期刊文献+
共找到7,600篇文章
< 1 2 250 >
每页显示 20 50 100
利用ECHO模型评价药学质控对药物治疗管理服务的影响
1
作者 刘坤 蒋欢欢 +10 位作者 李玉双 黄炎 张倩影 陈冬 谷秀林 封锦慧 王紫监 陈云飞 齐亚娟 戈艳蕾 付爱双 《中国药房》 北大核心 2025年第9期1123-1128,共6页
目的利用经济、临床、人文产出(ECHO)模型评价药学质控对冠心病患者实施标准化药物治疗管理(MTM)服务效率和产出的影响。方法收集2023年1-3月(质控实施前组,96例)和6-8月(质控实施后组,164例)接受MTM服务的冠心病患者病例资料,采用倾向... 目的利用经济、临床、人文产出(ECHO)模型评价药学质控对冠心病患者实施标准化药物治疗管理(MTM)服务效率和产出的影响。方法收集2023年1-3月(质控实施前组,96例)和6-8月(质控实施后组,164例)接受MTM服务的冠心病患者病例资料,采用倾向性评分匹配法,每组各纳入80例患者,比较匹配后两组患者药学服务的经济、临床和人文产出指标差异。结果匹配后两组患者的基线资料比较差异均无统计学意义(P>0.05)。与质控实施前组比较,质控实施后组患者的日均治疗总成本(16.26元vs.24.40元,P<0.001)、成本-效用比[23.12元/质量调整生命年(QALY)vs.32.32元/QALY,P<0.001]、一般的药品不良反应发生率(2.50%vs.10.00%,P=0.049)均显著降低,欧洲五维生存质量量表效用值(0.74±0.06 vs.0.71±0.07,P=0.003)、药物治疗相关问题减少数量(1.0个vs.0.5个,P<0.001)、用药依从性评分[(6.32±0.48)分vs.(6.10±0.37)分,P=0.001]和满意度评分[(92.56±1.52)分vs.(91.95±1.56)分,P=0.013)]均显著升高;两组患者均未发生严重的药品不良反应,新的药品不良反应发生率比较差异无统计学意义(1.25%vs.3.75%,P=0.310)。结论药学质控可提高药学服务工作质量;ECHO模型可对MTM服务效果进行量化评价,使药学服务更好计价,更能适应社会需求,值得推广。 展开更多
关键词 药物治疗管理 药学质控 echo模型 药学服务
暂未订购
An adaptive continuous threshold wavelet denoising method for LiDAR echo signal
2
作者 Dezhi Zheng Tianchi Qu +4 位作者 Chun Hu Shijia Lu Zhongxiang Li Guanyu Yang Xiaojun Yang 《Nanotechnology and Precision Engineering》 2025年第2期51-62,共12页
Atmospheric aerosols are the primary contributors to environmental pollution.As such aerosols are micro-to nanosized particles invisible to the naked eye,it is necessary to utilize LiDAR technology for their detection... Atmospheric aerosols are the primary contributors to environmental pollution.As such aerosols are micro-to nanosized particles invisible to the naked eye,it is necessary to utilize LiDAR technology for their detection.The laser radar echo signal is vulnerable to background light and electronic thermal noise.While single-photon LiDAR can effectively reduce background light interference,electronic thermal noise remains a significant challenge,especially at long distances and in environments with a low signal-to-noise ratio(SNR).However,conventional denoising methods cannot achieve satisfactory results in this case.In this paper,a novel adaptive continuous threshold wavelet denoising algorithm is proposed to filter out the noise.The algorithm features an adaptive threshold and a continuous threshold function.The adaptive threshold is dynamically adjusted according to the wavelet decomposition level,and the continuous threshold function ensures continuity with lower constant error,thus optimizing the denoising process.Simulation results show that the proposed algorithm has excellent performance in improving SNR and reducing root mean square error(RMSE)compared with other algorithms.Experimental results show that denoising of an actual LiDAR echo signal results in a 4.37 dB improvement in SNR and a 39.5%reduction in RMSE.The proposed method significantly enhances the ability of single-photon LiDAR to detect weak signals. 展开更多
关键词 Single-photon LiDAR echo signal Adaptive thresholding Wavelet transform
暂未订购
Enhanced Nowcasting Through a Novel Radar Echo Extrapolation Algorithm:Integrating Recurrent Convolutional Neural Networks with Optical Flow Methods
3
作者 Xugang LI Zhiyuan SHU +4 位作者 Shaoyu HOU Feng LV Wuyi WANG Rong MAI Haipeng ZHU 《Meteorological and Environmental Research》 2025年第3期51-56,共6页
