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ON THE MEASURE CONCENTRATION OF INFINITELY DIVISIBLE DISTRIBUTIONS
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作者 Jing ZHANG Zechun HU Wei SUN 《Acta Mathematica Scientia》 2025年第2期473-492,共20页
Let I be the set of all infinitely divisible random variables with finite second moments,I_(0)={X∈I;Var(X)>0},P_(I)=inf_(x∈I)P{|X-E[X]|≤√Var(X)}and P_(I_(0))=inf P{|X-E[X]|<√Var(X)}.Firstly,we prove that P_... Let I be the set of all infinitely divisible random variables with finite second moments,I_(0)={X∈I;Var(X)>0},P_(I)=inf_(x∈I)P{|X-E[X]|≤√Var(X)}and P_(I_(0))=inf P{|X-E[X]|<√Var(X)}.Firstly,we prove that P_(I)≥P_(I_(0))>0.Secondly,we find_(x∈I_(0))the exact values of inf P{|X-E[X]|≤√Var(X)}and inf P{|X-E[X]|<√Var(X)}for the cases that J is the set of all geometric random variables,symmetric geometric random variables,Poisson random variables and symmetric Poisson random variables,respectively.As a consequence,we obtain that P_(I)≤e^(-1)^(∞)∑_(k=0)1/2^(2k)(k!)^(2)≈0.46576 and P_(I_(0))≤e^(-1)≈0.36788. 展开更多
关键词 measure concentration infinitely divisible distribution geometric distribution Poisson distribution Berry-Esseen theorem
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Optimal Planning of Multiple PV-DG in Radial Distribution Systems Using Loss Sensitivity Analysis and Genetic Algorithm
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作者 A. Elkholy 《Journal of Power and Energy Engineering》 2025年第2期1-22,共22页
This paper introduces an optimized planning approach for integrating photovoltaic as distributed generation (PV-DG) into the radial distribution power systems, utilizing exhaustive load flow (ELF), loss sensitivity fa... This paper introduces an optimized planning approach for integrating photovoltaic as distributed generation (PV-DG) into the radial distribution power systems, utilizing exhaustive load flow (ELF), loss sensitivity factor (LSF), genetic algorithms (GA) methods, and numerical method based on LSF. The methodology aims to determine the optimal allocation and sizing of multiple PV-DG to minimize power loss through time series power flow analysis. An approach utilizing continuous sensitivity analysis is developed and inherently leverages power flow and loss equations to compute LSF of all buses in the system towards employing a dynamic PV-DG model for more accurate results. The algorithm uses a numerical grid search method to optimize PV-DG placement in a power distribution system, focusing on minimizing system losses. It combines iterative analysis, sensitivity assessment, and comprehensive visualization to identify and present the optimal PV-DG configurations. The present-ed algorithms are verified through co-simulation framework combining MATLAB and OpenDSS to carry out analysis for 12-bus radial distribution test system. The proposed numerical method is compared with other algorithms, such as ELF, LSF methods, and Genetic Algorithms (GA). Results show that the proposed numerical method performs well in comparison with LSF and ELF solutions. 展开更多
关键词 Photovoltaic Systems distributed Generation Multiple Allocation and Sizing Power Losses Radial distribution System Genetic Algorithm
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Optimization of Reconfiguration and Resource Allocation for Distributed Generation and Capacitor Banks Using NSGA-Ⅱ:A Multi-Scenario Approach
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作者 Tareq Hamadneh Belal Batiha +3 位作者 Frank Werner Mehrdad Ahmadi Kamarposhti Ilhami Colak El Manaa Barhoumi 《Computer Modeling in Engineering & Sciences》 2025年第5期1519-1548,共30页
Reconfiguration,as well as optimal utilization of distributed generation sources and capacitor banks,are highly effective methods for reducing losses and improving the voltage profile,or in other words,the power quali... Reconfiguration,as well as optimal utilization of distributed generation sources and capacitor banks,are highly effective methods for reducing losses and improving the voltage profile,or in other words,the power quality in the power distribution system.Researchers have considered the use of distributed generation resources in recent years.There are numerous advantages to utilizing these resources,the most significant of which are the reduction of network losses and enhancement of voltage stability.Non-dominated Sorting Genetic Algorithm II(NSGA-II),Multi-Objective Particle Swarm Optimization(MOPSO),and Intersect Mutation Differential Evolution(IMDE)algorithms are used in this paper to perform optimal reconfiguration,simultaneous location,and capacity determination of distributed generation resources and capacitor banks.Three scenarios were used to replicate the studies.The reconfiguration of the switches,as well as the