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Surface element design of nanomaterials considering surface curvature dependence
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作者 Yongchao Zhang Lian Wang +2 位作者 Fangxin Wang Bin Li Xiaofan Gou 《Acta Mechanica Sinica》 2025年第1期42-53,共12页
Nanomaterials have garnered recognition for their notable surface effects and demonstration of superior mechanical properties.Previous studies on the surface effects of nanomaterials,employing the finite element metho... Nanomaterials have garnered recognition for their notable surface effects and demonstration of superior mechanical properties.Previous studies on the surface effects of nanomaterials,employing the finite element method,often relied on simplified twodimensional models due to theoretical complexities.Consequently,these simplified models inadequately represent the mechanical properties of nanomaterials and fail to capture the substantial impact of surface effects,particularly the curvature dependence of nanosurfaces.This study applies the principle of minimum energy and leverages the Steigmann-Ogden surface theory of nanomaterials to formulate a novel finite element surface element that comprehensively accounts for surface effects.We conducted an analysis of the stress distribution and deformation characteristics of four typical 2D and 3D nanomaterial models.The accuracy of the developed surface element and finite element calculation method was verified through comparison with established references.The resulting finite element model provides a robust and compelling scientific approach for accurately predicting the mechanical performance of nanomaterials. 展开更多
关键词 NANOMATERIALS Surface effect Surface element curvature dependence Finite element method
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Exploring the multiplicity dependence of the flavor hierarchy for hadron production in high-energy pp collisions
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作者 Ao-Gui Zhang Xin-Ye Peng Liang Zheng 《Nuclear Science and Techniques》 2025年第8期126-137,共12页
In this study,we performed a systematic analysis of the multiplicity dependence of hadron production at mid-rapidity(|y|<0.5),ranging from the light to the charm sector in proton-proton(pp)collisions at√s=13 TeV.T... In this study,we performed a systematic analysis of the multiplicity dependence of hadron production at mid-rapidity(|y|<0.5),ranging from the light to the charm sector in proton-proton(pp)collisions at√s=13 TeV.This study used a multi-phase transport(AMPT)model coupled with PYTHIA8 initial conditions.We investigated the baryon-to-meson and the strange-to-non-strange meson ratios varying with the charged particle density.By tuning the coalescence parameters,the AMPT model provides a reasonable description of the experimental data for the inclusive production of both light and charm hadrons,comparable to the string fragmentation model calculations with color reconnection effects.Additionally,we analyzed the relative production of hadrons by examining the self-normalized particle ratios as a function of the charged hadron density.Our findings suggest that parton evolution effects and the coalescence hadronization process in the AMPT model result in a strong flavor hierarchy in the multiplicity dependence of the baryon-to-meson ratio.Furthermore,our investigation of the p_(T) differential double ratio of the baryon-to-meson fraction between high-and low-multiplicity events revealed distinct modifications to the flavor associated baryon-to-meson ratio p_(T) shape in high-multiplicity events when comparing the coalescence hadronization model to the color reconnection model.These observations highlight the importance of understanding the hadronization process in high-energy pp collisions through comprehensive multiplicity-dependent multi-flavor analysis. 展开更多
