Cerebral vascular disease(CVD)also called thecerebral stroke or windstroke.There are twocommon types in clinic,that is,thrombotic CVDand hemorrhagic CVD.CVD has both a high incidence rate and a high mor-tality rate.It...Cerebral vascular disease(CVD)also called thecerebral stroke or windstroke.There are twocommon types in clinic,that is,thrombotic CVDand hemorrhagic CVD.CVD has both a high incidence rate and a high mor-tality rate.It has become展开更多
Colorectal cancer(CRC)is one of the most prevalent malignancies in Western countries and is among the leading causes of cancer-related mortality.Despite advancements in primary tumor resection and systemic therapies,a...Colorectal cancer(CRC)is one of the most prevalent malignancies in Western countries and is among the leading causes of cancer-related mortality.Despite advancements in primary tumor resection and systemic therapies,a significantproportion of patients develop metastatic disease,with the lungs being a frequent site of dissemination.1 Approximately 10%–25%of CRC patients experience pulmonary metastases,a condition that poses substantial challenges in oncological management.展开更多
Aortic stenosis(AS)is the most common valvular heart disease,with a prevalence of over 4%among octogenarians.[1]The prevalence of autopsy-confirmed wild-type transthyretin cardiac amyloidosis(ATTRwt-CA)increases with ...Aortic stenosis(AS)is the most common valvular heart disease,with a prevalence of over 4%among octogenarians.[1]The prevalence of autopsy-confirmed wild-type transthyretin cardiac amyloidosis(ATTRwt-CA)increases with age,accounting for 25%of patients aged 85 years and older in Europe and 12%of patients older than 80 years in Japan.[2,3]Recent studies have reported that ATTRwt-CA coexists in 11%-16%of older patients with AS undergoing transcatheter aortic valve replacement(TAVR).[1,4,5]In a metaanalysis by Ho et al.,[6]the prevalence rates of cardiac amyloidosis,predominantly ATTRwt-CA,in patients with AS and those referred for TAVR or surgical aortic valve replacement(SAVR)were 14.4%and 15.2%,respectively.Conversely,the prevalence of AS in patients with cardiac amyloidosis is 8.7%.Owing to the high surgical risk in patients with both AS and ATTRwt-CA,TAVR may be preferred over SAVR.展开更多
文摘Cerebral vascular disease(CVD)also called thecerebral stroke or windstroke.There are twocommon types in clinic,that is,thrombotic CVDand hemorrhagic CVD.CVD has both a high incidence rate and a high mor-tality rate.It has become
文摘Colorectal cancer(CRC)is one of the most prevalent malignancies in Western countries and is among the leading causes of cancer-related mortality.Despite advancements in primary tumor resection and systemic therapies,a significantproportion of patients develop metastatic disease,with the lungs being a frequent site of dissemination.1 Approximately 10%–25%of CRC patients experience pulmonary metastases,a condition that poses substantial challenges in oncological management.
文摘Aortic stenosis(AS)is the most common valvular heart disease,with a prevalence of over 4%among octogenarians.[1]The prevalence of autopsy-confirmed wild-type transthyretin cardiac amyloidosis(ATTRwt-CA)increases with age,accounting for 25%of patients aged 85 years and older in Europe and 12%of patients older than 80 years in Japan.[2,3]Recent studies have reported that ATTRwt-CA coexists in 11%-16%of older patients with AS undergoing transcatheter aortic valve replacement(TAVR).[1,4,5]In a metaanalysis by Ho et al.,[6]the prevalence rates of cardiac amyloidosis,predominantly ATTRwt-CA,in patients with AS and those referred for TAVR or surgical aortic valve replacement(SAVR)were 14.4%and 15.2%,respectively.Conversely,the prevalence of AS in patients with cardiac amyloidosis is 8.7%.Owing to the high surgical risk in patients with both AS and ATTRwt-CA,TAVR may be preferred over SAVR.
