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A Bilinear Sparse Domination for the Maximal Calder´on Commutator with Rough Kernel
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作者 WANG Meizhong ZHAO Junyan 《数学进展》 北大核心 2025年第5期1059-1074,共16页
LetΩbe homogeneous of degree zero,integrable on S^(d−1) and have vanishing moment of order one,a be a function on R^(d) such that ∇a∈L^(∞)(R^(d)).Let T*_(Ω,a) be the maximaloperator associated with the d-dimensional... LetΩbe homogeneous of degree zero,integrable on S^(d−1) and have vanishing moment of order one,a be a function on R^(d) such that ∇a∈L^(∞)(R^(d)).Let T*_(Ω,a) be the maximaloperator associated with the d-dimensional Calder´on commutator defined by T*_(Ωa)f(x):=sup_(ε>0)|∫_(|x-y|>ε)^Ω(x-y)/|x-y|^(d+1)(a(x)-a(y))f(y)dy.In this paper,the authors establish bilinear sparse domination for T*_(Ω,a) under the assumption Ω∈L∞(Sd−1).As applications,some quantitative weighted bounds for T*_(Ω,a) are obtained. 展开更多
关键词 Calderon commutator Fourier transform multiplier operator approximation bilinear sparse domination rough kernel
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Dominating Induced Matching of Generalized Petersen Graphs
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作者 CHEN Ming ZANG Weiqi ZHOU Shan 《数学进展》 北大核心 2025年第6期1223-1232,共10页
A dominating induced matching(DIM)of G is an induced matching that dominates every edge of G.In this note,we completely determine the number of DIMs in the generalized Petersen graph P(n,k).We prove that if P(n,k)is a... A dominating induced matching(DIM)of G is an induced matching that dominates every edge of G.In this note,we completely determine the number of DIMs in the generalized Petersen graph P(n,k).We prove that if P(n,k)is a generalized Petersen graph with n=0(mod 5)and k=2,3(mod 5),then E(P(n,k))can be partitioned into five DIMs.Meanwhile,in the left cases k=0,1,4(mod 5),we build some counterexamples to show that there exist some P(n,k)'s which are DIM-free. 展开更多
关键词 dominating induced matching generalized Petersen graph
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MOCBOA:Multi-Objective Chef-Based Optimization Algorithm Using Hybrid Dominance Relations for Solving Engineering Design Problems
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作者 Nour Elhouda Chalabi Abdelouahab Attia +4 位作者 Abdulaziz S.Almazyad Ali Wagdy Mohamed Frank Werner Pradeep Jangir Mohammad Shokouhifar 《Computer Modeling in Engineering & Sciences》 2025年第4期967-1008,共42页
Multi-objective optimization is critical for problem-solving in engineering,economics,and AI.This study introduces the Multi-Objective Chef-Based Optimization Algorithm(MOCBOA),an upgraded version of the Chef-Based Op... Multi-objective optimization is critical for problem-solving in engineering,economics,and AI.This study introduces the Multi-Objective Chef-Based Optimization Algorithm(MOCBOA),an upgraded version of the Chef-Based Optimization Algorithm(CBOA)that addresses distinct objectives.Our approach is unique in systematically examining four dominance relations—Pareto,Epsilon,Cone-epsilon,and Strengthened dominance—to evaluate their influence on sustaining solution variety and driving convergence toward the Pareto front.Our comparison investigation,which was conducted on fifty test problems from the CEC 2021 benchmark and applied to areas such as chemical engineering,mechanical design,and power systems,reveals that the dominance approach used has a considerable impact on the key optimization measures such as the hypervolume metric.This paper provides a solid foundation for determining themost effective dominance approach and significant insights for both theoretical research and practical applications in multi-objective optimization. 展开更多
关键词 Multi-objective optimization chef-based optimization algorithm(CBOA) pareto dominance epsilon dominance cone-epsilon dominance strengthened dominance
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The Modern Paradox
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作者 Peter Takov 《Philosophy Study》 2025年第5期187-194,共8页
This paper is an attempt to explore the root of the modern paradox across multiple registers in order to uncover a persuasive pattern of contradiction that runs through the very fabric of contemporary existence.We dis... This paper is an attempt to explore the root of the modern paradox across multiple registers in order to uncover a persuasive pattern of contradiction that runs through the very fabric of contemporary existence.We discover that the very logic meant to emancipate the human subject-scientific mastery,bureaucratic order,economic growth,and many others,often recoil upon the subject,generating conditions of fragmentation,depersonalization,and spiritual aridity.Far from rejecting modernity wholesale,our task is a diagnostic one-to enter into the deep fabric of modernity and to decode its operating metaphors and interrogate what holds up the“scaffolding of collective life”.This is in a bid to find the rootedness of genuine human flourishing.Part of the answer,from our analysis,lies in a critical re-thinking within modernity without being subsumed by it. 展开更多
