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IMMEDIATE BREAST RECONSTRUCTION WITH LATISSIMUS DORSI MUSCULOCUTANEOUS FLAP: A SUITABLE OPTION FOR CHINESE WOMEN AFTER MASTECTOMY
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作者 狄根红 余科达 +4 位作者 吴炅 亓发芝 陆劲松 沈镇宙 邵志敏 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2006年第2期88-93,共6页
Objective: To discuss the suitable immediate breast reconstruction modalities for Chinese patients by comparing the pedicled transverse rectus abdominis myocytaneous flap (TRAM) reconstruction with latissimus dorsi... Objective: To discuss the suitable immediate breast reconstruction modalities for Chinese patients by comparing the pedicled transverse rectus abdominis myocytaneous flap (TRAM) reconstruction with latissimus dorsi myocytaneous flap (LTD) reconstruction plus implants or not after mastectomy due to breast cancer. Methods: From Jan. 2000 to Jul. 2005, 74 staged 0-II patients (mean age 39) were performed immediate breast reconstruction with autologous tissue either using LTD flaps or pedicled TRAM flaps with supplemental implants when necessary after mastectomy due to breast cancer and the charts were reviewed. Results: The age, marriage and menses status did not affect the selection of modalities and the need of implants. In 74 patients, 62 cases (83.8%) were performed LTD reconstruction with 13 implants and 12 cases received TRAM with 1 implant. The difference in need of implants or not between the two modalities had no statistical significance (P=0.442, Fisher' exact test). Aesthetic results judged as good or fair were in 88% patients and the cosmetic effects between LTD and TRAM groups or implant and non-implant groups had no differences. All reconstructions were successful, with 4.1% cumulative locoregional recurrence and 100% overall survival by following up to 66 months (median 9 months). The DFS and RFS between the two modalities had no significant differences by log rank test. Conclusion: Immediate autologous tissue reconstruction makes it possible to regain the natural and symmetric contour of breast without increased local recurrence. The LTD flap reconstruction is a suitable option for most Chinese women as well as the pedicled TRAM flap. 展开更多
关键词 Breast neoplasms Surgery Plastic MAMMAPLASTY IMMEDIATE Latissimus dorsi myocytaneous flap
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Male papillary breast cancer treated by wide resection and latissimus dorsi flap reconstruction: A case report and review of the literature
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作者 Malgorzata Banys-Paluchowski Eike Burandt +4 位作者 Joanna Banys Stefan Geist Guido Sauter Natalia Krawczyk Peter Paluchowski 《World Journal of Clinical Oncology》 CAS 2016年第5期420-424,共5页
Breast cancer(BC) in men represents between 0.5% and 1% of all BC diagnosed each year. We report a case of advanced BC in a 62-year-old male treated at our interdisciplinary Breast Cancer Center. The patient presented... Breast cancer(BC) in men represents between 0.5% and 1% of all BC diagnosed each year. We report a case of advanced BC in a 62-year-old male treated at our interdisciplinary Breast Cancer Center. The patient presented with a newly diagnosed large, symptomatic mass in his left breast. Clinical examination showed a not movable mass of 16 cm diameter, deforming the whole breast; the overlying skin was livid and hypervascularized. Enlarged lymph nodes were palpable in the axillary pit. He had no concomitant diseases at time of presentation. He denied any first- or second degree family medical history of cancer of any type and he never received radiotherapy. Ultrasound guided minimal-invasive 14-gauge core biopsy revealed a moderately differentiated encapsulated papillary carcinoma with high expression of estrogen and progesterone receptors(both > 80%, IRS 12) and HER2-negative. Because of the tumor size a mastectomy with axillary dissection and chest wall reconstruction using a latissimus dorsi flap was performed. Histological analysis showed invasive growth besides typical(non-invasive) papillary carcinoma and was classified as invasive solid papillary carcinoma; p T3(10 cm), p N0(0/15), M0,R0; Oncotype DX Recurrence Score indicated low risk(RS: 2). After discussion in the interdisciplinary tumor board meeting, radiation therapy and tamoxifen were recommended. The patient had an uneventful recovery and is disease-free after two years of follow-up. Male BC is typically diagnosed at an advanced stage, most likely due to a lack of awareness that men can develop BC. Therefore, in case of a large tumor, a flap-based thoracic reconstruction may be required. 展开更多
关键词 MALE BREAST cancer PAPILLARY carcinoma Reconstruction Latissimus dorsi FLAP RARE TUMORS
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Pre-expanded Muscle-sparing Latissimus Dorsi Flaps for Reconstruction of Severe Scar Contractures on the Anterior Chest 被引量:1
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作者 Zhichao WANG Dujuan LIU +3 位作者 Shuchen GU Baoxiang TIAN Tao ZAN Bin GU 《Chinese Journal of Plastic and Reconstructive Surgery》 2020年第2期63-68,77,共7页
