Scientific modeling provides mathematical abstractions of real-world systems and builds software as implementations of these mathematical abstractions.Ocean science is a multidisciplinary discipline developing scienti...Scientific modeling provides mathematical abstractions of real-world systems and builds software as implementations of these mathematical abstractions.Ocean science is a multidisciplinary discipline developing scientific models and simulations as ocean sys-tem models that are an essential research asset.In software engineering and information systems research,modeling is also an essential activity.In particular,business process modeling for business process management and systems engineering is the activity of representing processes of an enterprise,so that the current process may be analyzed,improved and automated.In this paper,we employ process modeling for analyzing sci-entific software development in ocean science to advance the state in engineering of ocean system models and to better understand how ocean system models are developed and maintained in ocean science.We interviewed domain experts in semi-structured inter-views,analyzed the results via thematic analysis,and modeled the results via the Busi-ness Process Modeling Notation(BPMN).The processes modeled as a result describe an aspired state of software development in the domain,which are often not(yet)imple-mented.This enables existing processes in simulation-based system engineering to be improved with the help of these process models.展开更多
Based on the analysis of the development process system status of domestic and foreign civil aircraft airborne system suppliers,this paper proposes the overall construction idea of"a set of civil aircraft process...Based on the analysis of the development process system status of domestic and foreign civil aircraft airborne system suppliers,this paper proposes the overall construction idea of"a set of civil aircraft process system"based on IPD(Integrated product development)in the organization.The development stage,process,activity and task are the logical framework elements of the system construction."Based on process decomposition,vertical stratification,horizontal segmentation,combination of special and common,process customized to tools,role and process integration,giving full consideration to the interface between supplier management and process modules"etc.are the concrete ideas.Moreover,formulate top⁃level system construction standards,implemented by process system management tool platform,so that the process system and development work can be effectively integrated to effectively guide the development work of airborne system suppliers,and meet the quality and airworthiness requirements of civil aircraft development.Through the development application of a certain type of flight control system,the process system and tool platform were verified and optimized in practice.展开更多
The development of women’s higher education in China can be divided into four stages:emergence(1908-1948);foundation(1949-1976);accelerating development(1977-2008);and the qualitative leap(2009-2020).This work consid...The development of women’s higher education in China can be divided into four stages:emergence(1908-1948);foundation(1949-1976);accelerating development(1977-2008);and the qualitative leap(2009-2020).This work considers the principal institutional mechanisms that contributed to this development.First,flexibly planned parenthood gradually promoted gender equality and openness in society facilitated by systematic“awards,grants,and loans”initiatives to support women’s higher education economically.Second,compulsory education ensured that left-out and migrant children had access to higher education.Third,effective connectivity across different education types bridged education gaps between those with different levels of education.Fourth,China made great efforts to invite and integrate international experiences that promoted the development of women’s higher education.Looking beyond these achievements,we also discuss the future trends of women’s higher education in China.展开更多
Dispersed and peripheral spaces in the urban core are influenced both by the trend towards constant growth as well as social ways of life which are constantly evolving. Following a connotation, these two factors there...Dispersed and peripheral spaces in the urban core are influenced both by the trend towards constant growth as well as social ways of life which are constantly evolving. Following a connotation, these two factors therefore play a crucial role in defining the alternation of urban space--in particular, that of the centers. The main focus of this research article is on the methodology used in the survey and evaluation of ＂centralities＂ as well as their developments over the past four decades （1974-2014） in approaches to urban development that has been developed in Graz.~ The analysis has drawn on the four editions （＂evolution＂） of approaches to urban development as conceived by the city of Graz in order to examine their verbal characteristics in regard to centralities. At the same time, the analysis does not examine presentations of plans which exist in supplementary forms （e.g., explanatory reports and supplemented plans）--it restricts itself solely to the various plans set out in the STEKs.2 The highest degree of accuracy has been applied to the notion of ＂centralis＂ in approaches to urban development. The goal of the research project was to depict the modulation of the notion of ＂centrality＂ in the urban context as a space-forming dimension. Furthermore, it clearly shows the extent to which the notion of the ＂centre＂ （in the widest sense of the word） has become distanced from qualitative, spatial development and at the current time of urban development is experiencing a sort of Renaissance. In the field of ＂urban development＂, architectural references in the context of＂centrality＂ have scarcely been researched. This has led to the opening-up of a complex interdisciplinary research field. In order to make the complex architectural determinants of ＂centrality＂ more accessible to the participating disciplines, approaches to urban development have been explored in the form of a social and spatial analysis.展开更多
Vascular stents play an important role in the minimally invasive treatment of vascular diseases,such as vascular stenosis,vascular aneurysm,vascular dissection and vascular atherosclerotic plaque disease.Bare metal st...Vascular stents play an important role in the minimally invasive treatment of vascular diseases,such as vascular stenosis,vascular aneurysm,vascular dissection and vascular atherosclerotic plaque disease.Bare metal stents were initially fabricated;however,the incidence of complications such as thrombosis,inflammation,restenosis,vascular injury,displacement and endoleakage is still high after implantation.To overcome these complications,several strategies for designing functional vascular stents have been carried out.Drug-eluting stents,biodegradable stents and bionic stents were manufactured and investigated.This review aims to comprehensively analyze the vascular diseases suitable for stent implantation treatment,tissue reactions after implantation,the materials and manufacturing techniques used to fabricate vascular stents,the various application scenarios in which they could be used to treat vascular lesions and the development process of vascular stents.Future development trends of vascular stents are expected to prioritize their performance,biocompatibility,and clinical accessibility.The design of vascular stents may be transformed or improved to better fulfill the rehabilitation requirements of vascular disease patients.Finally,various application scenarios may be used to treat vascular or even nonvascular diseases via endovascular access.展开更多
