The paper demonstrates the possibility to enhance the damping of inter-area oscillations using Wide Area Measurement (WAM) based adaptive supervisory controller (ASC) which considers the wide-area signal transmission ...The paper demonstrates the possibility to enhance the damping of inter-area oscillations using Wide Area Measurement (WAM) based adaptive supervisory controller (ASC) which considers the wide-area signal transmission delays. The paper uses an LMI-based iterative nonlinear optimization algorithm to establish a method of designing state-feedback controllers for power systems with a time-varying delay. This method is based on the delay-dependent stabilization conditions obtained by the improved free weighting matrix (IFWM) approach. In the stabilization conditions, the upper bound of feedback signal’s transmission delays is taken into consideration. Combining theoriesof state feedback control and state observer, the ASC is designed and time-delay output feedback robust controller is realized for power system. The ASC uses the input information from Phase Measurement Units (PMUs) in the system and dispatches supplementary control signals to the available local controllers. The design of the ASC is explained in detail and its performance validated by time domain simulations on a New England test power system (NETPS).展开更多
In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to ...In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.展开更多
Driven by advancements in mobile internet technology,images have become a crucial data medium.Ensuring the security of image information during transmission has thus emerged as an urgent challenge.This study proposes ...Driven by advancements in mobile internet technology,images have become a crucial data medium.Ensuring the security of image information during transmission has thus emerged as an urgent challenge.This study proposes a novel image encryption algorithm specifically designed for grayscale image security.This research introduces a new Cantor diagonal matrix permutation method.The proposed permutation method uses row and column index sequences to control the Cantor diagonal matrix,where the row and column index sequences are generated by a spatiotemporal chaotic system named coupled map lattice(CML).The high initial value sensitivity of the CML system makes the permutation method highly sensitive and secure.Additionally,leveraging fractal theory,this study introduces a chaotic fractal matrix and applies this matrix in the diffusion process.This chaotic fractal matrix exhibits selfsimilarity and irregularity.Using the Cantor diagonal matrix and chaotic fractal matrix,this paper introduces a fast image encryption algorithm involving two diffusion steps and one permutation step.Moreover,the algorithm achieves robust security with only a single encryption round,ensuring high operational efficiency.Experimental results show that the proposed algorithm features an expansive key space,robust security,high sensitivity,high efficiency,and superior statistical properties for the ciphered images.Thus,the proposed algorithm not only provides a practical solution for secure image transmission but also bridges fractal theory with image encryption techniques,thereby opening new research avenues in chaotic cryptography and advancing the development of information security technology.展开更多
We read with the great interest the study by Ababneh et al in which inducedmesenchymal stem cell-derived exosomes were shown to exhibit a stronger andmore sustained anti-proliferative effect by inducing a senescence-l...We read with the great interest the study by Ababneh et al in which inducedmesenchymal stem cell-derived exosomes were shown to exhibit a stronger andmore sustained anti-proliferative effect by inducing a senescence-like state withoutapoptosis.The results obtained by the authors highlight the features of theeffects of senescent drift induction in surrounding tissues.In the light of thesefindings,the role of the properties of extracellular matrix and cellular glycocalyxin responses of human tumors to therapy remain uninvestigated.These extracellularbarriers appear to be significant obstacles to effective cancer therapy,especiallyin relation to the use of unique properties of tumor microenvironment forthe immunotherapy-resistant cancer treatment.展开更多
Peripheral nerve injury causes severe neuroinflammation and has become a global medical challenge.Previous research has demonstrated that porcine decellularized nerve matrix hydrogel exhibits excellent biological prop...Peripheral nerve injury causes severe neuroinflammation and has become a global medical challenge.Previous research has demonstrated that porcine decellularized nerve matrix hydrogel exhibits excellent biological properties and tissue specificity,highlighting its potential as a biomedical material for the repair of severe peripheral nerve injury;however,its role in modulating neuroinflammation post-peripheral nerve injury remains unknown.Here,we aimed to characterize the anti-inflammatory properties of porcine decellularized nerve matrix hydrogel and their underlying molecular mechanisms.Using peripheral nerve injury model rats treated with porcine decellularized nerve matrix hydrogel,we evaluated structural and functional recovery,macrophage phenotype alteration,specific cytokine expression,and