategies ranged from 833.02 to 1,158.07 cases per100,000 females.HPV DNA testing was most effective in reducing the cumulative risk of cervical cancer,saving life years and QALYs and gaining benefits.The CERs of HPV DNA testing every three and five years,and LBC every three years were considered to be very cost-effective if they were below China's GDP per capita.The CERs of HPV+LBC were considered to be cost-effective if they were below three times GDP per capita.The incremental cost-effectiveness analysis showed that HPV DNA testing every three and five years,LBC every three years and HPV+LBC every five years were dominant strategies.Conclusions:The findings of this study indicated that HPV DNA testing every five years or LBC every three years should be recommended in urban China.展开更多
OBJECTIVE:To analyze the cost effect of surrounding acupuncture plus electric acupuncture,cotton-sheet moxibustion,puncturing with red-hot needles,tapping plus cupping on herpes zoster.METHODS:Five hundred patients wi...OBJECTIVE:To analyze the cost effect of surrounding acupuncture plus electric acupuncture,cotton-sheet moxibustion,puncturing with red-hot needles,tapping plus cupping on herpes zoster.METHODS:Five hundred patients with herpes zoster were randomly divided into group A(surrounding acupuncture plus electric acupuncture),group B(cotton-sheet moxibustion),group C(puncturing with red-hot needles),group D(tapping plus cupping),and group E(Western medicine).The treatment was carried out twice a day in group E and once a day in the other four groups.The curative effect was observed on the 10th day of treatment;the cost was calculated for the five therapies,and the cost-effect ratio(C/E) and increment ratio(△ C/△ E) were analyzed.RESULTS:After the 10-day treatment,there was no statistical difference(P>0.05) in the curative effect among the five groups.Pain being alleviated one day faster than in group E amounted to a saving of RMB 21.90 yuan in group A,a saving of RMB 21.87 yuan in group B,a saving of RMB 26.00 yuan in group C,and a saving of RMB 20.23 yuan in group D.Compared with group C,the values of △ C/△ E were RMB 1.55,2.81,and 0.21 yuan in groups A,B,and D,respectively.CONCLUSIONS:The curative effect in groups A,B,C,and D was similar to that in group E,but the C/E was better than in group E.展开更多
The main purpose of this study is to give evaluation of ecological services of Jilin Province, Northeast China. To take this value into decision-making and GDP accounting system is considered to be one of the economic...The main purpose of this study is to give evaluation of ecological services of Jilin Province, Northeast China. To take this value into decision-making and GDP accounting system is considered to be one of the economic solutions for ecological problems. The evaluation is based on the methods proposed by COSTANZA et al., and some modifications about unit value of forest and cropland system were made according to the real characters of ecosystem, climate, natural conditions etc., in Jilin Province. Total value of ecosystem services is about 554.404x10(9) yuan(RMB)/a, which is about 4.9 times of GDP of the corresponding period. The results of this study could be used as a fundamental work for the construction of ecological province, which was carried out from 2001, and could provide ecological information for decision-making. Furthermore, the necessities for the further studies on the evaluation of ecological services and natural capital were discussed.展开更多
The environment impact of the coal resources mining was analyzed. The method of economic evaluation for the coal mining was established to analyze land destruction. The opportunity cost method was used to quantitative...The environment impact of the coal resources mining was analyzed. The method of economic evaluation for the coal mining was established to analyze land destruction. The opportunity cost method was used to quantitatively analyze and estimate the economic loss of the land destruction by coal mining. At the same time, the dump land reclamation of the Yuanbaoshan Open Pit was taken as an example to evaluate environmental and economical benefit with the method of economic evaluation for the coal mining areas land reclamation.展开更多
Energy storage system is an important means to improve the flexibility and safety of traditional power system,but it has the problem of high cost and unclear value recovery path.In this paper,the typical application s...Energy storage system is an important means to improve the flexibility and safety of traditional power system,but it has the problem of high cost and unclear value recovery path.In this paper,the typical application scenarios of energy storage system are summarized and analyzed from the perspectives of user side,power grid side and power generation side.Based on the typical application scenarios,the economic benefit assessment framework of energy storage system including value,time and efficiency indicators is proposed.Typical battery energy storage projects are selected for economic benefit calculation according to different scenarios,and key factors are selected for sensitivity analysis.Finally,the key factors affecting economic benefit of the energy storage system are analyzed.展开更多