Fischer-Tropsch synthesis(FTS)and hydroformylation are pivotal chemical processes for converting syngas and olefins into valuable hydrocarbons and chemicals.Recent advancements in catalyst design,reaction mechanisms,a...Fischer-Tropsch synthesis(FTS)and hydroformylation are pivotal chemical processes for converting syngas and olefins into valuable hydrocarbons and chemicals.Recent advancements in catalyst design,reaction mechanisms,and process optimization have significantly improved the efficiency,selectivity,and sustainability of these processes.This Account introduces the relevant research activities in the Research Center for Catalysis in Syngas Conversion and Fine Chemicals(DNL0805)of Dalian Institute of Chemical Physics(DICP),Chinese Academy of Sciences.The reactions of interests include FTS,heterogeneous hydroformylation of olefins,alcohol dehydration and oxidation,andα-olefin polymerization,with the emphasis on developing innovative catalysts and processes to address the challenges of traditional processes.Exemplified by the discovery of robust Co-Co_(2)C/AC for FTS and Rh_(1)/POPs-PPh_(3) for heterogeneous hydroformylation of olefins,it demonstrates how lab-scale fundamental understandings on the active sites of catalysts leads to pilot-plant scale-up and finally commercial technologies.Perspectives on the challenges and directions for future developments in these exciting fields are provided.展开更多
The development of chemical technologies,which involves a multistage process covering laboratory research,scale‐up to industrial deployment,and necessitates interdisciplinary collaboration,is often accompanied by sub...The development of chemical technologies,which involves a multistage process covering laboratory research,scale‐up to industrial deployment,and necessitates interdisciplinary collaboration,is often accompanied by substantial time and economic costs.To address these challenges,in this work,we report ChemELLM,a domain‐specific large language model(LLM)with 70 billion parameters for chemical engineering.ChemELLM demonstrates state‐of‐the‐art performance across critical tasks ranging from foundational understanding to professional problem‐solving.It outperforms mainstream LLMs(e.g.,O1‐Preview,GPT‐4o,and DeepSeek‐R1)on ChemEBench,the first multidimensional benchmark for chemical engineering,which encompasses 15 dimensions across 101 distinct essential tasks.To support robust model development,we curated ChemEData,a purpose‐built dataset containing 19 billion tokens for pre‐training and 1 billion tokens for fine‐tuning.This work establishes a new paradigm for artificial intelligence‐driven innovation,bridging the gap between laboratory‐scale innovation and industrial‐scale implementation,thus accelerating technological advancement in chemical engineering.ChemELLM is publicly available at https://chemindustry.iflytek.com/chat.展开更多
China is currently vigorously implementing the“energy conservation and emission reduction”and“dual carbon”strategies.As the most resource-advantaged light metal material in China,Magnesium(Mg)alloy is progressivel...China is currently vigorously implementing the“energy conservation and emission reduction”and“dual carbon”strategies.As the most resource-advantaged light metal material in China,Magnesium(Mg)alloy is progressively expanding its application in automobile,rail transportation,aerospace,medical,and electronic products.Chongqing University,Shanghai Jiaotong University,and Australian National University have conducted extensive research on the preparation,properties,and processes of Mg alloys.In the past 20 years,the proportion of Mg alloy in the automotive industry has gradually expanded,whereas currently the design and development of Mg alloy parts for automobiles has rarely been reported.Thus,the application models and typical parts cases of Mg alloy are summarized mainly from the four systems of the whole vehicle(body system,chassis system,powertrain system,interior,and exterior system).Subsequently,two actual original equipment manufacturers(OEM)cases are used to introduce the development logic of reliable die-cast Mg alloy,including forward design,formability analysis,process design analysis,structural redesign,manufacturing,and testing,aiming to share the methods,processes,and focus of attention of automotive OEMs for developing Mg alloy parts to enhance the confidence and motivation of applying Mg alloy in automotive field.Eventually,the multiple challenges faced by Mg alloy materials are sorted out and how to face these challenges are discussed.National policies and regulations,environmental protection and energy saving,and consumer demand will continue to promote the application of Mg.展开更多
This paper reviewed the trend and development of semi-solid metal technique. The processes and mechanisms for producing slurry of SSM and its industrial applications have been summarized and discussed. Discussions on ...This paper reviewed the trend and development of semi-solid metal technique. The processes and mechanisms for producing slurry of SSM and its industrial applications have been summarized and discussed. Discussions on the basic rheological theory are presented for more applications. Further consideration of the development and application of SSM technique is also proposed.展开更多
This article presents a multiscale simulation approach starting at the molecular level for the adsorption process development. A grand canonical Monte Carlo method is used for the prediction of adsorption isotherms of...This article presents a multiscale simulation approach starting at the molecular level for the adsorption process development. A grand canonical Monte Carlo method is used for the prediction of adsorption isotherms of methanol on an activated carbon at the molecular level. The adsorption isotherms obtained in the linear region （or adsorption constant） are exploited as a model parameter required for the adsorption process simulation. The adsorption process model described by a set of partial differential equations （PDEs） is solved by using the conservation element and solution element method, which produces a fast and an accurate numerical solution to PDEs. The simulation results obtained from the adsorption constant estimated at the molecular level are in good agreement with the experimental results of the pulse response. The systematical multiscale simulation approach addressed in this study may be useful to accelerate the adsorption process development by reducing the number of experiments.展开更多
