The gear transmission system directly affects the operational performance of high-speed trains(HST).However,current research on gear transmission systems of HST often overlooks the effects of gear eccentricity and run...The gear transmission system directly affects the operational performance of high-speed trains(HST).However,current research on gear transmission systems of HST often overlooks the effects of gear eccentricity and running resistance,and the dynamic models of gear transmission system are not sufficiently comprehensive.This paper aims to establish an electromechanical coupling dynamic model of HST traction transmission system and study its electromechanical coupling vibration characteristics,in which the internal excitation factors such as gear eccentricity,time-varying meshing stiffness,backlash,meshing error,and external excitation factors such as electromagnetic torque and running resistance are stressed.The research results indicate that gear eccentricity and running resistance have a significant impact on the stability of the system,and gear eccentricity leads to intensified system vibration and decreased anti-interference ability.In addition,the characteristic frequency of gear eccentricity can be extracted from mechanical signals and current signals as a preliminary basis for eccentricity detection,and electrical signals can also be used to monitor changes in train running resistance in real time.The results of this study provide some useful insights into designing dynamic performance parameters for HST transmission systems and monitoring train operational states.展开更多
Impairments on body function,activities of daily living(ADL)and cognition are common after stroke.Eccentric resistance training(ERT)may be implemented to improve them.The primary objectives were to evaluate whether ER...Impairments on body function,activities of daily living(ADL)and cognition are common after stroke.Eccentric resistance training(ERT)may be implemented to improve them.The primary objectives were to evaluate whether ERT improves body function,ADL and cognition after stroke.The secondary objectives were to evaluate whether ERT improves strength,gait,quality of life,and self-perceived health.Seven electronic databases were searched:Cochrane Central Register of Controlled Trials,Cochrane Stroke Group Trials Register,PubMed,Epistemonikos,Embase,SPORTDiscus,and WHO International Clinical Trials Registry Platform.Last search was run in December 2023,including studies since 2012.Selection criteria were studies with stroke participants of both sexes,aged 18 or more,with an intervention based on ERT.Accepted languages were English,Spanish or French.First search was done in pairs.Authors removed duplicate studies and those which did not meet inclusion criteria through title and abstracts.Finally,all authors,independently,screened the final search results and extracted data.Of 68 records identified,15 were eligible and 6 were finally included(with moderate risk of bias),analyzing 159 participants.Body function(4 interventions,n=84),gait(4 interventions,n=115)and strength(3 interventions,n?78)showed significantly better results when ERT was performed.Meta-analysis could not be done because of the few studies and their heterogeneity.This review provided low-moderate quality evidence suggesting that ERT might be effective at improving body function,strength,and gait after stroke.Besides,no harm was documented,and it was well-accepted.展开更多
In view of the time-consuming and unreliable deficiencies of the cross-axis work piece in the clamping process,combined with the working characteristics of the eccentric mechanism,a simple and fast eccentric locking m...In view of the time-consuming and unreliable deficiencies of the cross-axis work piece in the clamping process,combined with the working characteristics of the eccentric mechanism,a simple and fast eccentric locking mechanism is designed.The push rod iquickly driven by the combined action of the handle and the drum,so that the cross shaft work piece can be quickly locked in the axial direction.The eccentric locking mechanism not only has simple operation and convenient maintenance,but also has the characteristics of low manufacturing cost and high life,and has certain reference value for future special fixture design.展开更多
Cardiovascular disease is the leading cause of human mortality,and calcified tissue blocking blood vessels is the main cause of major adverse cardiovascular events(MACE).Rotational Atherectomy(RA)is a minimally invasi...Cardiovascular disease is the leading cause of human mortality,and calcified tissue blocking blood vessels is the main cause of major adverse cardiovascular events(MACE).Rotational Atherectomy(RA)is a minimally invasive catheterbased treatment method that involves high-speed cutting of calcified tissue using miniature tools for removal.However,the cutting forces,heat,and debris can induce tissue damage and give rise to serious surgical complications.To enhance the effectiveness and efficiency of RA,a novel eccentric rotational cutting tool,with one side comprising axial and circumferential staggered micro-blades,was designed and fabricated in this study.In addition,a series of experiments were conducted to analyze their performance across five dimensions:tool kinematics,force,temperature,debris,and surface morphology of the specimens.Experimental results show that the force,temperature and debris size of the novel tool were well inhibited at the highest rotational speed.For the tool of standard clinical size(diameter 1.25 mm),the maximum force is 0.75 N,with a maximum temperature rise in the operation area of 1.09℃.Debris distribution followed a normal distribution pattern,with 90%of debris measuring smaller than 9.12μm.All tool metrics met clinical safety requirements,indicating its superior performance.This study provides a new idea for the design of calcified tissue removal tools,and contributes positively to the advancement of RA.展开更多