Objective To investigate the utility of pre-expanded muscle-sparing latissimus dorsi flaps in the reconstruction of deformities secondary to severe scar contractures on the anterior chest.Methods The function of the l... Objective To investigate the utility of pre-expanded muscle-sparing latissimus dorsi flaps in the reconstruction of deformities secondary to severe scar contractures on the anterior chest.Methods The function of the latissimus dorsi was preserved with blood supply from the main or lateral branch of the thoracodorsal artery.The entire treatment period was divided into two stages,during which segmental latissimus dorsi flaps were pre-expanded in stage I and anterior chest scar deformities were reconstructed in stage II.During stage I,the musculocutaneous perforators arising from the lateral branch of the thoracodorsal artery were determined by ultrasound preoperatively;the flap design included the anterior segment of the latissimus dorsi supplied by the musculocutaneous perforators from the lateral branch;and a tissue expander was placed following flap dissection and then infused with saline intermittently for 4–6 months.In stage II,the chest scars were excised,and breast tissues were repositioned;the continuity of the medial branch of the thoracodorsal nerve to the muscle was preserved when reconstruction was performed using the segmental latissimus dorsi flaps supplied by the main or lateral branch of the thoracodorsal artery.Results From October 2010 to October 2019,21 patients(on 24 sides)underwent reconstructive procedures for extensive scar contractures on the anterior chest.All flaps survived,and their donor sites were sutured directly.During a follow-up of 3 months to 8 years,the flaps became soft and exhibited color similar to that of the adjacent tissues.The limited neck and shoulder movements improved,and postoperatively,all female patients were satisfied with the shape of their breasts.Additionally,neither apparent weakening on the adduction,internal rotation,or extension strength of the shoulder joint on the affected side nor marked depression deformity in the back was observed.Conclusion Pre-expanded muscle-sparing latissimus dorsi flaps with blood supply from the main or lateral branch of the thoracodorsal artery proved to be a desirable option for the reconstruction of extensive scar contractures on the anterior chest. 展开更多
关键词 Latissimus dorsi flaps pre-expansion muscle-sparing thoracic scars
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Intrathoracic latissimus dorsi muscle transposition: a reliable technique for prevention of bronchopleural fistula developing after extrapleural pneumonectomy and external beam radiotherapy in malignant pleural mesothelioma
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作者 MagedM.Elshafiey HishamA.El-hossieny IsmailA.Mourad 《The Chinese-German Journal of Clinical Oncology》 CAS 2012年第7期373-379,共7页
Objective: Bronchopleural fistula (BPF) is a life threatening complication after pneumonectomy. Extra thoracic skeletal muscle transposition especially latissimus dorsi muscle flap (LDMF) had been used to prevent this... Objective: Bronchopleural fistula (BPF) is a life threatening complication after pneumonectomy. Extra thoracic skeletal muscle transposition especially latissimus dorsi muscle flap (LDMF) had been used to prevent this complication. The aim of this study was to assess the effectiveness of LDMF in preventing BPF developing after extrapleural pneumonectomy (EPP) and external radiation therapy in malignant pleural mesothelioma (MPM). Methods: Between May 1999 and Dec. 2008, 37 patients with MPM were operated upon by EPP using LDMF prophylactically to reinforce the bronchial stump, and then received external radiation therapy with or without postoperative chemotherapy. Results: The mean age of all patients was 46.7 (range 26-57) years. Twenty five patients were males and 12 patients were females. Twenty three patients had MPM of the right side and 14 patients had MPM of the left side. The peri-operative mortality was 2.7% and only few flap related postoperative morbidity were reported in the form of minor seroma and subcutaneous surgical emphysema. The median follow up was 17 (range 9-43) months. All cases completed their postoperative external radiation therapy with no reported cases of early or late BPF. Conclusion: Intrathoracic pedicled LDMF transposition is proved to be effective in prevention of BPF developing after EPP and external radiation therapy in MPM and it is advised to be a routine step in EPP in these cases and to use more sophisticated technique of postoperative external beam radiotherapy (3D conformal or IMRT) to minimize this complication. 展开更多
关键词 malignant pleural mesothelioma (MPM) extrapleural pneumonectomy (EPP) latissimus dorsi muscle flap(LDMF) bronchopleural fistula (BPF)
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Latissimus Dorsi Mini-Flap as a Volume Replacement Technique after Partial Mastectomy for Breast Cancer in the Upper and Central Breast Quadrants: A Single Center Experience
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作者 Waleed Elnahas Ashraf Khater +3 位作者 Mohamed Hamdy Emadeldeen Hamed Osama Eldamshety Mohamed Hegazy 《Surgical Science》 2016年第11期496-504,共9页
