Dance video is an innovative form that integrates dance art with imaging technology,enriching the expression of dance through techniques such as photography,videography,and special effects.This paper explores the defi...Dance video is an innovative form that integrates dance art with imaging technology,enriching the expression of dance through techniques such as photography,videography,and special effects.This paper explores the definition,current development,artistic expression,social impact,and future trends of dance video.Through narrative construction,visual impact,emotional resonance,technological innovation,and cultural expression,dance video enhances the narrative and visual appeal of dance.In the future,dance video will focus more on the integration of virtual reality(VR)and augmented reality(AR)technologies.However,it also faces challenges such as rapid technological updates,maintaining artistic originality,and balancing commercial interests.展开更多
This article aims to provide a comprehensive analysis of the role and development prospects of direct satellite-to-phone technology in the global communication landscape.It explores the importance,current development ...This article aims to provide a comprehensive analysis of the role and development prospects of direct satellite-to-phone technology in the global communication landscape.It explores the importance,current development status,key technical challenges,future directions,and countermeasures of this technology from multiple dimensions.The article explains the significance and necessity of direct satellite-to-phone technology in the global communication field,discusses its development background and importance as one of the key technologies in the 6G era,and outlines the research objectives,methodology,and structure of the paper.Additionally,the article reviews and analyzes the development history of direct satellite-to-phone technology on a global scale,discusses the key technical points in achieving this technology,and predicts its potential role and development direction in future communication systems from the perspective of 6G network architecture.It also explores new application scenarios and service models that may emerge from technological advancements,as well as their impact on future communication networks.The development history of direct satellite-to-phone technology and its role in current and future communication networks are emphasized,highlighting its value in promoting global communication infrastructure construction.The article also proposes improvement suggestions for existing issues and points out future research directions.展开更多
In recent years,with the rapid development of next-generation digital technologies,the vigorous growth of the digital economy,and the continuous deepening of the strategy to build a strong education nation,the digital...In recent years,with the rapid development of next-generation digital technologies,the vigorous growth of the digital economy,and the continuous deepening of the strategy to build a strong education nation,the digital transformation of vocational education has increasingly become a focal point.This trend has prompted researchers to delve into the background of digital transformation in vocational education,the current challenges and difficulties it faces,and actively seek effective pathways to enhance vocational education quality through digital transformation.It also explores how to better leverage the potential of digital technologies in educational services.Against this backdrop,this paper employs CiteSpace software to conduct a visual analysis of research literature related to digital transformation and vocational education,aiming to outline the research hotspots and evolutionary trends in this field.Based on the analysis results,the paper further proposes constructive suggestions and prospects for the future development direction of vocational education digital transformation.展开更多
In the global wave of energy transition and low-carbon development,China Petroleum Enterprise Association,together with the University of International Business and Economics,China University of Petroleum-Beijing,Sout...In the global wave of energy transition and low-carbon development,China Petroleum Enterprise Association,together with the University of International Business and Economics,China University of Petroleum-Beijing,Southwest Petroleum University,and other institutions,released four significant blue books on April 17:Annual Operating Report of China’s Natural Gas Industry Blue Book(2024-2025),China Oil&Gas Industry Development Analysis and Outlook Blue Book(2024-2025),China Low-Carbon Economy Development Report Blue Book(2024-2025),and Refined Oil and New Energy Development Report Blue Book(2024-2025).This series of blue books provides a comprehensive and high-level analysis of the development,issues,and trends in the oil and gas industry,offering a detailed depiction of the China Oil&Gas industry and its progress towards low-carbon development.展开更多
On August 24,2020,General Secretary Xi Jinping,for the first time,raised the idea that“the world has entered a period of turbulence and change”at a symposium with experts in the economic and social fields.The report...On August 24,2020,General Secretary Xi Jinping,for the first time,raised the idea that“the world has entered a period of turbulence and change”at a symposium with experts in the economic and social fields.The report to the 20th National Congress of the Communist Party of China(CPC)further elaborated on the notion that“the world has entered a new period of turbulence and change”.展开更多
Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proo...Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article.展开更多
China is carving out a distinctive development path which features urban-rural integration.This approach has not only yielded tangible results domestically but also drawn the attention of other countries.
