1,3,5-Trisubstituted pyrazolines are rapidly and conveniently oxidized to their corresponding pyrazoles by 1,3-dichloro-5,5- dimethylhydantoin（DCH） in solution and solvent-free conditions under microwave irradiation...1,3,5-Trisubstituted pyrazolines are rapidly and conveniently oxidized to their corresponding pyrazoles by 1,3-dichloro-5,5- dimethylhydantoin（DCH） in solution and solvent-free conditions under microwave irradiation.The presence of silica gel as a supporting agent is shown to be effective in reducing the reaction times and increasing the yields.展开更多
Soil-air partitioning is an important diffusive process that affects the environmental fate of organic compounds and human health. In this review, factors affecting the soil-air partitioning of polychlorinated bipheny...Soil-air partitioning is an important diffusive process that affects the environmental fate of organic compounds and human health. In this review, factors affecting the soil-air partitioning of polychlorinated biphenyls （PCBs） and total dichloro-diphenyl-trichloroethanes （p,p＇- and o,p＇- isomers of DDT, DDD, and DDE） are discussed. Hydrophobicity is an important factor that influences soil-air partition coefficients （KsA）, and its effect can be explained through enthalpy of phase change for soil-air partitioning transfer （AHsA）. For more hydrophobic compounds, a sharp increase in the KSA of PCBs and organochlorines can be seen in the early aging period. During the aging period, the temperature has a significant effect on the more hydrophobic organic compounds. The content and properties of soil or- ganic matter influence the KSA of the target compounds. Generally, KSA decreases with increasing rela- tive humidity in soils. The linear trend between KSA and temperature （T） changes at 0 ~C. Freezing the air or soil in experiments would change the research results. On the basis of factors influencing soil-air partitioning, a multipleparameter （T, organic carbon fraction （foe）, and octanol-air partition coefficient （KoA）） model is put forward to predict the KSA values for PCBs and total DDTs.展开更多
The reactive properties of 1,3-dichloro-1,1,3,3-tetraphenyldisilazane (DCTPS) with water, methanol, phenylamine and lithium salt of hexamethylcyclotrisilazane (D-3(NLi)) were investigated, and four new derivatives wer...The reactive properties of 1,3-dichloro-1,1,3,3-tetraphenyldisilazane (DCTPS) with water, methanol, phenylamine and lithium salt of hexamethylcyclotrisilazane (D-3(NLi)) were investigated, and four new derivatives were obtained.展开更多
Novel compounds, （3,6-dichloro-2-nitrophenyl）（3-nitrophenyl）methanone（2）, （2-amino-3,6-dichloro- phenyl）（3-aminophenyl）methanone（3） and 1-[3-（2-amino-3,6-dichlorobenzoyl）phenyl]-1H-pyrrole-2,5-dione（4）...Novel compounds, （3,6-dichloro-2-nitrophenyl）（3-nitrophenyl）methanone（2）, （2-amino-3,6-dichloro- phenyl）（3-aminophenyl）methanone（3） and 1-[3-（2-amino-3,6-dichlorobenzoyl）phenyl]-1H-pyrrole-2,5-dione（4）, were synthesized from the initial compound 2,5-dichlorobenzophenone（1） and characterized by 1H NMR, 13C NMR, IR, mass spectrum and element analysis, respectively. The single crystal of compound 2 was obtained and determined by X-ray diffraction analysis. The single crystal data illustrates that it belongs to the monoclinic system, space group P21/c with a=0.7587（4） nm, b=2.4724（4） nm, c=0.8081（3） nm, α=90°, β=112.85（2）°, γ=90o, V=1.3970（9） nm3, Z=4, Dc=1.622 g/cm3, Mr（C13H6Cl2N2O5）=341.10, μ（Mo Kα）=0.49 mm？1, F（000）=688, the final R=0.048 and wR=0.144 for 1665 observed reflections with I2σ（I）. The title molecule forms a ＂T＂ type crystal structure and the dihedral angel of the two phenyl rings is 65.0（1）°.展开更多
