Salinity is a major issue threatening global food security.Among the different strategies,nanotechnology has shown tremendous potential for improving crop production under abiotic stresses such as salinity.In this rev...Salinity is a major issue threatening global food security.Among the different strategies,nanotechnology has shown tremendous potential for improving crop production under abiotic stresses such as salinity.In this review,we discuss the environmental challenges associated with the different methods of nanomaterial application,including seed nanopriming,as well as foliar and soil/root application.Based on previous research,nanopriming uses less nanomaterials and has minimal concerns regarding environmental safety and the food chain.We discuss in detail the preventive measures for the safe and sustainable use of nanomaterials in agriculture based on the application methods.Furthermore,we summarize the role of antioxidant enzyme-triggering nanomaterials and direct reactive oxygen species(ROS)scavenging nanomaterials(nanozymes)in plant salt tolerance.Nanomaterials can improve sodium(Na^(+))and potassium(K^(+))homeostasis through various anatomical,physiological,and molecular mechanisms while improving plant salt tolerance.The role of nanomaterials in modulating plant photosynthesis and hormonal balance has been largely overlooked.We also identify research gaps and provide guidelines for future research work.This review provides guidelines for helping researchers to understand the proper design of nanoparticles(NPs)and different plant-related factors while using NPs for plant stress tolerance.These considerations will help to improve the efficient delivery of NPs into plants.Furthermore,after gaining sufficient scientific knowledge and better understanding,NPs can be integral to sustainable agriculture,while saving costs and reducing biosafety concerns and environmental pollution.展开更多
Aquick tap on your phone on your way to work has your usual co!ee arriving at the o"ce before you do.Preparing for an evening event,a new foundation shade arrives in under 30 minutes,no store visit required.At a ...Aquick tap on your phone on your way to work has your usual co!ee arriving at the o"ce before you do.Preparing for an evening event,a new foundation shade arrives in under 30 minutes,no store visit required.At a weekend picnic,pet treats show up from across town just as easily as lunch.Wake up at 2 a.m.with a sick child?Medicine is at your door within minutes.This is life with China’s rapidly developing sales model known as instant retail.Instant retail is an evolution of traditional food delivery,expanding the concept from meals to virtually anything consumers might need.By integrating online ordering with rapid local fulfillment,it connects digital platforms with brick-and-mortar stores and leverages efficient delivery networks to bring goods to consumers within 30 to 60 minutes.With its speed,flexibility,and broad range of offerings,instant retail is rapidly becoming an everyday feature of urban life and is transforming the future of The Economy in Real Time retail.展开更多
This study evaluated the water delivery performance of Nkhafi irrigation scheme based on adequacy, water delivery efficiency, equity, dependability and irrigation efficiency. Primary data were collected from </span...This study evaluated the water delivery performance of Nkhafi irrigation scheme based on adequacy, water delivery efficiency, equity, dependability and irrigation efficiency. Primary data were collected from </span><span style="font-family:""><span style="font-family:Verdana;">field measurements, scheduled interviews, group discussions and use of a structured questionnaire. CROPWAT 8.0 computer model was used to determine crop water requirements and irrigation requirements. </span><span style="font-family:Verdana;">The results revealed that adequacy, water delivery efficiency, equity, dependability and overall water delivery performance were (0.74;0.82), (0.70;0.80), (0.15;0.20), (0.11;0.21) and (0.80;0.80) for 2017 and 2018 seasons respectively. The scheme overall irrigation efficiencies were 20% and 25% for 2017 and 2018 respectively. These findings revealed that scheme users failed to deliver adequate and dependable water in an effective manner in both growing seasons. This occurred due to insufficient water supply, poor irrigation scheduling, lack of adequate knowledge and skills in operating and rehabilitating hydraulic structures, siltation and water losses through seepage in canals. Therefore, it is recommended that major maintenance works need to be done along the whole canal network in order to achieve good overall water delivery performance. Furthermore, farmers need to be trained in water management, sustainable agricultural production practices, operation and maintenance of irrigation structures. The study has provided an insight on the status of the scheme hence encouraging scheme users to improve water delivery performance.展开更多
Mobile Ad Hoc Networks consist of nodes which are wireless and get organized based on the transmission requirement. These nodes are mobile nodes, so they communicate with each other without any fixed access point. Thi...Mobile Ad Hoc Networks consist of nodes which are wireless and get organized based on the transmission requirement. These nodes are mobile nodes, so they communicate with each other without any fixed access point. This type of network faces several attacks because of its mobility nature. In MANET, black hole attacks may cause packet dropping or misrouting of packets during transmission from sender to receiver. This may lead to performance degradation in the network. To surmount this issue, we propose the modified secret sharing scheme to provide the data protection from unauthorized nodes, consistency of data and genuineness. In this algorithm, initially the identification of black hole attacks is achieved and followed by data protection from malicious nodes and also this scheme checks for the reality of the data. Here, we detect the misbehaviour that is dropping or misrouting using verifiable secret sharing scheme. The proposed algorithm achieves the better packet delivery ratio, misbehaviour detection efficiency, fewer packets overhead and end-to-end delay than the existing schemes. These can be viewed in the simulation results.展开更多
