In this letter, we analyze the drawback of tail-dropping contention resolution in optical burst switched networks. Once contention occurs, we adopt modified head-dropping policy to resolve contention. This policy drop...In this letter, we analyze the drawback of tail-dropping contention resolution in optical burst switched networks. Once contention occurs, we adopt modified head-dropping policy to resolve contention. This policy drops the head of the contending burst only if the overlapping region of the two bursts is less than the whole contending burst size, otherwise drops the whole contending burst. In order to have a better support of differentiated service, a new burst assembly policy, namely, Priority-based proportional mixed burst assembly, is proposed. Simulation results show that the proposed scheme performs very well in terms of performance metrics such as the times of contention and packet loss probability.展开更多
In order to have a better support of differentiated service, we propose Priority-based mixed burst assembly, in which packets of different priorities are assembled in a burst with an assigned proportion, and the prior...In order to have a better support of differentiated service, we propose Priority-based mixed burst assembly, in which packets of different priorities are assembled in a burst with an assigned proportion, and the priorities are lined in an ascending order in a burst from head to tail. Simulation results show that the proposed scheme performs very well in terms of latency and packet loss probability.展开更多
Hair cell regeneration is the fundamental method of correcting hearing loss and balance disorders caused by hair cell damage or loss. How to promote hair cell regeneration is a hot focus in current research. In mammal...Hair cell regeneration is the fundamental method of correcting hearing loss and balance disorders caused by hair cell damage or loss. How to promote hair cell regeneration is a hot focus in current research. In mammals, cochlear hair cells cannot be regenerated and few vestibular hair cells can be renewed through spontaneous regeneration. However, Math1 gene transfer allows a few inner ear cells to be transformed into hair cells in vitro or in vivo. Hair cells can be renewed through two possible means in birds： supporting cell differentiation and transdifferentiation with or without cell division. Hair cell regeneration is strongly associated with cell proliferation. Therefore, this study explored the relationship between Math1-induced vestibular hair cell regeneration and cell division in mammals. The mouse vestibule was isolated to harvest vestibular epithelial cells. Ad-Math1-enhanced green fluorescent protein （EGFP） was used to track cell division during hair cell transformation.5-Bromo-2′-deoxyuridine （BrdU） was added to track cell proliferation at various time points. Immunocytochemistry was utilized to determine cell differentiation and proliferation. Results demonstrated that when epithelial cells were in a higher proliferative stage, more of these cells differentiated into hair cells by Math1 gene transfer. However, in the low proliferation stage, no BrdU-positive cells were seen after Math1 gene transfer. Cell division always occurred before Math1 transfection but not during or after Math1 transfection, when cells were labeled with BrdU before and after Ad-Math1-EGFP transfection. These results confirm that vestibular epithelial cells with high proliferative potential can differentiate into new hair cells by Math1 gene transfer, but this process is independent of cell proliferation.展开更多
基金This work was partially supported by the National Natural Science Foundation of China under Grant No. 69990540.
文摘In this letter, we analyze the drawback of tail-dropping contention resolution in optical burst switched networks. Once contention occurs, we adopt modified head-dropping policy to resolve contention. This policy drops the head of the contending burst only if the overlapping region of the two bursts is less than the whole contending burst size, otherwise drops the whole contending burst. In order to have a better support of differentiated service, a new burst assembly policy, namely, Priority-based proportional mixed burst assembly, is proposed. Simulation results show that the proposed scheme performs very well in terms of performance metrics such as the times of contention and packet loss probability.
基金This work is partially supported by the National Natural Science Foundation of China under contract 69990540.
文摘In order to have a better support of differentiated service, we propose Priority-based mixed burst assembly, in which packets of different priorities are assembled in a burst with an assigned proportion, and the priorities are lined in an ascending order in a burst from head to tail. Simulation results show that the proposed scheme performs very well in terms of latency and packet loss probability.
基金supported by the National Natural Science Foundation of China(NSFC)grant No.81420108010,81271084 to FLC,81370022,81570920,81000413 to DR,81200740 to JMY,81200738 to NC,81371093 to ZH,81400460 to ZG,81200739 to JW+2 种基金973 Program,grant No.2011CB504500 and 2011CB504506The Innovation Project of Shanghai Municipal Science and Technology Commission,grant No.11411952300 to FLCthe Training Program of the Excellent Young Talents of the Shanghai Municipal Health System,grant No.XYQ2013084 to DR
文摘Hair cell regeneration is the fundamental method of correcting hearing loss and balance disorders caused by hair cell damage or loss. How to promote hair cell regeneration is a hot focus in current research. In mammals, cochlear hair cells cannot be regenerated and few vestibular hair cells can be renewed through spontaneous regeneration. However, Math1 gene transfer allows a few inner ear cells to be transformed into hair cells in vitro or in vivo. Hair cells can be renewed through two possible means in birds： supporting cell differentiation and transdifferentiation with or without cell division. Hair cell regeneration is strongly associated with cell proliferation. Therefore, this study explored the relationship between Math1-induced vestibular hair cell regeneration and cell division in mammals. The mouse vestibule was isolated to harvest vestibular epithelial cells. Ad-Math1-enhanced green fluorescent protein （EGFP） was used to track cell division during hair cell transformation.5-Bromo-2′-deoxyuridine （BrdU） was added to track cell proliferation at various time points. Immunocytochemistry was utilized to determine cell differentiation and proliferation. Results demonstrated that when epithelial cells were in a higher proliferative stage, more of these cells differentiated into hair cells by Math1 gene transfer. However, in the low proliferation stage, no BrdU-positive cells were seen after Math1 gene transfer. Cell division always occurred before Math1 transfection but not during or after Math1 transfection, when cells were labeled with BrdU before and after Ad-Math1-EGFP transfection. These results confirm that vestibular epithelial cells with high proliferative potential can differentiate into new hair cells by Math1 gene transfer, but this process is independent of cell proliferation.