Rice straw is a rice by-product, which is currently mostly wasted in Vietnam, in particular in the Mekong delta. At present, the cost of straw gathering is increasing because of the increased use of combine harvesters...Rice straw is a rice by-product, which is currently mostly wasted in Vietnam, in particular in the Mekong delta. At present, the cost of straw gathering is increasing because of the increased use of combine harvesters. High labor cost and lack of labor makes manual collection unfeasible. Farmers therefore often just burn it, which causes pollution, increased greenhouse gas emissions and loss of opportunities to value add. An economic and environmental evaluation and technical field testing of a straw baler with 4 ha/day capacity was therefore conducted in Long An province. During the field testing data on the gathering capacity, fuel consumption, labor requirement and other cost items were collected. The test results showed that the baling cost is US$19.0 per ton of rice straw, the pay-back period of 2. 1 years and the internal rate of return of 38%. In addition to the baling cost, the transportation cost varies from US$24 for a distance of 100 km to US$32 for 150 km. The benefits of the machine are not only economical but also include the reduction of field burning.展开更多
The publication of ISO 15686-5 is significant for studies related to the life-cycle costs of buildings. Among the many economic evaluation methods, the NPV method is recommended for use by this standard. This stu...The publication of ISO 15686-5 is significant for studies related to the life-cycle costs of buildings. Among the many economic evaluation methods, the NPV method is recommended for use by this standard. This study explains the concept and method of PV, and then provides an explanation of the concept and method of NPV, and points out the limitations in the practical application of the method.展开更多
China is rich in tight sandstone gas resources(“tight gas”for short).For example,the Sulige Gasfield in the Ordos Basin and the Upper Triassic Xujiahe Fm gas reservoir in the Sichuan Basin are typical tight gas rese...China is rich in tight sandstone gas resources(“tight gas”for short).For example,the Sulige Gasfield in the Ordos Basin and the Upper Triassic Xujiahe Fm gas reservoir in the Sichuan Basin are typical tight gas reservoirs.In the past decade,tight gas reserve and production both have increased rapidly in China,but tight gas reservoirs are always managed as conventional gas reservoirs without effective fiscal,taxation and policy supports.The potential of sustainable tight gas production increase is obviously restricted.The tight gas development projects represented by the Sulige Gasfield have failed to make profit for a long period,and especially tight gas production has presented a slight decline since 2015.In this paper,a new economic evaluation method was proposed for tight gas development projects.The new method was designed to verify the key parameters(e.g.production decline rate and single-well economic service life)depending on tight gas development and production characteristics,and perform the depreciation by using the production method.Furthermore,the possibility that the operation cost may rise due to pressure-boosting production and intermittent opening of gas wells is considered.The method was used for the tight gas development project of Sulige Gasfield,showing that its profit level is much lower than the enterprise's cost level of capital.In order to support a sustainable development of tight gas industry in China,it is recommended that relevant authorities issue value-added tax(VAT)refund policy as soon as possible.It is necessary to restore the non-resident gas gate price of the provinces where tight gas is produced to the fair and reasonable level in addition to the fiscal subsidy of CNY0.24/m^(3),or offer the fiscal subsidy of CNY0.32/m^(3) directly based on the on-going gate price.With these support policies,tax income is expected to rise directly,fiscal expenditure will not increase,and gas consumption cost in China will be significantly cut down.展开更多
Objective To evaluate the economy of detecting gastric cancer by electronic gastroscope in Chinese natural population of different ages and genders.Methods A Markov model was constructed for the population,including b...Objective To evaluate the economy of detecting gastric cancer by electronic gastroscope in Chinese natural population of different ages and genders.Methods A Markov model was constructed for the population,including both men and women of different ages.The model cycle was one year and the simulation time was 60 years.The cost-effectiveness of electronic gastroscopy in detecting gastric cancer of general population in China was analyzed from the perspective of the whole society,and the stability of the results was verified by sensitivity analysis.Results and Conclusion For the general population,the incremental cost-effectiveness ratio(ICER)of gastric cancer screening from the age of 50 is 50143 yuan/QALY(quality-adjusted life-year),which is less than two times of per capita gross domestic product(GDP)compared with the screening from the age of 55.For men who start gastric cancer screening at the age of 50,the ICER is 38525 yuan/QALY,which is less than two times of per capita GDP,and it is economical.For women who start the screening from the age of 55,the ICER is 47814 yuan/QALY,which is less than two times of per capita GDP,so it is economical.The results of sensitivity analysis are consistent with the conclusions of basic analysis,and the results of basic analysis are stable.For the general population,it is more economical to start gastric cancer screening from the age of 50,while for men and women,it is more economical to start gastric cancer screening from the age of 50 and 55,respectively.展开更多