Background: The latissimus dorsi (LD) muscle flap plays an essential role in breast reconstruction after partial mastectomy for cancer because of its stability and versatility. We evaluated both oncologic and aestheti... Background: The latissimus dorsi (LD) muscle flap plays an essential role in breast reconstruction after partial mastectomy for cancer because of its stability and versatility. We evaluated both oncologic and aesthetic outcomes in addition to the related complications of this flap as an adjunct to breast conserving surgery in the management of breast cancer patients. Methods: All patients underwent a one-stage procedure with immediate reconstruction through two-steps operation;wider local excision utilizing oncoplastic principles and mini flap harvest & volume replacement. Results: The study included 34 cases with early breast cancer;30 patients had partial breast resection and defect refilling by LD mini-flap, three patients underwent mastectomy and one patient underwent extended LDF. The mean defect volume was (212.63 cm<sup>3</sup> ± 59.57) cm<sup>3</sup>, while the mean flap volume was (218.27 cm<sup>3</sup> ± 53.64 cm<sup>3</sup>). Patient self-evaluation of the cosmetic outcome was excellent in 20%, good in 60% and satisfactory in 20% of patients. Panel evaluation according to Harvard scale showed excellent in 36.7%, good in 36.7%, fair in 26.7% of patients. The median hospital stay was 4 days. The postoperative complications included wound gap in 4 patients (13.3%), postoperative donor site seroma in 16 patients (53.3%). No flap loss or necrosis, no affection on arm or shoulder mobility occurred. Lastly, no tumor recurrence till now. Conclusion: Latissimus dorsi mini-flap can achieve adequate cosmetic and oncologic outcomes with a low incidence of complications in patients with early stage (I/II) breast cancer and small to medium sized breasts. 展开更多
关键词 ONCOPLASTIC Breast Surgery Latissimus dorsi Mini-Flap Conservative Surgery
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Natural History of Seroma Following the Immediate Latissimus Dorsi Flap Method of Breast Reconstruction 被引量:3
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作者 Wen-Hui Yan Jian-Bo Mang +1 位作者 Li-Li Ren Da-Lie Liu 《Chinese Medical Journal》 SCIE CAS CSCD 2018年第14期1674-1679,共6页
Background: The latissimus dorsi (LD) flap procedure remains a popular and useful breast reconstrtlction tool in China and Western countries, and donor site seroma formation is the main complication. This study was... Background: The latissimus dorsi (LD) flap procedure remains a popular and useful breast reconstrtlction tool in China and Western countries, and donor site seroma formation is the main complication. This study was conducted in Chinese patients to determine whether stable cases of seromas would resolve without treatment. Methods: A retrospective review of 45 consecutive cases of immediate breast reconstruction with LD flap from April 2012 to February 2017 was conducted. The scope of the seroma was demarcated with a marker pen, and cases that remained stable over time (i.e. the size of the seroma did not increase) were observed without treatment. The measured outcomes included the incidence ofseromas, the volume and duration of postoperative wound drainage, and other demographic characteristics. Results: Twenty-four patients (53.3%) developed a seroma at the donor site. Of these, 21 patients (87.5%) did not require treatment, and the seroma resolved over time. The mean duration of a sustained serol-na was 6.8 ± 1.4 weeks (range: 4-9 weeks). Conclusions: This study observed the scope and progression of the seromas and found that seromas at the LD donor sites resolved over time without treatnlent. 展开更多
关键词 Autologous Breast Reconstruction Breast Reconstruction Latissimus dorsi Myocutaneous Flap Observation: Seroma
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Meridian-like character of reflex electromyogram activity in longissimus dorsi muscles 被引量:1
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作者 Chao Ma Zheng Zheng Yikuan Xie 《Chinese Science Bulletin》 SCIE EI CAS 2001年第1期57-62,共6页
We studied the temporal and spacial character of the electromyogram (EMG) evoked by acupuncture in long-issimus dorsi (LD) muscles of rat, and evaluated the effect of needling direction or local blockade on EMG propag... We studied the temporal and spacial character of the electromyogram (EMG) evoked by acupuncture in long-issimus dorsi (LD) muscles of rat, and evaluated the effect of needling direction or local blockade on EMG propagation. When certain sites on LD muscle were acupunctured, asynchronous EMG could be activated not only at the acupunctured point, but also within the muscle region supplied by the adjacent 2-3 vertebral segments. The EMG evoked by stimulation on the borderline of aponeurosis and muscle venter was larger in amplitude than those on the other sites in the same vertebral segment. When the distance from the recorded site to stimulated site increased, the EMG amplitude decreased, and its latency prolonged. Acupuncture in an oblique direction toward rostral or caudal side of the muscle enhanced the EMG amplitude in the same direction. EMG activity was weakened and its propagation was blocked by local injection of procaine. These results indicated that the character of EMG propagation evoked by 展开更多
关键词 longissimus dorsi muscle REFLEX ELECTROMYOGRAM ACTIVITY acupuncture needle-feeling propagation.