The synthetic method of dithianon intermediate 2,3-dichloro-1,4-naphthoquinone was introduced. Starting with raw material sodium 4-amino1-naphthalene sulfonate, 2,3-dichloro-1,4-naphthoquinone was synthesized through ...The synthetic method of dithianon intermediate 2,3-dichloro-1,4-naphthoquinone was introduced. Starting with raw material sodium 4-amino1-naphthalene sulfonate, 2,3-dichloro-1,4-naphthoquinone was synthesized through acidification, chlorination and oxidation. After filtration and recrystallization, more than 98% of 2,3-dichloro-1,4-naphthoquinone was obtained, and the yield reached 76%(measured by sodium 4-amino-1-naphthalene sulfonate).展开更多
3-Amino-2-methoxycarbonylthiophene used as the main raw material,an intermediate（thiofuran siamese） 2,4-dichloro-thieno[3,2-d]pyrimidine was synthesized.The prod-uct was characterized by nuclear magnetic resonance（...3-Amino-2-methoxycarbonylthiophene used as the main raw material,an intermediate（thiofuran siamese） 2,4-dichloro-thieno[3,2-d]pyrimidine was synthesized.The prod-uct was characterized by nuclear magnetic resonance（NMR）.The first step yield was 84%（190 ℃） and the second step yield was 81.4%（105 ℃,m（intermediate）：m（phosphorus oxychloride） = 1：6.4）.The raw product was refined with a unique refining process,which can enhance the purity up to 99.5% to meet the requirement of condi-tions for the development and research of thiofuran siamese as a new medicine of anticarcinogen.Contrasted with the traditional technique,this process featured with cheap raw materials,possible for solvent recovery and reuse,low comprehensive cost,and suit-able for production on certain scale.展开更多
An efficient catalytic asymmetric chlorocyclization of olefinic amides with 1,3-dichloro-5,5-dimethylhydantoin（DCDMH） using hydroquinidine 1,4-phthalazinediyl diether（（DHQD）_2 PHAL） as organocatalyst has been de...An efficient catalytic asymmetric chlorocyclization of olefinic amides with 1,3-dichloro-5,5-dimethylhydantoin（DCDMH） using hydroquinidine 1,4-phthalazinediyl diether（（DHQD）_2 PHAL） as organocatalyst has been developed. Series of chiral chloro substituted isobenzofuran-1（3 H）-imine derivatives were obtained in good yields（up to 85%） and enantioselectivities（up to 70% ee）.展开更多
Bis{2-[（2,4-dichloro-phenytimino）-methyl]-4,6-diiodo-phenol}-copper（II） （1） has been synthesized and its structure determined by X-ray diffraction. It crystallizes in the monoclinic system, space group P21/n wit...Bis{2-[（2,4-dichloro-phenytimino）-methyl]-4,6-diiodo-phenol}-copper（II） （1） has been synthesized and its structure determined by X-ray diffraction. It crystallizes in the monoclinic system, space group P21/n with a = 14.7558（17）, b = 20.770（2）, c = 20.3260（19） A, β = 90.6110（10）°, V= 6229.2（11） A3 and Z = 8. The Cu atom is surrounded by two O atoms and two N atoms from two 2-[（2,4-diehloro-phenylimino）-methyl]-4,6-diiodo-phenol molecules to form a tetrahedral coordination environment. The complex is linked into a column by weak intermolecular interactions.展开更多