Since 2011,America has maintained its position as the world’s largest natural gas producer.Since 2017,America has consistently experienced a surplus in natural gas supply,becoming a net exporter of natural gas.Americ...Since 2011,America has maintained its position as the world’s largest natural gas producer.Since 2017,America has consistently experienced a surplus in natural gas supply,becoming a net exporter of natural gas.America’s“natural gas independence”has reshaped the global natural gas market,creating a new pattern of“supply shifting westward and consumption shifting eastward”.展开更多
China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have alwa...China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have always been a priority in national development.At its fourth plenary session held in October 2025,the 20th Central Committee of the Communist Party of China(CPC)once again emphasized the need to accelerate agricultural and rural modernization,and advance all-around rural revitalization over the next five years.展开更多
Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables th...Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables this dynamic is the white matter(WM),known to be affected in neurodevelopmental disorders(NDDs)(Rokach et al.,2024).WM formation is mediated by myelination,a multifactorial process driven by neuro-glia interactions dependent on proper neuronal functionality(Simons and Trajkovic,2006).Another key aspect of neurodevelopmental abnormalities involves neuronal dynamics and function,with recent advances significantly enhancing our understanding of both neuronal and glial mitochondrial function(Devine and Kittler,2018;Rojas-Charry et al.,2021).Energy homeostasis in neurons,attributed largely to mitochondrial function,is critical for proper functionality and interactions with oligodendrocytes(OLs),the cells forming myelin in the brain’s WM.We herein discuss the interplay between these processes and speculate on potential dysfunction in NDDs.展开更多
AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 ...AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 and 2022,were retrieved from the Web of Science Core Collection.Bibliometric analyses were performed using VOSviewer and CiteSpace software to explore publication trends,as well as the contributions and collaborative networks of countries/regions,authors,institutions,and journals.RESULTS:The annual number of publications on strabismus showed a consistent upward trend.The United States(USA)maintained a leading position in this research field while Republic of Korea and China emerged as rapidly advancing contributors over the last decade.The University of California,Los Angeles ranked as the most productive institution,and Jonathan M.Holmes from USA was the most productive author.Journal of AAPOS was the leading journal with the most strabismus publications,whereas the two most highly cited articles were both published in Ophthalmology.Co-occurrence analysis identified pivotal keywords and burst terms,including intermittent exotropia(IXT),acute acquired comitant esotropia(AACE),functional magnetic resonance imaging(fMRI),and surgical treatment,which were confirmed as predominant and frontier topics.CONCLUSION:This study provides a comprehensive bibliometric analysis of strabismus research,revealing the evolution of research hotspots over the past 30y and outlining several cutting-edge directions for future investigation.展开更多
Governance debates gained strong momentum in Africa in early December 2025 as the China-Kenya Readers Forum on Xi Jinping:The Governance of China convened in Nairobi on 1 December 2025,followed by a promotional event ...Governance debates gained strong momentum in Africa in early December 2025 as the China-Kenya Readers Forum on Xi Jinping:The Governance of China convened in Nairobi on 1 December 2025,followed by a promotional event for the English edition of the book’s fifth volume on 3 December 2025 in Johannesburg,South Africa.展开更多
This study examines the methods to plan the development of offshore oilfields over the years,which are used to support the decision-making on the development of offshore oilfields.About 100 papers are analysed and cat...This study examines the methods to plan the development of offshore oilfields over the years,which are used to support the decision-making on the development of offshore oilfields.About 100 papers are analysed and categorised into different groups of main early-stage decisions.The present study stands in contrast to the contributions of the operations research and system engineering review articles,on the one hand,and the petroleum engineering review articles,on the other.This is because it does not focus on one methodological approach,nor does it limit the literature analysis by offshore oilfield characteristics.Consequently,the present analysis may offer valuable insights,for instance,by identifying environmental planning decisions as a recent yet highly significant concern that is currently being imposed on decision-making process.Thus,it is evident that the incorporation of safety criteria within the technical-economic decision-making process for the design of production systems would be a crucial requirement at development phase.展开更多
