Liver biopsy is rarely performed for the diagnosis of compensated advanced chronic liver disease(cACLD)in the current clinical hepatology practice.In the early stage,cACLD presents without portal hypertension,and in t...Liver biopsy is rarely performed for the diagnosis of compensated advanced chronic liver disease(cACLD)in the current clinical hepatology practice.In the early stage,cACLD presents without portal hypertension,and in the later stage,it presents with portal hypertension.Hepatic venous pressure gradient measu-rement is the gold standard for diagnosing portal hypertension,but it is rarely used due to its invasive nature.The recent Baveno VII consensus recommends a noninvasive strategy for the diagnosis of cACLD and clinically significant portal hypertension(CSPH).However,there is some uncertainty regarding the dia-gnostic accuracy of Baveno VII criteria for predicting CSPH among patients with metabolic dysfunction-associated steatotic liver disease(MASLD).This is per-tinent as MASLD has become the most important cause of cACLD in the United States.This mini-review outlines the diagnostic performance of Baveno VII cri-teria and other noninvasive criteria for predicting CSPH in patients with cACLD from MASLD compared to non-MASLD causes.展开更多
文摘Liver biopsy is rarely performed for the diagnosis of compensated advanced chronic liver disease(cACLD)in the current clinical hepatology practice.In the early stage,cACLD presents without portal hypertension,and in the later stage,it presents with portal hypertension.Hepatic venous pressure gradient measu-rement is the gold standard for diagnosing portal hypertension,but it is rarely used due to its invasive nature.The recent Baveno VII consensus recommends a noninvasive strategy for the diagnosis of cACLD and clinically significant portal hypertension(CSPH).However,there is some uncertainty regarding the dia-gnostic accuracy of Baveno VII criteria for predicting CSPH among patients with metabolic dysfunction-associated steatotic liver disease(MASLD).This is per-tinent as MASLD has become the most important cause of cACLD in the United States.This mini-review outlines the diagnostic performance of Baveno VII cri-teria and other noninvasive criteria for predicting CSPH in patients with cACLD from MASLD compared to non-MASLD causes.