This study proposes a novel radar echo extrapolation algorithm,OF-ConvGRU,which integrates Optical Flow(OF)and Convolutional Gated Recurrent Unit(ConvGRU)methods for improved nowcasting.Using the Standardized Radar Da... This study proposes a novel radar echo extrapolation algorithm,OF-ConvGRU,which integrates Optical Flow(OF)and Convolutional Gated Recurrent Unit(ConvGRU)methods for improved nowcasting.Using the Standardized Radar Dataset of the Guangdong-Hong Kong-Macao Greater Bay Area,the performance of OF-ConvGRU was evaluated against OF and ConvGRU methods.Threat Score(TS)and Bias Score(BIAS)were employed to assess extrapolation accuracy across various echo intensities(20-50 dBz)and weather phenomena.Results demonstrate that OF-ConvGRU significantly enhances prediction accuracy for moderate-intensity echoes(30-40 dBz),effectively combining OF s precise motion estimation with ConvGRU s nonlinear learning capabilities.However,challenges persist in low-intensity(20 dBz)and high-intensity(50 dBz)echo predictions.The study reveals distinct advantages of each method in specific contexts,highlighting the importance of multi-method approaches in operational nowcasting.OF-ConvGRU shows promise in balancing short-term accuracy with long-term stability,particularly for complex weather systems. 展开更多
关键词 Radar echo extrapolation NOWCASTING Optical flow Deep learning
在线阅读 下载PDF
A Correntropy-Based Echo State Network With Application to Time Series Prediction
4
作者 Xiufang Chen Zhenming Su +1 位作者 Long Jin Shuai Li 《IEEE/CAA Journal of Automatica Sinica》 2025年第2期425-435,共11页
As a category of recurrent neural networks,echo state networks(ESNs)have been the topic of in-depth investigations and extensive applications in a diverse array of fields,with spectacular triumphs achieved.Nevertheles... As a category of recurrent neural networks,echo state networks(ESNs)have been the topic of in-depth investigations and extensive applications in a diverse array of fields,with spectacular triumphs achieved.Nevertheless,the traditional ESN and the majority of its variants are devised in the light of the second-order statistical information of data(e.g.,variance and covariance),while more information is neglected.In the context of information theoretic learning,correntropy demonstrates the capacity to grab more information from data.Therefore,under the guidelines of the maximum correntropy criterion,this paper proposes a correntropy-based echo state network(CESN)in which the first-order and higher-order information of data is captured,promoting robustness to noise.Furthermore,an incremental learning algorithm for the CESN is presented,which has the expertise to update the CESN when new data arrives,eliminating the need to retrain the network from scratch.Finally,experiments on benchmark problems and comparisons with existing works are provided to verify the effectiveness and superiority of the proposed CESN. 展开更多
关键词 Correntropy echo state network(ESN) noise time series prediction
在线阅读 下载PDF
Iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL-IQ) for evaluation of early bone mass changes in ageing osteoporosis patients
5
作者 Yonggui Yang Fang Chen +2 位作者 Xiufen Wu Xinyu Xu Pu-Yeh Wu 《Magnetic Resonance Letters》 2025年第2期11-18,共8页
This study explored the application value of iterative decomposition of water and fatwith echo asymmetry and least-squares estimation(IDEAL-IQ)technology in the early diagnosis of ageing osteoporosis(OP).172 participa... This study explored the application value of iterative decomposition of water and fatwith echo asymmetry and least-squares estimation(IDEAL-IQ)technology in the early diagnosis of ageing osteoporosis(OP).172 participants were enrolled and underwentmagnetic resonance imaging(MRI)examinations on a 3.0T scanner.100 cases were included in the normal group(50 males and 50 females;mean age:45 years;age range:20e84 years).33 cases were included in the osteopenia group(17 males and 16 females;mean age:55 years;age range:43e83 years).39 caseswere includedintheOP group(19males and20females;meanage:58years;age range:48 e82 years).Conventional T1WI and T2WI were first obtained,followed by 3D-IDEAL-IQ-acqui-sition.Fat fraction(FF)and apparent transverse relaxation rate(R2*)resultswere automatically calculated from IDEAL-IQ-images on the console.Based on T1Wand T2W-images,300 ROIs for each participantweremanually delineated