Hydraulic fracturing is among the approaches used to optimize production from a gas condensate reservoir. A detailed economic analysis is required to evaluate the profitability and feasibility of hydraulic fracturing ...Hydraulic fracturing is among the approaches used to optimize production from a gas condensate reservoir. A detailed economic analysis is required to evaluate the profitability and feasibility of hydraulic fracturing as an optimization option in a gas condensate reservoir operating below dewpoint. The objective of this research is to evaluate the economic benefits derivable from the use of hydraulic fracturing to improve gas and liquid recovery from a gas condensate reservoir operating below dewpoint. This research considers the use of four profit indicators to ascertain the profitability of hydraulic fracturing in a gas condensate reservoir operating below dewpoint by increasing the fracture halflength, fracture width and fracture permeability. The production data of the reservoir was obtained and the economic calculations done on excel spreadsheet and plots generated. The four profit indicators considered in the research are Net Present Value, Payout, Discounted Cash Flow Rate of Return and Profit per Dollar Invested. The economic justification was done by carrying out a comparative economic analysis from the result obtained when the reservoir of study was unfractured with that obtained when the reservoir was fractured at various fracture parameters. The economic analysis was done considering a royalty and tax rate of 18.5% and 30% respectively and a gas price of $2/MSCF and condensate price of $30/bbl. This is done so as to find out if the additional cost of hydraulic fracturing can be offset by the recovery from the reservoir when its pressure declined below dewpoint. The result obtained showed that the additional recovery due to hydraulic fracturing by increasing the fracture halflength, fracture width and fracture permeability was not enough to justify the application of hydraulic fracturing when the reservoir pressure declined below dewpoint.展开更多
Taking the economic evaluation of a highway with international bank loan in Guangxi mountainous and hilly areas as an example, this paper summarizes the characteristics of economic evaluation of international bank loa...Taking the economic evaluation of a highway with international bank loan in Guangxi mountainous and hilly areas as an example, this paper summarizes the characteristics of economic evaluation of international bank loan highway projects, and puts forward the economic evaluation model of international bank loan highway projects, which can provide reference for other international loan highway construction projects.展开更多
At this stage, China is vigorously promoting the reform of the supply-side structure to promote the transformation and upgrading of the economy. In this process, the project investment decision of the enterprise plays...At this stage, China is vigorously promoting the reform of the supply-side structure to promote the transformation and upgrading of the economy. In this process, the project investment decision of the enterprise plays a very important role, which affects the development of the enterprise. It is necessary to apply the financial and economic evaluation method in a timely manner to identify the risks in the project investment decision and improve the safety of the enterprise development. Based on this, this paper analyzes the financial and economic evaluation method from three aspects of connotation, significance and classification, clarifies the analysis that should be paid attention to in the application process of this method, and explains the specific application, in order to provide reference for the follow-up research in this field.展开更多
Fluoropyrimidines(FP),including 5-fluorouracil and its prodrug capecitabine,are commonly employed in treating various solid tumors.Nonetheless,their use is frequently constrained by severe toxicities in 20%-30%of pati...Fluoropyrimidines(FP),including 5-fluorouracil and its prodrug capecitabine,are commonly employed in treating various solid tumors.Nonetheless,their use is frequently constrained by severe toxicities in 20%-30%of patients.Pharmacogenetic testing for dihydropyrimidine dehydrogenase(DPYD)deficiency,based on DPYD polymorphisms,has notably decreased severe adverse events,improving the safety of FP therapy.A recent D'Amato et al study evaluated the prevalence of DPYD polymorphisms and their effect on FP tolerability among Italian patients with gastrointestinal cancers.Although this study provided important insights into the significance of DPYD testing,its retrospective nature,inconsistency in testing DPYD variants,and lack of consideration for socioeconomic and confounding factors showed considerable limitations.Expanding the screening to include DPYD variants,addressing confounding biases through robust statistical analyses,and implementing prospective studies are critical next steps to strengthen the clinical evidence.Furthermore,the absence of a comprehensive cost-effectiveness analysis highlights the need for further financial assessments to advocate for broader implementation.We emphasized integrating DPYD-guided dosing,pre-treatment genetic counseling,and standardized testing procedures into clinical practice to improve patient outcomes and minimize treatment-related toxicities.展开更多