Background Serial sarcomere number(SSN)critically influences muscle function and is hypothesized to protect against injury.While most evidence for SSN addition comes from non-human animal studies,eccentric exercise is...Background Serial sarcomere number(SSN)critically influences muscle function and is hypothesized to protect against injury.While most evidence for SSN addition comes from non-human animal studies,eccentric exercise is often proposed as a key stimulus due to its association with increased fascicle length in humans.However,the most efficient exercise stimuli and the effectiveness of eccentric training in increasing SSN remain unclear.The objective of this study was to provide a detailed historical overview of research exploring the mechanical factors regulating muscle/fiber length and its relationship with function,and to explore more recent evidence that eccentric muscle contractions might be an important stimulus for SSN regulation using a meta-analytic approach.Methods An extensive literature search with snowballing was conducted to build the historical review.A systematic review with random-effect meta analyses was performed to compare proposed types of fiber-lengthening exercises to control conditions.Results The historical review demonstrated that the application of forces at long fiber lengths,but not specifically the use of greater excursions,plays an important role in increasing SSN.Animal data showed changes in SSN exceeding 20%over several weeks with varied forms of activities.Nonetheless,the meta-analysis revealed a lack of effect of eccentric resistance training in animal models(Δ=1%;Cohen’s d=0.19(95%confidence interval:–0.29 to 0.67),p=0.449).Conclusion High active or passive muscle forces applied at long fiber lengths appear to be the key stimuli triggering sarcomerogenesis.Eccentric exercise does not seem to be a key promoter of SSN.Too few studies exist to draw conclusions as to the effect of eccentric exercise on SSN in humans.Understanding the mechanical triggers and physiological mechanisms involved in serial sarcomere addition could help in the development of exercise(and other)interventions to optimize muscle function and reduce injury risk.展开更多
Sarcomerogenesis,the addition of serial sarcomeres in skeletal muscle myofibrils and fibres,is a natural occurrence during growth and maturation of animals,including humans.However,the detailed mechanisms that allow f...Sarcomerogenesis,the addition of serial sarcomeres in skeletal muscle myofibrils and fibres,is a natural occurrence during growth and maturation of animals,including humans.However,the detailed mechanisms that allow for sarcomerogenesis are not fully understood.In some diseases,such as cerebral palsy in children,sarcomerogenesis appears to be inhibited or at least reduced,1,2 often causing severe restrictions in muscle and joint function.展开更多
The first in vivo measurements of serial sarcomere number in human muscles before and after eccentric strength training have just been published and the results will interest anyone involved with sport or health:Train...The first in vivo measurements of serial sarcomere number in human muscles before and after eccentric strength training have just been published and the results will interest anyone involved with sport or health:Training the hamstrings 3 times per week for 9 weeks with the Nordic hamstring exercise was found to increase the number of sarcomeres in series in the biceps femoris long head(BFlh)by≥25%.1 In this commentary,we highlight an additional,paradoxical finding,which was not discussed by the authors;namely that the substantial serial sarcomere addition must have been accompanied by a subtraction of sarcomeres in parallel to match the relatively small increase in muscle volume after training.展开更多
Induction motors （IMs） are commonly used in various industrial applications. To improve energy con- sumption efficiency, a reliable IM health condition moni- toring system is very useful to detect IM fault at its ea...Induction motors （IMs） are commonly used in various industrial applications. To improve energy con- sumption efficiency, a reliable IM health condition moni- toring system is very useful to detect IM fault at its earliest stage to prevent operation degradation, and malfunction of IMs. An intelligent harmonic synthesis technique is pro- posed in this work to conduct incipient air-gap eccentricity fault detection in IMs. The fault harmonic series are syn- thesized to enhance fault features. Fault related local spectra are processed to derive fault indicators for IM air- gap eccentricity diagnosis. The effectiveness of the pro- posed harmonic synthesis technique is examined experi- mentally by IMs with static air-gap eccentricity and dynamic air-gap eccentricity states under different load conditions. Test results show that the developed harmonic synthesis technique can extract fault features effectively for initial IM air-gap eccentricity fault detection.展开更多
In gas injection refining processes, a great amount of gas is injected into molten metal in short time, so that very large bubbles are inevitably formed. Wide dispersion of small bubbles in the bath is indispensable f...In gas injection refining processes, a great amount of gas is injected into molten metal in short time, so that very large bubbles are inevitably formed. Wide dispersion of small bubbles in the bath is indispensable for high refining efficiency. Eccentric mechanical stirring with unidirectional impeller rotation was tested using a water model for pursuing better bubble disintegration and dispersion. Absorption rate are used to research on the influence law of the bubble dispersion and disintegration and gas-liquid absorption by the influence of, rotation mode, rotation speed and gas flow rate. Compared to the experimental results of absorption rate under eccentric stirring and centric stirring ,provide the scientific experimental and theoretical guidance for high-temperature experiment of hot metal desulfurization .According to experimental and theoretical analysis, this paper has studied various factors effecting on gas absorption process and volumetric mass transfer coefficient using the system of CO2-NaOH-H2O.The results show that:the volumetric mass transfer coefficient and absorption efficiency of CO2 can be increased under eccentric stirring mode, Because bubble disperse quickly with eccentric mechanical stirring, which results in promoting complete reaction between CO2 and NaOH, and improving the mass transfer coefficient and absorption. Volumetric mass transfer coefficient and efficiency of CO2 increase with the increasing rotation speed under the condition of eccentric stirring .But volumetric mass transfer coefficient and efficiency of CO2 decrease with the increasing rotation speed under the condition of centric stirring.展开更多
A novel weft insertion mechanism named eccentric conjugate non-circular gear & crank-rocker & gears train weft insertion mechanism was proposed in order to better meet the requirements of rapier loom's wef...A novel weft insertion mechanism named eccentric conjugate non-circular gear & crank-rocker & gears train weft insertion mechanism was proposed in order to better meet the requirements of rapier loom's weft insertion mechanism as well as reduce the manufacturing difficulty. Meanwhile, based on the working principle of this mechanism, kinematical mathematic models of this mechanism were established and an aided analysis and simulation software was compiled. The influences of eccentricity ratio, deformation coefficient, and other important parameters on the kinematics characteristics of this mechanism were analyzed by using the software. A group of preferable parameters which could meet the requirements of weft insertion technology were obtained by means of human-computer interactive optimization method. The maximum velocity, maximum acceleration, and variation of acceleration of this mechanism are smaller than those of the conjugate cam weft insertion mechanism applied on TT96 rapier loom under the conditions of the same unilateral total stroke of rapier head and the same rotary speed of loom spindle; meanwhile the other demands of weaving technology can be met by this novel weft insertion mechanism.展开更多
