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Research Methods for“Dose-Effect-Toxicity”Relationship of Chinese Medicine Herbs
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作者 ZUO Qian YAN Fei +4 位作者 CUI Dong-xiao ZHAO Ying FU Rui-ja XU Ding-qiao TANG Yu-ping 《Chinese Journal of Integrative Medicine》 2025年第8期760-767,共8页
Chinese medicinal herb(CMH)has the characteristics of"multiple components,multiple pathways,and multiple targets."As a key part of the CMH system,CMH has rapidly expanded globally through research in clinica... Chinese medicinal herb(CMH)has the characteristics of"multiple components,multiple pathways,and multiple targets."As a key part of the CMH system,CMH has rapidly expanded globally through research in clinical trials,pharmacology,mechanisms,and new drug development,along with its significant therapeutic effects.(1)However,in 2018-2020,the proportion of adverse drug reactions/events reported in CMH was approximately 13.6%,which poses a great challenge to the research and development of new CMH and the safe use of medicines in the clinic,hindering the development of CMH. 展开更多
关键词 clinical trials multiple components adverse drug reactions dose effect toxicity multiple targets chinese medicinal herb cmh Chinese medicine herbs new drug developmentalong
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