China is a country abundant in lakes. Lake science development in China, not only aims at the international frontiers of correlative subject development, but also focuses on the national strategic needs in different a...China is a country abundant in lakes. Lake science development in China, not only aims at the international frontiers of correlative subject development, but also focuses on the national strategic needs in different ages. This paper describes the general situation and distribution characteristics of Chinese lakes, systematically reviews development process of Chinese lake science and its progress in lake physics, lake chemistry, lake biology, lake sediment and lake-watershed management, finally looks forward to the developing tendency of Chinese lake science in future.展开更多
China＇s reform and opening-up policy has brought the country a great development opportunity. The high-speed growth of the economy not only led China to a period of industrialization, urbanization, informatization an...China＇s reform and opening-up policy has brought the country a great development opportunity. The high-speed growth of the economy not only led China to a period of industrialization, urbanization, informatization and agricultural modernization, but also exacerbated the situation of the urban–rural dual structure. Based on the review of current studies, we first used the analytic hierarchy process（AHP） method to evaluate the urban–rural development and transformation level by population transformation index, land transformation index, industrial transformation index and social transformation index between 1996 and 2012 around the Bohai Rim Region. Then, based on the results of each index, we used the exploratory spatial data analysis（ESDA） method to investigate the spatial autocorrelation of the change in the urban–rural development transformation index during the 16-year period using Global Moran＇s I index and Local Moran＇s I index. Finally, we investigated the mechanism of change of the urban–rural development transformation index at county level, summarizing five main factors：（1） the radiation from the surrounding big cities,（2） the acceleration of the urbanization process,（3） the upgrading of the industrial structure,（4） the publishing and implementation of a macro development strategy and regional policy, and（5） natural factors such as topology.展开更多
The great success of US commercial shale gas exploitation stimulates the shale gas development in China,subsequently,the corresponding supporting policies were issued in the 12th Five-Year Plan.But from the experience...The great success of US commercial shale gas exploitation stimulates the shale gas development in China,subsequently,the corresponding supporting policies were issued in the 12th Five-Year Plan.But from the experience in the US shale gas development,we know that the resulted environmental threats are always an unavoidable issue,but no uniform and standard evaluation system has yet been set up in China.The comprehensive environment refers to the combination of natural ecological environment and external macro-environment.In view of this,we conducted a series of studies on how to set up a comprehensive environmental impact assessment system as well as the related evaluation methodology and models.First,we made an in-depth investigation into shale gas development procedures and any possible environmental impacts,and then compared,screened and modified environmental impact assessment methods for shale gas development.Also,we established an evaluating system and assessment models according to different status of the above two types of environment:the correlation matrix method was employed to assess the impacts on natural ecological environment and the optimization distance method was modified to evaluate the impacts on external macro-environment.Finally,we substitute the two subindexes into the comprehensive environmental impact assessment model and achieved the final numerical result of environmental impact assessment.This model can be used to evaluate if a shale gas project has any impact on environment,compare the impacts before and after a shale gas development project,or the impacts of different projects.展开更多
Today the cycle time of the product develop is requ ir ed to be shortened. At the same time the requirement of the customers becomes mo re and more diverse and complex. The capability of the develop unit is limited b ...Today the cycle time of the product develop is requ ir ed to be shortened. At the same time the requirement of the customers becomes mo re and more diverse and complex. The capability of the develop unit is limited b ecause of the existence of heterogeneous systems and distributed environments. I n this paper, we bring forward a new approach to solve the problem in product de velopment process. We also settle part key technologies in it. A great deal of information from all kinds of sources in the distributed develop ment process is interweaved. The solution to organize the workflow and manage th e information in the process is called for anxiously. We use a new approach that is asynchronous and synchronous coupling product development approach based on the network. The approach extends the develop process from the time axis. Then t he activities in the process are organized from the asynchronous and synchronous aspects. The state of every activity projects at the ASN (active semantic netwo rk). The ASN includes decision system, intelligent agent, user interface and net work. The ASN decides the types and states of the activities and deals with the couple relationship among them. The knowledge stored in ASN is open to all users through the relative interfaces. Every specialist keeps contact with their user s relying on collaborative platform implements CSCW (computer support collaborat ive work) that integrated product/process design and development. The lack of gl obal communication in product development process can be prevented in the most d egree. The key technologies that exist in the asynchronous and synchronous coupling pro duct develop approach include: integrated development structure, orderly organiz ation of information, transparent management of process, agile transfer of infor mation and rapid prototype. The development process can be completed quickly by these technologies. The technologies involve wide content. In this paper, we dis cuss some key technologies. We validate the approach by the projectrapid response manufacturing a pplication in the distributed environment. The expensive device, high technology and low using lead to RE (Rapid engineering) and RP (Rapid prototype) service a pplication by the network. RE and RP develop rapidly due to the accelerated prod uct development process. RE and RP application service platform is built in the project.展开更多
