Objectives This study aimed to explore the research trends,thematic structures,and core competency domains in the field of nursing-related digital and artificial intelligence(AI)technologies.Methods A bibliometric ana...Objectives This study aimed to explore the research trends,thematic structures,and core competency domains in the field of nursing-related digital and artificial intelligence(AI)technologies.Methods A bibliometric analysis was conducted in accordance with the PRISMA 2020 statement.Peer-reviewed articles published in English from 2015 to 2025 were retrieved from Scopus,Web of Science,and PubMed.Thematic clustering was conducted using the Louvain algorithm and cosine similarity.A subset of 66 frequently cited articles was then qualitatively synthesized to capture core competencies across clusters.Results A total of 83,807 articles were included for bibliometric analysis.Of these,66 articles were chosen for thematic analysis.Five major thematic clusters were identified:remote care in primary settings,oncology and palliative care,nurse education and training,safety and quality in nursing practice,and geriatric and dementia care.Additionally,four competency domains were identified:telehealth and remote communication,health systems and informatics,digital tools in practice,and AI-powered decision support.A clear shift in research focus was observed,with the emphasis transitioning from foundational digital skills before the COVID-19 pandemic to more advanced competencies during the post-pandemic digital transformation,encompassing ethical reasoning,immersive technology use,and AI integration.Conclusions Integrating digital and AI technologies is reshaping nursing practice across various thematic areas and competency domains,highlighting a transition from foundational digital tasks to AI-supported decision-making and ethically informed technology use.This study provides a structured overview of evolving competencies in digital nursing and synthesizes evidence to support future research,curriculum design,and policy planning.展开更多
Domain Generation Algorithms(DGAs)continue to pose a significant threat inmodernmalware infrastructures by enabling resilient and evasive communication with Command and Control(C&C)servers.Traditional detection me...Domain Generation Algorithms(DGAs)continue to pose a significant threat inmodernmalware infrastructures by enabling resilient and evasive communication with Command and Control(C&C)servers.Traditional detection methods-rooted in statistical heuristics,feature engineering,and shallow machine learning-struggle to adapt to the increasing sophistication,linguistic mimicry,and adversarial variability of DGA variants.The emergence of Large Language Models(LLMs)marks a transformative shift in this landscape.Leveraging deep contextual understanding,semantic generalization,and few-shot learning capabilities,LLMs such as BERT,GPT,and T5 have shown promising results in detecting both character-based and dictionary-based DGAs,including previously unseen(zeroday)variants.This paper provides a comprehensive and critical review of LLM-driven DGA detection,introducing a structured taxonomy of LLM architectures,evaluating the linguistic and behavioral properties of benchmark datasets,and comparing recent detection frameworks across accuracy,latency,robustness,and multilingual performance.We also highlight key limitations,including challenges in adversarial resilience,model interpretability,deployment scalability,and privacy risks.To address these gaps,we present a forward-looking research roadmap encompassing adversarial training,model compression,cross-lingual benchmarking,and real-time integration with SIEM/SOAR platforms.This survey aims to serve as a foundational resource for advancing the development of scalable,explainable,and operationally viable LLM-based DGA detection systems.展开更多
In this study,the wave motion in elastodynamics for unbounded media is modeled using an unsplit-field perfectly matched layer(PML)formulation that is solved by employing an isogeometric analysis(IGA).In the adopted co...In this study,the wave motion in elastodynamics for unbounded media is modeled using an unsplit-field perfectly matched layer(PML)formulation that is solved by employing an isogeometric analysis(IGA).In the adopted combination,the non-uniform rational B-spline(NURBS)functions are employed as basis functions.Moreover,the unbounded and artificial domains,defined in the PML method,are contained in a single patch domain.Based on the proposed scheme,the approximation of the geometry problem is set in a new scheme in which the PML’s absorbing and attenuation properties and the description of traveling waves can be represented.This includes a higher continuity and smoother approximation of the computed domain.As high-order NURBS basis functions are non-interpolatory,a penalty method is present to apply a time-dependent displacement load.The performance of the NURBS-based PML is analyzed through numerical examples for 1D and 2D domains,considering homogeneous and heterogeneous media.Further,we verify the long-time numerical stability of the present method.The developed method can be used to simulate hypothetical stratified domains commonly encountered in soil-structure interaction analyses.展开更多