关键词 modernity FRAGMENTATION INDIVIDUALISM MANIPULATION CAPITALISM DOMINATION
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Preparation of Four Kinds of Fruit Enzymes and Detection of Their Antioxidant Activity
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作者 Hongbing QI Tianling ZHOU 《Asian Agricultural Research》 2025年第9期31-36,43,共7页
[Objectives]To prepare four kinds of fruit enzymes from pitaya(dragon fruit),papaya,orange and pineapple,and to detect their physicochemical properties and antioxidant activities.[Methods]Using pitaya,papaya,orange an... [Objectives]To prepare four kinds of fruit enzymes from pitaya(dragon fruit),papaya,orange and pineapple,and to detect their physicochemical properties and antioxidant activities.[Methods]Using pitaya,papaya,orange and pineapple as raw materials,pitaya enzyme,papaya enzyme,orange enzyme and pineapple enzyme were obtained by natural fermentation.The physical and chemical properties and antioxidant activity of the four fruit enzymes were analyzed,and the dominant strains in papaya ferment were identified.[Results]The pH of the four fruit enzymes ranged from 3.32 to 3.59.The sensory evaluation of orange and papaya enzymes was relatively superior;among them,the orange enzyme exhibited the highest hydroxyl radical scavenging rate(95.76%),while the pineapple enzyme had the highest total phenol content(27.21μg/mL).The papaya enzyme showed the highest values for DPPH,reducing power,and flavonoids,at 70.55,1.699,and 0.1216 mg/mL,respectively.Through the comprehensive comparing,the physicochemical properties and antioxidant activity of the papaya enzyme were relatively superior,with its dominant microbial species being Lactobacillus and Saccharomyces cerevisiae.[Conclusions]Papaya enzyme is a kind of functional food with great development potential,and this study can provide reference for the development of fruit enzyme with high added value. 展开更多
关键词 PAPAYA ENZYME Antioxidant activity Correlation DOMINANT strain
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Outer-Independent Roman Domination on Cartesian Product of Paths
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作者 Junzhe GUO Hong GAO Yuansheng YANG 《Journal of Mathematical Research with Applications》 2025年第1期11-19,共9页
Outer-independent Roman domination on graphs originates from the defensive strategy of Ancient Rome,which is that if any city without an army is attacked,a neighboring city with two armies could mobilize an army to su... Outer-independent Roman domination on graphs originates from the defensive strategy of Ancient Rome,which is that if any city without an army is attacked,a neighboring city with two armies could mobilize an army to support it and any two cities that have no army cannot be adjacent.The outer-independent Roman domination on graphs is an attractive topic in graph theory,and the definition is described as follows.Given a graph G=(V,E),a function f:V(G)→{0,1,2}is an outer-independent Roman dominating function(OIRDF)if f satisfies that every vertex v∈V with f(v)=0 has at least one adjacent vertex u∈N(v)with f(u)=2,where N(v)is the open neighborhood of v,and the set V0={v|f(v)=0}is an independent set.The weight of an OIRDF f is w(f)=∑_(v∈V)f(v).The value of minf w(f)is the outerindependent Roman domination number of G,denoted asγoiR(G).This paper is devoted to the study of the outer-independent Roman domination number of the Cartesian product of paths P_(n)□P_(m).With the help of computer,we find some recursive OIRDFs and then we present an upper bound ofγoiR(P_(n)□P_(m)).Furthermore,we prove the lower bound ofγoiR(P_(n)□P_(m))(n≤3)is equal to the upper bound.Hence,we achieve the exact value ofγoiR(P_(n)□P_(m))for n≤3 and the upper bound ofγoiR(P_(n)□P_(m))for n≥4. 展开更多
关键词 Roman domination outer-independent Roman domination Cartesian product graphs PATHS
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Perfect Double Roman Domination on Cographs
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作者 LI Peng XUE Xin-yi +1 位作者 LONG Yang-jing LI Xue-bo 《Chinese Quarterly Journal of Mathematics》 2025年第2期158-168,共11页
Consider a graph G=(V,E).A perfect double Roman dominating function(PDRDF for short)is a function h:V→{0,1,2,3}that satisfies the condition∑_(y∈NG[x],h(y)≥1)h(y)=|{y∈NG(x):h(y)≥1}|+2 for any x∈V with h(x)≤1.Th... Consider a graph G=(V,E).A perfect double Roman dominating function(PDRDF for short)is a function h:V→{0,1,2,3}that satisfies the condition∑_(y∈NG[x],h(y)≥1)h(y)=|{y∈NG(x):h(y)≥1}|+2 for any x∈V with h(x)≤1.The weightω(h)of this function is∑_(y∈V)h(y).The perfect double Roman domination number(PDRD-number)of G,denoted byγ_(dR)^(p)(G),is defined as the minimum weight among all PDRDFs of G.This article presents a comprehensive analysis of the PDRD-number of connected cographs,demonstrating that it falls within the set{2,3,4,5,6}.Furthermore,it establishes that for any integer i≥7,there is a connected cograph G such that its PDRD-number is equal to i. 展开更多
关键词 COGRAPHS Double Roman domination Perfect double Roman domination
