Geography influences the culture of one nation deeply.Due to the oceanic and continental differences-Britain locates herself in the islands of the north temperate zone while China is located in the Eurasia,the culture...Geography influences the culture of one nation deeply.Due to the oceanic and continental differences-Britain locates herself in the islands of the north temperate zone while China is located in the Eurasia,the cultures of the two countries are differ ent sharply.The idioms,as the crystallization of languages and sedimentation,come from people's daily life and are shaped by the oceanic 、continental difference largely.This article will analyze the translations between the English-Chinese idioms in the per spective of oceanic and continental culture.展开更多
Objective:To investigate the effects of Gastrodiae rhizoma,a dried root of Gastrodia elata Blume,on proliferation and differentiation of human NSCs derived from embryonic stem cells.Methods:A 70%ethanol extract of Gas...Objective:To investigate the effects of Gastrodiae rhizoma,a dried root of Gastrodia elata Blume,on proliferation and differentiation of human NSCs derived from embryonic stem cells.Methods:A 70%ethanol extract of Gastrodiae rhizoma(EEGR) was estimated with4-hydroxybenzyl alcohol as a representative constituent by HPLC.Results:MTT assay showed that the treatment with EEGR increased the viability of NSCs in growth media.Compared to contro1,EEGR increased the number of dendrites and denritic spines extended from a differentiated NSC.Whereas EEGR decreased the mRNA expression of Nestin,it increased that of Tuj1 and MAP2 in NSCs grown in differentiation media.Immunocytochemical analysis using confocal microscopy also revealed the increased expression of MAP2 in dendrites of EEGR-treated NSCs.Furthermore,EEGR decreased mRNA expression of Sox2 in NSCs grown even in growth media.Conclusions:In conclusion,our study demonstrates for the first time that EEGR induced proliferation and neuronal differentiation of NSCs,suggesting its potential benefits on NSC-based therapies and neuroregeneration in various neurodegenerative diseases and brain Injuries.展开更多
Idesia polycarpa Maxim.var vestita Diels.is a dioecious tree species native to eastern Asia.There are diffi culties associated with distinguishing the sex of the plant at the seedling stage.In order to explore the mec...Idesia polycarpa Maxim.var vestita Diels.is a dioecious tree species native to eastern Asia.There are diffi culties associated with distinguishing the sex of the plant at the seedling stage.In order to explore the mechanism of sex diff erentiation in fl ower development,we conducted the transcriptome profi les of male and female fl owers at early,metaphase and late developmental stages.Approximately 123,335 unigenes with a total length of 83,996 Mb and an average length of 168 bp were assembled.The unigenes were blasted into Nr,Nt,Pfam,KOG/COG,Swiss-prot,KEGG,GO databases.Homology analysis demonstrated that I.polycarpa and black cottonwood had the highest homology with the alignment of 92,871 sequences.This study identifi ed 80 groups of transcription factor families with a total of 1475 unigenes,mainly including MYB,WRKY,AP2 and bHLH transcription factor families.KEGG pathway analysis showed that the expression of numerous plant hormones(cytokinin,gibberellin and ethylene)and fl avonoid biosynthesis pathway were diff erent at various stages of female and male fl ower development.In addition,a number of unigenes associated with fl owering were identifi ed which were key genes associated with photoperiodic,vernalization,thermosensory,gibberellin,and autonomic pathways.The results show that I.polycarpa fl oral organ development was in accordance with the ABCDE model,in which the down-regulation of the B gene family might aff ect stamen fertility in late stages of female fl ower development.qRTPCR experiments validated that the expression patterns of 15 unigenes were consistent with those in RNA-seq results.The results highlight a central role for plant sex identifi cation in seedling production and a sex-determining mechanism for dioecious plants.In addition,the transcriptome data provided a theoretical basis for I.polycarpa genetic diversity analysis and molecular-assisted breeding.展开更多
When a seismic wave propagates through subsurface viscoelastic media,the formation absorbs the high-frequency energy of the seismic wave more strongly than the low-frequency energy.As the depth and the off set increas...When a seismic wave propagates through subsurface viscoelastic media,the formation absorbs the high-frequency energy of the seismic wave more strongly than the low-frequency energy.As the depth and the off set increase,the diff erence between the logarithmic spectral areas with high and low frequencies gradually increases.Based on this seismic wave characteristic,we have developed a novel Q-estimation method based on logarithmic spectral area diff erence of high and low frequencies(referred to as the LSAD_LH method).In this paper,we derive the theoretical relationship between the Q value and difference of logarithmic spectral areas with high and low frequencies and prove the applicability of the LSAD_LH method using a single-layer medium numerical model.To verify the sensitivity of the LSAD_LH method to bandwidth selection and noise,we compare the LSAD_LH method with two credible methods—the logarithmic spectral ratio(LSR)and logarithmic spectral area diff erence(LSAD)methods using a synthetic model containing the random noise.The results demonstrate that the LSAD_LH method is not highly dependent on bandwidth,and in terms of noise immunity,it is signifi cantly better than the LSR method and has the same advantages as the LSAD method.To further highlight the advantages of the LSAD_LH method,we apply the LSAD_LH and LSAD methods to the vertical seismic profi ling(VSP)numerical simulation of the multilayer media and the fi eld zero-off set VSP data.The application of the two cases proves the applicability of the LSAD_LH method and the accuracy of the high Q-value estimation relative to the LSAD method.Moreover,via the transmission coeffi cient,the LSAD_LH method overcomes the weakness of the LSAD method.展开更多
