Objective: to investigate the effects of cognitive-motor dual task training on balance function and Activities of daily living (ADL) in stroke patients, so as to improve the quality of life and adaptability of stroke ...Objective: to investigate the effects of cognitive-motor dual task training on balance function and Activities of daily living (ADL) in stroke patients, so as to improve the quality of life and adaptability of stroke patients after returning to community life. Methods: a total of 48 stroke patients who were hospitalized in Beijing Rehabilitation Hospital of Capital Medical University from October 2020 to April 2021 and met the inclusion and exclusion criteria were randomly divided into intervention group (n=24) and control group (n=24). The control group received routine rehabilitation training. The intervention group received cognitive-motor dual task training on the basis of routine rehabilitation training, and the training time and frequency were the same for the two groups. The intervention training lasted for 8 weeks. Changes in patients' balance function and ADL were assessed before and after 8 weeks of intervention, including Berg Balance Scale, Fugl-Meyer Balance Scale and ADL score. Changes in scores of each test were recorded for statistical analysis. Results: after the end of the experiment, intervention group 2 and control group all completed the study 8 weeks after intervention, intervention group and control group showed significant improvement in the three tests compared with before intervention. When standing up while sitting and standing without support, the Berg balance scale score of intervention group was significantly higher than that of control group. Fugl-Meyer and ADL scores of the intervention group under the dual task were significantly higher than those of the control group. After three tests, statistical analysis showed that the differences were statistically significant (P <0.05). Conclusion: the cognitive-motor dual task training can improve the balance function and ADL of stroke patients, and the dual task training combined with the routine rehabilitation training is more conducive to the recovery of balance function of patients, so as to improve the ADL.展开更多
<strong>Objective</strong>: Purpose of this study was to investigate the behavioral and brain activity impairments in patients after moderate traumatic brain injury (mTBI) in comparison with the normal ran...<strong>Objective</strong>: Purpose of this study was to investigate the behavioral and brain activity impairments in patients after moderate traumatic brain injury (mTBI) in comparison with the normal ranges while dual-tasks performing. We would like to evaluate dual-tasking as diagnostic and rehabilitation tool and to test hypothesis of brain aging after mTBI. <strong>Material and Methods</strong>: Electroencephalographic (EEG), stabilographic and clinical study was performed in 11 patients (mean age 28.8 ± 8.4 years) for up to 1 - 12 months after a mTBI in comparison with 17 healthy subjects (26.7 ± 5.1 years). All the participants performed two motor and two cognitive tasks presented separately, and simultaneously (dual-tasking). <strong>Results</strong>: Clinical examination revealed predominantly cognitive deficit in mTBI patients with intact postural control. EEG data demonstrated coherence decrease for slow (delta-theta) rhythms in frontal-temporal areas predominantly for left hemisphere during cognitive tasks performance. In contrast, EEG coherence for slow spectral bands increased in the same areas in healthy volunteers. EEG coherence increased for fast spectral bands—alpha2 and beta, predominantly in right hemisphere while both healthy adults and patients performed motor components of dual tasks. Rehabilitation course with dual tasks, led to a predominant reduction in cognitive deficits, and EEG coherence increases at the frontal-temporal areas of the left hemisphere. <strong>Conclusions</strong>: Dual-tasks may be used as diagnostic tool in patients after mTBI. This approach demonstrates predominant cognitive deficit, and left hemispheric dysfunction in patients similar to elderly persons and support the hypothesis of brain aging after TBI. Pilot studies also suggested rehabilitation effect of dual-tasking in mTBI patients.展开更多