location and determination of the capacitor bank’s optimal capacity,were investigated in this scenario.However,in the third scenario,reconfiguration,and determining the location and capacity of the Distributed Generation(DG)resources and capacitor banks have been carried out simultaneously.Finally,the simulation results of these three algorithms are compared.The results indicate that the proposed NSGAII algorithm outperformed the other two multi-objective algorithms and was capable of maintaining smaller objective functions in all scenarios.Specifically,the energy losses were reduced from 211 to 51.35 kW(a 75.66%reduction),119.13 kW(a 43.54%reduction),and 23.13 kW(an 89.04%reduction),while the voltage stability index(VSI)decreased from 6.96 to 2.105,1.239,and 1.257,respectively,demonstrating significant improvement in the voltage profile. 展开更多
关键词 distribution network reconfiguration energy losses distributed generations capacitor banks NSGAII
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Peer-to-peer transaction with voltage management strategy in distribution network considering trading risk
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作者 Lei Dong Kuang Zhang +3 位作者 Shiming Zhang Tao Zhang Ye Li Ji Qiao 《Global Energy Interconnection》 2025年第4期685-699,共15页
P2P trading is driving the decentralization of the electricity market,the autonomy and privacy requirements of prosumers may intro-duce safety risks such as voltage violations.Existing security management methods base... P2P trading is driving the decentralization of the electricity market,the autonomy and privacy requirements of prosumers may intro-duce safety risks such as voltage violations.Existing security management methods based on price guidance may face unsolvable situa-tions in trading scenarios and have difficulty assessing the impact of P2P transactions on voltage security.To this end,this paper proposes a novel distribution system operator(DSO)-prosumers bi-level optimization framework incorporating the dynamic operating envelope(DOE)and risk coefficient-based network usage charge(RC-NUC).In the upper-level,the DOE is employed for dynamic voltage man-agement to prevent violations while the RC-NUC further guides prosumers to engage in grid-friendly transactions.The lower-level decen-tralized market enables prosumers to optimize trading decisions autonomously.Only price signals and energy quantities are exchanged between the two levels,ensuring the privacy of both parties.Additionally,an alternating direction method of multipliers(ADMM)with adaptive penalty factor is introduced to improve computational efficiency.Case studies on a modified IEEE 33-bus system demonstrate that the proposed method reduces voltage violation risks by 18.31%and enhances trading efficiency by 32.3%.These results highlight the feasibility and effectiveness of the approach in advancing secure and efficient distributed energy transactions. 展开更多
关键词 P2P transaction DOE RC-NUC distribution network distributed algorithm
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Patterns of genetic diversity in five species of Passeriformes co-distributed in an environmental gradient
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作者 Marcela Restrepo-Arias Héctor F.Rivera-Gutiérrez +2 位作者 Iván Darío Soto-Calderón Ernesto Pérez-Collazos Catalina González-Quevedo 《Avian Research》 2025年第3期519-530,共12页
Understanding the evolutionary processes that influence the distribution of genetic diversity in natural populations is a key issue in evolutionary biology. Both species' distribution ranges and environmental grad... Understanding the evolutionary processes that influence the distribution of genetic diversity in natural populations is a key issue in evolutionary biology. Both species' distribution ranges and environmental gradients can influence this diversity through mechanisms such as gene flow, selection, and genetic drift. To explore how these forces interact, we assessed neutral and adaptive genetic variation in three widely distributed and two narrowly distributed bird species co-occurring along the Cauca River canyon in Antioquia, Colombia—a region of pronounced environmental heterogeneity. We sampled individuals across eight sites spanning the canyon's gradient and analyzed genetic diversity and structure using microsatellites and toll-like receptors (TLRs), a gene family involved in innate immunity. Widely distributed species consistently exhibited higher genetic diversity at both marker types compared to their narrowly distributed counterparts. Although we did not find a significant relationship between microsatellite heterozygosity and TLR heterozygosity, we evidenced a negative trend for widely distributed species and a positive trend for narrowly distributed species. This result suggests that there is a stronger effect of genetic drift in narrowly distributed species. Our results highlight the role of distribution range in maintaining genetic diversity and suggest that environmental gradients, by interacting with gene flow and selection, may influence patterns of adaptive variation. 展开更多
