Objective: to investigate the effects of cognitive-motor dual task training on balance function and Activities of daily living (ADL) in stroke patients, so as to improve the quality of life and adaptability of stroke ...Objective: to investigate the effects of cognitive-motor dual task training on balance function and Activities of daily living (ADL) in stroke patients, so as to improve the quality of life and adaptability of stroke patients after returning to community life. Methods: a total of 48 stroke patients who were hospitalized in Beijing Rehabilitation Hospital of Capital Medical University from October 2020 to April 2021 and met the inclusion and exclusion criteria were randomly divided into intervention group (n=24) and control group (n=24). The control group received routine rehabilitation training. The intervention group received cognitive-motor dual task training on the basis of routine rehabilitation training, and the training time and frequency were the same for the two groups. The intervention training lasted for 8 weeks. Changes in patients' balance function and ADL were assessed before and after 8 weeks of intervention, including Berg Balance Scale, Fugl-Meyer Balance Scale and ADL score. Changes in scores of each test were recorded for statistical analysis. Results: after the end of the experiment, intervention group 2 and control group all completed the study 8 weeks after intervention, intervention group and control group showed significant improvement in the three tests compared with before intervention. When standing up while sitting and standing without support, the Berg balance scale score of intervention group was significantly higher than that of control group. Fugl-Meyer and ADL scores of the intervention group under the dual task were significantly higher than those of the control group. After three tests, statistical analysis showed that the differences were statistically significant (P <0.05). Conclusion: the cognitive-motor dual task training can improve the balance function and ADL of stroke patients, and the dual task training combined with the routine rehabilitation training is more conducive to the recovery of balance function of patients, so as to improve the ADL.展开更多
<strong>Objective</strong>: Purpose of this study was to investigate the behavioral and brain activity impairments in patients after moderate traumatic brain injury (mTBI) in comparison with the normal ran...<strong>Objective</strong>: Purpose of this study was to investigate the behavioral and brain activity impairments in patients after moderate traumatic brain injury (mTBI) in comparison with the normal ranges while dual-tasks performing. We would like to evaluate dual-tasking as diagnostic and rehabilitation tool and to test hypothesis of brain aging after mTBI. <strong>Material and Methods</strong>: Electroencephalographic (EEG), stabilographic and clinical study was performed in 11 patients (mean age 28.8 ± 8.4 years) for up to 1 - 12 months after a mTBI in comparison with 17 healthy subjects (26.7 ± 5.1 years). All the participants performed two motor and two cognitive tasks presented separately, and simultaneously (dual-tasking). <strong>Results</strong>: Clinical examination revealed predominantly cognitive deficit in mTBI patients with intact postural control. EEG data demonstrated coherence decrease for slow (delta-theta) rhythms in frontal-temporal areas predominantly for left hemisphere during cognitive tasks performance. In contrast, EEG coherence for slow spectral bands increased in the same areas in healthy volunteers. EEG coherence increased for fast spectral bands—alpha2 and beta, predominantly in right hemisphere while both healthy adults and patients performed motor components of dual tasks. Rehabilitation course with dual tasks, led to a predominant reduction in cognitive deficits, and EEG coherence increases at the frontal-temporal areas of the left hemisphere. <strong>Conclusions</strong>: Dual-tasks may be used as diagnostic tool in patients after mTBI. This approach demonstrates predominant cognitive deficit, and left hemispheric dysfunction in patients similar to elderly persons and support the hypothesis of brain aging after TBI. Pilot studies also suggested rehabilitation effect of dual-tasking in mTBI patients.展开更多
Stuttering is a common neurological deficit and its underlying cognitive mechanisms are a matter of debate, with evidence suggesting abnormal modulation between speech encoding and other cognitive components. Previous...Stuttering is a common neurological deficit and its underlying cognitive mechanisms are a matter of debate, with evidence suggesting abnormal modulation between speech encoding and other cognitive components. Previous studies have mainly used single task experiments to investigate the disturbance of language production. It is unclear whether there is abnormal interaction between the three language tasks （orthographic, phonological and semantic judgment） in stuttering patients. This study used dual tasks and manipulated the stimulus onset asynchrony （SOA） between tasks 1 and 2 and the nature of the second task, including orthographic, phonological, and semantic judgments. The results showed that the performance records of orthographic judgment, phonological judgment, and semantic judgment were significantly reduced between the patient and control groups with short SOA （P 〈 0.05）. However, different patterns of interaction between task 2 and SOA were observed across subject groups： subjects with stuttering were more strongly modulated by SOA when the second task was semantic judgment or phonological judgment （P 〈 0.05）, but not in the orthographic judgment experiment （P 〉 0.05）. These results indicated that the interaction mechanism between semantic processing and phonological encoding might be an underlying cause for stuttering.展开更多
