Fluid dynamic research on rectangular and trapezoidal fins is aimed at increasing heat transfer by means of large surfaces.The trapezoidal cavity form is compared with its thermal and flow performance,and it is reveal...Fluid dynamic research on rectangular and trapezoidal fins is aimed at increasing heat transfer by means of large surfaces.The trapezoidal cavity form is compared with its thermal and flow performance,and it is revealed that trapezoidal fins tend to be more efficient,particularly when material optimization is critical.Motivated by the increasing need for sustainable energy management,this work analyses the thermal performance of inclined trapezoidal and rectangular porous fins utilising a unique hybrid nanofluid.The effectiveness of nanoparticles in a working fluid is primarily determined by their thermophysical properties;hence,optimising these properties can significantly improve overall performance.This study considers the dispersion of Graphene Oxide(GO)and Molybdenum Disulfide in the base fluid,engine oil.Temperature profiles are analysed by altering the radiative,porosity,wet porous,and angle of inclination parameters.Surface and contour plots are constructed by using the Lobatto IIIa Collocation Method with BVP5C solver in MATLAB and Gradient Descent Optimisation to predict the combined heat transfer rate.According to the study,fluid temperature consistently decreases when the angle of inclination,wet porous parameter,porosity parameter,and radiative parameter increase,suggesting significantly improved heat dissipation.The trapezoidal fin consistently exhibits a superior heat transfer mechanism than a rectangular fin.It is found that the trapezoidal fin transmits heat at a rate that is 0.05%higher than that of the rectangular fin.Validation of the present study is done through the comparison of previous studies.This research provides useful design insights for sophisticated engineering uses,including electrical cooling devices,heat exchangers,radiators,and solar heaters.展开更多
Testicular descent occurs in two consecutive stages:the transabdominal stage and the inguinoscrotal stage.Androgens play a crucial role in the second stage by influencing the development of the gubernaculum,a structur...Testicular descent occurs in two consecutive stages:the transabdominal stage and the inguinoscrotal stage.Androgens play a crucial role in the second stage by influencing the development of the gubernaculum,a structure that pulls the testis into the scrotum.However,the mechanisms of androgen actions underlying many of the processes associated with gubernaculum development have not been fully elucidated.To identify the androgen-regulated genes,we conducted large-scale gene expression analyses on the gubernaculum harvested from luteinizing hormone/choriogonadotropin receptor knockout(Lhcgr KO)mice,an animal model of inguinoscrotal testis maldescent resulting from androgen deficiency.We found that the expression of secreted protein acidic and rich in cysteine(SPARC)-related modular calcium binding 1(Smoc1)was the most severely suppressed at both the transcript and protein levels,while its expression was the most dramatically induced by testosterone administration in the gubernacula of Lhcgr KO mice.The upregulation of Smoc1 expression by testosterone was curtailed by the addition of an androgen receptor antagonist,flutamide.In addition,in vitro studies demonstrated that SMOC1 modestly but significantly promoted the proliferation of gubernacular cells.In the cultures of myogenic differentiation medium,both testosterone and SMOC1 enhanced the expression of myogenic regulatory factors such as paired box 7(Pax7)and myogenic factor 5(Myf5).After short-interfering RNA-mediated knocking down of Smoc1,the expression of Pax7 and Myf5 diminished,and testosterone alone did not recover,but additional SMOC1 did.These observations indicate that SMOC1 is pivotal in mediating androgen action to regulate gubernaculum development during inguinoscrotal testicular descent.展开更多
Sentiment analysis plays an important role in distilling and clarifying content from movie reviews,aiding the audience in understanding universal views towards the movie.However,the abundance of reviews and the risk o...Sentiment analysis plays an important role in distilling and clarifying content from movie reviews,aiding the audience in understanding universal views towards the movie.However,the abundance of reviews and the risk of encountering spoilers pose challenges for efcient sentiment analysis,particularly in Arabic content.Tis study proposed a Stochastic Gradient Descent(SGD)machine learning(ML)model tailored for sentiment analysis in Arabic and English movie reviews.SGD allows for fexible model complexity adjustments,which can adapt well to the Involvement of Arabic language data.Tis