1982 Minheella,Song Qishan et al,Symposium on Petroleum Geology,4,92—93. Type species:Minheella minheensis Song et Cheng(pl.21,figs.9-12) Diagnosis:Carapace large,lateral view subelliptical,subrectangular orovate.Lef...1982 Minheella,Song Qishan et al,Symposium on Petroleum Geology,4,92—93. Type species:Minheella minheensis Song et Cheng(pl.21,figs.9-12) Diagnosis:Carapace large,lateral view subelliptical,subrectangular orovate.Left valve larger than right,overlapping the latter along dorsal andventral margins.Posterior ends of two valves asymmetrical,that of leftvalve swollen or node like,pointed post-laterally.The swollen part separa-ted from the carapace margin by a shallow furrow.In some species posteriorend of right valve overlaps that of left valve.Inner lamella moderately wide.展开更多
The current journal is mainly focused in zoological systematics. According to Systematics Agenda 2000(1994), systematics is the science built on the following tasks: Taxonomy—the science of discovering, describing, a...The current journal is mainly focused in zoological systematics. According to Systematics Agenda 2000(1994), systematics is the science built on the following tasks: Taxonomy—the science of discovering, describing, and classifying species or groups of species(together termed taxa);Phylogenetic analysis—the discovery of the evolutionary relationships among a group of species;and Classification—the grouping of species, ultimately on the basis of evolutionary relationships.展开更多
Optical solitons,as self-sustaining waveforms in a nonlinear medium where dispersion and nonlinear effects are balanced,have key applications in ultrafast laser systems and optical communications.Physics-informed neur...Optical solitons,as self-sustaining waveforms in a nonlinear medium where dispersion and nonlinear effects are balanced,have key applications in ultrafast laser systems and optical communications.Physics-informed neural networks(PINN)provide a new way to solve the nonlinear Schrodinger equation describing the soliton evolution by fusing data-driven and physical constraints.However,the grid point sampling strategy of traditional PINN suffers from high computational complexity and unstable gradient flow,which makes it difficult to capture the physical details efficiently.In this paper,we propose a residual-based adaptive multi-distribution(RAMD)sampling method to optimize the PINN training process by dynamically constructing a multi-modal loss distribution.With a 50%reduction in the number of grid points,RAMD significantly reduces the relative error of PINN and,in particular,optimizes the solution error of the(2+1)Ginzburg–Landau equation from 4.55%to 1.98%.RAMD breaks through the lack of physical constraints in the purely data-driven model by the innovative combination of multi-modal distribution modeling and autonomous sampling control for the design of all-optical communication devices.RAMD provides a high-precision numerical simulation tool for the design of all-optical communication devices,optimization of nonlinear laser devices,and other studies.展开更多
INTRODUCTION.Crustal velocity model is crucial for describing the subsurface composition and structure,and has significant implications in offshore oil and gas exploration and marine geophysical engineering(Xie et al....INTRODUCTION.Crustal velocity model is crucial for describing the subsurface composition and structure,and has significant implications in offshore oil and gas exploration and marine geophysical engineering(Xie et al.,2024).Currently,travel time tomography is the most commonly used method for velocity modeling based on ocean bottom seismometer(OBS)data(Zhang et al.,2023;Sambolian et al.,2021).This method usually assumes that the sub-seafloor structure is layered,and therefore faces challenges in high-precision modeling with strong lateral discontinuities.展开更多
A bound state formalism derived from a fermion-boson symmetric Lagrangian has been used to calculate the nucleon masses, the charge neutrality of the neutron, the magnetic moments and the electromagnetic form factor r...A bound state formalism derived from a fermion-boson symmetric Lagrangian has been used to calculate the nucleon masses, the charge neutrality of the neutron, the magnetic moments and the electromagnetic form factor ratios μpGEp/GMpand μnGEn/GMn. A quantitative description is obtained, assuming a mixing of a scalar bound state of 3(f f¯)fstructure with its corresponding vector (f f¯)fstate (f indicating massless elementary fermions). Only a few parameters are needed, mainly fixed by energy and momentum conservation. The nucleon stability is explained by an extra binding in the confinement potential, negative for electric and positive for magnetic binding of the proton, and opposite for the neutron. The stronger electric extra binding of the proton allows a decay of the neutron to proton and electron.展开更多