In order to improve the efficiency of tasks processing and reduce the energy consumption of new energy vehicle(NEV), an adaptive dual task offloading decision-making scheme for Internet of vehicles is proposed based o...In order to improve the efficiency of tasks processing and reduce the energy consumption of new energy vehicle(NEV), an adaptive dual task offloading decision-making scheme for Internet of vehicles is proposed based on information-assisted service of road side units(RSUs) and task offloading theory. Taking the roadside parking space recommendation service as the specific application Scenario, the task offloading model is built and a hierarchical self-organizing network model is constructed, which utilizes the computing power sharing among nodes, RSUs and mobile edge computing(MEC) servers. The task scheduling is performed through the adaptive task offloading decision algorithm, which helps to realize the available parking space recommendation service which is energy-saving and environmental-friendly. Compared with these traditional task offloading decisions, the proposed scheme takes less time and less energy in the whole process of tasks. Simulation results testified the effectiveness of the proposed scheme.展开更多
Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health even...Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health events and falls. Consequently, multi-task training paradigms that simultaneously address both mobility and cognition benefit healthy ageing are important to consider in rehabilitation as well as primary prevention. Objectives: An exploratory RCT is being conducted to: a) describe the feasibility and acceptability of the study design and process, procedures, resources and management in two game-based dual-task training programs delivered in the community;b) to explore the lived experiences of the study participants who completed their respective exercise programs. A secondary objective is to obtain preliminary data on the therapeutic effectiveness of the two dual-task training programs. Methods: Thirty healthy older community dwelling participants aged 70 - 85 with previous history of falls will be recruited and randomized to either dual- task treadmill walking (experimental group) or dual-task recumbent bicycle (control group). Data analysis: The qualitative data will be analyzed by two investigators using a content analysis approach. For the quantitative data, outcome measures will be collected pre and post intervention and included measures to assess core balance, spatial-temporal gait variables, visual tracking and cognitive function, as well as, balance and gait analysis under dual-task conditions. Discussion: This research will demonstrate the feasibility of the dual-task training programs in the community, and demonstrate the system’s ability to improve targeted and integrated (dual-task) aspects of balance, mobility, gaze, and cognitive performance. A blended analysis of balance, mobility gaze and cognition will also contribute to a better understanding of the functional consequences of decline in physical and mental skills with age. Trial registration: This pilot clinical trial has been registered at ClinicalTrials.gov Protocol Registration System: NCT01940055.展开更多
目的探究不同类型(认知/运动)与负荷(简单/困难)双任务步行对人体前额叶皮层激活特征及行走稳定性的影响。方法采用功能性近红外光谱(functional near infrared spectroscopy,fNIRS)技术和三维动态捕捉系统同时测量33名健康成年人单任...目的探究不同类型(认知/运动)与负荷(简单/困难)双任务步行对人体前额叶皮层激活特征及行走稳定性的影响。方法采用功能性近红外光谱(functional near infrared spectroscopy,fNIRS)技术和三维动态捕捉系统同时测量33名健康成年人单任务步行、简单/困难认知双任务步行、运动双任务步行条件下人体前额叶皮层的氧合血红蛋白浓度和运动学参数,并基于运动学数据间接计算动态稳度(margin of stability,MOS)。结果右背外侧前额叶皮质在困难认知双任务步行激活程度高于困难运动双任务步行(F=7.067,P=0.012);左背外侧前额叶皮质在困难认知双任务步行中的激活程度也高于困难运动双任务步行(F=4.831,P=0.035)。此外,右额极区(P=0.029)、右眶额皮质(P=0.046)、左腹外侧前额叶皮质(P=0.039)、左额极区(P=0.022)认知双任务步行中的激活程度均显著高于运动双任务步行。简单认知双任务行走时MOS_(ap)小于困难认知双任务行走(F=13.357,P=0.001);困难认知双任务行走MOS_(ap)大于困难运动双任务行走(F=8.571,P=0.006);简单认知双任务行走时MOS_(ml)小于困难认知双任务行走(F=5.394,P=0.027);困难认知双任务行走时MOS_(ml)大于困难运动双任务行走(F=4.703,P=0.038)。结论双任务执行涉及前额叶亚区的层级化协同调控机制,其中背外侧前额叶皮层优先协调高阶认知任务的资源分配。不同类型与负荷双任务对前额叶皮层激活及行走稳定性的影响存在交互效应。认知双任务步行时多个前额叶亚区的神经激活强度高于运动双任务;困难认知任务在引发前额叶皮层高激活的同时,伴随行走稳定性的下降。简单认知双任务行走稳定性优于困难认知双任务行走,而困难运动双任务行走稳定性优于困难认知双任务行走。展开更多
