Dry-coating electrode fabrication technologies have emerged as a promising solution for green and low-cost battery manufacturing,which can eliminate the use of contaminative and toxic solvents that challenge current b...Dry-coating electrode fabrication technologies have emerged as a promising solution for green and low-cost battery manufacturing,which can eliminate the use of contaminative and toxic solvents that challenge current battery industry.The key challenges of current dry-coating electrode fabrication lie in the uneven dispersion of various components and limited scalability.In this review,we introduce the fundamental mechanisms and recent advances in dry-coating electrode fabrication technologies,with a focus on key strategies for material design and process optimization that can promote structural integrity and electrochemical performance of the dry-coating electrodes.We also discuss the effectiveness of these innovative approaches towards promoted processing and scalability.In addition,several solutions regarding inorganic additives,composite binders,and lowmelting-point additives are further introduced,which shows promise to address the component agglomeration and interface adhesion.Moreover,we prospect the deployment of dry-coating electrode fabrication technologies in solid-state batteries and conversion-type batteries,where the solvent-free nature and interfacial compatibility offer appealing benefits.The current challenges and future opportunities for dry-coating electrode fabrication technologies are summarized,aiming to provide valuable insights to this emerging field.展开更多
The properties of dry-coated paracetamol particles(fast-dissolving model drug)with carnauba wax particles as the coating agent(dissolution retardant)were investigated.Raman mapping technique was used to non-destructiv...The properties of dry-coated paracetamol particles(fast-dissolving model drug)with carnauba wax particles as the coating agent(dissolution retardant)were investigated.Raman mapping technique was used to non-destructively examine the thickness and homogeneity of coated particles.The results showed that the wax existed in two forms on the surface of the paracetamol particles,forming a porous coating layer:i)whole wax particles on the surface of paracetamol and glued together with other wax surface particles,and ii)deformed wax particles spread on the surface.Regardless of the final particle size fraction(between 100 and 800 mm),the coating thickness had high variability,with average thickness of 5.9±4.2 mm.The ability of carnauba wax to decrease the dissolution rate of paracetamol was confirmed by dissolution of powder and tablet formulations.The dissolution was slower for larger coated particles.Tableting further reduced the dissolution rate,clearly indicating the impact of subsequent formulation processes on the final quality of the product.展开更多
A novel statistical approach to evaluate the manufacturing quality of press coated tablets in terms of the centering of their core is presented. We also provide a formula to determine the necessary sample size. This a...A novel statistical approach to evaluate the manufacturing quality of press coated tablets in terms of the centering of their core is presented. We also provide a formula to determine the necessary sample size. This approach is applied to real data.展开更多
基金supported by the National Natural Science Foundation of China (22575145,22209108,52503273)the Fundamental Research Funds for the Central Universities (24X010301678)the Natural Science Foundation of Shanghai (24ZR1437400)。
文摘Dry-coating electrode fabrication technologies have emerged as a promising solution for green and low-cost battery manufacturing,which can eliminate the use of contaminative and toxic solvents that challenge current battery industry.The key challenges of current dry-coating electrode fabrication lie in the uneven dispersion of various components and limited scalability.In this review,we introduce the fundamental mechanisms and recent advances in dry-coating electrode fabrication technologies,with a focus on key strategies for material design and process optimization that can promote structural integrity and electrochemical performance of the dry-coating electrodes.We also discuss the effectiveness of these innovative approaches towards promoted processing and scalability.In addition,several solutions regarding inorganic additives,composite binders,and lowmelting-point additives are further introduced,which shows promise to address the component agglomeration and interface adhesion.Moreover,we prospect the deployment of dry-coating electrode fabrication technologies in solid-state batteries and conversion-type batteries,where the solvent-free nature and interfacial compatibility offer appealing benefits.The current challenges and future opportunities for dry-coating electrode fabrication technologies are summarized,aiming to provide valuable insights to this emerging field.
基金supported by specific university research(Grant No.:A1_FCHI_2022_006).
文摘The properties of dry-coated paracetamol particles(fast-dissolving model drug)with carnauba wax particles as the coating agent(dissolution retardant)were investigated.Raman mapping technique was used to non-destructively examine the thickness and homogeneity of coated particles.The results showed that the wax existed in two forms on the surface of the paracetamol particles,forming a porous coating layer:i)whole wax particles on the surface of paracetamol and glued together with other wax surface particles,and ii)deformed wax particles spread on the surface.Regardless of the final particle size fraction(between 100 and 800 mm),the coating thickness had high variability,with average thickness of 5.9±4.2 mm.The ability of carnauba wax to decrease the dissolution rate of paracetamol was confirmed by dissolution of powder and tablet formulations.The dissolution was slower for larger coated particles.Tableting further reduced the dissolution rate,clearly indicating the impact of subsequent formulation processes on the final quality of the product.
文摘A novel statistical approach to evaluate the manufacturing quality of press coated tablets in terms of the centering of their core is presented. We also provide a formula to determine the necessary sample size. This approach is applied to real data.