Stuttering is a common neurological deficit and its underlying cognitive mechanisms are a matter of debate, with evidence suggesting abnormal modulation between speech encoding and other cognitive components. Previous...Stuttering is a common neurological deficit and its underlying cognitive mechanisms are a matter of debate, with evidence suggesting abnormal modulation between speech encoding and other cognitive components. Previous studies have mainly used single task experiments to investigate the disturbance of language production. It is unclear whether there is abnormal interaction between the three language tasks （orthographic, phonological and semantic judgment） in stuttering patients. This study used dual tasks and manipulated the stimulus onset asynchrony （SOA） between tasks 1 and 2 and the nature of the second task, including orthographic, phonological, and semantic judgments. The results showed that the performance records of orthographic judgment, phonological judgment, and semantic judgment were significantly reduced between the patient and control groups with short SOA （P 〈 0.05）. However, different patterns of interaction between task 2 and SOA were observed across subject groups： subjects with stuttering were more strongly modulated by SOA when the second task was semantic judgment or phonological judgment （P 〈 0.05）, but not in the orthographic judgment experiment （P 〉 0.05）. These results indicated that the interaction mechanism between semantic processing and phonological encoding might be an underlying cause for stuttering.展开更多
In order to improve the efficiency of tasks processing and reduce the energy consumption of new energy vehicle(NEV), an adaptive dual task offloading decision-making scheme for Internet of vehicles is proposed based o...In order to improve the efficiency of tasks processing and reduce the energy consumption of new energy vehicle(NEV), an adaptive dual task offloading decision-making scheme for Internet of vehicles is proposed based on information-assisted service of road side units(RSUs) and task offloading theory. Taking the roadside parking space recommendation service as the specific application Scenario, the task offloading model is built and a hierarchical self-organizing network model is constructed, which utilizes the computing power sharing among nodes, RSUs and mobile edge computing(MEC) servers. The task scheduling is performed through the adaptive task offloading decision algorithm, which helps to realize the available parking space recommendation service which is energy-saving and environmental-friendly. Compared with these traditional task offloading decisions, the proposed scheme takes less time and less energy in the whole process of tasks. Simulation results testified the effectiveness of the proposed scheme.展开更多
Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health even...Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health events and falls. Consequently, multi-task training paradigms that simultaneously address both mobility and cognition benefit healthy ageing are important to consider in rehabilitation as well as primary prevention. Objectives: An exploratory RCT is being conducted to: a) describe the feasibility and acceptability of the study design and process, procedures, resources and management in two game-based dual-task training programs delivered in the community;b) to explore the lived experiences of the study participants who completed their respective exercise programs. A secondary objective is to obtain preliminary data on the therapeutic effectiveness of the two dual-task training programs. Methods: Thirty healthy older community dwelling participants aged 70 - 85 with previous history of falls will be recruited and randomized to either dual- task treadmill walking (experimental group) or dual-task recumbent bicycle (control group). Data analysis: The qualitative data will be analyzed by two investigators using a content analysis approach. For the quantitative data, outcome measures will be collected pre and post intervention and included measures to assess core balance, spatial-temporal gait variables, visual tracking and cognitive function, as well as, balance and gait analysis under dual-task conditions. Discussion: This research will demonstrate the feasibility of the dual-task training programs in the community, and demonstrate the system’s ability to improve targeted and integrated (dual-task) aspects of balance, mobility, gaze, and cognitive performance. A blended analysis of balance, mobility gaze and cognition will also contribute to a better understanding of the functional consequences of decline in physical and mental skills with age. Trial registration: This pilot clinical trial has been registered at ClinicalTrials.gov Protocol Registration System: NCT01940055.展开更多