Walt Whitman and Emily Dickinson are known as original geniuses in American literature. There exist both similarities and differences between Whitman and Dickinson. This paper will discuss the similarities and differe...Walt Whitman and Emily Dickinson are known as original geniuses in American literature. There exist both similarities and differences between Whitman and Dickinson. This paper will discuss the similarities and differences between these two outstanding American poets from several aspects, such as their lives, literary styles, themes and poetic techniques.展开更多
A coal seam is thin compared to the wavelength of seismic waves and usually shows strong anisotropy.It may form special geological formations,such as goafs and collapses,in coal mines.The existence of these formations...A coal seam is thin compared to the wavelength of seismic waves and usually shows strong anisotropy.It may form special geological formations,such as goafs and collapses,in coal mines.The existence of these formations may lead to instability in numerical simulations of the goaf area in a coal seam.The calculation speed of simulations is always a factor that restricts the development of simulation techniques.To improve the accuracy and effi ciency of seismic numerical simulations of goaf areas,an improved vacuum method has been incorporated into a rotated staggered grid scheme and calculations implemented by combining parallel computing and task parallelism.This ensures that the proposed numerical simulation method can be utilized in a geological model with large differences in elastic parameters among layers and improve the performance of a parallel application by enabling the full use of processor resources to expedite the calculations.We set up anisotropic coal seam models and then analyze numerically the characteristics of synthetic seismograms and snapshots of diff erent goaf areas with or without collapse.The results show that the proposed method can accurately simulate the goaf area and the calculation method can run with a high speed and parallel efficiency.The research will further advance the technology of anisotropic seismic exploration in coal fi elds,provide data for seismic inversion and build a theoretical support for coal mine disaster prediction.展开更多
Although earthquake lights have been known since ancient times,it has not been easy to study them.It was not until the 60s that the first photographs of them were taken.During the Peruvian earthquake in 2007,it was po...Although earthquake lights have been known since ancient times,it has not been easy to study them.It was not until the 60s that the first photographs of them were taken.During the Peruvian earthquake in 2007,it was possible to obtain the fi rst fi lm recording on earthquake lights.Likewise,during the earthquakes in Ecuador in 2016 and in Mexico in 2017,two fi lms of the earthquake lights were recorded.These fi lm recordings have helped in the study of earthquake lights,both for their objectivity and for their informational content.Several causal mechanisms have been proposed to explain earthquake lights:piezoelectricity,radon emanation,fluid diffusion,friction-vaporization,positive holes and dipole currents,among others.In this work a time difference correlation between earthquake lights and seismic ground accelerations was found and we use both seismic data and fi lm recordings of earthquake lights to explain its origin.In the discussion section it is suggested that fracturing of rocks manifest itself to some extent in the form of static electricity producing earthquake lights through induction The induction model proposed is new and it can explain the formation of EQL,even if the earth’s crust has layers of large electrical resistivity.The model also explains the formation of seismic lights without the need for special conditions on the earth’s surface or in the atmosphere.A better understanding of the earthquake lights generation process can improve our understanding of seismicity and help in the prediction of earthquakes.展开更多
In this paper,we will discuss smoothness of weak solutions for the system of second order differential equations eith non-negative characteristies.First of all,we establish boundary,and interior estimates and then we ...In this paper,we will discuss smoothness of weak solutions for the system of second order differential equations eith non-negative characteristies.First of all,we establish boundary,and interior estimates and then we prove that solutions of regularization problem satisfy Lipschitz condition.展开更多
In slowly deforming intraplate regions,identifying active faults is challenging due to their low slip rates or concealment by recent sedimentation and anthropogenic activity,requiring significant time and resources.We...In slowly deforming intraplate regions,identifying active faults is challenging due to their low slip rates or concealment by recent sedimentation and anthropogenic activity,requiring significant time and resources.We focus on the structural features and spatial extent of a buried active reverse fault,central South Korea.Our approach integrates the structural and paleoseismic records from the fault exposure with 2D and 3D electrical resistivity surveys.In the road construction area,electrical resistivity differentiates the fault’s hanging wall from the footwall in granitic bedrock.展开更多
文摘Geography influences the culture of one nation deeply.Due to the oceanic and continental differences-Britain locates herself in the islands of the north temperate zone while China is located in the Eurasia,the cultures of the two countries are differ ent sharply.The idioms,as the crystallization of languages and sedimentation,come from people's daily life and are shaped by the oceanic 、continental difference largely.This article will analyze the translations between the English-Chinese idioms in the per spective of oceanic and continental culture.