The amide herbicide has been studied systematically in our laboratory for many years. We have synthesized 74 kinds of amide-compounds, most of which are aliphatic amides and the others are furfural and aromatic amides...The amide herbicide has been studied systematically in our laboratory for many years. We have synthesized 74 kinds of amide-compounds, most of which are aliphatic amides and the others are furfural and aromatic amides. It has been found that the N-3′, 4′-dichloro-α-methyl-propionanilide (DCMPA) behaves as effective as N-3.4-dichloro-展开更多
Condensation of D-glucose, o-phenylenediamine and N,N-benzylphenylhydrazine hydrochloride (NNBPHH) in a one-pot reaction, or condensation of 2-(D-arabino-tetritol-1-yl) quinoxaline and NNBPHH, gave 3-(D-erythro-glycer...Condensation of D-glucose, o-phenylenediamine and N,N-benzylphenylhydrazine hydrochloride (NNBPHH) in a one-pot reaction, or condensation of 2-(D-arabino-tetritol-1-yl) quinoxaline and NNBPHH, gave 3-(D-erythro-glycerol-1- yl)-1-phenyl-1H-pyrazolo[3,4-b]quinoxaline. The structure of the latter was determined by 1H NMR spectroscopy and by synthesis using phenylhydrazine hydrochloride instead of NNBPHH. Condensation of D-glucose and 4,5-dichloro-o-phenylenediamine gave 6,7-dichloro-2-(D-arabino-tetritol-1-yl)quinoxaline, which upon condensation with NNBPHH gave the corresponding 6,7-dichloro-3-(D-erythro-glycerol-1-yl)-1-phenyl-1H-pyrazolo[3,4-b]quinoxaline. The structure and mechanism of formation of these compounds are discussed.展开更多
A 24-metal Cd_((II))-Sm_((III))nanocluster[Cd_(18)Sm_(6)L_(9)(OAc)_(3)_(6)](CSN)was constructed from a new flexible Schiff base ligand.It can be used as a probe to detect 2,6-dichloro-4-nitroaniline(DCN,LOD:0.67-0.75...A 24-metal Cd_((II))-Sm_((III))nanocluster[Cd_(18)Sm_(6)L_(9)(OAc)_(3)_(6)](CSN)was constructed from a new flexible Schiff base ligand.It can be used as a probe to detect 2,6-dichloro-4-nitroaniline(DCN,LOD:0.67-0.75μM),which is not influenced by the presence of other pesticides.The response behavior of CSN to DCN is expressed using a first-order equation 1/I_(475nm)+1/I_(645nm)+1/I_(945nm)=A[DCN]+B,and it is used to determine DCN concentrations in the extract of fruits.For example,for the concentration determination of DCN in carrot extract,the ranges of recovery and RSD are 96.11-103.50%and 0.95-4.12%,respectively.展开更多
As a good antimicrobial active ingredient, 2,4,4′ trichloro 2′ hydroxydiphenyl ether has been already commercially available since 1970s. For this paper halogenated hydroxydiphenyl ethers were prepared and purifi...As a good antimicrobial active ingredient, 2,4,4′ trichloro 2′ hydroxydiphenyl ether has been already commercially available since 1970s. For this paper halogenated hydroxydiphenyl ethers were prepared and purified, and their analytical conditions by HPLC were studied. Further purification of 2,4,4′ trichloro 2′ hydroxydiphenyl ether was also studied. The adsorption ability of different decolourants, e.g. alumina and bentonite, for each component in crude product of 2,4,4′ trichloro 2′ hydroxydiphenyl ether was varied. 2,4,4′ trichloro 2′ hydroxydiphenyl ether might be adsorbed by active carbon. The colored impurities might be adsorbed by alumina. The colorless impurities might be adsorbed by bentonite.展开更多
文摘1,3,5-Trisubstituted pyrazolines are rapidly and conveniently oxidized to their corresponding pyrazoles by 1,3-dichloro-5,5- dimethylhydantoin（DCH） in solution and solvent-free conditions under microwave irradiation.The presence of silica gel as a supporting agent is shown to be effective in reducing the reaction times and increasing the yields.