adaptability ensures that the model can capture the nuances and specifc local patterns of Arabic text,leading to better performance.Two distinct language datasets were utilized,and extensive pre-processing steps were employed to optimize the datasets for analysis.Te proposed SGD model,designed to accommodate the nuances of each language,aims to surpass existing models in terms of accuracy and efciency.Te SGD model achieves an accuracy of 84.89 on the Arabic dataset and 87.44 on the English dataset,making it the top-performing model in terms of accuracy on both datasets.Tis indicates that the SGD model consistently demonstrates high accuracy levels across Arabic and English datasets.Tis study helps deepen the understanding of sentiments across various linguistic datasets.Unlike many studies that focus solely on movie reviews,the Arabic dataset utilized here includes hotel reviews,ofering a broader perspective.展开更多
An optimal feedback guidance law with disturbance rejection objective is proposed for endoatmospheric powered descent.This guidance law with an affine form is derived by solving a novel problem called Endoatmospheric ...An optimal feedback guidance law with disturbance rejection objective is proposed for endoatmospheric powered descent.This guidance law with an affine form is derived by solving a novel problem called Endoatmospheric Powered Descent Guidance with Disturbance Rejection(Endo-PDG-DR).The key idea of formulating the Endo-PDG-DR problem is dividing disturbances into two parts,modeled and unmodeled disturbances:the modeled disturbance is proactively exploited by augmenting it as a new state of a dynamics model;the unmodeled disturbance is reactively attenuated in terms of its effect on the guidance performance by adjoining a parameterized time-varying quadratic performance index in the proposed optimal guidance problem.A Pseudospectral Differential Dynamic Programming(PDDP)method is developed to solve the Endo-PDG-DR problem,and correspondingly a robust neighboring optimal state feedback law is obtained,which has two synergistic functionalities.One is adaptive optimal steering to accommodate the modeled disturbance,and the other is disturbance attenuation to compensate for the state perturbation effect induced by the unmodeled disturbance.Using the derived feedback guidance law,a disturbance rejection level is quantified,and is correspondingly optimized by designing a quadratic weighting parameter tuning law.The numerical computations of interest are performed within a pseudospectral setting,ensuring polynomial analytical solution,high computational efficiency,and reliable convergence.展开更多
基金supported by the“Regional Innovation System&Education(RISE)”through the Seoul RISE Center,funded by the Ministry of Education(MOE)and the Seoul Metropolitan Government(2025-RISE-01-027-04).
文摘Fluid dynamic research on rectangular and trapezoidal fins is aimed at increasing heat transfer by means of large surfaces.The trapezoidal cavity form is compared with its thermal and flow performance,and it is revealed that trapezoidal fins tend to be more efficient,particularly when material optimization is critical.Motivated by the increasing need for sustainable energy management,this work analyses the thermal performance of inclined trapezoidal and rectangular porous fins utilising a unique hybrid nanofluid.The effectiveness of nanoparticles in a working fluid is primarily determined by their thermophysical properties;hence,optimising these properties can significantly improve overall performance.This study considers the dispersion of Graphene Oxide(GO)and Molybdenum Disulfide in the base fluid,engine oil.Temperature profiles are analysed by altering the radiative,porosity,wet porous,and angle of inclination parameters.Surface and contour plots are constructed by using the Lobatto IIIa Collocation Method with BVP5C solver in MATLAB and Gradient Descent Optimisation to predict the combined heat transfer rate.According to the study,fluid temperature consistently decreases when the angle of inclination,wet porous parameter,porosity parameter,and radiative parameter increase,suggesting significantly improved heat dissipation.The trapezoidal fin consistently exhibits a superior heat transfer mechanism than a rectangular fin.It is found that the trapezoidal fin transmits heat at a rate that is 0.05%higher than that of the rectangular fin.Validation of the present study is done through the comparison of previous studies.This research provides useful design insights for sophisticated engineering uses,including electrical cooling devices,heat exchangers,radiators,and solar heaters.
基金supported in part by the Department of OB/GYN research funds(University of Louisville,Louisville,KY,USA)Jilin Province Health Technology Capability Enhancement funds(No.2022JC055).
