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Aberrant dynamic functional connectivity of thalamocortical circuitry in major depressive disorder
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作者 Weihao ZHENG Qin ZHANG +7 位作者 Ziyang ZHAO Pengfei ZHANG Leilei ZHAO Xiaomin WANG Songyu YANG Jing ZHANG Zhijun YAO Bin HU 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2024年第10期857-877,共21页
Thalamocortical circuitry has a substantial impact on emotion and cognition.Previous studies have demonstrated alterations in thalamocortical functional connectivity(FC),characterized by region-dependent hypo-or hyper... Thalamocortical circuitry has a substantial impact on emotion and cognition.Previous studies have demonstrated alterations in thalamocortical functional connectivity(FC),characterized by region-dependent hypo-or hyper-connectivity,among individuals with major depressive disorder(MDD).However,the dynamical reconfiguration of the thalamocortical system over time and potential abnormalities in dynamic thalamocortical connectivity associated with MDD remain unclear.Hence,we analyzed dynamic FC(dFC)between ten thalamic subregions and seven cortical subnetworks from resting-state functional magnetic resonance images of 48 patients with MDD and 57 healthy controls(HCs)to investigate time-varying changes in thalamocortical FC in patients with MDD.Moreover,dynamic laterality analysis was conducted to examine the changes in functional lateralization of the thalamocortical system over time.Correlations between the dynamic measures of thalamocortical FC and clinical assessment were also calculated.We identified four dynamic states of thalamocortical circuitry wherein patients with MDD exhibited decreased fractional time and reduced transitions within a negative connectivity state that showed strong correlations with primary cortical networks,compared with the HCs.In addition,MDD patients also exhibited increased fluctuations in functional laterality in the thalamocortical system across the scan duration.The thalamo-subnetwork analysis unveiled abnormal dFC variability involving higher-order cortical networks in the MDD cohort.Significant correlations were found between increased dFC variability with dorsal attention and default mode networks and the severity of symptoms.Our study comprehensively investigated the pattern of alteration of the thalamocortical dFC in MDD patients.The heterogeneous alterations of dFC between the thalamus and both primary and higher-order cortical networks may help characterize the deficits of sensory and cognitive processing in MDD. 展开更多
关键词 Major depressive disorder Resting-state functional magnetic resonance imaging Thalamocortical circuitry dynamic functional connectivity dynamic laterality
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On dynamic function of cognitive context 被引量:2
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作者 许葵花 《Sino-US English Teaching》 2007年第8期42-46,共5页
Sperber & Wilson point out the cognitive nature of context when they explicate relevance theory. Cognitive context exerts its function dynamically. The process of communication is the participation of cognitive conte... Sperber & Wilson point out the cognitive nature of context when they explicate relevance theory. Cognitive context exerts its function dynamically. The process of communication is the participation of cognitive context. Without cognitive context, the verbal communication can not be realized. 展开更多
关键词 cognitive context dynamic function
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Abnormal characterization of dynamic functional connectivity in Alzheimer’s disease 被引量:12
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作者 Cui Zhao Wei-Jie Huang +7 位作者 Feng Feng Bo Zhou Hong-Xiang Yao Yan-E Guo Pan Wang Lu-Ning Wang Ni Shu Xi Zhang 《Neural Regeneration Research》 SCIE CAS CSCD 2022年第9期2014-2021,共8页
Numerous studies have shown abnormal brain functional connectivity in individuals with Alzheimer’s disease(AD)or amnestic mild cognitive impairment(aMCI).However,most studies examined traditional resting state functi... Numerous studies have shown abnormal brain functional connectivity in individuals with Alzheimer’s disease(AD)or amnestic mild cognitive impairment(aMCI).However,most studies examined traditional resting state functional connections,ignoring the instantaneous connection mode of the whole brain.In this case-control study,we used a new method called dynamic functional connectivity(DFC)to look for abnormalities in patients with AD and aMCI.We calculated dynamic functional connectivity strength from functional magnetic resonance imaging data for each participant,and then used a support vector machine to classify AD patients and normal controls.Finally,we highlighted brain regions and brain networks that made the largest contributions to the classification.We found differences in dynamic function connectivity strength in the left precuneus,default mode network,and dorsal attention network among normal controls,aMCI patients,and AD patients.These abnormalities are potential imaging markers for the early diagnosis of AD. 展开更多