关键词 Adaptive genetic diversity Microsatellites Neutral genetic diversity Restricted distribution Tol-ike receptor Wide distribution
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Distributed State and Fault Estimation for Cyber-Physical Systems Under DoS Attacks
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作者 Limei Liang Rong Su Haotian Xu 《IEEE/CAA Journal of Automatica Sinica》 2025年第1期261-263,共3页
Dear Editor,The letter deals with the distributed state and fault estimation of the whole physical layer for cyber-physical systems(CPSs) when the cyber layer suffers from DoS attacks. With the advancement of embedded... Dear Editor,The letter deals with the distributed state and fault estimation of the whole physical layer for cyber-physical systems(CPSs) when the cyber layer suffers from DoS attacks. With the advancement of embedded computing, communication and related hardware technologies, CPSs have attracted extensive attention and have been widely used in power system, traffic network, refrigeration system and other fields. 展开更多
关键词 cyber physical systems refrigeration system traffic network dos attacks distributed state fault estimation embedded computing power system distributed state estimation
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Spatial monitoring of curved geostructures using distributed Brillouin sensing:A state-of-the-art review
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作者 Shaoqiu Zhang Chao Wang +2 位作者 Cleitus Antony Qinglai Zhang Zili Li 《Intelligent Geoengineering》 2025年第1期35-53,共19页
Curved geostructures,such as tunnels,are commonly encountered in geotechnical engineering and are critical to maintaining structural stability.Ensuring their proper performance through field monitoring during their se... Curved geostructures,such as tunnels,are commonly encountered in geotechnical engineering and are critical to maintaining structural stability.Ensuring their proper performance through field monitoring during their service life is essential for the overall functionality of geotechnical infrastructure.Distributed Brillouin sensing(DBS)is increasingly applied in geotechnical projects due to its ability to acquire spatially continuous strain and temperature distributions over distances of up to 150 km using a single optical fibre.However,limited by the complex operations of distributed optic fibre sensing(DFOS)sensors in curved structures,previous reports about exploiting DBS in geotechnical structural health monitoring(SHM)have mostly been focused on flat surfaces.The lack of suitable DFOS installation methods matched to the spatial characteristics of continuous monitoring is one of the major factors that hinder the further application of this technique in curved structures.This review paper starts with a brief introduction of the fundamental working principle of DBS and the inherent limitations of DBS being used on monitoring curved surfaces.Subsequently,the state-of-the-art installation methods of optical fibres in curved structures are reviewed and compared to address the most suitable scenario of each method and their advantages and disadvantages.The installation challenges of optical fibres that can highly affect measurement accuracy are also discussed in the paper. 展开更多
关键词 distributed Brillouin sensing Structural health monitoring distributed fibre optic sensing Curved geostructures Field instrumentation
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Matching the light and nitrogen distributions in the maize canopy to achieve high yield and high radiation use efficiency
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作者 Xiaoxia Guo Wanmao Liu +6 位作者 Yunshan Yang Guangzhou Liu Bo Ming Ruizhi Xie Keru Wang Shaokun Li Peng Hou 《Journal of Integrative Agriculture》 2025年第4期1424-1435,共12页