关键词 Heavy flavor Multiplicity dependence Small system AMPT
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Acupuncture with different frequencies for tobacco dependence:a randomized controlled trial
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作者 CHEN Shumin LIU Zhenyu +4 位作者 JI Jia CHANG Jin LI Zhihua WANG Yingying YANG Jinsheng 《Journal of Traditional Chinese Medicine》 2025年第3期651-659,共9页
OBJECTIVE:To observe the effect of different acupuncture frequencies on the abstinence rate which could be used as a reference for optimizing acupuncture cessation programs.METHODS:From July 2018 to June 2022,a total ... OBJECTIVE:To observe the effect of different acupuncture frequencies on the abstinence rate which could be used as a reference for optimizing acupuncture cessation programs.METHODS:From July 2018 to June 2022,a total of 220 smokers were recruited based on inclusion criteria and randomly divided into the high-frequency acupuncture group(HF group,n=110):5 times a week from the 1st to the 4th week,from weeks 5 to 8,three times a week and the low-frequency acupuncture group(LF group,n=110):3 times a week from the 1st to the 4th week,from weeks 5 to 8,twice a week,then treated for 8 weeks and followup at 1 month in Beijing.RESULTS:In total,162 subjects completed the whole study with a drop-out rate of 20.45%.The expiratory CO point abstinence rate was HF group 53/110(48.18%)vs LF group 41/110(37.27%)in Week 8(P=0.102)and HF group 46/110(41.82%)vs LF group 45/110(40.91%)in Week 12(P=0.891)and the HF acupuncture and LF acupuncture were nearly equal in the 8-week abstinence rate.In addition,both HF and LF acupuncture significantly reduced Fagerstr?m test for nicotine dependence scale(FTND)scores(P<0.05),Minnesota nicotine withdrawal scale(MNWS)scores(P<0.05),and Brief Questionnaire of Smoking Urges scale(QSU-Brief)scores(P<0.05),but HF acupuncture showed some superiority over LF acupuncture in relieving patients'smoking cravings(P<0.05).CONCLUSIONS:The study initially showed that both high-frequency acupuncture and low-frequency acupuncture treatment were safe and effective on smoking cessation for 8 weeks,but high-frequency acupuncture was advantageous in reducing smoking cravings.More accurate acupuncture frequency needs to be validated through larger clinical studies to optimize acupuncture smoking cessation programs. 展开更多
关键词 ACUPUNCTURE acupuncture frequency tobacco dependence smoking cessation
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Kinetic Analysis of pH Dependence in Electrocatalytic Reactions:Strategy and Pitfall
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作者 Yifei Xu Bingjun Xu 《Carbon and Hydrogen》 2025年第3期320-327,共8页
Electrocatalysis has been investigated as a promising strategy to utilize green electricity to produce renewable fuels,valuable chemicals,and treat pollutants.Electrode kinetic analysis is a potent technique in interr... Electrocatalysis has been investigated as a promising strategy to utilize green electricity to produce renewable fuels,valuable chemicals,and treat pollutants.Electrode kinetic analysis is a potent technique in interrogating reaction mechanisms and evaluating the electrocatalysts.Electron transfer(ET)and proton‐coupled electron transfer(PCET)processes are widely present in reaction networks of electrocatalysis.pH dependence of the kinetics is frequently employed to evaluate whether an elementary step involves proton participation,which is determined by both the reversibility and the specific reactants of electrode reactions.In this article,we discuss the pH dependence of two widely used formulations of the Butler–Volmer kinetics for a model PCET step and highlight a potential pitfall in kinetic analysis.This work aims to provide guiding principles for distinguishing ET and PCET steps via kinetic measurements in electrolytes in a broad range pH values. 展开更多