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背阔肌KISS皮瓣在巨大乳腺肿瘤切除术后创面修复中的临床效果
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作者 饶彬 吴耀忠 +4 位作者 霍培成 董安慧 黄汶文 卢杰明 覃高升 《临床医学研究与实践》 2026年第2期49-52,共4页
目的探讨背阔肌KISS皮瓣在巨大乳腺肿瘤切除术后创面修复中的临床效果。方法回顾性分析2022年1月至2023年6月在梧州市红十字会医院乳腺外科接受巨大乳腺肿瘤切除术并采用背阔肌KISS皮瓣修复创面的20例女性患者的临床资料。术后对所有患... 目的探讨背阔肌KISS皮瓣在巨大乳腺肿瘤切除术后创面修复中的临床效果。方法回顾性分析2022年1月至2023年6月在梧州市红十字会医院乳腺外科接受巨大乳腺肿瘤切除术并采用背阔肌KISS皮瓣修复创面的20例女性患者的临床资料。术后对所有患者随访6个月,评价手术相关情况、术后美容效果及创面愈合情况。结果20例患者中,肿瘤最小面积为8 cm×8 cm,最大面积为16 cm×15 cm;切除术后缺损和背阔肌皮瓣最小面积均为12 cm×10 cm,最大面积均为18 cm×13 cm。手术效果达到优良者共18例(90.00%),术后发生并发症5例(25.00%),术后肿瘤复发3例(15.00%),术后肩关节功能正常16例(80.00%)。术后美容效果评价中非常满意11例(55.00%),比较满意6例(30.00%),不太满意2例(10.00%),不满意1例(5.00%)。创面一期愈合率为80.00%(16/20)。结论背阔肌KISS皮瓣具有血供丰富、切取方便、操作简单及供区隐蔽等优势,能够有效提高皮瓣成活率,促进创面良好愈合,并获得较高的外观满意度,可作为巨大乳腺肿瘤切除术后大面积皮肤缺损的优选修复方法。 展开更多
关键词 背阔肌KISS皮瓣 巨大乳腺肿瘤 创面修复
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Application of three-dimensional digitalized reconstruction of latissimus dorsi myocutaneous flap
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作者 Yuanzhi ZHANG Jianwei LI +4 位作者 Yanbing LI Dan JIN Jionghao CHEN Shizhen ZHONG Guoxian PEI 《Frontiers of Medicine》 SCIE CSCD 2008年第1期45-50,共6页
Developments of digital technology and three-dimensional(3D)reconstruction allowed a precise description of anatomic structures.With the introduction of Visible Human Project and Virtual Chinese Human(VCH)techniques,m... Developments of digital technology and three-dimensional(3D)reconstruction allowed a precise description of anatomic structures.With the introduction of Visible Human Project and Virtual Chinese Human(VCH)techniques,more detailed anatomic images could be obtained.Digitized visible models of these structures can be applied as a useful tool in clinical training.The aim of this study was to reconstruct the normal structures of thoracodorsal artery in 3D images and to establish the digitized visible models of latissimus dorsi myocutaneous(LDM)flap.The cross-sectional images from the four VCH datasets were reviewed to study LDM and thoraco-dorsal artery structures on a section-by-section basis.Next,two adult fresh cadaver specimens were perfused with lead oxide-gelatine mixture and subject to radio-graphic CT scanning on their torsos.The cross-sectional images from the CT images were reviewed to study thor-acodorsal artery structures.Three-dimensional computer-ized reconstructions of LDM flap structures were conducted from these datasets by using Amira 3.1(TGS)software respectively.The 3D reconstructed visible models established from these datasets perfectly displayed the anatomic characteristics of LDM flap. 展开更多
关键词 latissimus dorsi myocutaneous IMAGING THREE-DIMENSIONAL Virtual Chinese Human digital technique
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Defect reconstruction of the trochanter major after necrotizing fasciitis and multiple operations using an arteriovenous Ioop and Iatissimus dorsi free flap
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作者 Andreas Arkudas Susanne Regus +3 位作者 Alexander Meyer Werner Lang Marweh Schmitz Raymund E.Horch 《Plastic and Aesthetic Research》 2018年第9期40-45,共6页