Both, the dilemma to find a quantum field theory consistent with Einstein’s law of relativity and the problem to describe existing particles as bound states of matter has been solved by calculating bound state matrix...Both, the dilemma to find a quantum field theory consistent with Einstein’s law of relativity and the problem to describe existing particles as bound states of matter has been solved by calculating bound state matrix elements from a dual fermion-boson Lagrangian. In this formalism, the fermion binding energies are compensated by boson energies, indicating that particles can be generated out of the vacuum. This yields quantitative solutions for various mesons ω (0.78 GeV) - Υ (9.46 GeV) and all leptons e, μ and τ, with uncertainties in the extracted properties of less than 1‰. For transparency, a Web-page with the address htpps://h2909473.stratoserver.net has been constructed, where all calculations can be run on line and also the underlying fortran source code can be inspected.展开更多
The massive vector bosons Z o, W ± and the scalar Higgs-boson H o assumed in weak interaction theory, but also the six quarks required in strong interactions are well understood in an alternative quantum field th...The massive vector bosons Z o, W ± and the scalar Higgs-boson H o assumed in weak interaction theory, but also the six quarks required in strong interactions are well understood in an alternative quantum field theory of fermions and bosons: Z o and W ± as well as all quark-antiquark states (here only the tt¯state is discussed) are described by bound states with scalar coupling between their massless constituents and have a structure similar to leptons. However, the scalar Higgs-boson H o corresponds to a state with vector coupling between the elementary constituents. Similar scalar states are expected also in the mass region of the mesons ω (0.782 GeV) - Υ ( 9.46 GeV). The underlying calculations can be run on line using the Web-address https://h2909473.stratoserver.net.展开更多
The current journal is mainly focused in zoological systematics.According to Systematics Agenda 2000(1994),systematics is the science built on the following tasks:Taxonomy-the science of discovering,describing,and cla...The current journal is mainly focused in zoological systematics.According to Systematics Agenda 2000(1994),systematics is the science built on the following tasks:Taxonomy-the science of discovering,describing,and classifying species or groups of species(together termed taxa);Phylogenetic analysisthe discovery of the evolutionary relationships among a group of species;and Classification-the grouping of species,ultimately on the basis of evolutionary relationships.展开更多
The current journal is mainly focused in zoological systematics.According to Systematics Agenda 2000(1994),systematics is the science built on the following tasks:Taxonomy-the science of discovering,describing,and cla...The current journal is mainly focused in zoological systematics.According to Systematics Agenda 2000(1994),systematics is the science built on the following tasks:Taxonomy-the science of discovering,describing,and classifying species or groups of species(together termed taxa);Phylogenetic analysisthe discovery of the evolutionary relationships among a group of species;and Classificationthe grouping of species,ultimately on the basis of evolutionary relationships.展开更多
The current journal is mainly focused in zoological systematics.According to Systematics Agenda 2000(1994),systematics is the science built on the following tasks:Taxonomy-the science of discovering,describing,and cla...The current journal is mainly focused in zoological systematics.According to Systematics Agenda 2000(1994),systematics is the science built on the following tasks:Taxonomy-the science of discovering,describing,and classifying species or groups of species(together termed taxa);Phylogenetic analysis-the discovery of the evolutionary relationships among a group of species;and Classification-the grouping of species,ultimately on the basis of evolutionary relationships.展开更多
