Real-time monitoring of physiological signals on human skin surfaces represents a core functionality of wearable medical devices.Although microfluidic technology has garnered considerable attention in biochemical sens...Real-time monitoring of physiological signals on human skin surfaces represents a core functionality of wearable medical devices.Although microfluidic technology has garnered considerable attention in biochemical sensing(e.g.,sweat,glucose),its potential for physiological mechanosensing remains largely untapped,hindering multi-parameter integration in one platform.Herein,we introduce a dualmode flexible physiological force sensor based on microfluidic deformation.This sensor integrates capacitive and triboelectric mechanisms,overcoming single-mode sensing limitations.The liquid droplet serves a dual role:it acts as a deformable electrode,forming a capacitive structure with the bottom electrode for static force detection,while functioning as a triboelectric component interacting with the PDMS tribo-layer to capture dynamic force signals.Through parameter optimization,the sensor achieves synergistic optimization between sensitivity(4.078 kPa^(-1))and detection range,with dynamic response of 21 ms.Experimental validation demonstrated 168-hours stable underwater pulse monitoring,confirming its biomedical potential for mechanical-biochemical signal fusion and holistic physiaological analysis.展开更多
基金supported by the National Key Research and Development Program(2021YFA1201602),the NSFC(T2422003,52302219)the Fundamental Research Funds for the Central Universities(Grant No.2024CDTZCQ-012,2024CDJGF-031)。
文摘Real-time monitoring of physiological signals on human skin surfaces represents a core functionality of wearable medical devices.Although microfluidic technology has garnered considerable attention in biochemical sensing(e.g.,sweat,glucose),its potential for physiological mechanosensing remains largely untapped,hindering multi-parameter integration in one platform.Herein,we introduce a dualmode flexible physiological force sensor based on microfluidic deformation.This sensor integrates capacitive and triboelectric mechanisms,overcoming single-mode sensing limitations.The liquid droplet serves a dual role:it acts as a deformable electrode,forming a capacitive structure with the bottom electrode for static force detection,while functioning as a triboelectric component interacting with the PDMS tribo-layer to capture dynamic force signals.Through parameter optimization,the sensor achieves synergistic optimization between sensitivity(4.078 kPa^(-1))and detection range,with dynamic response of 21 ms.Experimental validation demonstrated 168-hours stable underwater pulse monitoring,confirming its biomedical potential for mechanical-biochemical signal fusion and holistic physiaological analysis.
