We applied double-difference tomography to relocate seismic events and determine the lithospheric velocity structure beneath the New Britain Island arc and the South Bismarck Sea Basin,based on the local P wave arriva...We applied double-difference tomography to relocate seismic events and determine the lithospheric velocity structure beneath the New Britain Island arc and the South Bismarck Sea Basin,based on the local P wave arrival time dataset collected by the International Seismological Centre.Results of the seismic relocation and velocity inversion show that the subduction of Solomon Sea Plate along the New Britain Trench is spatially different above 150 km,and the subduction angle of the slab on the west side is higher than that on the east side.The relocated earthquakes also show that there are double seismic zones at the depths of about 30–90km beneath the New Britain Island Arc.The velocity structure shows that the dehydration of the subducting slab caused the low-velocity anomalies in mantle wedge above the slab,which are associated with the magmatic activities around the New Guinea-New Britain Island arc.Moreover,it shows that there is another low-velocity anomaly zone beneath the Bismarck mid-oceanic ridge with spatial variation.Beneath the west of the Bismarck mid-oceanic ridge,the low-velocity anomaly is weakly connected to the subducted Solomon Sea slab.Conversely,the low-velocity anomaly beneath the Manus Sea Basin is highly intertwined to the subducting slab and its mantle wedge,indicating that the subduction of the Solomon Sea Plate might be a key deep dynamic factor that drives the spreading of the Manus Sea Basin and the separation of the Bismarck Plate.展开更多
West Java in the western part of the Sunda Arc has a relatively high seismicity due to subduction activity and faults.In this study,double-difference tomography was used to obtain the 3D velocity tomograms of P and S ...West Java in the western part of the Sunda Arc has a relatively high seismicity due to subduction activity and faults.In this study,double-difference tomography was used to obtain the 3D velocity tomograms of P and S waves beneath the western part of Java.To infer the geometry of the structure beneath the study area,precise earthquake hypo・center determination was first performed before tomographic imaging.For this,earthquake waveform data were extracted from the regional Meteorological,Climatological,Geophysical Agency(BMKG)network of Indonesia from South Sumatra to Central Java.The P and S arrival times for about 1,000 events in the period April 2009 to July 2016 were selected,the key features being events of magnitude>3,azimuthal gap<210°and number of phases>8.A nonlinear method using the oct-tree sampling algorithm from the NonLinLoc program was employed to determine the earthquake hypocenters.The hypocenter locations were then relocated using double-difference tomography(tomoDD).A significant reduction of travel-time(root mean square basis)and a better clustering of earthquakes were achieved which correlated well with the geological structure in West Java.Double-difference tomography was found to give a clear velocity structure,especially beneath the volcanic arc area,i.e.,under Mt Anak Krakatau,Mt Salak and the mountains complex in the southern part of West Java.Low velocity anomalies for the P and S waves as well as the vp/vs ratio below the volcanoes indicated possible partial melting of the upper mantle which ascended from the subducted slab beneath the volcanic arc.展开更多
The Haicheng earthquake （Ms 7.3） occurred in Liaoning Province （39°N-43°N, 120°E-126°E ）, China on February 4, 1975. The mortality rate was only 0.02% owing to the first timely and accurate pre...The Haicheng earthquake （Ms 7.3） occurred in Liaoning Province （39°N-43°N, 120°E-126°E ）, China on February 4, 1975. The mortality rate was only 0.02% owing to the first timely and accurate prediction, although the area affected by the earthquake was 9200 km^2 and covered cities with a population density of 1000 p/km^2. In this study, the double- difference （DD） tomography method was used to obtain high-resolution three-dimensional （3D） P- and S-wave velocity （Vp and Vs） structures and Vp/Vs as well as the earthquake locations. Tomography results suggest that velocity structure at shallow depth coincides well with topography and sediment thickness. The earthquake locations form a northwest-striking zone associated with the Jinzhou（JZ） Fault and a northeast-striking zone associated with the Haichenghe-Dayanghe （HD） Fault, and suggest that the JZ Fault consists of three faults and the Ms 7.3 Haicheng earthquake originated at the intersection of the JZ and the Faults. Low- velocity zones （LVZs） with low Vp/Vs are observed at 15-20 km depth beneath the Haicheng （HC） region. We interpret the LVZs in the middle crust as regions of fluids, suggesting rock dehydration at high temperatures. The LVZs and low Vp/Vs in the upper crust are attributed to groundwater-filled cracks and pores. We believe that large crustal earthquakes in this area are caused by the combination of faulting and fluid movement in the middle crust.展开更多
Overt and harmful diabetes mellitus(DM)has detrimental effects on individuals and,by extension,the community.Among the microvascular DM complications is diabetic retinopathy(DR).DR may cause irreversible vision deteri...Overt and harmful diabetes mellitus(DM)has detrimental effects on individuals and,by extension,the community.Among the microvascular DM complications is diabetic retinopathy(DR).DR may cause irreversible vision deterioration in cases of poor blood glucose regulation.Changes in vascular permeability are key trigger points for diabetic macular edema(DME),a condition characterized by the accumulation of fluid in the macula.The development of vascular endothelial growth factor(VEGF)pathway inhibitors has provided a pathogenesis-based treatment approach for DME.Optical coherence tomography(OCT)provides highresolution imaging of the anatomy,including the aging of DME and its structural damage,in distinct morphologic subtypes of macular edema,thereby supporting the assessment of macular edema treatment.The availability of repeated OCT monitoring provides clinical reassurance through the treatment.OCT angiography(OCTA)provides retinal blood flow maps with high spatial resolution.The ability promotes an understanding of disease pathogenesis and facilitates the implementation of new therapeutic methods.This review compares the potential of OCT and OCTA in the diagnosis and treatment of DME,as well as their respective therapeutic applications.展开更多
BACKGROUND Early screening,preoperative staging,and diagnosis of lymph node metastasis are crucial for improving the prognosis of gastric cancer(GC).AIM To evaluate the diagnostic value of combined multidetector compu...BACKGROUND Early screening,preoperative staging,and diagnosis of lymph node metastasis are crucial for improving the prognosis of gastric cancer(GC).AIM To evaluate the diagnostic value of combined multidetector computed tomography(MDCT)and gastrointestinal endoscopy for GC screening,preoperative staging,and lymph node metastasis detection,thereby providing a reference for clinical diagnosis and treatment.METHODS In this retrospective study clinical and imaging data of 134 patients with suspected GC who were admitted between January 2023 and October 2024 were initially reviewed.According to the inclusion and exclusion criteria,102 patients were finally enrolled in the analysis.All enrolled patients had undergone both MDCT and gastrointestinal endoscopy examinations prior to surgical intervention.Preoperative clinical staging and lymph node metastasis findings were compared with pathological results.RESULTS The combined use of MDCT and gastrointestinal endoscopy demonstrated a sensitivity of 98.53%,specificity of 97.06%,accuracy of 98.04%,positive predictive value of 98.53%,and negative predictive value of 97.06%for diagnosing GC.These factors were all significantly higher than those of MDCT or endoscopy alone(P<0.05).The accuracy rates of the combined approach for detecting clinical T and N stages were 97.06%and 92.65%,respectively,outperforming MDCT alone(86.76% and 79.41%)and endoscopy alone(85.29% and 70.59%)(P<0.05).Among 68 patients with confirmed GC,50(73.53%)were pathologically diagnosed with lymph node metastasis.The accuracy for detecting lymph node metastasis was 66.00%with endoscopy,76.00%with MDCT,and 92.00% with the combined approach,all with statistically significant differences(P<0.05).CONCLUSION The combined application of MDCT and gastrointestinal endoscopy enhanced diagnostic accuracy for GC,provided greater consistency in preoperative staging,and improved the detection of lymph node metastasis,thereby demonstrating significant clinical utility.展开更多