基金supported by Grant of the Traditional Korean Medicine R&D Project,Ministry of Health and Welfare,Republic of Korea(HI13C0516)the National Research Foundation of Korea(NRF)grand funded by the Korea government(MSIP)(No.2008-0062484)
文摘Objective:To investigate the effects of Gastrodiae rhizoma,a dried root of Gastrodia elata Blume,on proliferation and differentiation of human NSCs derived from embryonic stem cells.Methods:A 70%ethanol extract of Gastrodiae rhizoma(EEGR) was estimated with4-hydroxybenzyl alcohol as a representative constituent by HPLC.Results:MTT assay showed that the treatment with EEGR increased the viability of NSCs in growth media.Compared to contro1,EEGR increased the number of dendrites and denritic spines extended from a differentiated NSC.Whereas EEGR decreased the mRNA expression of Nestin,it increased that of Tuj1 and MAP2 in NSCs grown in differentiation media.Immunocytochemical analysis using confocal microscopy also revealed the increased expression of MAP2 in dendrites of EEGR-treated NSCs.Furthermore,EEGR decreased mRNA expression of Sox2 in NSCs grown even in growth media.Conclusions:In conclusion,our study demonstrates for the first time that EEGR induced proliferation and neuronal differentiation of NSCs,suggesting its potential benefits on NSC-based therapies and neuroregeneration in various neurodegenerative diseases and brain Injuries.
文摘Idesia polycarpa Maxim.var vestita Diels.is a dioecious tree species native to eastern Asia.There are diffi culties associated with distinguishing the sex of the plant at the seedling stage.In order to explore the mechanism of sex diff erentiation in fl ower development,we conducted the transcriptome profi les of male and female fl owers at early,metaphase and late developmental stages.Approximately 123,335 unigenes with a total length of 83,996 Mb and an average length of 168 bp were assembled.The unigenes were blasted into Nr,Nt,Pfam,KOG/COG,Swiss-prot,KEGG,GO databases.Homology analysis demonstrated that I.polycarpa and black cottonwood had the highest homology with the alignment of 92,871 sequences.This study identifi ed 80 groups of transcription factor families with a total of 1475 unigenes,mainly including MYB,WRKY,AP2 and bHLH transcription factor families.KEGG pathway analysis showed that the expression of numerous plant hormones(cytokinin,gibberellin and ethylene)and fl avonoid biosynthesis pathway were diff erent at various stages of female and male fl ower development.In addition,a number of unigenes associated with fl owering were identifi ed which were key genes associated with photoperiodic,vernalization,thermosensory,gibberellin,and autonomic pathways.The results show that I.polycarpa fl oral organ development was in accordance with the ABCDE model,in which the down-regulation of the B gene family might aff ect stamen fertility in late stages of female fl ower development.qRTPCR experiments validated that the expression patterns of 15 unigenes were consistent with those in RNA-seq results.The results highlight a central role for plant sex identifi cation in seedling production and a sex-determining mechanism for dioecious plants.In addition,the transcriptome data provided a theoretical basis for I.polycarpa genetic diversity analysis and molecular-assisted breeding.