changes in related signaling molecules in vivo.Similar parameters were evaluated in vitro using monocyte/macrophage cell lines stimulated with lipopolysaccharide and cultured on porcine decellularized nerve matrix hydrogel-coated plates in complete medium.These comprehensive analyses revealed that porcine decellularized nerve matrix hydrogel attenuated the activation of excessive inflammation at the early stage of peripheral nerve injury and increased the proportion of the M2 subtype in monocytes/macrophages.Additionally,porcine decellularized nerve matrix hydrogel negatively regulated the Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB axis both in vivo and in vitro.Our findings suggest that the efficacious anti-inflammatory properties of porcine decellularized nerve matrix hydrogel induce M2 macrophage polarization via suppression of the Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB pathway,providing new insights into the therapeutic mechanism of porcine decellularized nerve matrix hydrogel in peripheral nerve injury.展开更多
Objectives:High-grade serous ovarian cancer(HGSOC),the most common subtype of epithelial ovarian cancer(EOC),exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis.Human epididymis protei...Objectives:High-grade serous ovarian cancer(HGSOC),the most common subtype of epithelial ovarian cancer(EOC),exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis.Human epididymis protein 4(HE4),a key diagnostic biomarker for ovarian cancer,is involved in fibrotic processes in several non-malignant diseases.Given the clinical significance of stromal fibrosis in HGSOC and the potential link between HE4 and fibrosis,this study aimed to investigate the role of HE4 in the formation of stromal fibrosis in HGSOC.Methods:A total of 126 patients with gynecological conditions were included and divided into normal,benign,and EOC groups.Tissue stiffness was quantitatively measured and analyzed for its correlation with clinicopathological features.We further investigated the correlation between tumor stiffness and the expression levels of HE4 and fibroblast activation markers(α-smooth muscle actin(α-SMA)and fibroblast activation protein(FAP))in tumor tissues from 22 HGSOC patients.In vitro,primary fibroblasts were treated with recombinant HE4(rHE4)or conditioned media from HE4-knockdown ovarian cancer cells to assess fibroblasts activation and matrix contractility(Collagen gel contraction assays).In vivo,a subcutaneous xenograft model using HE4-knockdown cells was established to evaluate the effects of HE4 suppression on tumor growth and extensive extracellular matrix(ECM)remodeling.Results:Ovarian cancer tissues showed significantly increased stiffness compared to benign/normal groups,showing positive correlation with serum HE4 levels.High-stiffness HGSOC tumors exhibited upregulated expression of HE4,α-SMA,FAP,and collagen I.rHE4 stimulated fibroblast activation and enhanced matrix contractility,whereas HE4 knockdown in cancer cells abrogated these pro-fibrotic effects.In vivo,HE4-silenced xenografts displayed restricted tumor growth accompanied by reduced stromal expression ofα-SMA,FAP,and collagen I.Conclusion:Our findings suggest that HE4 may facilitate ECM remodeling in HGSOC through promoting fibroblast activation and increasing collagen deposition.展开更多
The delay-dependent absolute stability for a class of Lurie systems with interval time-varying delay is studied. By employing an augmented Lyapunov functional and combining a free-weighting matrix approach and the rec...The delay-dependent absolute stability for a class of Lurie systems with interval time-varying delay is studied. By employing an augmented Lyapunov functional and combining a free-weighting matrix approach and the reciprocal convex technique, an improved stability condition is derived in terms of linear matrix inequalities （LMIs）. By retaining some useful terms that are usually ignored in the derivative of the Lyapunov function, the proposed sufficient condition depends not only on the lower and upper bounds of both the delay and its derivative, but it also depends on their differences, which has wider application fields than those of present results. Moreover, a new type of equality expression is developed to handle the sector bounds of the nonlinear function, which achieves fewer LMIs in the derived condition, compared with those based on the convex representation. Therefore, the proposed method is less conservative than the existing ones. Simulation examples are given to demonstrate the validity of the approach.展开更多
The problem of the stability for a class of stochastic systems with time-varying interval delay and the norm-bounded uncertainty is investigated. Utilizing the information of both the lower and the upper bounds of the...The problem of the stability for a class of stochastic systems with time-varying interval delay and the norm-bounded uncertainty is investigated. Utilizing the information of both the lower and the upper bounds of the interval time-varying delay, a novel Lyapunov-Krasovskii functional is constructed. The delay-dependent sufficient criteria are derived in terms of linear matrix inequalities （LMIs）, which can be easily checked by the LMI in the Matlab toolbox. Based on the Jensen integral inequality, neither model transformations nor bounding techniques for cross terms is employed, so the derived criteria are less conservative than the existing results. Meanwhile, the computational complexity of the obtained stability conditions is reduced because no redundant matrix is introduced. A numerical example is given to show the effectiveness and the benefits of the proposed method.展开更多