Although previous studies have demonstrated that transcranial focused ultrasound stimulation protects the ischemic brain,clear criteria for the stimulation time window and intensity are lacking.Electrical impedance to...Although previous studies have demonstrated that transcranial focused ultrasound stimulation protects the ischemic brain,clear criteria for the stimulation time window and intensity are lacking.Electrical impedance tomography enables real-time monitoring of changes in cerebral blood perfusion within the ischemic brain,but investigating the feasibility of using this method to assess post-stroke rehabilitation in vivo remains critical.In this study,ischemic stroke was induced in rats through middle cerebral artery occlusion surgery.Transcranial focused ultrasound stimulation was used to treat the rat model of ischemia,and electrical impedance tomography was used to measure impedance during both the acute stage of ischemia and the rehabilitation stage following the stimulation.Electrical impedance tomography results indicated that cerebral impedance increased after the onset of ischemia and decreased following transcranial focused ultrasound stimulation.Furthermore,the stimulation promoted motor function recovery,reduced cerebral infarction volume in the rat model of ischemic stroke,and induced the expression of brain-derived neurotrophic factor in the ischemic brain.Our results also revealed a significant correlation between the impedance of the ischemic brain post-intervention and improvements in behavioral scores and infarct volume.This study shows that daily administration of transcranial focused ultrasound stimulation for 20 minutes to the ischemic hemisphere 24 hours after cerebral ischemia enhanced motor recovery in a rat model of ischemia.Additionally,our findings indicate that electrical impedance tomography can serve as a valuable tool for quantitatively evaluating rehabilitation after ischemic stroke in vivo.These findings suggest the feasibility of using impedance data collected via electrical impedance tomography to clinically assess the effects of rehabilitatory interventions for patients with ischemic stroke.展开更多
A P-wave velocity model was built in the central southern of the Tanlu Fault based on double-difference tomography.The results suggest the presence of a low-velocity anomaly extending from the surface to a depth of 25...A P-wave velocity model was built in the central southern of the Tanlu Fault based on double-difference tomography.The results suggest the presence of a low-velocity anomaly extending from the surface to a depth of 25 km around the Tanlu and Feixi Faults,representing fault-related fluids caused by partial melting.The relocated earthquakes indicate a significant concentration of seismic activity above 20 km around the Tanlu and Feixi Faults,suggesting that prominent fault systems possibly serve as conduits for the upward migration of deep minerals.The proposed geodynamic model,supported by geological and geophysical data,suggests that the migration of deep mineralized materials extends along the Tanlu Fault.The obtained results serve as a crucial foundation for elucidating the intricate process of mineralization in the central southern segment of the Tanlu Fault,thereby enhancing comprehension regarding the interaction among ore body formation,fault fluids,localized melting,and seismic activity.展开更多
The Longmenshan(LMS)fault zone is located at the junction of the eastern Tibetan Plateau and the Sichuan Basin and is of great significance for studying regional tectonics and earthquake hazards.Although regional velo...The Longmenshan(LMS)fault zone is located at the junction of the eastern Tibetan Plateau and the Sichuan Basin and is of great significance for studying regional tectonics and earthquake hazards.Although regional velocity models are available for the LMS fault zone,high-resolution velocity models are lacking.Therefore,a dense array of 240 short-period seismometers was deployed around the central segment of the LMS fault zone for approximately 30 days to monitor earthquakes and characterize fine structures of the fault zone.Considering the large quantity of observed seismic data,the data processing workflow consisted of deep learning-based automatic earthquake detection,phase arrival picking,and association.Compared with the earthquake catalog released by the China Earthquake Administration,many more earthquakes were detected by the dense array.Double-difference seismic tomography was adopted to determine V_(p),V_(s),and V_(p)/V_(s)models as well as earthquake locations.The checkerboard test showed that the velocity models have spatial resolutions of approximately 5 km in the horizontal directions and 2 km at depth.To the west of the Yingxiu–Beichuan Fault(YBF),the Precambrian Pengguan complex,where most of earthquakes occurred,is characterized by high velocity and low V_(p)/V_(s)values.In comparison,to the east of the YBF,the Upper Paleozoic to Jurassic sediments,where few earthquakes occurred,show low velocity and high V_(p)/V_(s)values.Our results suggest that the earthquake activity in the LMS fault zone is controlled by the strength of the rock compositions.When the high-resolution velocity models were combined with the relocated earthquakes,we were also able to delineate the fault geometry for different faults in the LMS fault zone.展开更多
In this paper,we use the double difference location method based on waveform crosscorrelation algorithm for precise positioning of the Three Gorges Reservoir( TGR)earthquakes and analysis of seismic activity. First,we...In this paper,we use the double difference location method based on waveform crosscorrelation algorithm for precise positioning of the Three Gorges Reservoir( TGR)earthquakes and analysis of seismic activity. First,we use the bi-spectrum cross-correlation method to analyze the seismic waveform data of TGR encrypted networks from March,2009 to December,2010,and evaluate the quality of waveform cross-correlation analysis.Combined with the waveform cross-correlation of data obtained, we use the double difference method to relocate the earthquake position. The results show that location precision using bi-spectrum verified waveform cross-correlation data is higher than that by using other types of data,and the mean 2 sig-error in EW,NS and UD are 3.2 m,3.9 m and 6.2 m,respectively. For the relocation of the Three Gorges Reservoir earthquakes,the results show that the micro-earthquakes along the Shenlongxi river in the Badong reservoir area obviously show the characteristics of three linear zones with nearly east-west direction,which is in accordance with the small faults and carbonate strata line of the neotectonic period,revealing the reservoir water main along the underground rivers or caves permeated and induced seismic activity. The stronger earthquakes may have resulted from small earthquakes through the active layers.展开更多
We report on tests of combined positron emission tomography(PET)andfluorescence molecular tomography(FMT)imaging system for in vivo investigation on small animals.A nude mouse was inoculated with MD-MB-231 breast canc...We report on tests of combined positron emission tomography(PET)andfluorescence molecular tomography(FMT)imaging system for in vivo investigation on small animals.A nude mouse was inoculated with MD-MB-231 breast cancer cells which expressed redfluorescent protein(RFP).For FMT system,reflective illumination mode was adopted with full-angle data acquisition.[18F]-Fluorodeoxyglucose([18F]-FDG)was used as radioactive tracer for PET.Both data were acquired simultaneously and then reconstructed separately before fusion.Fluorescent tomography results showed exactly where the tumor was located while PET results offered more metabolic information.Results confirmed feasibility for tumor detection and showed superiority to single modality imaging.展开更多