关键词 equilibrium potential kinetic analysis OVERPOTENTIAL pH dependence
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A bibliometric analysis of the relationship between the brain-derived neurotrophic factor and cognitive dysfunction due to alcohol dependence syndrome
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作者 Lin He Yan Deng +3 位作者 Xin Lyu Rongzhen Cui Jie Han Le Zhang 《Journal of Translational Neuroscience》 2025年第1期30-38,共9页
Objective:To evaluate the global liter-ature output on the relationship between brain-derived neurotrophic factor(BDNF)and cognitive function in al-cohol dependence syndrome using bibliometric methods and explore the ... Objective:To evaluate the global liter-ature output on the relationship between brain-derived neurotrophic factor(BDNF)and cognitive function in al-cohol dependence syndrome using bibliometric methods and explore the status and trends in this field.Method:The literature on the application of BDNF in cognitive impairment caused by alcohol dependence syndrome published from 1995 to 2023 were retrieved from Web of Science,and the relevant information(publication characteristics,country and institution,author,number of publications,citation,journal and research field,corresponding author,key words,etc.)was recorded.The bibliometrix R package was used for quantitative and qualitative analysis of publication output and author contributions.Result:A total of 99 articles were included.The overall number of publications in this field has increased over time.The countries and institutions that contributed the most to the field were the United States and the Academy of Medical Sciences of Iranian universities,respectively.Most of the authors were from the United States,followed by Spain,China,and Iran.Ceccanti M,Fiore M were the most productive authors.Publications with Ceccanti M had the highest h-index.The most cited reference author is Haenninen H(227 citations),and the number one published journal is Alcohol.Most articles were published in 2020(n=12)and 2022(n=11),followed by 2019 and 2021(n=10).The corresponding author has the largest number of publications from the United States,and more publications from a single country tend to have more cooperation from other countries.BDNF and alcohol appeared more frequently in various keyword clouds.However,significant differences remained in the author keyword cloud,keyword plus word cloud,and paper topic word cloud.Conclusion:BDNF has great potential in the application of cognitive dysfunction caused by alcohol dependence syndrome.Bibliometric methods and data visualization techniques can help understand the current state of research progress and enable relevant scholars and practitioners to predict the development trends in this field. 展开更多
关键词 alcohol dependence syndrome cognitive impairment brain-derived neurotrophic factor bibliometric analysis
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From fledging to independence:Post-fledging movements and space use of the Crested Ibis(Nipponia nippon)
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作者 Yu Lei Xianglong Xu +6 位作者 Yuanxing Ye Chao Wang Baoping Qing Wenbin Duan Jiaqi Yan Yongjie Huang Changqing Ding 《Avian Research》 2025年第3期362-371,共10页