In this paper,we study the weighted higher order semilinear equation in an exterior domain(-△)^(m)u=|x|^(α)g(u)in R^(N)\B_(R_(0)),where N≥1,m≥2 are integers,α>-2m,g is a continuous and nondecreasing function i...In this paper,we study the weighted higher order semilinear equation in an exterior domain(-△)^(m)u=|x|^(α)g(u)in R^(N)\B_(R_(0)),where N≥1,m≥2 are integers,α>-2m,g is a continuous and nondecreasing function in(0,+∞)and positive in(0,+∞),B_(R_(0))is the ball of the radius R0 centered at the origin.We prove that a positive supersolution of the problem which verifies(-△)_(i)u>0 in R^(N)\B_(R_(0))(i=0,…,m-1)exists if and only if N>2m and∫_(0)^(δ)g(t)/t^(2(N-m)+α/N-2m)dt<∞,,for someδ>0.We further obtain some existence and nonexistence results for the positive solution to the Dirichlet problem when g(u)=u^(p)with p>1,by using the Pohozaev identity and an embedding lemma of radial Sobolev spaces.展开更多
Natural biomass-derived carbon material is one promising alternative to traditional graphene-based catalyst for oxygen electrocatalysis.However,their electrocatalytic performance were constrained by the limited modula...Natural biomass-derived carbon material is one promising alternative to traditional graphene-based catalyst for oxygen electrocatalysis.However,their electrocatalytic performance were constrained by the limited modulating strategy.Herein,using N-doped commercial coconut shell-derived activated carbon(AC)as catalyst model,the controllably enhanced sp^(2)-C domains,through an flash Joule heating process,effectively improve the edge defect density and overall graphitization degree of AC catalyst,which tunes the electronic structure of N configurations and accelerates electron transfer,leading to excellent oxygen reduction reaction performance(half-wave potential of 0.884 VRHE,equivalent to commercial 20%Pt/C,with a higher kinetic current density of 5.88 mA cm^(−2))and oxygen evolution reaction activity(overpotential of 295 mV at 10 mA cm^(2)).In a Zn-air battery,the catalyst shows outstanding cycle stability(over 1200 h)and a peak power density of 121 mW cm^(−2),surpassing commercial Pt/C and RuO_(2)catalysts.Density functional theory simulation reveals that the enhanced catalytic activity arises from the axial regulation of local sp^(2)-C domains.This work establishes a robust strategy for sp^(2)-C domain modulation,offering broad applicability in natural biomass-based carbon catalysts for electrocatalysis.展开更多
Soft robots, inspired by the flexibility and versatility of biological organisms, have potential in a variety of applications. Recent advancements in magneto-soft robots have demonstrated their abilities to achieve pr...Soft robots, inspired by the flexibility and versatility of biological organisms, have potential in a variety of applications. Recent advancements in magneto-soft robots have demonstrated their abilities to achieve precise remote control through magnetic fields, enabling multi-modal locomotion and complex manipulation tasks. Nonetheless, two main hurdles must be overcome to advance the field: developing a multi-component substrate with embedded magnetic particles to ensure the requisite flexibility and responsiveness, and devising a cost-effective,straightforward method to program three-dimensional distributed magnetic domains without complex processing and expensive machinery. Here, we introduce a cost-effective and simple heat-assisted in-situ integrated molding fabrication method for creating magnetically driven soft robots with three-dimensional programmable magnetic domains. By synthesizing a composite material with neodymium-iron-boron(NdFeB) particles embedded in a polydimethylsiloxane(PDMS) and Ecoflex matrix(PDMS:Ecoflex = 1:2 mass ratio, 50% magnetic particle concentration), we achieved an optimized balance of flexibility, strength, and magnetic responsiveness. The proposed heat-assisted in-situ magnetic domains programming technique,performed at an experimentally optimized temperature of 120℃, resulted in a 2 times magnetization strength(9.5 mT) compared to that at 20℃(4.8 m T), reaching a saturation level comparable to a commercial magnetizer. We demonstrated the versatility of our approach through the fabrication of six kinds of robots, including two kinds of two-dimensional patterned soft robots(2D-PSR), a circular six-pole domain distribution magnetic robot(2D-CSPDMR), a quadrupedal walking magnetic soft robot(QWMSR), an object manipulation robot(OMR), and a hollow thin-walled spherical magneto-soft robot(HTWSMSR). The proposed method provides a practical solution to create highly responsive and adaptable magneto-soft robots.展开更多
In this paper,the Paley-Wiener theorem is extended to the analytic function spaces with general weights.We first generalize the theorem to weighted Hardy spaces Hp(0<p<∞)on tube domains by constructing a sequen...In this paper,the Paley-Wiener theorem is extended to the analytic function spaces with general weights.We first generalize the theorem to weighted Hardy spaces Hp(0<p<∞)on tube domains by constructing a sequence of L^(1)functions converging to the given function and verifying their representation in the form of Fourier transform to establish the desired result of the given function.Applying this main result,we further generalize the Paley-Wiener theorem for band-limited functions to the analytic function spaces L^(p)(0<p<∞)with general weights.展开更多
In this paper,we give a complete characterization of all self-adjoint domains of odd order differential operators on two intervals.These two intervals with all four endpoints are singular(one endpoint of each interval...In this paper,we give a complete characterization of all self-adjoint domains of odd order differential operators on two intervals.These two intervals with all four endpoints are singular(one endpoint of each interval is singular or all four endpoints are regulars are the special cases).And these extensions yield"new"self-adjoint operators,which involve interactions between the two intervals.展开更多
