Although machine Learning has demonstrated exceptional applicability in thermographic inspection,precise defect reconstruction is still challenging,especially for complex defect profiles with limited defect sample div...Although machine Learning has demonstrated exceptional applicability in thermographic inspection,precise defect reconstruction is still challenging,especially for complex defect profiles with limited defect sample diversity.Thus,this paper proposes a self-enhancement defect reconstruction technique based on cycle-consistent generative adversarial network(Cycle-GAN)that accurately characterises complex defect profiles and generates reliable artificial thermal images for dataset augmentation,enhancing defect characterisation.By using a synthetic dataset from simulation and experiments,the network overcomes the limited samples problem by learning the diversity of complex defects from finite element modelling and obtaining the thermography uncertainty patterns from practical experiments.Then,an iterative strategy with a self-enhancement capability optimises the characterisation accuracy and data generation performance.The designed loss function structure with cycle consistency and identity loss constrains the GAN’s transfer variation to guarantee augmented data quality and defect reconstruction accuracy simultaneously,while the self-enhancement results significantly improve accuracy in thermal images and defect profile reconstruction.The experimental results demonstrate the feasibility of the proposed method by attaining high accuracy with optimal loss norm for defect profile reconstruction with a Recall score over 0.92.The scalability investigation of different materials and defect types is also discussed,highlighting its capability for diverse thermography quantification and automated inspection scenarios.展开更多
BACKGROUND Total pharyngo-laryngo-esophagectomy with a reconstruction of gastric pull-up is the most common treatment method for patients with multiple primary upper digestive tract carcinomas,such as hypopharyngeal c...BACKGROUND Total pharyngo-laryngo-esophagectomy with a reconstruction of gastric pull-up is the most common treatment method for patients with multiple primary upper digestive tract carcinomas,such as hypopharyngeal carcinoma with thoracic esophageal carcinoma.However,neck circumferential defect and tracheoesophageal fistula after gastric necrosis are still challenging problems for surgeons and patients.CASE SUMMARY This case report presents 2 patients who underwent reconstructive surgeries using 4 local random flaps with a split thickness skin graft in the first case,and 6 local random flaps in the second case to close the circumferential defect and tracheoesophageal fistula after failed gastric pull-up.Both patients achieved good swallowing function and could take solid diet without dysphagia postoperatively.CONCLUSION For selected patients,local random flaps(with a split thickness skin graft)can be a simple and reliable solution for reconstructing tracheoesophageal fistula or cervical circumferential defect after gastric necrosis,especially when the necrosis extends below the thoracic inlet.展开更多
To the editor In 2003,Schwabegger et al.proposed the muscle-sparing latissimus dorsi(MS-LD)flap[1],which preserved a portion of the latissimus dorsi(LD)muscle around the point where the thoracodorsal artery(TDA)perfor...To the editor In 2003,Schwabegger et al.proposed the muscle-sparing latissimus dorsi(MS-LD)flap[1],which preserved a portion of the latissimus dorsi(LD)muscle around the point where the thoracodorsal artery(TDA)perforator penetrates the muscle,having the advantages of a sufficient flap blood supply and reduced donor-site morbidity.However,the traditional MS-LD flap is still too bulky for the reconstruction of defects of the face and neck,and the size of the traditional flap is sometimes not enough to repair large defects.Thus,combining soft tissue expansion with a vascular supercharging technique,we propose a novel design of MS-LD flap,as well as its application strategy.展开更多
Objective:To explore the clinical value of autologous skull transplantation in the treatment of skull defects.Methods:Sixty-six patients who underwent skull defect reconstruction treatment in our hospital from January...Objective:To explore the clinical value of autologous skull transplantation in the treatment of skull defects.Methods:Sixty-six patients who underwent skull defect reconstruction treatment in our hospital from January 2022 to March 2024 were selected and divided into an autologous skull transplantation group(n=31)and an artificial bone transplantation material group(n=35)based on different bone transplantation materials.The two groups of patients were followed up for 12 months to observe the bone healing and the incidence of postoperative complications.Results:After 9 months of treatment,the bone healing performance of the autologous skull transplantation group was better than that of the artificial bone transplantation material group(P<0.05).By the end of the last follow-up,the incidence of bony postoperative complications in the autologous skull transplantation group was lower than that in the artificial bone transplantation material group(P<0.05).Conclusion:Autologous skull repair for skull defects has good biocompatibility,can promote bone healing,and reduce the incidence of postoperative complications.展开更多