The mechanistic target of rapamycin(m TOR) is a serine/threonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regul...The mechanistic target of rapamycin(m TOR) is a serine/threonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regulates diverse aspects of neural development and function. Genetic mutations within the m TOR pathway lead to severe neurodevelopmental disorders, collectively known as “mTORopathies”(Crino, 2020). Dysfunctions of m TOR, including both its hyperactivation and hypoactivation, have also been implicated in a wide spectrum of other neurodevelopmental and neurodegenerative conditions, highlighting its importance in CNS health.展开更多
Motor neuron diseases are sporadic or inherited fatal neurodegenerative conditions.They selectively affect the upper and/or lower motor neurons in the brain and spinal cord and feature a slow onset and a subacute cour...Motor neuron diseases are sporadic or inherited fatal neurodegenerative conditions.They selectively affect the upper and/or lower motor neurons in the brain and spinal cord and feature a slow onset and a subacute course contingent upon the site of damage.The main types include amyotrophic lateral sclerosis,progressive muscular atrophy,primary lateral sclerosis,and progressive bulbar palsy,the pathological processes of which are largely identical,with the main disparity lying in the location of the lesions.Amyotrophic lateral sclerosis is the representative condition in this group of diseases,while other types are its variants.Hence,this article mainly focuses on the advancements and challenges in drug research for amyotrophic lateral sclerosis but also briefly addresses several other important degenerative motor neuron diseases.Although the precise pathogenesis remains elusive,recent advancements have shed light on various theories,including gene mutation,excitatory amino acid toxicity,autoimmunology,and neurotrophic factors.The US Food and Drug Administration has approved four drugs for use in delaying the progression of amyotrophic lateral sclerosis:riluzole,edaravone,AMX0035,and tofersen,with the latter being the most recent to receive approval.However,following several phaseⅢtrials that failed to yield favorable outcomes,AMX0035 has been voluntarily withdrawn from both the US and Canadian markets.This article presents a comprehensive summary of drug trials primarily completed between January 1,2023,and June 30,2024,based on data sourced from clinicaltrials.gov.Among these trials,five are currently in phaseⅠ,seventeen are in phaseⅡ,and eleven are undergoing phaseⅢevaluation.Notably,24 clinical trials are now investigating potential disease-modifying therapy drugs,accounting for the majority of the drugs included in this review.Some promising drugs being investigated in preclinical studies,such as ATH-1105,are included in our analysis,and another review in frontiers in gene therapy and immunotherapy has demonstrated their therapeutic potential for motor neuron diseases.This article was written to be an overview of research trends and treatment prospects related to motor neuron disease drugs,with the aim of highlighting the latest potentialities for clinical therapy.展开更多
Oligodendrocytes and their cell-intrinsic gene regulatory network:Oligodendrocytes(OLs)are the myelinating glial cells of the vertebrate central nervous system.They are responsible for insulating neuronal axons with a...Oligodendrocytes and their cell-intrinsic gene regulatory network:Oligodendrocytes(OLs)are the myelinating glial cells of the vertebrate central nervous system.They are responsible for insulating neuronal axons with a lipid-rich myelin sheath,which enables the saltatory conduction of action potentials.During development,oligodendrocyte progenitor cells(OPCs)emerge from neural stem cells in the ventricular zone.They then proliferate,increase their number,and migrate to their final destination where they encounter unmyelinated neuronal axons and differentiate in a stepwise fashion into myelinating oligodendrocytes(mOLs)under the influence of environmental stimuli.展开更多
Modern hydrometallurgy has been developing for more than 100 years and the related articles keep piling up.Based on a bibliometric analysis of the articles in Hydrometallurgy,the most authoritative journal in the fiel...Modern hydrometallurgy has been developing for more than 100 years and the related articles keep piling up.Based on a bibliometric analysis of the articles in Hydrometallurgy,the most authoritative journal in the field of hydrometallurgy,we try to catch the research and development trends from a global perspective.Firstly,keywords burstness shows that rare earth,recycling,lithium,ionic liquid,and thorium are the hotspots in recent years,and the economic and technological reasons behind them were discussed in depth.Secondly,the proportion of biohydrometallurgy grows fast from 5%to 13%and the related articles are almost all about bioleaching.There are some new directions such as direct preparation of materials in hydrometallurgical processes and ion-imprinted techniques.Thirdly,the advanced instrument analysis methods such as XAFS(X-ray absorption fine structure),gene sequencing,and micro-CT promote the deep understanding of hydrometallurgy mechanism.Finally,the cooperation network and contribution of the main institutes were mapped.展开更多