in L1-L5 vertebral bodies of five middle slices.In each age group of all normal subjects,each parameter was significantly correlated with gender.In male participants from the normal,osteopenia,and OP groups,statistical analysis revealed F values of 11319.292 and 180.130 for comparisons involving FF and R2*values,respectively(all p<0.0001).The sensitivity and specificity of FF values were 0.906 and 0.950,0.994 and 0.997,0.865 and 0.820,respectively.For R2*,they were 0.665 and 0.616,0.563 and 0.519,0.571 and 0.368,respectively.In female participants from the normal,osteopenia,and OP-groups,statis-tical analysis revealed F values of 12461.658 and 548.274 for comparisons involving FF and R2*values,respectively(all p<0.0001).The sensitivity and specificity of FF values were 0.985 and 0.991,0.996 and 0.996,0.581 and 0.678,respectively.For R2*,they were 0.698 and 0.730,0.603 and 0.665,0.622 and 0.525,respectively.Significant differences were indicated in the quanti-tative values among the three groups.FF value had good performance,while R2*value had poor performance indiscriminatingosteopenia andOP-groups.Overall,the IDEAL-IQ techniqueoffers specific reference indices that enable noninvasive and quantitative assessment of lumbar vertebrae bone metabolism,thereby providing diagnostic information for OP. 展开更多
关键词 Magnetic resonance imaging Iterative decomposition of water and fat with echo asymmetry and least-squares estimation Bone mineral density OSTEOPOROSIS Osteopenia
暂未订购
应用ECHO模型评价药物治疗管理服务在儿童支气管哮喘治疗中的效果 被引量:2
6
作者 连玉菲 邱学佳 +2 位作者 杨玉鹏 刘洪涛 董占军 《医药导报》 CAS 北大核心 2024年第10期1672-1679,共8页
目的探究药物治疗管理(MTM)服务对儿童哮喘治疗的应用效果。方法选取2022年7—12月在河北省人民医院咳喘药学门诊就诊的5~11岁哮喘患儿107例,随机分成对照组(50例)和干预组(52例)。对照组患儿首诊时给予单次吸入制剂教育服务;干预组患... 目的探究药物治疗管理(MTM)服务对儿童哮喘治疗的应用效果。方法选取2022年7—12月在河北省人民医院咳喘药学门诊就诊的5~11岁哮喘患儿107例,随机分成对照组(50例)和干预组(52例)。对照组患儿首诊时给予单次吸入制剂教育服务;干预组患儿给予全程规范化MTM服务。应用经济、临床与人文结果(ECHO)模型,分别于干预前、干预3个月及干预6个月后,统计2组患儿在经济(药物成本、成本-效用比),临床(ACT评分、吸入制剂使用正确率、哮喘发作次数)和人文(EQ-5D-5L效用值、Morisky用药依从性、患者满意度)结果中的差异,评价MTM服务在哮喘患儿中的应用效果。结果干预前2组各项评分指标差异无统计学意义;干预后干预组患儿经济结果、临床结果、人文结果3方面均优于对照组,差异有统计学意义(P<0.05)。结论药师主导的MTM服务可使哮喘患儿在经济、临床、人文多维度获益,既使哮喘患儿疾病得到长期有效控制,又提升药师药学专科服务能力。 展开更多
关键词 echo模型 儿童哮喘 效果评价 吸入制剂
暂未订购
Unraveling Mystique: Long-Delay Echoes;Anomalous Propagation of Radar Signals under the Influence of Unidentified Anomalous Phenomena
7
作者 John Tedesco Gerald Thomas Tedesco 《Open Journal of Applied Sciences》 2024年第12期3618-3648,共31页
This research study represents an ongoing research effort on Unidentified Anomalous Phenomena (UAP) with a focus on anomalous propagation of radar echo returns, mirroring established theoretical constructs of gravitat... This research study represents an ongoing research effort on Unidentified Anomalous Phenomena (UAP) with a focus on anomalous propagation of radar echo returns, mirroring established theoretical constructs of gravitational effects on light, which occur at higher frequencies and shorter wavelengths within the Electromagnetic Spectrum. These influences are also illustrated through other technologies, including Light Detection and Ranging (LIDAR) and the chromatic effects captured by hyperspectral cameras. This research addresses the complexities of interpreting unusual propagation patterns, such as Long Delay Echoes (LDE) and unexpected Field Echoes (UFE), which disrupt the anticipated propagation and echo protocols, thereby challenging our understanding and comprehension of radio transmission norms that may be influenced by a form of quantum entanglement. The paper posits a significant and largely unexamined correlation between these phenomena in the context of UAP activity, highlighting the urgent need for further research and innovative strategies in navigation technology and environmental monitoring to investigate these potential occurrences, which have remained enigmatic