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Molecular dissection of hemizygote-dependent dominance of super-early flowering in soybean
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作者 Xin Xu Yang Yu +15 位作者 Bingjun Jiang Dong Cao Lixin Zhang Hongchang Jia Xuegang Sun Li Chen Shan Yuan Fulu Chen Zefu Lu Yanhong Liu Mahmoud Naser Tingting Wu Cunxiang Wu Qingzhu Zhang Shi Sun Tianfu Han 《The Crop Journal》 2025年第3期828-839,共12页
In plants,numerous non-Mendelian inherited dominant effects,including over-,incomplete-,and codominance,are frequently observed,yet they remain insufficiently understood.A novel phenotype has been identified in specif... In plants,numerous non-Mendelian inherited dominant effects,including over-,incomplete-,and codominance,are frequently observed,yet they remain insufficiently understood.A novel phenotype has been identified in specific soybean transformants overexpressing a single 35S::GmFT2a copy:superearly flowering dominance is exclusively observed in hemizygotes,not in homozygotes.Homozygous individual exhibits si RNA-mediated DNA methylation,causing epigenetic transcriptional silencing,whereas no such effect occurs in hemizygotes.Intriguingly,two distinct rounds of DNA methylation establishment occur,each mediated by a different mechanism.The homozygotes that derived from the hemizygous mother plants carrying 35S::GmFT2a locus was associated with the initiation of CHHcontext DNA methylation at 35S promoters mediated by 21 and 22 nucleotide(nt)si RNAs.Subsequently,24 nt si RNAs contribute to additional CHG-and CG-context DNA methylation at 35S promoters during the homozygosity of genes in plants already homozygous in maternal lineage.Reducing DNA methylation levels can be achieved by generating a hemizygous genotype through a crossing experiment with a recessive genotype.This research has unveiled a phenomenon:hemizygote-dependent dominance resulting from transcriptional silencing in homozygote offsprings.It provides new insights into the molecular mechanism underlying dominant effects. 展开更多
关键词 SOYBEAN Hemizygote-dependent dominance Flowering time SIRNA DNA methylation
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Regulatory signatures involved in the cell cycle pathway contribute to egg production heterosis in chicken
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作者 Jingwei Yuan Yuanmei Wang +8 位作者 Yanyan Sun Yunlei Li Aixin Ni Qin Li Hanhan Yang Xinying Xu Yunhe Zong Hui Ma Jilan Chen 《Journal of Animal Science and Biotechnology》 2025年第2期551-564,共14页
Background Crossbreeding is widely promoted as an efficient strategy to improve the productivity in agriculture.The molecular mechanism underlying heterosis for egg production is always intriguing in chicken.The trans... Background Crossbreeding is widely promoted as an efficient strategy to improve the productivity in agriculture.The molecular mechanism underlying heterosis for egg production is always intriguing in chicken.The transcriptional dynamic changes play a crucial role in the formation of heterosis,but little is known for the egg production traits.Results In present study,we measured the continuous manifestation of heterosis ranging from 2.67%to 10.24%for egg number in the crossbreds generated by reciprocal crossing White Leghorn and Beijing You chicken.The high-quality transcriptomes of ovary for purebreds(WW and YY)and crossbreds(WY and YW)in 5 laying stages were sequenced and integrated to identify regulatory networks relevant to the heterosis.We found highly conserved transcriptional features among 4 genetic groups.By using weighted gene co-expression network analysis(WGCNA),we obtained multiple gene co-expression modules that were significantly correlated with egg number for each group.The common KEGG pathways including apelin signaling pathway,cell cycle,ribosome,spliceosome and oxidative phosphorylation,were screened for the 2 crossbreds.Then,we identified consensus co-expression modules(CMs)that showed divergent expression pattern among crossbred(WY or YW)and purebreds(WW and YY).The hub genes of CMs were again overrepresented in the cell cycle pathway,and the crossbreds exhibited temporally complementary dominance of hub genes in the 5 laying stages.These results suggested that the crossbreds inherited from both parents to maintain the ovary function by cell cycle-related genes,contributing to the persistent heterosis for egg production.Furthermore,the dominant genes including MAD2L1,CHEK2 and E2F1 were demonstrated to function in ovarian follicle development and maturation and could be the candidate genes for egg production heterosis.Conclusion Our study characterized the dynamic profile of genome-wide gene expression in ovary and highlighted the role of dominant expression of cell cycle pathway genes in heterosis.These findings provided new insights for the molecular mechanism of egg production heterosis,which would facilitate the rational choice of suitable parents for producing crossbred chickens with higher egg production. 展开更多
关键词 Cell cycle CHICKEN DOMINANCE Egg production heterosis Ovary transcriptome WGCNA