文摘Objective To systematically evaluate the overall characteristics and quality of literature on economic evaluation of drugs for type 2 diabetes,and to provide recommendations for future research and related decision-making.Methods The economic evaluation literature on drugs for type 2 diabetes based on the Chinese population were searched from CNKI,Wanfang,VIP and PubMed databases.The literature that met the inclusion criteria was selected,and the key research elements were extracted.Meanwhile,the quality of health economics studies(QHES)was used to evaluate the quality of the literature.Results and Conclusion A total of 325 articles(296 in Chinese and 29 in English)were included.Most of the studies were conducted by medical institutions(247 articles,76.0%)and they used cost-effectiveness analysis(295 articles,90.8%).However,most of the included literature did not report study perspective(267 articles,90.2%).The average QHES score of the included literature was 57.29,and the quality of the literature was concentrated in“low quality”(123 articles,37.8%)and“average quality”(138 articles,42.5%).Literature published in English journals,or using modeling methods,or from universities had relatively higher quality.The quality of economic evaluation literature on drugs for type 2 diabetes based on the Chinese population is generally low at present.There are many problems,such as single research institutions and methods,lack of research perspectives,and no sensitivity analysis.
文摘The research conducted investigation and survey on 186 farm households in 2014 and carried out economic evaluation on ＂planting three to produce four＂ highyielding project of super hybrid rice. The results showed that the project of ＂planting three to produce four＂ performed significantly in terms of increasing yields and incomes. For example, per unit area yield of one-season late hybrid rice and middleseason hybrid rice proved the highest, and net income from middle-season rice in Longhui was the highest. It is obvious that to increase per unit yield is key for improving net incomes and to reduce machine fees and worker fees is crucial for decreasing fees.
基金Under the auspices of National Natural Science Foundation of China (No. 40771170)Beijing Municipal Natural Science Foundation (No. 8082010)
文摘Based on multi-source data,this paper evaluated the economic value of ecological services in the Yeyahu Wetland Nature Reserve,Beijing,China.The ecological services of wetland included gas regulation,water quality im-provement,biodiversity maintenance,erosion control,water supply,recreational opportunity,raw material supply and existence value.Multiple conventional evaluation methods were used to calculate the value of eight wetland services.The results showed that significant values came from biodiversity maintenance and recreational opportunity.The main reasons were as follows.Firstly,Yeyahu Wetland Nature Reserve was the habitat for migrant birds,and government had payed more efforts to protect precious birds.Secondly,the population is large in Beijing.People enjoyed going outside and enjoyed the natural and artificial wetland scenes.At the same time,most people were prepared to pay for wetland conservation.The decline of vegetation cover made the economic value of erosion control the lowest.While the shrink of water resource and the deteriorative water quality caused the economic value of water supply lower.The evaluation results could help decision-makers understand the present status of the Yeyahu Wetland Nature Reserve and provide a scientific basis for strategic decision.
基金funded by the Beijing Natural Science Foundation (9144033)the National Social Science Fund for Major Projects (11&ZD164)
文摘Because forecasting a development program during the target selection phase of exploration for coalbed methane （CBM） is impossible, the conventional method that relies on a conceptual （or detailed） development pro- gram cannot be used during the economic evaluation of CBM resources. Hence, this study focuses on establishing an economic evaluation model based on the characteristics of the target selection phase. The discounted cashflow method is applied to the construction of the model with the assumption that there is a uniform distribution of produc- tion wells. The computational error generated by the assumption is corrected by introducing a correction factor based on the production profile of single CBM wells. The case study demonstrates that the blocks lacking economic value can be screened out, and the most advantageous targets can be found by computing the resource values in the best- and worst-case scenarios. This technique can help to reduce wasted investments and improve the quality of decision-making in selecting targets for exploration.