Photon-counting computed tomography(PCCT)represents a significant advancement in pediatric cardiovascular imaging.Traditional CT systems employ energy-integrating detectors that convert X-ray photons into visible ligh...Photon-counting computed tomography(PCCT)represents a significant advancement in pediatric cardiovascular imaging.Traditional CT systems employ energy-integrating detectors that convert X-ray photons into visible light,whereas PCCT utilizes photon-counting detectors that directly transform X-ray photons into electric signals.This direct conversion allows photon-counting detectors to sort photons into discrete energy levels,thereby enhancing image quality through superior noise reduction,improved spatial and contrast resolution,and reduced artifacts.In pediatric applications,PCCT offers substantial benefits,including lower radiation doses,which may help reduce the risk of malignancy in pediatric patients,with perhaps greater potential to benefit those with repeated exposure from a young age.Enhanced spatial resolution facilitates better visualization of small structures,vital for diagnosing congenital heart defects.Additionally,PCCT’s spectral capabilities improve tissue characterization and enable the creation of virtual monoenergetic images,which enhance soft-tissue contrast and potentially reduce contrast media doses.Initial clinical results indicate that PCCT provides superior image quality and diagnostic accuracy compared to conven-tional CT,particularly in challenging pediatric cardiovascular cases.As PCCT technology matures,further research and standardized protocols will be essential to fully integrate it into pediatric imaging practices,ensuring optimized diagnostic outcomes and patient safety.展开更多
The locations of about 400 earthquakes in Yangjiang, Guangdong Province are determined using the double, difference earthquake location algorithm （DDA）. The seismicity pattern becomes concentrated from discrete grid...The locations of about 400 earthquakes in Yangjiang, Guangdong Province are determined using the double, difference earthquake location algorithm （DDA）. The seismicity pattern becomes concentrated from discrete grids. The rupture characteristics of the Yangjiang earthquake sequence show a conjugated distribution in NW and NE directions. The major distribution trends NE and dips NE with an angle of 30^o and a length of 30km,and the minor distribution trends NW and dips SE with an angle of 30^o and a length of 20km. The focal depth is 5km - 15km. The distribution of the Enping earthquake sequence,which is not far from Yangjiang,is NW-trending. The relationship between hypocenter distribution and geological structure is discussed.展开更多
Biliary tract cancer(BTC)is a group of heterogeneous sporadic diseases,including intrahepatic,hilar,and distal cholangiocarcinoma,as well as gallbladder cancer.BTC is characterized by high invasiveness and extremely p...Biliary tract cancer(BTC)is a group of heterogeneous sporadic diseases,including intrahepatic,hilar,and distal cholangiocarcinoma,as well as gallbladder cancer.BTC is characterized by high invasiveness and extremely poor prognosis,with a global increased incidence due to intrahepatic cholangiocarcinoma(ICC).The 18Ffludeoxyglucose positron emission tomography(PET)computed tomography(18F-FDG PET/CT)combines glucose metabolic information(reflecting the glycolytic activity of tumor cells)with anatomical structure to assess tumor metabolic heterogeneity,systemic metastasis,and molecular characteristics noninvasively,overcoming the limitations of traditional imaging in the detection of micrometastases and recurrent lesions.18F-FDG PET/CT offers critical insights in clinical staging,therapeutic evaluation,and prognostic prediction of BTC.This article reviews research progress in this field over the past decade,with a particular focus on the advances made in the last 3 years,which have not been adequately summarized and recognized.The research paradigm in this field is shifting from qualitative to quantitative studies,and there have been significant breakthroughs in using 18F-FDG PET/CT metabolic information to predict gene expression in ICC.Radiomics and deep learning techniques have been applied to ICC for prognostic prediction and differential diagnosis.Additionally,PET/magnetic resonance imaging is increasingly demonstrating its value in this field.展开更多
AIM:To investigate the value of optical coherence tomography angiography(OCTA)indicators in the diagnosis of diabetic retinopathy(DR),and to provide patients with diabetic nephropathy(DN)with more sensitive OCTA scree...AIM:To investigate the value of optical coherence tomography angiography(OCTA)indicators in the diagnosis of diabetic retinopathy(DR),and to provide patients with diabetic nephropathy(DN)with more sensitive OCTA screening indicators to detect concurrent DR at an early stage.METHODS:A total of 200 patients who treated in the ophthalmology department of the Seventh Affiliated Hospital,Sun Yat-sen University from 2022 to 2023 were included,including 95 first-diagnosed DR patients and 105 patients without DR,and all patients underwent OCTA examination and a collection of demographics and renal function parameters.After a quality check,automated measurements of the foveal avascular zone area,vessel density(VD),and perfusion density(PD)of both 3 mm×3 mm and 6 mm×6 mm windows were obtained.RESULTS:Using random forest and multivariate Logistic regression methods,we developed a diagnostic model for DR based on 12 variables(age,FBG,SBP,DBP,HbA1c,ALT,ALP,urea/Scr,DM duration,HUA,DN,and CMT).Adding specific OCTA parameters enhanced the efficacy of the existing diagnostic model for DR(outer vessel density in 6 mm×6 mm window,AUC=0.837 vs 0.819,P=0.03).In the study of DN patients,the parameters in the 6 mm×6 mm window improved the diagnostic efficacy of DR(inner VD;outer VD;full VD;outer PD;full PD).CONCLUSION:The outer VD in the 6 mm×6 mm window can enhance the efficacy of the traditional DR diagnostic model.Meanwhile,compared with the 3 mm×3 mm window,the microvascular parameters in the 6 mm×6 mm window focusing on DN patients can be more sensitive to diagnosing the occurrence of DR.展开更多
Nowadays,presynaptic dopaminergic positron emission tomography,which assesses deficiencies in dopamine synthesis,storage,and transport,is widely utilized for early diagnosis and differential diagnosis of parkinsonism....Nowadays,presynaptic dopaminergic positron emission tomography,which assesses deficiencies in dopamine synthesis,storage,and transport,is widely utilized for early diagnosis and differential diagnosis of parkinsonism.This review provides a comprehensive summary of the latest developments in the application of presynaptic dopaminergic positron emission tomography imaging in disorders that manifest parkinsonism.We conducted a thorough literature search using reputable databases such as PubMed and Web of Science.Selection criteria involved identifying peer-reviewed articles published within the last 5 years,with emphasis on their relevance to clinical applications.The findings from these studies highlight that presynaptic dopaminergic positron emission tomography has demonstrated potential not only in diagnosing and differentiating various Parkinsonian conditions but also in assessing disease severity and predicting prognosis.Moreover,when employed in conjunction with other imaging modalities and advanced analytical methods,presynaptic dopaminergic positron emission tomography has been validated as a reliable in vivo biomarker.This validation extends to screening and exploring potential neuropathological mechanisms associated with dopaminergic depletion.In summary,the insights gained from interpreting these studies are crucial for enhancing the effectiveness of preclinical investigations and clinical trials,ultimately advancing toward the goals of neuroregeneration in parkinsonian disorders.展开更多
