To the Editor:As a student actively involved in advocacy for heart disease prevention,I was particularly intrigued by the policymaking implications of digital interventions in the article "Digital components and ...To the Editor:As a student actively involved in advocacy for heart disease prevention,I was particularly intrigued by the policymaking implications of digital interventions in the article "Digital components and interaction types in counseling interventions for childhood and adolescent obesity:A systematic review" [1].Through my work as the Founder and President of the nonprofit Guardians of Heart,I have developed and promoted early educational programs,digital tools,and community outreach initiatives designed to instill heart-healthy habits in youth,intending to mitigate risk factors such as obesity that significantly contribute to cardiovascular disease later in life.展开更多
OBJECTIVE： To construct a protein-protein interaction（PPI） network in hypertension patients with blood-stasis syndrome（BSS） by using digital gene expression（DGE） sequencing and database mining techniques.METHOD...OBJECTIVE： To construct a protein-protein interaction（PPI） network in hypertension patients with blood-stasis syndrome（BSS） by using digital gene expression（DGE） sequencing and database mining techniques.METHODS： DGE analysis based on the Solexa Genome Analyzer platform was performed on vascular endothelial cells incubated with serum of hypertension patients with BSS. The differentially expressed genes were f iltered by comparing the expression levels between the different experimental groups. Then functional categories and e nriched pathways of the unique genes for BSS were analyzed using Database for Annotation, Visualization and Integrated Discovery（DAVID） to select those in the enrichment pathways. I nterologous Interaction Database（I2D） was used to construct PPI networks with the selected genes for hypertension patients with BSS. The potential candidate genes related to BSS were identif ied by comparing the number of relationships among genes. Confi rmed by quantitative reverse transcription-polymerase chain reaction（q RTPCR）, gene ontology（GO） analysis was used to infer the functional annotations of the potential candidate genes for BSS.RESULTS： With gene enrichment analysis using DAVID, a list of 58 genes was chosen from the unique genes. The selected 58 genes were analyzed using I2 D, and a PPI network was constructed. Based on the network analysis results, candidate genes for BSS were identifi ed：DDIT3, JUN, HSPA8, NFIL3, HSPA5, HIST2H2 BE, H3F3 B, CEBPB, SAT1 and GADD45 A. Verif ied through qRT-PCR and analyzed by GO, the functional annotations of the potential candidate genes were explored.CONCLUSION： Compared with previous methodologies reported in the literature, the present DGE analysis and data mining method have shown a great improvement in analyzing BSS.展开更多
Confucianism is one of the foundations of Chinese philosophy, which has a great influence on the character and temperament of the Chinese nation in the history of China, and plays an important role in the development ...Confucianism is one of the foundations of Chinese philosophy, which has a great influence on the character and temperament of the Chinese nation in the history of China, and plays an important role in the development of Chinese civilization. This paper discusses the influence of Confucianism on advertising. Advertising is an integral part of the social culture system, the advertising and advertising works and cultural characteristics of their dissemination of scientific and cultural knowledge, values and way of life, constitute a unique social and cultural landscape. We discuss the influence of Confucian traditional culture on Chinese advertising. Under the background of globalization, it is of great significance and guidance for the theoretical study of Chinese advertising and the real world to explore the influence of Confucian culture on Chinese advertising.展开更多
At the global themed event of 2025 Lanting Culture Salon:Chinese Calligraphy,we witnessed the inheritance and innovation of the art of calligraphy.Artists,based on the traditional calligraphy,incorporated new creativi...At the global themed event of 2025 Lanting Culture Salon:Chinese Calligraphy,we witnessed the inheritance and innovation of the art of calligraphy.Artists,based on the traditional calligraphy,incorporated new creativity and elements,having the art of calligraphy radiate new vitality and vigor.These activities broke through the traditional exhibition mode by adopting innovative forms such as digital interaction,cross-border creation and immersive experiences.This allowed the visitors to experience the charm of the art of calligraphy through interaction,further promoting communication and popularization of calligraphy culture.展开更多
In order to improve the parasites experimental teaching quality, Digital Microscope System is used to replace the ordinary optical microscope in the teaching of eggs, imagoes, and tissue slices. The new model of exper...In order to improve the parasites experimental teaching quality, Digital Microscope System is used to replace the ordinary optical microscope in the teaching of eggs, imagoes, and tissue slices. The new model of experimental teaching, integrating modem information technology into the parasite experimental teaching, gives full play to the students＇ learning enthusiasm, initiative and creativity and improves the quality of experimental teaching. And at the same time, it provides a basis for the microbiological and pathological experimental teaching reform.展开更多
In order to study the role of the new technological concept of shared experiences in the digital interactive experience of cultural heritage and apply it to the digital interactive experience of cultural heritage to s...In order to study the role of the new technological concept of shared experiences in the digital interactive experience of cultural heritage and apply it to the digital interactive experience of cultural heritage to solve the current problems in this field,starting from the mixed reality(MR) technology that the shared experiences rely on,proper software and hardware platforms were investigated and selected,a universal shared experiences solution was designed,and an experimental project based on the proposed solution was made to verify its feasibility.In the end,a proven and workable shared experiences solution was obtained.This solution included a proposed MR spatial alignment method,and it integrated the existing MR content production process and standard network synchronization functions.Furthermore,it is concluded that the introduction and reasonable use of new technologies can help the development of the digital interactive experience of cultural heritage.The shared experiences solution for the digital interactive experience of cultural heritage balances investment issues in the exhibition,display effect,and user experience.It can speed up the promotion of cultural heritage and bring the vitality of MR technology to relevant projects.展开更多
文摘To the Editor:As a student actively involved in advocacy for heart disease prevention,I was particularly intrigued by the policymaking implications of digital interventions in the article "Digital components and interaction types in counseling interventions for childhood and adolescent obesity:A systematic review" [1].Through my work as the Founder and President of the nonprofit Guardians of Heart,I have developed and promoted early educational programs,digital tools,and community outreach initiatives designed to instill heart-healthy habits in youth,intending to mitigate risk factors such as obesity that significantly contribute to cardiovascular disease later in life.
