Natural products(NPs)derived from plants,microbes,and marine organisms have historically been a cornerstone of pharmacotherapy,accounting for approximately 35%of FDA-approved small-molecule drugs since 19811.These com...Natural products(NPs)derived from plants,microbes,and marine organisms have historically been a cornerstone of pharmacotherapy,accounting for approximately 35%of FDA-approved small-molecule drugs since 19811.These compounds have been instrumental in drug discovery,particularly for cancer and infectious diseases,as well as in other therapeutic areas such as cardiovascular diseases(e.g.,statins)and multiple sclerosis(e.g.,fingolimod).展开更多
文摘Natural products(NPs)derived from plants,microbes,and marine organisms have historically been a cornerstone of pharmacotherapy,accounting for approximately 35%of FDA-approved small-molecule drugs since 19811.These compounds have been instrumental in drug discovery,particularly for cancer and infectious diseases,as well as in other therapeutic areas such as cardiovascular diseases(e.g.,statins)and multiple sclerosis(e.g.,fingolimod).