for nearly a century. Radar signals are vulnerable to intricate dynamics that can lead to Unusual Field Echoes (UFE), resulting in emergent anomalies, such as Multiple echo returns and LDEs. This study employed a 3-centimeter marine-based X-band radar operating in two scan geometries and a portable short-range millimeter-wave Doppler radar system. An analysis of these radar echoes over a two-year study identified signal propagation that deviated from navigational standards on Plan Position Indicators (PPI). This paper explores and investigates the potential impacts of UAP on radar transmission routes. Examining these complexities makes a case for an enhanced understanding of the interactions between established technological factors and elusive aerial phenomena. 展开更多
关键词 Radio Detection and Ranging (RADAR) Light Detection and Ranging (LIDAR) Long-Delay-echo (LDE) Millimeter-Wave (MW) RADAR Unidentified Aerial Phenomena (UAP) Anomalous Propagation (AP) Universal Field echoes (UFE) Plan Position Indicator (PPI)
在线阅读 下载PDF
A Novel On-Site-Real-Time Method for Identifying Characteristic Parameters Using Ultrasonic Echo Groups and Neural Network 被引量:1
8
作者 Shuyong Duan Jialin Zhang +2 位作者 Heng Ouyang Xu Han Guirong Liu 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第1期215-228,共14页
On-site and real-time non-destructive measurement of elastic constants for materials of a component in a in-service structure is a challenge due to structural complexities,such as ambiguous boundary,variable thickness... On-site and real-time non-destructive measurement of elastic constants for materials of a component in a in-service structure is a challenge due to structural complexities,such as ambiguous boundary,variable thickness,nonuniform material properties.This work develops for the first time a method that uses ultrasound echo groups and artificial neural network(ANN)for reliable on-site real-time identification of material parameters.The use of echo groups allows the use of lower frequencies,and hence more accommodative to structural complexity.To train the ANNs,a numerical model is established that is capable of computing the waveform of ultrasonic echo groups for any given set of material properties of a given structure.The waveform of an ultrasonic echo groups at an interest location on the surface the structure with material parameters varying in a predefined range are then computed using the numerical model.This results in a set of dataset for training the ANN model.Once the ANN is trained,the material parameters can be identified simultaneously using the actual measured echo waveform as input to the ANN.Intensive tests have been conducted both numerically and experimentally to evaluate the effectiveness and accuracy of the currently proposed method.The results show that the maximum identification error of numerical example is less than 2%,and the maximum identification error of experimental test is less than 7%.Compared with currently prevailing methods and equipment,the proposefy the density and thickness,in addition to the elastic constants.Moreover,the reliability and accuracy of inverse prediction is significantly improved.Thus,it has broad applications and enables real-time field measurements,which has not been fulfilled by any other available methods or equipment. 展开更多
关键词 Parameter identification Ultrasonic echo group High-precision modeling Artificial neural network NDT
在线阅读 下载PDF
Enhanced air-coupled impact echo technique by phase analysis of signals from multiple sensors 被引量:1
9
作者 Najjiya Almallah Nenad Gucunski 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第2期297-310,共14页