Necrotizing fasciitis (NF) is a severe soft tissue infection which has to be treated with a radical debridement as the key element. In the further course often large tissue defects occur, so that a long-term stable de... Necrotizing fasciitis (NF) is a severe soft tissue infection which has to be treated with a radical debridement as the key element. In the further course often large tissue defects occur, so that a long-term stable defect reconstruction plays a crucial role after any successful debridement. The reconstruction can include split skin grafting or local and free flaps. Here we present a case of a 41-year-old male patient with a NF in the trochanter major region after spondylodesis and spinal cord stimulation (SCS) device implantation. After multiple operations including local and free flaps we performed a defect reconstruction using an arteriovenous (AV) loop and subsequent free latissimus dorsi transplantation leading to no further operations. This complex reconstruction can be considered as the final stage of any reconstruction latter. 展开更多
关键词 NECROTIZING FASCIITIS ARTERIOVENOUS LOOP free Iatissimus dorsi FLAP TRANSPLANTATION
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Reverse latissimus dorsi muscle flap for complex back defects: our experience
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作者 Kumaraswamy Mohan Kumar Shantha Kumar Shivalingappa +1 位作者 Veena Prabhakar Waiker Udaya Shankar Odeyar 《Plastic and Aesthetic Research》 2017年第5期76-81,共6页
Aim: The aim was to study the effectiveness of the reverse latissimus dorsi muscle flap in reconstruction of complex defects of the back. Methods: This is a retrospective study of patients who underwent reverse latiss... Aim: The aim was to study the effectiveness of the reverse latissimus dorsi muscle flap in reconstruction of complex defects of the back. Methods: This is a retrospective study of patients who underwent reverse latissimus dorsi flap for reconstruction of the back, in a tertiary care hospital. The patient demographics, etiology, surgery indications and complications were studied. Results: The study had five patients between 2012 and 2016 who underwent reverse latissimus dorsi flap for reconstruction. The flaps survived in all the patients. Two patients had complications, unrelated to the latissimus dorsi muscle flap. Conclusion: The vascularity of the flap is reliable can be used to obliterate the dead space, can be used to control the infection, in complex cases of the back. 展开更多
关键词 REVERSE latissimus dorsi muscle FLAP COMPLEX BACK DEFECTS REVERSE TURN over FLAP
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Reverse bilateral latissimus dorsi flap reconstruction after extensive mid back dermatofibrosarcoma protuberans excision:a case report
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作者 Stefano Bonomi Laura Sala +2 位作者 Alessandro Gronchi Dario Callegaro Umberto Cortinovis 《Plastic and Aesthetic Research》 2018年第3期1-8,共8页