The problem of delay-dependent criteria for the robust stability of neutral systems with time-varying structured uncertainties and identi-cal neutral-delay and discrete-delay is concerned. A criterion for nominal syst...The problem of delay-dependent criteria for the robust stability of neutral systems with time-varying structured uncertainties and identi-cal neutral-delay and discrete-delay is concerned. A criterion for nominal systems is presented by taking the relationship between the terms in the Leibniz-Newton formula into account, which is described by some free-weighting matrices. In addition, this criterion is extended to robust stability of the systems with time-varying structured uncertainties. All of the criteria are based on linear matrix inequality such that it is easy to calculate the upper bound of the time-delay and the free-weighting matrices. Numerical examples illustrate the effectiveness and the improvement over the existing results.展开更多
This paper investigates the problem of delay-dependent robust stabilization for uncertain singular systems with discrete and distributed delays in terms of linear matrix inequality （LMI） approach. Based on a delay-d...This paper investigates the problem of delay-dependent robust stabilization for uncertain singular systems with discrete and distributed delays in terms of linear matrix inequality （LMI） approach. Based on a delay-dependent stability condition for the nominal system, a state feedback controller is designed, which guarantees the resultant closed- loop system to be robustly stable. An explicit expression for the desired controller is also given by solving a set of matrix inequalities. Some numerical examples are provided to illustrate the less conservativeness of the proposed methods.展开更多
The delay-dependent robust stability of uncertain linear neutral systems with delays is investigated. Both discrete-delay-dependent/neutral-delay-independent and neutral-/discrete- delay-dependent stability criteria w...The delay-dependent robust stability of uncertain linear neutral systems with delays is investigated. Both discrete-delay-dependent/neutral-delay-independent and neutral-/discrete- delay-dependent stability criteria will be developed. The proposed stability criteria are formulated in the form of linear matrix inequalities and it is easy to check the robust stability of the considered systems. By introducing certain Lyapunov-Krasovskii functional the mathematical development of our result avoids model transformation and bounding for cross terms, which lead to conservatism. Finally, numerical example is given to indicate the improvement over some existing results.展开更多
This paper considers the guaranteed cost control problem for a class of uncertain linear systems with both state and input delays. By representing the time-delay system in the descriptor system form and using a recent...This paper considers the guaranteed cost control problem for a class of uncertain linear systems with both state and input delays. By representing the time-delay system in the descriptor system form and using a recent result on bounding of cross products of vectors, we obtain new delay-dependent sufficient conditions for the existence of the guaranteed cost controller in terms of linear matrix inequalities. Two examples are presented which show the effectiveness of our approach.展开更多
The problem of delay-dependent robust stability for systems with time-varying delay has been considered. By using the S-procedure and the Park's inequality in the recent issue, a delay-dependent robust stability c...The problem of delay-dependent robust stability for systems with time-varying delay has been considered. By using the S-procedure and the Park's inequality in the recent issue, a delay-dependent robust stability criterion which is less conservative than the previous results has been derived for time-delay systems with time-varying structured uncertainties. The same idea has also been easily extended to the systems with nonlinear perturbations. Numerical examples illustrated the effectiveness and the improvement of the proposed approach. Keywords Delay-dependent criteria - Robust stability - Time-varying structured uncertainties - Nonlinear perturbations - Linear matrix inequality This work was supported by the Doctor Subject Foundation of China (No. 2000053303).展开更多
This paper deals with the problem of delay-dependent robust stability for a class of switched Hopfield neural networks with time-varying structured uncertainties and time-varying delay. Some Lyapunov-KrasoVskii functi...This paper deals with the problem of delay-dependent robust stability for a class of switched Hopfield neural networks with time-varying structured uncertainties and time-varying delay. Some Lyapunov-KrasoVskii functionals are constructed and the linear matrix inequality （LMI） approach and free weighting matrix method are employed to devise some delay-dependent stability criteria which guarantee the existence, uniqueness and global exponential stability of the equilibrium point for all admissible parametric uncertainties. By using Leibniz-Newton formula, free weighting matrices are employed to express this relationship, which implies that the new criteria are less conservative than existing ones. Some examples suggest that the proposed criteria are effective and are an improvement over previous ones.展开更多