A new concept for forming eccentric shafts on the basis of the cross-wedge rolling （CWR） process was presented. This concept was based on the application of special guides, which, by acting on a billet, lead to its ...A new concept for forming eccentric shafts on the basis of the cross-wedge rolling （CWR） process was presented. This concept was based on the application of special guides, which, by acting on a billet, lead to its controlled movement in the vertical direction. This movement made possible eccentric cutting of tools into the billet. FEM calculations and experimental rolling tests clearly confirmed the effectiveness of the proposed forming method.展开更多
With the technical development of new warhead designs and improvised explosive device protection,irregular casing filled with explosive has been paid more attention recently. In this paper, we studied the fragmentatio...With the technical development of new warhead designs and improvised explosive device protection,irregular casing filled with explosive has been paid more attention recently. In this paper, we studied the fragmentation of a type of D-shaped casing, which is a common asymmetric casing in the field of warhead design. Based on the radiograph technique, static explosive experiments were conducted with D-shaped casings under four different eccentric initiation ratios to explore their fragmentation. A numerical model was then established to simulate the dynamic response of D-shaped casing filled with explosive. The results of numerical simulation were found to agree well with the experimental data.According to the results of numerical simulation and experimental data, the dynamic responses of Dshaped casing were analyzed. The results of the current work pave way for the innovative design of new warhead and for further studying the dynamic response of asymmetric casing.展开更多
Roll eccentricity is an important factor causing thickness variations during hot strip rolling and might define the limit of strip thickness control accuracy. An improved multi-resolution wavelet transform algorithm w...Roll eccentricity is an important factor causing thickness variations during hot strip rolling and might define the limit of strip thickness control accuracy. An improved multi-resolution wavelet transform algorithm was proposed to compensate for the roll eccentricity. The wavelet transform method had good localization characteristics in both the time and frequency domains for signal analysis; however, the wavelet method had a frequency-aliasing problem owing to the less than ideal cut-off frequency characteristics of wavelets. This made its component reconstruction of an inaccurate signal. To eliminate inherent frequency aliases in the wavelet transform, fast Fourier transform （FFT） and inverse fast Fourier transform （IFFT） were combined with the Mallat algorithm. This synthesis was described in detail. Then, the roll eccentricity component was extracted from rolling force signal. An automatic gauge control （AGC） system added with a multi-resolution wavelet analyzer was designed. Experimental results showed that the anti-aliasing method could greatly restrain the inverse effect of eccentricity and the thickness control accuracy was improved from ±40 μm to ±15 μm.展开更多
Neuromuscular activity is suppressed during maximal eccentric(ECC)muscle contraction in untrained subjects owing to attenuated levels of central activation and reduced spinal motor neuron(MN)excitability indicated by ...Neuromuscular activity is suppressed during maximal eccentric(ECC)muscle contraction in untrained subjects owing to attenuated levels of central activation and reduced spinal motor neuron(MN)excitability indicated by reduced electromyography signal amplitude,diminished evoked H-reflex responses,increased autogenic MN inhibition,and decreased excitability in descending corticospinal motor pathways.Maximum ECC muscle force recorded during maximal voluntary contraction can be increased by superimposed electrical muscle stimulation only in untrained individuals and not in trained strength athletes,indicating that the suppression in MN activation is modifiable by resistance training.In support of this notion,maximum ECC muscle strength can be increased by use of heavy-load resistance training owing to a removed or diminished suppression in neuromuscular activity.Prolonged(weeks to months)of heavy-load resistance training results in increased H-reflex and V-wave responses during maximal ECC muscle actions along with marked gains in maximal ECC muscle strength,indicating increased excitability of spinal MNs,decreased presynaptic and/or postsynaptic MN inhibition,and elevated descending motor drive.Notably,the use of supramaximal ECC resistance training can lead to selectively elevated V-wave responses during maximal ECC contraction,demonstrating that adaptive changes in spinal circuitry function and/or gains in descending motor drive can be achieved during maximal ECC contraction in response to heavy-load resistance training.展开更多
The forced lengthening of an activated skeletal muscle has been termed an eccentric contraction(EC).This review highlights the mechanically unique nature of the EC and focuses on the specific disruption of proteins wi...The forced lengthening of an activated skeletal muscle has been termed an eccentric contraction(EC).This review highlights the mechanically unique nature of the EC and focuses on the specific disruption of proteins within the cell known as cytoskeletal proteins.The major intermediate filament cytoskeletal protein,desmin,has been the focus of work in this area because changes to desmin occur within minutes of ECs and because desmin has been shown to play both a mechanical and biologic role in a muscle's response to EC.It is hoped that these types of studies will assist in decreasing the incidence of muscle injury in athletes and facilitating the development of new therapies to treat muscle injuries.展开更多