Surgical resection of soft tissue sarcoma of the trunk can result in large defects requiring complex reconstruction for coverage of vital neurovascular structures and tissue defect. Large defects of the back could be ... Surgical resection of soft tissue sarcoma of the trunk can result in large defects requiring complex reconstruction for coverage of vital neurovascular structures and tissue defect. Large defects of the back could be reconstructed with multiple random pattern or local pedicled flaps. We present the case of a 48-year-old patient with a locally advanced dermatofibrosarcoma protuberans of the back. Wide local excision of the lesion was performed. The soft tissue defect measured 22 cm × 20 cm × 4 cm and was reconstructed with bilateral reverse latissimus dorsi myocutaneous (RLDM) flap. Each RLDM flap measured 24 cm × 10 cm. The donor site on the back was closed directly on both sides. The patient recovered well and the two flaps healed uneventfully. Twelve months after surgery the patient is disease-free. The use of a RLDM flap in mid-back reconstructions provided wide well-vascularized soft tissue, minimized risk of infection, and maximized back coverage. This flap is an excellent choice for reconstruction of large defects of the mid-back. 展开更多
关键词 REVERSE latissimus dorsi myocutaneous flap TRUNK reconstruction posterior TRUNK defect SARCOMA DERMATOFIBROSARCOMA protuberans
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Revisiting pedicled latissimus dorsi flaps in head and neck reconstruction:contrasting shoulder morbidities across mysofascial flaps
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作者 Allen L.Feng Hassan B.Nasser +6 位作者 Andrew J.Rosko Keith A.Casper Kelly M.Malloy Chaz L.Stucken Mark E.Prince Steven B.Chinn Matthew E.Spector 《Plastic and Aesthetic Research》 2021年第1期306-315,共10页
Free tissue transfer has become the gold standard for reconstruction within the head and neck.However,there are still many instances where pedicled locoregional flaps are the optimal reconstructive option.When myofasc... Free tissue transfer has become the gold standard for reconstruction within the head and neck.However,there are still many instances where pedicled locoregional flaps are the optimal reconstructive option.When myofascial tissue is needed,several options have been described throughout the literature.Various trapezius flaps have been used,although these have variable vascular anatomy and significant donor site morbidity.The pectoralis major myofascial flap has become a mainstay in head and neck reconstruction for its ease of harvest and reliability but suffers from similar issues with donor site morbidity.The pedicled latissimus dorsi flap(PLDF)is another reliable option that has been used for multiple different ablative sites within the head and neck.The thin,pliable structure of the latissimus dorsi makes it a viable option for many defects,and recent reports also support its feasibility for use in an interdisciplinary two-team approach.Furthermore,the donor site morbidity of the PLDF is minimal compared to other similar myofascial options.In this article,we describe the surgical considerations and operative techniques for PLDF transfer along with a review of its associated donor site morbidity. 展开更多
关键词 Pedicled latissimus dorsi flap surgical flaps myofascial flap head and neck reconstruction
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Pre-expanded muscle-sparing latissimus dorsi flap in defect reconstruction and its application strategy
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作者 Yashan Gao En Yang +7 位作者 Shenying Luo Xin Huang Yi Min Khoong Shuchen Gu Yunhan Liu Wenzheng Xia Haizhou Li Tao Zan 《Burns & Trauma》 2024年第1期611-613,共3页