基金supported by the National Natural Science Foundation of China (No. 41172223)the Fundamental Research Funds for the Central Universities (No. 2652012089)the Commonwealth and Environmental Protection Project of the Ministry of Environmental Protection of the People’s Republic of China (No. 201209053)
文摘Soil-air partitioning is an important diffusive process that affects the environmental fate of organic compounds and human health. In this review, factors affecting the soil-air partitioning of polychlorinated biphenyls （PCBs） and total dichloro-diphenyl-trichloroethanes （p,p＇- and o,p＇- isomers of DDT, DDD, and DDE） are discussed. Hydrophobicity is an important factor that influences soil-air partition coefficients （KsA）, and its effect can be explained through enthalpy of phase change for soil-air partitioning transfer （AHsA）. For more hydrophobic compounds, a sharp increase in the KSA of PCBs and organochlorines can be seen in the early aging period. During the aging period, the temperature has a significant effect on the more hydrophobic organic compounds. The content and properties of soil or- ganic matter influence the KSA of the target compounds. Generally, KSA decreases with increasing rela- tive humidity in soils. The linear trend between KSA and temperature （T） changes at 0 ~C. Freezing the air or soil in experiments would change the research results. On the basis of factors influencing soil-air partitioning, a multipleparameter （T, organic carbon fraction （foe）, and octanol-air partition coefficient （KoA）） model is put forward to predict the KSA values for PCBs and total DDTs.
基金The project is supported by the National Natural Science Foundation of China.No.50072033 and No.20074040.
文摘The reactive properties of 1,3-dichloro-1,1,3,3-tetraphenyldisilazane (DCTPS) with water, methanol, phenylamine and lithium salt of hexamethylcyclotrisilazane (D-3(NLi)) were investigated, and four new derivatives were obtained.
文摘Novel compounds, （3,6-dichloro-2-nitrophenyl）（3-nitrophenyl）methanone（2）, （2-amino-3,6-dichloro- phenyl）（3-aminophenyl）methanone（3） and 1-[3-（2-amino-3,6-dichlorobenzoyl）phenyl]-1H-pyrrole-2,5-dione（4）, were synthesized from the initial compound 2,5-dichlorobenzophenone（1） and characterized by 1H NMR, 13C NMR, IR, mass spectrum and element analysis, respectively. The single crystal of compound 2 was obtained and determined by X-ray diffraction analysis. The single crystal data illustrates that it belongs to the monoclinic system, space group P21/c with a=0.7587（4） nm, b=2.4724（4） nm, c=0.8081（3） nm, α=90°, β=112.85（2）°, γ=90o, V=1.3970（9） nm3, Z=4, Dc=1.622 g/cm3, Mr（C13H6Cl2N2O5）=341.10, μ（Mo Kα）=0.49 mm？1, F（000）=688, the final R=0.048 and wR=0.144 for 1665 observed reflections with I2σ（I）. The title molecule forms a ＂T＂ type crystal structure and the dihedral angel of the two phenyl rings is 65.0（1）°.
文摘The synthetic method of dithianon intermediate 2,3-dichloro-1,4-naphthoquinone was introduced. Starting with raw material sodium 4-amino1-naphthalene sulfonate, 2,3-dichloro-1,4-naphthoquinone was synthesized through acidification, chlorination and oxidation. After filtration and recrystallization, more than 98% of 2,3-dichloro-1,4-naphthoquinone was obtained, and the yield reached 76%(measured by sodium 4-amino-1-naphthalene sulfonate).
基金Supported by the Innovation Fund for Technology Based Firms (10C26224212340)
文摘3-Amino-2-methoxycarbonylthiophene used as the main raw material,an intermediate（thiofuran siamese） 2,4-dichloro-thieno[3,2-d]pyrimidine was synthesized.The prod-uct was characterized by nuclear magnetic resonance（NMR）.The first step yield was 84%（190 ℃） and the second step yield was 81.4%（105 ℃,m（intermediate）：m（phosphorus oxychloride） = 1：6.4）.The raw product was refined with a unique refining process,which can enhance the purity up to 99.5% to meet the requirement of condi-tions for the development and research of thiofuran siamese as a new medicine of anticarcinogen.Contrasted with the traditional technique,this process featured with cheap raw materials,possible for solvent recovery and reuse,low comprehensive cost,and suit-able for production on certain scale.