This paper presents an air-coupled impact echo(IE)technique that relies on the phase spectrum of the collected data to find the frequencies corresponding to the reflections from delaminations.The proposed technique ta... This paper presents an air-coupled impact echo(IE)technique that relies on the phase spectrum of the collected data to find the frequencies corresponding to the reflections from delaminations.The proposed technique takes advantage of the fact that the IE compression wave is not a propagating wave,but it is the 1st order symmetrical(S1)mode Lamb wave at zero group velocity(S1-ZGV).Therefore,it searches the phase spectra of the data collected by multiple sensors to locate the frequency corresponding to the lowest phase difference.As a result,the technique reduces the effect of propagating waves,including the direct acoustic wave and ambient noise.It is named the Constant Phase IE(CPIE).The performance of the CPIE is experimentally compared with the regular amplitude spectrum-based IE technique and two other multisensor IE techniques.The CPIE shows a performance advantage,especially in a noisy environment. 展开更多
关键词 nondestructive testing(NDT) nondestructive evaluation(NDE) bridge inspection bridge evaluation impact echo bridge delamination concrete bridge deck air-coupled sensing MEMS
在线阅读 下载PDF
Exploring the associations between skeletal muscle echogenicity and physical function in aging adults:A systematic review with meta-analyses
10
作者 Dustin J.Oranchuk Stephan G.Bodkin +1 位作者 Katie L.Boncella Michael O.Harris-Love 《Journal of Sport and Health Science》 SCIE CAS CSCD 2024年第6期820-840,共21页
Background:Assessment and quantification of skeletal muscle within the aging population is vital for diagnosis,treatment,and injury/disease prevention.The clinical availability of assessing muscle quality through diag... Background:Assessment and quantification of skeletal muscle within the aging population is vital for diagnosis,treatment,and injury/disease prevention.The clinical availability of assessing muscle quality through diagnostic ultrasound presents an opportunity to be utilized as a screening tool for function-limiting diseases.However,relationships between muscle echogenicity and clinical functional assessments require authoritative analysis.Thus,we aimed to(a) synthesize the literature to assess the relationships between skeletal muscle echogenicity and physical function in older adults(≥60 years),(b) perform pooled analyses of relationships between skeletal muscle echogenicity and physical function,and(c) perform sub-analyses to determine between-muscle relationships.Methods:CINAHL,Embase,MEDLINE,PubMed,and Web of Science databases were systematically searched to identify articles relating skeletal muscle echogenicity to physical function in older adults.Risk-of-bias assessments were conducted along with funnel plot examination.Meta-analyses with and without sub-analyses for individual muscles were performed utilizing Fisher's Z transformation for the most common measures of physical function.Fisher's Z was back-transformed to Pearson's r for interpretation.Results:Fifty-one articles(n=5095,female=~2759,male=~2301,72.5± 5.8 years,mean±SD(1 study did not provide sex descriptors))were extracted for review,with previously unpublished data obtained from the authors of 13 studies.The rectus femoris(n=34) and isometric knee extension strength(n=22) were the most accessed muscle and physical qualities,respectively.The relationship between quadriceps echogenicity and knee extensor strength was moderate(n=2924,r=-0.36(95% confidence interval:-0.38 to-0.32),p <0.001),with all other meta-analyses(grip strength,walking speed,sit-to-stand,timed up-and-go) resulting in slightly weaker correlations(r:-0.34 to-0.23,all p <0.001).Sub-analyses determined minimal differences in predictive ability between muscle groups,although combining muscles(e.g.,rectus femoris+vastus lateralis) often re sulted in stronger correlations with maximal strength.Conclusion:While correlations are modest,the affordable,portable,and noninvasive ultrasonic assessment of muscle quality is a consistent predictor of physical function in older adults.Minimal between-muscle differences suggest that echogenicity estimates of muscle quality are systemic.Therefore,practitioners may be able to scan a single muscle to estimate full-body skeletal muscle quality/composition,while researchers should consider combining multiple muscles to strengthen the model. 展开更多