To the editor In 2003,Schwabegger et al.proposed the muscle-sparing latissimus dorsi(MS-LD)flap[1],which preserved a portion of the latissimus dorsi(LD)muscle around the point where the thoracodorsal artery(TDA)perfor... To the editor In 2003,Schwabegger et al.proposed the muscle-sparing latissimus dorsi(MS-LD)flap[1],which preserved a portion of the latissimus dorsi(LD)muscle around the point where the thoracodorsal artery(TDA)perforator penetrates the muscle,having the advantages of a sufficient flap blood supply and reduced donor-site morbidity.However,the traditional MS-LD flap is still too bulky for the reconstruction of defects of the face and neck,and the size of the traditional flap is sometimes not enough to repair large defects.Thus,combining soft tissue expansion with a vascular supercharging technique,we propose a novel design of MS-LD flap,as well as its application strategy. 展开更多
关键词 muscle sparing latissimus dorsi flap reconstruction defects repair l soft tissue expansion vascular supercharging face neck defect reconstruction
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游离背阔肌双叶kiss皮瓣修复巨大软组织恶性肿瘤切除术后创面缺损病案报道并文献复习
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作者 张宏 邵蓉 +1 位作者 王军 范向达 《中国医药科学》 2025年第16期177-180,共4页
近年来,软组织恶性肿瘤的发病率逐年上升,对于下肢的巨大软组织恶性肿瘤首选手术治疗,而切除术后引起的巨大缺损常无法直接拉拢缝合,采用邻近皮瓣转移的方法常无法满足要求,需要面积大的皮瓣才能修复,随着显微技术的发展,游离皮瓣在临... 近年来,软组织恶性肿瘤的发病率逐年上升,对于下肢的巨大软组织恶性肿瘤首选手术治疗,而切除术后引起的巨大缺损常无法直接拉拢缝合,采用邻近皮瓣转移的方法常无法满足要求,需要面积大的皮瓣才能修复,随着显微技术的发展,游离皮瓣在临床中的应用越来越多,其中使用较多的有游离股前外侧皮瓣、游离前臂皮瓣、游离腹壁下动脉皮瓣、游离上臂皮瓣、游离背阔肌皮瓣等,游离皮瓣可完全解决邻近皮瓣转移受限的问题,游离背阔肌皮瓣可提供较大的组织量,根据胸背动脉的解剖及走形,背阔肌皮瓣可制备成一蒂双岛,对于创面较大的缺损常常能得到很好的修复,且供区可一期拉拢缝合,对供区功能影响小,值得在临床大力推广。 展开更多
关键词 游离背阔肌 修复 下肢软组织恶性肿瘤 游离皮瓣 纤维肉瘤
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离断胸背血管桥支对重建乳房的影响
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作者 艾小红 李芳英 +3 位作者 艾一凡 王彦 蒲竞 赵鹏 《兰州大学学报(医学版)》 2025年第6期26-32,共7页
目的探讨背阔肌皮瓣一期乳房重建术中离断胸背血管桥支的应用价值。方法回顾性分析甘肃省白银市第一人民医院和甘肃省第三人民医院2020年5月—2023年3月,行保留乳头乳晕复合体乳腺癌改良根治术联用背阔肌皮瓣一期乳房重建术的80例乳腺... 目的探讨背阔肌皮瓣一期乳房重建术中离断胸背血管桥支的应用价值。方法回顾性分析甘肃省白银市第一人民医院和甘肃省第三人民医院2020年5月—2023年3月,行保留乳头乳晕复合体乳腺癌改良根治术联用背阔肌皮瓣一期乳房重建术的80例乳腺癌患者临床相关资料。根据术中对胸背血管桥支不同处理方式,分为试验组(41例)和对照组(39例),其中对照组保留胸背血管桥支,试验组为离断胸背部血管桥支1~2支。对比两组患者手术指标、乳房表面美观度评分、患者满意度、术后并发症状况,以及术前和术后6个月上肢活动度、生活质量(癌症患者生活质量量表)。结果试验组手术时间略短于对照组(P<0.05);与对照组(64.10%)相比,试验组患者满意度(85.37%)较高(P<0.05);两组患者术后并发症发生率差异无统计学意义(P>0.05);两组患者术前和术后6个月上肢活动度差异无统计学意义(P>0.05);试验组术后3、6个月的生活质量显著高于对照组(P<0.05)。结论行保留乳头乳晕复合体乳腺癌改良根治术联用背阔肌皮瓣一期乳房重建术的乳腺癌者,术中离断胸背部血管桥支,有助于缩短手术时间,提高乳房美观度、患者满意度和生活质量,且对上肢活动度基本无影响。 展开更多
关键词 乳腺癌 乳房重建 胸背血管桥支 满意度 背阔肌皮瓣
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脉冲电场辅助低温解冻对猪肉品质的影响 被引量:3
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作者 刘品品 周家华 +6 位作者 张超 王宝刚 石兴明 洪海强 王云香 徐冉冉 江利华 《食品工业科技》 CAS 北大核心 2025年第1期343-348,共6页
为研究脉冲电场(Pulsed Electric Field,PEF)辅助低温解冻对猪肉品质的影响,以猪背最长肌为原料,置于-18℃的冰箱中冷冻7 d,取出后分别在Control:4℃,0 kV,自然解冻;PEF解冻:P3(4℃,3 kV)、P5(4℃,5 kV)、P10(4℃,10 kV)。分析不同解冻... 为研究脉冲电场(Pulsed Electric Field,PEF)辅助低温解冻对猪肉品质的影响,以猪背最长肌为原料,置于-18℃的冰箱中冷冻7 d,取出后分别在Control:4℃,0 kV,自然解冻;PEF解冻:P3(4℃,3 kV)、P5(4℃,5 kV)、P10(4℃,10 kV)。分析不同解冻处理对猪肉解冻时间、色泽、质构、水分损失以及水分分布的影响。结果表明:PEF处理可以缩短解冻时间,改善猪肉质量。P10组相比于Control组猪肉的解冻时间缩短了44.4%;不同解冻处理对猪肉蒸煮损失的影响无显著差异(P>0.05);PEF解冻后猪肉的硬度显著低于Control组(P<0.05);PEF解冻可以降低猪肉表面色泽的劣变程度,减少肌肉微观结构损伤。综上,当解冻温度为4℃,脉冲电压为10 kV时,解冻时间最短,解冻损失最低,肉样状态更接近鲜样,品质更好。 展开更多
