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Single-Cell and Multi-Dimensional Data Analysis of the Key Role of IDH2 in Cervical Squamous Cell Carcinoma Progression
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作者 Xiaojuan Liu Zhenpeng Zhu +5 位作者 Chenyang Hou Hui Ma Xiaoyan Li Chunxing Ma Lisha Shu Huiying Zhang 《Biomedical and Environmental Sciences》 2025年第6期773-778,共6页
Cervical cancer,a leading malignancy globally,poses a significant threat to women's health,with an estimated 604,000 new cases and 342,000 deaths reported in 2020^([1]).As cervical cancer is closely linked to huma... Cervical cancer,a leading malignancy globally,poses a significant threat to women's health,with an estimated 604,000 new cases and 342,000 deaths reported in 2020^([1]).As cervical cancer is closely linked to human papilloma virus(HPV)infection,early detection relies on HPV screening;however,late-stage prognosis remains poor,underscoring the need for novel diagnostic and therapeutic targets^([2]). 展开更多
关键词 cervical squamous cell carcinoma IDH cervical cancera multi dimensional data analysis novel diagnostic therapeutic targets cervical cancer prognosis human papilloma virus hpv infectionearly
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Three Dimensional Kinematics Analysis of the Independent Suspension Multibody System 被引量:2
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作者 陈欣 林逸 +1 位作者 孙大刚 白文辉 《Journal of Beijing Institute of Technology》 EI CAS 1997年第4期80-86,共7页
Based on the theory of multibody system dynamics, the spatial kinematics analysis of the Mcpherson independent suspension widely used in the car was carried out. A practical and simpler method was provided to reduce t... Based on the theory of multibody system dynamics, the spatial kinematics analysis of the Mcpherson independent suspension widely used in the car was carried out. A practical and simpler method was provided to reduce the number of the generalized coordinates and constraint functions. By solving the nonlinear equations, the motion of any points in the whole suspension and wheel system can be predicted, including the spatial changes of the wheel alignment parameters which are of great importance to the car performances. 展开更多
关键词 independent suspension three dimension kinematic analysis multibody system
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Quantifying the Euphrates Electric Conductivity Depending on Parameters by Dimensional Analysis Method
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作者 Ali Hassan Hommadi Nadhir Al-Ansari 《Engineering(科研)》 CAS 2023年第5期301-317,共17页
The searching about methods to connect the variables with each other to reach equations including multi variables. The dimensional analysis is a method to facilitate the solution of difficult mathematic equations and ... The searching about methods to connect the variables with each other to reach equations including multi variables. The dimensional analysis is a method to facilitate the solution of difficult mathematic equations and experimental formulas;therefore methods of simplifying the difficult equations and obtaining a new equation with different variables is needed. In this study will use 2 methods (statically with dimensionally analysis) to obtain electric conductivity of water of Euphrates river by multi parameters that are time (t), temperature (Te), density, viscosity, discharge and water depth in upstream of Alhindya barrage which located in Babylon governorate, Iraq during winter 2019. The equations were obtained for EC with Te and t by data were collected from Alhindya barrage office with R<sup>2</sup> = 0.999 and R<sup>2</sup> = 0.995 by statically ways. Dimension analysis was utilized via 2 stages. In first stage was obtained on equation of EC with respect to Te, water density (ρ) and dynamic viscosity (μ) with constant time, depth of water and discharge and we obtain on R<sup>2</sup> was 0.994 and R<sup>2</sup> = 0.986. In second stage was obtained formula of EC with respect to Te, water density (ρ), dynamic viscosity (μ), with variable time, depth of water and discharge with we obtain on R<sup>2</sup> = 0.945 and R<sup>2</sup> = 0.94. The result of research indicates that applying the dimension analysis to connect more than one variable with each other to find best solutions and best methods to facilitate the solving the equations. From dimension analysis gave a clear visualization of the association of several variables to give a result that helps measure the electrical conductivity of water in the absence of a water test device. 展开更多
关键词 Electric Conductivity TEMPERATURE dimension analysis Statistical analysis
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Parametric Dimensional Analysis on the Structural Response of An Innovative Subsurface Tension Leg Platform in Ultra-Deep Water 被引量:4
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作者 ZHEN Xing-wei WU Jia-hao +2 位作者 HUANG Yi HAN Yue YAO Jin-jiang 《China Ocean Engineering》 SCIE EI CSCD 2018年第4期482-489,共8页