基金supported in part by the Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support (No. ZLRK202325)a grant from National Key R&D Program of China (No. 2018YFC 1313105)。
文摘Gastric cancer is a global public health burden, nearly one million new cases are diagnosed per year worldwide, of which 44% of cases occur in China. The prognosis of gastric cancer varies remarkably by the stage of cancer, and most of the patients in China are diagnosed at advanced stages, resulting in poor prognoses. Effective strategies to reduce the burden of gastric cancer include primary prevention through testing and treatment of Helicobacter pylori(H. pylori) and secondary prevention by screening and early detection. Although many countries have issued management guidelines and consensus reports concerning these strategies, the limited availability of healthcare resources often precludes their widespread implementation. Therefore, assessing the costs, benefits, and harms of population-based intervention measures through health economic evaluation is necessary for informed health policy decisions. Accordingly, we synthesize management approaches from different countries on H. pylori eradication and endoscopic screening, and also summarize recent advancements in health economic evaluations on population-based preventive strategies. The goal of the review is to provide empirical evidence supporting optimal resource allocation, maximizing benefits for the population, and ultimately reducing the burden of gastric cancer.
文摘The rice-duck ecological system is one of the major practices of the traditional Chinese agriculture. A study on the effect of reducing methane emission using this practice provided theoretical and practical basis for further development and utilization of this classical agricultural technique. The effect of reducing methane emission and the economic benefits of rice-duck ecological system were studied by carrying out a field experiment and by using economic methodology. The daily variation of CH4 emission in late rice paddy field was basically consistent with the daily variation of atmospheric temperature. The highest emission occurred at the full tillering stage of late rice with a rate of 24.1 or 32.2 or 40.5 mg m^-2 h^-1 in no-tillage area with duck and no-tillage area without duck and conventional-tillage area without duck, respectively. The inhibition of methane emission was apparently effective in the rice-duck ecological system during the initial tillering stage and the full tillering stage. Compared to the no-tillage area without duck, methane emission decreased by 2.333 g m^-2. Compared to the conventional-tillage area without duck, methane emission decreased by 4.723 g m^-2. During the production period of late rice, the amount of methane emission in no-tillage area with duck was 3.373 g m^-2 lesser than that of no-tillage area without duck, and 5.59 g m^-2 less than that of conventional-tillage without duck area. The economic significance was analyzed. Farmers adopting the rice-duck ecological system obtained 2 166 and 4 207 RMB yuan ha^-1 more income than those who adopted a no-tillage without duck technique or conventional-tillage without duck technique, respectively. In addition to the reduction of the environmental pollution by methane emission, the farmers who adopted the rice-duck ecological system achieved economic benefits of 5 000 RMB yuan ha^-1, which was 2 206 and 4 274 RMB yuan ha^-1 more than those who adopted a no-tillage without duck technique and a conventional-tillage without duck technique, respectively. The rice-duck ecological system not only increased the economic benefits for farmers, but also reduced methane emission in rice paddy field. A sustainable agricultural production mode was formed.
基金the China University of Petroleum Foundationthe Research Institute of Safety and Environment TechnologyChina National Petroleum Corporation
文摘This study aims at determining the optimal CO2 separation technology for Chinese refineries, based on current available technologies, by the method of comprehensive evaluation. Firstly, according to the characteristics of flue gas from Chinese refineries, three feasible CO2 separation technologies are selected. These are pressure swing adsorption （PSA）, chemical absorption （CA）, and membrane absorption （MA）. Secondly, an economic assessment of these three techniques is carried out in accordance with cash flow analysis. The results show that these three techniques all have economic feasibility and the PSA technique is the best. Finally, to further optimize the three techniques, a two-level fuzzy comprehensive evaluation model is established, including economic, technological, and environmental factors. Considering all the factors, PSA is optimal for Chinese refineries, followed by CA and MA. Therefore, to reduce Chinese refineries carbon emission, it is suggested that CO2 should be captured from off-gases using PSA.
