Janus vesicles,unique nanostructures,have attracted significant attention for their diverse applications in biomedical and microfluidic systems.In practical micro-nano systems,flow and electric fields often coexist,an...Janus vesicles,unique nanostructures,have attracted significant attention for their diverse applications in biomedical and microfluidic systems.In practical micro-nano systems,flow and electric fields often coexist,and the perforation dynamics of Janus vesicles exhibit complex motion due to their synergistic effects.Studying Janus vesicle perforation dynamics under the combined influence of fluid flow and electric fields provides valuable insights into their applications in drug delivery,catalyst delivery,and controlled release.This study focuses on the perforation dynamics and directional motion of Janus vesicles in microchannels,emphasizing how electric field strength and charge distribution on the membrane influence vesicle migration,deformation,and trajectories.Results show that when electromagnetic forces and flow-driven forces align,increasing electric field strength promotes vesicle migration and perforation.Vesicle migration is correlated with charge distribution on the membrane,with broader distributions resulting in more pronounced migration.When electric field strength remains constant,charge distribution has little effect on vesicle deformation.Conversely,when electromagnetic forces and flow-driven forces oppose,increasing electric field strength inhibits vesicle migration.At a specific potential difference,charged vesicles cease movement before reaching the perforation site,indicating the critical potential for perforation.The study also reveals that the direction of the electric field significantly affects vesicle migration direction.Adjusting potential values at microchannel boundaries can control the directional movement of Janus vesicles.This research provides new insights into Janus vesicle behavior in complex environments and deepens understanding of their potential as drug carriers for delivery and targeted therapy.展开更多
The pressure loss of cross-flow perforated of physical modeling, simulation and data processing. muffler has been computed with the procedure Three-dimensional computational fluid dynamics （CFD） has been used to inv...The pressure loss of cross-flow perforated of physical modeling, simulation and data processing. muffler has been computed with the procedure Three-dimensional computational fluid dynamics （CFD） has been used to investigate the relations of porosities, flow velocity and diameter of the holes with the pressure loss. Accordingly, some preliminary results have been obtained that pressure loss increases with porosity descent as nearly a hyperbolic trend, rising flow velocity of the input makes the pressure loss increasing with parabola trend, diameter of holes affects little about pressure loss of the muffler. Otherwise, the holes on the perforated pipes make the air flow gently and meanly, which decreases the air impact to the wall and pipes in the muffler. A practical perforated muffler is used to illustrate the available of this method for pressure loss computation, and the comparison shows that the computation results with the method of CFD has reference value for muffler design.展开更多
基金financially supported by the National Natural Science Foundation of China(No.2247030172)。
文摘Janus vesicles,unique nanostructures,have attracted significant attention for their diverse applications in biomedical and microfluidic systems.In practical micro-nano systems,flow and electric fields often coexist,and the perforation dynamics of Janus vesicles exhibit complex motion due to their synergistic effects.Studying Janus vesicle perforation dynamics under the combined influence of fluid flow and electric fields provides valuable insights into their applications in drug delivery,catalyst delivery,and controlled release.This study focuses on the perforation dynamics and directional motion of Janus vesicles in microchannels,emphasizing how electric field strength and charge distribution on the membrane influence vesicle migration,deformation,and trajectories.Results show that when electromagnetic forces and flow-driven forces align,increasing electric field strength promotes vesicle migration and perforation.Vesicle migration is correlated with charge distribution on the membrane,with broader distributions resulting in more pronounced migration.When electric field strength remains constant,charge distribution has little effect on vesicle deformation.Conversely,when electromagnetic forces and flow-driven forces oppose,increasing electric field strength inhibits vesicle migration.At a specific potential difference,charged vesicles cease movement before reaching the perforation site,indicating the critical potential for perforation.The study also reveals that the direction of the electric field significantly affects vesicle migration direction.Adjusting potential values at microchannel boundaries can control the directional movement of Janus vesicles.This research provides new insights into Janus vesicle behavior in complex environments and deepens understanding of their potential as drug carriers for delivery and targeted therapy.
文摘The pressure loss of cross-flow perforated of physical modeling, simulation and data processing. muffler has been computed with the procedure Three-dimensional computational fluid dynamics （CFD） has been used to investigate the relations of porosities, flow velocity and diameter of the holes with the pressure loss. Accordingly, some preliminary results have been obtained that pressure loss increases with porosity descent as nearly a hyperbolic trend, rising flow velocity of the input makes the pressure loss increasing with parabola trend, diameter of holes affects little about pressure loss of the muffler. Otherwise, the holes on the perforated pipes make the air flow gently and meanly, which decreases the air impact to the wall and pipes in the muffler. A practical perforated muffler is used to illustrate the available of this method for pressure loss computation, and the comparison shows that the computation results with the method of CFD has reference value for muffler design.