Background:The isometric steady-state following active lengthening is associated with greater torque production and lower activation,as measured by electromyographic activity(EMG),in comparison with a purely isometric...Background:The isometric steady-state following active lengthening is associated with greater torque production and lower activation,as measured by electromyographic activity(EMG),in comparison with a purely isometric contraction(ISO)at the same joint angle.This phenomenon is termed residual force enhancement(RFE).While there has been a great deal of research investigating the basic mechanisms of RFE,little work has been performed to understand the everyday relevance of RFE.The purpose of this study was to investigate whether neuromuscular control strategies differ between ISO and RFE by measuring torque steadiness of the human ankle plantar flexors.Methods:Following ISO maximal voluntary contractions in 12 males(25±4 years),an active lengthening contraction was performed at 15°/s over a 30°ankle excursion,ending at the same joint angle as ISO(5°dorsiflexion;RFE).Surface EMG of the tibialis anterior and soleus muscles was recorded during all tasks.Torque steadiness was determined as the standard deviation(SD)and coefficient of variation(CV)of the torque trace in the ISO and RFE condition during activation-matching(20%and 60%integrated EMG)and torque-matching(20%and 60%maximal voluntary contraction)experiments.Two-tailed,paired t tests were used,within subjects,to determine the presence of RFE/activation reduction(AR)and whether there was a difference in torque steadiness between ISO and RFE conditions.Results:During the maximal and submaximal conditions,there was 5%-9%RFE with a 9%-11%AR(p<0.05),respectively,with no difference in antagonist coactivation between RFE and ISO(p>0.05).There were no differences in SD and CV of the torque trace for the 20%and60%activation-matching or the 60%and maximal torque-matching trials in either the RFE or ISO condition(p>0.05).During the 20%torquematching trial,there were～37%higher values for SD and CV in the RFE as compared with the ISO condition(p<0.05).A significant moderate-to-strong negative relationship was identified between the reduction in torque steadiness following active lengthening and the accompanying AR(p<0.05).Conclusion:It appears that while the RFE-associated AR provides some improved neuromuscular economy,this comes at the cost of increased torque fluctuations in the isometric steady-state following active lengthening during submaximal contractions.展开更多
Cylindrical rollers are important elements of bearings,and their machining accuracy and consistency affect the bearing quality.Using a GCr15 cylindrical roller ofФ11×12 as the processing object in this study,the...Cylindrical rollers are important elements of bearings,and their machining accuracy and consistency affect the bearing quality.Using a GCr15 cylindrical roller ofФ11×12 as the processing object in this study,the effects of loading pressure,abrasive concentration,and speed combination on cylindrical roller machining precision were investigated using the orthogonal experimental design method on a double-side eccentric pendulum lapping and polishing machine.The machining parameters of the lapping stage were optimized,and the lapping optimal process parameters were determined by S/N response analysis and analysis of variance(ANOVA).The results show that when the experiment was optimized using loading pressure of 10 N/roller,abrasive concentrationof 20.0 wt%,and rotational speed combination,the material removal rate(MRR)of cylindrical roller reached 0.0896μm/min;the average roughness of the batch decreased from 0.056μm to 0.027μm,51.8%lower than the original batch average roughness,and the deviation decreased from the initial 0.022μm to 0.014μm;the batch average roundness error decreased from 0.47μm to 0.28μm,40.4%lower than the original batch average roundness error,and the deviation decreased from the initial 0.19μm to 0.038μm;and the batch average diameter variation decreased from 4.5μm to about 3.6μm,20%lower than the original batch average diameter variation.The double-side eccentric lapping of cylinder rollers does not only lead to improvement in the surface quality and shape accuracy of rollers,but also improvement in the batch consistency.展开更多
The eccentric-gear can be used for variable speed transmission.But,due to the vibrations caused by variation of backlash in working process,the eccentric-gear is seldom applied in engineering project.There is just a l...The eccentric-gear can be used for variable speed transmission.But,due to the vibrations caused by variation of backlash in working process,the eccentric-gear is seldom applied in engineering project.There is just a little study about the eccentric-gear.And it is necessary to take a further research on eccentric-gear transmission for the applications in the transplanting mechanism of high-speed rice transplanter.The key of this paper is to extend understanding of three following characteristics of this drive:(1)The rotation-center-distance and the geometrical-center-distance of the two meshing eccentric gears are respectively the hypotenuse and the straight edge of a right triangle in a cycle.(2)The geometrical center line of two meshing gears divides the linking-line of the two rotational centers equally.(3)When two times the eccentricity of gear,the rotation-center-distance and the geometrical-center-distance form a right triangle,the optimal value of rotation-center-distance can be determined.In addition,the kinematic analysis,such as the relationship between contact point and midpoint of the linking-line of two gears'rotational centers,transmission ratio between the driving-gear and the driven-gear,contact angle and coordinate of contact point are be made,further the formula for calculation of contact force,flow chart for writing optimization program and curve for analysis of data are also be developed.The relationship between the rotation-center-distance and the geometrical-center-distance,which is determined by three characteristics mentioned above,is a key for the rational design and application of eccentric-gear transmission.Particularly,the presented right triangle property of eccentric gear drive is an important reference for effective analysis of dynamic characteristic of eccentric-gear mechanism and its reliable design.展开更多
Eccentric decoupling blasting is commonly used in underground excavation.Determination of perimeter hole parameters(such as the blasthole diameter,spacing,and burden)based on an eccentric charge structure is vital for...Eccentric decoupling blasting is commonly used in underground excavation.Determination of perimeter hole parameters(such as the blasthole diameter,spacing,and burden)based on an eccentric charge structure is vital for achieving an excellent smooth blasting effect.In this paper,the Riedel-Hiermaier-Thoma(RHT)model was employed to study rock mass damage under smooth blasting.Firstly,the parameters of the RHT model were calibrated by using the existing SHPB experiment,which were then verified by the existing blasting experiment results.Secondly,the influence of different charge structures on the blasting effect was investigated using the RHT model.The simulation results indicated that eccentric charge blasting has an obvious pressure eccentricity effect.Finally,to improve the blasting effect,the smooth blasting parameters were optimized based on an eccentric charge structure.The overbreak and underbreak phenomena were effectively controlled,and a good blasting effect was achieved with the optimized blasting parameters.展开更多
基金supported by Sichuan Science and Technology Program(Grant No.2020YFH0080)the National Natural Science Foundation of China(Grant No.51475386)the National Basic Research Project of China(973 Program,Grant No.2015CB654801).