文摘Testicular descent occurs in two consecutive stages:the transabdominal stage and the inguinoscrotal stage.Androgens play a crucial role in the second stage by influencing the development of the gubernaculum,a structure that pulls the testis into the scrotum.However,the mechanisms of androgen actions underlying many of the processes associated with gubernaculum development have not been fully elucidated.To identify the androgen-regulated genes,we conducted large-scale gene expression analyses on the gubernaculum harvested from luteinizing hormone/choriogonadotropin receptor knockout(Lhcgr KO)mice,an animal model of inguinoscrotal testis maldescent resulting from androgen deficiency.We found that the expression of secreted protein acidic and rich in cysteine(SPARC)-related modular calcium binding 1(Smoc1)was the most severely suppressed at both the transcript and protein levels,while its expression was the most dramatically induced by testosterone administration in the gubernacula of Lhcgr KO mice.The upregulation of Smoc1 expression by testosterone was curtailed by the addition of an androgen receptor antagonist,flutamide.In addition,in vitro studies demonstrated that SMOC1 modestly but significantly promoted the proliferation of gubernacular cells.In the cultures of myogenic differentiation medium,both testosterone and SMOC1 enhanced the expression of myogenic regulatory factors such as paired box 7(Pax7)and myogenic factor 5(Myf5).After short-interfering RNA-mediated knocking down of Smoc1,the expression of Pax7 and Myf5 diminished,and testosterone alone did not recover,but additional SMOC1 did.These observations indicate that SMOC1 is pivotal in mediating androgen action to regulate gubernaculum development during inguinoscrotal testicular descent.
文摘Sentiment analysis plays an important role in distilling and clarifying content from movie reviews,aiding the audience in understanding universal views towards the movie.However,the abundance of reviews and the risk of encountering spoilers pose challenges for efcient sentiment analysis,particularly in Arabic content.Tis study proposed a Stochastic Gradient Descent(SGD)machine learning(ML)model tailored for sentiment analysis in Arabic and English movie reviews.SGD allows for fexible model complexity adjustments,which can adapt well to the Involvement of Arabic language data.Tis adaptability ensures that the model can capture the nuances and specifc local patterns of Arabic text,leading to better performance.Two distinct language datasets were utilized,and extensive pre-processing steps were employed to optimize the datasets for analysis.Te proposed SGD model,designed to accommodate the nuances of each language,aims to surpass existing models in terms of accuracy and efciency.Te SGD model achieves an accuracy of 84.89 on the Arabic dataset and 87.44 on the English dataset,making it the top-performing model in terms of accuracy on both datasets.Tis indicates that the SGD model consistently demonstrates high accuracy levels across Arabic and English datasets.Tis study helps deepen the understanding of sentiments across various linguistic datasets.Unlike many studies that focus solely on movie reviews,the Arabic dataset utilized here includes hotel reviews,ofering a broader perspective.
基金co-supported by the National Natural Science Foundation of China(No.62103014)。
文摘An optimal feedback guidance law with disturbance rejection objective is proposed for endoatmospheric powered descent.This guidance law with an affine form is derived by solving a novel problem called Endoatmospheric Powered Descent Guidance with Disturbance Rejection(Endo-PDG-DR).The key idea of formulating the Endo-PDG-DR problem is dividing disturbances into two parts,modeled and unmodeled disturbances:the modeled disturbance is proactively exploited by augmenting it as a new state of a dynamics model;the unmodeled disturbance is reactively attenuated in terms of its effect on the guidance performance by adjoining a parameterized time-varying quadratic performance index in the proposed optimal guidance problem.A Pseudospectral Differential Dynamic Programming(PDDP)method is developed to solve the Endo-PDG-DR problem,and correspondingly a robust neighboring optimal state feedback law is obtained,which has two synergistic functionalities.One is adaptive optimal steering to accommodate the modeled disturbance,and the other is disturbance attenuation to compensate for the state perturbation effect induced by the unmodeled disturbance.Using the derived feedback guidance law,a disturbance rejection level is quantified,and is correspondingly optimized by designing a quadratic weighting parameter tuning law.The numerical computations of interest are performed within a pseudospectral setting,ensuring polynomial analytical solution,high computational efficiency,and reliable convergence.