Our knowledge of renal cell carcinoma(RCC) is rapidly expanding. For those who diagnose and treat RCC, it is important to understand the new developments. In recent years, many new renal tumors have been described and...Our knowledge of renal cell carcinoma(RCC) is rapidly expanding. For those who diagnose and treat RCC, it is important to understand the new developments. In recent years, many new renal tumors have been described and defined, and our understanding of the biology and clinical correlates of these tumors is changing. Evolving concepts in Xp11 translocation carcinoma, mucinous tubular and spindle cell carcinoma, multilocular cystic clear cell RCC, and carcinoma associated with neuroblastoma are addressed within this review. Tubulocystic carcinoma, thyroid-like follicular carcinoma of kidney, acquired cystic disease-associated RCC, and clear cell papillary RCC are also described. Finally, candidate entities, including RCC with t(6;11) translocation, hybrid oncocytoma/chromophobe RCC, hereditary leiomyomatosis and RCC syndrome, and renal angiomyoadenomatous tumor are reviewed. Knowledge of these new entities is important for diagnosis, treatment and subsequent prognosis. This review provides a targeted summary of new developments in RCC.展开更多
Twenty-three temperate China species of Lachnum, Lachnum abnorme, L. angustum, L. brevipilosum, L. calosporum, L. calyculiforme, L. carneolum, L. ciliare, L. controversum, L. flavidulum, L. cf. fushanese, L. indicum, ...Twenty-three temperate China species of Lachnum, Lachnum abnorme, L. angustum, L. brevipilosum, L. calosporum, L. calyculiforme, L. carneolum, L. ciliare, L. controversum, L. flavidulum, L. cf. fushanese, L. indicum, L. kumaonicum, L. lushanese, L. minutum, L. montanum, L. cf. pteridophyllum, L. pygmaeum, L. sclerotii var. sclerotii, L. sclerotii var. sichuanense, L. subpygmeaum, L. tenuissimum, L. virgineum and L. willisii are reported, whose main characteristics are given in a formula of the described species, some of which are discussed below.展开更多
The paper searched for raw data about wild-caught fish, where a sigmoidal growth function described the mass growth significantly better than non-sigmoidal functions. Specifically, von Bertalanffy’s sigmoidal growth ...The paper searched for raw data about wild-caught fish, where a sigmoidal growth function described the mass growth significantly better than non-sigmoidal functions. Specifically, von Bertalanffy’s sigmoidal growth function (metabolic exponent-pair a = 2/3, b = 1) was compared with unbounded linear growth and with bounded exponential growth using the Akaike information criterion. Thereby the maximum likelihood fits were compared, assuming a lognormal distribution of mass (i.e. a higher variance for heavier animals). Starting from 70+ size-at-age data, the paper focused on 15 data coming from large datasets. Of them, six data with 400 - 20,000 data-points were suitable for sigmoidal growth modeling. For these, a custom-made optimization tool identified the best fitting growth function from the general von Bertalanffy-Pütter class of models. This class generalizes the well-known models of Verhulst (logistic growth), Gompertz and von Bertalanffy. Whereas the best-fitting models varied widely, their exponent-pairs displayed a remarkable pattern, as their difference was close to 1/3 (example: von Bertalanffy exponent-pair). This defined a new class of models, for which the paper provided a biological motivation that relates growth to food consumption.展开更多
Background liac arterial fibromuscular dysplasia(FMD)were rarely reported and their demographic,clinical and imaging features have not been precisely described resulting in uncertain therapeutic methods.Methods A lite...Background liac arterial fibromuscular dysplasia(FMD)were rarely reported and their demographic,clinical and imaging features have not been precisely described resulting in uncertain therapeutic methods.Methods A literature review was performed using Pubmed,Web of Science and Embase database.Original articles in English published since 1990 with full-text and detailed demographic,clinical,imaging and therapeutic information regarding iliac arterial FMD were included.展开更多