The innovative Subsurface Tension Leg Platform(STLP), which is designed to be located below Mean Water Level(M.W.L) to minimize direct wave loading and mitigate the effect of strong surface currents, is considered as ... The innovative Subsurface Tension Leg Platform(STLP), which is designed to be located below Mean Water Level(M.W.L) to minimize direct wave loading and mitigate the effect of strong surface currents, is considered as a competitive alternative system to support shallow-water rated well completion equipment and rigid risers for large ultra-deep water oil field development. A detailed description of the design philosophy of STLP has been published in the series of papers and patents. Nonetheless, design uncertainties arise as limited understanding of various parameters effects on the structural response of STLP, pertaining to the environmental loading, structural properties and hydrodynamic characteristics. This paper focuses on providing quantitative methodology on how each parameter affects the structural response of STLP, which will facilitate establishing the unique design criteria as regards to STLP. Firstly, the entire list of dimensionless groups of input and output parameters is proposed based on VaschyBuckingham theory. Then, numerical models are built and a series of numerical tests are carried out for validating the obtained dimensionless groups. On this basis, the calculation results of a great quantity of parametric studies on the structural response of STLP are presented and discussed in detail. Further, empirical formulae for predicting STLP response are derived through nonlinear regression analysis. Finally, conclusions and discussions are made. It has been demonstrated that the study provides a methodology for better control of key parameters and lays the foundation for optimal design of STLP. The obtained conclusions also have wide ranging applicability in reference to the engineering design and design analysis aspects of deepwater buoy supporting installations, such as Grouped SLOR or TLR system. 展开更多
关键词 subsurface tension leg platform structural response dimensional analysis ultra-deep water
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Dimensional analysis of earthquake-induced pounding between adjacent inelastic MDOF buildings 被引量:4
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作者 Zhai Changhai Jiang Shan +1 位作者 Li Shuang Xie Lili 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2015年第2期295-313,共19页
In this study the seismic pounding response of adjacent multi-degree-of-freedom(MDOF) buildings with bilinear inter-story resistance characteristics is investigated through dimensional analysis. The application of dim... In this study the seismic pounding response of adjacent multi-degree-of-freedom(MDOF) buildings with bilinear inter-story resistance characteristics is investigated through dimensional analysis. The application of dimensional analysis leads to a condensed presentation of the response, and the remarkable self-similarity property for bilinear MDOF buildings with inelastic collision is uncovered. It is shown that when the response is expressed in the appropriate dimensionless form, response spectra for any intensity of the excitation collapse to a single master curve. The reduced Π set explicitly describes the interaction between the colliding structures. The effect of pounding on the MDOF building’s response is illustrated using three well-divided spectral regions(amplifi ed, de-amplifi ed and unaffected regions). Parametric studies are conducted to investigate the effects of the story stiffness of structures, the story stiffness ratio and mass ratio of adjacent buildings, the structural inelastic characteristics and the gap size values. Results show that(i) the infl uence of system stiffness ratio to the lighter and more fl exible building is more signifi cant in the fi rst spectral region, where the maximum response of the building is amplifi ed because of pounding; and(ii) the velocity and pounding force of the heavier and stiffer building is unexpectedly sensitive to the mass ratio of adjacent buildings. 展开更多
关键词 POUNDING dimensional analysis earthquake engineeri
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Dimensional analysis and extended hydrodynamic theory applied to long-rod penetration of ceramics 被引量:2
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作者 J.D.CLAYTON 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2016年第4期334-342,共9页