基金National Nature Science Foundation of China(Grant No.U1562110)。
文摘When a seismic wave propagates through subsurface viscoelastic media,the formation absorbs the high-frequency energy of the seismic wave more strongly than the low-frequency energy.As the depth and the off set increase,the diff erence between the logarithmic spectral areas with high and low frequencies gradually increases.Based on this seismic wave characteristic,we have developed a novel Q-estimation method based on logarithmic spectral area diff erence of high and low frequencies(referred to as the LSAD_LH method).In this paper,we derive the theoretical relationship between the Q value and difference of logarithmic spectral areas with high and low frequencies and prove the applicability of the LSAD_LH method using a single-layer medium numerical model.To verify the sensitivity of the LSAD_LH method to bandwidth selection and noise,we compare the LSAD_LH method with two credible methods—the logarithmic spectral ratio(LSR)and logarithmic spectral area diff erence(LSAD)methods using a synthetic model containing the random noise.The results demonstrate that the LSAD_LH method is not highly dependent on bandwidth,and in terms of noise immunity,it is signifi cantly better than the LSR method and has the same advantages as the LSAD method.To further highlight the advantages of the LSAD_LH method,we apply the LSAD_LH and LSAD methods to the vertical seismic profi ling(VSP)numerical simulation of the multilayer media and the fi eld zero-off set VSP data.The application of the two cases proves the applicability of the LSAD_LH method and the accuracy of the high Q-value estimation relative to the LSAD method.Moreover,via the transmission coeffi cient,the LSAD_LH method overcomes the weakness of the LSAD method.
文摘Walt Whitman and Emily Dickinson are known as original geniuses in American literature. There exist both similarities and differences between Whitman and Dickinson. This paper will discuss the similarities and differences between these two outstanding American poets from several aspects, such as their lives, literary styles, themes and poetic techniques.
基金This work was supported by the National Natural Science Foundation of China(Nos.41304105 and 41674135)the Natural Science Foundation of Shaanxi province(No.2016JM4010).
文摘A coal seam is thin compared to the wavelength of seismic waves and usually shows strong anisotropy.It may form special geological formations,such as goafs and collapses,in coal mines.The existence of these formations may lead to instability in numerical simulations of the goaf area in a coal seam.The calculation speed of simulations is always a factor that restricts the development of simulation techniques.To improve the accuracy and effi ciency of seismic numerical simulations of goaf areas,an improved vacuum method has been incorporated into a rotated staggered grid scheme and calculations implemented by combining parallel computing and task parallelism.This ensures that the proposed numerical simulation method can be utilized in a geological model with large differences in elastic parameters among layers and improve the performance of a parallel application by enabling the full use of processor resources to expedite the calculations.We set up anisotropic coal seam models and then analyze numerically the characteristics of synthetic seismograms and snapshots of diff erent goaf areas with or without collapse.The results show that the proposed method can accurately simulate the goaf area and the calculation method can run with a high speed and parallel efficiency.The research will further advance the technology of anisotropic seismic exploration in coal fi elds,provide data for seismic inversion and build a theoretical support for coal mine disaster prediction.
文摘Although earthquake lights have been known since ancient times,it has not been easy to study them.It was not until the 60s that the first photographs of them were taken.During the Peruvian earthquake in 2007,it was possible to obtain the fi rst fi lm recording on earthquake lights.Likewise,during the earthquakes in Ecuador in 2016 and in Mexico in 2017,two fi lms of the earthquake lights were recorded.These fi lm recordings have helped in the study of earthquake lights,both for their objectivity and for their informational content.Several causal mechanisms have been proposed to explain earthquake lights:piezoelectricity,radon emanation,fluid diffusion,friction-vaporization,positive holes and dipole currents,among others.In this work a time difference correlation between earthquake lights and seismic ground accelerations was found and we use both seismic data and fi lm recordings of earthquake lights to explain its origin.In the discussion section it is suggested that fracturing of rocks manifest itself to some extent in the form of static electricity producing earthquake lights through induction The induction model proposed is new and it can explain the formation of EQL,even if the earth’s crust has layers of large electrical resistivity.The model also explains the formation of seismic lights without the need for special conditions on the earth’s surface or in the atmosphere.A better understanding of the earthquake lights generation process can improve our understanding of seismicity and help in the prediction of earthquakes.
文摘In this paper,we will discuss smoothness of weak solutions for the system of second order differential equations eith non-negative characteristies.First of all,we establish boundary,and interior estimates and then we prove that solutions of regularization problem satisfy Lipschitz condition.
基金supported by a grant(2022-MOIS62-001)for National Disaster Risk Analysis and Management Technology in Earthquakes funded by the Ministry of Interior and Safety(MOIS,South Korea).
文摘In slowly deforming intraplate regions,identifying active faults is challenging due to their low slip rates or concealment by recent sedimentation and anthropogenic activity,requiring significant time and resources.We focus on the structural features and spatial extent of a buried active reverse fault,central South Korea.Our approach integrates the structural and paleoseismic records from the fault exposure with 2D and 3D electrical resistivity surveys.In the road construction area,electrical resistivity differentiates the fault’s hanging wall from the footwall in granitic bedrock.
