Congenital musculoskeletal and limb deformities(CMLD)seriously affect the physical and mental health of patients,and pose great challenges to healthcare systems worldwide.We explored the specific situation and changes...Congenital musculoskeletal and limb deformities(CMLD)seriously affect the physical and mental health of patients,and pose great challenges to healthcare systems worldwide.We explored the specific situation and changes of incidence,prevalence,disability-adjusted life years rates,and mortality of CMLD in under-5 children from 1990 to 2021 in different groups,including different regions,periods,genders and sociodemographic indices(SDI),through corresponding analytical models.Overall,the global disease burden of CMLD in under-5 children has decreased from 1990 to 2021.The disease burden of CMLD in under-5 children varied significantly among different regions and countries,and there was a strong correlation between the corresponding burden of disease and the level of SDI.In addition,cross-country inequality analysis showed that while absolute inequalities in the disease burden of CMLD in under-5 children have improved,relative inequalities have worsened.It is essential to reduce the global health impact of CMLD by implementing targeted interventions to improve health care in underdeveloped areas.展开更多
基金supported by the Scientific Research Projects of Colleges and Universities in Gansu Province(No.2023CYZC-03).
文摘Congenital musculoskeletal and limb deformities(CMLD)seriously affect the physical and mental health of patients,and pose great challenges to healthcare systems worldwide.We explored the specific situation and changes of incidence,prevalence,disability-adjusted life years rates,and mortality of CMLD in under-5 children from 1990 to 2021 in different groups,including different regions,periods,genders and sociodemographic indices(SDI),through corresponding analytical models.Overall,the global disease burden of CMLD in under-5 children has decreased from 1990 to 2021.The disease burden of CMLD in under-5 children varied significantly among different regions and countries,and there was a strong correlation between the corresponding burden of disease and the level of SDI.In addition,cross-country inequality analysis showed that while absolute inequalities in the disease burden of CMLD in under-5 children have improved,relative inequalities have worsened.It is essential to reduce the global health impact of CMLD by implementing targeted interventions to improve health care in underdeveloped areas.