Principles of dimensional analysis are applied in a new interpretation of penetration of ceramic targets subjected to hypervelocity impact. The analysis results in a power series representation – in terms of inverse ... Principles of dimensional analysis are applied in a new interpretation of penetration of ceramic targets subjected to hypervelocity impact. The analysis results in a power series representation – in terms of inverse velocity – of normalized depth of penetration that reduces to the hydrodynamic solution at high impact velocities. Specifically considered are test data from four literature sources involving penetration of confined thick ceramic targets by tungsten long rod projectiles. The ceramics are AD-995 alumina, aluminum nitride, silicon carbide, and boron carbide.Test data can be accurately represented by the linear form of the power series, whereby the same value of a single fitting parameter applies remarkably well for all four ceramics. Comparison of the present model with others in the literature(e.g., Tate's theory) demonstrates a target resistance stress that depends on impact velocity, linearly in the limiting case. Comparison of the present analysis with recent research involving penetration of thin ceramic tiles at lower typical impact velocities confirms the importance of target properties related to fracture and shear strength at the Hugoniot Elastic Limit(HEL) only in the latter. In contrast, in the former(i.e., hypervelocity and thick target) experiments, the current analysis demonstrates dominant dependence of penetration depth only by target mass density. Such comparisons suggest transitions from microstructure-controlled to density-controlled penetration resistance with increasing impact velocity and ceramic target thickness.Production and hosting by Elsevier B.V. on behalf of China Ordnance Society. 展开更多
关键词 CERAMICS Terminal ballistics ARMOR dimensional analysis HYDRODYNAMICS
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Three dimensional finite element analysis of anatomic distal radius Nitinol memory connector treating distal radius fracture 被引量:4
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作者 苏佳灿 张春才 +8 位作者 禹宝庆 许硕贵 王家林 纪方 张雪松 吴建国 王保华 薛召军 丁祖泉 《Journal of Medical Colleges of PLA(China)》 CAS 2003年第4期226-229,共4页
Objective: To study the memory biomechanical character of anatomic distal radius Nitinol memory connector (DRMC) in treating distal radius fracture. Methods: Establishing three dimensional model and finite element ana... Objective: To study the memory biomechanical character of anatomic distal radius Nitinol memory connector (DRMC) in treating distal radius fracture. Methods: Establishing three dimensional model and finite element analysis, we calculated the stress in and around the fracture faces when distal radius fracture was fixated with DRMC. Results: Axial holding stress produced by holding part of DRMC on distal radius was 14.66 MPa. The maximum stress of holding part was 40-70 MPa, the minimum stress was 3-7 MPa,and the stress of compression part was 20-40 MPa. Conclusion: The distribution of stress produced by DRMC around the fracture line is reasonable, and axial holding stress can help stabilize fracture during earlier period. The existence of longitudal compression and memory effect can transfer fixated disused section into developed section and enhance fracture healing. 展开更多
关键词 distal radius Nitinol memory connector distal radius fracture 3 dimensional finite element analysis memory biomechanics
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Numerical and Dimensional Analysis for Prediction of Line Heating Residual Deformations 被引量:1
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作者 Pankaj Biswas Nisith Ranjan Mandal Om Prakash Sha 《Journal of Marine Science and Application》 2010年第1期14-21,共8页
Line heating process is a very complex phenomenon as a variety of factors affects the amount of residual deformations. Numerical thermal and mechanical analysis of line heating for prediction of residual deformation i... Line heating process is a very complex phenomenon as a variety of factors affects the amount of residual deformations. Numerical thermal and mechanical analysis of line heating for prediction of residual deformation is time consuming. In the present work dimensional analysis has been presented to obtain a new relationship between input parameters and resulting residual deformations during line heating process. The temperature distribution and residual deformations for 6 mm, 8 mm, 10 mm and 12 mm thick steel plates were numerically estimated and compared with experimental and published results. Extensive data generated through a validated FE model were used to find co-relationship between the input parameters and the resulting residual deformation by multiple regression analysis. The results obtained from the deformation equations developed in this work compared well with those of the FE analysis with a drop in the computation time in the order of 100 (computational time required for FE analysis is around 7 200 second to 9 000 seconds and where the time required for getting the residual deformation by developed equations is only 60 to 90 seconds). 展开更多
关键词 dimensional analysis 3-D finite element analysis elasto-plastic analysis residual deformations multiple regression analysis oxy-acetylene gas flame
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Material Equivalent Test Based on Dimensional Analysis for Fragment Penetrating Antenna Target 被引量:1
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作者 刘锋 石全 陈材 《Journal of Donghua University(English Edition)》 EI CAS 2016年第2期206-209,共4页