关键词 CORRELATIONS echo intensity ELDERLY Intramuscular fat Strength
暂未订购
Research on Sleeve Grouting Density Detection Based on the Impact Echo Method
11
作者 Pu Zhang Yingjun Li +5 位作者 Xinyu Zhu Shizhan Xu Pinwu Guan Wei Liu Yanwei Guo Haibo Wang 《Structural Durability & Health Monitoring》 EI 2024年第2期143-159,共17页
Grouting defects are an inherent challenge in construction practices,exerting a considerable impact on the operational structural integrity of connections.This investigation employed the impact-echo technique for the ... Grouting defects are an inherent challenge in construction practices,exerting a considerable impact on the operational structural integrity of connections.This investigation employed the impact-echo technique for the detection of grouting anomalies within connections,enhancing its precision through the integration of wavelet packet energy principles for damage identification purposes.A series of grouting completeness assessments were meticulously conducted,taking into account variables such as the divergent material properties of the sleeves and the configuration of adjacent reinforcement.The findings revealed that:(i)the energy distribution for the highstrength concrete cohort predominantly occupied the frequency bands 42,44,45,and 47,whereas for other groups,it was concentrated within the 37 to 40 frequency band;(ii)the delineation of empty sleeves was effectively discernible by examining the wavelet packet energy ratios across the spectrum of frequencies,albeit distinguishing between sleeves with 50%and full grouting density proved challenging;and(iii)the wavelet packet energy analysis yielded variable detection outcomes contingent on the material attributes of the sleeves,demonstrating heightened sensitivity when applied to ultrahigh-performance concrete matrices and GFRP-reinforced steel bars. 展开更多
关键词 Prefabricated building steel grouting sleeve impact echo method wavelet packet energy grouted defect
在线阅读 下载PDF
Relationship of inflammatory indices with left atrial appendage thrombus or spontaneous echo contrast in patients with atrial fibrillation
12
作者 Zhao Wang Bin-Hao Wang +3 位作者 Xiao-Lei Yang Yun-Long Xia Sheng-Min Zhang Ying Che 《World Journal of Clinical Cases》 SCIE 2024年第21期4550-4557,共8页
BACKGROUND Inflammatory indices derived from complete blood tests have been reported to be associated with poor outcomes in patients with atrial fibrillation(AF).The data about the relationship between inflammatory in... BACKGROUND Inflammatory indices derived from complete blood tests have been reported to be associated with poor outcomes in patients with atrial fibrillation(AF).The data about the relationship between inflammatory indices and left atrial appendage thrombus(LAAT)or dense spontaneous echo contrast(SEC)are limited.AIM To explore the value of inflammatory indices for predicting the presence of LAAT or dense SEC in nonvalvular AF patients.METHODS A total of 406 patients with nonvalvular AF who underwent transesophageal echocardiography were included and divided into two groups based on the presence(study group)or absence(control group)of LAAT or dense SEC.Inflammatory indices,including the neutrophil-to-lymphocyte ratio(NLR),platelet–tolymphocyte ratio(PLR),and lymphocyte-to-monocyte ratio(LMR),were calculated from complete blood analysis.The associations of