关键词 Alzheimer’s disease amnestic mild cognitive impairment blood oxygen level-dependent default mode network dynamic functional connectivity frontoparietal network resting-state functional magnetic resonance imaging support vector machine
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An Improved GT Algorithm for Solving Complicated Dynamic Function Optimization Problems
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作者 ZHANG Qing LI Yan +1 位作者 KANG Zhuo KANG Lishan 《Wuhan University Journal of Natural Sciences》 CAS 2009年第5期404-408,共5页
An improved Guo Tao algorithm (IGT algorithm) is proposed for solving complicated dynamic function optimization problems, and a function optimization benchmark problem with constrained condition and two dynamic para... An improved Guo Tao algorithm (IGT algorithm) is proposed for solving complicated dynamic function optimization problems, and a function optimization benchmark problem with constrained condition and two dynamic parameters has been designed. The results achieved by IGT algorithm have been compared with the results from the Guo Tao algorithm (GT algorithm). It is shown that the new algorithm (IGT algorithm) provides better results. This preliminarily demonstrates the efficiency of the new algorithm in complicated dynamic environments. 展开更多
关键词 dynamic function optimization Guo Tao algorithm (GT algorithm) benchmark problems
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SW-DDFT: Parallel Optimization of the Dynamical Density Functional Theory Algorithm Based on Sunway Bluelight II Supercomputer
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作者 Xiaoguang Lv Tao Liu +5 位作者 Han Qin Ying Guo Jingshan Pan Dawei Zhao Xiaoming Wu Meihong Yang 《Computers, Materials & Continua》 2025年第7期1417-1436,共20页
The Dynamical Density Functional Theory(DDFT)algorithm,derived by associating classical Density Functional Theory(DFT)with the fundamental Smoluchowski dynamical equation,describes the evolution of inhomo-geneous flui... The Dynamical Density Functional Theory(DDFT)algorithm,derived by associating classical Density Functional Theory(DFT)with the fundamental Smoluchowski dynamical equation,describes the evolution of inhomo-geneous fluid density distributions over time.It plays a significant role in studying the evolution of density distributions over time in inhomogeneous systems.The Sunway Bluelight II supercomputer,as a new generation of China’s developed supercomputer,possesses powerful computational capabilities.Porting and optimizing industrial software on this platform holds significant importance.For the optimization of the DDFT algorithm,based on the Sunway Bluelight II supercomputer and the unique hardware architecture of the SW39000 processor,this work proposes three acceleration strategies to enhance computational efficiency and performance,including direct parallel optimization,local-memory constrained optimization for CPEs,and multi-core groups collaboration and communication optimization.This method combines the characteristics of the program’s algorithm with the unique hardware architecture of the Sunway Bluelight II supercomputer,optimizing the storage and transmission structures to achieve a closer integration of software and hardware.For the first time,this paper presents Sunway-Dynamical Density Functional Theory(SW-DDFT).Experimental results show that SW-DDFT achieves a speedup of 6.67 times within a single-core group compared to the original DDFT implementation,with six core groups(a total of 384 CPEs),the maximum speedup can reach 28.64 times,and parallel efficiency can reach 71%,demonstrating excellent acceleration performance. 展开更多
关键词 Sunway supercomputer high-performance computing dynamical density functional theory parallel optimization
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OSCILLATION OF SECOND-ORDER NEUTRAL DYNAMIC FUNCTIONAL EQUATIONS
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作者 Wu Hongwu Liu Hongji Zhuang Rongkun 《Annals of Differential Equations》 2005年第3期439-442,共4页
In this paper we establish some oscillation criteria for the second-order neutral dynamic delay equations on time scales. By using the generalized Riccati technique, new oscillation criteria are obtained.