Phased array radar is the main sensor in a battlefield.Phased array antenna is the main execution unit of the phased array radar,and it greatly affects the reliability of the phased array radar. As a result,the fragme... Phased array radar is the main sensor in a battlefield.Phased array antenna is the main execution unit of the phased array radar,and it greatly affects the reliability of the phased array radar. As a result,the fragment damaged antenna test is important.As the materials of phased array antenna are not easy to get,the fragment damaged antenna test is difficult to carry out. Then we present a study on this problem and introduce the principles of dimensional analysis to solve it. Firstly, the fragments damage antenna target dimensionless model is constructed. Secondly,the finite element analysis software ANSYS / LS-DYNA are used to carry out a large number of different materials simulation test for dimensional analysis. Finally,based on dimensional test analysis,the materials equivalent empirical model between different antennas target is presented in the same damage. The results of this study provide a feasible and valuable solution for different materials' target damaged test. 展开更多
关键词 FRAGMENTS phased array antenna dimensional analysis material equivalent
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Three dimensional finite element analysis of acetabulum loaded by static stress and its biomechanical significance 被引量:1
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作者 苏佳灿 张本 +4 位作者 禹宝庆 张春才 陈学强 王保华 丁祖泉 《Journal of Medical Colleges of PLA(China)》 CAS 2005年第6期377-382,共6页
Objective:To explore the mechanical behavior of acetabulum loaded by static stress and provide the mechanical basis for clinical analysis and judgement on acetabular mechanical distribution and effect of static stress... Objective:To explore the mechanical behavior of acetabulum loaded by static stress and provide the mechanical basis for clinical analysis and judgement on acetabular mechanical distribution and effect of static stress.Methods:By means of computer simulation, acetabular three dimensional model was input into three dimensional finite element analysis software ANSYS7.0. The acetabular mechanical behavior was calculated and the main stress value, stress distribution and acetabular unit displacement in the direction of main stress were analyzed when anterior wall of acetabulum and acetabular crest were loaded by 1 000 N static stress. Results:When acetabular anterior wall loaded by X direction and Z direction composition force, the stress passed along 4 directions: (1)from acetabular anterior wall to pubic symphysis along superior branch of pubis firstly, (2)from acetabular anterior wall to cacroiliac joint along pelvic ring,(3)in the acetabulum,(4)from the suffered point to ischium. When acetabular crest loaded by X direction and Y direction composition force, the stress transmitted to 4 directions: (1)from acetabular crest to ilium firstly, (2)from suffered point to cacroiliac joint along pelvic ring,(3) in the acetabulum ,(4)along the pubic branch,but no stress transmitted to the ischium branch.Conclusion:Analyzing the stress distribution of acetabulum and units displacement when static stress loaded can provide internal fixation point for acetabular fracture treatment and help understand the stress distribution of acetabulum. 展开更多
关键词 ACETABULUM static stress stress analysis three dimensional finite element analysis
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Data-driven prediction of dimensionless quantities for semi-infinite target penetration by integrating machine-learning and feature selection methods 被引量:1
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作者 Qingqing Chen Xinyu Zhang +2 位作者 Zhiyong Wang Jie Zhang Zhihua Wang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第10期105-124,共20页
This study employs a data-driven methodology that embeds the principle of dimensional invariance into an artificial neural network to automatically identify dominant dimensionless quantities in the penetration of rod ... This study employs a data-driven methodology that embeds the principle of dimensional invariance into an artificial neural network to automatically identify dominant dimensionless quantities in the penetration of rod projectiles into semi-infinite metal targets from experimental measurements.The derived mathematical expressions of dimensionless quantities are simplified by the examination of the exponent matrix and coupling relationships between feature variables.As a physics-based dimension reduction methodology,this way reduces high-dimensional parameter spaces to descriptions involving only a few physically interpretable dimensionless quantities in penetrating cases.Then the relative importance of various dimensionless feature variables on the penetration efficiencies for four impacting conditions is evaluated through feature selection engineering.The results indicate that the selected critical dimensionless feature variables by this synergistic method,without referring to the complex theoretical equations and aiding in the detailed knowledge of penetration mechanics,are in accordance with those reported in the reference.Lastly,the determined dimensionless quantities can be efficiently applied to conduct semi-empirical analysis for the specific penetrating case,and the reliability of regression functions is validated. 展开更多