inflammatory indices RESULTS LAAT and dense SEC were detected in 11(2.7%)and 42(10.3%)patients,respectively.The PLR only showed an association with LAAT/dense SEC in the univariate model.Elevated NLR(odds ratio[OR]=1.48,95%confidence interval[CI]:1.11-1.98,P=0.007)and reduced LMR(OR=0.59,95%CI:0.41-0.83,P=0.003)were found to be independent risk factors for the presence of LAAT/dense SEC.The areas under the NLR and LMR curves for predicting LAAT/dense SEC were 0.73(95%CI:0.66-0.80,P<0.001)and 0.73(95%CI:0.65-0.81,P<0.001),respectively,while the cutoff values were 2.8(sensitivity:69.8%;specificity:64.0%)and 2.4(sensitivity:71.7%;specificity:60.6%),respectively.CONCLUSION Increased NLR and decreased LMR may predict LAAT/dense SEC in patients with nonvalvular AF. 展开更多
关键词 Nonvalvular atrial fibrillation Left atrial appendage thrombus Spontaneous echo contrast Neutrophil–lymphocyte ratio Lymphocyte–monocyte ratio
暂未订购
Characteristics of Bow Echoes During 2011-2020 in Western South China(Guangxi)
13
作者 QI Li-yan CHEN Yun +1 位作者 YE Long-bin NONG Meng-song 《Journal of Tropical Meteorology》 2024年第4期428-443,共16页
Based on previously released data,this paper first presented the criteria for recognizing bow echoes and divided their life cycle into three stages:the development stage,the mature stage,and the attenuation stage.Base... Based on previously released data,this paper first presented the criteria for recognizing bow echoes and divided their life cycle into three stages:the development stage,the mature stage,and the attenuation stage.Based on Doppler weather radar data during 2011-2020,43 bow echo events(including 54 individual bow echoes)in western South China were identified.The spatial and temporal distributions,formation and dissipation modes of these bow echoes,and the severe weather they caused were statistically analyzed.The results show that:(1)The bow echo events were unevenly distributed year-to-year,but all occurred from March to July,with the highest in April and May and the lowest in July.The period from night to early morning was found to be the main period for bow echo generation and intensification.(2)A banded area from Hechi City on the southeastern edge of the Yunnan-Guizhou Plateau to Wuzhou City in southeast Guangxi was identified as a high-incidence area of bow echoes.The length of bow echoes was correlated with their life cycle.(3)The origins of the bow echoes could be divided into five locations,most of which were in the eastern Yunnan-Guizhou Plateau.After entering western South China,their moving paths were categorized into three types,among which most bow echoes moved southeastward,generally because of the effect of cold air.Specifically,bow echoes generally moved eastward when cold air was weak or in the warm zone.Meanwhile,the fewest bow echoes moved northeastward.(4)Four modes of bow echo formation were identified:linearly organized,broken areal,linearly merging,and broken line.Dissipation could also be classified into four types.(5)The probability of convective weather generated by a bow echo was largest in the mature stage. 展开更多
关键词 bow echo spatial and temporal distribution severe convection
在线阅读 下载PDF
2003年美国ECHO病毒9和30相关无菌性脑膜炎暴发及肠道病毒监测的初步报告 被引量:1
14
作者 屠宇平 杨小平 《疾病监测》 CAS 2004年第1期35-36,共2页
关键词 2003年 美国 echo病毒9 暴发 肠道病毒 监测 无菌性脑膜炎 echo病毒30
暂未订购
福建省2011年病毒性脑炎暴发病原Echo30分子流行病学分析 被引量:22
15
作者 杨秀惠 严延生 +6 位作者 翁育伟 何爱华 张红榕 陈炜 许江阳 林其财 周勇 《中国人兽共患病学报》 CAS CSCD 北大核心 2012年第3期265-269,共5页
目的了解福建省2011年病毒性脑炎暴发的病原特点及福建省近10年Echo30分子流行病学特征。方法应用细胞培养法获得病毒株,微量血清中和试验或RT-PCR序列分析鉴定Echo30血清型,提取病毒RNA核酸,逆转录为cD-NA,分段扩增VP1基因序列全长,测... 目的了解福建省2011年病毒性脑炎暴发的病原特点及福建省近10年Echo30分子流行病学特征。方法应用细胞培养法获得病毒株,微量血清中和试验或RT-PCR序列分析鉴定Echo30血清型,提取病毒RNA核酸,逆转录为cD-NA,分段扩增VP1基因序列全长,测定并分析扩增产物的序列。结果 2011年4月1日-6月2日,从福建省4个县(市)区病毒性脑炎病例标本中分离的病毒经鉴定均为Echo30;VP1基因序列分析显示,泉州市安溪和德化两地流行株高度同源(核苷酸与氨基酸序列同源性分别为99.0%和99.6%),同福安和厦门流行株(核苷酸与氨基酸序列同源性分别为98.5%和100%)核苷酸差异约9%,3个位点氨基酸出现了变异。近10年福建省Echo30分子流行病学分析显示,2011年泉州流行株并非由2005年当地流行株进化而来,而与2008年河南省分离株(HQ625646-Henan/04/2008)同源性最高;近10年福建省Echo30存在多基因型、多谱系的同时传播,并在2006年发现了两株第III新基因型病毒。结论造成2011年福建省病毒性脑炎暴发的病原为Echo30,且至少存在两条不同传播链病毒同时流行。Echo30福建株呈多基因型、多谱系分布流行特点。 展开更多