The ultrasonic guided wave technology plays a significant role in the field of non-destructive testing as it employs acoustic waves with the advantages of high propagation efficiency and low energy consumption during ...The ultrasonic guided wave technology plays a significant role in the field of non-destructive testing as it employs acoustic waves with the advantages of high propagation efficiency and low energy consumption during the inspect process.However,the theoretical solutions to guided wave scattering problems with assumptions such as the Born approximation have led to the poor quality of the reconstructed results.Besides,the scattering signals collected from industry sectors are often noised and nonstationary.To address these issues,a novel physics-informed framework(PIF)for the quantitative reconstruction of defects by means of the integration of the data-driven method with the guided wave scattering analysis is proposed in this paper.Based on the geometrical information of defects and initial results obtained by the PIF-based analysis of defect reconstructions,a deep-learning neural network model is built to reveal the physical relationship between the defects and the noisy detection signals.This learning model is then adopted to assess and characterize the defect profiles in structures,improve the accuracy of the analytical model,and eliminate the impact of the noise pollution in the process of inspection.To demonstrate the advantages of the developed PIF for the complex defect reconstructions with the capability of denoising,several numerical examples are carried out.The results show that the PIF has greater accuracy for the reconstruction of defects in the structures than the analytical method,and provides a valuable insight into the development of artificial intelligence(AI)-assisted inspection systems with high accuracy and efficiency in the fields of structural integrity and condition monitoring.展开更多
To reconstruct tracheal defect after tumor excision,we used the contralateral musculo-periosteum flap of the sternocleidomastoideus with clavicular periosteum.Methods The contralateral musculo-periosteum flap of the s...To reconstruct tracheal defect after tumor excision,we used the contralateral musculo-periosteum flap of the sternocleidomastoideus with clavicular periosteum.Methods The contralateral musculo-periosteum flap of the sternocleidomastoideus with clavicular periosteum was used to reconstruct the tracheal defect when the blood supply to the ipsilateral sternocleidomastoideus was destroyed because of lymphonode clearing or radiotherapy.The pedicle of the musculo-periosteum flap was dissected adequately and the blood supply was protected carefully.Results All flaps survived with epithelization and osteogenesis.The endotracheal tubes were pulled out safely without trachea stenosis in all the patients.Conclusion The contralateral musculo-periosteum flap of the sternocleidomastoideus with clavicular periosteum could reconstruct the tracheal defect when the ipsilateral blood supply was damaged.This method extends the application of the musculo-periosteum flap.3 refs,4 figs.展开更多
We investigated the osteogenic characteristic and biodegradation behavior of porous beta-tricalcitum phosphate （ β- TCP ） and bone morphogenetic protein/beta-tricalcium phosphate （ BMP/ β- TCP ） complex in mand...We investigated the osteogenic characteristic and biodegradation behavior of porous beta-tricalcitum phosphate （ β- TCP ） and bone morphogenetic protein/beta-tricalcium phosphate （ BMP/ β- TCP ） complex in mandibular reconstruction and evaluated the advantages of BMP / β- TCP complex in repairing bone defects. Bone defects created in the lower margin of bilateral mandible bodies in 12 rabbits were repaired with β- TCP （ control group ） and BMP/ β- TCP complex （ experimental group ） respectively. The rabbits were euthanized after 2, 4, 8 and 12 weeks and examined by macroscopy, radiography, histology, histomorphometry and image analysis. 2 weeks after surgery, ossftcation of newly-generated tissue in BMP/ β- TCP complex group appeared and after 12 weeks, massive new bone and ossification maturation were seen. However, in β- TCP group without BMP , ossification was not found until 12 weeks after operation. Image analysis showed that bone regeneration rate of BMP/ β- TCP was 30%-40% higher and the degradation rate was 20%- 30% higher than that of β- TCP. Therefore, as a reconstructive material for bone defects, BMP/ β-TCP complex is superior to β-TCP and can be used in oral and maxillofacial surgery.展开更多