文摘The gear transmission system directly affects the operational performance of high-speed trains(HST).However,current research on gear transmission systems of HST often overlooks the effects of gear eccentricity and running resistance,and the dynamic models of gear transmission system are not sufficiently comprehensive.This paper aims to establish an electromechanical coupling dynamic model of HST traction transmission system and study its electromechanical coupling vibration characteristics,in which the internal excitation factors such as gear eccentricity,time-varying meshing stiffness,backlash,meshing error,and external excitation factors such as electromagnetic torque and running resistance are stressed.The research results indicate that gear eccentricity and running resistance have a significant impact on the stability of the system,and gear eccentricity leads to intensified system vibration and decreased anti-interference ability.In addition,the characteristic frequency of gear eccentricity can be extracted from mechanical signals and current signals as a preliminary basis for eccentricity detection,and electrical signals can also be used to monitor changes in train running resistance in real time.The results of this study provide some useful insights into designing dynamic performance parameters for HST transmission systems and monitoring train operational states.
文摘Impairments on body function,activities of daily living(ADL)and cognition are common after stroke.Eccentric resistance training(ERT)may be implemented to improve them.The primary objectives were to evaluate whether ERT improves body function,ADL and cognition after stroke.The secondary objectives were to evaluate whether ERT improves strength,gait,quality of life,and self-perceived health.Seven electronic databases were searched:Cochrane Central Register of Controlled Trials,Cochrane Stroke Group Trials Register,PubMed,Epistemonikos,Embase,SPORTDiscus,and WHO International Clinical Trials Registry Platform.Last search was run in December 2023,including studies since 2012.Selection criteria were studies with stroke participants of both sexes,aged 18 or more,with an intervention based on ERT.Accepted languages were English,Spanish or French.First search was done in pairs.Authors removed duplicate studies and those which did not meet inclusion criteria through title and abstracts.Finally,all authors,independently,screened the final search results and extracted data.Of 68 records identified,15 were eligible and 6 were finally included(with moderate risk of bias),analyzing 159 participants.Body function(4 interventions,n=84),gait(4 interventions,n=115)and strength(3 interventions,n?78)showed significantly better results when ERT was performed.Meta-analysis could not be done because of the few studies and their heterogeneity.This review provided low-moderate quality evidence suggesting that ERT might be effective at improving body function,strength,and gait after stroke.Besides,no harm was documented,and it was well-accepted.
文摘In view of the time-consuming and unreliable deficiencies of the cross-axis work piece in the clamping process,combined with the working characteristics of the eccentric mechanism,a simple and fast eccentric locking mechanism is designed.The push rod iquickly driven by the combined action of the handle and the drum,so that the cross shaft work piece can be quickly locked in the axial direction.The eccentric locking mechanism not only has simple operation and convenient maintenance,but also has the characteristics of low manufacturing cost and high life,and has certain reference value for future special fixture design.
基金Supported by National Natural Science Foundation of China(Grant No.52205455)Fujian Provincial Health Technology Project(Grant Nos.2022CXA005,2022CXA015)。
文摘Cardiovascular disease is the leading cause of human mortality,and calcified tissue blocking blood vessels is the main cause of major adverse cardiovascular events(MACE).Rotational Atherectomy(RA)is a minimally invasive catheterbased treatment method that involves high-speed cutting of calcified tissue using miniature tools for removal.However,the cutting forces,heat,and debris can induce tissue damage and give rise to serious surgical complications.To enhance the effectiveness and efficiency of RA,a novel eccentric rotational cutting tool,with one side comprising axial and circumferential staggered micro-blades,was designed and fabricated in this study.In addition,a series of experiments were conducted to analyze their performance across five dimensions:tool kinematics,force,temperature,debris,and surface morphology of the specimens.Experimental results show that the force,temperature and debris size of the novel tool were well inhibited at the highest rotational speed.For the tool of standard clinical size(diameter 1.25 mm),the maximum force is 0.75 N,with a maximum temperature rise in the operation area of 1.09℃.Debris distribution followed a normal distribution pattern,with 90%of debris measuring smaller than 9.12μm.All tool metrics met clinical safety requirements,indicating its superior performance.This study provides a new idea for the design of calcified tissue removal tools,and contributes positively to the advancement of RA.