Chinese steel industry has made significant progress on reducing fresh water consumption and CO_2/SO_2/COD（ chemical oxygen demand） /dust emissions,and improving comprehensive utilization of solid waste. Some steel ...Chinese steel industry has made significant progress on reducing fresh water consumption and CO_2/SO_2/COD（ chemical oxygen demand） /dust emissions,and improving comprehensive utilization of solid waste. Some steel companies have become topped worldwide. However,due to the large output quantity of crude steel,the whole steel industry is still a huge source of pollutants. At present,environmental protection standards are encountering challenges of lack of technical support,taxation policy and other issues. Steel industry is currently facing enormous environmental pressure. The development trends of environmental protection technologies were studied by summarizing different development stages. To realize the development targets,the industry needs to carry out its research with independent intellectual property rights,develop comprehensive management systems and establish ecological chain with other industries. This can not only raise the level of environmental protection in a broader range,but also improve the energy efficiency of iron and steel plants and increase added value of waste utilization. Finally,23 environmental protection technologies were proposed and 4 new environmental protection practices were studied.展开更多
We aim to present an overview of the status of adhesives in the wood industry, especially in the area of wood-based panels. The review summarizes the current state of research of two kinds of adhesives, i.e., syntheti...We aim to present an overview of the status of adhesives in the wood industry, especially in the area of wood-based panels. The review summarizes the current state of research of two kinds of adhesives, i.e., synthetic adhesives and natural adhesives. Synthetic adhesives, consisting of urea-formaldehyde resins （UF）, phenol-formaldehyde resins （PF）, polyvinyl acetate emulsion （PVAc） and isocyanates, are widely used. For UF, most investigations are concerned with the reduction of free formaldehyde; for PF, most studies focus on finding new chemicals to replace phenol. PVAc has poor properties, but these can be improved by a blending reactions and copolymerization with other chemicals. Isocyanate is an environmentally friendly synthetic adhesive, but also suffers from inadequate properties. Natural adhesives, such as protein/starch, lignin and tannins, have poor bonding effect that limits their level of use, but their main advantages are that they are environmentally friendly and a renewable resource. Studies of modification can improve the bonding performances and gradually cause natural adhesives to become applied in industrial production. Some proposals for future development and the importance of environmentally friendly adhesives are provided, which will be helpful in future theoretical and experimental research.展开更多
The major contemporary in road pavement engineering is related to the creation of green and sustainable infrastructures,e.g.,reduction of environmental impacts,increase in traffic safety,and transportation efficiency,...The major contemporary in road pavement engineering is related to the creation of green and sustainable infrastructures,e.g.,reduction of environmental impacts,increase in traffic safety,and transportation efficiency,etc.This review presents the recent trends in research and the technical solutions developed so far to address these challenges.After the analysis of research status in the past decades,a novel technology system of eco-friendly pavements is proposed considering two solutions,materials modification and structure improvement.The construction of an eco-friendly pavement can be achieved thanks to several different technologies ensuring permeable,noise-reducing,self-luminous,and exhaust-decomposing properties as well as apporting lower heat absorbing and enhanced anti-/de-icing characteristics.A systematic review of these technologies is presented pivoting on four main aspects:technical principle,material and structural composition,performance evaluation,and engineering application.The current trend in road engineering is combining the pavement infrastructure with various eco-friendly functions,e.g.,water permeability,noise reduction,low heat absorption,exhaust gas decomposition,and anti-/de-icing.Finally,the review lists the drawbacks of the existing technologies,including high cost,single function,etc.,and depicts the future developing direction and architecture of the next generation of eco-friendly pavements in which the road infrastructure should have more environmentally friendly functions than the existing technology.展开更多
基金National Social Science Fund of the Chongqing,China(Grant No.2023PY86)。
文摘Dance video is an innovative form that integrates dance art with imaging technology,enriching the expression of dance through techniques such as photography,videography,and special effects.This paper explores the definition,current development,artistic expression,social impact,and future trends of dance video.Through narrative construction,visual impact,emotional resonance,technological innovation,and cultural expression,dance video enhances the narrative and visual appeal of dance.In the future,dance video will focus more on the integration of virtual reality(VR)and augmented reality(AR)technologies.However,it also faces challenges such as rapid technological updates,maintaining artistic originality,and balancing commercial interests.
