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Dynamic ventilation functional MRI of the lung with sub-millimeter spatial resolution and millisecond temporal resolution
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作者 Hongchuang Li Haidong Li +8 位作者 Ming Zhang Xiaoling Liu Xiuchao Zhao Yeqing Han Yang Jin Li Fan Louis-S.Bouchard Shiyuan Liu Xin Zhou 《Science Bulletin》 2025年第24期4142-4145,共4页
Pulmonary dynamic ventilation dysfunction is a common feature of various lung diseases,including chronic obstructive pulmonary disease(COPD)[1],cystic fibrosis[2],and asthma[3].Regional assessment of ventilation dynam... Pulmonary dynamic ventilation dysfunction is a common feature of various lung diseases,including chronic obstructive pulmonary disease(COPD)[1],cystic fibrosis[2],and asthma[3].Regional assessment of ventilation dynamics offers substantial potential to enhance diagnostic accuracy and therapeutic monitoring in these conditions.Although current clinical evaluations primarily depend on global pulmonary function tests,emerging imaging modalities such as four-dimensional computed tomography(4D-CT)[4]and phase-resolved functional lung(PREFUL)imaging[5]enable temporal observation of structural and ventilation changes. 展开更多
关键词 imaging modalities functional MRI lung diseasesincluding enhance diagnostic accuracy therapeutic monitoring asthma regional assessment ventilation dynamics chronic obstructive pulmonary disease copd cystic fibrosis pulmonary dynamic ventilation dysfunction global pulmonary function testsemerging
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Predicting indoor particle dispersion under dynamic ventilation modes with high-order Markov chain model 被引量:1
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作者 Xiong Mei Chenni Zeng Guangcai Gong 《Building Simulation》 SCIE EI CSCD 2022年第7期1243-1258,共16页
Mechanical and natural ventilations are effective measures to remove indoor airborne contaminants,thereby creating improved indoor air quality(IAQ).Among various simulation techniques,Markov chain model is a relativel... Mechanical and natural ventilations are effective measures to remove indoor airborne contaminants,thereby creating improved indoor air quality(IAQ).Among various simulation techniques,Markov chain model is a relatively new and efficient method in predicting indoor airborne pollutants.The existing Markov chain model(for indoor airborne pollutants)is basically assumed as first-order,which however is difficult to deal with airborne particles with non-negligible inertial.In this study,a novel weight-factor-based high-order(second-order and third-order)Markov chain model is developed to simulate particle dispersion and deposition indoors under fixed and dynamic ventilation modes.Flow fields under various ventilation modes are solved by computational fluid dynamics(CFD)tools in advance,and then the basic first-order Markov chain model is implemented and validated by both simulation results and experimental data from literature.Furthermore,different groups of weight factors are tested to estimate appropriate weight factors for both second-order and third-order Markov chain models.Finally,the calculation process is properly designed and controlled,so that the proposed high-order(second-order)Markov chain model can be used to perform particle-phase simulation under consecutively changed ventilation modes.Results indicate that the proposed second-order model does well in predicting particle dispersion and deposition under fixed ventilation mode as well as consecutively changed ventilation modes.Compared with traditional first-order Markov chain model,the proposed high-order model performs with more reasonable accuracy but without significant computing cost increment.The most suitable weight factors of the simulation case in this study are found to be(λ_(1)=0.7,λ_(2)=0.3,λ_(3)=0)for second-order Markov chain model,and(λ_(1)=0.8,λ_(2)=0.1,λ_(3)=0.1)for third-order Markov chain model in terms of reducing errors in particle deposition and escape prediction.With the improvements of the efficiency of state transfer matrix construction and flow field data acquisition/processing,the proposed high-order Markov chain model is expected to provide an alternative choice for fast prediction of indoor airborne particulate(as well as gaseous)pollutants under transient flows. 展开更多
关键词 high-order Markov chain dynamic ventilation modes indoor particles particle dispersion fast prediction
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Comparison of direct and indirect determinations of dynamic ventilation rate in a modern dairy free stall barn
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作者 Bing Zou Albert J.Heber +3 位作者 Zhengxiang Shi Songhuai Du Yaomin Jin Teng Teeh Lim 《International Journal of Agricultural and Biological Engineering》 SCIE EI CAS 2020年第6期41-46,共6页