In this paper,we extend the definition of almost starlike mappings of order 1/2 on B n to the almost starlike mappings of order α on the bounded starlike circular domains in C n,and give the growth theorem of it....In this paper,we extend the definition of almost starlike mappings of order 1/2 on B n to the almost starlike mappings of order α on the bounded starlike circular domains in C n,and give the growth theorem of it. This type of domain on which we discuss is rather general,in the sense that the domain must be starlike if there exists a normalized biholomorphic starlike mapping on it.展开更多
The partitioning of membrane proteins into lipid domains in cellular membranes is closely associated with the realization of the protein functions and it is influenced by various factors such as the post-translational...The partitioning of membrane proteins into lipid domains in cellular membranes is closely associated with the realization of the protein functions and it is influenced by various factors such as the post-translational modification of palmitoylation.However,the molecular mechanism of the effect of palmitoylation on membrane protein partitioning into the lipid domains remains elusive.In this work,taking human peripheral myelin protein 22(PMP22)as an example,we employ coarse-grained molecular dynamics simulations to investigate the partitioning of both the natural PMP22 and the palmitoylated PMP22(pal-PMP22)into the lipid domains of model myelin membranes.The results indicate that palmitoylation drives PMP22 to localize at the boundary of the liquid-ordered(Lo)and liquid-disordered(Ld)domains and increases the possibility of PMP22 partitioning into the Lo domains by changing the hydrophobic length of the proteins and perturbing the ordered packing of tails of the saturated lipids in the Lo domains.This work offers some novel insights into the role of palmitoylation in modulating the function of membrane proteins in cellular membranes.展开更多
The authors obtain the growth and covering theorems for strongly starlike mappings of order α on bounded starlike circular domains.This kind of domain discussed is rather general,since the domain must be starlike if ...The authors obtain the growth and covering theorems for strongly starlike mappings of order α on bounded starlike circular domains.This kind of domain discussed is rather general,since the domain must be starlike if exists a normalized biholomorphic starlike mapping on it.展开更多
In this paper, we give a property of normalized biholomorphic convex mappings on the first, second and third classical domains: for any Z0 belongs to the classical domains,f maps each neighbourhood with the center Z0,...In this paper, we give a property of normalized biholomorphic convex mappings on the first, second and third classical domains: for any Z0 belongs to the classical domains,f maps each neighbourhood with the center Z0, which is contained in the classical domains,to a convex domain.展开更多
In many metazoan species, germ cell formation requires the germ plasm, a specialized cytoplasm which often con-tains electron dense structures. Genes required for germ cell formation in Drosophila have been isolated p...In many metazoan species, germ cell formation requires the germ plasm, a specialized cytoplasm which often con-tains electron dense structures. Genes required for germ cell formation in Drosophila have been isolated predominantlyin screens for maternal-effect mutations. One such gene is tudor (tud); without proper tud function germ cell formationdoes not occur. Unlike other genes involved in Drosophila germ cell specification tud is dispensable for other somaticfunctions such as abdominal patterning. It is not known how TUD contributes at a molecular level to germ cell forma-tion but in tud mutants, polar granule formation is severely compromised, and mitochondrially encoded ribosomal RNAsdo not localize to the polar granule. TUD is composed of 11 repeats of the protein motif called the Tudor domain. Thereare similar proteins to TUD in the germ line of other metazoan species including mice. Probable vertebrate orthologuesof Drosophila genes involved in germ cell specification will be discussed.展开更多
In this paper, Schwarz-Pick estimates for high order Fr′echet derivatives of bounded holomorphic functions on three kinds of classical domains are presented. We generalize the early work on Schwarz-Pick estimates of ...In this paper, Schwarz-Pick estimates for high order Fr′echet derivatives of bounded holomorphic functions on three kinds of classical domains are presented. We generalize the early work on Schwarz-Pick estimates of higher order partial derivatives for bounded holomorphic functions on the disk and unit ball.展开更多
The aexercisegexperiment shows that the dumbbell domains,which can eventually contract to circular form and then collapse,should be classified as a kind of dumbbells rather than hard bubbles.Thus dumbbell domains can ...The aexercisegexperiment shows that the dumbbell domains,which can eventually contract to circular form and then collapse,should be classified as a kind of dumbbells rather than hard bubbles.Thus dumbbell domains can be divided into two kinds:ID and HD.Their static characteristics are reported,and typical photos are presented.展开更多