基金supported by the National Health Commission of the People’s Republic of China (formerly the Health and Family Planning Commission) of China (No. 201502004)
文摘Objective:This study evaluated the feasibility of different cervical cancer screening strategies in urban China.Methods:A Markov model was constructed to simulate a hypothetical cohort of 100,000 females aged 30-59 years in a 20-year period.Screening strategies included liquid-based cytology(LBC)every three years,human papillomavirus(HPV)DNA testing every three and five years,respectively,and a combination of HPV DNA testing and LBC(HPV+LBC)every three and five years,respectively.Model outcomes included cumulative incidence over 20 years,cumulative risk of cervical cancer,costs,life year saved(LYS),quality-adjusted life years(QALYs)and benefits.The cost-effectiveness ratios(CERs),incremental cost-effectiveness ratios(ICERs),costutility ratios(CURs),and benefit-cost ratios(BCRs)were used as outcomes in the health economic evaluation analysis.Univariate sensitivity analyses were performed to examine the stability of the results.Results:The cumulative incidence of the five screening strategies ranged from 833.02 to 1,158.07 cases per100,000 females.HPV DNA testing was most effective in reducing the cumulative risk of cervical cancer,saving life years and QALYs and gaining benefits.The CERs of HPV DNA testing every three and five years,and LBC every three years were considered to be very cost-effective if they were below China's GDP per capita.The CERs of HPV+LBC were considered to be cost-effective if they were below three times GDP per capita.The incremental cost-effectiveness analysis showed that HPV DNA testing every three and five years,LBC every three years and HPV+LBC every five years were dominant strategies.Conclusions:The findings of this study indicated that HPV DNA testing every five years or LBC every three years should be recommended in urban China.
基金Supported by a grant from The National Science and Technology Support Project in the 11th Five-year Plan (2006BAI12B07)
文摘OBJECTIVE:To analyze the cost effect of surrounding acupuncture plus electric acupuncture,cotton-sheet moxibustion,puncturing with red-hot needles,tapping plus cupping on herpes zoster.METHODS:Five hundred patients with herpes zoster were randomly divided into group A(surrounding acupuncture plus electric acupuncture),group B(cotton-sheet moxibustion),group C(puncturing with red-hot needles),group D(tapping plus cupping),and group E(Western medicine).The treatment was carried out twice a day in group E and once a day in the other four groups.The curative effect was observed on the 10th day of treatment;the cost was calculated for the five therapies,and the cost-effect ratio(C/E) and increment ratio(△ C/△ E) were analyzed.RESULTS:After the 10-day treatment,there was no statistical difference(P>0.05) in the curative effect among the five groups.Pain being alleviated one day faster than in group E amounted to a saving of RMB 21.90 yuan in group A,a saving of RMB 21.87 yuan in group B,a saving of RMB 26.00 yuan in group C,and a saving of RMB 20.23 yuan in group D.Compared with group C,the values of △ C/△ E were RMB 1.55,2.81,and 0.21 yuan in groups A,B,and D,respectively.CONCLUSIONS:The curative effect in groups A,B,C,and D was similar to that in group E,but the C/E was better than in group E.
文摘The main purpose of this study is to give evaluation of ecological services of Jilin Province, Northeast China. To take this value into decision-making and GDP accounting system is considered to be one of the economic solutions for ecological problems. The evaluation is based on the methods proposed by COSTANZA et al., and some modifications about unit value of forest and cropland system were made according to the real characters of ecosystem, climate, natural conditions etc., in Jilin Province. Total value of ecosystem services is about 554.404x10(9) yuan(RMB)/a, which is about 4.9 times of GDP of the corresponding period. The results of this study could be used as a fundamental work for the construction of ecological province, which was carried out from 2001, and could provide ecological information for decision-making. Furthermore, the necessities for the further studies on the evaluation of ecological services and natural capital were discussed.
文摘The environment impact of the coal resources mining was analyzed. The method of economic evaluation for the coal mining was established to analyze land destruction. The opportunity cost method was used to quantitatively analyze and estimate the economic loss of the land destruction by coal mining. At the same time, the dump land reclamation of the Yuanbaoshan Open Pit was taken as an example to evaluate environmental and economical benefit with the method of economic evaluation for the coal mining areas land reclamation.