关键词 time scale NEUTRAL dynamic functional equations OSCILLATION
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TIME-HARMONIC DYNAMIC GREEN'S FUNCTIONS FOR ONE-DIMENSIONAL HEXAGONAL QUASICRYSTALS 被引量:3
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作者 Wang Xu 《Acta Mechanica Solida Sinica》 SCIE EI 2005年第4期302-306,共5页
Quasicrystals have additional phason degrees of freedom not found in conventional crystals. In this paper, we present an exact solution for time-harmonic dynamic Green's function of one-dimensional hexagonal quasicry... Quasicrystals have additional phason degrees of freedom not found in conventional crystals. In this paper, we present an exact solution for time-harmonic dynamic Green's function of one-dimensional hexagonal quasicrystals with the Laue classes 6/mh and 6/mhmm. Through the introduction of two new functions φ and ψ, the original problem is reduced to the determination of Green's functions for two independent Helmholtz equations. The explicit expressions of displacement and stress fields are presented and their asymptotic behaviors are discussed. The static Green's function can be obtained by letting the circular frequency approach zero. 展开更多
关键词 dynamic Green's function one-dimensional hexagonal quasicrystal Helmholtz equation
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Dynamical correlation functions of the quadratic coupling spin-Boson model
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作者 郑大川 同宁华 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第6期81-86,共6页
The spin-boson model with quadratic coupling is studied using the bosonic numerical renormalization group method.We focus on the dynamical auto-correlation functions CO(ω), with the operator taken as σx, σz, and ... The spin-boson model with quadratic coupling is studied using the bosonic numerical renormalization group method.We focus on the dynamical auto-correlation functions CO(ω), with the operator taken as σx, σz, and X, respectively. In the weak-coupling regime α 〈 αc, these functions show power law ω-dependence in the small frequency limit, with the powers 1 + 2s, 1 + 2s, and s, respectively. At the critical point α = αc of the boson-unstable quantum phase transition, the critical exponents yO of these correlation functions are obtained as yσx= yσz= 1-2s and yX=-s, respectively. Here s is the bath index and X is the boson displacement operator. Close to the spin flip point, the high frequency peak of Cσx(ω) is broadened significantly and the line shape changes qualitatively, showing enhanced dephasing at the spin flip point. 展开更多
关键词 quadratic-coupling spin-boson model numerical renormalization group quantum phase transition dynamical correlation function
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DYNAMIC OBSERVATION OF THYROID FUNCTION IN PATIENTS WITH APLASTIC ANEMIA
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作者 曹庆学 刘建宾 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 1991年第1期52-54,共3页
Accelerating cell growth is one of the functions of thyroid hormone. In the absence or lack of this hormone, hematopoietic disorder may occur. Dynamic observation of thyroid function in aplastic anemia (AA) state has ... Accelerating cell growth is one of the functions of thyroid hormone. In the absence or lack of this hormone, hematopoietic disorder may occur. Dynamic observation of thyroid function in aplastic anemia (AA) state has not been reported yet. 展开更多
关键词 THAN dynamic OBSERVATION OF THYROID function IN PATIENTS WITH APLASTIC ANEMIA
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Structural,Electrical,and Lithium Ion Dynamics of Li2MnO3 from Density Functional Theory
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作者 陈永昌 霍苗 +5 位作者 刘洋 陈桐 冷成财 李强 孙兆林 宋丽娟 《Chinese Physics Letters》 SCIE CAS CSCD 2015年第1期132-136,共5页
The layered Li2MnO3 is investigated by using the first-principles calculations within the GGA and GGA-t-U scheme, respectively. Within the GGA4-U approach, the calculated intercalation voltage (ranges from 4,5 V to 4... The layered Li2MnO3 is investigated by using the first-principles calculations within the GGA and GGA-t-U scheme, respectively. Within the GGA4-U approach, the calculated intercalation voltage (ranges from 4,5 V to 4.9 V) is found to be in good agreement with experiments. From the analysis of electronic structure, the pure phase Li2MnO3 is insulating, which is indicative of poor electronic-conduction properties. However, further studies of lithium ion diffusion in bulk Li2MnO3 show that unlike the two-dimensional diffusion pathways in rock salt structure layered cathode materials, lithium can diffuse in a three-dimensional pathway in Li2MnO3, with moderate lithium migration energy barrier ranges from 0.57 to 0.63 e V. 展开更多
关键词 Li Structural Electrical and Lithium Ion dynamics of Li2MnO3 from Density functional Theory MNO
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Dynamic changes of cellular immune function and individualized adjustments of immunosup-pressant for the management of severe infection after liver transplantation