文摘This article aims to provide a comprehensive analysis of the role and development prospects of direct satellite-to-phone technology in the global communication landscape.It explores the importance,current development status,key technical challenges,future directions,and countermeasures of this technology from multiple dimensions.The article explains the significance and necessity of direct satellite-to-phone technology in the global communication field,discusses its development background and importance as one of the key technologies in the 6G era,and outlines the research objectives,methodology,and structure of the paper.Additionally,the article reviews and analyzes the development history of direct satellite-to-phone technology on a global scale,discusses the key technical points in achieving this technology,and predicts its potential role and development direction in future communication systems from the perspective of 6G network architecture.It also explores new application scenarios and service models that may emerge from technological advancements,as well as their impact on future communication networks.The development history of direct satellite-to-phone technology and its role in current and future communication networks are emphasized,highlighting its value in promoting global communication infrastructure construction.The article also proposes improvement suggestions for existing issues and points out future research directions.
基金a phased achievement of the Modern Animal Husbandry Professional Group of Guangxi Agricultural Vocational University of Technology-a high-level professional group under the second round of the“Double High-Level Plan”in the Guangxi Zhuang Autonomous Region2025 university-level teaching research and reform project titled“Study on the Content,Carriers and Cultivation Mechanism of College Counselors’Artificial Intelligence Literacy from the Perspective of New-Quality Ideological and Political Competence”(XJG2552)2022 University-level Project of Humanities,Philosophy and Social Sciences Research,Guangxi Agricultural Vocational and Technical University:Exploration and Practice on the Construction of Counselor Performance Appraisal System in Vocational Undergraduate Colleges(YZS2213).
文摘In recent years,with the rapid development of next-generation digital technologies,the vigorous growth of the digital economy,and the continuous deepening of the strategy to build a strong education nation,the digital transformation of vocational education has increasingly become a focal point.This trend has prompted researchers to delve into the background of digital transformation in vocational education,the current challenges and difficulties it faces,and actively seek effective pathways to enhance vocational education quality through digital transformation.It also explores how to better leverage the potential of digital technologies in educational services.Against this backdrop,this paper employs CiteSpace software to conduct a visual analysis of research literature related to digital transformation and vocational education,aiming to outline the research hotspots and evolutionary trends in this field.Based on the analysis results,the paper further proposes constructive suggestions and prospects for the future development direction of vocational education digital transformation.
文摘In the global wave of energy transition and low-carbon development,China Petroleum Enterprise Association,together with the University of International Business and Economics,China University of Petroleum-Beijing,Southwest Petroleum University,and other institutions,released four significant blue books on April 17:Annual Operating Report of China’s Natural Gas Industry Blue Book(2024-2025),China Oil&Gas Industry Development Analysis and Outlook Blue Book(2024-2025),China Low-Carbon Economy Development Report Blue Book(2024-2025),and Refined Oil and New Energy Development Report Blue Book(2024-2025).This series of blue books provides a comprehensive and high-level analysis of the development,issues,and trends in the oil and gas industry,offering a detailed depiction of the China Oil&Gas industry and its progress towards low-carbon development.
文摘On August 24,2020,General Secretary Xi Jinping,for the first time,raised the idea that“the world has entered a period of turbulence and change”at a symposium with experts in the economic and social fields.The report to the 20th National Congress of the Communist Party of China(CPC)further elaborated on the notion that“the world has entered a new period of turbulence and change”.
