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Innovative trends in RNA interference drugs:a comprehensive patent analysis
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作者 Xing Li Lu Ma +2 位作者 Yali Zhao Xiaoxia Zhang Zijia Li 《Journal of Chinese Pharmaceutical Sciences》 2025年第8期701-714,共14页
Nucleic acid drugs represent the third wave of innovation in drug research and development,succeeding small-molecule and antibody drugs.These drugs,particularly RNA interference(RNAi)therapies,have become a pivotal fo... Nucleic acid drugs represent the third wave of innovation in drug research and development,succeeding small-molecule and antibody drugs.These drugs,particularly RNA interference(RNAi)therapies,have become a pivotal focus in the pharmaceutical industry.RNAi drugs are extensively utilized in the treatment of chronic and rare diseases due to their exceptional gene-silencing efficiency,manageable side effects,and straightforward synthesis process.This study undertook a thorough analysis of the global landscape of RNAi drug patents,highlighting the latest technological advancements and trends.We meticulously identified and cataloged the key technologies that dominated this patent landscape.The goal was to provide valuable insights and references for researchers involved in the development of RNAi drugs within the domestic pharmaceutical sector. 展开更多
关键词 Nucleic acid drugs RNA interference(RNAi)drugs siRNA Patent analysis
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