基金supported by the National Natural Science Foundation of China (No. 81173157)the Guangdong Natural Science Foundation (No. 10151063201000045)
文摘OBJECTIVE： To construct a protein-protein interaction（PPI） network in hypertension patients with blood-stasis syndrome（BSS） by using digital gene expression（DGE） sequencing and database mining techniques.METHODS： DGE analysis based on the Solexa Genome Analyzer platform was performed on vascular endothelial cells incubated with serum of hypertension patients with BSS. The differentially expressed genes were f iltered by comparing the expression levels between the different experimental groups. Then functional categories and e nriched pathways of the unique genes for BSS were analyzed using Database for Annotation, Visualization and Integrated Discovery（DAVID） to select those in the enrichment pathways. I nterologous Interaction Database（I2D） was used to construct PPI networks with the selected genes for hypertension patients with BSS. The potential candidate genes related to BSS were identif ied by comparing the number of relationships among genes. Confi rmed by quantitative reverse transcription-polymerase chain reaction（q RTPCR）, gene ontology（GO） analysis was used to infer the functional annotations of the potential candidate genes for BSS.RESULTS： With gene enrichment analysis using DAVID, a list of 58 genes was chosen from the unique genes. The selected 58 genes were analyzed using I2 D, and a PPI network was constructed. Based on the network analysis results, candidate genes for BSS were identifi ed：DDIT3, JUN, HSPA8, NFIL3, HSPA5, HIST2H2 BE, H3F3 B, CEBPB, SAT1 and GADD45 A. Verif ied through qRT-PCR and analyzed by GO, the functional annotations of the potential candidate genes were explored.CONCLUSION： Compared with previous methodologies reported in the literature, the present DGE analysis and data mining method have shown a great improvement in analyzing BSS.
文摘Confucianism is one of the foundations of Chinese philosophy, which has a great influence on the character and temperament of the Chinese nation in the history of China, and plays an important role in the development of Chinese civilization. This paper discusses the influence of Confucianism on advertising. Advertising is an integral part of the social culture system, the advertising and advertising works and cultural characteristics of their dissemination of scientific and cultural knowledge, values and way of life, constitute a unique social and cultural landscape. We discuss the influence of Confucian traditional culture on Chinese advertising. Under the background of globalization, it is of great significance and guidance for the theoretical study of Chinese advertising and the real world to explore the influence of Confucian culture on Chinese advertising.
文摘At the global themed event of 2025 Lanting Culture Salon:Chinese Calligraphy,we witnessed the inheritance and innovation of the art of calligraphy.Artists,based on the traditional calligraphy,incorporated new creativity and elements,having the art of calligraphy radiate new vitality and vigor.These activities broke through the traditional exhibition mode by adopting innovative forms such as digital interaction,cross-border creation and immersive experiences.This allowed the visitors to experience the charm of the art of calligraphy through interaction,further promoting communication and popularization of calligraphy culture.
文摘In order to improve the parasites experimental teaching quality, Digital Microscope System is used to replace the ordinary optical microscope in the teaching of eggs, imagoes, and tissue slices. The new model of experimental teaching, integrating modem information technology into the parasite experimental teaching, gives full play to the students＇ learning enthusiasm, initiative and creativity and improves the quality of experimental teaching. And at the same time, it provides a basis for the microbiological and pathological experimental teaching reform.
基金supported by the National Key Research and Development Program of China (2020YFF0305304)。
文摘In order to study the role of the new technological concept of shared experiences in the digital interactive experience of cultural heritage and apply it to the digital interactive experience of cultural heritage to solve the current problems in this field,starting from the mixed reality(MR) technology that the shared experiences rely on,proper software and hardware platforms were investigated and selected,a universal shared experiences solution was designed,and an experimental project based on the proposed solution was made to verify its feasibility.In the end,a proven and workable shared experiences solution was obtained.This solution included a proposed MR spatial alignment method,and it integrated the existing MR content production process and standard network synchronization functions.Furthermore,it is concluded that the introduction and reasonable use of new technologies can help the development of the digital interactive experience of cultural heritage.The shared experiences solution for the digital interactive experience of cultural heritage balances investment issues in the exhibition,display effect,and user experience.It can speed up the promotion of cultural heritage and bring the vitality of MR technology to relevant projects.