Objective:To explore the meanings and domains for giving communities the capacity to be successful in dengue prevention and control.Methods:One hundred and twenty participants were purposely selected from 4 sub-distri...Objective:To explore the meanings and domains for giving communities the capacity to be successful in dengue prevention and control.Methods:One hundred and twenty participants were purposely selected from 4 sub-districts of 4 provinces in Southern Thailand with a high dengue incidence.Sixty community leaders and sixty non-community leaders participated in this study.In-depth interviews(IDIs),as well as focus group discussions (FGDs) with tape-recorders and note-taking,were used to collect data.All records were transcribed verbatim and analyzed by using the Colaizzi method for content analysis.Results:The findings showed that people view the creation of a sustainable dengue community program as possible only with the support of each community in its entirety:"everyone,every sector,all participating,and with continuing activities." Community capacity for dengue prevention and control was dependent on ten domains:1) stakeholder participation, 2) community leadership,3) a core-activities group,4) a problem-solving needs assessment,5) dengue information transfer,6) resource mobilization,7 ) a sense of community for the dengue problem,8) a dengue network partnership,9) critical dengue situation-management,and 10) continuing dengue prevention and control activities.Conclusion:These community capacity domains can be developed into an assessment tool for the community capacity-building process.Community capacity domains require community leaders and non-community leaders to clarify dengue prevention and control assistance required.展开更多
For domains composed by balls in C^n, this paper studies the boundary behaviour of Cauchy type integrals with discrete holomorphic kernels and the corresponding linear singular integral equation on each piece of smoot...For domains composed by balls in C^n, this paper studies the boundary behaviour of Cauchy type integrals with discrete holomorphic kernels and the corresponding linear singular integral equation on each piece of smooth lower dimensional edges on the boundary of the domain.展开更多
Membrane microdomains or lipid rafts are known to be highly dynamic and to act as selective signal transduction mediators that facilitate interactions between the cell's external and internal environments.Lipid ra...Membrane microdomains or lipid rafts are known to be highly dynamic and to act as selective signal transduction mediators that facilitate interactions between the cell's external and internal environments.Lipid rafts play an important mediating role in the biology of cancer:they have been found in almost all existing experimental cancer models,including colorectal cancer (CRC),and play key regulatory roles in cell migration,metastasis,cell survival and tumor progression.This paper explores the current state of knowledge in this field by highlighting some of the pioneering and recent lipid raft studies performed on different CRC cell lines and human tissue samples.From this literature review,it becomes clear that membrane microdomains appear to be implicated in all key intracellular signaling pathways for lipid metabolism,drug resistance,cell adhesion,cell death,cell proliferation and many other processes in CRC.All signal transduction pathways seem to originate directly from those peculiar lipid islands,thereby orchestrating the colon cancer cells' state and fate.As confirmed by recent animal and preclinical studies in different CRC models,continuing to unravel the structure and function of lipid rafts-including their associated complex signaling pathways-will likely bring us one step closer to better monitoring and treating of colon cancer patients.展开更多
It is more and more important to analyse and process complex data for gaining more valuable knowledge and making more accurate decisions.The multigranulation decision theory based on conditional probability and cost l...It is more and more important to analyse and process complex data for gaining more valuable knowledge and making more accurate decisions.The multigranulation decision theory based on conditional probability and cost loss has the advantage of processing decision-making problems from multi-levels and multi-angles,and the neighbourhood rough set model(NRS)can facilitate the analysis and processing of numerical or mixed type data,and can address the limitation of multigranulation decision-theoretic rough sets(MG-DTRS),which is not easy to cope with complex data.Based on the in-depth study of hybrid-valued decision systems and MG-DTRS models,this study analysed neigh-bourhood MG-DTRS(NMG-DTRS)deeply by fusing MG-DTRS and NRS;a matrix-based approach for approximation sets of NMG-DTRS model was proposed on the basis of the matrix representations of concepts;the positive,boundary and negative domains were constructed from the matrix perspective,and the concept of positive decision recognition rate was introduced.Furthermore,the authors explored the related properties of NMG-DTRS model,and designed and described the corresponding solving algorithms in detail.Finally,some experimental results that were employed not only verified the effectiveness and feasibility of the proposed algorithm,but also showed the relationship between the decision recognition rate and the granularity and threshold.展开更多
In this paper, we study the mapping properties of singular integral operator along surfaces of revolution. We prove Lp bounds (1 < p < ∞) for such singular integral operators as well as for their corresponding ...In this paper, we study the mapping properties of singular integral operator along surfaces of revolution. We prove Lp bounds (1 < p < ∞) for such singular integral operators as well as for their corresponding maximal truncated singular integrals if the singular kernels are allowed to be in certain block spaces.展开更多
基金supported by grants for development of new faculty staff,Ratchadaphiseksomphot Fund,Chulalongkorn University,Thailand.