目的基于背侧注意网络(dorsal attention network,DAN)和默认网络(default network,DN)两个与注意力相关脑网络,探讨多焦点经颅直流电刺激(transcranial direct current stimulation,tDCS)能否改善健康老年人在双任务姿势控制中的表现...目的基于背侧注意网络(dorsal attention network,DAN)和默认网络(default network,DN)两个与注意力相关脑网络,探讨多焦点经颅直流电刺激(transcranial direct current stimulation,tDCS)能否改善健康老年人在双任务姿势控制中的表现。方法22名健康老年人被随机分配接受tDCS和假刺激,两次刺激间隔至少1周。tDCS方案旨在促进DAN的兴奋性并抑制DN的兴奋性,刺激时长为20 min(DAN+/DN-tDCS);假刺激方案仅持续1 min(刺激开始和结束各30 s)。在每次干预前后,使用测力台采集受试者在睁眼和闭眼条件下进行单、双任务姿势控制测试的压力中心数据。采用双因素重复测量(刺激方案×刺激前后)方差分析评估刺激方案对受试者各姿势控制指标的影响。结果所有受试者均完成实验,未出现明显不良反应。在睁眼双任务中,摆动合速度(F=5.72,P=0.021)和前后方向摆动速度(F=5.085,P=0.029)均存在显著交互作用。在DAN+/DN-tDCS干预后,前后方向摆动速度(P=0.019)和摆动合速度(P=0.01)均显著下降。睁眼条件下,摆动面积双任务消耗(F=8.727,P=0.005)也存在显著交互作用。在DAN+/DN-tDCS干预后摆动面积双任务消耗降低(P=0.038),而假刺激干预后摆动面积双任务消耗反而增加(P=0.049)。结论DAN+/DN-tDCS干预能显著改善健康老年人在双任务姿势控制中的表现(降低摆动速度、面积及双任务消耗),提示该刺激方案具有提升老年人在双任务条件下姿势控制稳定性的潜力。展开更多
目的:探讨运动-认知双重任务训练对脑卒中偏瘫患者认知及运动功能的疗效。方法:收集26例脑卒中偏瘫患者,随机分为运动-认知双重任务训练(motor-cognitive dual-task training,MCDT)组和序贯运动-认知任务训练(mixed motor and cognitive...目的:探讨运动-认知双重任务训练对脑卒中偏瘫患者认知及运动功能的疗效。方法:收集26例脑卒中偏瘫患者,随机分为运动-认知双重任务训练(motor-cognitive dual-task training,MCDT)组和序贯运动-认知任务训练(mixed motor and cognitive training,MixT)组,每组各13例。MCDT组在运动训练的同时进行计算任务,而MixT组先进行运动训练,再进行计算任务,每次40 min,每周5次,持续4周。分别在干预前和干预4周后对2组患者进行蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)、起立行走计时(Timed up and Go,TUG)、多方向性伸展测试(Multi-Directional Reach Test,MDRT)、各项步态参数以及简化Fugl-Meyer下肢运动功能量表(Fugl-Meyer assessment scale for lower extremity,FMA-LE)评估。结果:治疗前,2组患者的MoCA、TUG、MDRT、各项步态参数以及FMA-LE差异均无统计学意义(P>0.05)。训练4周后,MCDT组和MixT组的MoCA、TUG、MDRT结果及各项步态参数、FMA-LE评分均较训练前提高(P<0.05),同时,MCDT组训练前后的各项指标之差较MixT组有改善(P<0.05)。结论:运动-认知双重任务能更有效地提高脑卒中偏瘫患者的认知和运动功能。展开更多
文摘Objective: to investigate the effects of cognitive-motor dual task training on balance function and Activities of daily living (ADL) in stroke patients, so as to improve the quality of life and adaptability of stroke patients after returning to community life. Methods: a total of 48 stroke patients who were hospitalized in Beijing Rehabilitation Hospital of Capital Medical University from October 2020 to April 2021 and met the inclusion and exclusion criteria were randomly divided into intervention group (n=24) and control group (n=24). The control group received routine rehabilitation training. The intervention group received cognitive-motor dual task training on the basis of routine rehabilitation training, and the training time and frequency were the same for the two groups. The intervention training lasted for 8 weeks. Changes in patients' balance function and ADL were assessed before and after 8 weeks of intervention, including Berg Balance Scale, Fugl-Meyer Balance Scale and ADL score. Changes in scores of each test were recorded for statistical analysis. Results: after the end of the experiment, intervention group 2 and control group all completed the study 8 weeks after intervention, intervention group and control group showed significant improvement in the three tests compared with before intervention. When standing up while sitting and standing without support, the Berg balance scale score of intervention group was significantly higher than that of control group. Fugl-Meyer and ADL scores of the intervention group under the dual task were significantly higher than those of the control group. After three tests, statistical analysis showed that the differences were statistically significant (P <0.05). Conclusion: the cognitive-motor dual task training can improve the balance function and ADL of stroke patients, and the dual task training combined with the routine rehabilitation training is more conducive to the recovery of balance function of patients, so as to improve the ADL.