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作者 李瑞东 《外科研究与新技术》 2011年第4期276-276,共1页
Objective To explore the dynamic changes of the cellular immune function in severe infection after liver transplantation,and to guide the individualized immunology adjustment. Methods 378 cases of liver transplantatio... Objective To explore the dynamic changes of the cellular immune function in severe infection after liver transplantation,and to guide the individualized immunology adjustment. Methods 378 cases of liver transplantation were analyzed retrospectively. Seventy - four cases ( infection group) suffered serious infection,including 54 cases cured ( cure group) ,20 cases died ( 展开更多
关键词 than dynamic changes of cellular immune function and individualized adjustments of immunosup-pressant for the management of severe infection after liver transplantation
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Machine learning-based characterization of dynamic brain functional network connectivity in patients with first-episode schizophrenia
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作者 LIU Pei 《China Medical Abstracts(Internal Medicine)》 2025年第3期190-191,共2页
Objective Using resting-state functional magnetic resonance imaging (rs-fMRI),we explored the changes in dynamic functional network connections (dFNC) in the brains of patients with first-episode schizophrenia (SZ)and... Objective Using resting-state functional magnetic resonance imaging (rs-fMRI),we explored the changes in dynamic functional network connections (dFNC) in the brains of patients with first-episode schizophrenia (SZ)and evaluated the potential clinical value of dFNC changes in combination with a machine learning model. 展开更多
关键词 dynamic brain functional network connectivity resting state functional magnetic resonance imaging dfnc dynamic functional network connections machine learning model machine learning first episode schizophrenia clinical value
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A New Sliding Function for Discrete Predictive Sliding Mode Control of Time Delay Systems 被引量:9
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作者 Abdennebi Nizar Ben Mansour Houda Nouri Ahmed Said 《International Journal of Automation and computing》 EI CSCD 2013年第4期288-295,共8页
The control of time delay systems is still an open area for research. This paper proposes an enhanced model predictive discrete-time sliding mode control with a new sliding function for a linear system with state dela... The control of time delay systems is still an open area for research. This paper proposes an enhanced model predictive discrete-time sliding mode control with a new sliding function for a linear system with state delay. Firstly, a new sliding function including a present value and a past value of the state, called dynamic surface, is designed by means of linear matrix inequalities (LMIs). Then, using this dynamic function and the rolling optimization method in the predictive control strategy, a discrete predictive sliding mode controller is synthesized. This new strategy is proposed to eliminate the undesirable effect of the delay term in the closed loop system. Also, the designed control strategy is more robust, and has a chattering reduction property and a faster convergence of the system s state. Finally, a numerical example is given to illustrate the effectiveness of the proposed control. 展开更多
关键词 State time delay systems discrete sliding mode control model predictive control dynamic sliding function linear matrix inequalities (LMIs) chattering.
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An algorithm for moving target detection in IR image based on grayscale distribution and kernel function 被引量:6
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作者 王鲁平 张路平 +1 位作者 赵明 李飚 《Journal of Central South University》 SCIE EI CAS 2014年第11期4270-4278,共9页
A fast algorithm based on the grayscale distribution of infrared target and the weighted kernel function was proposed for the moving target detection(MTD) in dynamic scene of image series. This algorithm is used to de... A fast algorithm based on the grayscale distribution of infrared target and the weighted kernel function was proposed for the moving target detection(MTD) in dynamic scene of image series. This algorithm is used to deal with issues like the large computational complexity, the fluctuation of grayscale, and the noise in infrared images. Four characteristic points were selected by analyzing the grayscale distribution in infrared image, of which the series was quickly matched with an affine transformation model. The image was then divided into 32×32 squares and the gray-weighted kernel(GWK) for each square was calculated. At last, the MTD was carried out according to the variation of the four GWKs. The results indicate that the MTD can be achieved in real time using the algorithm with the fluctuations of grayscale and noise can be effectively suppressed. The detection probability is greater than 90% with the false alarm rate lower than 5% when the calculation time is less than 40 ms. 展开更多