The post-fledging period, extending from fledging to independence, is a crucial life stage characterized by high mortality due to fledglings' limited mobility and inexperience. During this stage, fledglings gradua... The post-fledging period, extending from fledging to independence, is a crucial life stage characterized by high mortality due to fledglings' limited mobility and inexperience. During this stage, fledglings gradually increase their mobility, leave their parents, disperse from their natal site, and respond to the challenges of new environments. Characterizing these post-fledging movements and space use is essential for understanding juvenile survival strategies and devising targeted conservation measures. The Crested Ibis (Nipponia nippon), an endangered species and a highly protected animals at the national level in China, has seen limited research on its post-fledging movements and space use. From 2015 to 2023, we utilized biologgers, combined with field surveys, to study the movement and space use characteristics of 37 fledglings in Hanzhong City, Shaanxi Province, China, over a two-month post-fledging period. We quantified changes in activity levels (based on overall dynamic body acceleration), independence timing, onset of post-fledging dispersal, habitat selection, and daily activity rhythms after independence. Our results revealed individuals began independent living 26.23 ± 2.34 days post-fledging and onset of dispersal at 25.58 ± 2.33 days, with a range area at the natal of 2.08 ± 0.56 km^(2). The initial 30 days post-fledging are characterized as an ontogenetic phase marked by a rapid increase in body activity level. Fledglings preferred paddy fields during the independent period rather than the forests they relied on before independence. Interestingly, the daily activity rhythm, particularly foraging behavior, peaked at noon—contrasting with the expected morning and evening activity peaks—likely as an adaptation to avoid periods of peak human activity. Additionally, drowning, collisions, and predation in paddy fields are noteworthy causes of fledgling mortality. Consequently, we recommend protecting a 2-km^(2) area around the nest site for at least two-month post-fledging, implementing safety measures around power lines and cesspools. Additionally, reducing human disturbances near foraging habitats and expanding space within paddy fields would help mitigate survival pressures on fledglings. 展开更多
关键词 Behavioral development hypothesis Daily activity rhythms Dependent period Habitat selection Physical mobility development Post-fledging dispersal
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交叉电项针治疗卒中相关性肺炎呼吸机依赖患者的临床疗效
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作者 蔡国锋 孙波 +8 位作者 庄哲 贾坤平 王虹 郭祀慧 崔成 高子茵 吴珍琦 马兴武 孙满超 《中国急救医学》 2026年第1期50-55,共6页
目的观察交叉电项针对卒中相关性肺炎呼吸机依赖患者脱机的影响。方法将90例卒中相关性肺炎呼吸机依赖患者采用随机数字表法分为项针组、电项针组和交叉电项针组,每组30例。三组在相同的基础针灸、对症治疗及基础护理的基础上,分别采用... 目的观察交叉电项针对卒中相关性肺炎呼吸机依赖患者脱机的影响。方法将90例卒中相关性肺炎呼吸机依赖患者采用随机数字表法分为项针组、电项针组和交叉电项针组,每组30例。三组在相同的基础针灸、对症治疗及基础护理的基础上,分别采用项针、电项针和交叉电项针三种不同的针刺治疗方案,共治疗28 d。对三组膈肌呼吸变异度(TFdi)、动脉氧分压(PaO_(2))、动脉二氧化碳分压(PaCO_(2))、肺炎严重指数(PSI)、格拉斯哥昏迷评分(GCS评分)和脱机成功率进行比较,探讨三组治疗方案对卒中相关性肺炎呼吸机依赖患者的治疗效果。结果三组组内治疗前后比较,TFdi、PaO_(2)、PaCO_(2)、PSI、GCS等相关指标均有改善(P<0.05);治疗后三组TFdi、PaO_(2)、PaCO_(2)、PSI、GCS等指标改善程度,交叉电项针组>电项针组>项针组(P<0.05)。交叉电项针组脱机成功率86.67%,电项针组脱机成功率66.67%,项针组脱机成功率50.00%,结合各组治疗后各项指标及最终脱机成功率,交叉电项针组治疗效果优于电项针组和项针组(P<0.05)。结论交叉电项针治疗能改善卒中相关性肺炎呼吸机依赖患者的TFdi、PaO_(2)、PaCO_(2)、PSI、GCS等相关指标,提高脱机成功率。 展开更多
关键词 交叉电项针 卒中相关性肺炎 呼吸机依赖
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Molecular dynamics study on temperature and strain rate dependences of mechanical tensile properties of ultrathin nickel nanowires 被引量:3
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作者 王卫东 易成龙 樊康旗 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2013年第11期3353-3361,共9页