The distributions of light and nitrogen within a plant's canopy reflect the growth adaptation of crops to the environment and are conducive to improving the carbon assimilation ability.So can the yield in crop pro... The distributions of light and nitrogen within a plant's canopy reflect the growth adaptation of crops to the environment and are conducive to improving the carbon assimilation ability.So can the yield in crop production be maximized by improving the light and nitrogen distributions without adding any additional inputs?In this study,the effects of different nitrogen application rates and planting densities on the canopy light and nitrogen distributions of two highyielding maize cultivars(XY335 and DH618)and the regulatory effects of canopy physiological characteristics on radiation use efficiency(RUE)and yield were studied based on high-yield field experiments in Qitai,Xinjiang Uygur Autonomous Region,China,during 2019 and 2020.The results showed that the distribution of photosynthetically active photon flux density(PPFD)in the maize canopy decreased from top to bottom,while the vertical distribution of specific leaf nitrogen(SLN)initially increased and then decreased from top to bottom in the canopy.When SLN began to decrease,the PPDF values of XY335 and DH618 were 0.5 and 0.3,respectively,corresponding to 40.6 and49.3%of the total leaf area index(LAI).Nitrogen extinction coefficient(K_(N))/light extinction coefficient(K_(L))ratio in the middle and lower canopy of XY335(0.32)was 0.08 higher than that of DH618(0.24).The yield and RUE of XY335(17.2 t ha^(-1)and 1.8g MJ^(-1))were 7.0%(1.1 t ha^(-1))and 13.7%(0.2 g MJ^(-1))higher than those of DH618(16.1 t ha^(-1)and 1.6 g MJ^(-1)).Therefore,better light conditions(where the proportion of LAI in the upper and middle canopy was small)improved the light distribution when SLN started to decline,thus helping to mobilize the nitrogen distribution and maintain a high K_(N)and K_(N)/K_(L)ratio.In addition,K_(N)/K_(L)was a key parameter for yield improvement when the maize nutrient requirements were met at 360 kg N ha^(-1).At this level,an appropriately optimized high planting density could promote nitrogen utilization and produce higher yields and greater efficiency.The results of this study will be important for achieving high maize yields and the high efficiency cultivation and breeding of maize in the future. 展开更多
关键词 MAIZE canopy N distribution canopy light distribution radiation use efficiency
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Coordinated optimization of P2P energy trading and network operation for active distribution network with multi-microgrids
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作者 Peishuai Li Yihan Wang +3 位作者 Tao Zheng Yulong Jin Weizhi Yuan Wenwen Guo 《Global Energy Interconnection》 2025年第3期474-485,共12页
Microgrids (MGs) and active distribution networks (ADNs) are important platforms for distributed energy resource (DER) consumption. The increasing penetration of DERs has motivated the development ADNs coupled with MG... Microgrids (MGs) and active distribution networks (ADNs) are important platforms for distributed energy resource (DER) consumption. The increasing penetration of DERs has motivated the development ADNs coupled with MGs. This paper proposes a distributedco-optimization method for peer-to-peer (P2P) energy trading and network operation for an ADN integrated with multiple microgrids(MMGs). A framework that optimizes P2P energy trading among MMGs and ADN operations was first established. Subsequently, anenergy management model that aims to minimize the operation and energy trading costs was constructed for each MG. Accordingly, theMMGs’ cooperative game model was established based on Nash bargaining theory to incentivize each stakeholder to participate in P2Penergy trading, and a distributed solution method based on the alternating direction method of multipliers was developed. Moreover, analgorithm that adjusts the amount of energy trading between the ADN and MG is proposed to ensure safe operation of the distributionnetwork. With the communication between the MG and ADN, the MMGs’ P2P trading and ADN operations are optimized in a coordinated manner. Finally, numerical simulations were conducted to verify the accuracy and effectiveness of the proposed method. 展开更多
关键词 Peer-to-peer energy trading Game theory distributed algorithm distribution network operation
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Towards the creation of an inverse electron distribution function in two-chamber inductively coupled plasma discharges
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作者 Ying WANG Nie CHEN +4 位作者 Jingfeng YAO Evgeniy BOGDANOV Anatoly KUDRYAVTSEV Chengxun YUAN Zhongxiang ZHOU 《Plasma Science and Technology》 2025年第5期122-128,共7页