BACKGROUND Atypical optic neuritis,consisting of neuromyelitis optica spectrum disorders(NMOSD)or myelin oligodendrocyte glycoprotein antibody disease(MOGAD),has a very similar presentation but different prognostic im...BACKGROUND Atypical optic neuritis,consisting of neuromyelitis optica spectrum disorders(NMOSD)or myelin oligodendrocyte glycoprotein antibody disease(MOGAD),has a very similar presentation but different prognostic implications and longterm management strategies.Vascular and metabolic factors are being thought to play a role in such autoimmune neuro-inflammatory disorders,apart from the obvious immune mediated damage.With the advent of optical coherence tomography angiography(OCTA),it is easy to pick up on these subclinical macular microvascular and structural changes.AIM To study the macular microvascular and structural changes on OCTA in atypical optic neuritis.METHODS This observational cross-sectional study involved 8 NMOSD and 17 MOGAD patients,diagnosed serologically,as well as 10 healthy controls.Macular vascular density(MVD)and ganglion cell+inner plexiform layer thickness(GCIPL)were studied using OCTA.RESULTS There was a significant reduction in MVD in NMOSD and MOGAD affected as well as unaffected eyes when compared with healthy controls.NMOSD and MOGAD affected eyes had significant GCIPL thinning compared with healthy controls.NMOSD unaffected eyes did not show significant GCIPL thinning compared to healthy controls in contrast to MOGAD unaffected eyes.On comparing NMOSD with MOGAD,there was no significant difference in terms of MVD or GCIPL in the affected or unaffected eyes.CONCLUSION Although significant microvascular and structural changes are present on OCTA between atypical optic neuritis and normal patients,they could not help in differentiating between NMOSD and MOGAD cases.展开更多
Dense-array ambient noise tomography is a powerful tool for achieving high-resolution subsurface imag-ing,significantly impacting geohazard prevention and control.Conventional dense-array studies,how-ever,require simu...Dense-array ambient noise tomography is a powerful tool for achieving high-resolution subsurface imag-ing,significantly impacting geohazard prevention and control.Conventional dense-array studies,how-ever,require simultaneous observations of numerous stations for extensive coverage.To conduct a comprehensive karst feature investigation with limited stations,we designed a new synchronous-asyn-chronous observation system that facilitates dense array observations.We conducted two rounds of asynchronous observations,each lasting approximately 24 h,in combination with synchronous backbone stations.We achieved wide-ranging coverage of the study area utilizing 197 nodal receivers,with an average station spacing of 7 m.The beamforming results revealed distinct variations in the noise source distributions between day and night.We estimated the source strength in the stationary phase zone and used a weighting scheme for stacking the cross-correlation functions(C ^(1) functions)to suppress the influ-ence of nonuniform noise source distributions.The weights were derived from the similarity coefficients between multicomponent C^(1)functions related to Rayleigh waves.We employed the cross-correlation of C ^(1) functions(C^(2)methods)to obtain the empirical Green’s functions between asynchronous stations.To eliminate artifacts in C ^(2) functions from higher-mode surface waves in C^(1)functions,we filtered the C^(1)functions on the basis of different particle motions linked to multimode Rayleigh waves.The dispersion measurements of Rayleigh waves obtained from both the C^(1)and C^(2)functions were utilized in surface wave tomography.The inverted three-dimensional(3D)shear-wave(S-wave)velocity model reveals two significant low-velocity zones at depths ranging from 40 to 60 m,which align well with the karst caves found in the drilling data.The method of short-term synchronous-asynchronous ambient noise tomography shows promise as a cost-effective and efficient approach for urban geohazard investigations.展开更多
Pericoronary adipose tissue(PCAT)plays an important role in the pathogenesis and progression of cardiovascular diseases due to its bidirectional communication with the coronary artery wall.In recent years,PCAT paramet...Pericoronary adipose tissue(PCAT)plays an important role in the pathogenesis and progression of cardiovascular diseases due to its bidirectional communication with the coronary artery wall.In recent years,PCAT parameters measured using coronary computed tomography have emerged as potential noninvasive imaging biomarkers for quantifying coronary artery inflammation,with significant clinical value in the early detection,disease progression assessment,treatment efficacy evaluation,and prognosis prediction of cardiovascular diseases.Furthermore,new technologies such as PCAT radiomics analysis have broadened its potential applications in evaluating coronary plaque vulnerability,predicting cardiovascular events,and improving risk stratification.This review discusses recent advances in PCAT research,focusing on its role in coronary artery disease risk identification and inflammation monitoring,and aims to offer imaging-based insights to support its future clinical use in cardiovascular disease management.展开更多
Angiomyolipomas(AMLs)represent the most common benign solid renal tumors.The frequency of their detection in the general population is increasing owing to advances in imaging technology.The objective of this review is...Angiomyolipomas(AMLs)represent the most common benign solid renal tumors.The frequency of their detection in the general population is increasing owing to advances in imaging technology.The objective of this review is to discuss computed tomography(CT)and magnetic resonance imaging findings for both typical and atypical renal AMLs,along with their associated complications.AMLs are typically defined as solid triphasic tumors composed of varying amounts of dysmorphic and tortuous blood vessels,smooth muscle components and adipose tissue.In an adult,a classical renal AML appears as a solid,heterogeneous renal cortical mass with macroscopic fat.However,up to 5%of AMLs contain minimal fat and cannot be reliably diagnosed by imaging.Fat-poor AMLs can appear as hyperattenuating masses on unenhanced CT and as hypointense masses on T2WI;other AMLs may be isodense or exhibit cystic components.Hemorrhage is the most common complication,and AMLs with hemorrhage can mimic other tumors,making their diagnosis challenging.Understanding the variable and heterogeneous nature of this neoplasm to correctly classify renal AMLs and to avoid misdiagnosis of other renal lesions is crucial.展开更多
The paper presents experimental investigation results of crack pattern change in cement pastes caused by external sulfate attack(ESA).To visualize the formation and development of cracks in cement pastes under ESA,an ...The paper presents experimental investigation results of crack pattern change in cement pastes caused by external sulfate attack(ESA).To visualize the formation and development of cracks in cement pastes under ESA,an X-ray computed tomography(X-ray CT)was used,i e,the tomography system of Zeiss Xradia 510 versa.The results indicate that X-CT can monitor the development process and distribution characteristics of the internal cracks of cement pastes under ESA with attack time.In addition,the C3A content in the cement significantly affects the damage mode of cement paste specimens during sulfate erosion.The damage of ordinary Portland cement(OPC)pastes subjected to sulfate attack with high C3A content are severe,while the damage of sulfate resistant Portland cement(SRPC)pastes is much smaller than that of OPC pastes.Furthermore,a quadratic function describes the correlation between the crack volume fraction and development depth for two cement pastes immermed in sulfate solution.展开更多
基金supported by the National Natural Science Foundation of China(Nos.41906048 and 91858215).
