Hydrogen,as a clean and sustainable energy source,is of great significance in addressing energy crises and environmental issues.Microorganisms such as Escherichia coli(E.coli)are commonly used to produce hydrogen due ...Hydrogen,as a clean and sustainable energy source,is of great significance in addressing energy crises and environmental issues.Microorganisms such as Escherichia coli(E.coli)are commonly used to produce hydrogen due to their high efficiency,wide choice of substrates,and fast growth rate.However,the hydrogenase in E.coli can only be activated to produce hydrogen under anaerobic conditions,which greatly limits its practical application as a hydrogen producing microorganism.Herein,we report a strategy to construct E.coli@ZIF-8 micro-nano reactors(MNRs).展开更多
Chronic bacterial infections present a significant clinical challenge due to microbial persistence within host cells and the formation of biofilm structures.1 Intracellular pathogens,including Staphylococcus aureus(S....Chronic bacterial infections present a significant clinical challenge due to microbial persistence within host cells and the formation of biofilm structures.1 Intracellular pathogens,including Staphylococcus aureus(S.aureus)and Escherichia coli(E.coli),have developed immune escape mechanisms that hinder phagolysosomal killing.By shielding themselves from humoral immune factors and limiting exposure to antibiotics,these pathogens can establish long-term reservoirs and sustain recurrent infections.展开更多
基金supported by the National Natural Science Foundation of China(22205100,22375091,and 21971114)the Jiangsu Provincial Funds for Natural Science Foundation(BK20200090).
文摘Hydrogen,as a clean and sustainable energy source,is of great significance in addressing energy crises and environmental issues.Microorganisms such as Escherichia coli(E.coli)are commonly used to produce hydrogen due to their high efficiency,wide choice of substrates,and fast growth rate.However,the hydrogenase in E.coli can only be activated to produce hydrogen under anaerobic conditions,which greatly limits its practical application as a hydrogen producing microorganism.Herein,we report a strategy to construct E.coli@ZIF-8 micro-nano reactors(MNRs).
文摘Chronic bacterial infections present a significant clinical challenge due to microbial persistence within host cells and the formation of biofilm structures.1 Intracellular pathogens,including Staphylococcus aureus(S.aureus)and Escherichia coli(E.coli),have developed immune escape mechanisms that hinder phagolysosomal killing.By shielding themselves from humoral immune factors and limiting exposure to antibiotics,these pathogens can establish long-term reservoirs and sustain recurrent infections.