文摘Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article.
文摘China is carving out a distinctive development path which features urban-rural integration.This approach has not only yielded tangible results domestically but also drawn the attention of other countries.
文摘Since 2011,America has maintained its position as the world’s largest natural gas producer.Since 2017,America has consistently experienced a surplus in natural gas supply,becoming a net exporter of natural gas.America’s“natural gas independence”has reshaped the global natural gas market,creating a new pattern of“supply shifting westward and consumption shifting eastward”.
文摘China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have always been a priority in national development.At its fourth plenary session held in October 2025,the 20th Central Committee of the Communist Party of China(CPC)once again emphasized the need to accelerate agricultural and rural modernization,and advance all-around rural revitalization over the next five years.
文摘Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables this dynamic is the white matter(WM),known to be affected in neurodevelopmental disorders(NDDs)(Rokach et al.,2024).WM formation is mediated by myelination,a multifactorial process driven by neuro-glia interactions dependent on proper neuronal functionality(Simons and Trajkovic,2006).Another key aspect of neurodevelopmental abnormalities involves neuronal dynamics and function,with recent advances significantly enhancing our understanding of both neuronal and glial mitochondrial function(Devine and Kittler,2018;Rojas-Charry et al.,2021).Energy homeostasis in neurons,attributed largely to mitochondrial function,is critical for proper functionality and interactions with oligodendrocytes(OLs),the cells forming myelin in the brain’s WM.We herein discuss the interplay between these processes and speculate on potential dysfunction in NDDs.
基金Supported by National Natural Science Foundation of China(No.82020108006,No.81730025).
文摘AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 and 2022,were retrieved from the Web of Science Core Collection.Bibliometric analyses were performed using VOSviewer and CiteSpace software to explore publication trends,as well as the contributions and collaborative networks of countries/regions,authors,institutions,and journals.RESULTS:The annual number of publications on strabismus showed a consistent upward trend.The United States(USA)maintained a leading position in this research field while Republic of Korea and China emerged as rapidly advancing contributors over the last decade.The University of California,Los Angeles ranked as the most productive institution,and Jonathan M.Holmes from USA was the most productive author.Journal of AAPOS was the leading journal with the most strabismus publications,whereas the two most highly cited articles were both published in Ophthalmology.Co-occurrence analysis identified pivotal keywords and burst terms,including intermittent exotropia(IXT),acute acquired comitant esotropia(AACE),functional magnetic resonance imaging(fMRI),and surgical treatment,which were confirmed as predominant and frontier topics.CONCLUSION:This study provides a comprehensive bibliometric analysis of strabismus research,revealing the evolution of research hotspots over the past 30y and outlining several cutting-edge directions for future investigation.
文摘Governance debates gained strong momentum in Africa in early December 2025 as the China-Kenya Readers Forum on Xi Jinping:The Governance of China convened in Nairobi on 1 December 2025,followed by a promotional event for the English edition of the book’s fifth volume on 3 December 2025 in Johannesburg,South Africa.
基金the Strategic Research Plan of the Centre for Marine Technology and Ocean Engineering(CENTEC),which is financed by the Portuguese Foundation for Science and Technology(Fundação para a Ciência e a Tecnologia FCT)under contract UIDB/UIDP/00134/2020.
文摘This study examines the methods to plan the development of offshore oilfields over the years,which are used to support the decision-making on the development of offshore oilfields.About 100 papers are analysed and categorised into different groups of main early-stage decisions.The present study stands in contrast to the contributions of the operations research and system engineering review articles,on the one hand,and the petroleum engineering review articles,on the other.This is because it does not focus on one methodological approach,nor does it limit the literature analysis by offshore oilfield characteristics.Consequently,the present analysis may offer valuable insights,for instance,by identifying environmental planning decisions as a recent yet highly significant concern that is currently being imposed on decision-making process.Thus,it is evident that the incorporation of safety criteria within the technical-economic decision-making process for the design of production systems would be a crucial requirement at development phase.