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Corrigendum to“Crown saturation and intrasexual dominance:Evidence of a negatively correlated handicap in male Saffron Finches”[Avian Res.16(2025)100241]
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作者 Camilo Ernesto Espinosa James Montoya Lerma +1 位作者 Hector Fabio Rivera-Gutierrez Lorena Cruz-Bernate 《Avian Research》 2025年第2期301-301,共1页
The authors regret that the declaration of Acknowledgement as below is missing in the paper:AcknowledgementWe are grateful to the Department of Biology and Postgraduate Sciences-Biology of the Universidad del Valle,Ca... The authors regret that the declaration of Acknowledgement as below is missing in the paper:AcknowledgementWe are grateful to the Department of Biology and Postgraduate Sciences-Biology of the Universidad del Valle,Cali-Colombia for their support of the project;to Wilmar Torres MSc.for his statistical advice;to the biologist Helen Burnham MSc.for the translation of the document;to Isabel Castro and all the members of the Ornithology and Animal Behaviour Laboratory-OYCA of Universidad del Valle for their invaluable support in the field.We sincerely thank the anonymous re-viewers for their invaluable feedback and contributions to our manuscript. 展开更多
关键词 intrasexual dominance HANDICAP declaration acknowledgement crown saturation saffron finches ACKNOWLEDGEMENT
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Distribution Characteristics and Genetic Mechanisms of Geothermal Radon Mineral Water in Shandong Province
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作者 HU Caiping BAI Xinfei +10 位作者 ZHU Lixin SONG Jinyu PENG Wenquan YANG Shijiao HONG Huanren ZHAO Tong ZHANG Jun YU Chao WANG Tao SONG Liang DONG Na 《Acta Geologica Sinica(English Edition)》 2025年第4期1169-1181,共13页
This study systematically investigates the concentration of ^(222)Rn in geothermal fluids and the distribution of geothermal radon mineral water in Shandong Province,with the aim of elucidating formation mechanisms an... This study systematically investigates the concentration of ^(222)Rn in geothermal fluids and the distribution of geothermal radon mineral water in Shandong Province,with the aim of elucidating formation mechanisms and influencing factors.The findings indicate that the overall abundance of ^(222)Rn in geothermal fluids across the region is relatively low.Geothermal radon mineral water is primarily located within banded thermal reservoirs associated with bedrock fracture structures in the Ludong and Luxi uplift geothermal zones.The study reveals that the ionic composition,radioactivity intensity,and extent of water-rock interactions exert only effects in the concentration of ^(222)Rn in geothermal fluids.The formation of geothermal radon mineral water is predominantly governed by“fracture-controlled”mechanisms,with thermal reservoir lithology,fracture tectonics,and seismic activity serving as key determinants.Additionally,the enrichment of ^(222)Rn in geothermal fluids is influenced by factors such as geothermal fluid temperature,depth of occurrence,cap rock thickness,and alteration processes.The genetic mechanisms of geothermal radon mineral water can be categorized into two types:„native‟and„composite‟.These findings provide critical insights into the exploration and development of geothermal radon mineral water resources in Shandong and similar regions. 展开更多
关键词 geothermal radon mineral water fracture-controlled dominant factors genetic mechanisms NATIVE composite
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Dominant Modes of Spring Drought Variability in Southern China During 1979-2022 and the Associated Drivers
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作者 ZHOU Jia-yu QIU Wen-tian +2 位作者 ZHAO Qing-hong CHEN Xi DENG Kai-qiang 《Journal of Tropical Meteorology》 2025年第4期331-340,共10页
Utilizing the Standardized Precipitation Evapotranspiration Index(SPEI)and ERA5 reanalysis data,this study investigates the variability of spring drought in southern China from 1979 to 2022 and its associated drivers.... Utilizing the Standardized Precipitation Evapotranspiration Index(SPEI)and ERA5 reanalysis data,this study investigates the variability of spring drought in southern China from 1979 to 2022 and its associated drivers.The results indicate that southern China experienced interdecadal changes in SPEI over the past several decades,which can be concluded that drought severity intensified from 1979 to 2010,whereas a transition shift towards increased wetness occurred from 2010 to 2022.The first Empirical Orthogonal Function(EOF1)mode of SPEI variability in southern China accounts for 44.37%of the total variance,reflecting a uniform variation of SPEI across the region.In contrast,the second Empirical Orthogonal Function(EOF2),which explains 24.41%of the total variance,reveals a west-east dipole pattern in SPEI variability.Further analysis indicates that the positive phase of EOF1 is primarily driven by warm sea surface temperature anomalies(SSTAs)in the tropical eastern Pacific.These anomalies induce an anomalous anticyclone over the Philippine Sea,enhancing water vapor transport to southern China during spring.The positive phase of EOF2 is jointly influenced by warm SSTAs in the tropical Indian Ocean and the central Pacific;the latter induces anticyclonic anomalies over the Philippine Sea,which enhance water vapor transport from the western Pacific and increase precipitation in the eastern part of southern China.However,the warm SSTAs in the tropical Indian Ocean trigger an anomalous anticyclone over South Asia,inhibiting water vapor transport from the Bay of Bengal to the western part of southern China and thus reducing precipitation there. 展开更多