This work continues the studies on searching for plasma media with the inverse electron energy distribution function(EEDF)and providing recommendations for setting up subsequent experiments.The inverse EEDF is a distr... This work continues the studies on searching for plasma media with the inverse electron energy distribution function(EEDF)and providing recommendations for setting up subsequent experiments.The inverse EEDF is a distribution function that increases with an increase in energy at zero electron energy.The inverse EEDF plays a central role in the problem of negative conductivity.Based on the previously obtained criterion for the formation of an inverse EEDF in a spatially inhomogeneous plasma,a heuristic method is proposed that allows one to avoid resource-intensive calculations for spatially two-dimensional(2D)kinetic modeling on a large array of different glow discharges.It is shown that the conditions for EEDF inversion can be realized in two-chamber discharge structures due to violating the known Boltzmann distribution for electron density.The theoretical conclusions are validated by numerical modeling of lowpressure two-chamber inductively-coupled plasma(ICP)discharges in the COMSOL Multiphysics environment.As a result,areas of conditions with inverse EEDF were found for subsequent detailed kinetic analysis and experimental studies. 展开更多
关键词 electron kinetics nonlocal electron distribution function gas discharge Boltzmann kinetic equation inverse electron distribution function inductively coupled plasma
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Novel Low-Carbon Optimal Operation Method for Flexible Distribution Network Based on Carbon Emission Flow
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作者 Chao Gao Kai Niu +3 位作者 Wenjing Chen Changwei Wang Yabin Chen Rui Qu 《Energy Engineering》 2025年第2期785-803,共19页
With the widespread implementation of distributed generation(DG)and the integration of soft open point(SOP)into the distribution network(DN),the latter is steadily transitioning into a flexible distribution network(FD... With the widespread implementation of distributed generation(DG)and the integration of soft open point(SOP)into the distribution network(DN),the latter is steadily transitioning into a flexible distribution network(FDN),the calculation of carbon flow distribution in FDN is more difficult.To this end,this study constructs a model for low-carbon optimal operations within the FDN on the basis of enhanced carbon emission flow(CEF).First,the carbon emission characteristics of FDNs are scrutinized and an improved method for calculating carbon flow within these networks is proposed.Subsequently,a model for optimizing low-carbon operations within FDNs is formulated based on the refined CEF,which merges the specificities of DG and intelligent SOP.Finally,this model is scrutinized using an upgraded IEEE 33-node distribution system,a comparative analysis of the cases reveals that when DG and SOP are operated in a coordinated manner in the FDN,with the cost of electricity generation was reduced by 40.63 percent and the cost of carbon emissions by 10.18 percent.The findings indicate that the judicious optimization of areas exhibiting higher carbon flow rates can effectively enhance the economic efficiency of DN operations and curtail the carbon emissions of the overall network. 展开更多
关键词 Flexible distribution network carbon emission flow distributed generation soft open points
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The compound class of exponentiated power Lindley power series distribution:properties and applications
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作者 Morad Alizadeh Seyed Fazel Bagher +2 位作者 HOU Jun-cheng Saralees Nadarajah Ali Shaban 《Applied Mathematics(A Journal of Chinese Universities)》 2025年第2期255-275,共21页
We introduce a new generalization of the exponentiated power Lindley distribution,called the exponentiated power Lindley power series(EPLPS)distribution.The new distribution arises on a latent complementary risks scen... We introduce a new generalization of the exponentiated power Lindley distribution,called the exponentiated power Lindley power series(EPLPS)distribution.The new distribution arises on a latent complementary risks scenario,in which the lifetime associated with a particular risk is not observable;rather,we observe only the maximum lifetime value among all risks.The distribution exhibits decreasing,increasing,unimodal and bathtub shaped hazard rate functions,depending on its parameters.Several properties of the EPLPS distribution are investigated.Moreover,we discuss maximum likelihood estimation and provide formulas for the elements of the Fisher information matrix.Finally,applications to three real data sets show the flexibility and potentiality of the EPLPS distribution. 展开更多
关键词 exponentiated power Lindley distribution Fisher's information matrix hazard rate function model selection criteria power series distributions residual life function
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Distributed bearing-only target tracking algorithm based on variational Bayesian inference under random measurement anomalies
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作者 YANG Haoran CHEN Yu +1 位作者 HU Zhentao JIA Haoqian 《High Technology Letters》 2025年第1期86-94,共9页