基金supported by grants from Simons Foundation (SFARI 479754),CIHR (PJT-180565)the Scottish Rite Charitable Foundation of Canada (to YL)funding from the Canada Research Chairs program。
文摘The mechanistic target of rapamycin(m TOR) is a serine/threonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regulates diverse aspects of neural development and function. Genetic mutations within the m TOR pathway lead to severe neurodevelopmental disorders, collectively known as “mTORopathies”(Crino, 2020). Dysfunctions of m TOR, including both its hyperactivation and hypoactivation, have also been implicated in a wide spectrum of other neurodevelopmental and neurodegenerative conditions, highlighting its importance in CNS health.
基金supported by the National Key Research and Development Program of China,No.2022YFC2703101(to YC)the National Natural Science Fundation of China,No.82371422(to YC)+1 种基金the National Innovation and Entrepreneurship Training Program for College Students,No.202310611408(to XW)the 1·3·5 Project for Disciplines of Excellence Clinical Research Fund,West China Hospital,Sichuan University,No.2023HXFH032(to YC)。
文摘Motor neuron diseases are sporadic or inherited fatal neurodegenerative conditions.They selectively affect the upper and/or lower motor neurons in the brain and spinal cord and feature a slow onset and a subacute course contingent upon the site of damage.The main types include amyotrophic lateral sclerosis,progressive muscular atrophy,primary lateral sclerosis,and progressive bulbar palsy,the pathological processes of which are largely identical,with the main disparity lying in the location of the lesions.Amyotrophic lateral sclerosis is the representative condition in this group of diseases,while other types are its variants.Hence,this article mainly focuses on the advancements and challenges in drug research for amyotrophic lateral sclerosis but also briefly addresses several other important degenerative motor neuron diseases.Although the precise pathogenesis remains elusive,recent advancements have shed light on various theories,including gene mutation,excitatory amino acid toxicity,autoimmunology,and neurotrophic factors.The US Food and Drug Administration has approved four drugs for use in delaying the progression of amyotrophic lateral sclerosis:riluzole,edaravone,AMX0035,and tofersen,with the latter being the most recent to receive approval.However,following several phaseⅢtrials that failed to yield favorable outcomes,AMX0035 has been voluntarily withdrawn from both the US and Canadian markets.This article presents a comprehensive summary of drug trials primarily completed between January 1,2023,and June 30,2024,based on data sourced from clinicaltrials.gov.Among these trials,five are currently in phaseⅠ,seventeen are in phaseⅡ,and eleven are undergoing phaseⅢevaluation.Notably,24 clinical trials are now investigating potential disease-modifying therapy drugs,accounting for the majority of the drugs included in this review.Some promising drugs being investigated in preclinical studies,such as ATH-1105,are included in our analysis,and another review in frontiers in gene therapy and immunotherapy has demonstrated their therapeutic potential for motor neuron diseases.This article was written to be an overview of research trends and treatment prospects related to motor neuron disease drugs,with the aim of highlighting the latest potentialities for clinical therapy.
基金supported by grants from the Deutsche Forschungsgemeinschaft(DFG)to MW.
文摘Oligodendrocytes and their cell-intrinsic gene regulatory network:Oligodendrocytes(OLs)are the myelinating glial cells of the vertebrate central nervous system.They are responsible for insulating neuronal axons with a lipid-rich myelin sheath,which enables the saltatory conduction of action potentials.During development,oligodendrocyte progenitor cells(OPCs)emerge from neural stem cells in the ventricular zone.They then proliferate,increase their number,and migrate to their final destination where they encounter unmyelinated neuronal axons and differentiate in a stepwise fashion into myelinating oligodendrocytes(mOLs)under the influence of environmental stimuli.