文摘We applied double-difference tomography to relocate seismic events and determine the lithospheric velocity structure beneath the New Britain Island arc and the South Bismarck Sea Basin,based on the local P wave arrival time dataset collected by the International Seismological Centre.Results of the seismic relocation and velocity inversion show that the subduction of Solomon Sea Plate along the New Britain Trench is spatially different above 150 km,and the subduction angle of the slab on the west side is higher than that on the east side.The relocated earthquakes also show that there are double seismic zones at the depths of about 30–90km beneath the New Britain Island Arc.The velocity structure shows that the dehydration of the subducting slab caused the low-velocity anomalies in mantle wedge above the slab,which are associated with the magmatic activities around the New Guinea-New Britain Island arc.Moreover,it shows that there is another low-velocity anomaly zone beneath the Bismarck mid-oceanic ridge with spatial variation.Beneath the west of the Bismarck mid-oceanic ridge,the low-velocity anomaly is weakly connected to the subducted Solomon Sea slab.Conversely,the low-velocity anomaly beneath the Manus Sea Basin is highly intertwined to the subducting slab and its mantle wedge,indicating that the subduction of the Solomon Sea Plate might be a key deep dynamic factor that drives the spreading of the Manus Sea Basin and the separation of the Bismarck Plate.
基金the Directorate General of Resources for Science Technologythe Higher Education of the Republic of Indonesia for granting a PMDSU scholarship to SR
文摘West Java in the western part of the Sunda Arc has a relatively high seismicity due to subduction activity and faults.In this study,double-difference tomography was used to obtain the 3D velocity tomograms of P and S waves beneath the western part of Java.To infer the geometry of the structure beneath the study area,precise earthquake hypo・center determination was first performed before tomographic imaging.For this,earthquake waveform data were extracted from the regional Meteorological,Climatological,Geophysical Agency(BMKG)network of Indonesia from South Sumatra to Central Java.The P and S arrival times for about 1,000 events in the period April 2009 to July 2016 were selected,the key features being events of magnitude>3,azimuthal gap<210°and number of phases>8.A nonlinear method using the oct-tree sampling algorithm from the NonLinLoc program was employed to determine the earthquake hypocenters.The hypocenter locations were then relocated using double-difference tomography(tomoDD).A significant reduction of travel-time(root mean square basis)and a better clustering of earthquakes were achieved which correlated well with the geological structure in West Java.Double-difference tomography was found to give a clear velocity structure,especially beneath the volcanic arc area,i.e.,under Mt Anak Krakatau,Mt Salak and the mountains complex in the southern part of West Java.Low velocity anomalies for the P and S waves as well as the vp/vs ratio below the volcanoes indicated possible partial melting of the upper mantle which ascended from the subducted slab beneath the volcanic arc.
基金supported by the National Natural Science Foundation of China(Grants Nos.41430322 and 41474030)the National Key Research and Development Project of China(Grants No.2016YFC0600301)
文摘The Haicheng earthquake （Ms 7.3） occurred in Liaoning Province （39°N-43°N, 120°E-126°E ）, China on February 4, 1975. The mortality rate was only 0.02% owing to the first timely and accurate prediction, although the area affected by the earthquake was 9200 km^2 and covered cities with a population density of 1000 p/km^2. In this study, the double- difference （DD） tomography method was used to obtain high-resolution three-dimensional （3D） P- and S-wave velocity （Vp and Vs） structures and Vp/Vs as well as the earthquake locations. Tomography results suggest that velocity structure at shallow depth coincides well with topography and sediment thickness. The earthquake locations form a northwest-striking zone associated with the Jinzhou（JZ） Fault and a northeast-striking zone associated with the Haichenghe-Dayanghe （HD） Fault, and suggest that the JZ Fault consists of three faults and the Ms 7.3 Haicheng earthquake originated at the intersection of the JZ and the Faults. Low- velocity zones （LVZs） with low Vp/Vs are observed at 15-20 km depth beneath the Haicheng （HC） region. We interpret the LVZs in the middle crust as regions of fluids, suggesting rock dehydration at high temperatures. The LVZs and low Vp/Vs in the upper crust are attributed to groundwater-filled cracks and pores. We believe that large crustal earthquakes in this area are caused by the combination of faulting and fluid movement in the middle crust.
文摘Overt and harmful diabetes mellitus(DM)has detrimental effects on individuals and,by extension,the community.Among the microvascular DM complications is diabetic retinopathy(DR).DR may cause irreversible vision deterioration in cases of poor blood glucose regulation.Changes in vascular permeability are key trigger points for diabetic macular edema(DME),a condition characterized by the accumulation of fluid in the macula.The development of vascular endothelial growth factor(VEGF)pathway inhibitors has provided a pathogenesis-based treatment approach for DME.Optical coherence tomography(OCT)provides highresolution imaging of the anatomy,including the aging of DME and its structural damage,in distinct morphologic subtypes of macular edema,thereby supporting the assessment of macular edema treatment.The availability of repeated OCT monitoring provides clinical reassurance through the treatment.OCT angiography(OCTA)provides retinal blood flow maps with high spatial resolution.The ability promotes an understanding of disease pathogenesis and facilitates the implementation of new therapeutic methods.This review compares the potential of OCT and OCTA in the diagnosis and treatment of DME,as well as their respective therapeutic applications.