关键词 Data-driven dimensional analysis PENETRATION Semi-infinite metal target dimensionless numbers Feature selection
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Discriminated Dimensional Analysis Versus Classical Dimensional Analysis and Applications to Heat Transfer and Fluid Dynamics
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作者 F. Alhama C.N. Madrid 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2007年第5期626-631,共6页
In contrast to classical dimensional analysis, discriminated dimensional analysis assumes that spatial coordinates are dimensionally independent of each other and allows other types of geometrical quantity to be used ... In contrast to classical dimensional analysis, discriminated dimensional analysis assumes that spatial coordinates are dimensionally independent of each other and allows other types of geometrical quantity to be used in the dimensional basis, such as surfaces and angles. As a consequence, discriminated dimensional analysis leads to a lower number of dimensional groups, which makes the solution more precise. Besides, these discriminated groups have a clear physical meaning in terms of force and energy balances. The paper introduces this technique and provides dimensional equations for the main quantities and physical parameters of the heat transfer and fluid flow fields. Two applications are presented to demonstrate the efficiency of this method. 展开更多
关键词 discriminated dimensional analysis heat transfer fluid dynamics dimensionless number
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Quantifying.Associations among Dimensions of Ears and Their Form Factors in Maize(Zea Mays)Using Dimensional Analysis
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作者 Hongbo CAO Gaimei LIANG Jinzhong YANG 《Agricultural Science & Technology》 CAS 2016年第10期2287-2292,共6页
Ear morphological traits such as volume and shape are important features of maize and the quantitative associations among them can help understand kernel yield determination. 150 mature ears each of 4 maize cultivars ... Ear morphological traits such as volume and shape are important features of maize and the quantitative associations among them can help understand kernel yield determination. 150 mature ears each of 4 maize cultivars were collected from field experiments, and ear length(L), diameter(D), area(S) and volume(V) were recorded for individual ears, kernel weight per ear also recorded for a portion of the examined ears. Following principles of dimensional analysis, 8 theoretical equations of 3 sets,which relate ear higher dimensions to its length and diameter, were developed and parameterized and validated with the field observations. The 3 optimized equations showed that the shape of ears in maize can be featured with 3 dimensionless form factors, namely diameter-to-length ratio(c=D/L), areal form factor(b=S/L/D), and volumetric form factor(a=V/L/D/D). Statistically,all of them were significantly different among cultivars, and a's values varied from 0.582 to 0.612, and b's 0.839-0.868, and c's 0.242-0.308. Volumetric form factor and areal form factor could estimate precisely ear volume and area respectively, but diameter-to-length ratio was not suitable to estimate ear diameter by its length. Ear volume explained almost all variation of ear kernel weight and product L*D*D did the same substantially. Dimensional analysis proved to be promising in understanding relationship among morphological traits of ears in maize. Its application in crop researches should improve our knowledge of the physical properties of crop plants. 展开更多
关键词 Maize(Zea Mays) dimensional analysis Ear shape Volumetric form factors Ear volume Diameter-to-length ratio Ear kernel weight
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Dimensional analysis of the impact toughness test for synthetic diamond grits
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作者 杨慧 麦绿波 +4 位作者 卢灿华 仝毅 王志涛 张凤岭 黄风雷 《Journal of Beijing Institute of Technology》 EI CAS 2016年第1期1-6,共6页
The method,in which a few carats of diamond grits are placed inside a capsule together with a steel ball,shaken for a number of times,and the unbroken ratio of the grits is then used to evaluate the quality of the dia... The method,in which a few carats of diamond grits are placed inside a capsule together with a steel ball,shaken for a number of times,and the unbroken ratio of the grits is then used to evaluate the quality of the diamond,has been well established for many years.However,the unbroken percentage,in an equivalent view,represents the impact toughness of the grits and cannot reflect the value of the crushing energy.Most of the previous empirical formulas obtained from experiments by scholars cannot be applied to practical tests.In this paper,a dimensional analysis was applied to investigate the impact toughness experiment,and the dimensionless relationship has been built among those variables such as the toughness index,the impact time,the impact frequency and the crushing energy per unit area.According to the results of a large number of experiments with synthetic diamond grits of mesh size 45/50,the percentage of the broken grits H is proportional to the impact time T^(1.14) when the impact frequency is 2400 r/min,and the impact frequency f^(2.576) when the number of impacts is 2000. 展开更多