文摘Background Serial sarcomere number(SSN)critically influences muscle function and is hypothesized to protect against injury.While most evidence for SSN addition comes from non-human animal studies,eccentric exercise is often proposed as a key stimulus due to its association with increased fascicle length in humans.However,the most efficient exercise stimuli and the effectiveness of eccentric training in increasing SSN remain unclear.The objective of this study was to provide a detailed historical overview of research exploring the mechanical factors regulating muscle/fiber length and its relationship with function,and to explore more recent evidence that eccentric muscle contractions might be an important stimulus for SSN regulation using a meta-analytic approach.Methods An extensive literature search with snowballing was conducted to build the historical review.A systematic review with random-effect meta analyses was performed to compare proposed types of fiber-lengthening exercises to control conditions.Results The historical review demonstrated that the application of forces at long fiber lengths,but not specifically the use of greater excursions,plays an important role in increasing SSN.Animal data showed changes in SSN exceeding 20%over several weeks with varied forms of activities.Nonetheless,the meta-analysis revealed a lack of effect of eccentric resistance training in animal models(Δ=1%;Cohen’s d=0.19(95%confidence interval:–0.29 to 0.67),p=0.449).Conclusion High active or passive muscle forces applied at long fiber lengths appear to be the key stimuli triggering sarcomerogenesis.Eccentric exercise does not seem to be a key promoter of SSN.Too few studies exist to draw conclusions as to the effect of eccentric exercise on SSN in humans.Understanding the mechanical triggers and physiological mechanisms involved in serial sarcomere addition could help in the development of exercise(and other)interventions to optimize muscle function and reduce injury risk.
文摘Sarcomerogenesis,the addition of serial sarcomeres in skeletal muscle myofibrils and fibres,is a natural occurrence during growth and maturation of animals,including humans.However,the detailed mechanisms that allow for sarcomerogenesis are not fully understood.In some diseases,such as cerebral palsy in children,sarcomerogenesis appears to be inhibited or at least reduced,1,2 often causing severe restrictions in muscle and joint function.
文摘The first in vivo measurements of serial sarcomere number in human muscles before and after eccentric strength training have just been published and the results will interest anyone involved with sport or health:Training the hamstrings 3 times per week for 9 weeks with the Nordic hamstring exercise was found to increase the number of sarcomeres in series in the biceps femoris long head(BFlh)by≥25%.1 In this commentary,we highlight an additional,paradoxical finding,which was not discussed by the authors;namely that the substantial serial sarcomere addition must have been accompanied by a subtraction of sarcomeres in parallel to match the relatively small increase in muscle volume after training.
基金Supported in part by Natural Sciences and Engineering Research Council of Canada(NSERC)eMech Systems IncBare Point Water Treatment Plant in Thunder Bay,Ontario,Canada
文摘Induction motors （IMs） are commonly used in various industrial applications. To improve energy con- sumption efficiency, a reliable IM health condition moni- toring system is very useful to detect IM fault at its earliest stage to prevent operation degradation, and malfunction of IMs. An intelligent harmonic synthesis technique is pro- posed in this work to conduct incipient air-gap eccentricity fault detection in IMs. The fault harmonic series are syn- thesized to enhance fault features. Fault related local spectra are processed to derive fault indicators for IM air- gap eccentricity diagnosis. The effectiveness of the pro- posed harmonic synthesis technique is examined experi- mentally by IMs with static air-gap eccentricity and dynamic air-gap eccentricity states under different load conditions. Test results show that the developed harmonic synthesis technique can extract fault features effectively for initial IM air-gap eccentricity fault detection.
基金supported by the National Natural Science Foundation of China(No.50974035)National Natural Science Foundation of China(No.51074047)the doctoral fund of EDU gov(20090407)
文摘In gas injection refining processes, a great amount of gas is injected into molten metal in short time, so that very large bubbles are inevitably formed. Wide dispersion of small bubbles in the bath is indispensable for high refining efficiency. Eccentric mechanical stirring with unidirectional impeller rotation was tested using a water model for pursuing better bubble disintegration and dispersion. Absorption rate are used to research on the influence law of the bubble dispersion and disintegration and gas-liquid absorption by the influence of, rotation mode, rotation speed and gas flow rate. Compared to the experimental results of absorption rate under eccentric stirring and centric stirring ,provide the scientific experimental and theoretical guidance for high-temperature experiment of hot metal desulfurization .According to experimental and theoretical analysis, this paper has studied various factors effecting on gas absorption process and volumetric mass transfer coefficient using the system of CO2-NaOH-H2O.The results show that:the volumetric mass transfer coefficient and absorption efficiency of CO2 can be increased under eccentric stirring mode, Because bubble disperse quickly with eccentric mechanical stirring, which results in promoting complete reaction between CO2 and NaOH, and improving the mass transfer coefficient and absorption. Volumetric mass transfer coefficient and efficiency of CO2 increase with the increasing rotation speed under the condition of eccentric stirring .But volumetric mass transfer coefficient and efficiency of CO2 decrease with the increasing rotation speed under the condition of centric stirring.
基金National Natural Science Foundation of China(No.50875243)
文摘A novel weft insertion mechanism named eccentric conjugate non-circular gear & crank-rocker & gears train weft insertion mechanism was proposed in order to better meet the requirements of rapier loom's weft insertion mechanism as well as reduce the manufacturing difficulty. Meanwhile, based on the working principle of this mechanism, kinematical mathematic models of this mechanism were established and an aided analysis and simulation software was compiled. The influences of eccentricity ratio, deformation coefficient, and other important parameters on the kinematics characteristics of this mechanism were analyzed by using the software. A group of preferable parameters which could meet the requirements of weft insertion technology were obtained by means of human-computer interactive optimization method. The maximum velocity, maximum acceleration, and variation of acceleration of this mechanism are smaller than those of the conjugate cam weft insertion mechanism applied on TT96 rapier loom under the conditions of the same unilateral total stroke of rapier head and the same rotary speed of loom spindle; meanwhile the other demands of weaving technology can be met by this novel weft insertion mechanism.