A distributed bearing-only target tracking algorithm based on variational Bayesian inference(VBI)under random measurement anomalies is proposed for the problem of adverse effect of random measurement anomalies on the ... A distributed bearing-only target tracking algorithm based on variational Bayesian inference(VBI)under random measurement anomalies is proposed for the problem of adverse effect of random measurement anomalies on the state estimation accuracy of moving targets in bearing-only tracking scenarios.Firstly,the measurement information of each sensor is complemented by using triangulation under the distributed framework.Secondly,the Student-t distribution is selected to model the measurement likelihood probability density function,and the joint posteriori probability density function of the estimated variables is approximately decoupled by VBI.Finally,the estimation results of each local filter are sent to the fusion center and fed back to each local filter.The simulation results show that the proposed distributed bearing-only target tracking algorithm based on VBI in the presence of abnormal measurement noise comprehensively considers the influence of system nonlinearity and random anomaly of measurement noise,and has higher estimation accuracy and robustness than other existing algorithms in the above scenarios. 展开更多
关键词 bearing-only target tracking(BOTT) variational Bayesian inference(VBI) Student-t distribution cubature Kalman filter(CKF) distributed fusion
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Distributed Cooperative Regulation for Networked Re-Entrant Manufacturing Systems
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作者 Chenguang Liu Qing Gao +1 位作者 Wei Wang Jinhu Lü 《IEEE/CAA Journal of Automatica Sinica》 2025年第3期636-638,共3页
Dear Editor,This letter focuses on the distributed cooperative regulation problem for a class of networked re-entrant manufacturing systems(RMSs).The networked system is structured with a three-tier architecture:the p... Dear Editor,This letter focuses on the distributed cooperative regulation problem for a class of networked re-entrant manufacturing systems(RMSs).The networked system is structured with a three-tier architecture:the production line,the manufacturing layer and the workshop layer.The dynamics of re-entrant production lines are governed by hyperbolic partial differential equations(PDEs)based on the law of mass conservation. 展开更多
关键词 production line networked re entrant manufacturing systems three tier architecture production linethe distributed cooperative regulation hyperbolic partial differential equations pdes based distributed cooperative regulation problem manufacturing layer
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Distributed stochastic model predictive control for energy dispatch with distributionally robust optimization
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作者 Mengting LIN Bin LI C.C.ECATI 《Applied Mathematics and Mechanics(English Edition)》 2025年第2期323-340,共18页
A chance-constrained energy dispatch model based on the distributed stochastic model predictive control(DSMPC)approach for an islanded multi-microgrid system is proposed.An ambiguity set considering the inherent uncer... A chance-constrained energy dispatch model based on the distributed stochastic model predictive control(DSMPC)approach for an islanded multi-microgrid system is proposed.An ambiguity set considering the inherent uncertainties of renewable energy sources(RESs)is constructed without requiring the full distribution knowledge of the uncertainties.The power balance chance constraint is reformulated within the framework of the distributionally robust optimization(DRO)approach.With the exchange of information and energy flow,each microgrid can achieve its local supply-demand balance.Furthermore,the closed-loop stability and recursive feasibility of the proposed algorithm are proved.The comparative results with other DSMPC methods show that a trade-off between robustness and economy can be achieved. 展开更多
关键词 distributed stochastic model predictive control(DSMPC) distributionally robust optimization(DRO) islanded multi-microgrid energy dispatch strategy
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Unveiling the relationship between Fabry-Perot laser structures and optical field distribution via symbolic regression
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作者 LI Wenqiang WU Min +2 位作者 LI Weijun HAO Meilan YU Lina 《Optoelectronics Letters》 2025年第3期149-154,共6页
