In order to improve the transform efficiency of bi-stable energy harvester（BEH）,this paper proposes an advanced bi-stable energy harvester（ABEH）,which is composed of two bi-stable beams coupling through their magn...In order to improve the transform efficiency of bi-stable energy harvester（BEH）,this paper proposes an advanced bi-stable energy harvester（ABEH）,which is composed of two bi-stable beams coupling through their magnets.Theoretical analyzes and simulations for the ABEH are carried out.First,the mathematical model is established and its dynamical equations are derived.The formulas of magnetic force in two directions are given.The potential energy barrier of ABEH is reduced and the snap-through is liable to occur between potential wells.To demonstrate the ABEH＇s advantage in harvesting energy,comparisons between the ABEH and the BEH are carried out for both harmonic and stochastic excitations.Our results reveal that the ABEH＇s inter-well response can be elicited by a low-frequency excitation and the harvester can attain frequent jumping between potential wells at fairly weak random excitations.Thus,it can generate a higher output power.The present findings prove that the ABEH is preferable in harvesting energy and can be optimally designed such that it attains the best harvesting performance.展开更多
Differing from other subtypes of inhibitory interneuron,chandelier or axo-axonic cells form depolarizing GABAergic synapses exclusively onto the axon initial segment(AIS)of targeted pyramidal cells(PCs).However,the de...Differing from other subtypes of inhibitory interneuron,chandelier or axo-axonic cells form depolarizing GABAergic synapses exclusively onto the axon initial segment(AIS)of targeted pyramidal cells(PCs).However,the debate whether these AIS-GABAergic inputs produce excitation or inhibition in neuronal processing is not resolved.Using realistic NEURON modeling and electrophysiological recording of cortical layer-5 PCs,we quantitatively demonstrate that the onset-timing of AIS-GABAergic input,relative to dendritic excitatory glutamatergic inputs,determines its bi-directional regulation of the efficacy of synaptic integration and spike generation in a PC.More specifically,AIS-GABAergic inputs promote the boosting effect of voltage-activated Na+channels on summed synaptic excitation when they precede glutamatergic inputs by>15 ms,while for nearly concurrent excitatory inputs,they primarily produce a shunting inhibition at the AIS.Thus,our findings offer an integrative mechanism by which AIS-targeting interneurons exert sophisticated regulation of the input-output function in targeted PCs.展开更多
基金Project supported by the National Natural Science Foundation of China(Grant No.11172234)the Scholarship from China Scholarship Council(Grant No.201506290092)
文摘In order to improve the transform efficiency of bi-stable energy harvester（BEH）,this paper proposes an advanced bi-stable energy harvester（ABEH）,which is composed of two bi-stable beams coupling through their magnets.Theoretical analyzes and simulations for the ABEH are carried out.First,the mathematical model is established and its dynamical equations are derived.The formulas of magnetic force in two directions are given.The potential energy barrier of ABEH is reduced and the snap-through is liable to occur between potential wells.To demonstrate the ABEH＇s advantage in harvesting energy,comparisons between the ABEH and the BEH are carried out for both harmonic and stochastic excitations.Our results reveal that the ABEH＇s inter-well response can be elicited by a low-frequency excitation and the harvester can attain frequent jumping between potential wells at fairly weak random excitations.Thus,it can generate a higher output power.The present findings prove that the ABEH is preferable in harvesting energy and can be optimally designed such that it attains the best harvesting performance.
基金supported by the National Natural Science Foundation of China(32130043 and 32071025)the Interdisciplinary Research Fund of Beijing Normal University,China.
文摘Differing from other subtypes of inhibitory interneuron,chandelier or axo-axonic cells form depolarizing GABAergic synapses exclusively onto the axon initial segment(AIS)of targeted pyramidal cells(PCs).However,the debate whether these AIS-GABAergic inputs produce excitation or inhibition in neuronal processing is not resolved.Using realistic NEURON modeling and electrophysiological recording of cortical layer-5 PCs,we quantitatively demonstrate that the onset-timing of AIS-GABAergic input,relative to dendritic excitatory glutamatergic inputs,determines its bi-directional regulation of the efficacy of synaptic integration and spike generation in a PC.More specifically,AIS-GABAergic inputs promote the boosting effect of voltage-activated Na+channels on summed synaptic excitation when they precede glutamatergic inputs by>15 ms,while for nearly concurrent excitatory inputs,they primarily produce a shunting inhibition at the AIS.Thus,our findings offer an integrative mechanism by which AIS-targeting interneurons exert sophisticated regulation of the input-output function in targeted PCs.