Density functional theory（DFT）-B3LYP level with the 6-311G＊＊（d,p） basis set was used to calculate a set of molecular quantum chemical descriptors of 12 chloroanilines. Quantitative structure-activity relationshi...Density functional theory（DFT）-B3LYP level with the 6-311G＊＊（d,p） basis set was used to calculate a set of molecular quantum chemical descriptors of 12 chloroanilines. Quantitative structure-activity relationship（QSAR） models of the bioconcentration factors（BCF） of the anilines in fish were established using some of the following calculated descriptors： EHOMO, ENHOMO, ELUMO, ENLUMO, ΔE1（= ELUMO- EHOMO）, ΔE2（= ENLUMO- ENHOMO）, dipole moment（μ）, molecular volume（V）, vibrational energy of 0 K（Ev）, thermodynamic energy（E）, heat capacity（Cv）, entropy（Sm） and the charge of benzene ring（Qph）. Using the variable selection and leaps-and-bounds regression, the quantum chemical descriptors derived directly from the molecular structures were employed to develop a linear QSAR model between the bioconcentration factors（BCF） and two descriptors（Sm, ENHOMO） of 12 chloroanilines. Statistically, the most significant one is a two-parameter linear equation with the correlation coefficient（R^2） of 0.981 and cross-validated correlation coefficient（Rcv^2） of 0.967. The established QSAR model has good stability and predictability based on the results from Rcv2 of leave-one-out cross-validation, AIC, FIT and tα/2. The quantum chemical analyses were performed from two aspects of frontier molecular orbital and entropy. The results show that two structural describers are crucial to the bioconcentration activity of chloroanilines.展开更多
The flutter characteristics of an actuator-fin system are investigated with structural nonlinearity and dynamic stiffness of the electric motor. The component mode substitution method is used to establish the nonlinea...The flutter characteristics of an actuator-fin system are investigated with structural nonlinearity and dynamic stiffness of the electric motor. The component mode substitution method is used to establish the nonlinear governing equations in time domain and frequency domain based on the fundamental dynamic equations of the electric motor and decelerator. The existing describing function method and a proposed iterative method are used to obtain the flutter characteristics containing preload freeplay nonlinearity when the control command is zero. A comparison between the results of frequency domain and those of time domain is studied. Simulations are carried out when the control command is not zero and further analysis is conducted when the freeplay angle is changed. The results show that structural nonlinearity and dynamic stiffness have a significant influence on the flutter characteristics. Limit cycle oscillations （LCOs） are observed within linear flutter boundary. The response of the actuator-fin system is related to the initial disturbance. In the nonlinear condition, the amplitude of the control command has an influence on the flutter characteristics.展开更多
The COVID-19 pandemic has posed a serious threat to global mental health.Multiple lines of evidence suggest that there is a varying yet considerable increase in mental health issues among the general population and vu...The COVID-19 pandemic has posed a serious threat to global mental health.Multiple lines of evidence suggest that there is a varying yet considerable increase in mental health issues among the general population and vulnerable groups.12 The aftermath is obscure and speculative from a social,economic,individual and public mental health perspective.Recently published studies support the existence of an emotional epidemic curve,describing a high probability of an increase in the burden of mental health issues in the post-pandemic era.34 Furthermore,previous major public health emergencies showed that more than half of the population devel-oped mental health problems and required mental health intervention.45 There is,therefore,an urgent need to reorganise existing mental health services to address the current unmet needs for mental health and to prepare for future challenges in the postpandemic era in terms of prevention and management.展开更多
文摘1982 Minheella,Song Qishan et al,Symposium on Petroleum Geology,4,92—93. Type species:Minheella minheensis Song et Cheng(pl.21,figs.9-12) Diagnosis:Carapace large,lateral view subelliptical,subrectangular orovate.Left valve larger than right,overlapping the latter along dorsal andventral margins.Posterior ends of two valves asymmetrical,that of leftvalve swollen or node like,pointed post-laterally.The swollen part separa-ted from the carapace margin by a shallow furrow.In some species posteriorend of right valve overlaps that of left valve.Inner lamella moderately wide.
文摘The current journal is mainly focused in zoological systematics. According to Systematics Agenda 2000(1994), systematics is the science built on the following tasks: Taxonomy—the science of discovering, describing, and classifying species or groups of species(together termed taxa);Phylogenetic analysis—the discovery of the evolutionary relationships among a group of species;and Classification—the grouping of species, ultimately on the basis of evolutionary relationships.