Product development process management plays an important role in concurrent engineering (CE). The integration platform is a useful tool for effectively supporting the software development and integration. Based on th...Product development process management plays an important role in concurrent engineering (CE). The integration platform is a useful tool for effectively supporting the software development and integration. Based on the analysis of practical requirements for product development process management for CE, a CORBA-based integration platform of product development process management (IP-PDPM) is designed and developed. The design principles for IP-PDPM are described. The system architecture and functions of the platform are given, the key technologies for the implementation of IP-PDPM are presented, the application integration mechanism and its implementation techniques are also detailed.展开更多
Grape pistil has an important influence on fruit size and quality.However,there were few studies on grape ovary,and the development process of the ovary is still unclear.Therefore,in this paper,four different grape va...Grape pistil has an important influence on fruit size and quality.However,there were few studies on grape ovary,and the development process of the ovary is still unclear.Therefore,in this paper,four different grape varieties with different lengths of small inflorescences,namely‘Musct Hambourg’grape(Vitis vinifera),‘Concord’grape(Vitis labrusca),‘ShanPuTao’grape(Vitis amurensis)and‘GongNiang2Hao’grape(Vitis amurensis×Vitis vinifera)were used as test materials.Four varieties ovary were significant differences by means of stereomicroscope,paraffin section.The expression of ovary determining gene VvAGAMOUS(VvAG)and its development related genes VvCRABS CLAW(VvCRC)and VvAGAMOUS-LIKE 11(VvAGL11)with similar functions during the development of different grape varieties were preliminarily explored using fluorescence quantitative test.The relationship between VvAG and VvCRC,VvAG and VvAGL11 were analyzed using Y1H assay.Our results showed that there were obvious abdominal sutures on the surface of expect for‘Musct Hambourg’grape,and existing poly carpels.The ovary development of‘ShanPuTao’and‘GongNiang2Hao’grape was completed when the inflorescence length was less than 1 cm,while the‘Concord’and‘Musct Hambourg’grape were fully developed when the length of inflorescence was 3–4 and 4–5 cm,respectively.VvAG and VvCRC began to express in large quantities after the formation of stamen primordia,while VvAGL11 during the forming of ovule primordia.Therefore,VvAG and VvCRC mainly regulated the development of stamens and carpels and also promote the development of ovules,while VvAGL11 major regulated the development of ovules.The promoters of VvCRC and VvAGL11 were bound by VvAG.This study provides an important theoretical basis for further research on the molecular mechanism of grape ovary development.展开更多
This paper studies the scheduling of design projects in concurrent development process with uncertain number of feedback revisions. An optimization based methodology that combines heuristic algorithm, artificial intel...This paper studies the scheduling of design projects in concurrent development process with uncertain number of feedback revisions. An optimization based methodology that combines heuristic algorithm, artificial intelligence (fuzzy, genetic algorithm) and scheduling theory is developed. In the algorithm, weighting values of some key factors are defined by genetic algorithm. In addition, fuzzy logic is used to decide the ability coefficients of different roles taken by designers. Moreover, the process of pre-release and feedback revision is realized. Simulation example is a fraction of practical development project, and satisfied results are obtained.展开更多
A methodology is presented to identify environmental impact minimization alternatives for reaction processes and assess their environmental performance. The potential environmental impact (PEI) scheme can be used to v...A methodology is presented to identify environmental impact minimization alternatives for reaction processes and assess their environmental performance. The potential environmental impact (PEI) scheme can be used to visibly display the transformation relationships among different types of PEI, identify the sources of environmental impacts, and propose alternatives for eliminating or minimizing the impacts. To evaluate the environmental performance of the alternatives effectively, some new indices, such as PEI input rate of non-products, PEI output rate of non-products per profit and the PEI conversion efficiency are proposed. Finally, the application of the methodology is illustrated using an industrial case study.展开更多
The purpose of this paper is to evaluate the impact of lean product development （LPD） in the Brazilian automotive sector. A mailed-questionnaire survey was used to examine 23 questions about LPD principles and pract...The purpose of this paper is to evaluate the impact of lean product development （LPD） in the Brazilian automotive sector. A mailed-questionnaire survey was used to examine 23 questions about LPD principles and practices. The target population for the study was Brazil＇s largest product development and design companies. The study identified that although the automobile sector is seen as a reference in the adoption of lean practices, there is still potential for improvement by establishing partnership relations with suppliers, and with those on the other points of the chain by identifying what provides value to clients. Set-based concurrent engineering is also a practice that needs to be better developed, as well as the value stream mapping tool to identify waste and activities that add value to the product development process. There has been no previous study of this nature in Brazil that characterizes the sector and highlights its importance in relation to the global scene, providing incentives to international investors. The value of the work is in the results that allow diagnosing the lean development practices that are most used in the automotive sector. Moreover, the survey questions can be applied in other economic sectors and at companies of other sizes. The study contributed to providing a systematic view of the product development process from the perspective of people, processes, and technology, and assists companies and academics manage change.展开更多
The Shanghai Cooperation Organization(SCO)has withstood storms to create a cooperative platform in Central Asia that conforms to the trend of the times,meets regional needs,and serves its member states’interests.SCO...The Shanghai Cooperation Organization(SCO)has withstood storms to create a cooperative platform in Central Asia that conforms to the trend of the times,meets regional needs,and serves its member states’interests.SCO’s commitment to innovative thinking,security cooperation and regional coordination has contributed to regional stability and development and to gaining experience for establishing regional and global order.China-Russia cooperation,efforts by the“Shanghai Five,”relations among member states,and external pressure have been the main driving forces supporting a huge increase in trade in the past 20 years.For regional development and stability and a greater role in global governance,the SCO should continue taking the long-term perspective in planning and policy.展开更多
基金This work was funded by the Deutsche Forschungsgemeinschaft(DFG——German Research Foundation),grant no.HA 2038/8-1——425916241.