关键词 drought variability dominant modes southern China SPRING
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Hereditary alpha tryptasemia and clinical implications
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作者 Ece Tüsüz Önata Öner Özdemir Süreyya Savaşan 《World Journal of Clinical Cases》 2025年第21期6-15,共10页
Hereditary alpha tryptasemia was first described in 2016 and is the most common(up to 72%)cause of elevated serum basal tryptase(TPS).The clinical presentation of this condition,which is caused by copy number gains in... Hereditary alpha tryptasemia was first described in 2016 and is the most common(up to 72%)cause of elevated serum basal tryptase(TPS).The clinical presentation of this condition,which is caused by copy number gains in the TPSAB1 gene encoding serumαTPS,is variable for each patient.Some patients are asymptomatic,whereas in others,especially those with increased mast cell activation,it has been associated with a higher risk of anaphylaxis.Better characterization of this entity is important to identify atrisk patients and to develop new treatment strategies.This review provided an overview of hereditary alpha tryptasemia and increased awareness of this condition by discussing the current information in the literature. 展开更多
关键词 Tryptasemia Autosomal dominant Hereditary alpha tryptasemia Mast cell Tyrosine kinase protein
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Assessment of plant diversity in the Surkhan-Sherabad Region,Uzbekistan by grid mapping
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作者 Inom JURAMURODOV Rustam URALOV +6 位作者 Dilmurod MAKHMUDJANOV LU Chunfang Feruz AKBAROV Sardor PULATOV Bakhtiyor KARIMOV Orzimat TURGINOV Komiljon TOJIBAEV 《Journal of Arid Land》 2025年第3期394-410,共17页
In floristic research,the grid mapping method is a crucial and highly effective tool for investigating the flora of specific regions.This methodology aids in the collection of comprehensive data,thereby promoting a th... In floristic research,the grid mapping method is a crucial and highly effective tool for investigating the flora of specific regions.This methodology aids in the collection of comprehensive data,thereby promoting a thorough understanding of regional plant diversity.This paper presents findings from a grid mapping study conducted in the Surkhan-Sherabad botanical-geographic region(SShBGR),acknowledged as one of the major floristic areas in southwestern Uzbekistan.Using an expansive dataset of 14,317 records comprised of herbarium specimens and field diary entries collected from 1897 to 2023,we evaluated the stages and seasonal dynamics of data accumulation,species richness(SR),and collection density(CD)within 5 km×5 km grid cells.We further examined the taxonomic and life form composition of the region's flora.Our analysis revealed that the grid mapping phase(2021–2023)produced a significantly greater volume of specimens and taxonomic diversity compared with other periods(1897–1940,1941–1993,and 1994–2020).Field research spanned 206 grid cells during 2021–2023,resulting in 11,883 samples,including 6469 herbarium specimens and 5414 field records.Overall,fieldwork covered 251 of the 253 grid cells within the SShBGR.Notably,the highest species diversity was documented in the B198 grid cell,recording 160 species.In terms of collection density,the E198 grid cell produced 475 samples.Overall,we identified 1053 species distributed across 439 genera and 78 families in the SShBGR.The flora of this region aligned significantly with the dominant families commonly found in the Holarctic,highlighting vital ecological connections.Among our findings,the Asteraceae family was the most polymorphic,with 147 species,followed by the continually stable and diverse Poaceae,Fabaceae,Brassicaceae,and Amaranthaceae.Besides,our analysis revealed a predominance of therophyte life forms,which constituted 52%(552 species)of the total flora.The findings underscore the necessity for continual data collection efforts to further enhance our understanding of the biodiversity in the SShBGR.The results of this study demonstrated that the application of grid-based mapping in floristic studies proves to be an effective tool for assessing biodiversity and identifying key taxonomic groups. 展开更多
关键词 grid mapping species richness collection density TAXONOMY dominant species life form therophyte Central Asia
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A Novel Selenite-Reducing Bacterium Bacillus pseudomycoides SA14 Isolated from Se-Enriched Soil and Its Potential Se Biofortification on Brassica chinensis L.