文摘BACKGROUND Early screening,preoperative staging,and diagnosis of lymph node metastasis are crucial for improving the prognosis of gastric cancer(GC).AIM To evaluate the diagnostic value of combined multidetector computed tomography(MDCT)and gastrointestinal endoscopy for GC screening,preoperative staging,and lymph node metastasis detection,thereby providing a reference for clinical diagnosis and treatment.METHODS In this retrospective study clinical and imaging data of 134 patients with suspected GC who were admitted between January 2023 and October 2024 were initially reviewed.According to the inclusion and exclusion criteria,102 patients were finally enrolled in the analysis.All enrolled patients had undergone both MDCT and gastrointestinal endoscopy examinations prior to surgical intervention.Preoperative clinical staging and lymph node metastasis findings were compared with pathological results.RESULTS The combined use of MDCT and gastrointestinal endoscopy demonstrated a sensitivity of 98.53%,specificity of 97.06%,accuracy of 98.04%,positive predictive value of 98.53%,and negative predictive value of 97.06%for diagnosing GC.These factors were all significantly higher than those of MDCT or endoscopy alone(P<0.05).The accuracy rates of the combined approach for detecting clinical T and N stages were 97.06%and 92.65%,respectively,outperforming MDCT alone(86.76% and 79.41%)and endoscopy alone(85.29% and 70.59%)(P<0.05).Among 68 patients with confirmed GC,50(73.53%)were pathologically diagnosed with lymph node metastasis.The accuracy for detecting lymph node metastasis was 66.00%with endoscopy,76.00%with MDCT,and 92.00% with the combined approach,all with statistically significant differences(P<0.05).CONCLUSION The combined application of MDCT and gastrointestinal endoscopy enhanced diagnostic accuracy for GC,provided greater consistency in preoperative staging,and improved the detection of lymph node metastasis,thereby demonstrating significant clinical utility.
基金supported by the Fundamental Research Funds for the Central Universities,Nos.G2021KY05107,G2021KY05101the National Natural Science Foundation of China,Nos.32071316,32211530049+1 种基金the Natural Science Foundation of Shaanxi Province,No.2022-JM482the Education and Teaching Reform Funds for the Central Universities,No.23GZ230102(all to LL and HH).
文摘Although previous studies have demonstrated that transcranial focused ultrasound stimulation protects the ischemic brain,clear criteria for the stimulation time window and intensity are lacking.Electrical impedance tomography enables real-time monitoring of changes in cerebral blood perfusion within the ischemic brain,but investigating the feasibility of using this method to assess post-stroke rehabilitation in vivo remains critical.In this study,ischemic stroke was induced in rats through middle cerebral artery occlusion surgery.Transcranial focused ultrasound stimulation was used to treat the rat model of ischemia,and electrical impedance tomography was used to measure impedance during both the acute stage of ischemia and the rehabilitation stage following the stimulation.Electrical impedance tomography results indicated that cerebral impedance increased after the onset of ischemia and decreased following transcranial focused ultrasound stimulation.Furthermore,the stimulation promoted motor function recovery,reduced cerebral infarction volume in the rat model of ischemic stroke,and induced the expression of brain-derived neurotrophic factor in the ischemic brain.Our results also revealed a significant correlation between the impedance of the ischemic brain post-intervention and improvements in behavioral scores and infarct volume.This study shows that daily administration of transcranial focused ultrasound stimulation for 20 minutes to the ischemic hemisphere 24 hours after cerebral ischemia enhanced motor recovery in a rat model of ischemia.Additionally,our findings indicate that electrical impedance tomography can serve as a valuable tool for quantitatively evaluating rehabilitation after ischemic stroke in vivo.These findings suggest the feasibility of using impedance data collected via electrical impedance tomography to clinically assess the effects of rehabilitatory interventions for patients with ischemic stroke.
基金supported by the National Natural Science Foundation of China(Nos.42574119,42274083,41974049)partly supported by the Urban Geological Survey Project of Linyi,Shandong Province,China(No.SDGP371300202102000468).
文摘A P-wave velocity model was built in the central southern of the Tanlu Fault based on double-difference tomography.The results suggest the presence of a low-velocity anomaly extending from the surface to a depth of 25 km around the Tanlu and Feixi Faults,representing fault-related fluids caused by partial melting.The relocated earthquakes indicate a significant concentration of seismic activity above 20 km around the Tanlu and Feixi Faults,suggesting that prominent fault systems possibly serve as conduits for the upward migration of deep minerals.The proposed geodynamic model,supported by geological and geophysical data,suggests that the migration of deep mineralized materials extends along the Tanlu Fault.The obtained results serve as a crucial foundation for elucidating the intricate process of mineralization in the central southern segment of the Tanlu Fault,thereby enhancing comprehension regarding the interaction among ore body formation,fault fluids,localized melting,and seismic activity.
基金supported by the Scientific Research Foundation for High-level Talents of Anhui University of Science and Technology under Grant 2024yjrc64the National Key R&D Program of China under Grant 2018YFC1504102。
文摘The Longmenshan(LMS)fault zone is located at the junction of the eastern Tibetan Plateau and the Sichuan Basin and is of great significance for studying regional tectonics and earthquake hazards.Although regional velocity models are available for the LMS fault zone,high-resolution velocity models are lacking.Therefore,a dense array of 240 short-period seismometers was deployed around the central segment of the LMS fault zone for approximately 30 days to monitor earthquakes and characterize fine structures of the fault zone.Considering the large quantity of observed seismic data,the data processing workflow consisted of deep learning-based automatic earthquake detection,phase arrival picking,and association.Compared with the earthquake catalog released by the China Earthquake Administration,many more earthquakes were detected by the dense array.Double-difference seismic tomography was adopted to determine V_(p),V_(s),and V_(p)/V_(s)models as well as earthquake locations.The checkerboard test showed that the velocity models have spatial resolutions of approximately 5 km in the horizontal directions and 2 km at depth.To the west of the Yingxiu–Beichuan Fault(YBF),the Precambrian Pengguan complex,where most of earthquakes occurred,is characterized by high velocity and low V_(p)/V_(s)values.In comparison,to the east of the YBF,the Upper Paleozoic to Jurassic sediments,where few earthquakes occurred,show low velocity and high V_(p)/V_(s)values.Our results suggest that the earthquake activity in the LMS fault zone is controlled by the strength of the rock compositions.When the high-resolution velocity models were combined with the relocated earthquakes,we were also able to delineate the fault geometry for different faults in the LMS fault zone.
基金funded by the National Science and Technology Pillar Program(2008BAC38B04)the Special Research Fund for Seismology(16A44ZX282)
文摘In this paper,we use the double difference location method based on waveform crosscorrelation algorithm for precise positioning of the Three Gorges Reservoir( TGR)earthquakes and analysis of seismic activity. First,we use the bi-spectrum cross-correlation method to analyze the seismic waveform data of TGR encrypted networks from March,2009 to December,2010,and evaluate the quality of waveform cross-correlation analysis.Combined with the waveform cross-correlation of data obtained, we use the double difference method to relocate the earthquake position. The results show that location precision using bi-spectrum verified waveform cross-correlation data is higher than that by using other types of data,and the mean 2 sig-error in EW,NS and UD are 3.2 m,3.9 m and 6.2 m,respectively. For the relocation of the Three Gorges Reservoir earthquakes,the results show that the micro-earthquakes along the Shenlongxi river in the Badong reservoir area obviously show the characteristics of three linear zones with nearly east-west direction,which is in accordance with the small faults and carbonate strata line of the neotectonic period,revealing the reservoir water main along the underground rivers or caves permeated and induced seismic activity. The stronger earthquakes may have resulted from small earthquakes through the active layers.