文摘Objectives This study aimed to explore the research trends,thematic structures,and core competency domains in the field of nursing-related digital and artificial intelligence(AI)technologies.Methods A bibliometric analysis was conducted in accordance with the PRISMA 2020 statement.Peer-reviewed articles published in English from 2015 to 2025 were retrieved from Scopus,Web of Science,and PubMed.Thematic clustering was conducted using the Louvain algorithm and cosine similarity.A subset of 66 frequently cited articles was then qualitatively synthesized to capture core competencies across clusters.Results A total of 83,807 articles were included for bibliometric analysis.Of these,66 articles were chosen for thematic analysis.Five major thematic clusters were identified:remote care in primary settings,oncology and palliative care,nurse education and training,safety and quality in nursing practice,and geriatric and dementia care.Additionally,four competency domains were identified:telehealth and remote communication,health systems and informatics,digital tools in practice,and AI-powered decision support.A clear shift in research focus was observed,with the emphasis transitioning from foundational digital skills before the COVID-19 pandemic to more advanced competencies during the post-pandemic digital transformation,encompassing ethical reasoning,immersive technology use,and AI integration.Conclusions Integrating digital and AI technologies is reshaping nursing practice across various thematic areas and competency domains,highlighting a transition from foundational digital tasks to AI-supported decision-making and ethically informed technology use.This study provides a structured overview of evolving competencies in digital nursing and synthesizes evidence to support future research,curriculum design,and policy planning.
基金the Deanship of Scientific Research at King Khalid University for funding this work through large group under grant number(GRP.2/663/46).
文摘Domain Generation Algorithms(DGAs)continue to pose a significant threat inmodernmalware infrastructures by enabling resilient and evasive communication with Command and Control(C&C)servers.Traditional detection methods-rooted in statistical heuristics,feature engineering,and shallow machine learning-struggle to adapt to the increasing sophistication,linguistic mimicry,and adversarial variability of DGA variants.The emergence of Large Language Models(LLMs)marks a transformative shift in this landscape.Leveraging deep contextual understanding,semantic generalization,and few-shot learning capabilities,LLMs such as BERT,GPT,and T5 have shown promising results in detecting both character-based and dictionary-based DGAs,including previously unseen(zeroday)variants.This paper provides a comprehensive and critical review of LLM-driven DGA detection,introducing a structured taxonomy of LLM architectures,evaluating the linguistic and behavioral properties of benchmark datasets,and comparing recent detection frameworks across accuracy,latency,robustness,and multilingual performance.We also highlight key limitations,including challenges in adversarial resilience,model interpretability,deployment scalability,and privacy risks.To address these gaps,we present a forward-looking research roadmap encompassing adversarial training,model compression,cross-lingual benchmarking,and real-time integration with SIEM/SOAR platforms.This survey aims to serve as a foundational resource for advancing the development of scalable,explainable,and operationally viable LLM-based DGA detection systems.
文摘In this study,the wave motion in elastodynamics for unbounded media is modeled using an unsplit-field perfectly matched layer(PML)formulation that is solved by employing an isogeometric analysis(IGA).In the adopted combination,the non-uniform rational B-spline(NURBS)functions are employed as basis functions.Moreover,the unbounded and artificial domains,defined in the PML method,are contained in a single patch domain.Based on the proposed scheme,the approximation of the geometry problem is set in a new scheme in which the PML’s absorbing and attenuation properties and the description of traveling waves can be represented.This includes a higher continuity and smoother approximation of the computed domain.As high-order NURBS basis functions are non-interpolatory,a penalty method is present to apply a time-dependent displacement load.The performance of the NURBS-based PML is analyzed through numerical examples for 1D and 2D domains,considering homogeneous and heterogeneous media.Further,we verify the long-time numerical stability of the present method.The developed method can be used to simulate hypothetical stratified domains commonly encountered in soil-structure interaction analyses.