基金supported by the National Key R&D Program of China(Grant No.2022YFA1604200)National Natural Science Foundation of China(Grant No.12261131495)+1 种基金Beijing Municipal Science and Technology Commission,Adminitrative Commission of Zhongguancun Science Park(Grant No.Z231100006623006)Institute of Systems Science,Beijing Wuzi University(Grant No.BWUISS21)。
文摘Optical solitons,as self-sustaining waveforms in a nonlinear medium where dispersion and nonlinear effects are balanced,have key applications in ultrafast laser systems and optical communications.Physics-informed neural networks(PINN)provide a new way to solve the nonlinear Schrodinger equation describing the soliton evolution by fusing data-driven and physical constraints.However,the grid point sampling strategy of traditional PINN suffers from high computational complexity and unstable gradient flow,which makes it difficult to capture the physical details efficiently.In this paper,we propose a residual-based adaptive multi-distribution(RAMD)sampling method to optimize the PINN training process by dynamically constructing a multi-modal loss distribution.With a 50%reduction in the number of grid points,RAMD significantly reduces the relative error of PINN and,in particular,optimizes the solution error of the(2+1)Ginzburg–Landau equation from 4.55%to 1.98%.RAMD breaks through the lack of physical constraints in the purely data-driven model by the innovative combination of multi-modal distribution modeling and autonomous sampling control for the design of all-optical communication devices.RAMD provides a high-precision numerical simulation tool for the design of all-optical communication devices,optimization of nonlinear laser devices,and other studies.
基金financially supported by the National Key R&D Program of China(No.2023YFF0803404)the Zhejiang Provincial Natural Science Foundation(No.LY23D040001)+4 种基金the Open Research Fund of Key Laboratory of Engineering Geophysical Prospecting and Detection of Chinese Geophysical Society(No.CJ2021GB01)the Open Re-search Fund of Changjiang River Scientific Research Institute(No.CKWV20221011/KY)the ZhouShan Science and Technology Project(No.2023C81010)the National Natural Science Foundation of China(No.41904100)supported by Chinese Natural Science Foundation Open Research Cruise(Cruise No.NORC2019–08)。
文摘INTRODUCTION.Crustal velocity model is crucial for describing the subsurface composition and structure,and has significant implications in offshore oil and gas exploration and marine geophysical engineering(Xie et al.,2024).Currently,travel time tomography is the most commonly used method for velocity modeling based on ocean bottom seismometer(OBS)data(Zhang et al.,2023;Sambolian et al.,2021).This method usually assumes that the sub-seafloor structure is layered,and therefore faces challenges in high-precision modeling with strong lateral discontinuities.
文摘A bound state formalism derived from a fermion-boson symmetric Lagrangian has been used to calculate the nucleon masses, the charge neutrality of the neutron, the magnetic moments and the electromagnetic form factor ratios μpGEp/GMpand μnGEn/GMn. A quantitative description is obtained, assuming a mixing of a scalar bound state of 3(f f¯)fstructure with its corresponding vector (f f¯)fstate (f indicating massless elementary fermions). Only a few parameters are needed, mainly fixed by energy and momentum conservation. The nucleon stability is explained by an extra binding in the confinement potential, negative for electric and positive for magnetic binding of the proton, and opposite for the neutron. The stronger electric extra binding of the proton allows a decay of the neutron to proton and electron.
文摘Both, the dilemma to find a quantum field theory consistent with Einstein’s law of relativity and the problem to describe existing particles as bound states of matter has been solved by calculating bound state matrix elements from a dual fermion-boson Lagrangian. In this formalism, the fermion binding energies are compensated by boson energies, indicating that particles can be generated out of the vacuum. This yields quantitative solutions for various mesons ω (0.78 GeV) - Υ (9.46 GeV) and all leptons e, μ and τ, with uncertainties in the extracted properties of less than 1‰. For transparency, a Web-page with the address htpps://h2909473.stratoserver.net has been constructed, where all calculations can be run on line and also the underlying fortran source code can be inspected.