Based on the EAM potential, a molecular dynamics study on the tensile properties of ultrathin nickel nanowires in the (100〉 orientation with diameters of 3.94, 4.95 and 5.99 nm was presented at different temperature... Based on the EAM potential, a molecular dynamics study on the tensile properties of ultrathin nickel nanowires in the (100〉 orientation with diameters of 3.94, 4.95 and 5.99 nm was presented at different temperatures and strain rates. The temperature and strain rate dependences of tensile properties were investigated. The simulation results show that the elastic modulus and the yield strength are gradually decreasing with the increase of temperature, while with the increase of the strain rate, the stress--strain curves fluctuate more intensely and the ultrathin nickel nanowires rupture at one smaller and smaller strain. At an ideal temperature of 0.01 K, the yield strength of the nanowires drops rapidly with the increase of strain rate, and at other temperatures the strain rate has a little influence on the elastic modulus and the yield strength. Finally, the effects of size on the tensile properties of ultrathin nickel nanowires were briefly discussed. 展开更多
关键词 ultrathin nickel nanowires temperature dependence strain rate dependence tensile properties molecular dynamics simulation
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钢桥板单元分布式柔性作业车间成组调度
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作者 朱斌 马骁 +1 位作者 李稷丰 雷景媛 《郑州大学学报(工学版)》 北大核心 2026年第1期41-48,共8页
针对钢桥板单元生产速度过慢会直接制约桥梁工程建设周期的问题,在考虑钢桥板单元的加工工艺路线和生产特点的同时,以最小化最大完工时间为目标,建立了考虑顺序相关作业切换时间和运输时间,面向钢桥板单元加工的分布式柔性作业车间成组... 针对钢桥板单元生产速度过慢会直接制约桥梁工程建设周期的问题,在考虑钢桥板单元的加工工艺路线和生产特点的同时,以最小化最大完工时间为目标,建立了考虑顺序相关作业切换时间和运输时间,面向钢桥板单元加工的分布式柔性作业车间成组调度(DFJGSPST)模型,并提出了基于三层编码的记忆混合遗传禁忌搜索算法(MGATS)。为验证数学模型和智能算法的可行性,以某钢桥板单元生产为例,建立了包括4种板单元组和15台机器的DFJGSPST模型,通过相应的测试算例进行实验验证,并与其他智能算法进行比较分析。实验结果表明:所提的MGATS的相对百分比差异(RPD)的均值为2.74%,低于遗传算法(GA)的3.99%和混合遗传禁忌搜索算法(GATS)的3.13%。MGATS的成功率(SR)为0.15,高于GATS和GA,验证了MGATS在求解DFJGSPST模型中的稳定性和鲁棒性。 展开更多
关键词 钢桥板单元 柔性作业车间 成组调度 顺序相关 运输时间 混合遗传禁忌搜索算法
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MOLECULAR WEIGHT DEPENDENCE OF CRYSTAL PATTERN TRANSITIONS OF POLY(ETHYLENE OXIDE) 被引量:1
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作者 Guo-liang Zhang Liu-xin Jin +2 位作者 Ping Zheng 王维 Xiao-jing Wen 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2013年第5期798-808,共11页
Crystal patterns in ultrathin films of six poly(ethylene oxide) fractions with molecular weights from 25000 to 932000 g/mol were characterized within crystallization temperature range from 20 ℃to 60℃. Labyrinthine... Crystal patterns in ultrathin films of six poly(ethylene oxide) fractions with molecular weights from 25000 to 932000 g/mol were characterized within crystallization temperature range from 20 ℃to 60℃. Labyrinthine, dendritic and faceted crystal patterns were observed in different temperature ranges, and then labyrinthine-to-dendritic and dendritic-to- faceted transition temperatures T_L-D and T_D-F were quantitatively identified. Their molecular weight dependences are T_L-D(M_w) = T_L-D(∞) -K_L-D/M_w, where T_L-D(∞) = 38.2 ℃ and K_L-D = 253000 ℃.g/mol and T_D-F(M_w) = T_D-F(∞) -K_D-F/M_w, where T_D-F(∞) = 54.7 ℃ and K_D-F= 27000 ℃.g/mol. Quasi two-dimensional blob models were proposed to provide empirical explanations of the molecular weight dependences. The labyrinthine-to-dendritic transition is attributed to a molecular diffusion process change from a local-diffusion to diffusion-limited-aggregation (DLA) and a polymer chain with M_w ≈253000 g/mol within a blob can join crystals independently. The dendritic-to-faceted transition is attributed to a turnover of the pattern formation mechanism from DLA to crystallization control, and a polymer chain with a M_w ≈27000 g/tool as an independent blob crosses to a depletion zone to join crystals. These molecular weight dependences reveal a macromolecular effect on the crystal pattern formation and selection of crystalline polymers. 展开更多
关键词 Poly(ethylene oxide) CRYSTALLIZATION Pattern formation TRANSITION Molecular weight dependence.