文摘Scientific modeling provides mathematical abstractions of real-world systems and builds software as implementations of these mathematical abstractions.Ocean science is a multidisciplinary discipline developing scientific models and simulations as ocean sys-tem models that are an essential research asset.In software engineering and information systems research,modeling is also an essential activity.In particular,business process modeling for business process management and systems engineering is the activity of representing processes of an enterprise,so that the current process may be analyzed,improved and automated.In this paper,we employ process modeling for analyzing sci-entific software development in ocean science to advance the state in engineering of ocean system models and to better understand how ocean system models are developed and maintained in ocean science.We interviewed domain experts in semi-structured inter-views,analyzed the results via thematic analysis,and modeled the results via the Busi-ness Process Modeling Notation(BPMN).The processes modeled as a result describe an aspired state of software development in the domain,which are often not(yet)imple-mented.This enables existing processes in simulation-based system engineering to be improved with the help of these process models.
文摘Based on the analysis of the development process system status of domestic and foreign civil aircraft airborne system suppliers,this paper proposes the overall construction idea of"a set of civil aircraft process system"based on IPD(Integrated product development)in the organization.The development stage,process,activity and task are the logical framework elements of the system construction."Based on process decomposition,vertical stratification,horizontal segmentation,combination of special and common,process customized to tools,role and process integration,giving full consideration to the interface between supplier management and process modules"etc.are the concrete ideas.Moreover,formulate top⁃level system construction standards,implemented by process system management tool platform,so that the process system and development work can be effectively integrated to effectively guide the development work of airborne system suppliers,and meet the quality and airworthiness requirements of civil aircraft development.Through the development application of a certain type of flight control system,the process system and tool platform were verified and optimized in practice.
基金“Promoting research by writing”:Exploring the code of writing,supported by the Special Fund for basic scientific research of the Central University,Northwestern Polytechnical University(project no.KCJS23WT25).“Research on the construction of the linking-up curriculum system:Taking the industry characteristic research university as an example”was established by the Ministry of Education’s Youth Fund for Humanities and Social Sciences,the Department of Social Sciences of the Ministry of Education(project no.23YJC880099).
文摘The development of women’s higher education in China can be divided into four stages:emergence(1908-1948);foundation(1949-1976);accelerating development(1977-2008);and the qualitative leap(2009-2020).This work considers the principal institutional mechanisms that contributed to this development.First,flexibly planned parenthood gradually promoted gender equality and openness in society facilitated by systematic“awards,grants,and loans”initiatives to support women’s higher education economically.Second,compulsory education ensured that left-out and migrant children had access to higher education.Third,effective connectivity across different education types bridged education gaps between those with different levels of education.Fourth,China made great efforts to invite and integrate international experiences that promoted the development of women’s higher education.Looking beyond these achievements,we also discuss the future trends of women’s higher education in China.
文摘Dispersed and peripheral spaces in the urban core are influenced both by the trend towards constant growth as well as social ways of life which are constantly evolving. Following a connotation, these two factors therefore play a crucial role in defining the alternation of urban space--in particular, that of the centers. The main focus of this research article is on the methodology used in the survey and evaluation of ＂centralities＂ as well as their developments over the past four decades （1974-2014） in approaches to urban development that has been developed in Graz.~ The analysis has drawn on the four editions （＂evolution＂） of approaches to urban development as conceived by the city of Graz in order to examine their verbal characteristics in regard to centralities. At the same time, the analysis does not examine presentations of plans which exist in supplementary forms （e.g., explanatory reports and supplemented plans）--it restricts itself solely to the various plans set out in the STEKs.2 The highest degree of accuracy has been applied to the notion of ＂centralis＂ in approaches to urban development. The goal of the research project was to depict the modulation of the notion of ＂centrality＂ in the urban context as a space-forming dimension. Furthermore, it clearly shows the extent to which the notion of the ＂centre＂ （in the widest sense of the word） has become distanced from qualitative, spatial development and at the current time of urban development is experiencing a sort of Renaissance. In the field of ＂urban development＂, architectural references in the context of＂centrality＂ have scarcely been researched. This has led to the opening-up of a complex interdisciplinary research field. In order to make the complex architectural determinants of ＂centrality＂ more accessible to the participating disciplines, approaches to urban development have been explored in the form of a social and spatial analysis.