In recent years,machine learning(ML)techniques have been shown to be effective in accelerating the development process of optoelectronic devices.However,as"black box"models,they have limited theoretical inte... In recent years,machine learning(ML)techniques have been shown to be effective in accelerating the development process of optoelectronic devices.However,as"black box"models,they have limited theoretical interpretability.In this work,we leverage symbolic regression(SR)technique for discovering the explicit symbolic relationship between the structure of the optoelectronic Fabry-Perot(FP)laser and its optical field distribution,which greatly improves model transparency compared to ML.We demonstrated that the expressions explored through SR exhibit lower errors on the test set compared to ML models,which suggests that the expressions have better fitting and generalization capabilities. 展开更多
关键词 machine learning optoelectronic deviceshoweverasblack optical field distributionwhich symbolic regression symbolic regression sr technique Fabry Perot laser discovering explicit symbolic relationship optical field distribution
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Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles 被引量:1
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作者 Yanting Liu Wei Huang +8 位作者 Jiayi Wen Xin Xiong Ting Xu Qi Wang Xiusheng Chen Xianxian Zhao Shihua Li Xiaojiang Li Weili Yang 《Neural Regeneration Research》 SCIE CAS 2025年第4期1124-1134,共11页
The vast majority of in vitro studies have demonstrated that PINK1 phosphorylates Parkin to work together in mitophagy to protect against neuronal degeneration.However,it remains largely unclear how PINK1 and Parkin a... The vast majority of in vitro studies have demonstrated that PINK1 phosphorylates Parkin to work together in mitophagy to protect against neuronal degeneration.However,it remains largely unclear how PINK1 and Parkin are expressed in mammalian brains.This has been difficult to address because of the intrinsically low levels of PINK1 and undetectable levels of phosphorylated Parkin in small animals.Understanding this issue is critical for elucidating the in vivo roles of PINK1 and Parkin.Recently,we showed that the PINK1 kinase is selectively expressed as a truncated form(PINK1–55)in the primate brain.In the present study,we used multiple antibodies,including our recently developed monoclonal anti-PINK1,to validate the selective expression of PINK1 in the primate brain.We found that PINK1 was stably expressed in the monkey brain at postnatal and adulthood stages,which is consistent with the findings that depleting PINK1 can cause neuronal loss in developing and adult monkey brains.PINK1 was enriched in the membrane-bound fractionations,whereas Parkin was soluble with a distinguishable distribution.Immunofluorescent double staining experiments showed that PINK1 and Parkin did not colocalize under physiological conditions in cultured monkey astrocytes,though they did colocalize on mitochondria when the cells were exposed to mitochondrial stress.These findings suggest that PINK1 and Parkin may have distinct roles beyond their well-known function in mitophagy during mitochondrial damage. 展开更多
关键词 NEURODEGENERATION PARKIN Parkinson’s disease PINK1 subcellular distribution
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Data driven prediction of fragment velocity distribution under explosive loading conditions 被引量:2
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作者 Donghwan Noh Piemaan Fazily +4 位作者 Songwon Seo Jaekun Lee Seungjae Seo Hoon Huh Jeong Whan Yoon 《Defence Technology(防务技术)》 2025年第1期109-119,共11页
This study presents a machine learning-based method for predicting fragment velocity distribution in warhead fragmentation under explosive loading condition.The fragment resultant velocities are correlated with key de... This study presents a machine learning-based method for predicting fragment velocity distribution in warhead fragmentation under explosive loading condition.The fragment resultant velocities are correlated with key design parameters including casing dimensions and detonation positions.The paper details the finite element analysis for fragmentation,the characterizations of the dynamic hardening and fracture models,the generation of comprehensive datasets,and the training of the ANN model.The results show the influence of casing dimensions on fragment velocity distributions,with the tendencies indicating increased resultant velocity with reduced thickness,increased length and diameter.The model's predictive capability is demonstrated through the accurate predictions for both training and testing datasets,showing its potential for the real-time prediction of fragmentation performance. 展开更多
关键词 Data driven prediction Dynamic fracture model Dynamic hardening model FRAGMENTATION Fragment velocity distribution High strain rate Machine learning
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A Trusted Distributed Oracle Scheme Based on Share Recovery Threshold Signature 被引量:1