It is well-recognized that a transfer system response delay that reduces the test stability inevitably exists in real-time dynamic hybrid testing （RTDHT）. This paper focuses on the delay-dependent stability and adde...It is well-recognized that a transfer system response delay that reduces the test stability inevitably exists in real-time dynamic hybrid testing （RTDHT）. This paper focuses on the delay-dependent stability and added damping of SDOF systems in RTDHT. The exponential delay term is transferred into a rational fraction by the Pad6 approximation, and the delay-dependent stability conditions and instability mechanism of SDOF RTDHT systems are investigated by the root locus technique. First, the stability conditions are discussed separately for the cases of stiffness, mass, and damping experimental substructure. The use of root locus plots shows that the added damping effect and instability mechanism for mass are different from those for stiffness. For the stiffness experimental substructure case, the instability results from the inherent mode because of an obvious negative damping effect of the delay. For the mass case, the delay introduces an equivalent positive damping into the inherent mode, and instability occurs at an added high frequency mode. Then, the compound stability condition is investigated for a general case and the results show that the mass ratio may have both upper and lower limits to remain stable. Finally, a high-emulational virtual shaking table model is built to validate the stability conclusions.展开更多
In this paper, delay-dependent stability analysis and robust stabilization for uncertain singular time-delay systems are addressed. By using Jensen integral inequality, an improved delay-dependent criterion of admissi...In this paper, delay-dependent stability analysis and robust stabilization for uncertain singular time-delay systems are addressed. By using Jensen integral inequality, an improved delay-dependent criterion of admissibility for singular time-delay systems is proposed in terms of linear matrix inequality （LMI）. Our new proposed criterion is less conservative and the numerical complexity is smaller than the existing ones. Based on this criterion, a state feedback controller is designed to ensure that the uncertain singular time-delay system is admissible. Finally, three numerical examples are employed to illustrate the effectiveness of the proposed method.展开更多
This paper deals with the delay-dependent stabilization problem for singular systems with Markovian jump parameters and time delays.A delay-dependent condition is established for the considered system to be regular,im...This paper deals with the delay-dependent stabilization problem for singular systems with Markovian jump parameters and time delays.A delay-dependent condition is established for the considered system to be regular,impulse free and stochastically stable.Based on the condition,a design algorithm of the desired state feedback controller which guarantees the resultant closed-loop system to be regular,impulse free and stochastically stable is proposed in terms of a set of strict linear matrix inequalities(LMIs).Numerical examples show the effectiveness of the proposed methods.展开更多
The problem of delay-dependent stability and passivity for linear neutral systems is discussed.By constructing a novel type Lyapunov-krasovskii functional,a new delay-dependent passivity criterion is presented in term...The problem of delay-dependent stability and passivity for linear neutral systems is discussed.By constructing a novel type Lyapunov-krasovskii functional,a new delay-dependent passivity criterion is presented in terms of linear matrix inequalities(LMIs).Model transformation,bounding for cross terms and selecting free weighting matrices[12-14]are not required in the arguments.Numerical examples show that the proposed criteria are available and less conservative than existing results.展开更多
文摘The paper demonstrates the possibility to enhance the damping of inter-area oscillations using Wide Area Measurement (WAM) based adaptive supervisory controller (ASC) which considers the wide-area signal transmission delays. The paper uses an LMI-based iterative nonlinear optimization algorithm to establish a method of designing state-feedback controllers for power systems with a time-varying delay. This method is based on the delay-dependent stabilization conditions obtained by the improved free weighting matrix (IFWM) approach. In the stabilization conditions, the upper bound of feedback signal’s transmission delays is taken into consideration. Combining theoriesof state feedback control and state observer, the ASC is designed and time-delay output feedback robust controller is realized for power system. The ASC uses the input information from Phase Measurement Units (PMUs) in the system and dispatches supplementary control signals to the available local controllers. The design of the ASC is explained in detail and its performance validated by time domain simulations on a New England test power system (NETPS).