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作者 Xianxin Huang Yanhong Wang +5 位作者 Helin Wang Xinyan Shi Chunlei Huang Hanqin Yin Yixian Shao Ping Li 《Journal of Earth Science》 2025年第4期1756-1765,共10页
Microbial participation in biofortification can improve the availability of selenium(Se)in soil and contribute to the enrichment of Se in crops.In this study,a selenite(Se(IV))reducing strain was isolated from Se-rich... Microbial participation in biofortification can improve the availability of selenium(Se)in soil and contribute to the enrichment of Se in crops.In this study,a selenite(Se(IV))reducing strain was isolated from Se-rich soil,and its Se transformation and bio-enhancement ability were studied.The strain was identified as Bacillus pseudomycoides and could reduce more than 93.48%of 1.0 m M Se(IV)in 54 h.The results of scanning electron microscope(SEM)and energy dispersive Xray spectrometry(EDS)showed that Se(IV)was reduced to Se(0),and Se nanoparticles(Se NPs)were eventually formed.In pot experiments,B.pseudomycoides SA14 could promote the bioavailable Se in soils and the concentration of Se in Brassica chinensis L..The concentrations of watersoluble Se,ion exchange Se and carbonate-binding Se in soil were increased by 23.13%,22.05%and 30.89%,respectively.The Se concentration of Brassica chinensis L.in pot experiments was increased by 145.05%.The relative abundance of Bacillus in soil increased from 0.97%to 2.08%in the pot experiments.As far as we know,this is the first report of Se reduction by B.pseudomycoides.This study might provide a prospective strategy for microbial fortification of Se in crops. 展开更多
关键词 Se(IV)reduction Bacillus pseudomycoides BIOAVAILABILITY BIOFORTIFICATION dominant community natural environment
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The Inheritance, Pathophysiology, and Treatment for Polycystic Kidney Disease and Its Effects on the Heart—A Literature Review
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作者 Harika Paruchuri Kelley Williams Terry Oroszi 《International Journal of Clinical Medicine》 2025年第1期95-111,共17页
Polycystic kidney disease (PKD) is an autosomal dominant genetic disorder that causes the formation of multiple cysts in the kidneys, leading to kidney failure. PKD is a common condition affecting approximately 1 in 5... Polycystic kidney disease (PKD) is an autosomal dominant genetic disorder that causes the formation of multiple cysts in the kidneys, leading to kidney failure. PKD is a common condition affecting approximately 1 in 500 individuals worldwide. The most prevalent type of PKD is autosomal dominant PKD (ADPKD). ADPKD is caused by mutations in either the PKD1 or PKD2 genes, which encode for proteins involved in cell growth and differentiation. These mutations lead to the formation of fluid-filled cysts in the kidneys, which can eventually lead to kidney failure. In addition to affecting the kidneys, PKD can also cause cysts in other organs, such as the liver, pancreas, and spleen. PKD can also lead to various complications, including high blood pressure, heart valve abnormalities, and brain aneurysms. This review focuses on the inheritance, pathophysiology, and treatment of PKD, with a specific emphasis on its effects on the cardiovascular system. Currently, there is no cure for PKD. However, several treatments are available to manage the symptoms and complications of the disease. These treatments include medications to control blood pressure, pain relievers, antibiotics for infections, and dialysis or kidney transplantation for kidney failure. Tolvaptan is the only FDA-approved drug specifically for ADPKD and has been shown to slow disease progression. In addition to summarizing current treatment options, this review will discuss promising future treatments, such as gene therapy and stem cell therapy. 展开更多
关键词 Polycystic Kidney Disease Autosomal Dominant Autosomal Recessive End-Stage Renal Disease EPIDEMIOLOGY PATHOPHYSIOLOGY Cardiovascular Diseases
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Temporal stability responses to nitrogen addition in Tibetan alpine grasslands:A community composition perspective
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作者 Ning Zong Peili Shi 《Journal of Integrative Agriculture》 2025年第3期871-884,共14页
