Age related macular degeneration (AMD) is a complex progres- sive neurodegenerative disease causing blindness in 30-35 million people worldwide. It affects the macula region of the retina leading to severe vision lo...Age related macular degeneration (AMD) is a complex progres- sive neurodegenerative disease causing blindness in 30-35 million people worldwide. It affects the macula region of the retina leading to severe vision loss and legal blindness in individuals 〉 50 years of age (Wong et al., 2014). The precise aetiology of AMD is unknown but smoking, age and genetic factors are major risk factors for AMD predisposition (Ding et al., 2009). The genetic basis of AMD is well described with a recent study from the International AMD gene consortium (IAMDGC) reporting 52 genetic variants across 34 loci associated with the risk of AMD pathogenesis and explaining more than 50% of the genetic heritabilitv of the disease (Fritsche et al., 2016).展开更多
In this comprehensive and well-structured review,Ragheb~([1])delves into the rising interest in intracavernosal platelet-rich plasma(PRP)therapy for erectile dysfunction(ED),an area where clinical curiosity has outpac...In this comprehensive and well-structured review,Ragheb~([1])delves into the rising interest in intracavernosal platelet-rich plasma(PRP)therapy for erectile dysfunction(ED),an area where clinical curiosity has outpaced standardization.With increasing attention on regenerative urology,this article provides a timely overview of both preclinical and clinical data surrounding PRP as a novel,autologous,and biologically intuitive treatment strategy for ED.展开更多
The purpose of the present study was to describe and provide insight on Detroit’s music industry,with the practical goal to inform the current state of music in Detroit and draw conclusive suggestions for bringing mu...The purpose of the present study was to describe and provide insight on Detroit’s music industry,with the practical goal to inform the current state of music in Detroit and draw conclusive suggestions for bringing music back to a forefront of Detroit.The study drew on a sample of convenience(N=4)by researcher networking and past work in the Detroit music industry.Eight themes were identified in a content analysis of interview responses.The study revealed a deep and common vision shared among diverse industry professionals-to bring national recognition back to Detroit.Everyone wants Detroit’s music industry to make a comeback,however,they realize it is a slow process to achieve that goal.展开更多
Electroencephalogram(EEG)is one of the most important bioelectrical signals related to brain activity and plays a crucial role in clinical medicine.Driven by continuously expanding applications,the development of EEG ...Electroencephalogram(EEG)is one of the most important bioelectrical signals related to brain activity and plays a crucial role in clinical medicine.Driven by continuously expanding applications,the development of EEG materials and technology has attracted considerable attention.However,systematic analysis of the sustainable development of EEG materials and technology is still lacking.This review discusses the sustainable development of EEG materials and technology.First,the developing course of EEG is introduced to reveal its significance,particularly in clinical medicine.Then,the sustainability of the EEG materials and technology is discussed from two main aspects:integrated systems and EEG electrodes.For integrated systems,sustainability has been focused on the developing trend toward mobile EEG systems and big-data monitoring/analyzing of EEG signals.Sustainability is related to miniaturized,wireless,portable,and wearable systems that are integrated with big-data modeling techniques.For EEG electrodes and materials,sustainability has been comprehensively analyzed from three perspectives:performance of different material/structural categories,sustainablematerials for EEGelectrodes,and sustainable manufacturing technologies.In addition,sustainable applications of EEG have been presented.Finally,the sustainable development of EEG materials and technology in recent decades is summarized,revealing future possible research directions as well as urgent challenges.展开更多
基金funding from the National Health and Medical Research Council of Australia (NHMRC) project grant 1008979Senior Research Fellowship 1028444 (PNB)+1 种基金Melbourne International research ScholarshipMelbourne International fee remission scholarship from the University of Melbourne Australia
文摘Age related macular degeneration (AMD) is a complex progres- sive neurodegenerative disease causing blindness in 30-35 million people worldwide. It affects the macula region of the retina leading to severe vision loss and legal blindness in individuals 〉 50 years of age (Wong et al., 2014). The precise aetiology of AMD is unknown but smoking, age and genetic factors are major risk factors for AMD predisposition (Ding et al., 2009). The genetic basis of AMD is well described with a recent study from the International AMD gene consortium (IAMDGC) reporting 52 genetic variants across 34 loci associated with the risk of AMD pathogenesis and explaining more than 50% of the genetic heritabilitv of the disease (Fritsche et al., 2016).
文摘In this comprehensive and well-structured review,Ragheb~([1])delves into the rising interest in intracavernosal platelet-rich plasma(PRP)therapy for erectile dysfunction(ED),an area where clinical curiosity has outpaced standardization.With increasing attention on regenerative urology,this article provides a timely overview of both preclinical and clinical data surrounding PRP as a novel,autologous,and biologically intuitive treatment strategy for ED.
文摘The purpose of the present study was to describe and provide insight on Detroit’s music industry,with the practical goal to inform the current state of music in Detroit and draw conclusive suggestions for bringing music back to a forefront of Detroit.The study drew on a sample of convenience(N=4)by researcher networking and past work in the Detroit music industry.Eight themes were identified in a content analysis of interview responses.The study revealed a deep and common vision shared among diverse industry professionals-to bring national recognition back to Detroit.Everyone wants Detroit’s music industry to make a comeback,however,they realize it is a slow process to achieve that goal.
基金National Natural Science Foundation of China,Grant/Award Number:62271458Sichuan Province Central Government Guides Local Science and Technology Development Project,Grant/Award Number:2023ZYD0015。
文摘Electroencephalogram(EEG)is one of the most important bioelectrical signals related to brain activity and plays a crucial role in clinical medicine.Driven by continuously expanding applications,the development of EEG materials and technology has attracted considerable attention.However,systematic analysis of the sustainable development of EEG materials and technology is still lacking.This review discusses the sustainable development of EEG materials and technology.First,the developing course of EEG is introduced to reveal its significance,particularly in clinical medicine.Then,the sustainability of the EEG materials and technology is discussed from two main aspects:integrated systems and EEG electrodes.For integrated systems,sustainability has been focused on the developing trend toward mobile EEG systems and big-data monitoring/analyzing of EEG signals.Sustainability is related to miniaturized,wireless,portable,and wearable systems that are integrated with big-data modeling techniques.For EEG electrodes and materials,sustainability has been comprehensively analyzed from three perspectives:performance of different material/structural categories,sustainablematerials for EEGelectrodes,and sustainable manufacturing technologies.In addition,sustainable applications of EEG have been presented.Finally,the sustainable development of EEG materials and technology in recent decades is summarized,revealing future possible research directions as well as urgent challenges.