基金The authors would like to thank X.Zhang,faculty of XinAoMDT Technology Co.,Ltd.,for the work of system software development.This work is supported by the National Natural Science Foundation of China under Grant Nos.81071191,60831003,30930092,30872633the Tsinghua-Yue-Yuen Medical Science Foundationthe National Basic Research Program of China(973)under Grant No.2011CB707701.
文摘We report on tests of combined positron emission tomography(PET)andfluorescence molecular tomography(FMT)imaging system for in vivo investigation on small animals.A nude mouse was inoculated with MD-MB-231 breast cancer cells which expressed redfluorescent protein(RFP).For FMT system,reflective illumination mode was adopted with full-angle data acquisition.[18F]-Fluorodeoxyglucose([18F]-FDG)was used as radioactive tracer for PET.Both data were acquired simultaneously and then reconstructed separately before fusion.Fluorescent tomography results showed exactly where the tumor was located while PET results offered more metabolic information.Results confirmed feasibility for tumor detection and showed superiority to single modality imaging.
文摘Photon-counting computed tomography(PCCT)represents a significant advancement in pediatric cardiovascular imaging.Traditional CT systems employ energy-integrating detectors that convert X-ray photons into visible light,whereas PCCT utilizes photon-counting detectors that directly transform X-ray photons into electric signals.This direct conversion allows photon-counting detectors to sort photons into discrete energy levels,thereby enhancing image quality through superior noise reduction,improved spatial and contrast resolution,and reduced artifacts.In pediatric applications,PCCT offers substantial benefits,including lower radiation doses,which may help reduce the risk of malignancy in pediatric patients,with perhaps greater potential to benefit those with repeated exposure from a young age.Enhanced spatial resolution facilitates better visualization of small structures,vital for diagnosing congenital heart defects.Additionally,PCCT’s spectral capabilities improve tissue characterization and enable the creation of virtual monoenergetic images,which enhance soft-tissue contrast and potentially reduce contrast media doses.Initial clinical results indicate that PCCT provides superior image quality and diagnostic accuracy compared to conven-tional CT,particularly in challenging pediatric cardiovascular cases.As PCCT technology matures,further research and standardized protocols will be essential to fully integrate it into pediatric imaging practices,ensuring optimized diagnostic outcomes and patient safety.
基金The research was sponsored by the Key Science and Technology R&D Program of Guangdong Province(Grant No. 2005B32601003)
文摘The locations of about 400 earthquakes in Yangjiang, Guangdong Province are determined using the double, difference earthquake location algorithm （DDA）. The seismicity pattern becomes concentrated from discrete grids. The rupture characteristics of the Yangjiang earthquake sequence show a conjugated distribution in NW and NE directions. The major distribution trends NE and dips NE with an angle of 30^o and a length of 30km,and the minor distribution trends NW and dips SE with an angle of 30^o and a length of 20km. The focal depth is 5km - 15km. The distribution of the Enping earthquake sequence,which is not far from Yangjiang,is NW-trending. The relationship between hypocenter distribution and geological structure is discussed.
文摘Biliary tract cancer(BTC)is a group of heterogeneous sporadic diseases,including intrahepatic,hilar,and distal cholangiocarcinoma,as well as gallbladder cancer.BTC is characterized by high invasiveness and extremely poor prognosis,with a global increased incidence due to intrahepatic cholangiocarcinoma(ICC).The 18Ffludeoxyglucose positron emission tomography(PET)computed tomography(18F-FDG PET/CT)combines glucose metabolic information(reflecting the glycolytic activity of tumor cells)with anatomical structure to assess tumor metabolic heterogeneity,systemic metastasis,and molecular characteristics noninvasively,overcoming the limitations of traditional imaging in the detection of micrometastases and recurrent lesions.18F-FDG PET/CT offers critical insights in clinical staging,therapeutic evaluation,and prognostic prediction of BTC.This article reviews research progress in this field over the past decade,with a particular focus on the advances made in the last 3 years,which have not been adequately summarized and recognized.The research paradigm in this field is shifting from qualitative to quantitative studies,and there have been significant breakthroughs in using 18F-FDG PET/CT metabolic information to predict gene expression in ICC.Radiomics and deep learning techniques have been applied to ICC for prognostic prediction and differential diagnosis.Additionally,PET/magnetic resonance imaging is increasingly demonstrating its value in this field.
文摘AIM:To investigate the value of optical coherence tomography angiography(OCTA)indicators in the diagnosis of diabetic retinopathy(DR),and to provide patients with diabetic nephropathy(DN)with more sensitive OCTA screening indicators to detect concurrent DR at an early stage.METHODS:A total of 200 patients who treated in the ophthalmology department of the Seventh Affiliated Hospital,Sun Yat-sen University from 2022 to 2023 were included,including 95 first-diagnosed DR patients and 105 patients without DR,and all patients underwent OCTA examination and a collection of demographics and renal function parameters.After a quality check,automated measurements of the foveal avascular zone area,vessel density(VD),and perfusion density(PD)of both 3 mm×3 mm and 6 mm×6 mm windows were obtained.RESULTS:Using random forest and multivariate Logistic regression methods,we developed a diagnostic model for DR based on 12 variables(age,FBG,SBP,DBP,HbA1c,ALT,ALP,urea/Scr,DM duration,HUA,DN,and CMT).Adding specific OCTA parameters enhanced the efficacy of the existing diagnostic model for DR(outer vessel density in 6 mm×6 mm window,AUC=0.837 vs 0.819,P=0.03).In the study of DN patients,the parameters in the 6 mm×6 mm window improved the diagnostic efficacy of DR(inner VD;outer VD;full VD;outer PD;full PD).CONCLUSION:The outer VD in the 6 mm×6 mm window can enhance the efficacy of the traditional DR diagnostic model.Meanwhile,compared with the 3 mm×3 mm window,the microvascular parameters in the 6 mm×6 mm window focusing on DN patients can be more sensitive to diagnosing the occurrence of DR.
基金supported by the Research Project of the Shanghai Health Commission,No.2020YJZX0111(to CZ)the National Natural Science Foundation of China,Nos.82021002(to CZ),82272039(to CZ),82171252(to FL)+1 种基金a grant from the National Health Commission of People’s Republic of China(PRC),No.Pro20211231084249000238(to JW)Medical Innovation Research Project of Shanghai Science and Technology Commission,No.21Y11903300(to JG).
文摘Nowadays,presynaptic dopaminergic positron emission tomography,which assesses deficiencies in dopamine synthesis,storage,and transport,is widely utilized for early diagnosis and differential diagnosis of parkinsonism.This review provides a comprehensive summary of the latest developments in the application of presynaptic dopaminergic positron emission tomography imaging in disorders that manifest parkinsonism.We conducted a thorough literature search using reputable databases such as PubMed and Web of Science.Selection criteria involved identifying peer-reviewed articles published within the last 5 years,with emphasis on their relevance to clinical applications.The findings from these studies highlight that presynaptic dopaminergic positron emission tomography has demonstrated potential not only in diagnosing and differentiating various Parkinsonian conditions but also in assessing disease severity and predicting prognosis.Moreover,when employed in conjunction with other imaging modalities and advanced analytical methods,presynaptic dopaminergic positron emission tomography has been validated as a reliable in vivo biomarker.This validation extends to screening and exploring potential neuropathological mechanisms associated with dopaminergic depletion.In summary,the insights gained from interpreting these studies are crucial for enhancing the effectiveness of preclinical investigations and clinical trials,ultimately advancing toward the goals of neuroregeneration in parkinsonian disorders.