文摘The massive vector bosons Z o, W ± and the scalar Higgs-boson H o assumed in weak interaction theory, but also the six quarks required in strong interactions are well understood in an alternative quantum field theory of fermions and bosons: Z o and W ± as well as all quark-antiquark states (here only the tt¯state is discussed) are described by bound states with scalar coupling between their massless constituents and have a structure similar to leptons. However, the scalar Higgs-boson H o corresponds to a state with vector coupling between the elementary constituents. Similar scalar states are expected also in the mass region of the mesons ω (0.782 GeV) - Υ ( 9.46 GeV). The underlying calculations can be run on line using the Web-address https://h2909473.stratoserver.net.
文摘The current journal is mainly focused in zoological systematics.According to Systematics Agenda 2000(1994),systematics is the science built on the following tasks:Taxonomy-the science of discovering,describing,and classifying species or groups of species(together termed taxa);Phylogenetic analysisthe discovery of the evolutionary relationships among a group of species;and Classification-the grouping of species,ultimately on the basis of evolutionary relationships.
文摘The current journal is mainly focused in zoological systematics.According to Systematics Agenda 2000(1994),systematics is the science built on the following tasks:Taxonomy-the science of discovering,describing,and classifying species or groups of species(together termed taxa);Phylogenetic analysisthe discovery of the evolutionary relationships among a group of species;and Classificationthe grouping of species,ultimately on the basis of evolutionary relationships.
文摘The current journal is mainly focused in zoological systematics.According to Systematics Agenda 2000(1994),systematics is the science built on the following tasks:Taxonomy-the science of discovering,describing,and classifying species or groups of species(together termed taxa);Phylogenetic analysis-the discovery of the evolutionary relationships among a group of species;and Classification-the grouping of species,ultimately on the basis of evolutionary relationships.
文摘Our knowledge of renal cell carcinoma(RCC) is rapidly expanding. For those who diagnose and treat RCC, it is important to understand the new developments. In recent years, many new renal tumors have been described and defined, and our understanding of the biology and clinical correlates of these tumors is changing. Evolving concepts in Xp11 translocation carcinoma, mucinous tubular and spindle cell carcinoma, multilocular cystic clear cell RCC, and carcinoma associated with neuroblastoma are addressed within this review. Tubulocystic carcinoma, thyroid-like follicular carcinoma of kidney, acquired cystic disease-associated RCC, and clear cell papillary RCC are also described. Finally, candidate entities, including RCC with t(6;11) translocation, hybrid oncocytoma/chromophobe RCC, hereditary leiomyomatosis and RCC syndrome, and renal angiomyoadenomatous tumor are reviewed. Knowledge of these new entities is important for diagnosis, treatment and subsequent prognosis. This review provides a targeted summary of new developments in RCC.
基金Project supported by the Natural Science Foundation of AnhuiProvince (No. 050430502) and Education Department of AnhuiProvince (No. 2004kj045), China
文摘Twenty-three temperate China species of Lachnum, Lachnum abnorme, L. angustum, L. brevipilosum, L. calosporum, L. calyculiforme, L. carneolum, L. ciliare, L. controversum, L. flavidulum, L. cf. fushanese, L. indicum, L. kumaonicum, L. lushanese, L. minutum, L. montanum, L. cf. pteridophyllum, L. pygmaeum, L. sclerotii var. sclerotii, L. sclerotii var. sichuanense, L. subpygmeaum, L. tenuissimum, L. virgineum and L. willisii are reported, whose main characteristics are given in a formula of the described species, some of which are discussed below.
文摘The paper searched for raw data about wild-caught fish, where a sigmoidal growth function described the mass growth significantly better than non-sigmoidal functions. Specifically, von Bertalanffy’s sigmoidal growth function (metabolic exponent-pair a = 2/3, b = 1) was compared with unbounded linear growth and with bounded exponential growth using the Akaike information criterion. Thereby the maximum likelihood fits were compared, assuming a lognormal distribution of mass (i.e. a higher variance for heavier animals). Starting from 70+ size-at-age data, the paper focused on 15 data coming from large datasets. Of them, six data with 400 - 20,000 data-points were suitable for sigmoidal growth modeling. For these, a custom-made optimization tool identified the best fitting growth function from the general von Bertalanffy-Pütter class of models. This class generalizes the well-known models of Verhulst (logistic growth), Gompertz and von Bertalanffy. Whereas the best-fitting models varied widely, their exponent-pairs displayed a remarkable pattern, as their difference was close to 1/3 (example: von Bertalanffy exponent-pair). This defined a new class of models, for which the paper provided a biological motivation that relates growth to food consumption.