Plant community composition typically undergoes progressive changes along environmental gradients.However,most experimental studies have focused on individual communities,so it remains unclear how exogenous nutrient i... Plant community composition typically undergoes progressive changes along environmental gradients.However,most experimental studies have focused on individual communities,so it remains unclear how exogenous nutrient inputs affect the stability of plant communities along environmental gradients.Along a rainfall gradient on the northern Tibetan Plateau,we conducted an 8-year nitrogen(N)addition experiment in four alpine grasslands:alpine desert steppe(ADS),alpine steppe(AS),alpine meadow steppe(AMS),alpine meadow(AM),and we used twoway ANOVA to examine the effects of N addition on the temporal stability of these different alpine grasslands.We found that community aboveground biomass showed saturation trends in AM and AMS with increasing N gradients,while there was no change in AS and a gradual increase in ADS.The temporal stability showed different patterns of gradual decreases in ADS and AM,and a unimodal trend in AMS with increasing N gradients.However,N addition had no effect on the temporal stability of AS.Dominant species stability was the controlling factor for alpine grasslands along the transect,while the effect of asynchrony gradually increased with decreasing precipitation.These findings highlight that community composition,especially the dominant species,along the environmental gradient can mediate the effects of N inputs on community temporal stability.Thus,the conservation and restoration of the dominant species are particularly important under future scenarios of increased atmospheric N deposition. 展开更多
关键词 community composition dominant species environmental gradient plant abundance group Tibetan Plateau
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Response of temporal stability of plant community biomass in alpine meadows of the Qinghai-Xizang Plateau,China to climate warming and nitrogen deposition
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作者 XIANG Xuemei DE Kejia +4 位作者 ZHANG Lin LIN Weishan FENG Tingxu LI Fei WEI Xijie 《Journal of Arid Land》 2025年第10期1425-1442,共18页
In recent years,many studies have focused on the effects of global climate warming and increased nitrogen deposition on the structure and function of grassland ecosystem.However,there are still significant uncertainti... In recent years,many studies have focused on the effects of global climate warming and increased nitrogen deposition on the structure and function of grassland ecosystem.However,there are still significant uncertainties in the response mechanism of stability of plant community biomass in alpine meadows of the Qinghai-Xizang Plateau,China to these two major climate factors.Given this,based on field control experiments,this study systematically evaluated the effects of different levels of climate warming(W0(no warming),W1(air temperature increased by 0.47℃ or soil temperature increased by 0.61℃),W2(air temperature increased by 0.92℃ or soil temperature increased by 1.09℃),W3(air temperature increased by 1.44℃ or soil temperature increased by 1.95℃)),nitrogen deposition(N0(0 kg N/(hm^(2)·a)),N16(16 kg N/(hm^(2)·a)),and N32(32 kg N/(hm^(2)·a))),and their interactions on plant community biomass and its temporal stability,and explored its potential regulatory mechanisms.The results showed that the biomass of total community,Gramineae,and dominant species increased significantly with increasing temperature,but the biomass of common and rare species decreased significantly.Nitrogen deposition also significantly promoted the biomass accumulation of community and gramineous plants.Under the treatment of W3N32,the biomass of plant community,Gramineae,and dominant species reached the highest values,indicating that there was a synergistic effect under this treatment.Structural equation model showed that increasing temperature significantly decreased the stability of plant community biomass by reducing the stability of grass and dominant species biomass and weakening species asynchronism.Interaction of increased nitrogen deposition and temperature increased the biomass fluctuation of grass functional group,thus amplifying its negative influence on community stability.More attention should be paid to the response and regulatory mechanisms of dominant species and functional groups under global climate change.This study provides a theoretical basis for revealing the stability maintenance mechanism of alpine grassland and also provides scientific support for the development of future grassland ecosystem management and assessment. 展开更多
关键词 alpine meadows climate change plant community biomass dominant species species asynchrony
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Canopy structural heterogeneity drives α and β species-genetic diversity correlations in a Chinese subtropical forest
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作者 Zhiliang Yao Xia Pan +6 位作者 Xin Yang Xiaona Shao Bin Wang Yun Deng Zhiming Zhang Qiaoming Li Luxiang Lin 《Plant Diversity》 2025年第1期106-114,共9页