基金Supported in part by Natural Science Foundation of Guangxi(2023GXNSFAA026246)in part by the Central Government's Guide to Local Science and Technology Development Fund(GuikeZY23055044)in part by the National Natural Science Foundation of China(62363003)。
文摘In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.
基金supported by the National Natural Science Foundation of China(62376106)The Science and Technology Development Plan of Jilin Province(20250102212JC).
文摘Driven by advancements in mobile internet technology,images have become a crucial data medium.Ensuring the security of image information during transmission has thus emerged as an urgent challenge.This study proposes a novel image encryption algorithm specifically designed for grayscale image security.This research introduces a new Cantor diagonal matrix permutation method.The proposed permutation method uses row and column index sequences to control the Cantor diagonal matrix,where the row and column index sequences are generated by a spatiotemporal chaotic system named coupled map lattice(CML).The high initial value sensitivity of the CML system makes the permutation method highly sensitive and secure.Additionally,leveraging fractal theory,this study introduces a chaotic fractal matrix and applies this matrix in the diffusion process.This chaotic fractal matrix exhibits selfsimilarity and irregularity.Using the Cantor diagonal matrix and chaotic fractal matrix,this paper introduces a fast image encryption algorithm involving two diffusion steps and one permutation step.Moreover,the algorithm achieves robust security with only a single encryption round,ensuring high operational efficiency.Experimental results show that the proposed algorithm features an expansive key space,robust security,high sensitivity,high efficiency,and superior statistical properties for the ciphered images.Thus,the proposed algorithm not only provides a practical solution for secure image transmission but also bridges fractal theory with image encryption techniques,thereby opening new research avenues in chaotic cryptography and advancing the development of information security technology.
文摘We read with the great interest the study by Ababneh et al in which inducedmesenchymal stem cell-derived exosomes were shown to exhibit a stronger andmore sustained anti-proliferative effect by inducing a senescence-like state withoutapoptosis.The results obtained by the authors highlight the features of theeffects of senescent drift induction in surrounding tissues.In the light of thesefindings,the role of the properties of extracellular matrix and cellular glycocalyxin responses of human tumors to therapy remain uninvestigated.These extracellularbarriers appear to be significant obstacles to effective cancer therapy,especiallyin relation to the use of unique properties of tumor microenvironment forthe immunotherapy-resistant cancer treatment.
基金supported by the Shenzhen Hong Kong Joint Funding Project,No.SGDX20230116093645007(to LY)the Shenzhen Science and Technology Innovation Committee International Cooperation Project,No.GJHZ20200731095608025(to LY)+7 种基金Shenzhen Development and Reform Commission’s Intelligent Diagnosis,Treatment and Prevention of Adolescent Spinal Health Public Service Platform,No.S2002Q84500835(to LY)Shenzhen Medical Research Fund,No.B2303005(to LY)Team-based Medical Science Research Program,No.2024YZZ02(to LY)Zhejiang Provincial Natural Science Foundation of China,No.LWQ20H170001(to RL)Basic Research Project of Shenzhen Science and Technology from Shenzhen Science and Technology Innovation Commission,No.JCYJ20210324103010029(to BY)Shenzhen Second People’s Hospital Clinical Research Fund of Guangdong Province High-level Hospital Construction Project,Nos.2023yjlcyj029(to BY),2023yjlcyj021(to LL)Guangdong Basic and Applied Basic Research Foundation,No.2022A1515110679(to LL)China Postdoctoral Science Foundation,No.2022M722203(to GL).