DNA nanostructures have emerged as promising carriers for drug delivery.However,challenges such as low stability,poor cellular uptake efficiency,and vulnerability to lysosomal degradation still hinder their therapeuti...DNA nanostructures have emerged as promising carriers for drug delivery.However,challenges such as low stability,poor cellular uptake efficiency,and vulnerability to lysosomal degradation still hinder their therapeutic potential.In this study,we demonstrate the coating of tetrahedral DNA frameworks(TDF)with the endosomolytic peptide L17E through electrostatic interactions to address these issues.Our findings highlight that L17E coating substantially enhances the stability of TDFs and improves their uptake efficiency into RAW264.7 cells through endocytosis and macropinocytosis.Moreover,L17E coating enables efficient endosomal release of TDFs.Finally,we employed L17E-coated TDF to deliver osteogenic growth peptide and demonstrated its potential applications in inhibiting periodontitis both in vitro and in vivo.This straightforward and cost-effective strategy holds promise for advancing the biomedical applications of DNA nanostructures.展开更多
Nano-enabled agriculture is a topic of intense research interest.However,our knowledge of how nanoparticles enter plants,plant cells,and organelles is still insufficient.Here,we discuss the barriers that limit the eff...Nano-enabled agriculture is a topic of intense research interest.However,our knowledge of how nanoparticles enter plants,plant cells,and organelles is still insufficient.Here,we discuss the barriers that limit the efficient delivery of nanoparticles at the whole-plant and single-cell levels.Some commonly overlooked factors,such as light conditions and surface tension of applied nano-formulations,are discussed.Knowledge gaps regarding plant cell uptake of nanoparticles,such as the effect of electrochemical gradients across organelle membranes on nanoparticle delivery,are analyzed and discussed.The importance of controlling factors such as size,charge,stability,and dispersibility when properly designing nanomaterials for plants is outlined.We mainly focus on understanding how nanoparticles travel across barriers in plants and plant cells and the major factors that limit the efficient delivery of nanoparticles,promoting a better understanding of nanoparticle–plant interactions.We also provide suggestions on the design of nanomaterials for nano-enabled agriculture.展开更多
基金supported by the Hainan Major Science and Technology Projects,China(ZDKJ202001)the Hainan Provincial Postdoctoral Research Projects awarded to Mohammad Nauman Khan,China(RZ2300005783)+1 种基金the Sao Paulo Research Foundation,Brazil(FAPESP,#2022/03219–2)the National Council for Scientific and Technological Development,Brazil(CNPQ,#310846/2022–6)。
文摘Salinity is a major issue threatening global food security.Among the different strategies,nanotechnology has shown tremendous potential for improving crop production under abiotic stresses such as salinity.In this review,we discuss the environmental challenges associated with the different methods of nanomaterial application,including seed nanopriming,as well as foliar and soil/root application.Based on previous research,nanopriming uses less nanomaterials and has minimal concerns regarding environmental safety and the food chain.We discuss in detail the preventive measures for the safe and sustainable use of nanomaterials in agriculture based on the application methods.Furthermore,we summarize the role of antioxidant enzyme-triggering nanomaterials and direct reactive oxygen species(ROS)scavenging nanomaterials(nanozymes)in plant salt tolerance.Nanomaterials can improve sodium(Na^(+))and potassium(K^(+))homeostasis through various anatomical,physiological,and molecular mechanisms while improving plant salt tolerance.The role of nanomaterials in modulating plant photosynthesis and hormonal balance has been largely overlooked.We also identify research gaps and provide guidelines for future research work.This review provides guidelines for helping researchers to understand the proper design of nanoparticles(NPs)and different plant-related factors while using NPs for plant stress tolerance.These considerations will help to improve the efficient delivery of NPs into plants.Furthermore,after gaining sufficient scientific knowledge and better understanding,NPs can be integral to sustainable agriculture,while saving costs and reducing biosafety concerns and environmental pollution.
文摘Aquick tap on your phone on your way to work has your usual co!ee arriving at the o"ce before you do.Preparing for an evening event,a new foundation shade arrives in under 30 minutes,no store visit required.At a weekend picnic,pet treats show up from across town just as easily as lunch.Wake up at 2 a.m.with a sick child?Medicine is at your door within minutes.This is life with China’s rapidly developing sales model known as instant retail.Instant retail is an evolution of traditional food delivery,expanding the concept from meals to virtually anything consumers might need.By integrating online ordering with rapid local fulfillment,it connects digital platforms with brick-and-mortar stores and leverages efficient delivery networks to bring goods to consumers within 30 to 60 minutes.With its speed,flexibility,and broad range of offerings,instant retail is rapidly becoming an everyday feature of urban life and is transforming the future of The Economy in Real Time retail.