关键词 moving target detection gray-weighted kernel function dynamic background
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Dynamic anti-plane analysis for two symmetrically interfacial cracks near circular cavity in piezoelectric bi-materials 被引量:5
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作者 A.HASSAN 宋天舒 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2014年第10期1261-1270,共10页
The present paper is exposed theoretically to the influence on the dynamic stress intensity factor (DSIF) in the piezoelectric bi-materials model with two symmet- rically permeable interracial cracks near the edges ... The present paper is exposed theoretically to the influence on the dynamic stress intensity factor (DSIF) in the piezoelectric bi-materials model with two symmet- rically permeable interracial cracks near the edges of a circular cavity, subjected to the dynamic incident anti-plane shearing wave (SH-wave). An available theoretical method to dynamic analysis in the related research field is provided. The formulations are based on Green's function method. The DSIFs at the inner and outer tips of the left crack are obtained by solving the boundary value problems with the conjunction and crack- simulation technique. The numerical results are obtained by the FORTRAN language program and plotted to show the influence of the variations of the physical parameters, the structural geometry, and the wave frequencies of incident wave on the dimensionless DSIFs. Comparisons with previous work and between the inner and outer tips are con- cluded. 展开更多
关键词 symmetrically interfacial crack piezoelectric bi-material Green's function dynamic stress intensity factor (DSIF) dynamic anti-plane shearing wave (SH-wave)
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STUDY ON DYNAMIC STRESS INTENSITY FACTORS OF DISK WITH A RADIAL EDGE CRACK SUBJECTED TO EXTERNAL IMPULSIVE PRESSURE 被引量:1
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作者 Chen Aijun 《Acta Mechanica Solida Sinica》 SCIE EI 2007年第1期41-49,共9页
A dynamic weight function method is presented for dynamic stress intensity factors of circular disk with a radial edge crack under external impulsive pressure. The dynamic stresses in a circular disk are solved under ... A dynamic weight function method is presented for dynamic stress intensity factors of circular disk with a radial edge crack under external impulsive pressure. The dynamic stresses in a circular disk are solved under abrupt step external pressure using the eigenfunction method. The solution consists of a quasi-static solution satisfying inhomogeneous boundary conditions and a dynamic solution satisfying homogeneous boundary conditions. By making use of Fourier- Bessel series expansion, the history and distribution of dynamic stresses in the circular disk are derived. Furthermore, the equation for stress intensity factors under uniform pressure is used as the reference case, the weight function equation for the circular disk containing an edge crack is worked out, and the dynamic stress intensity factor equation for the circular disk containing a radial edge crack can be given. The results indicate that the stress intensity factors under sudden step external pressure vary periodically with time, and the ratio of the maximum value of dynamic stress intensity factors to the corresponding static value is about 2.0. 展开更多
关键词 circular disk cracks dynamic stress intensity factors dynamic weight function Fourier-Bessel series
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Spring-Loaded Inverted Pendulum Hopping via Hybrid Averaging and Control Lyapunov Function 被引量:1
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作者 Hao Sun Junjie Yang +2 位作者 Yinghao Jia Qinghua Li Changhong Wang 《Journal of Bionic Engineering》 SCIE EI CSCD 2023年第1期291-307,共17页
The Spring-Loaded Inverted Pendulum(SLIP)has been regarded as a canonical model for hopping and running dynamics of legged robots.This paper presents a novel control of the actuated-SLIP hopping on unknown terrains.We... The Spring-Loaded Inverted Pendulum(SLIP)has been regarded as a canonical model for hopping and running dynamics of legged robots.This paper presents a novel control of the actuated-SLIP hopping on unknown terrains.We propose that in the neighborhood of the desired stable hybrid limit cycle,the local dynamical behavior of a hybrid system can be expressed by a set of phase coordinates and transverse coordinates.Under some acceptable assumptions,the hybrid averaging theorem is applied on the SLIP non-integrable dynamics to simplify the controller design.Using the inherent symmetry of SLIP dynamics,a control Lyapunov function-based hybrid averaging controller is developed to ensure the exponential stability of the desired gait orbit.This results in a set of linear constraints on the control signal,which can be readily solved by a quadratic programming optimization.Furthermore,a novel method is introduced to improve the robustness against unknown disturbances through the online constraint adjustment.The proposed controller is evaluated in various simulations,demonstrating the SLIP hopping on diverse terrains,including flat,sin-wave,and unregular terrains.The performance of the approach is also validated on a quadruped robot SCIT Dog for generating dynamic gaits such as pronking. 展开更多