文摘Background liac arterial fibromuscular dysplasia(FMD)were rarely reported and their demographic,clinical and imaging features have not been precisely described resulting in uncertain therapeutic methods.Methods A literature review was performed using Pubmed,Web of Science and Embase database.Original articles in English published since 1990 with full-text and detailed demographic,clinical,imaging and therapeutic information regarding iliac arterial FMD were included.
基金co-financed by the National Natural Science Foundation of China(21075138)special fund of State Key Joint Laboratory of Environment Simulation and Pollution Control(13K02ESPCT)
文摘Density functional theory（DFT）-B3LYP level with the 6-311G＊＊（d,p） basis set was used to calculate a set of molecular quantum chemical descriptors of 12 chloroanilines. Quantitative structure-activity relationship（QSAR） models of the bioconcentration factors（BCF） of the anilines in fish were established using some of the following calculated descriptors： EHOMO, ENHOMO, ELUMO, ENLUMO, ΔE1（= ELUMO- EHOMO）, ΔE2（= ENLUMO- ENHOMO）, dipole moment（μ）, molecular volume（V）, vibrational energy of 0 K（Ev）, thermodynamic energy（E）, heat capacity（Cv）, entropy（Sm） and the charge of benzene ring（Qph）. Using the variable selection and leaps-and-bounds regression, the quantum chemical descriptors derived directly from the molecular structures were employed to develop a linear QSAR model between the bioconcentration factors（BCF） and two descriptors（Sm, ENHOMO） of 12 chloroanilines. Statistically, the most significant one is a two-parameter linear equation with the correlation coefficient（R^2） of 0.981 and cross-validated correlation coefficient（Rcv^2） of 0.967. The established QSAR model has good stability and predictability based on the results from Rcv2 of leave-one-out cross-validation, AIC, FIT and tα/2. The quantum chemical analyses were performed from two aspects of frontier molecular orbital and entropy. The results show that two structural describers are crucial to the bioconcentration activity of chloroanilines.
基金National Natural Science Foundation of China(90716006, 10902006)Research Fund for the Doctoral Program of Higher Education of China (20091102110015)
文摘The flutter characteristics of an actuator-fin system are investigated with structural nonlinearity and dynamic stiffness of the electric motor. The component mode substitution method is used to establish the nonlinear governing equations in time domain and frequency domain based on the fundamental dynamic equations of the electric motor and decelerator. The existing describing function method and a proposed iterative method are used to obtain the flutter characteristics containing preload freeplay nonlinearity when the control command is zero. A comparison between the results of frequency domain and those of time domain is studied. Simulations are carried out when the control command is not zero and further analysis is conducted when the freeplay angle is changed. The results show that structural nonlinearity and dynamic stiffness have a significant influence on the flutter characteristics. Limit cycle oscillations （LCOs） are observed within linear flutter boundary. The response of the actuator-fin system is related to the initial disturbance. In the nonlinear condition, the amplitude of the control command has an influence on the flutter characteristics.
文摘The COVID-19 pandemic has posed a serious threat to global mental health.Multiple lines of evidence suggest that there is a varying yet considerable increase in mental health issues among the general population and vulnerable groups.12 The aftermath is obscure and speculative from a social,economic,individual and public mental health perspective.Recently published studies support the existence of an emotional epidemic curve,describing a high probability of an increase in the burden of mental health issues in the post-pandemic era.34 Furthermore,previous major public health emergencies showed that more than half of the population devel-oped mental health problems and required mental health intervention.45 There is,therefore,an urgent need to reorganise existing mental health services to address the current unmet needs for mental health and to prepare for future challenges in the postpandemic era in terms of prevention and management.