Reliable estimation of the ventilation rate(VR)in intensive livestock buildings is necessary for studying building environmental control strategies and predicting indoor air quality and air emissions.As direct air exc... Reliable estimation of the ventilation rate(VR)in intensive livestock buildings is necessary for studying building environmental control strategies and predicting indoor air quality and air emissions.As direct air exchange measurements are time-consuming and expensive,it is environmentally inefficient to measure livestock building VR continuously in practice.Hence,indirect VR estimation methods have been widely used in modelling environmental control and air emissions,and also to measure airflow in the field.The accuracy of indirect measurement methods needs to be evaluated by comparing with direct measurements.In this study,the direct and indirect methods of determining hourly and daily mean VRs were applied to a mechanically-ventilated dairy free stall barn monitored by the 24-month National Air Emissions Monitoring Study.The direct method was used to continuously monitor fan rotational speeds,and differential static pressures,coupled with periodic in-situ fan performance assessments,to calculate the VR.The indirect method consisted of estimating the VR using CO2 concentration measurements and the CO2 mass balance method.The average daily and hourly means(mean±SD)of directly measured barn ventilation rates for two years were(246±73)m3/s and(245±77)m3/s,respectively.The average daily and hourly means(mean±SD)of barn ventilation rates estimated by the CO2 mass balance method were(287±93.4)m3/s and(287±118)m3/s,respectively.Correlation analyses showed a strong correlation between the indirect CO2 mass balance method and direct measurement methods(r=0.93 for daily means and r=0.85 for hourly means). 展开更多
关键词 dynamic ventilation rate modern dairy free stall barn carbon dioxide mass balance dairy cow direct and indirect determination comparison
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Effect of single dead end entry inclination on DPM plume dispersion 被引量:3
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作者 Zheng Yi Lan Hai +2 位作者 Thiruvengadam Magesh Tien Jerry C. Li Ying 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2017年第3期401-406,共6页
Diesel particulate matter(DPM) is a by-product from operating diesel engines. Since diesel powers are one of the major sources of energy for mobile underground mining equipment, the adverse health effects of DPM are o... Diesel particulate matter(DPM) is a by-product from operating diesel engines. Since diesel powers are one of the major sources of energy for mobile underground mining equipment, the adverse health effects of DPM are of a great concern. This paper used computational fluid dynamics(CFD) method to study the effect of entry inclination on DPM plume distribution in a dead end entry. An upward mining face and a downward mining face were built with a truck and a loader in loading operation close to the face area. A species transport model with incorporated buoyancy effect was used to examine the DPM dispersion pattern for the above steady-state scenarios. High DPM and temperature regions were identified for the two different faces. The model was used to assess the role of auxiliary ventilation in reducing DPM exposures of underground miners working in those entries. In this study, it is suggested to provide local ventilation at least three times of the diesel exhaust rate to be able to lower the average DPM level for the mining upward face. The requirement for local ventilation is much less for the mining downward face. This can provide guidelines for good working practices and selection of diesel emission reduction technologies underground. 展开更多
关键词 Entry inclination Diesel particulate matter Computational fluid dynamics ventilation
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Evaluation of line brattice length in an empty heading to improve air flow rate at the face using CFD 被引量:3
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作者 Feroze Tariq Genc Bekir 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2017年第2期253-259,共7页
The effectiveness of line brattice(LB) ventilation system depends on the associated system variables.However, the effect of these variables on the air flow rates close to the face of the heading is not extensively stu... The effectiveness of line brattice(LB) ventilation system depends on the associated system variables.However, the effect of these variables on the air flow rates close to the face of the heading is not extensively studied. In this paper, the effect of the LB length in relation to the LB-wall distance on the air flow rate reaching the face is analysed. Scenarios were developed using four LB lengths, two LB-wall distances and two heading depths. These scenarios were simulated with a validated CFD model. The air flow rates and patterns at various locations inside the heading were analysed. This helped to find the minimum LB-face distance that should be maintained for each LB-wall distance to maximise the air flow rate at the face. The minimum length when used will improve ventilation and reduce energy cost. 展开更多
关键词 Coal mine ventilation Auxiliary ventilation Line brattice ventilation system Computational fluid dynamics
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