基金supported by Natural Science Foundation of China(No.31930067)Natural Science Foundation of Sichuan Province(No.23NSFSC5880)+2 种基金Chengdu Medical Research Project(No.2022004)Natural Science Foundation of Clinical Medical College and Affiliated Hospital of Chengdu University(No.Y202206)Postdoctoral Research and Development Fund of West China Hospital,Sichuan University(No.2023HXBH052).
文摘Vascular stents play an important role in the minimally invasive treatment of vascular diseases,such as vascular stenosis,vascular aneurysm,vascular dissection and vascular atherosclerotic plaque disease.Bare metal stents were initially fabricated;however,the incidence of complications such as thrombosis,inflammation,restenosis,vascular injury,displacement and endoleakage is still high after implantation.To overcome these complications,several strategies for designing functional vascular stents have been carried out.Drug-eluting stents,biodegradable stents and bionic stents were manufactured and investigated.This review aims to comprehensively analyze the vascular diseases suitable for stent implantation treatment,tissue reactions after implantation,the materials and manufacturing techniques used to fabricate vascular stents,the various application scenarios in which they could be used to treat vascular lesions and the development process of vascular stents.Future development trends of vascular stents are expected to prioritize their performance,biocompatibility,and clinical accessibility.The design of vascular stents may be transformed or improved to better fulfill the rehabilitation requirements of vascular disease patients.Finally,various application scenarios may be used to treat vascular or even nonvascular diseases via endovascular access.
文摘Fischer-Tropsch synthesis(FTS)and hydroformylation are pivotal chemical processes for converting syngas and olefins into valuable hydrocarbons and chemicals.Recent advancements in catalyst design,reaction mechanisms,and process optimization have significantly improved the efficiency,selectivity,and sustainability of these processes.This Account introduces the relevant research activities in the Research Center for Catalysis in Syngas Conversion and Fine Chemicals(DNL0805)of Dalian Institute of Chemical Physics(DICP),Chinese Academy of Sciences.The reactions of interests include FTS,heterogeneous hydroformylation of olefins,alcohol dehydration and oxidation,andα-olefin polymerization,with the emphasis on developing innovative catalysts and processes to address the challenges of traditional processes.Exemplified by the discovery of robust Co-Co_(2)C/AC for FTS and Rh_(1)/POPs-PPh_(3) for heterogeneous hydroformylation of olefins,it demonstrates how lab-scale fundamental understandings on the active sites of catalysts leads to pilot-plant scale-up and finally commercial technologies.Perspectives on the challenges and directions for future developments in these exciting fields are provided.
文摘The development of chemical technologies,which involves a multistage process covering laboratory research,scale‐up to industrial deployment,and necessitates interdisciplinary collaboration,is often accompanied by substantial time and economic costs.To address these challenges,in this work,we report ChemELLM,a domain‐specific large language model(LLM)with 70 billion parameters for chemical engineering.ChemELLM demonstrates state‐of‐the‐art performance across critical tasks ranging from foundational understanding to professional problem‐solving.It outperforms mainstream LLMs(e.g.,O1‐Preview,GPT‐4o,and DeepSeek‐R1)on ChemEBench,the first multidimensional benchmark for chemical engineering,which encompasses 15 dimensions across 101 distinct essential tasks.To support robust model development,we curated ChemEData,a purpose‐built dataset containing 19 billion tokens for pre‐training and 1 billion tokens for fine‐tuning.This work establishes a new paradigm for artificial intelligence‐driven innovation,bridging the gap between laboratory‐scale innovation and industrial‐scale implementation,thus accelerating technological advancement in chemical engineering.ChemELLM is publicly available at https://chemindustry.iflytek.com/chat.
基金supported partly by the Fundamental Research Funds for Central Universities(No.06500203 and No.00007735).
文摘China is currently vigorously implementing the“energy conservation and emission reduction”and“dual carbon”strategies.As the most resource-advantaged light metal material in China,Magnesium(Mg)alloy is progressively expanding its application in automobile,rail transportation,aerospace,medical,and electronic products.Chongqing University,Shanghai Jiaotong University,and Australian National University have conducted extensive research on the preparation,properties,and processes of Mg alloys.In the past 20 years,the proportion of Mg alloy in the automotive industry has gradually expanded,whereas currently the design and development of Mg alloy parts for automobiles has rarely been reported.Thus,the application models and typical parts cases of Mg alloy are summarized mainly from the four systems of the whole vehicle(body system,chassis system,powertrain system,interior,and exterior system).Subsequently,two actual original equipment manufacturers(OEM)cases are used to introduce the development logic of reliable die-cast Mg alloy,including forward design,formability analysis,process design analysis,structural redesign,manufacturing,and testing,aiming to share the methods,processes,and focus of attention of automotive OEMs for developing Mg alloy parts to enhance the confidence and motivation of applying Mg alloy in automotive field.Eventually,the multiple challenges faced by Mg alloy materials are sorted out and how to face these challenges are discussed.National policies and regulations,environmental protection and energy saving,and consumer demand will continue to promote the application of Mg.
基金the National Natural Science foundation of China! (59995440)
文摘This paper reviewed the trend and development of semi-solid metal technique. The processes and mechanisms for producing slurry of SSM and its industrial applications have been summarized and discussed. Discussions on the basic rheological theory are presented for more applications. Further consideration of the development and application of SSM technique is also proposed.