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作者 Shihao Wang Xuehui Du +4 位作者 Xiangyu Wu Qiantao Yang Wenjuan Wang Yu Cao Aodi Liu 《Computers, Materials & Continua》 2025年第2期3355-3379,共25页
With the increasing popularity of blockchain applications, the security of data sources on the blockchain is gradually receiving attention. Providing reliable data for the blockchain safely and efficiently has become ... With the increasing popularity of blockchain applications, the security of data sources on the blockchain is gradually receiving attention. Providing reliable data for the blockchain safely and efficiently has become a research hotspot, and the security of the oracle responsible for providing reliable data has attracted much attention. The most widely used centralized oracles in blockchain, such as Provable and Town Crier, all rely on a single oracle to obtain data, which suffers from a single point of failure and limits the large-scale development of blockchain. To this end, the distributed oracle scheme is put forward, but the existing distributed oracle schemes such as Chainlink and Augur generally have low execution efficiency and high communication overhead, which leads to their poor applicability. To solve the above problems, this paper proposes a trusted distributed oracle scheme based on a share recovery threshold signature. First, a data verification method of distributed oracles is designed based on threshold signature. By aggregating the signatures of oracles, data from different data sources can be mutually verified, leading to a more efficient data verification and aggregation process. Then, a credibility-based cluster head election algorithm is designed, which reduces the communication overhead by clarifying the function distribution and building a hierarchical structure. Considering the good performance of the BLS threshold signature in large-scale applications, this paper combines it with distributed oracle technology and proposes a BLS threshold signature algorithm that supports share recovery in distributed oracles. The share recovery mechanism enables the proposed scheme to solve the key loss issue, and the setting of the threshold value enables the proposed scheme to complete signature aggregation with only a threshold number of oracles, making the scheme more robust. Finally, experimental results indicate that, by using the threshold signature technology and the cluster head election algorithm, our scheme effectively improves the execution efficiency of oracles and solves the problem of a single point of failure, leading to higher scalability and robustness. 展开更多
关键词 Blockchain threshold signature distributed oracle data submission share recovery
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Cement-mortar lining failure and metal release caused by electrochemical corrosion of ductile iron pipes in drinking water distribution systems 被引量:1
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作者 Hao Guo Rui Wang +5 位作者 Menghan Jiang Yimei Tian Yapeng Jin Weigao Zhao Chenwan Wang Jianhua Yin 《Journal of Environmental Sciences》 2025年第6期488-502,共15页
The electrochemical corrosion of ductile pipes(DPs)in drinking water distribution systems(DWDS)has a crucial impact on cement-mortar lining(CML)failure and metal release,potentially leading to drinking water quality d... The electrochemical corrosion of ductile pipes(DPs)in drinking water distribution systems(DWDS)has a crucial impact on cement-mortar lining(CML)failure and metal release,potentially leading to drinking water quality deterioration and posing a risk to public health.An in-situ scanning vibrating electrode technique(SVET)with micron-scale resolution,microscopic scale detection and water quality analysis were used to investigate the corrosion behavior and metal release from DPs throughout the whole CML failure process.Metal pollutants release occurred at three different stages of CML failure process,and there are potential risks of water quality deterioration exceeding the maximum allowable levels set by national standards in the partial failure stage and lining peeling stage.Furthermore,the effects of water chemistry(Cl^(−),SO_(4)^(2−),NO_(3)−,and Ca^(2+))on corrosion scale growth and iron release activity,were investigated during the CML partial failure stage.Results showed that the CML failure process in DPs was accelerated by the autocatalysis of localized corrosion.Cl^(−)was found to damage the uncorroded metal surface,while SO_(4)^(2−)mainly dissolved the corrosion scale surface,increasing iron release.Both the oxidation of NO_(3)−and selective sedimentation of Ca2+were found to enhance the stability of corrosion scales and inhibit iron release. 展开更多
关键词 Water distribution system Cement mortar lining Corrosion Metal release SVET
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