Tissue expansion is a frequently used intervention for the reconstruction of large defects.Flap necrosis is one of the most troublesome complications,which may result in postoperative infection,an additional surgical ...Tissue expansion is a frequently used intervention for the reconstruction of large defects.Flap necrosis is one of the most troublesome complications,which may result in postoperative infection,an additional surgical procedure and unsatisfactory aesthetic and functional outcomes in the recipient sites.Therefore,to ensure sufficient perfusion of the expanded flaps,it is necessary to assess the flap perfusion intraoperatively[1].Traditionally,the assessment of flap perfusion is primarily based on subjective clinical observations of flap color,capillary refill,and pinprick bleeding,which can be misleading.ICGA is a real-time vascular fluorescent imaging technique that uses indocyanine green(ICG)as a contrast agent and near-infrared laser as excitation light.Previous research on the use of ICGA to predict flap necrosis has suggested the predictive fluorescence cutoff values for non-expanded flaps.As for expanded flaps,no cutoff value to predict postoperative necrosis has been identified to date.Consequently,the purpose of this study was to evaluate the predictive value of ICGA on expanded flap viability and to determine the optimal fluorescent cutoff value for intraoperative decision making to prevent postoperative necrosis[2].展开更多
基金supported by the National Natural Science Foundation of China(82072177,82272264)‘Two Hundred Talent’program and‘Hengjie’Program of Shanghai Health Youth Talent Reward Foundation.
文摘Tissue expansion is a frequently used intervention for the reconstruction of large defects.Flap necrosis is one of the most troublesome complications,which may result in postoperative infection,an additional surgical procedure and unsatisfactory aesthetic and functional outcomes in the recipient sites.Therefore,to ensure sufficient perfusion of the expanded flaps,it is necessary to assess the flap perfusion intraoperatively[1].Traditionally,the assessment of flap perfusion is primarily based on subjective clinical observations of flap color,capillary refill,and pinprick bleeding,which can be misleading.ICGA is a real-time vascular fluorescent imaging technique that uses indocyanine green(ICG)as a contrast agent and near-infrared laser as excitation light.Previous research on the use of ICGA to predict flap necrosis has suggested the predictive fluorescence cutoff values for non-expanded flaps.As for expanded flaps,no cutoff value to predict postoperative necrosis has been identified to date.Consequently,the purpose of this study was to evaluate the predictive value of ICGA on expanded flap viability and to determine the optimal fluorescent cutoff value for intraoperative decision making to prevent postoperative necrosis[2].