基金the Basic Research Program of the Korea Science & Engineering Foundation (KoSEF, No. R01-2006-000-10786-0).
文摘This article presents a multiscale simulation approach starting at the molecular level for the adsorption process development. A grand canonical Monte Carlo method is used for the prediction of adsorption isotherms of methanol on an activated carbon at the molecular level. The adsorption isotherms obtained in the linear region （or adsorption constant） are exploited as a model parameter required for the adsorption process simulation. The adsorption process model described by a set of partial differential equations （PDEs） is solved by using the conservation element and solution element method, which produces a fast and an accurate numerical solution to PDEs. The simulation results obtained from the adsorption constant estimated at the molecular level are in good agreement with the experimental results of the pulse response. The systematical multiscale simulation approach addressed in this study may be useful to accelerate the adsorption process development by reducing the number of experiments.
文摘China is a country abundant in lakes. Lake science development in China, not only aims at the international frontiers of correlative subject development, but also focuses on the national strategic needs in different ages. This paper describes the general situation and distribution characteristics of Chinese lakes, systematically reviews development process of Chinese lake science and its progress in lake physics, lake chemistry, lake biology, lake sediment and lake-watershed management, finally looks forward to the developing tendency of Chinese lake science in future.
基金National Natural Science Foundation of China,No.41130748No.41471143
文摘China＇s reform and opening-up policy has brought the country a great development opportunity. The high-speed growth of the economy not only led China to a period of industrialization, urbanization, informatization and agricultural modernization, but also exacerbated the situation of the urban–rural dual structure. Based on the review of current studies, we first used the analytic hierarchy process（AHP） method to evaluate the urban–rural development and transformation level by population transformation index, land transformation index, industrial transformation index and social transformation index between 1996 and 2012 around the Bohai Rim Region. Then, based on the results of each index, we used the exploratory spatial data analysis（ESDA） method to investigate the spatial autocorrelation of the change in the urban–rural development transformation index during the 16-year period using Global Moran＇s I index and Local Moran＇s I index. Finally, we investigated the mechanism of change of the urban–rural development transformation index at county level, summarizing five main factors：（1） the radiation from the surrounding big cities,（2） the acceleration of the urbanization process,（3） the upgrading of the industrial structure,（4） the publishing and implementation of a macro development strategy and regional policy, and（5） natural factors such as topology.
文摘The great success of US commercial shale gas exploitation stimulates the shale gas development in China,subsequently,the corresponding supporting policies were issued in the 12th Five-Year Plan.But from the experience in the US shale gas development,we know that the resulted environmental threats are always an unavoidable issue,but no uniform and standard evaluation system has yet been set up in China.The comprehensive environment refers to the combination of natural ecological environment and external macro-environment.In view of this,we conducted a series of studies on how to set up a comprehensive environmental impact assessment system as well as the related evaluation methodology and models.First,we made an in-depth investigation into shale gas development procedures and any possible environmental impacts,and then compared,screened and modified environmental impact assessment methods for shale gas development.Also,we established an evaluating system and assessment models according to different status of the above two types of environment:the correlation matrix method was employed to assess the impacts on natural ecological environment and the optimization distance method was modified to evaluate the impacts on external macro-environment.Finally,we substitute the two subindexes into the comprehensive environmental impact assessment model and achieved the final numerical result of environmental impact assessment.This model can be used to evaluate if a shale gas project has any impact on environment,compare the impacts before and after a shale gas development project,or the impacts of different projects.
文摘Today the cycle time of the product develop is requ ir ed to be shortened. At the same time the requirement of the customers becomes mo re and more diverse and complex. The capability of the develop unit is limited b ecause of the existence of heterogeneous systems and distributed environments. I n this paper, we bring forward a new approach to solve the problem in product de velopment process. We also settle part key technologies in it. A great deal of information from all kinds of sources in the distributed develop ment process is interweaved. The solution to organize the workflow and manage th e information in the process is called for anxiously. We use a new approach that is asynchronous and synchronous coupling product development approach based on the network. The approach extends the develop process from the time axis. Then t he activities in the process are organized from the asynchronous and synchronous aspects. The state of every activity projects at the ASN (active semantic netwo rk). The ASN includes decision system, intelligent agent, user interface and net work. The ASN decides the types and states of the activities and deals with the couple relationship among them. The knowledge stored in ASN is open to all users through the relative interfaces. Every specialist keeps contact with their user s relying on collaborative platform implements CSCW (computer support collaborat ive work) that integrated product/process design and development. The lack of gl obal communication in product development process can be prevented in the most d egree. The key technologies that exist in the asynchronous and synchronous coupling pro duct develop approach include: integrated development structure, orderly organiz ation of information, transparent management of process, agile transfer of infor mation and rapid prototype. The development process can be completed quickly by these technologies. The technologies involve wide content. In this paper, we dis cuss some key technologies. We validate the approach by the projectrapid response manufacturing a pplication in the distributed environment. The expensive device, high technology and low using lead to RE (Rapid engineering) and RP (Rapid prototype) service a pplication by the network. RE and RP develop rapidly due to the accelerated prod uct development process. RE and RP application service platform is built in the project.