基金Project(2019JJ40377)supported by the Natural Science Foundation of Hunan Province,ChinaProject(2020CX026)supported by the Innovation-Driven Project of Central South University,ChinaProject(51934010)supported by the Major Program of National Natural Science Foundation of China。
文摘Modern hydrometallurgy has been developing for more than 100 years and the related articles keep piling up.Based on a bibliometric analysis of the articles in Hydrometallurgy,the most authoritative journal in the field of hydrometallurgy,we try to catch the research and development trends from a global perspective.Firstly,keywords burstness shows that rare earth,recycling,lithium,ionic liquid,and thorium are the hotspots in recent years,and the economic and technological reasons behind them were discussed in depth.Secondly,the proportion of biohydrometallurgy grows fast from 5%to 13%and the related articles are almost all about bioleaching.There are some new directions such as direct preparation of materials in hydrometallurgical processes and ion-imprinted techniques.Thirdly,the advanced instrument analysis methods such as XAFS(X-ray absorption fine structure),gene sequencing,and micro-CT promote the deep understanding of hydrometallurgy mechanism.Finally,the cooperation network and contribution of the main institutes were mapped.
基金supported by National Natural Science Foundation of China(Grants No.51234003)
文摘Chinese steel industry has made significant progress on reducing fresh water consumption and CO_2/SO_2/COD（ chemical oxygen demand） /dust emissions,and improving comprehensive utilization of solid waste. Some steel companies have become topped worldwide. However,due to the large output quantity of crude steel,the whole steel industry is still a huge source of pollutants. At present,environmental protection standards are encountering challenges of lack of technical support,taxation policy and other issues. Steel industry is currently facing enormous environmental pressure. The development trends of environmental protection technologies were studied by summarizing different development stages. To realize the development targets,the industry needs to carry out its research with independent intellectual property rights,develop comprehensive management systems and establish ecological chain with other industries. This can not only raise the level of environmental protection in a broader range,but also improve the energy efficiency of iron and steel plants and increase added value of waste utilization. Finally,23 environmental protection technologies were proposed and 4 new environmental protection practices were studied.
基金supported by the Teaching Reform Key Research Project of Beijing Forestry University, China (No. BJFU2010JG014)
文摘We aim to present an overview of the status of adhesives in the wood industry, especially in the area of wood-based panels. The review summarizes the current state of research of two kinds of adhesives, i.e., synthetic adhesives and natural adhesives. Synthetic adhesives, consisting of urea-formaldehyde resins （UF）, phenol-formaldehyde resins （PF）, polyvinyl acetate emulsion （PVAc） and isocyanates, are widely used. For UF, most investigations are concerned with the reduction of free formaldehyde; for PF, most studies focus on finding new chemicals to replace phenol. PVAc has poor properties, but these can be improved by a blending reactions and copolymerization with other chemicals. Isocyanate is an environmentally friendly synthetic adhesive, but also suffers from inadequate properties. Natural adhesives, such as protein/starch, lignin and tannins, have poor bonding effect that limits their level of use, but their main advantages are that they are environmentally friendly and a renewable resource. Studies of modification can improve the bonding performances and gradually cause natural adhesives to become applied in industrial production. Some proposals for future development and the importance of environmentally friendly adhesives are provided, which will be helpful in future theoretical and experimental research.
基金This paper was financially supported by the National Natural Science Foundation of China(52038001,52122809,51908058).
文摘The major contemporary in road pavement engineering is related to the creation of green and sustainable infrastructures,e.g.,reduction of environmental impacts,increase in traffic safety,and transportation efficiency,etc.This review presents the recent trends in research and the technical solutions developed so far to address these challenges.After the analysis of research status in the past decades,a novel technology system of eco-friendly pavements is proposed considering two solutions,materials modification and structure improvement.The construction of an eco-friendly pavement can be achieved thanks to several different technologies ensuring permeable,noise-reducing,self-luminous,and exhaust-decomposing properties as well as apporting lower heat absorbing and enhanced anti-/de-icing characteristics.A systematic review of these technologies is presented pivoting on four main aspects:technical principle,material and structural composition,performance evaluation,and engineering application.The current trend in road engineering is combining the pavement infrastructure with various eco-friendly functions,e.g.,water permeability,noise reduction,low heat absorption,exhaust gas decomposition,and anti-/de-icing.Finally,the review lists the drawbacks of the existing technologies,including high cost,single function,etc.,and depicts the future developing direction and architecture of the next generation of eco-friendly pavements in which the road infrastructure should have more environmentally friendly functions than the existing technology.