文摘In this paper,we study the weighted higher order semilinear equation in an exterior domain(-△)^(m)u=|x|^(α)g(u)in R^(N)\B_(R_(0)),where N≥1,m≥2 are integers,α>-2m,g is a continuous and nondecreasing function in(0,+∞)and positive in(0,+∞),B_(R_(0))is the ball of the radius R0 centered at the origin.We prove that a positive supersolution of the problem which verifies(-△)_(i)u>0 in R^(N)\B_(R_(0))(i=0,…,m-1)exists if and only if N>2m and∫_(0)^(δ)g(t)/t^(2(N-m)+α/N-2m)dt<∞,,for someδ>0.We further obtain some existence and nonexistence results for the positive solution to the Dirichlet problem when g(u)=u^(p)with p>1,by using the Pohozaev identity and an embedding lemma of radial Sobolev spaces.
基金supported by National Natural Science Foundation of China (No. 32371810)China Postdoctoral Science Foundation (2023M731702)+5 种基金National Key Research and Development Program of China (2023YFB4203702)the Foundation Research Project of Jiangsu Province (BK20221338)Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest ResourcesInternational Innovation Center for Forest Chemicals and Materials,Nanjing Forestry Universitymerit-based funding for Nanjing innovation and technology projectsthe Foundation of Jiangsu Key Lab of Biomass Energy and Material (JSBEM-S-202101)
文摘Natural biomass-derived carbon material is one promising alternative to traditional graphene-based catalyst for oxygen electrocatalysis.However,their electrocatalytic performance were constrained by the limited modulating strategy.Herein,using N-doped commercial coconut shell-derived activated carbon(AC)as catalyst model,the controllably enhanced sp^(2)-C domains,through an flash Joule heating process,effectively improve the edge defect density and overall graphitization degree of AC catalyst,which tunes the electronic structure of N configurations and accelerates electron transfer,leading to excellent oxygen reduction reaction performance(half-wave potential of 0.884 VRHE,equivalent to commercial 20%Pt/C,with a higher kinetic current density of 5.88 mA cm^(−2))and oxygen evolution reaction activity(overpotential of 295 mV at 10 mA cm^(2)).In a Zn-air battery,the catalyst shows outstanding cycle stability(over 1200 h)and a peak power density of 121 mW cm^(−2),surpassing commercial Pt/C and RuO_(2)catalysts.Density functional theory simulation reveals that the enhanced catalytic activity arises from the axial regulation of local sp^(2)-C domains.This work establishes a robust strategy for sp^(2)-C domain modulation,offering broad applicability in natural biomass-based carbon catalysts for electrocatalysis.
基金supported by National Natural Science Foundation of China(Grant Nos.62473277,62473275,62133004,52105072,and 62073230)Jiangsu Provincial Outstanding Youth Program(Grant No.BK20230072)+5 种基金National Key R&D Program of China(Grant Nos.2022YFC3802302 and 2023YFB4705600)Suzhou Industrial Foresight and Key Core Technology Project(Grant No.SYC2022044)Zhejiang Provincial Natural Science Foundation of China(Grant No.LZ24E050004)Shenzhen Polytechnic High-level Talent Start-up Project(Grant No.6023330006K)Shenzhen Science and Technology Program(Grant No.JCYJ20210324132810026)a Grant from Open Foundation of the State Key Laboratory of Fluid Power and Mechatronic Systems,Grants from Jiangsu QingLan Project and Jiangsu 333 high-level talents.
文摘Soft robots, inspired by the flexibility and versatility of biological organisms, have potential in a variety of applications. Recent advancements in magneto-soft robots have demonstrated their abilities to achieve precise remote control through magnetic fields, enabling multi-modal locomotion and complex manipulation tasks. Nonetheless, two main hurdles must be overcome to advance the field: developing a multi-component substrate with embedded magnetic particles to ensure the requisite flexibility and responsiveness, and devising a cost-effective,straightforward method to program three-dimensional distributed magnetic domains without complex processing and expensive machinery. Here, we introduce a cost-effective and simple heat-assisted in-situ integrated molding fabrication method for creating magnetically driven soft robots with three-dimensional programmable magnetic domains. By synthesizing a composite material with neodymium-iron-boron(NdFeB) particles embedded in a polydimethylsiloxane(PDMS) and Ecoflex matrix(PDMS:Ecoflex = 1:2 mass ratio, 50% magnetic particle concentration), we achieved an optimized balance of flexibility, strength, and magnetic responsiveness. The proposed heat-assisted in-situ magnetic domains programming technique,performed at an experimentally optimized temperature of 120℃, resulted in a 2 times magnetization strength(9.5 mT) compared to that at 20℃(4.8 m T), reaching a saturation level comparable to a commercial magnetizer. We demonstrated the versatility of our approach through the fabrication of six kinds of robots, including two kinds of two-dimensional patterned soft robots(2D-PSR), a circular six-pole domain distribution magnetic robot(2D-CSPDMR), a quadrupedal walking magnetic soft robot(QWMSR), an object manipulation robot(OMR), and a hollow thin-walled spherical magneto-soft robot(HTWSMSR). The proposed method provides a practical solution to create highly responsive and adaptable magneto-soft robots.