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Temperature Dependence of the Energy-Band Structure for the Holstein Molecular-Crystal Model
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作者 李德俊 彭金璋 +1 位作者 米贤武 唐翌 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2008年第5期845-850,共6页
We study the influences of the temperature on the energy-band structure for the Holstein molecular-crystal model. We show that the energy-band width and the energy-gap width of a solid are relevant to both the interac... We study the influences of the temperature on the energy-band structure for the Holstein molecular-crystal model. We show that the energy-band width and the energy-gap width of a solid are relevant to both the interaction between an electron and thermal phonons and to thermal expansion. For a one-dimensional Li atom lattice chain, under the chosen parameters,the width of the ls and 2s energy bands narrows as the temperature increases and the energy-gap width between the two bands widens. These results agree qualitatively with those observed experimentally. Studying temperature dependence of the energy-band structure is of great importance for understanding optical and transporting characteristics of a solid. 展开更多
关键词 temperature dependence energy-band structure thermal phonon thermal expansion
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Temperature Dependence of Performance of 6H-SiC Unipolar Power Devices
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作者 何进 张兴 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2001年第10期1235-1239,共5页
The temperature dependence of some performance of 6H SiC unipolar power devices is analyzed theoretically.By employing the temperature dependent ionization coefficient and mobility of a silicon carbide,the analytica... The temperature dependence of some performance of 6H SiC unipolar power devices is analyzed theoretically.By employing the temperature dependent ionization coefficient and mobility of a silicon carbide,the analytical expressions of the temperature dependent performance,such as breakdown characteristics and on resistance of 6H SiC unipolar power devices are derived in a closed form.The analytical results are compared with the experimental results,with good accordance found in the breakdown characteristics. 展开更多
关键词 wide band gap semiconductor devices 6H SiC impact ionization coefficient avalanche breakdown on resistance temperature dependence of performance
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Temperature dependence of magnetization reversal mechanism in CoNi/CoO bilayers
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作者 宋金涛 袁淑娟 《Journal of Shanghai University(English Edition)》 CAS 2007年第6期562-565,共4页
Exchange coupling and magfietization reversal mechanism in two series of CoxNil-x/CoO (30 nm) (x=0.2 and 0.4) bilayers are studied by vector magnetometer. Two components of magnetization are measured parallel and ... Exchange coupling and magfietization reversal mechanism in two series of CoxNil-x/CoO (30 nm) (x=0.2 and 0.4) bilayers are studied by vector magnetometer. Two components of magnetization are measured parallel and perpendicular to the applied field. At low temperatures, coercivity Hc oc (tFM)^-n, n = 1.5 and 1.38 for x = 0.2 and 0.4, respectively, in agreement with the random field model. At room temperature, the coercivity is nearly proportional to the inverse FM layer thickness. In addition to the exchange field and the coercivity, the characteristic of the magnetization reversal mechanism was found to change with temperature. At temperatures below 180 K, magnetization reversal process along the unidirectional axis is accompanied only by nucleation and pinning of domain wall while magnetization rotation is also involved at high temperatures. 展开更多