文摘Peripheral nerve injury causes severe neuroinflammation and has become a global medical challenge.Previous research has demonstrated that porcine decellularized nerve matrix hydrogel exhibits excellent biological properties and tissue specificity,highlighting its potential as a biomedical material for the repair of severe peripheral nerve injury;however,its role in modulating neuroinflammation post-peripheral nerve injury remains unknown.Here,we aimed to characterize the anti-inflammatory properties of porcine decellularized nerve matrix hydrogel and their underlying molecular mechanisms.Using peripheral nerve injury model rats treated with porcine decellularized nerve matrix hydrogel,we evaluated structural and functional recovery,macrophage phenotype alteration,specific cytokine expression,and changes in related signaling molecules in vivo.Similar parameters were evaluated in vitro using monocyte/macrophage cell lines stimulated with lipopolysaccharide and cultured on porcine decellularized nerve matrix hydrogel-coated plates in complete medium.These comprehensive analyses revealed that porcine decellularized nerve matrix hydrogel attenuated the activation of excessive inflammation at the early stage of peripheral nerve injury and increased the proportion of the M2 subtype in monocytes/macrophages.Additionally,porcine decellularized nerve matrix hydrogel negatively regulated the Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB axis both in vivo and in vitro.Our findings suggest that the efficacious anti-inflammatory properties of porcine decellularized nerve matrix hydrogel induce M2 macrophage polarization via suppression of the Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB pathway,providing new insights into the therapeutic mechanism of porcine decellularized nerve matrix hydrogel in peripheral nerve injury.
文摘Objectives:High-grade serous ovarian cancer(HGSOC),the most common subtype of epithelial ovarian cancer(EOC),exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis.Human epididymis protein 4(HE4),a key diagnostic biomarker for ovarian cancer,is involved in fibrotic processes in several non-malignant diseases.Given the clinical significance of stromal fibrosis in HGSOC and the potential link between HE4 and fibrosis,this study aimed to investigate the role of HE4 in the formation of stromal fibrosis in HGSOC.Methods:A total of 126 patients with gynecological conditions were included and divided into normal,benign,and EOC groups.Tissue stiffness was quantitatively measured and analyzed for its correlation with clinicopathological features.We further investigated the correlation between tumor stiffness and the expression levels of HE4 and fibroblast activation markers(α-smooth muscle actin(α-SMA)and fibroblast activation protein(FAP))in tumor tissues from 22 HGSOC patients.In vitro,primary fibroblasts were treated with recombinant HE4(rHE4)or conditioned media from HE4-knockdown ovarian cancer cells to assess fibroblasts activation and matrix contractility(Collagen gel contraction assays).In vivo,a subcutaneous xenograft model using HE4-knockdown cells was established to evaluate the effects of HE4 suppression on tumor growth and extensive extracellular matrix(ECM)remodeling.Results:Ovarian cancer tissues showed significantly increased stiffness compared to benign/normal groups,showing positive correlation with serum HE4 levels.High-stiffness HGSOC tumors exhibited upregulated expression of HE4,α-SMA,FAP,and collagen I.rHE4 stimulated fibroblast activation and enhanced matrix contractility,whereas HE4 knockdown in cancer cells abrogated these pro-fibrotic effects.In vivo,HE4-silenced xenografts displayed restricted tumor growth accompanied by reduced stromal expression ofα-SMA,FAP,and collagen I.Conclusion:Our findings suggest that HE4 may facilitate ECM remodeling in HGSOC through promoting fibroblast activation and increasing collagen deposition.