文摘Objective: to investigate the effects of cognitive-motor dual task training on balance function and Activities of daily living (ADL) in stroke patients, so as to improve the quality of life and adaptability of stroke patients after returning to community life. Methods: a total of 48 stroke patients who were hospitalized in Beijing Rehabilitation Hospital of Capital Medical University from October 2020 to April 2021 and met the inclusion and exclusion criteria were randomly divided into intervention group (n=24) and control group (n=24). The control group received routine rehabilitation training. The intervention group received cognitive-motor dual task training on the basis of routine rehabilitation training, and the training time and frequency were the same for the two groups. The intervention training lasted for 8 weeks. Changes in patients' balance function and ADL were assessed before and after 8 weeks of intervention, including Berg Balance Scale, Fugl-Meyer Balance Scale and ADL score. Changes in scores of each test were recorded for statistical analysis. Results: after the end of the experiment, intervention group 2 and control group all completed the study 8 weeks after intervention, intervention group and control group showed significant improvement in the three tests compared with before intervention. When standing up while sitting and standing without support, the Berg balance scale score of intervention group was significantly higher than that of control group. Fugl-Meyer and ADL scores of the intervention group under the dual task were significantly higher than those of the control group. After three tests, statistical analysis showed that the differences were statistically significant (P <0.05). Conclusion: the cognitive-motor dual task training can improve the balance function and ADL of stroke patients, and the dual task training combined with the routine rehabilitation training is more conducive to the recovery of balance function of patients, so as to improve the ADL.
文摘<strong>Objective</strong>: Purpose of this study was to investigate the behavioral and brain activity impairments in patients after moderate traumatic brain injury (mTBI) in comparison with the normal ranges while dual-tasks performing. We would like to evaluate dual-tasking as diagnostic and rehabilitation tool and to test hypothesis of brain aging after mTBI. <strong>Material and Methods</strong>: Electroencephalographic (EEG), stabilographic and clinical study was performed in 11 patients (mean age 28.8 ± 8.4 years) for up to 1 - 12 months after a mTBI in comparison with 17 healthy subjects (26.7 ± 5.1 years). All the participants performed two motor and two cognitive tasks presented separately, and simultaneously (dual-tasking). <strong>Results</strong>: Clinical examination revealed predominantly cognitive deficit in mTBI patients with intact postural control. EEG data demonstrated coherence decrease for slow (delta-theta) rhythms in frontal-temporal areas predominantly for left hemisphere during cognitive tasks performance. In contrast, EEG coherence for slow spectral bands increased in the same areas in healthy volunteers. EEG coherence increased for fast spectral bands—alpha2 and beta, predominantly in right hemisphere while both healthy adults and patients performed motor components of dual tasks. Rehabilitation course with dual tasks, led to a predominant reduction in cognitive deficits, and EEG coherence increases at the frontal-temporal areas of the left hemisphere. <strong>Conclusions</strong>: Dual-tasks may be used as diagnostic tool in patients after mTBI. This approach demonstrates predominant cognitive deficit, and left hemispheric dysfunction in patients similar to elderly persons and support the hypothesis of brain aging after TBI. Pilot studies also suggested rehabilitation effect of dual-tasking in mTBI patients.
基金the China Postdoctoral Science Foundation,No.2001,#14the Capital Medical Development Science Research Program,No.2005-2003
文摘Stuttering is a common neurological deficit and its underlying cognitive mechanisms are a matter of debate, with evidence suggesting abnormal modulation between speech encoding and other cognitive components. Previous studies have mainly used single task experiments to investigate the disturbance of language production. It is unclear whether there is abnormal interaction between the three language tasks （orthographic, phonological and semantic judgment） in stuttering patients. This study used dual tasks and manipulated the stimulus onset asynchrony （SOA） between tasks 1 and 2 and the nature of the second task, including orthographic, phonological, and semantic judgments. The results showed that the performance records of orthographic judgment, phonological judgment, and semantic judgment were significantly reduced between the patient and control groups with short SOA （P 〈 0.05）. However, different patterns of interaction between task 2 and SOA were observed across subject groups： subjects with stuttering were more strongly modulated by SOA when the second task was semantic judgment or phonological judgment （P 〈 0.05）, but not in the orthographic judgment experiment （P 〉 0.05）. These results indicated that the interaction mechanism between semantic processing and phonological encoding might be an underlying cause for stuttering.