关键词 脉冲电场 猪背最长肌 解冻 品质 劣变
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不同生长阶段滩羊背最长肌转录组比较 被引量:2
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作者 杜佳文 任文义 +1 位作者 徐晓锋 张力莉 《中国畜牧兽医》 北大核心 2025年第3期1011-1021,共11页
【目的】本研究旨在挖掘影响不同生长阶段滩羊背最长肌脂肪沉积的差异基因。【方法】分别采集3、6、9月龄滩羊的背最长肌,提取RNA后构建文库。采用Illumian软件对数据进行过滤、质控、比对,使用HTSeq统计后以P adj(校正后的P值)<0.05... 【目的】本研究旨在挖掘影响不同生长阶段滩羊背最长肌脂肪沉积的差异基因。【方法】分别采集3、6、9月龄滩羊的背最长肌,提取RNA后构建文库。采用Illumian软件对数据进行过滤、质控、比对,使用HTSeq统计后以P adj(校正后的P值)<0.05和|log 2FoldChange|>1作为标准筛选差异表达基因,并对基因进行GO功能和KEGG通路富集分析,随机选取5个基因进行实时荧光定量PCR验证。【结果】与3月龄相比,6月龄筛选到129个差异表达基因(上调47个,下调82个);9月龄筛选到521个差异表达基因(上调119个,下调402个);与6月龄相比,9月龄筛选到207个差异表达基因(上调45个,下调162个)。GO功能富集结果显示,与3月龄相比,6月龄差异表达基因富集到花生四烯酸单加氧酶活性、磷酸甘油酸脱氢酶活性等过程;9月龄差异表达基因富集到胞质钙离子的正调控、多细胞生物发育的调控等过程;与6月龄相比,9月龄差异表达基因富集到细胞内钙介导的信号传导、脂质磷酸酶活性等过程。KEGG通路注释结果显示,与3月龄相比,6月龄差异表达基因主要富集在胆固醇代谢、氨基糖和核苷酸糖的代谢等信号通路;9月龄差异表达基因主要富集在细胞外基质受体相互作用、胰岛素抵抗等信号通路;与6月龄相比,9月龄差异表达基因主要富集在c-AMP信号通路、生长激素的合成、分泌和作用等信号通路。FGF 10、ADCY 7等5个基因的实时荧光定量PCR验证结果与转录组测序结果一致。【结论】通过对不同月龄滩羊的背最长肌进行转录组测序分析,筛选出FGF 10、STAR可作为3、6月龄滩羊背最长肌脂肪沉积调控的候选基因,ADCY 7、CNR 1作为6、9月龄滩羊背最长肌脂肪沉积调控的候选基因,PPARGC 1 A、SLC 2 A 4作为3、9月龄滩羊背最长肌脂肪沉积调控的候选基因。研究结果可为进一步探究不同生长阶段滩羊背最长肌脂肪沉积提供理论依据。 展开更多
关键词 滩羊 转录组 脂肪 背最长肌
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Fenton体系氧化诱导下猪肉蛋白质与脂质氧化作用及其对品质的影响研究 被引量:1
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作者 刘佳雯 杨柳 +2 位作者 谢心蕊 李保国 王欣 《农业机械学报》 北大核心 2025年第1期453-462,473,共11页
采用Fenton氧化体系(Fendon oxidation system,FOS)研究了不同氧化水平(0、1、5、10、20 mmol/L H_(2)O_(2))下猪背最长肌的蛋白质及脂质的氧化作用及其与品质指标、挥发性风味物质的相关性。结果表明,随氧化程度的升高,猪背最长肌的离... 采用Fenton氧化体系(Fendon oxidation system,FOS)研究了不同氧化水平(0、1、5、10、20 mmol/L H_(2)O_(2))下猪背最长肌的蛋白质及脂质的氧化作用及其与品质指标、挥发性风味物质的相关性。结果表明,随氧化程度的升高,猪背最长肌的离心损失率、蒸煮损失率、S23(自由水比例)、L^(*)、过氧化值(Peroxide value,POV)、TBARS(Thiobarbituric acid reactive substances)值、羰基含量等均显著增加,而a^(*)、b^(*)、硬度、咀嚼性、黏性、表面疏水性先增加后降低,S22(不易流动水比例)、巯基含量、弹性、回复性、内聚性均减小;典型挥发性化合物组成变化显著,二聚体(2-戊酮D、2-丁酮D)、杂环类化合物(2,6-二甲基吡嗪、吡啶)及酸类(乙酸)物质增多。相关性分析表明,肉品品质变化是脂质和蛋白交互氧化的结果,脂质和肌原纤维蛋白氧化进一步导致了样品保水性的降低,色泽、风味和质构的劣变。 展开更多
关键词 猪背最长肌 Fenton氧化体系 脂质氧化 蛋白氧化 品质 挥发性风味物
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腔镜与开放手术获取背阔肌用于乳房重建的比较研究 被引量:1
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作者 冯玉 罗桂林 +2 位作者 梁法清 张栋林 杜正贵 《中国普外基础与临床杂志》 2025年第3期293-299,共7页
目的对比经腋窝单切口腔镜下皮下腺体切除+腔镜下背阔肌切取即刻背阔肌植入乳房重建术(简称“腔镜组”)与开放手术切取背阔肌即刻背阔肌植入乳房重建术(简称“开放组”)患者的手术资料、安全性、美容学效果及生活质量。方法收集前瞻性... 目的对比经腋窝单切口腔镜下皮下腺体切除+腔镜下背阔肌切取即刻背阔肌植入乳房重建术(简称“腔镜组”)与开放手术切取背阔肌即刻背阔肌植入乳房重建术(简称“开放组”)患者的手术资料、安全性、美容学效果及生活质量。方法收集前瞻性维持数据库中2021年1月至2024年6月期间在四川大学华西医院及四川省第四人民医院行背阔肌乳房重建的患者,根据手术方式分为腔镜组和开放组,比较2组患者的基线资料、手术相关资料、术后并发症及患者报道结局量表(BREAST-Q量表)评分结果。结果共收集到73例患者,其中腔镜组23例、开放组50例,2组患者除开放组中T4分期者占比较腔镜组高(P<0.001)外,其他如年龄、身体质量指数、乳房下垂、肿瘤位置、肿瘤N分期、病理类型、辅助治疗等比较差异均无统计学意义(P>0.05)。腔镜组较开放组可以切取更长的背阔肌(P=0.002)。2组患者的总外科并发症、主要并发症、次要并发症及植入物相关并发症比较差异均无统计学意义(P>0.05),2组患者最常见的并发症均为背部积液,腔镜组5例(21.7%),开放组11例(22.0%);主要并发症在腔镜组中未出现,在开放组中2例出现(1例患者因背阔肌缺血坏死、1例患者因乳房感染而导致植入物取出)。腔镜组的切口总长度明显小于开放组(P<0.001),腔镜组患者乳房满意度(P=0.045)、背部满意度(P<0.001)及性生活健康(P=0.028)评分均显著高于开放组。随访期内,开放组中有3例(6.0%)患者出现远处转移(均为肺转移),腔镜组中未出现局部或区域复发、远处转移及乳腺癌特异性死亡。结论本研究结果提示,对于皮肤有侵犯而渴望乳房重建或假体重建失败(如皮瓣缺血坏死)患者,开放手术取背阔肌是值得选择的手术方式。但是对于不需要额外皮肤乳房重建的乳腺癌患者,腔镜下取背阔肌乳房重建在美容学效果方面存在较大优势,而且是安全、有效的。 展开更多
关键词 背阔肌 乳房重建 腔镜 开放手术
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