关键词 synthetic diamond toughness index dimensional analysis impact toughness test
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Influnce of three dimensional green biomass on Shanghai atmosphere enviroment by analysis with CIS technique
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《Global Geology》 1998年第1期101-101,共1页
关键词 CIS Influnce of three dimensional green biomass on Shanghai atmosphere enviroment by analysis with CIS technique
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Imbibition Front and Phase Distribution in Shale Based on Lattice Boltzmann Method 被引量:1
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作者 Li Lu Yadong Huang +2 位作者 Kuo Liu Xuhui Zhang Xiaobing Lu 《Computer Modeling in Engineering & Sciences》 2025年第2期2173-2190,共18页
To study the development of imbibition such as the imbibition front and phase distribution in shale,the Lattice Boltzmann Method(LBM)is used to study the imbibition processes in the pore-throat network of shale.Throug... To study the development of imbibition such as the imbibition front and phase distribution in shale,the Lattice Boltzmann Method(LBM)is used to study the imbibition processes in the pore-throat network of shale.Through dimensional analysis,four dimensionless parameters affecting the imbibition process were determined.A color gradient model of LBM was used in computation based on a real core pore size distribution.The numerical results show that the four factors have great effects on imbibition.The impact of each factor is not monotonous.The imbibition process is the comprehensive effect of all aspects.The imbibition front becomes more and more non-uniform with time in a heterogeneous pore-throat network.Some non-wetting phases(oil here)cannot be displaced out.The displacement efficiency and velocity do not change monotonously with any factor.The development of the average imbibition length with time is not smooth and not linear in a heterogeneous pore-throat network.Two fitting relations between the four dimensionless parameters and the imbibition velocity and efficiency are obtained,respectively. 展开更多
关键词 IMBIBITION LBM dimensional analysis SHALE
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Dimensional analysis unexpectedly indicates the world’s first petroleum discovery at depths exceeding 10 km
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作者 Shuheng Du Ya-Pu Zhao 《The Innovation》 2025年第8期3-4,共2页
For ages,scholars and engineers across the globe have been unceasing in their quest to unlock the mysteries of the 10,000-m-deep Earth,driven by the pursuit of new scientific theories and energy resources.On February ... For ages,scholars and engineers across the globe have been unceasing in their quest to unlock the mysteries of the 10,000-m-deep Earth,driven by the pursuit of new scientific theories and energy resources.On February 20,2025,China National Petroleum Corporation(CNPC)made a momentous announcement:China’s inaugural scientific exploration well at the 10,000-m level,the“Shenditake 1”well,nestled in the hinterland of the Taklimakan Desert in Xinjiang,was officially completed after reaching a staggering depth of 10,910 m beneath the surface. 展开更多
关键词 petroleum discovery depths exceeding km reaching staggering depth energy resources scientific theories dimensional analysis energy resourceson scientific exploration
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The damage of sequential explosions in reinforced concrete:Experimental and numerical investigation
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作者 Libin Wang Zhun Bai +3 位作者 Bingwen Qian Yutao Hu Liangquan Wang Gang Zhou 《Defence Technology(防务技术)》 2025年第6期284-297,共14页
The development of guidance technology has made it possible for the earth penetration weapons(EPWs)to impact the target repeatedly at a close range. To investigative the damage of single and sequential strike induced ... The development of guidance technology has made it possible for the earth penetration weapons(EPWs)to impact the target repeatedly at a close range. To investigative the damage of single and sequential strike induced by the EPWs, experimental and numerical investigations are carried out in this paper.Firstly, a series of sequential explosion tests are conducted to provide the basic data of the crater size.Then, a numerical model is established to simulate the damage effects of sequential explosions using the meshfree method of Smoothed particle Galerkin. The effectiveness of numerical model is verified by comparison with the experimental results. Finally, based on dimensional analysis, several empirical formulas for describing the crater size are presented, including the conical crater diameter and the conical crater depth of the single explosion, the conical crater area and the joint depth of the secondary explosion. The formula for the single explosion expresses the relationship between the aspect ratio of the charge ranging from 3 to 7, the dimensionless buried depth ranging from 2 to 14 and the crater size. The formula for the secondary explosion expresses the relationship between the relative position of the two explosions and the crater size. All of data can provide reference for the design of protective structures. 展开更多
