In recent years,feature selection(FS)optimization of high-dimensional gene expression data has become one of the most promising approaches for cancer prediction and classification.This work reviews FS and classificati...In recent years,feature selection(FS)optimization of high-dimensional gene expression data has become one of the most promising approaches for cancer prediction and classification.This work reviews FS and classification methods that utilize evolutionary algorithms(EAs)for gene expression profiles in cancer or medical applications based on research motivations,challenges,and recommendations.Relevant studies were retrieved from four major academic databases-IEEE,Scopus,Springer,and ScienceDirect-using the keywords‘cancer classification’,‘optimization’,‘FS’,and‘gene expression profile’.A total of 67 papers were finally selected with key advancements identified as follows:(1)The majority of papers(44.8%)focused on developing algorithms and models for FS and classification.(2)The second category encompassed studies on biomarker identification by EAs,including 20 papers(30%).(3)The third category comprised works that applied FS to cancer data for decision support system purposes,addressing high-dimensional data and the formulation of chromosome length.These studies accounted for 12%of the total number of studies.(4)The remaining three papers(4.5%)were reviews and surveys focusing on models and developments in prediction and classification optimization for cancer classification under current technical conditions.This review highlights the importance of optimizing FS in EAs to manage high-dimensional data effectively.Despite recent advancements,significant limitations remain:the dynamic formulation of chromosome length remains an underexplored area.Thus,further research is needed on dynamic-length chromosome techniques for more sophisticated biomarker gene selection techniques.The findings suggest that further advancements in dynamic chromosome length formulations and adaptive algorithms could enhance cancer classification accuracy and efficiency.展开更多
Entanglement asymmetry(EA) has emerged as a powerful tool for characterizing symmetry breaking in quantum many-body systems. In this Letter, we explore how symmetry is dynamically broken through the lens of EA in two ...Entanglement asymmetry(EA) has emerged as a powerful tool for characterizing symmetry breaking in quantum many-body systems. In this Letter, we explore how symmetry is dynamically broken through the lens of EA in two distinct scenarios: a non-symmetric Hamiltonian quench and a non-symmetric random quantum circuit, with a particular focus on U(1) symmetry. In the former case, symmetry remains broken in the subsystem at late times, whereas in the latter case, the symmetry is initially broken and subsequently restored, consistent with the principles of quantum thermalization. Notably, the growth of EA exhibits unexpected overshooting behavior at early times in both contexts, contrasting with the behavior of charge variance. We also consider dynamics of non-symmetric initial states under the symmetry-breaking evolution. Due to the competition of symmetry-breaking in both the initial state and Hamiltonian, the early-time EA can increase and decrease, while quantum Mpemba effects remain evident despite the weak symmetry-breaking in both settings.展开更多
基金funded by the Ministry of Higher Education of Malaysia,grant number FRGS/1/2022/ICT02/UPSI/02/1.
文摘In recent years,feature selection(FS)optimization of high-dimensional gene expression data has become one of the most promising approaches for cancer prediction and classification.This work reviews FS and classification methods that utilize evolutionary algorithms(EAs)for gene expression profiles in cancer or medical applications based on research motivations,challenges,and recommendations.Relevant studies were retrieved from four major academic databases-IEEE,Scopus,Springer,and ScienceDirect-using the keywords‘cancer classification’,‘optimization’,‘FS’,and‘gene expression profile’.A total of 67 papers were finally selected with key advancements identified as follows:(1)The majority of papers(44.8%)focused on developing algorithms and models for FS and classification.(2)The second category encompassed studies on biomarker identification by EAs,including 20 papers(30%).(3)The third category comprised works that applied FS to cancer data for decision support system purposes,addressing high-dimensional data and the formulation of chromosome length.These studies accounted for 12%of the total number of studies.(4)The remaining three papers(4.5%)were reviews and surveys focusing on models and developments in prediction and classification optimization for cancer classification under current technical conditions.This review highlights the importance of optimizing FS in EAs to manage high-dimensional data effectively.Despite recent advancements,significant limitations remain:the dynamic formulation of chromosome length remains an underexplored area.Thus,further research is needed on dynamic-length chromosome techniques for more sophisticated biomarker gene selection techniques.The findings suggest that further advancements in dynamic chromosome length formulations and adaptive algorithms could enhance cancer classification accuracy and efficiency.
基金the support of the International Young Scientist Fellowship of the Institute of Physics,Chinese Academy of Sciences (Grant No.202407)supported by the Innovation Program for Quantum Science and Technology (Grant No.2024ZD0301700)+1 种基金the start-up grant at IOP-CAS.ZXL is supported by the Beijing Natural Science Foundation (Grant No.JR25007)the National Natural Science Foundation of China (Grants No.12347107and 12474146)。
文摘Entanglement asymmetry(EA) has emerged as a powerful tool for characterizing symmetry breaking in quantum many-body systems. In this Letter, we explore how symmetry is dynamically broken through the lens of EA in two distinct scenarios: a non-symmetric Hamiltonian quench and a non-symmetric random quantum circuit, with a particular focus on U(1) symmetry. In the former case, symmetry remains broken in the subsystem at late times, whereas in the latter case, the symmetry is initially broken and subsequently restored, consistent with the principles of quantum thermalization. Notably, the growth of EA exhibits unexpected overshooting behavior at early times in both contexts, contrasting with the behavior of charge variance. We also consider dynamics of non-symmetric initial states under the symmetry-breaking evolution. Due to the competition of symmetry-breaking in both the initial state and Hamiltonian, the early-time EA can increase and decrease, while quantum Mpemba effects remain evident despite the weak symmetry-breaking in both settings.