基金Supported by the Fundamental Research Funds for the Central Universities of China(2015306020201)
文摘An efficient catalytic asymmetric chlorocyclization of olefinic amides with 1,3-dichloro-5,5-dimethylhydantoin（DCDMH） using hydroquinidine 1,4-phthalazinediyl diether（（DHQD）_2 PHAL） as organocatalyst has been developed. Series of chiral chloro substituted isobenzofuran-1（3 H）-imine derivatives were obtained in good yields（up to 85%） and enantioselectivities（up to 70% ee）.
基金National Natural Science Foundation of China (Projects 30772627)a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions, China
文摘Bis{2-[（2,4-dichloro-phenytimino）-methyl]-4,6-diiodo-phenol}-copper（II） （1） has been synthesized and its structure determined by X-ray diffraction. It crystallizes in the monoclinic system, space group P21/n with a = 14.7558（17）, b = 20.770（2）, c = 20.3260（19） A, β = 90.6110（10）°, V= 6229.2（11） A3 and Z = 8. The Cu atom is surrounded by two O atoms and two N atoms from two 2-[（2,4-diehloro-phenylimino）-methyl]-4,6-diiodo-phenol molecules to form a tetrahedral coordination environment. The complex is linked into a column by weak intermolecular interactions.
文摘The amide herbicide has been studied systematically in our laboratory for many years. We have synthesized 74 kinds of amide-compounds, most of which are aliphatic amides and the others are furfural and aromatic amides. It has been found that the N-3′, 4′-dichloro-α-methyl-propionanilide (DCMPA) behaves as effective as N-3.4-dichloro-
文摘Condensation of D-glucose, o-phenylenediamine and N,N-benzylphenylhydrazine hydrochloride (NNBPHH) in a one-pot reaction, or condensation of 2-(D-arabino-tetritol-1-yl) quinoxaline and NNBPHH, gave 3-(D-erythro-glycerol-1- yl)-1-phenyl-1H-pyrazolo[3,4-b]quinoxaline. The structure of the latter was determined by 1H NMR spectroscopy and by synthesis using phenylhydrazine hydrochloride instead of NNBPHH. Condensation of D-glucose and 4,5-dichloro-o-phenylenediamine gave 6,7-dichloro-2-(D-arabino-tetritol-1-yl)quinoxaline, which upon condensation with NNBPHH gave the corresponding 6,7-dichloro-3-(D-erythro-glycerol-1-yl)-1-phenyl-1H-pyrazolo[3,4-b]quinoxaline. The structure and mechanism of formation of these compounds are discussed.
基金support from the Post-doctoral Foundation Project of Tangshan Normal University(no.2018A03)the National Natural Science Foundation of China(no.21771141).
文摘A 24-metal Cd_((II))-Sm_((III))nanocluster[Cd_(18)Sm_(6)L_(9)(OAc)_(3)_(6)](CSN)was constructed from a new flexible Schiff base ligand.It can be used as a probe to detect 2,6-dichloro-4-nitroaniline(DCN,LOD:0.67-0.75μM),which is not influenced by the presence of other pesticides.The response behavior of CSN to DCN is expressed using a first-order equation 1/I_(475nm)+1/I_(645nm)+1/I_(945nm)=A[DCN]+B,and it is used to determine DCN concentrations in the extract of fruits.For example,for the concentration determination of DCN in carrot extract,the ranges of recovery and RSD are 96.11-103.50%and 0.95-4.12%,respectively.
文摘As a good antimicrobial active ingredient, 2,4,4′ trichloro 2′ hydroxydiphenyl ether has been already commercially available since 1970s. For this paper halogenated hydroxydiphenyl ethers were prepared and purified, and their analytical conditions by HPLC were studied. Further purification of 2,4,4′ trichloro 2′ hydroxydiphenyl ether was also studied. The adsorption ability of different decolourants, e.g. alumina and bentonite, for each component in crude product of 2,4,4′ trichloro 2′ hydroxydiphenyl ether was varied. 2,4,4′ trichloro 2′ hydroxydiphenyl ether might be adsorbed by active carbon. The colored impurities might be adsorbed by alumina. The colorless impurities might be adsorbed by bentonite.