文摘<strong>Objective</strong>: Purpose of this study was to investigate the behavioral and brain activity impairments in patients after moderate traumatic brain injury (mTBI) in comparison with the normal ranges while dual-tasks performing. We would like to evaluate dual-tasking as diagnostic and rehabilitation tool and to test hypothesis of brain aging after mTBI. <strong>Material and Methods</strong>: Electroencephalographic (EEG), stabilographic and clinical study was performed in 11 patients (mean age 28.8 ± 8.4 years) for up to 1 - 12 months after a mTBI in comparison with 17 healthy subjects (26.7 ± 5.1 years). All the participants performed two motor and two cognitive tasks presented separately, and simultaneously (dual-tasking). <strong>Results</strong>: Clinical examination revealed predominantly cognitive deficit in mTBI patients with intact postural control. EEG data demonstrated coherence decrease for slow (delta-theta) rhythms in frontal-temporal areas predominantly for left hemisphere during cognitive tasks performance. In contrast, EEG coherence for slow spectral bands increased in the same areas in healthy volunteers. EEG coherence increased for fast spectral bands—alpha2 and beta, predominantly in right hemisphere while both healthy adults and patients performed motor components of dual tasks. Rehabilitation course with dual tasks, led to a predominant reduction in cognitive deficits, and EEG coherence increases at the frontal-temporal areas of the left hemisphere. <strong>Conclusions</strong>: Dual-tasks may be used as diagnostic tool in patients after mTBI. This approach demonstrates predominant cognitive deficit, and left hemispheric dysfunction in patients similar to elderly persons and support the hypothesis of brain aging after TBI. Pilot studies also suggested rehabilitation effect of dual-tasking in mTBI patients.
基金the China Postdoctoral Science Foundation,No.2001,#14the Capital Medical Development Science Research Program,No.2005-2003
文摘Stuttering is a common neurological deficit and its underlying cognitive mechanisms are a matter of debate, with evidence suggesting abnormal modulation between speech encoding and other cognitive components. Previous studies have mainly used single task experiments to investigate the disturbance of language production. It is unclear whether there is abnormal interaction between the three language tasks （orthographic, phonological and semantic judgment） in stuttering patients. This study used dual tasks and manipulated the stimulus onset asynchrony （SOA） between tasks 1 and 2 and the nature of the second task, including orthographic, phonological, and semantic judgments. The results showed that the performance records of orthographic judgment, phonological judgment, and semantic judgment were significantly reduced between the patient and control groups with short SOA （P 〈 0.05）. However, different patterns of interaction between task 2 and SOA were observed across subject groups： subjects with stuttering were more strongly modulated by SOA when the second task was semantic judgment or phonological judgment （P 〈 0.05）, but not in the orthographic judgment experiment （P 〉 0.05）. These results indicated that the interaction mechanism between semantic processing and phonological encoding might be an underlying cause for stuttering.
基金supported by the Scientific Research Project of Henan Province(182102110333)the Doctoral Support Research Project of Henan Polytechnic University(B2012050)the Funding Project for the Young Backbone Teachers of Higher Education Institutions in Henan Province(2019GGJS061)。
文摘In order to improve the efficiency of tasks processing and reduce the energy consumption of new energy vehicle(NEV), an adaptive dual task offloading decision-making scheme for Internet of vehicles is proposed based on information-assisted service of road side units(RSUs) and task offloading theory. Taking the roadside parking space recommendation service as the specific application Scenario, the task offloading model is built and a hierarchical self-organizing network model is constructed, which utilizes the computing power sharing among nodes, RSUs and mobile edge computing(MEC) servers. The task scheduling is performed through the adaptive task offloading decision algorithm, which helps to realize the available parking space recommendation service which is energy-saving and environmental-friendly. Compared with these traditional task offloading decisions, the proposed scheme takes less time and less energy in the whole process of tasks. Simulation results testified the effectiveness of the proposed scheme.