基金Item Sponsored by Polish State Committee for Scientific Research(N50802431/1444)
文摘A new concept for forming eccentric shafts on the basis of the cross-wedge rolling （CWR） process was presented. This concept was based on the application of special guides, which, by acting on a billet, lead to its controlled movement in the vertical direction. This movement made possible eccentric cutting of tools into the billet. FEM calculations and experimental rolling tests clearly confirmed the effectiveness of the proposed forming method.
基金supported by the National Natural Science Foundation of China [grant number 11772059]the National KeyResearch and Development Program of China [grant number 2017yfc0822300]+1 种基金the 111 Project[grant number G20012017001]the Foundation of State Key Laboratory of Explosion Science and Technology of China[grant number KFJJ13-1Z]
文摘With the technical development of new warhead designs and improvised explosive device protection,irregular casing filled with explosive has been paid more attention recently. In this paper, we studied the fragmentation of a type of D-shaped casing, which is a common asymmetric casing in the field of warhead design. Based on the radiograph technique, static explosive experiments were conducted with D-shaped casings under four different eccentric initiation ratios to explore their fragmentation. A numerical model was then established to simulate the dynamic response of D-shaped casing filled with explosive. The results of numerical simulation were found to agree well with the experimental data.According to the results of numerical simulation and experimental data, the dynamic responses of Dshaped casing were analyzed. The results of the current work pave way for the innovative design of new warhead and for further studying the dynamic response of asymmetric casing.
基金Item Sponsored by National Natural Science Foundation of China (60774032)Provincial Natural Science Foundation of Guangdong Province of China (06025724)+1 种基金Key Project of Guangzhou Scientific Program of China (2007Z2-D0121)Special Research Fund of Ministry of Education of China for College Doctoral Subjects (20070561006)
文摘Roll eccentricity is an important factor causing thickness variations during hot strip rolling and might define the limit of strip thickness control accuracy. An improved multi-resolution wavelet transform algorithm was proposed to compensate for the roll eccentricity. The wavelet transform method had good localization characteristics in both the time and frequency domains for signal analysis; however, the wavelet method had a frequency-aliasing problem owing to the less than ideal cut-off frequency characteristics of wavelets. This made its component reconstruction of an inaccurate signal. To eliminate inherent frequency aliases in the wavelet transform, fast Fourier transform （FFT） and inverse fast Fourier transform （IFFT） were combined with the Mallat algorithm. This synthesis was described in detail. Then, the roll eccentricity component was extracted from rolling force signal. An automatic gauge control （AGC） system added with a multi-resolution wavelet analyzer was designed. Experimental results showed that the anti-aliasing method could greatly restrain the inverse effect of eccentricity and the thickness control accuracy was improved from ±40 μm to ±15 μm.
文摘Neuromuscular activity is suppressed during maximal eccentric(ECC)muscle contraction in untrained subjects owing to attenuated levels of central activation and reduced spinal motor neuron(MN)excitability indicated by reduced electromyography signal amplitude,diminished evoked H-reflex responses,increased autogenic MN inhibition,and decreased excitability in descending corticospinal motor pathways.Maximum ECC muscle force recorded during maximal voluntary contraction can be increased by superimposed electrical muscle stimulation only in untrained individuals and not in trained strength athletes,indicating that the suppression in MN activation is modifiable by resistance training.In support of this notion,maximum ECC muscle strength can be increased by use of heavy-load resistance training owing to a removed or diminished suppression in neuromuscular activity.Prolonged(weeks to months)of heavy-load resistance training results in increased H-reflex and V-wave responses during maximal ECC muscle actions along with marked gains in maximal ECC muscle strength,indicating increased excitability of spinal MNs,decreased presynaptic and/or postsynaptic MN inhibition,and elevated descending motor drive.Notably,the use of supramaximal ECC resistance training can lead to selectively elevated V-wave responses during maximal ECC contraction,demonstrating that adaptive changes in spinal circuitry function and/or gains in descending motor drive can be achieved during maximal ECC contraction in response to heavy-load resistance training.
文摘The forced lengthening of an activated skeletal muscle has been termed an eccentric contraction(EC).This review highlights the mechanically unique nature of the EC and focuses on the specific disruption of proteins within the cell known as cytoskeletal proteins.The major intermediate filament cytoskeletal protein,desmin,has been the focus of work in this area because changes to desmin occur within minutes of ECs and because desmin has been shown to play both a mechanical and biologic role in a muscle's response to EC.It is hoped that these types of studies will assist in decreasing the incidence of muscle injury in athletes and facilitating the development of new therapies to treat muscle injuries.
基金supported by the Natural Sciences and Engineering Research Council of Canada
文摘Background:The isometric steady-state following active lengthening is associated with greater torque production and lower activation,as measured by electromyographic activity(EMG),in comparison with a purely isometric contraction(ISO)at the same joint angle.This phenomenon is termed residual force enhancement(RFE).While there has been a great deal of research investigating the basic mechanisms of RFE,little work has been performed to understand the everyday relevance of RFE.The purpose of this study was to investigate whether neuromuscular control strategies differ between ISO and RFE by measuring torque steadiness of the human ankle plantar flexors.Methods:Following ISO maximal voluntary contractions in 12 males(25±4 years),an active lengthening contraction was performed at 15°/s over a 30°ankle excursion,ending at the same joint angle as ISO(5°dorsiflexion;RFE).Surface EMG of the tibialis anterior and soleus muscles was recorded during all tasks.Torque steadiness was determined as the standard deviation(SD)and coefficient of variation(CV)of the torque trace in the ISO and RFE condition during activation-matching(20%and 60%integrated EMG)and torque-matching(20%and 60%maximal voluntary contraction)experiments.Two-tailed,paired t tests were used,within subjects,to determine the presence of RFE/activation reduction(AR)and whether there was a difference in torque steadiness between ISO and RFE conditions.Results:During the maximal and submaximal conditions,there was 5%-9%RFE with a 9%-11%AR(p<0.05),respectively,with no difference in antagonist coactivation between RFE and ISO(p>0.05).There were no differences in SD and CV of the torque trace for the 20%and60%activation-matching or the 60%and maximal torque-matching trials in either the RFE or ISO condition(p>0.05).During the 20%torquematching trial,there were～37%higher values for SD and CV in the RFE as compared with the ISO condition(p<0.05).A significant moderate-to-strong negative relationship was identified between the reduction in torque steadiness following active lengthening and the accompanying AR(p<0.05).Conclusion:It appears that while the RFE-associated AR provides some improved neuromuscular economy,this comes at the cost of increased torque fluctuations in the isometric steady-state following active lengthening during submaximal contractions.