关键词 exchange coupling BILAYER magnetization reversal temperature dependence.
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二陈汤干预ATG7/FTH1通路改善痰湿型多囊卵巢综合征大鼠卵泡功能的研究
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作者 吕小娇 柏子寒 +5 位作者 马妍 陈巍 曲扬 隋国媛 尚冰 丛培玮 《中国全科医学》 北大核心 2026年第5期649-655,共7页
背景多囊卵巢综合征(PCOS)是一类尚无明确病因的妇科内分泌代谢性疾病,患病率日渐年轻化、普遍化,因此研究PCOS分子生物学层面的发病机制,可为临床治疗提供相关依据,守护女性健康。目的以中医学“痰湿”体质导致不孕的理论为依据,探讨... 背景多囊卵巢综合征(PCOS)是一类尚无明确病因的妇科内分泌代谢性疾病,患病率日渐年轻化、普遍化,因此研究PCOS分子生物学层面的发病机制,可为临床治疗提供相关依据,守护女性健康。目的以中医学“痰湿”体质导致不孕的理论为依据,探讨二陈汤对PCOS卵巢颗粒细胞线粒体自噬依赖性铁死亡的改善作用。方法辽宁中医药大学实验动物中心提供SPF级实验室及32只SD雌性大鼠,适应性喂养1周后,随机将32只大鼠分为对照组(n=10)和模型组(n=22)。对照组给予普通维持饲料全程喂养,共12周;模型组全程给予高脂饲料喂养,造模期间每日给予来曲唑溶液灌胃。造模完毕选取动情周期紊乱的模型组大鼠作为治疗组(n=12),每日给予二陈汤煎剂灌胃,连续4周进行治疗。取材后对大鼠卵巢进行HE染色,观察病理变化,采用透射电镜拍摄3组大鼠卵巢颗粒细胞线粒体形态学变化,采用Western Blotting法检测大鼠卵巢颗粒细胞自噬相关基因7(ATG7)、P62、自噬相关蛋白1(Beclin1)、微管相关蛋白1轻链3-Ⅰ(LC3-Ⅰ)、微管相关蛋白1轻链3-Ⅱ(LC3-Ⅱ)、铁蛋白重链1(FTH1)、线粒体呼吸链组装蛋白2(ISCU2)蛋白水平变化。采用Oxygraph-2k线粒体功能测定系统检测卵巢颗粒细胞线粒体耗氧率变化。结果模型组大鼠卵巢囊性卵泡增多,黄体减少并且卵巢颗粒细胞线粒体出现自噬与铁死亡现象,治疗组治疗后形态部分恢复。与对照组相比,模型组ATG7、P62、Beclin1、LC3-Ⅱ蛋白水平升高(P<0.05),LC3-Ⅱ/LC3-Ⅰ升高(P<0.05),LC3-Ⅰ、FTH1、ISCU2蛋白水平降低(P<0.05);与模型组相比,治疗组ATG7、P62、Beclin1、LC3-Ⅱ蛋白水平降低(P<0.05),LC3-Ⅱ/LC3-Ⅰ降低(P<0.05),FTH1蛋白水平升高(P<0.05)。三组电子传递系统(ETS)、线粒体复合体Ⅰ(CⅠ)、线粒体复合体Ⅱ(CⅡ)耗氧率比较,差异有统计学意义(P<0.05);其中模型组ETS、CⅠ、CⅡ耗氧率低于对照组,治疗组ETS、CⅠ、CⅡ耗氧率高于模型组,差异均有统计学意义(P<0.05)。结论二陈汤通过ATG7/FTH1通路逆转卵巢颗粒细胞自噬依赖性铁死亡,改善痰湿型PCOS大鼠的卵泡功能。 展开更多
关键词 多囊卵巢综合征 二陈汤 自噬依赖性铁死亡 痰湿不孕 线粒体
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The Use of Field Dependence/Independence in Language Acquisition
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作者 操龙升 《海外英语》 2012年第20期114-115,共2页
Field dependence/independence in Language Acquisition are discussed by many language learners.In this article,we will mainly focus on talking about the cognitive style,including the concept of Field-dependence/indepen... Field dependence/independence in Language Acquisition are discussed by many language learners.In this article,we will mainly focus on talking about the cognitive style,including the concept of Field-dependence/independence,their character istics and differences and functions in language acquisition. 展开更多
关键词 FIELD dependence/independence LANGUAGE ACQUISITION
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基于“痰湿不孕”探讨PCOS自噬依赖性铁死亡发病机制及用药原则
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作者 吕小娇 马妍 +5 位作者 凌娜 曲扬 尚冰 王蔚 陈巍 丛培玮 《辽宁中医药大学学报》 2026年第1期169-173,共5页
多囊卵巢综合征(Polycystic ovary syndrome,PCOS)是一种常见的妇科内分泌代谢性疾病,受多种因素影响,目前尚无明确病因。基于“痰湿不孕”理论,中医认为痰湿阻塞胞宫是痰湿型PCOS的关键发病因素,研究发现,痰湿可诱导卵巢颗粒细胞发生... 多囊卵巢综合征(Polycystic ovary syndrome,PCOS)是一种常见的妇科内分泌代谢性疾病,受多种因素影响,目前尚无明确病因。基于“痰湿不孕”理论,中医认为痰湿阻塞胞宫是痰湿型PCOS的关键发病因素,研究发现,痰湿可诱导卵巢颗粒细胞发生过度自噬,降解抗铁细胞凋亡调节因子,提升铁死亡的易感性。越来越多的研究将铁死亡视为一种自噬依赖性的细胞死亡形式——自噬依赖性铁死亡,几种选择性自噬包括铁蛋白自噬、脂肪自噬、线粒体自噬等,而自噬异常介导的铁死亡发生可继发细胞线粒体损伤,氧化应激异常,进而引发体内能量代谢紊乱,造成机体糖脂代谢异常,上述机制亦可通过相互作用,阻碍卵泡发育,最终导致PCOS发生,影响胞宫生殖功能。文章将通过阐释不同类型自噬在痰湿型PCOS这一病理过程中引起卵巢颗粒细胞铁死亡的发病机制,及分析临床治疗PCOS的燥湿化痰经典方剂——二陈汤的用药原则展开论述,同时总结了其他传统中医疗法在PCOS临床治疗中的优势,以期为中医治疗痰湿型PCOS提供可靠的科学依据,守护女性健康。 展开更多
关键词 多囊卵巢综合征 痰湿不孕 自噬依赖性铁死亡 二陈汤