基金The National Natural Science Foundation of China(No.60835001,60875035,60905009,61004032,61004064,11071001)China Postdoctoral Science Foundation(No.201003546)+2 种基金the Ph.D.Programs Foundation of Ministry of Education of China(No.20093401110001)the Major Program of Higher Education of Anhui Province(No.KJ2010ZD02)the Natural Science Research Project of Higher Education of Anhui Province(No.KJ2011A020)
文摘The delay-dependent absolute stability for a class of Lurie systems with interval time-varying delay is studied. By employing an augmented Lyapunov functional and combining a free-weighting matrix approach and the reciprocal convex technique, an improved stability condition is derived in terms of linear matrix inequalities （LMIs）. By retaining some useful terms that are usually ignored in the derivative of the Lyapunov function, the proposed sufficient condition depends not only on the lower and upper bounds of both the delay and its derivative, but it also depends on their differences, which has wider application fields than those of present results. Moreover, a new type of equality expression is developed to handle the sector bounds of the nonlinear function, which achieves fewer LMIs in the derived condition, compared with those based on the convex representation. Therefore, the proposed method is less conservative than the existing ones. Simulation examples are given to demonstrate the validity of the approach.
基金The National Natural Science Foundation of China(No.60874030,60574006,60404006)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(No.07KJB510125)
文摘The problem of the stability for a class of stochastic systems with time-varying interval delay and the norm-bounded uncertainty is investigated. Utilizing the information of both the lower and the upper bounds of the interval time-varying delay, a novel Lyapunov-Krasovskii functional is constructed. The delay-dependent sufficient criteria are derived in terms of linear matrix inequalities （LMIs）, which can be easily checked by the LMI in the Matlab toolbox. Based on the Jensen integral inequality, neither model transformations nor bounding techniques for cross terms is employed, so the derived criteria are less conservative than the existing results. Meanwhile, the computational complexity of the obtained stability conditions is reduced because no redundant matrix is introduced. A numerical example is given to show the effectiveness and the benefits of the proposed method.
文摘The problem of delay-dependent criteria for the robust stability of neutral systems with time-varying structured uncertainties and identi-cal neutral-delay and discrete-delay is concerned. A criterion for nominal systems is presented by taking the relationship between the terms in the Leibniz-Newton formula into account, which is described by some free-weighting matrices. In addition, this criterion is extended to robust stability of the systems with time-varying structured uncertainties. All of the criteria are based on linear matrix inequality such that it is easy to calculate the upper bound of the time-delay and the free-weighting matrices. Numerical examples illustrate the effectiveness and the improvement over the existing results.
基金the National Natural Science Foundation of China (No.60503027)
文摘This paper investigates the problem of delay-dependent robust stabilization for uncertain singular systems with discrete and distributed delays in terms of linear matrix inequality （LMI） approach. Based on a delay-dependent stability condition for the nominal system, a state feedback controller is designed, which guarantees the resultant closed- loop system to be robustly stable. An explicit expression for the desired controller is also given by solving a set of matrix inequalities. Some numerical examples are provided to illustrate the less conservativeness of the proposed methods.
基金This work was supported by the National Natural Science Foundation of China(No. 60473120).
文摘The delay-dependent robust stability of uncertain linear neutral systems with delays is investigated. Both discrete-delay-dependent/neutral-delay-independent and neutral-/discrete- delay-dependent stability criteria will be developed. The proposed stability criteria are formulated in the form of linear matrix inequalities and it is easy to check the robust stability of the considered systems. By introducing certain Lyapunov-Krasovskii functional the mathematical development of our result avoids model transformation and bounding for cross terms, which lead to conservatism. Finally, numerical example is given to indicate the improvement over some existing results.
基金This work was supported by the National Natural Science Foundation of China (No. 10461001).
文摘This paper considers the guaranteed cost control problem for a class of uncertain linear systems with both state and input delays. By representing the time-delay system in the descriptor system form and using a recent result on bounding of cross products of vectors, we obtain new delay-dependent sufficient conditions for the existence of the guaranteed cost controller in terms of linear matrix inequalities. Two examples are presented which show the effectiveness of our approach.