基金supported by National Natural Science Foundation of China (Grant No.51175468,U1401247)Public Welfare Industry Project of Zhejiang Provincial Science and Technology Department (Grant no.20160069)
文摘Cylindrical rollers are important elements of bearings,and their machining accuracy and consistency affect the bearing quality.Using a GCr15 cylindrical roller ofФ11×12 as the processing object in this study,the effects of loading pressure,abrasive concentration,and speed combination on cylindrical roller machining precision were investigated using the orthogonal experimental design method on a double-side eccentric pendulum lapping and polishing machine.The machining parameters of the lapping stage were optimized,and the lapping optimal process parameters were determined by S/N response analysis and analysis of variance(ANOVA).The results show that when the experiment was optimized using loading pressure of 10 N/roller,abrasive concentrationof 20.0 wt%,and rotational speed combination,the material removal rate(MRR)of cylindrical roller reached 0.0896μm/min;the average roughness of the batch decreased from 0.056μm to 0.027μm,51.8%lower than the original batch average roughness,and the deviation decreased from the initial 0.022μm to 0.014μm;the batch average roundness error decreased from 0.47μm to 0.28μm,40.4%lower than the original batch average roundness error,and the deviation decreased from the initial 0.19μm to 0.038μm;and the batch average diameter variation decreased from 4.5μm to about 3.6μm,20%lower than the original batch average diameter variation.The double-side eccentric lapping of cylinder rollers does not only lead to improvement in the surface quality and shape accuracy of rollers,but also improvement in the batch consistency.
基金supported by National Basic Research Program of China(973 Program,Grant No.2004CCA05700)National Natural Science Foundation of China(Grant No.50875244)Zhejiang Provincial Natural Science Foundation of China(Grant No.Z105706)
文摘The eccentric-gear can be used for variable speed transmission.But,due to the vibrations caused by variation of backlash in working process,the eccentric-gear is seldom applied in engineering project.There is just a little study about the eccentric-gear.And it is necessary to take a further research on eccentric-gear transmission for the applications in the transplanting mechanism of high-speed rice transplanter.The key of this paper is to extend understanding of three following characteristics of this drive:(1)The rotation-center-distance and the geometrical-center-distance of the two meshing eccentric gears are respectively the hypotenuse and the straight edge of a right triangle in a cycle.(2)The geometrical center line of two meshing gears divides the linking-line of the two rotational centers equally.(3)When two times the eccentricity of gear,the rotation-center-distance and the geometrical-center-distance form a right triangle,the optimal value of rotation-center-distance can be determined.In addition,the kinematic analysis,such as the relationship between contact point and midpoint of the linking-line of two gears'rotational centers,transmission ratio between the driving-gear and the driven-gear,contact angle and coordinate of contact point are be made,further the formula for calculation of contact force,flow chart for writing optimization program and curve for analysis of data are also be developed.The relationship between the rotation-center-distance and the geometrical-center-distance,which is determined by three characteristics mentioned above,is a key for the rational design and application of eccentric-gear transmission.Particularly,the presented right triangle property of eccentric gear drive is an important reference for effective analysis of dynamic characteristic of eccentric-gear mechanism and its reliable design.
基金Projects(11802058,52074262)supported by the National Natural Science Foundation of ChinaProjects(BK20170670,BK20180651)supported by the Jiangsu Youth Foundation,China+2 种基金Project(2020QN06)supported by the Fundamental Research Funds for the Central Universities,ChinaProject(SKLGDUEK1803)supported by the State Key Laboratory for Geomechanics and Deep Underground Engineering,ChinaProject supported by the Mass Entrepreneurship and Innovation Project of Jiangsu,China。
文摘Eccentric decoupling blasting is commonly used in underground excavation.Determination of perimeter hole parameters(such as the blasthole diameter,spacing,and burden)based on an eccentric charge structure is vital for achieving an excellent smooth blasting effect.In this paper,the Riedel-Hiermaier-Thoma(RHT)model was employed to study rock mass damage under smooth blasting.Firstly,the parameters of the RHT model were calibrated by using the existing SHPB experiment,which were then verified by the existing blasting experiment results.Secondly,the influence of different charge structures on the blasting effect was investigated using the RHT model.The simulation results indicated that eccentric charge blasting has an obvious pressure eccentricity effect.Finally,to improve the blasting effect,the smooth blasting parameters were optimized based on an eccentric charge structure.The overbreak and underbreak phenomena were effectively controlled,and a good blasting effect was achieved with the optimized blasting parameters.