文摘BACKGROUND Atypical optic neuritis,consisting of neuromyelitis optica spectrum disorders(NMOSD)or myelin oligodendrocyte glycoprotein antibody disease(MOGAD),has a very similar presentation but different prognostic implications and longterm management strategies.Vascular and metabolic factors are being thought to play a role in such autoimmune neuro-inflammatory disorders,apart from the obvious immune mediated damage.With the advent of optical coherence tomography angiography(OCTA),it is easy to pick up on these subclinical macular microvascular and structural changes.AIM To study the macular microvascular and structural changes on OCTA in atypical optic neuritis.METHODS This observational cross-sectional study involved 8 NMOSD and 17 MOGAD patients,diagnosed serologically,as well as 10 healthy controls.Macular vascular density(MVD)and ganglion cell+inner plexiform layer thickness(GCIPL)were studied using OCTA.RESULTS There was a significant reduction in MVD in NMOSD and MOGAD affected as well as unaffected eyes when compared with healthy controls.NMOSD and MOGAD affected eyes had significant GCIPL thinning compared with healthy controls.NMOSD unaffected eyes did not show significant GCIPL thinning compared to healthy controls in contrast to MOGAD unaffected eyes.On comparing NMOSD with MOGAD,there was no significant difference in terms of MVD or GCIPL in the affected or unaffected eyes.CONCLUSION Although significant microvascular and structural changes are present on OCTA between atypical optic neuritis and normal patients,they could not help in differentiating between NMOSD and MOGAD cases.
基金supported by the National Natural Science Foundation of China(41830103)the Project of Nanjing Center of China Geological Survey(DD20190281).
文摘Dense-array ambient noise tomography is a powerful tool for achieving high-resolution subsurface imag-ing,significantly impacting geohazard prevention and control.Conventional dense-array studies,how-ever,require simultaneous observations of numerous stations for extensive coverage.To conduct a comprehensive karst feature investigation with limited stations,we designed a new synchronous-asyn-chronous observation system that facilitates dense array observations.We conducted two rounds of asynchronous observations,each lasting approximately 24 h,in combination with synchronous backbone stations.We achieved wide-ranging coverage of the study area utilizing 197 nodal receivers,with an average station spacing of 7 m.The beamforming results revealed distinct variations in the noise source distributions between day and night.We estimated the source strength in the stationary phase zone and used a weighting scheme for stacking the cross-correlation functions(C ^(1) functions)to suppress the influ-ence of nonuniform noise source distributions.The weights were derived from the similarity coefficients between multicomponent C^(1)functions related to Rayleigh waves.We employed the cross-correlation of C ^(1) functions(C^(2)methods)to obtain the empirical Green’s functions between asynchronous stations.To eliminate artifacts in C ^(2) functions from higher-mode surface waves in C^(1)functions,we filtered the C^(1)functions on the basis of different particle motions linked to multimode Rayleigh waves.The dispersion measurements of Rayleigh waves obtained from both the C^(1)and C^(2)functions were utilized in surface wave tomography.The inverted three-dimensional(3D)shear-wave(S-wave)velocity model reveals two significant low-velocity zones at depths ranging from 40 to 60 m,which align well with the karst caves found in the drilling data.The method of short-term synchronous-asynchronous ambient noise tomography shows promise as a cost-effective and efficient approach for urban geohazard investigations.
基金Supported by the Health Commission of the Sichuan Province Medical Science and Technology Program,China,No.24WXXT10the Sichuan Province Science and Technology Support Program,China,No.2021YJ0242the 23rd Batch of Student Scientific Research Project Approval of Jiangsu University,China,No.Y23A164.
文摘Pericoronary adipose tissue(PCAT)plays an important role in the pathogenesis and progression of cardiovascular diseases due to its bidirectional communication with the coronary artery wall.In recent years,PCAT parameters measured using coronary computed tomography have emerged as potential noninvasive imaging biomarkers for quantifying coronary artery inflammation,with significant clinical value in the early detection,disease progression assessment,treatment efficacy evaluation,and prognosis prediction of cardiovascular diseases.Furthermore,new technologies such as PCAT radiomics analysis have broadened its potential applications in evaluating coronary plaque vulnerability,predicting cardiovascular events,and improving risk stratification.This review discusses recent advances in PCAT research,focusing on its role in coronary artery disease risk identification and inflammation monitoring,and aims to offer imaging-based insights to support its future clinical use in cardiovascular disease management.
文摘Angiomyolipomas(AMLs)represent the most common benign solid renal tumors.The frequency of their detection in the general population is increasing owing to advances in imaging technology.The objective of this review is to discuss computed tomography(CT)and magnetic resonance imaging findings for both typical and atypical renal AMLs,along with their associated complications.AMLs are typically defined as solid triphasic tumors composed of varying amounts of dysmorphic and tortuous blood vessels,smooth muscle components and adipose tissue.In an adult,a classical renal AML appears as a solid,heterogeneous renal cortical mass with macroscopic fat.However,up to 5%of AMLs contain minimal fat and cannot be reliably diagnosed by imaging.Fat-poor AMLs can appear as hyperattenuating masses on unenhanced CT and as hypointense masses on T2WI;other AMLs may be isodense or exhibit cystic components.Hemorrhage is the most common complication,and AMLs with hemorrhage can mimic other tumors,making their diagnosis challenging.Understanding the variable and heterogeneous nature of this neoplasm to correctly classify renal AMLs and to avoid misdiagnosis of other renal lesions is crucial.
基金Funded by Chinese National Natural Science Foundation of China(No.U2006224)。
文摘The paper presents experimental investigation results of crack pattern change in cement pastes caused by external sulfate attack(ESA).To visualize the formation and development of cracks in cement pastes under ESA,an X-ray computed tomography(X-ray CT)was used,i e,the tomography system of Zeiss Xradia 510 versa.The results indicate that X-CT can monitor the development process and distribution characteristics of the internal cracks of cement pastes under ESA with attack time.In addition,the C3A content in the cement significantly affects the damage mode of cement paste specimens during sulfate erosion.The damage of ordinary Portland cement(OPC)pastes subjected to sulfate attack with high C3A content are severe,while the damage of sulfate resistant Portland cement(SRPC)pastes is much smaller than that of OPC pastes.Furthermore,a quadratic function describes the correlation between the crack volume fraction and development depth for two cement pastes immermed in sulfate solution.