基金Supported by the National Natural Science Foundation of China(12301101)the Guangdong Basic and Applied Basic Research Foundation(2022A1515110019 and 2020A1515110585)。
文摘In this paper,the Paley-Wiener theorem is extended to the analytic function spaces with general weights.We first generalize the theorem to weighted Hardy spaces Hp(0<p<∞)on tube domains by constructing a sequence of L^(1)functions converging to the given function and verifying their representation in the form of Fourier transform to establish the desired result of the given function.Applying this main result,we further generalize the Paley-Wiener theorem for band-limited functions to the analytic function spaces L^(p)(0<p<∞)with general weights.
基金Supported by NSFC (No.12361027)NSF of Inner Mongolia (No.2018MS01021)+1 种基金NSF of Shandong Province (No.ZR2020QA009)Science and Technology Innovation Program for Higher Education Institutions of Shanxi Province (No.2024L533)。
文摘In this paper,we give a complete characterization of all self-adjoint domains of odd order differential operators on two intervals.These two intervals with all four endpoints are singular(one endpoint of each interval is singular or all four endpoints are regulars are the special cases).And these extensions yield"new"self-adjoint operators,which involve interactions between the two intervals.
文摘In this paper,we extend the definition of almost starlike mappings of order 1/2 on B n to the almost starlike mappings of order α on the bounded starlike circular domains in C n,and give the growth theorem of it. This type of domain on which we discuss is rather general,in the sense that the domain must be starlike if there exists a normalized biholomorphic starlike mapping on it.
基金supported by Zhejiang Provincial Natural Science Foundation of China(Grant No.LZ25A040005)the National Natural Science Foundation of China(Grant No.11674287).
文摘The partitioning of membrane proteins into lipid domains in cellular membranes is closely associated with the realization of the protein functions and it is influenced by various factors such as the post-translational modification of palmitoylation.However,the molecular mechanism of the effect of palmitoylation on membrane protein partitioning into the lipid domains remains elusive.In this work,taking human peripheral myelin protein 22(PMP22)as an example,we employ coarse-grained molecular dynamics simulations to investigate the partitioning of both the natural PMP22 and the palmitoylated PMP22(pal-PMP22)into the lipid domains of model myelin membranes.The results indicate that palmitoylation drives PMP22 to localize at the boundary of the liquid-ordered(Lo)and liquid-disordered(Ld)domains and increases the possibility of PMP22 partitioning into the Lo domains by changing the hydrophobic length of the proteins and perturbing the ordered packing of tails of the saturated lipids in the Lo domains.This work offers some novel insights into the role of palmitoylation in modulating the function of membrane proteins in cellular membranes.
文摘The authors obtain the growth and covering theorems for strongly starlike mappings of order α on bounded starlike circular domains.This kind of domain discussed is rather general,since the domain must be starlike if exists a normalized biholomorphic starlike mapping on it.
基金Foundation item： Supported by the National Natural Science Foundation of China（11001074, 11061015, 11101124）
文摘In this paper, we give a property of normalized biholomorphic convex mappings on the first, second and third classical domains: for any Z0 belongs to the classical domains,f maps each neighbourhood with the center Z0, which is contained in the classical domains,to a convex domain.
文摘In many metazoan species, germ cell formation requires the germ plasm, a specialized cytoplasm which often con-tains electron dense structures. Genes required for germ cell formation in Drosophila have been isolated predominantlyin screens for maternal-effect mutations. One such gene is tudor (tud); without proper tud function germ cell formationdoes not occur. Unlike other genes involved in Drosophila germ cell specification tud is dispensable for other somaticfunctions such as abdominal patterning. It is not known how TUD contributes at a molecular level to germ cell forma-tion but in tud mutants, polar granule formation is severely compromised, and mitochondrially encoded ribosomal RNAsdo not localize to the polar granule. TUD is composed of 11 repeats of the protein motif called the Tudor domain. Thereare similar proteins to TUD in the germ line of other metazoan species including mice. Probable vertebrate orthologuesof Drosophila genes involved in germ cell specification will be discussed.
基金supported by National Natural Science Foundation of China (10871145 10926066)+1 种基金Doctoral Program Foundation of the Ministry of Education of China (20090072110053)Natural Science Foundation of Zhejiang Province (Y6100007)
文摘In this paper, Schwarz-Pick estimates for high order Fr′echet derivatives of bounded holomorphic functions on three kinds of classical domains are presented. We generalize the early work on Schwarz-Pick estimates of higher order partial derivatives for bounded holomorphic functions on the disk and unit ball.