关键词 CRATER dimensional analysis Reinforced concrete Buried depth Aspect ratio Smoothed particle Galerkin
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Modeling transport and bridging behavior of lost circulation materials in a hydraulic fracture
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作者 Shaoyi Cheng Bisheng Wu +3 位作者 Herbert E.Huppert Tianshou Ma Zhaowei Chen Peng Tan 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第5期2650-2664,共15页
Lost circulation of drilling fluid is one of the most common and costly problems in drilling operations.This highlights the importance of wellbore strengthening treatment sthat can utilize lost circulation materials(L... Lost circulation of drilling fluid is one of the most common and costly problems in drilling operations.This highlights the importance of wellbore strengthening treatment sthat can utilize lost circulation materials(LCMs)to seal fractures associated with the wellbore.In this work,a numerical model accounting for the deformation of surrounding rock,fluid flow in the fracture,fracture propagation,and the transport of LCMs is presented to investigate the wellbore strengthening,from the fracture initiation to the fracture arrest,due to plugs formed by LCMs.The equations governing the rock deformation and fluid flow are solved by the dual boundary element method and the finite volume method,respectively.The transport of LCMs is solved based on an empirical constitutive model in suspension flow,and several characteristic quantities are derived by dimensional analysis.It is found that two dimensionless parameters,dimensionless toughness and normalized initial particle concentration,control the migration of LCM particles.The numerical results show that the dimensionless toughness influences the entrance and bridging of LCMs while the initial concentration controls the location of the particle bridging.When the initial concentration is larger than 0.8,the particle bridging tends to occur near the fracture entry.Conversely,when the initial concentration is less than 0.8,the particle bridging occurs near the fracture tip.This work provides an effective tool to predict the LCM transport and plugging in the wellbore strengthening process. 展开更多
关键词 Wellbore strengthening Lost circulation materials(LCMs) Particle bridging Hydraulic fracture dimensional analysis Bridging location
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Energy instability mechanism of existing goaf roof under impact load
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作者 GU Jinze CHANG Yuan +5 位作者 REN Fuqiang ZOU Baoping ZHU Chun WU Fei ZHANG Xiaoyun CHEN Bingbing 《Journal of Mountain Science》 2025年第5期1734-1747,共14页
The stability and fracture behavior of a goaf roof beneath an open-pit bench are critical concerns,especially under impact loading.However,the effect of the thickness-to-span ratio on dynamic failure modes remains lar... The stability and fracture behavior of a goaf roof beneath an open-pit bench are critical concerns,especially under impact loading.However,the effect of the thickness-to-span ratio on dynamic failure modes remains largely unexplored,as existing research focuses mainly on static stability.Energy dissipation and instability evolution under impact loading require further study.To address this gap,this study conducts drop-weight impact experiments on specimens with circular perforations,complemented by numerical simulations.By integrating dimensional analysis,cusp catastrophe theory,and strength reduction techniques,the dynamic instability mechanism of goaf roofs with varying thickness-to-span ratios is revealed.Results show that the thickness-to-span ratio significantly influences energy accumulation and dissipation during roof failure.A higher ratio increases both the magnitude and rate of energy dissipation,particularly during crack initiation and stable propagation,while its impact diminishes in the final failure stage.Optimizing the thickness-to-span ratio within a critical range enhances structural stability,improving the safety factor by up to 83%.However,beyond a certain threshold,additional thickness yields diminishing benefits.This study provides new insights into the energy-based instability mechanism of goaf roofs under impact loads,establishing a theoretical foundation for early warning systems and optimized safety design. 展开更多
关键词 Drop weight impact Goaf roof Thickness-to-span ratio dimensional analysis Energy mutation
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