This case report describes the use of a Functional Thenar Eminence myocutaneous flap for reconstruction of volar defect of distal right thumb of a 25-year-old male who sustained a twisting injury while working. Part o...This case report describes the use of a Functional Thenar Eminence myocutaneous flap for reconstruction of volar defect of distal right thumb of a 25-year-old male who sustained a twisting injury while working. Part of bone and tendon were exposed and the tip of the distal phalanx was crushed, with bony defect.展开更多
At this stage,bone defects caused by trauma,infection,tumor,or congenital diseases are generally filled with autologous bone or allogeneic bone transplantation,but this treatment method has limited sources,potential d...At this stage,bone defects caused by trauma,infection,tumor,or congenital diseases are generally filled with autologous bone or allogeneic bone transplantation,but this treatment method has limited sources,potential disease transmission and other problems.Ideal bone-graft materials remain continuously explored,and bone defect reconstruction remains a significant challenge.Mineralized collagen prepared by bionic mineralization combining organic polymer collagen with inorganic mineral calcium phosphate can effectively imitate the composition and hierarchical structure of natural bone and has good application value in bone repair materials.Magnesium,strontium,zinc and other inorganic components not only can activate relevant signaling pathways to induce differentiation of osteogenic precursor cells but also stimulate other core biological processes of bone tissue growth and play an important role in natural bone growth,and bone repair and reconstruction.This study reviewed the advances in hydroxyapatite/collagen composite scaffolds and osseointegration with natural bone inorganic components,such as magnesium,strontium and zinc.展开更多
Three-dimensional printed Ti-6Al-4V hemipelvic prosthesis has become a current popular method for pelvic defect reconstruction.This paper presents a novel biomimetic hemipelvic prosthesis design that utilises patient-...Three-dimensional printed Ti-6Al-4V hemipelvic prosthesis has become a current popular method for pelvic defect reconstruction.This paper presents a novel biomimetic hemipelvic prosthesis design that utilises patient-specific anatomical data in conjunction with the Voronoi diagram algorithm.Unlike traditional design methods that rely on fixed,homogeneous unit cell,the Voronoi diagram enables to create imitation of trabecular structure(ITS).The proposed approach was conducted for six patients.The entire contour of the customised prosthesis matched well with the residual bone.The porosity and pore size of the ITS were evaluated.The distribution of the pore size ranged from 500 to 1400μm.Porosity calculations indicated the average porosity was 63.13±0.30%.Cubic ITS samples were fabricated for micrograph and mechanical analysis.Scanning electron microscopy images of the ITS samples exhibited rough surface morphology without obvious defects.The Young’s modulus and compressive strength were 1.68±0.05 GPa and 174±8 MPa,respectively.Post-operative X-rays confirmed proper matching of the customised prostheses with the bone defect.Tomosynthesis-Shimadzu metal artifact reduction technology images indicated close contact between the implant and host bone,alongside favourable bone density and absence of resorption or osteolysis around the implant.At the last follow-up,the average Musculoskeletal Tumour Society score was 23.2(range,21-26).By leveraging additive manufacturing and Voronoi diagram algorithm,customised implants tailored to individual patient anatomy can be fabricated,offering wide distribution of the pore size,reasonable mechanical properties,favourable osseointegration,and satisfactory function.展开更多
To the Editor Tissue expanders have been widely used in plastic and reconstructive surgery.They induce skin regeneration through mechanical tension and generate new tissue to repair and reconstruct soft tissue defects...To the Editor Tissue expanders have been widely used in plastic and reconstructive surgery.They induce skin regeneration through mechanical tension and generate new tissue to repair and reconstruct soft tissue defects throughout the body[1].The scalp,with its rich blood supply,vigorous cell proliferation and abundant hair follicle stem cells,can yield a significant amount of hair-bearing skin after expansion[2].展开更多
基金supported by the UK EPSRC Platform Grant:Through-life performance:From science to instrumentation(Grant No.EP/P027121/1).