关键词 Legged robots-Spring-Loaded Inverted Pendulum Control Lyapunov function dynamic hopping
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Analysis of dynamic stress intensity factors of thick-walled cylinder under internal impulsive pressure 被引量:3
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作者 Aijun Chen Lianfang Liao Dingguo Zhang 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2009年第6期803-809,共7页
Dynamic stress intensity factors are evaluated for thick-walled cylinder with a radial edge crack under internal impulsive pressure. Firstly, the equation for stress intensity factors under static uniform pressure is ... Dynamic stress intensity factors are evaluated for thick-walled cylinder with a radial edge crack under internal impulsive pressure. Firstly, the equation for stress intensity factors under static uniform pressure is used as the reference case, and then the weight function for a thick-walled cylinder containing a radial edge crack can be worked out. Secondly, the dynamic stresses in uncracked thick-walled cylinders are solved under internal impulsive pressure by using mode shape function method. The solution consists of a quasi-static solution satisfying inhomogeneous boundary conditions and a dynamic solution satisfying homogeneous boundary condi- tions, and the history and distribution of dynamic stresses in thick-walled cylinders are derived in terms of Fourier-Bessel series. Finally, the dynamic stress intensity factor equations for thick-walled cylinder containing a radial edge crack sub- jected to internal impulsive pressure are given by dynamic weight function method. The finite element method is utilized to verify the results of numerical examples, showing the validity and feasibility of the proposed method. 展开更多
关键词 Thick-walled cylinder . Cracks .dynamic stress intensity factors . Weight function methodMode shape function
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Equilibrium dynamics of the sub-Ohmic spin-boson model under bias
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作者 郑大川 同宁华 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第6期73-80,共8页
Using the bosonic numerical renormalization group method, we studied the equilibrium dynamical correlation function C(ω) of the spin operator σz for the biased sub-Ohmic spin-boson model. The small-ω behavior C... Using the bosonic numerical renormalization group method, we studied the equilibrium dynamical correlation function C(ω) of the spin operator σz for the biased sub-Ohmic spin-boson model. The small-ω behavior C(ω) ∝ ω~s is found to be universal and independent of the bias ε and the coupling strength α(except at the quantum critical point α = αc and ε = 0). Our NRG data also show C(ω) ∝ χ~2ω~s for a wide range of parameters, including the biased strong coupling regime(ε = 0 and α 〉 αc), supporting the general validity of the Shiba relation. Close to the quantum critical point αc,the dependence of C(ω) on α and ε is understood in terms of the competition between ε and the crossover energy scale ω0^*of the unbiased case. C(ω) is stable with respect to ε for ε《ε^*. For ε 》ε^*, it is suppressed by ε in the low frequency regime. We establish that ε^*∝(ω0^*)^1/θ holds for all sub-Ohmic regime 0≤s 〈 1, with θ = 2/(3s) for 0 〈 s≤1/2 and θ = 2/(1 + s) for 1/2 〈 s 〈 1. The variation of C(ω) with α and ε is summarized into a crossover phase diagram on the α–ε plane. 展开更多
关键词 spin-boson model numerical renormalization group quantum phase transition dynamical correlation function
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Equilibrium dynamics of the sub-ohmic spin-boson model at finite temperature
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作者 Ke Yang Ning-Hua Tong 《Chinese Physics B》 SCIE EI CAS CSCD 2021年第4期159-165,共7页
We use the full-density matrix numerical renormalization group method to calculate the equilibrium dynamical correlation function C(ω) of the spin operator σ_(z) at finite temperature for the sub-ohmic spin-boson mo... We use the full-density matrix numerical renormalization group method to calculate the equilibrium dynamical correlation function C(ω) of the spin operator σ_(z) at finite temperature for the sub-ohmic spin-boson model.A peak is observed at the frequency ω_(T)~T in the curve of C(ω).The curve merges with the zero-temperature C(ω) in ω>>ω_(T) and deviates significantly from the zero-temperature curve in ω<<ω_(T). 展开更多
关键词 spin-boson model full-density matrix renormalization group quantum phase transition dynamical correlation function finite temperature
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