关键词 病毒性脑炎 echo30 VP1基因 分子流行病学
暂未订购
连云港市一起ECHO_(30)病毒性脑膜炎爆发流行病学调查 被引量:11
16
作者 朱磷扬 张廷禄 +4 位作者 朱凤东 许雷 孙波 潘红星 赵玉良 《疾病监测》 CAS 2007年第6期384-387,共4页
目的分析2006年江苏省连云港市病毒性脑膜炎爆发的流行特征、影响因素和病因。方法采用统一的流行病学调查表对病例进行调查,收集2004年以来全市各县区病毒性脑膜炎住院病例资料,采用1:2配比病例对照研究的方法分析流行因素;24份脑脊液... 目的分析2006年江苏省连云港市病毒性脑膜炎爆发的流行特征、影响因素和病因。方法采用统一的流行病学调查表对病例进行调查,收集2004年以来全市各县区病毒性脑膜炎住院病例资料,采用1:2配比病例对照研究的方法分析流行因素;24份脑脊液标本送江苏省疾病控制中心检测,并进行病毒分离。结果2004-2005年全市各县区病毒性脑膜炎病例呈现散发状态;2006年1~7月份共查出病例数为968例,从6月份起出现疫情上升,1县2区出现爆发,7月份达高峰,爆发病例为473例,占全市总病例数的48.86%;主要累及15岁以下儿童,占94.44%;男性多于女性,男女比为2.65:1;主要临床表现为发热、头痛、呕吐、脑膜刺激征阳性、脑脊液有核细胞增多。饭前洗手与多吃瓜果为保护因素,说明该病与不良卫生习惯有关系。23份脑脊液经PCR检测,16份ECHO_(30)肠道病毒阳性。结论2006年夏季江苏省连云港市病毒性脑膜炎出现一次爆发并波及1县2区,致病病原体为埃可30型肠道病毒(Echovirus 30,ECHO_(30))肠道病毒,不良卫生习惯可能是导致该病发生流行的危险因素。 展开更多
关键词 echo30 脑膜炎 爆发 流行病学调查
暂未订购
肠道病毒ECHO25河南分离株基因特征分析 被引量:4
17
作者 晁灵 黄学勇 +1 位作者 李幸乐 许汴利 《病毒学报》 CAS CSCD 北大核心 2010年第6期443-446,共4页
首次对ECHO25病毒进行分子生物学分析,阐明ECHO25(Entric Cytopathic Human Orphanviruses Type25)病毒河南分离株的分子生物学特征及其与世界其它分离株的基因关系。逆转录-聚合酶链反应(RT-PCR)扩增出VP1蛋白编码基因并进行序列测定,... 首次对ECHO25病毒进行分子生物学分析,阐明ECHO25(Entric Cytopathic Human Orphanviruses Type25)病毒河南分离株的分子生物学特征及其与世界其它分离株的基因关系。逆转录-聚合酶链反应(RT-PCR)扩增出VP1蛋白编码基因并进行序列测定,将所测4株ECHO25病毒的VP1序列与GenBank上已发表的ECH-O25病毒VP1区进行同源性比较及遗传进化分析发现:河南省4株ECHO25与标准株JV-4核苷酸同源性为79.2%~80.1%,氨基酸同源性为89.0%~92.4%;河南省4株ECHO25核苷酸同源性为93.0%~99.0%,氨基酸同源性为92.4%~97.5%;HN-01分离株与HN-26分离株高度同源,其核苷酸同源性达99.0%;河南省4株ECHO25同属B1基因亚型。 展开更多
关键词 echo25 基因 序列分析 系统发生树
原文传递
急性弛缓性麻痹病例中ECHO11病毒的基因特征分析 被引量:4
18
作者 刘桂艳 许文波 +5 位作者 纪峰 张勇 王海岩 李岩 严冬梅 徐爱强 《病毒学报》 CAS CSCD 北大核心 2006年第1期22-30,共9页
该文首次分析了我国ECHO11病毒的分子流行病学资料。1999~2004年,ECHO11病毒是山东省急性弛缓性麻痹(AFP)病例中分离到的优势毒株,2003年从山东省482例AFP病例中共分离到11株ECHO11病毒,其中相关的10例病例分布跨越山东省大部分... 该文首次分析了我国ECHO11病毒的分子流行病学资料。1999~2004年,ECHO11病毒是山东省急性弛缓性麻痹(AFP)病例中分离到的优势毒株,2003年从山东省482例AFP病例中共分离到11株ECHO11病毒,其中相关的10例病例分布跨越山东省大部分地区,但发病日期集中在7月和12月。该研究试图通过对VP1编码基因全序列的测定和分析,为探讨ECHO11病毒与AFP之间的病因关系提供线索。分子流行病学研究提示,11株ECHO11毒株都位于同一传播链,核苷酸同源性为97.2%~100%,氨基酸同源性为99.6%~100%,其中7月和12月的分离株之间相层8~9个核苷酸,氨基酸序列一致。这说明山东省2003年7月和12月分别发生了ECHO11病毒流行,但这些毒株与AFP的病因关系尚需进一步研究。11株病毒组成了A基因型中的一个新亚型,在进化树上单独呈密切相关的一簇,与同基因型内的其它亚型的核苷酸同源性为82.2%~84.7%,氨基酸同源性为94.8%~97.6%. 展开更多
关键词 急性弛缓性麻痹病例 echo11病毒 基因特征
暂未订购
ECHO 19引起龙岩市儿童病毒性脑炎的流行病学调查 被引量:11
19
作者 陈前进 俞新莲 +5 位作者 张月花 杨秀惠 严延生 黄开华 吴水新 邓小如 《海峡预防医学杂志》 CAS 2005年第4期14-16,共3页
[目的]探讨龙岩市2004年儿童病毒性脑炎流行的病因、流行规律及特征.[方法]对142例病毒性脑炎病例进行流行病学调查,对其中30例的脑脊液标本进行病毒分离和型别鉴定.[结果]142例患者分布在我市的6个县(市、区),其中新罗区占(66.2%),另... [目的]探讨龙岩市2004年儿童病毒性脑炎流行的病因、流行规律及特征.[方法]对142例病毒性脑炎病例进行流行病学调查,对其中30例的脑脊液标本进行病毒分离和型别鉴定.[结果]142例患者分布在我市的6个县(市、区),其中新罗区占(66.2%),另有广东省大埔县2例;年龄以5~12岁为多;男性68.3%,女性31.7%;5~6月为发病高峰.临床主要表现为突然发病、发热(92.4%)、头痛(83.1%)、呕吐(68.6%)等;脑电图以轻中度异常为主;67.8%血常规正常;脑脊液常规87.5%颅内压力增高,56.8%细胞数增加.疗程10天左右.从30份脑脊液中检出16株ECHO 19病毒.[结论]流行病学调查及实验室病原检测确认,龙岩市儿童病毒性脑炎病原为ECHO 19. 展开更多
关键词 病毒性脑炎 echo19 儿童 流行病学调查 脑脊液
暂未订购
2011~2014年中国福建龙岩市Echo 30型病毒分子流行病学特征分析 被引量:2
20
作者 陈前进 曹春远 +6 位作者 张彦锋 杨秀惠 吴水新 何云 廖亦红 何春荣 罗招福 《病毒学报》 CAS CSCD 北大核心 2016年第6期727-732,共6页
了解中国福建省龙岩市2011-2014年病毒性脑炎散发病例中Echo 30分子流行病学特征。收集病毒性脑炎或中枢神经系统感染脑脊液标本,细胞培养分离病毒,RT-PCR扩增VP1基因序列全长以鉴定Echo 30血清型及遗传特征分析。2011-2014年共从608例... 了解中国福建省龙岩市2011-2014年病毒性脑炎散发病例中Echo 30分子流行病学特征。收集病毒性脑炎或中枢神经系统感染脑脊液标本,细胞培养分离病毒,RT-PCR扩增VP1基因序列全长以鉴定Echo 30血清型及遗传特征分析。2011-2014年共从608例监测病例中分离到168株肠道病毒,其中60株为Echo 30;60例Echo 30相关病例分析显示,Echo 30流行高峰为6-8月;波及年龄范围广,以小于10岁高发(65%);临床症状以发热、头痛和呕吐为主,脑脊液清,细胞和蛋白含量检测多增加。VP1区分析显示,2011-2014年龙岩流行株均属于h基因型,但有两个传播链共同循环;与2011年导致福建省病毒性脑炎暴发毒株高度同源,但2014年龙岩株均在VP1蛋白I 120V出现新氨基酸变异。福建省2011年暴发流行株仍流行于龙岩市,且两个传播链病毒仍共同循环,但2014年病毒株出现了新的变异,持续监测将有利于早期发现病毒变异积累和评估疾病流行的风险。 展开更多
关键词 echo 30型病毒 病毒性脑炎 VP1 分子流行病学
原文传递
上一页 1 2 250 下一页 到第
使用帮助 返回顶部