基金supported by State Grid Zhejiang Electric Power Co.,Ltd.(Project of Research on interactive operation control technology and business model of 5G base station energy storage and power grid(B311JX210006)).
文摘Energy storage system is an important means to improve the flexibility and safety of traditional power system,but it has the problem of high cost and unclear value recovery path.In this paper,the typical application scenarios of energy storage system are summarized and analyzed from the perspectives of user side,power grid side and power generation side.Based on the typical application scenarios,the economic benefit assessment framework of energy storage system including value,time and efficiency indicators is proposed.Typical battery energy storage projects are selected for economic benefit calculation according to different scenarios,and key factors are selected for sensitivity analysis.Finally,the key factors affecting economic benefit of the energy storage system are analyzed.
文摘Rice straw is a rice by-product, which is currently mostly wasted in Vietnam, in particular in the Mekong delta. At present, the cost of straw gathering is increasing because of the increased use of combine harvesters. High labor cost and lack of labor makes manual collection unfeasible. Farmers therefore often just burn it, which causes pollution, increased greenhouse gas emissions and loss of opportunities to value add. An economic and environmental evaluation and technical field testing of a straw baler with 4 ha/day capacity was therefore conducted in Long An province. During the field testing data on the gathering capacity, fuel consumption, labor requirement and other cost items were collected. The test results showed that the baling cost is US$19.0 per ton of rice straw, the pay-back period of 2. 1 years and the internal rate of return of 38%. In addition to the baling cost, the transportation cost varies from US$24 for a distance of 100 km to US$32 for 150 km. The benefits of the machine are not only economical but also include the reduction of field burning.
文摘The publication of ISO 15686-5 is significant for studies related to the life-cycle costs of buildings. Among the many economic evaluation methods, the NPV method is recommended for use by this standard. This study explains the concept and method of PV, and then provides an explanation of the concept and method of NPV, and points out the limitations in the practical application of the method.
文摘China is rich in tight sandstone gas resources(“tight gas”for short).For example,the Sulige Gasfield in the Ordos Basin and the Upper Triassic Xujiahe Fm gas reservoir in the Sichuan Basin are typical tight gas reservoirs.In the past decade,tight gas reserve and production both have increased rapidly in China,but tight gas reservoirs are always managed as conventional gas reservoirs without effective fiscal,taxation and policy supports.The potential of sustainable tight gas production increase is obviously restricted.The tight gas development projects represented by the Sulige Gasfield have failed to make profit for a long period,and especially tight gas production has presented a slight decline since 2015.In this paper,a new economic evaluation method was proposed for tight gas development projects.The new method was designed to verify the key parameters(e.g.production decline rate and single-well economic service life)depending on tight gas development and production characteristics,and perform the depreciation by using the production method.Furthermore,the possibility that the operation cost may rise due to pressure-boosting production and intermittent opening of gas wells is considered.The method was used for the tight gas development project of Sulige Gasfield,showing that its profit level is much lower than the enterprise's cost level of capital.In order to support a sustainable development of tight gas industry in China,it is recommended that relevant authorities issue value-added tax(VAT)refund policy as soon as possible.It is necessary to restore the non-resident gas gate price of the provinces where tight gas is produced to the fair and reasonable level in addition to the fiscal subsidy of CNY0.24/m^(3),or offer the fiscal subsidy of CNY0.32/m^(3) directly based on the on-going gate price.With these support policies,tax income is expected to rise directly,fiscal expenditure will not increase,and gas consumption cost in China will be significantly cut down.