文摘Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health events and falls. Consequently, multi-task training paradigms that simultaneously address both mobility and cognition benefit healthy ageing are important to consider in rehabilitation as well as primary prevention. Objectives: An exploratory RCT is being conducted to: a) describe the feasibility and acceptability of the study design and process, procedures, resources and management in two game-based dual-task training programs delivered in the community;b) to explore the lived experiences of the study participants who completed their respective exercise programs. A secondary objective is to obtain preliminary data on the therapeutic effectiveness of the two dual-task training programs. Methods: Thirty healthy older community dwelling participants aged 70 - 85 with previous history of falls will be recruited and randomized to either dual- task treadmill walking (experimental group) or dual-task recumbent bicycle (control group). Data analysis: The qualitative data will be analyzed by two investigators using a content analysis approach. For the quantitative data, outcome measures will be collected pre and post intervention and included measures to assess core balance, spatial-temporal gait variables, visual tracking and cognitive function, as well as, balance and gait analysis under dual-task conditions. Discussion: This research will demonstrate the feasibility of the dual-task training programs in the community, and demonstrate the system’s ability to improve targeted and integrated (dual-task) aspects of balance, mobility, gaze, and cognitive performance. A blended analysis of balance, mobility gaze and cognition will also contribute to a better understanding of the functional consequences of decline in physical and mental skills with age. Trial registration: This pilot clinical trial has been registered at ClinicalTrials.gov Protocol Registration System: NCT01940055.
文摘目的基于背侧注意网络(dorsal attention network,DAN)和默认网络(default network,DN)两个与注意力相关脑网络,探讨多焦点经颅直流电刺激(transcranial direct current stimulation,tDCS)能否改善健康老年人在双任务姿势控制中的表现。方法22名健康老年人被随机分配接受tDCS和假刺激,两次刺激间隔至少1周。tDCS方案旨在促进DAN的兴奋性并抑制DN的兴奋性,刺激时长为20 min(DAN+/DN-tDCS);假刺激方案仅持续1 min(刺激开始和结束各30 s)。在每次干预前后,使用测力台采集受试者在睁眼和闭眼条件下进行单、双任务姿势控制测试的压力中心数据。采用双因素重复测量(刺激方案×刺激前后)方差分析评估刺激方案对受试者各姿势控制指标的影响。结果所有受试者均完成实验,未出现明显不良反应。在睁眼双任务中,摆动合速度(F=5.72,P=0.021)和前后方向摆动速度(F=5.085,P=0.029)均存在显著交互作用。在DAN+/DN-tDCS干预后,前后方向摆动速度(P=0.019)和摆动合速度(P=0.01)均显著下降。睁眼条件下,摆动面积双任务消耗(F=8.727,P=0.005)也存在显著交互作用。在DAN+/DN-tDCS干预后摆动面积双任务消耗降低(P=0.038),而假刺激干预后摆动面积双任务消耗反而增加(P=0.049)。结论DAN+/DN-tDCS干预能显著改善健康老年人在双任务姿势控制中的表现(降低摆动速度、面积及双任务消耗),提示该刺激方案具有提升老年人在双任务条件下姿势控制稳定性的潜力。
文摘目的:探讨运动-认知双重任务训练对脑卒中偏瘫患者认知及运动功能的疗效。方法:收集26例脑卒中偏瘫患者,随机分为运动-认知双重任务训练(motor-cognitive dual-task training,MCDT)组和序贯运动-认知任务训练(mixed motor and cognitive training,MixT)组,每组各13例。MCDT组在运动训练的同时进行计算任务,而MixT组先进行运动训练,再进行计算任务,每次40 min,每周5次,持续4周。分别在干预前和干预4周后对2组患者进行蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)、起立行走计时(Timed up and Go,TUG)、多方向性伸展测试(Multi-Directional Reach Test,MDRT)、各项步态参数以及简化Fugl-Meyer下肢运动功能量表(Fugl-Meyer assessment scale for lower extremity,FMA-LE)评估。结果:治疗前,2组患者的MoCA、TUG、MDRT、各项步态参数以及FMA-LE差异均无统计学意义(P>0.05)。训练4周后,MCDT组和MixT组的MoCA、TUG、MDRT结果及各项步态参数、FMA-LE评分均较训练前提高(P<0.05),同时,MCDT组训练前后的各项指标之差较MixT组有改善(P<0.05)。结论:运动-认知双重任务能更有效地提高脑卒中偏瘫患者的认知和运动功能。