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EXACT CONTROLLABILITY AND CONTINUOUS DEPENDENCE OF FRACTIONAL NEUTRAL INTEGRO-DIFFERENTIAL EQUATIONS WITH STATE-DEPENDENT DELAY 被引量:17
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作者 马和平 刘斌 《Acta Mathematica Scientia》 SCIE CSCD 2017年第1期235-258,共24页
In the present paper,with the help of the resolvent operator and some analytic methods,the exact controllability and continuous dependence are investigated for a fractional neutral integro-differential equations with ... In the present paper,with the help of the resolvent operator and some analytic methods,the exact controllability and continuous dependence are investigated for a fractional neutral integro-differential equations with state-dependent delay.As an application,we also give one example to demonstrate our results. 展开更多
关键词 CONTROLLABILITY continuous dependence fractional neutral integro-differentialequations state-dependent delay resolvent operator
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Time-variant fragility analysis of the bridge system considering time-varying dependence among typical component seismic demands 被引量:10
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作者 Song Shuai Qian Yongjiu +2 位作者 Liu Jing Xie Xiaorui Wu Gang 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2019年第2期363-377,共15页
This paper presents a copula technique to develop time-variant seismic fragility curves for corroded bridges at the system level and considers the realistic time-varying dependence among component seismic demands. Bas... This paper presents a copula technique to develop time-variant seismic fragility curves for corroded bridges at the system level and considers the realistic time-varying dependence among component seismic demands. Based on material deterioration mechanisms and incremental dynamic analysis, the time-evolving seismic demands of components were obtained in the form of marginal probability distributions. The time-varying dependences among bridge components were then captured with the best fitting copula function, which was selected from the commonly used copula classes by the empirical distribution based analysis method. The system time-variant fragility curves at different damage states were developed and the effects of time-varying dependences among components on the bridge system fragility were investigated. The results indicate the time-varying dependence among components significantly affects the time-variant fragility of the bridge system. The copula technique captures the nonlinear dependence among component seismic demands accurately and easily by separating the marginal distributions and the dependence among them. 展开更多
关键词 system FRAGILITY CHLORIDE corrosion TIME-VARYING dependence COPULA function probabilistic seismic demand
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基于改进的EfficientNet-B0网络的失能老人表情识别研究
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作者 李苏 何巍 《四川师范大学学报(自然科学版)》 2026年第1期97-105,共9页
为了能够更好地关注失能老人的情绪状态,针对传统模型在处理大规模参数、长时间训练以及捕获长距离依赖方面的问题,同时确保模型的轻量化以便于部署,提出一种改进的EfficientNet-B0模型用于表情识别.首先,利用迁移学习加速模型训练,以... 为了能够更好地关注失能老人的情绪状态,针对传统模型在处理大规模参数、长时间训练以及捕获长距离依赖方面的问题,同时确保模型的轻量化以便于部署,提出一种改进的EfficientNet-B0模型用于表情识别.首先,利用迁移学习加速模型训练,以减少对大规模数据的需求和加快训练速度;然后,对EfficientNet-B0结构进行了简化处理,可以降低模型的复杂度,提高运算效率;最后,引入非局部模块以增强全局特征关联性.实验结果显示,改进的EfficientNet-B0模型在RAF-DB和FER2013两个数据集上的识别率分别为88.40%和75.30%,这表明改进的方法在提高EfficientNet-B0模型性能方面取得了一定的成效. 展开更多
关键词 失能老人 表情识别 长距离依赖 迁移学习 非局部模块
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