文摘This study evaluated the water delivery performance of Nkhafi irrigation scheme based on adequacy, water delivery efficiency, equity, dependability and irrigation efficiency. Primary data were collected from </span><span style="font-family:""><span style="font-family:Verdana;">field measurements, scheduled interviews, group discussions and use of a structured questionnaire. CROPWAT 8.0 computer model was used to determine crop water requirements and irrigation requirements. </span><span style="font-family:Verdana;">The results revealed that adequacy, water delivery efficiency, equity, dependability and overall water delivery performance were (0.74;0.82), (0.70;0.80), (0.15;0.20), (0.11;0.21) and (0.80;0.80) for 2017 and 2018 seasons respectively. The scheme overall irrigation efficiencies were 20% and 25% for 2017 and 2018 respectively. These findings revealed that scheme users failed to deliver adequate and dependable water in an effective manner in both growing seasons. This occurred due to insufficient water supply, poor irrigation scheduling, lack of adequate knowledge and skills in operating and rehabilitating hydraulic structures, siltation and water losses through seepage in canals. Therefore, it is recommended that major maintenance works need to be done along the whole canal network in order to achieve good overall water delivery performance. Furthermore, farmers need to be trained in water management, sustainable agricultural production practices, operation and maintenance of irrigation structures. The study has provided an insight on the status of the scheme hence encouraging scheme users to improve water delivery performance.
文摘Mobile Ad Hoc Networks consist of nodes which are wireless and get organized based on the transmission requirement. These nodes are mobile nodes, so they communicate with each other without any fixed access point. This type of network faces several attacks because of its mobility nature. In MANET, black hole attacks may cause packet dropping or misrouting of packets during transmission from sender to receiver. This may lead to performance degradation in the network. To surmount this issue, we propose the modified secret sharing scheme to provide the data protection from unauthorized nodes, consistency of data and genuineness. In this algorithm, initially the identification of black hole attacks is achieved and followed by data protection from malicious nodes and also this scheme checks for the reality of the data. Here, we detect the misbehaviour that is dropping or misrouting using verifiable secret sharing scheme. The proposed algorithm achieves the better packet delivery ratio, misbehaviour detection efficiency, fewer packets overhead and end-to-end delay than the existing schemes. These can be viewed in the simulation results.
基金supported by the National Key R&D Program of China(2020YFA0908900)Universities Stable Funding Key Projects(WDZC20200821104802001)+2 种基金the State Key Laboratory of Chemical Oncogenomicsthe Institute of Biomedical Health Technology and Engineering of Shenzhen Bay LaboratoryGuangDong Basic and Applied Basic Research Foundation(2021A1515110819).
文摘DNA nanostructures have emerged as promising carriers for drug delivery.However,challenges such as low stability,poor cellular uptake efficiency,and vulnerability to lysosomal degradation still hinder their therapeutic potential.In this study,we demonstrate the coating of tetrahedral DNA frameworks(TDF)with the endosomolytic peptide L17E through electrostatic interactions to address these issues.Our findings highlight that L17E coating substantially enhances the stability of TDFs and improves their uptake efficiency into RAW264.7 cells through endocytosis and macropinocytosis.Moreover,L17E coating enables efficient endosomal release of TDFs.Finally,we employed L17E-coated TDF to deliver osteogenic growth peptide and demonstrated its potential applications in inhibiting periodontitis both in vitro and in vivo.This straightforward and cost-effective strategy holds promise for advancing the biomedical applications of DNA nanostructures.
基金supported by the NSFC(32071971 and 31901464)project 2662020ZKPY001 supported by the Fundamental Research Funds for the Central Universities,and joint project SZYJY2021008 from Huazhong Agricultural University and the Agricultural Genomics Institute at Shenzhen,Chinese Academy of Agricultural Sciences(to H.W.).
文摘Nano-enabled agriculture is a topic of intense research interest.However,our knowledge of how nanoparticles enter plants,plant cells,and organelles is still insufficient.Here,we discuss the barriers that limit the efficient delivery of nanoparticles at the whole-plant and single-cell levels.Some commonly overlooked factors,such as light conditions and surface tension of applied nano-formulations,are discussed.Knowledge gaps regarding plant cell uptake of nanoparticles,such as the effect of electrochemical gradients across organelle membranes on nanoparticle delivery,are analyzed and discussed.The importance of controlling factors such as size,charge,stability,and dispersibility when properly designing nanomaterials for plants is outlined.We mainly focus on understanding how nanoparticles travel across barriers in plants and plant cells and the major factors that limit the efficient delivery of nanoparticles,promoting a better understanding of nanoparticle–plant interactions.We also provide suggestions on the design of nanomaterials for nano-enabled agriculture.