Patterns and drivers of species–genetic diversity correlations(SGDCs)have been broadly examined across taxa and ecosystems and greatly deepen our understanding of how biodiversity is maintained.However,few studies ha... Patterns and drivers of species–genetic diversity correlations(SGDCs)have been broadly examined across taxa and ecosystems and greatly deepen our understanding of how biodiversity is maintained.However,few studies have examined the role of canopy structural heterogeneity,which is a defining feature of forests,in shaping SGDCs.Here,we determine what factors contribute toα-andβ-species–genetic diversity correlations(i.e.,α-andβ-SGDCs)in a Chinese subtropical forest.For this purpose,we used neutral molecular markers to assess genetic variation in almost all adult individuals of the dominant tree species,Lithocarpus xylocarpus,across plots in the Ailaoshan National Natural Reserve.We also quantified microhabitat variation by quantifying canopy structure heterogeneity with airborne laser scanning on 201-ha subtropical forest plots.We found that speciesα-diversity was negatively correlated with geneticα-diversity.Canopy structural heterogeneity was positively correlated with speciesα-diversity but negatively correlated with geneticα-diversity.These contrasting effects contributed to the formation of a negativeα-SGDC.Further,we found that canopy structural heterogeneity increases speciesα-diversity and decreases geneticα-diversity by reducing the population size of target species.Speciesβ-diversity,in contrast,was positively correlated with geneticβ-diversity.Differences in canopy structural heterogeneity between plots had non-linear parallel effects on the two levels ofβ-diversity,while geographic distance had a relatively weak effect onβ-SGDC.Our study indicates that canopy structural heterogeneity simultaneously affects plot-level community species diversity and population genetic diversity,and species and genetic turnover across plots,thus drivingα-andβ-SGDCs. 展开更多
关键词 Dominant species Forest structure LIDAR Lithocarpus xylocarpus Speciesegenetic diversity correlation Subtropical evergreen broad-leaved forest
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Control of volcanic lithofacies on play fairways:A case study of the Huoshiling Formation in the Dehui faulted depression,southern Songliao Basin,China
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作者 Jijun Li Chenghong Luo +8 位作者 Tianhong Yang Tongyao Zhang Peng Hao Bo Wang Yan Cheng Libin Song Kexin Jia Lili Li Chao Liu 《Energy Geoscience》 2025年第2期155-173,共19页
Volcanic reservoirs demonstrate strong heterogeneity and substantial variations in productivity due to the complexity of volcanic eruption and lithology.The main types of reservoir space are not clear,and the dominant... Volcanic reservoirs demonstrate strong heterogeneity and substantial variations in productivity due to the complexity of volcanic eruption and lithology.The main types of reservoir space are not clear,and the dominant lithofacies distribution,particularly the favorable areas for high-quality reservoirs,remains to be determined.In this paper,the Huoshiling Formation in the Dehui faulted depression,Songliao Basin is taken as an example to carry out the multi-scale joint characterization of its pore throat structure,establish a reservoir evaluation standard that considers both the gas content and seepage capacity,and perform reservoir evaluation and play fairway mapping under facies control.The results show that the storage space types of the gas-bearing reservoirs in the faulted depression can be ascribed into three categories and six subcategories according to the pore throat and pore characteristics.In terms of pore sizes,volcaniclastic lava rank the first,followed by volcaniclastic rocks,sedimentary volcaniclastic rocks and volcanic lava.The comprehensive evaluation parameter(Φ·K·Sg,whereΦis porosity,K permeability,and Sggas saturation)of high-quality reservoirs are all greater than 0.1.The volcanic reservoirs in the Stage-III strata are the highest in quality and largest in area of play fairways.The thermal debris flow sub-facies developed at Stage III are mainly seen along the western strike-slip fault zone in the Debei sub-sag and the southwest Nong'an tectonic belt,while those developed at Stage I are distributed along the central and eastern fault zones in the southeastern Baojia sub-sag.The favorable layer evaluation and favorable area delineation under facies control will be of certain reference significance for subsequent exploration and development of volcanic gas reservoirs. 展开更多
关键词 Dehui faulted depression Volcanic rock Pore throat characteristics Reservoir evaluation Dominant lithofacies Play fairway
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