文摘The aexercisegexperiment shows that the dumbbell domains,which can eventually contract to circular form and then collapse,should be classified as a kind of dumbbells rather than hard bubbles.Thus dumbbell domains can be divided into two kinds:ID and HD.Their static characteristics are reported,and typical photos are presented.
基金supported by the Thailand Nursing and Midwifery Councilthe Graduate School of Chulalongkorn University
文摘Objective:To explore the meanings and domains for giving communities the capacity to be successful in dengue prevention and control.Methods:One hundred and twenty participants were purposely selected from 4 sub-districts of 4 provinces in Southern Thailand with a high dengue incidence.Sixty community leaders and sixty non-community leaders participated in this study.In-depth interviews(IDIs),as well as focus group discussions (FGDs) with tape-recorders and note-taking,were used to collect data.All records were transcribed verbatim and analyzed by using the Colaizzi method for content analysis.Results:The findings showed that people view the creation of a sustainable dengue community program as possible only with the support of each community in its entirety:"everyone,every sector,all participating,and with continuing activities." Community capacity for dengue prevention and control was dependent on ten domains:1) stakeholder participation, 2) community leadership,3) a core-activities group,4) a problem-solving needs assessment,5) dengue information transfer,6) resource mobilization,7 ) a sense of community for the dengue problem,8) a dengue network partnership,9) critical dengue situation-management,and 10) continuing dengue prevention and control activities.Conclusion:These community capacity domains can be developed into an assessment tool for the community capacity-building process.Community capacity domains require community leaders and non-community leaders to clarify dengue prevention and control assistance required.
基金Project supported by the National Science Foundation of China (10271097)
文摘For domains composed by balls in C^n, this paper studies the boundary behaviour of Cauchy type integrals with discrete holomorphic kernels and the corresponding linear singular integral equation on each piece of smooth lower dimensional edges on the boundary of the domain.
基金Supported by The Australian Research Council through Linkage Infrastructure, Equipment and Facilities grants, No.LE0775598the ARC/NHMRC FABLS Research Network, No.RN0460002
文摘Membrane microdomains or lipid rafts are known to be highly dynamic and to act as selective signal transduction mediators that facilitate interactions between the cell's external and internal environments.Lipid rafts play an important mediating role in the biology of cancer:they have been found in almost all existing experimental cancer models,including colorectal cancer (CRC),and play key regulatory roles in cell migration,metastasis,cell survival and tumor progression.This paper explores the current state of knowledge in this field by highlighting some of the pioneering and recent lipid raft studies performed on different CRC cell lines and human tissue samples.From this literature review,it becomes clear that membrane microdomains appear to be implicated in all key intracellular signaling pathways for lipid metabolism,drug resistance,cell adhesion,cell death,cell proliferation and many other processes in CRC.All signal transduction pathways seem to originate directly from those peculiar lipid islands,thereby orchestrating the colon cancer cells' state and fate.As confirmed by recent animal and preclinical studies in different CRC models,continuing to unravel the structure and function of lipid rafts-including their associated complex signaling pathways-will likely bring us one step closer to better monitoring and treating of colon cancer patients.
基金the Universities Natural Science Key Project of Anhui Province,Grant/Award Number:KJ2020A0637。
文摘It is more and more important to analyse and process complex data for gaining more valuable knowledge and making more accurate decisions.The multigranulation decision theory based on conditional probability and cost loss has the advantage of processing decision-making problems from multi-levels and multi-angles,and the neighbourhood rough set model(NRS)can facilitate the analysis and processing of numerical or mixed type data,and can address the limitation of multigranulation decision-theoretic rough sets(MG-DTRS),which is not easy to cope with complex data.Based on the in-depth study of hybrid-valued decision systems and MG-DTRS models,this study analysed neigh-bourhood MG-DTRS(NMG-DTRS)deeply by fusing MG-DTRS and NRS;a matrix-based approach for approximation sets of NMG-DTRS model was proposed on the basis of the matrix representations of concepts;the positive,boundary and negative domains were constructed from the matrix perspective,and the concept of positive decision recognition rate was introduced.Furthermore,the authors explored the related properties of NMG-DTRS model,and designed and described the corresponding solving algorithms in detail.Finally,some experimental results that were employed not only verified the effectiveness and feasibility of the proposed algorithm,but also showed the relationship between the decision recognition rate and the granularity and threshold.
文摘In this paper, we study the mapping properties of singular integral operator along surfaces of revolution. We prove Lp bounds (1 < p < ∞) for such singular integral operators as well as for their corresponding maximal truncated singular integrals if the singular kernels are allowed to be in certain block spaces.