文摘Although machine Learning has demonstrated exceptional applicability in thermographic inspection,precise defect reconstruction is still challenging,especially for complex defect profiles with limited defect sample diversity.Thus,this paper proposes a self-enhancement defect reconstruction technique based on cycle-consistent generative adversarial network(Cycle-GAN)that accurately characterises complex defect profiles and generates reliable artificial thermal images for dataset augmentation,enhancing defect characterisation.By using a synthetic dataset from simulation and experiments,the network overcomes the limited samples problem by learning the diversity of complex defects from finite element modelling and obtaining the thermography uncertainty patterns from practical experiments.Then,an iterative strategy with a self-enhancement capability optimises the characterisation accuracy and data generation performance.The designed loss function structure with cycle consistency and identity loss constrains the GAN’s transfer variation to guarantee augmented data quality and defect reconstruction accuracy simultaneously,while the self-enhancement results significantly improve accuracy in thermal images and defect profile reconstruction.The experimental results demonstrate the feasibility of the proposed method by attaining high accuracy with optimal loss norm for defect profile reconstruction with a Recall score over 0.92.The scalability investigation of different materials and defect types is also discussed,highlighting its capability for diverse thermography quantification and automated inspection scenarios.
文摘BACKGROUND Total pharyngo-laryngo-esophagectomy with a reconstruction of gastric pull-up is the most common treatment method for patients with multiple primary upper digestive tract carcinomas,such as hypopharyngeal carcinoma with thoracic esophageal carcinoma.However,neck circumferential defect and tracheoesophageal fistula after gastric necrosis are still challenging problems for surgeons and patients.CASE SUMMARY This case report presents 2 patients who underwent reconstructive surgeries using 4 local random flaps with a split thickness skin graft in the first case,and 6 local random flaps in the second case to close the circumferential defect and tracheoesophageal fistula after failed gastric pull-up.Both patients achieved good swallowing function and could take solid diet without dysphagia postoperatively.CONCLUSION For selected patients,local random flaps(with a split thickness skin graft)can be a simple and reliable solution for reconstructing tracheoesophageal fistula or cervical circumferential defect after gastric necrosis,especially when the necrosis extends below the thoracic inlet.
基金supported by National Natural Science Foundation of China(82072177,82272264)the‘Hengjie’Program of Shanghai Health Youth Talent Reward Foundation.
文摘To the editor In 2003,Schwabegger et al.proposed the muscle-sparing latissimus dorsi(MS-LD)flap[1],which preserved a portion of the latissimus dorsi(LD)muscle around the point where the thoracodorsal artery(TDA)perforator penetrates the muscle,having the advantages of a sufficient flap blood supply and reduced donor-site morbidity.However,the traditional MS-LD flap is still too bulky for the reconstruction of defects of the face and neck,and the size of the traditional flap is sometimes not enough to repair large defects.Thus,combining soft tissue expansion with a vascular supercharging technique,we propose a novel design of MS-LD flap,as well as its application strategy.
文摘Objective:To explore the clinical value of autologous skull transplantation in the treatment of skull defects.Methods:Sixty-six patients who underwent skull defect reconstruction treatment in our hospital from January 2022 to March 2024 were selected and divided into an autologous skull transplantation group(n=31)and an artificial bone transplantation material group(n=35)based on different bone transplantation materials.The two groups of patients were followed up for 12 months to observe the bone healing and the incidence of postoperative complications.Results:After 9 months of treatment,the bone healing performance of the autologous skull transplantation group was better than that of the artificial bone transplantation material group(P<0.05).By the end of the last follow-up,the incidence of bony postoperative complications in the autologous skull transplantation group was lower than that in the artificial bone transplantation material group(P<0.05).Conclusion:Autologous skull repair for skull defects has good biocompatibility,can promote bone healing,and reduce the incidence of postoperative complications.