文摘The problem of delay-dependent robust stability for systems with time-varying delay has been considered. By using the S-procedure and the Park's inequality in the recent issue, a delay-dependent robust stability criterion which is less conservative than the previous results has been derived for time-delay systems with time-varying structured uncertainties. The same idea has also been easily extended to the systems with nonlinear perturbations. Numerical examples illustrated the effectiveness and the improvement of the proposed approach. Keywords Delay-dependent criteria - Robust stability - Time-varying structured uncertainties - Nonlinear perturbations - Linear matrix inequality This work was supported by the Doctor Subject Foundation of China (No. 2000053303).
基金This work is supported by the National Natural Science Foundation of China (No.60674026)the Key Research Foundation of Science and Technology of the Ministry of Education of China (No.107058).
文摘This paper deals with the problem of delay-dependent robust stability for a class of switched Hopfield neural networks with time-varying structured uncertainties and time-varying delay. Some Lyapunov-KrasoVskii functionals are constructed and the linear matrix inequality （LMI） approach and free weighting matrix method are employed to devise some delay-dependent stability criteria which guarantee the existence, uniqueness and global exponential stability of the equilibrium point for all admissible parametric uncertainties. By using Leibniz-Newton formula, free weighting matrices are employed to express this relationship, which implies that the new criteria are less conservative than existing ones. Some examples suggest that the proposed criteria are effective and are an improvement over previous ones.
基金State Key Laboratory of Hydroscience and Engineering Under Grant No.2008-TC-2National Natural Science Foundation of China Under Grant No.90510018,50779021 and 90715041
文摘It is well-recognized that a transfer system response delay that reduces the test stability inevitably exists in real-time dynamic hybrid testing （RTDHT）. This paper focuses on the delay-dependent stability and added damping of SDOF systems in RTDHT. The exponential delay term is transferred into a rational fraction by the Pad6 approximation, and the delay-dependent stability conditions and instability mechanism of SDOF RTDHT systems are investigated by the root locus technique. First, the stability conditions are discussed separately for the cases of stiffness, mass, and damping experimental substructure. The use of root locus plots shows that the added damping effect and instability mechanism for mass are different from those for stiffness. For the stiffness experimental substructure case, the instability results from the inherent mode because of an obvious negative damping effect of the delay. For the mass case, the delay introduces an equivalent positive damping into the inherent mode, and instability occurs at an added high frequency mode. Then, the compound stability condition is investigated for a general case and the results show that the mass ratio may have both upper and lower limits to remain stable. Finally, a high-emulational virtual shaking table model is built to validate the stability conclusions.
基金supported by National Natural Science Foundation of China (No.60904009,No.60974004)
文摘In this paper, delay-dependent stability analysis and robust stabilization for uncertain singular time-delay systems are addressed. By using Jensen integral inequality, an improved delay-dependent criterion of admissibility for singular time-delay systems is proposed in terms of linear matrix inequality （LMI）. Our new proposed criterion is less conservative and the numerical complexity is smaller than the existing ones. Based on this criterion, a state feedback controller is designed to ensure that the uncertain singular time-delay system is admissible. Finally, three numerical examples are employed to illustrate the effectiveness of the proposed method.
基金supported by the National Creative Research Groups Science Foundation of China(No.60721062)the National High Technology Research and Development Program of China(863 Program)(2006AA04 Z182)the National Natural Science Foundation of China(No.60736021)
文摘This paper deals with the delay-dependent stabilization problem for singular systems with Markovian jump parameters and time delays.A delay-dependent condition is established for the considered system to be regular,impulse free and stochastically stable.Based on the condition,a design algorithm of the desired state feedback controller which guarantees the resultant closed-loop system to be regular,impulse free and stochastically stable is proposed in terms of a set of strict linear matrix inequalities(LMIs).Numerical examples show the effectiveness of the proposed methods.
基金This work was supported by the National Natural Science Foundation of China(No.60474003).
文摘The problem of delay-dependent stability and passivity for linear neutral systems is discussed.By constructing a novel type Lyapunov-krasovskii functional,a new delay-dependent passivity criterion is presented in terms of linear matrix inequalities(LMIs).Model transformation,bounding for cross terms and selecting free weighting matrices[12-14]are not required in the arguments.Numerical examples show that the proposed criteria are available and less conservative than existing results.