文摘Product development process management plays an important role in concurrent engineering (CE). The integration platform is a useful tool for effectively supporting the software development and integration. Based on the analysis of practical requirements for product development process management for CE, a CORBA-based integration platform of product development process management (IP-PDPM) is designed and developed. The design principles for IP-PDPM are described. The system architecture and functions of the platform are given, the key technologies for the implementation of IP-PDPM are presented, the application integration mechanism and its implementation techniques are also detailed.
基金financially supported from the Shanxi Youth Science Research Project(Grant No.20210302124067)the Shanxi Agricultural University Doctoral Research Startup Project(Grant No.2021BQ32)+2 种基金the Shanxi Provincial Doctoral Graduates and Postdoctoral ResearchersWorking in Shanxi Reward Fund Research Project(Grant No.SXBYKY2021075)the National Youth Science Foundation Project(Grant No.32202456)the earmarked fund for Modern Agro-Industry Technology Research System.
文摘Grape pistil has an important influence on fruit size and quality.However,there were few studies on grape ovary,and the development process of the ovary is still unclear.Therefore,in this paper,four different grape varieties with different lengths of small inflorescences,namely‘Musct Hambourg’grape(Vitis vinifera),‘Concord’grape(Vitis labrusca),‘ShanPuTao’grape(Vitis amurensis)and‘GongNiang2Hao’grape(Vitis amurensis×Vitis vinifera)were used as test materials.Four varieties ovary were significant differences by means of stereomicroscope,paraffin section.The expression of ovary determining gene VvAGAMOUS(VvAG)and its development related genes VvCRABS CLAW(VvCRC)and VvAGAMOUS-LIKE 11(VvAGL11)with similar functions during the development of different grape varieties were preliminarily explored using fluorescence quantitative test.The relationship between VvAG and VvCRC,VvAG and VvAGL11 were analyzed using Y1H assay.Our results showed that there were obvious abdominal sutures on the surface of expect for‘Musct Hambourg’grape,and existing poly carpels.The ovary development of‘ShanPuTao’and‘GongNiang2Hao’grape was completed when the inflorescence length was less than 1 cm,while the‘Concord’and‘Musct Hambourg’grape were fully developed when the length of inflorescence was 3–4 and 4–5 cm,respectively.VvAG and VvCRC began to express in large quantities after the formation of stamen primordia,while VvAGL11 during the forming of ovule primordia.Therefore,VvAG and VvCRC mainly regulated the development of stamens and carpels and also promote the development of ovules,while VvAGL11 major regulated the development of ovules.The promoters of VvCRC and VvAGL11 were bound by VvAG.This study provides an important theoretical basis for further research on the molecular mechanism of grape ovary development.
文摘This paper studies the scheduling of design projects in concurrent development process with uncertain number of feedback revisions. An optimization based methodology that combines heuristic algorithm, artificial intelligence (fuzzy, genetic algorithm) and scheduling theory is developed. In the algorithm, weighting values of some key factors are defined by genetic algorithm. In addition, fuzzy logic is used to decide the ability coefficients of different roles taken by designers. Moreover, the process of pre-release and feedback revision is realized. Simulation example is a fraction of practical development project, and satisfied results are obtained.
基金National Natural Science Foundation of China(No.20176045)Major State Basic Research Development Program(No.G20000263)
文摘A methodology is presented to identify environmental impact minimization alternatives for reaction processes and assess their environmental performance. The potential environmental impact (PEI) scheme can be used to visibly display the transformation relationships among different types of PEI, identify the sources of environmental impacts, and propose alternatives for eliminating or minimizing the impacts. To evaluate the environmental performance of the alternatives effectively, some new indices, such as PEI input rate of non-products, PEI output rate of non-products per profit and the PEI conversion efficiency are proposed. Finally, the application of the methodology is illustrated using an industrial case study.
文摘The purpose of this paper is to evaluate the impact of lean product development （LPD） in the Brazilian automotive sector. A mailed-questionnaire survey was used to examine 23 questions about LPD principles and practices. The target population for the study was Brazil＇s largest product development and design companies. The study identified that although the automobile sector is seen as a reference in the adoption of lean practices, there is still potential for improvement by establishing partnership relations with suppliers, and with those on the other points of the chain by identifying what provides value to clients. Set-based concurrent engineering is also a practice that needs to be better developed, as well as the value stream mapping tool to identify waste and activities that add value to the product development process. There has been no previous study of this nature in Brazil that characterizes the sector and highlights its importance in relation to the global scene, providing incentives to international investors. The value of the work is in the results that allow diagnosing the lean development practices that are most used in the automotive sector. Moreover, the survey questions can be applied in other economic sectors and at companies of other sizes. The study contributed to providing a systematic view of the product development process from the perspective of people, processes, and technology, and assists companies and academics manage change.
文摘The Shanghai Cooperation Organization(SCO)has withstood storms to create a cooperative platform in Central Asia that conforms to the trend of the times,meets regional needs,and serves its member states’interests.SCO’s commitment to innovative thinking,security cooperation and regional coordination has contributed to regional stability and development and to gaining experience for establishing regional and global order.China-Russia cooperation,efforts by the“Shanghai Five,”relations among member states,and external pressure have been the main driving forces supporting a huge increase in trade in the past 20 years.For regional development and stability and a greater role in global governance,the SCO should continue taking the long-term perspective in planning and policy.