基金supported by the National Natural Science Foundation of China(Nos.12061131013,12211530064,and 12172171)the Fundamental Research Funds for the Central Universities of China(Nos.NE2020002 and NS2019007)+4 种基金the National Natural Science Foundation of China for Creative Research Groups(No.51921003)the Postgraduate Research and Practice Innovation Program of Jiangsu Province of China(No.KYCX210184)the National Natural Science Foundation of Jiangsu Province of China(No.BK20211176)the State Key Laboratory of Mechanics and Control of Mechanical Structures at Nanjing University of Aeronautics and Astronautics of China(No.MCMS-E0520K02)the Interdisciplinary Innovation Fund for Doctoral Students of Nanjing University of Aeronautics and Astronautics of China(No.KXKCXJJ202208)。
文摘The ultrasonic guided wave technology plays a significant role in the field of non-destructive testing as it employs acoustic waves with the advantages of high propagation efficiency and low energy consumption during the inspect process.However,the theoretical solutions to guided wave scattering problems with assumptions such as the Born approximation have led to the poor quality of the reconstructed results.Besides,the scattering signals collected from industry sectors are often noised and nonstationary.To address these issues,a novel physics-informed framework(PIF)for the quantitative reconstruction of defects by means of the integration of the data-driven method with the guided wave scattering analysis is proposed in this paper.Based on the geometrical information of defects and initial results obtained by the PIF-based analysis of defect reconstructions,a deep-learning neural network model is built to reveal the physical relationship between the defects and the noisy detection signals.This learning model is then adopted to assess and characterize the defect profiles in structures,improve the accuracy of the analytical model,and eliminate the impact of the noise pollution in the process of inspection.To demonstrate the advantages of the developed PIF for the complex defect reconstructions with the capability of denoising,several numerical examples are carried out.The results show that the PIF has greater accuracy for the reconstruction of defects in the structures than the analytical method,and provides a valuable insight into the development of artificial intelligence(AI)-assisted inspection systems with high accuracy and efficiency in the fields of structural integrity and condition monitoring.
文摘To reconstruct tracheal defect after tumor excision,we used the contralateral musculo-periosteum flap of the sternocleidomastoideus with clavicular periosteum.Methods The contralateral musculo-periosteum flap of the sternocleidomastoideus with clavicular periosteum was used to reconstruct the tracheal defect when the blood supply to the ipsilateral sternocleidomastoideus was destroyed because of lymphonode clearing or radiotherapy.The pedicle of the musculo-periosteum flap was dissected adequately and the blood supply was protected carefully.Results All flaps survived with epithelization and osteogenesis.The endotracheal tubes were pulled out safely without trachea stenosis in all the patients.Conclusion The contralateral musculo-periosteum flap of the sternocleidomastoideus with clavicular periosteum could reconstruct the tracheal defect when the ipsilateral blood supply was damaged.This method extends the application of the musculo-periosteum flap.3 refs,4 figs.
文摘We investigated the osteogenic characteristic and biodegradation behavior of porous beta-tricalcitum phosphate （ β- TCP ） and bone morphogenetic protein/beta-tricalcium phosphate （ BMP/ β- TCP ） complex in mandibular reconstruction and evaluated the advantages of BMP / β- TCP complex in repairing bone defects. Bone defects created in the lower margin of bilateral mandible bodies in 12 rabbits were repaired with β- TCP （ control group ） and BMP/ β- TCP complex （ experimental group ） respectively. The rabbits were euthanized after 2, 4, 8 and 12 weeks and examined by macroscopy, radiography, histology, histomorphometry and image analysis. 2 weeks after surgery, ossftcation of newly-generated tissue in BMP/ β- TCP complex group appeared and after 12 weeks, massive new bone and ossification maturation were seen. However, in β- TCP group without BMP , ossification was not found until 12 weeks after operation. Image analysis showed that bone regeneration rate of BMP/ β- TCP was 30%-40% higher and the degradation rate was 20%- 30% higher than that of β- TCP. Therefore, as a reconstructive material for bone defects, BMP/ β-TCP complex is superior to β-TCP and can be used in oral and maxillofacial surgery.
