1.New breakthroughs in cross-organ“brain-gut”strategies for the prevention and treatment of digestive diseases Refractory digestive diseases,represented by functional gastro-intestinal disorders and inflammation-to-...1.New breakthroughs in cross-organ“brain-gut”strategies for the prevention and treatment of digestive diseases Refractory digestive diseases,represented by functional gastro-intestinal disorders and inflammation-to-cancer transformation in the digestive tract,are associated with high incidence,com-plex pathogenesis,and considerable treatment challenges.These conditions are closely linked to acute and chronic stress-related injuries in the central nervous system.Single-modality therapies are insufficient to address the cross-organ nature of these dis-orders.Prof.Wei Wei(Wangjing Hospital,China Academy of Chinese Medical Sciences),Researcher Rong Peijing(Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences),and Prof.Liu Fengbin(The First Affiliated Hospital of Guangzhou University of Chinese Medicine)pro-posed a novel strategy of“brain-gut coordination.”A mul-ticenter randomized controlled trial involving 1796 patients with functional gastrointestinal disorders demonstrated that this strategy significantly improved symptoms such as abdom-inal bloating,abdominal pain,and diarrhea,as well as anxiety and depression.展开更多
基金the Project of Map of Scientific and Technological Talents in the Field of Traditional Chinese Medicine (XMSB20240923106)。
文摘1.New breakthroughs in cross-organ“brain-gut”strategies for the prevention and treatment of digestive diseases Refractory digestive diseases,represented by functional gastro-intestinal disorders and inflammation-to-cancer transformation in the digestive tract,are associated with high incidence,com-plex pathogenesis,and considerable treatment challenges.These conditions are closely linked to acute and chronic stress-related injuries in the central nervous system.Single-modality therapies are insufficient to address the cross-organ nature of these dis-orders.Prof.Wei Wei(Wangjing Hospital,China Academy of Chinese Medical Sciences),Researcher Rong Peijing(Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences),and Prof.Liu Fengbin(The First Affiliated Hospital of Guangzhou University of Chinese Medicine)pro-posed a novel strategy of“brain-gut coordination.”A mul-ticenter randomized controlled trial involving 1796 patients with functional gastrointestinal disorders demonstrated that this strategy significantly improved symptoms such as abdom-inal bloating,abdominal pain,and diarrhea,as well as anxiety and depression.