基金supported by the Scientific Research Project of Henan Province(182102110333)the Doctoral Support Research Project of Henan Polytechnic University(B2012050)the Funding Project for the Young Backbone Teachers of Higher Education Institutions in Henan Province(2019GGJS061)。
文摘In order to improve the efficiency of tasks processing and reduce the energy consumption of new energy vehicle(NEV), an adaptive dual task offloading decision-making scheme for Internet of vehicles is proposed based on information-assisted service of road side units(RSUs) and task offloading theory. Taking the roadside parking space recommendation service as the specific application Scenario, the task offloading model is built and a hierarchical self-organizing network model is constructed, which utilizes the computing power sharing among nodes, RSUs and mobile edge computing(MEC) servers. The task scheduling is performed through the adaptive task offloading decision algorithm, which helps to realize the available parking space recommendation service which is energy-saving and environmental-friendly. Compared with these traditional task offloading decisions, the proposed scheme takes less time and less energy in the whole process of tasks. Simulation results testified the effectiveness of the proposed scheme.
文摘Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health events and falls. Consequently, multi-task training paradigms that simultaneously address both mobility and cognition benefit healthy ageing are important to consider in rehabilitation as well as primary prevention. Objectives: An exploratory RCT is being conducted to: a) describe the feasibility and acceptability of the study design and process, procedures, resources and management in two game-based dual-task training programs delivered in the community;b) to explore the lived experiences of the study participants who completed their respective exercise programs. A secondary objective is to obtain preliminary data on the therapeutic effectiveness of the two dual-task training programs. Methods: Thirty healthy older community dwelling participants aged 70 - 85 with previous history of falls will be recruited and randomized to either dual- task treadmill walking (experimental group) or dual-task recumbent bicycle (control group). Data analysis: The qualitative data will be analyzed by two investigators using a content analysis approach. For the quantitative data, outcome measures will be collected pre and post intervention and included measures to assess core balance, spatial-temporal gait variables, visual tracking and cognitive function, as well as, balance and gait analysis under dual-task conditions. Discussion: This research will demonstrate the feasibility of the dual-task training programs in the community, and demonstrate the system’s ability to improve targeted and integrated (dual-task) aspects of balance, mobility, gaze, and cognitive performance. A blended analysis of balance, mobility gaze and cognition will also contribute to a better understanding of the functional consequences of decline in physical and mental skills with age. Trial registration: This pilot clinical trial has been registered at ClinicalTrials.gov Protocol Registration System: NCT01940055.
文摘目的探究不同类型(认知/运动)与负荷(简单/困难)双任务步行对人体前额叶皮层激活特征及行走稳定性的影响。方法采用功能性近红外光谱(functional near infrared spectroscopy,fNIRS)技术和三维动态捕捉系统同时测量33名健康成年人单任务步行、简单/困难认知双任务步行、运动双任务步行条件下人体前额叶皮层的氧合血红蛋白浓度和运动学参数,并基于运动学数据间接计算动态稳度(margin of stability,MOS)。结果右背外侧前额叶皮质在困难认知双任务步行激活程度高于困难运动双任务步行(F=7.067,P=0.012);左背外侧前额叶皮质在困难认知双任务步行中的激活程度也高于困难运动双任务步行(F=4.831,P=0.035)。此外,右额极区(P=0.029)、右眶额皮质(P=0.046)、左腹外侧前额叶皮质(P=0.039)、左额极区(P=0.022)认知双任务步行中的激活程度均显著高于运动双任务步行。简单认知双任务行走时MOS_(ap)小于困难认知双任务行走(F=13.357,P=0.001);困难认知双任务行走MOS_(ap)大于困难运动双任务行走(F=8.571,P=0.006);简单认知双任务行走时MOS_(ml)小于困难认知双任务行走(F=5.394,P=0.027);困难认知双任务行走时MOS_(ml)大于困难运动双任务行走(F=4.703,P=0.038)。结论双任务执行涉及前额叶亚区的层级化协同调控机制,其中背外侧前额叶皮层优先协调高阶认知任务的资源分配。不同类型与负荷双任务对前额叶皮层激活及行走稳定性的影响存在交互效应。认知双任务步行时多个前额叶亚区的神经激活强度高于运动双任务;困难认知任务在引发前额叶皮层高激活的同时,伴随行走稳定性的下降。简单认知双任务行走稳定性优于困难认知双任务行走,而困难运动双任务行走稳定性优于困难认知双任务行走。