文摘Objective To evaluate the economy of detecting gastric cancer by electronic gastroscope in Chinese natural population of different ages and genders.Methods A Markov model was constructed for the population,including both men and women of different ages.The model cycle was one year and the simulation time was 60 years.The cost-effectiveness of electronic gastroscopy in detecting gastric cancer of general population in China was analyzed from the perspective of the whole society,and the stability of the results was verified by sensitivity analysis.Results and Conclusion For the general population,the incremental cost-effectiveness ratio(ICER)of gastric cancer screening from the age of 50 is 50143 yuan/QALY(quality-adjusted life-year),which is less than two times of per capita gross domestic product(GDP)compared with the screening from the age of 55.For men who start gastric cancer screening at the age of 50,the ICER is 38525 yuan/QALY,which is less than two times of per capita GDP,and it is economical.For women who start the screening from the age of 55,the ICER is 47814 yuan/QALY,which is less than two times of per capita GDP,so it is economical.The results of sensitivity analysis are consistent with the conclusions of basic analysis,and the results of basic analysis are stable.For the general population,it is more economical to start gastric cancer screening from the age of 50,while for men and women,it is more economical to start gastric cancer screening from the age of 50 and 55,respectively.
文摘Hydraulic fracturing is among the approaches used to optimize production from a gas condensate reservoir. A detailed economic analysis is required to evaluate the profitability and feasibility of hydraulic fracturing as an optimization option in a gas condensate reservoir operating below dewpoint. The objective of this research is to evaluate the economic benefits derivable from the use of hydraulic fracturing to improve gas and liquid recovery from a gas condensate reservoir operating below dewpoint. This research considers the use of four profit indicators to ascertain the profitability of hydraulic fracturing in a gas condensate reservoir operating below dewpoint by increasing the fracture halflength, fracture width and fracture permeability. The production data of the reservoir was obtained and the economic calculations done on excel spreadsheet and plots generated. The four profit indicators considered in the research are Net Present Value, Payout, Discounted Cash Flow Rate of Return and Profit per Dollar Invested. The economic justification was done by carrying out a comparative economic analysis from the result obtained when the reservoir of study was unfractured with that obtained when the reservoir was fractured at various fracture parameters. The economic analysis was done considering a royalty and tax rate of 18.5% and 30% respectively and a gas price of $2/MSCF and condensate price of $30/bbl. This is done so as to find out if the additional cost of hydraulic fracturing can be offset by the recovery from the reservoir when its pressure declined below dewpoint. The result obtained showed that the additional recovery due to hydraulic fracturing by increasing the fracture halflength, fracture width and fracture permeability was not enough to justify the application of hydraulic fracturing when the reservoir pressure declined below dewpoint.
文摘Taking the economic evaluation of a highway with international bank loan in Guangxi mountainous and hilly areas as an example, this paper summarizes the characteristics of economic evaluation of international bank loan highway projects, and puts forward the economic evaluation model of international bank loan highway projects, which can provide reference for other international loan highway construction projects.
文摘At this stage, China is vigorously promoting the reform of the supply-side structure to promote the transformation and upgrading of the economy. In this process, the project investment decision of the enterprise plays a very important role, which affects the development of the enterprise. It is necessary to apply the financial and economic evaluation method in a timely manner to identify the risks in the project investment decision and improve the safety of the enterprise development. Based on this, this paper analyzes the financial and economic evaluation method from three aspects of connotation, significance and classification, clarifies the analysis that should be paid attention to in the application process of this method, and explains the specific application, in order to provide reference for the follow-up research in this field.
文摘Fluoropyrimidines(FP),including 5-fluorouracil and its prodrug capecitabine,are commonly employed in treating various solid tumors.Nonetheless,their use is frequently constrained by severe toxicities in 20%-30%of patients.Pharmacogenetic testing for dihydropyrimidine dehydrogenase(DPYD)deficiency,based on DPYD polymorphisms,has notably decreased severe adverse events,improving the safety of FP therapy.A recent D'Amato et al study evaluated the prevalence of DPYD polymorphisms and their effect on FP tolerability among Italian patients with gastrointestinal cancers.Although this study provided important insights into the significance of DPYD testing,its retrospective nature,inconsistency in testing DPYD variants,and lack of consideration for socioeconomic and confounding factors showed considerable limitations.Expanding the screening to include DPYD variants,addressing confounding biases through robust statistical analyses,and implementing prospective studies are critical next steps to strengthen the clinical evidence.Furthermore,the absence of a comprehensive cost-effectiveness analysis highlights the need for further financial assessments to advocate for broader implementation.We emphasized integrating DPYD-guided dosing,pre-treatment genetic counseling,and standardized testing procedures into clinical practice to improve patient outcomes and minimize treatment-related toxicities.