文摘This case report describes the use of a Functional Thenar Eminence myocutaneous flap for reconstruction of volar defect of distal right thumb of a 25-year-old male who sustained a twisting injury while working. Part of bone and tendon were exposed and the tip of the distal phalanx was crushed, with bony defect.
基金supported by the National Natural Science Foundation of China(grant no.82102584)the National Key R&D Program of China(grant no.2020YFC1107601).
文摘At this stage,bone defects caused by trauma,infection,tumor,or congenital diseases are generally filled with autologous bone or allogeneic bone transplantation,but this treatment method has limited sources,potential disease transmission and other problems.Ideal bone-graft materials remain continuously explored,and bone defect reconstruction remains a significant challenge.Mineralized collagen prepared by bionic mineralization combining organic polymer collagen with inorganic mineral calcium phosphate can effectively imitate the composition and hierarchical structure of natural bone and has good application value in bone repair materials.Magnesium,strontium,zinc and other inorganic components not only can activate relevant signaling pathways to induce differentiation of osteogenic precursor cells but also stimulate other core biological processes of bone tissue growth and play an important role in natural bone growth,and bone repair and reconstruction.This study reviewed the advances in hydroxyapatite/collagen composite scaffolds and osseointegration with natural bone inorganic components,such as magnesium,strontium and zinc.
基金supported by Qingdao Research Institutes of Sichuan University,Research of Biomedical Materials and 3D Printing Related Products(No.20GZ30301).
文摘Three-dimensional printed Ti-6Al-4V hemipelvic prosthesis has become a current popular method for pelvic defect reconstruction.This paper presents a novel biomimetic hemipelvic prosthesis design that utilises patient-specific anatomical data in conjunction with the Voronoi diagram algorithm.Unlike traditional design methods that rely on fixed,homogeneous unit cell,the Voronoi diagram enables to create imitation of trabecular structure(ITS).The proposed approach was conducted for six patients.The entire contour of the customised prosthesis matched well with the residual bone.The porosity and pore size of the ITS were evaluated.The distribution of the pore size ranged from 500 to 1400μm.Porosity calculations indicated the average porosity was 63.13±0.30%.Cubic ITS samples were fabricated for micrograph and mechanical analysis.Scanning electron microscopy images of the ITS samples exhibited rough surface morphology without obvious defects.The Young’s modulus and compressive strength were 1.68±0.05 GPa and 174±8 MPa,respectively.Post-operative X-rays confirmed proper matching of the customised prostheses with the bone defect.Tomosynthesis-Shimadzu metal artifact reduction technology images indicated close contact between the implant and host bone,alongside favourable bone density and absence of resorption or osteolysis around the implant.At the last follow-up,the average Musculoskeletal Tumour Society score was 23.2(range,21-26).By leveraging additive manufacturing and Voronoi diagram algorithm,customised implants tailored to individual patient anatomy can be fabricated,offering wide distribution of the pore size,reasonable mechanical properties,favourable osseointegration,and satisfactory function.
基金Funding was provided by Clinical Research Program of Ninth People’s Hospital,Shanghai JiaoTong University School of Medicine(JYLJ202103)The Two-hundred Talent(20191916)the Shanghai Clinical Research Center of Plastic and Reconstructive Surgery supported by the Science and Technology Commission of Shanghai Municipality(22MC1940300).
文摘To the Editor Tissue expanders have been widely used in plastic and reconstructive surgery.They induce skin regeneration through mechanical tension and generate new tissue to repair and reconstruct soft tissue defects throughout the body[1].The scalp,with its rich blood supply,vigorous cell proliferation and abundant hair follicle stem cells,can yield a significant amount of hair-bearing skin after expansion[2].
